岡本 郁弘

最終更新日時: 2021/07/05 17:48:56

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氏名(漢字/フリガナ/アルファベット表記)
岡本 郁弘/オカモト イクヒロ/Okamoto, Ikuhiro
所属部署・職名(部局/所属/講座等/職名)
高等研究院/ヒト生物学高等研究拠点/特定講師
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
修士(地球環境科学) 北海道大学
博士(地球環境科学) 北海道大学
ORCID ID
https://orcid.org/0000-0002-2870-8321
researchmap URL
https://researchmap.jp/7000009233
研究テーマ
(日本語)
哺乳類の雌におけるX染色体の不活性化
(英語)
X chromosome inactivation in mammals
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
X 染色体 X chromosome
エピジェネティクス epigenetics
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Sakai Y, Nakamura T, Okamoto I, Gyobu-Motani S, Ohta H, Yabuta Y, Tsukiyama T, Iwatani C, Tsuchiya H, Ema M, Morizane A, Takahashi J, Yamamoto T, Saitou M Sakai Y, Nakamura T, Okamoto I, Gyobu-Motani S, Ohta H, Yabuta Y, Tsukiyama T, Iwatani C, Tsuchiya H, Ema M, Morizane A, Takahashi J, Yamamoto T, Saitou M Sakai Y, Nakamura T, Okamoto I, Gyobu-Motani S, Ohta H, Yabuta Y, Tsukiyama T, Iwatani C, Tsuchiya H, Ema M, Morizane A, Takahashi J, Yamamoto T, Saitou M Induction of the Germ-Cell Fate from Pluripotent Stem Cells in Cynomolgus Monkeys. Induction of the Germ-Cell Fate from Pluripotent Stem Cells in Cynomolgus Monkeys. Induction of the Germ-Cell Fate from Pluripotent Stem Cells in Cynomolgus Monkeys. Biology of reproduction Biology of reproduction Biology of reproduction 2019/11 公開
Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG A symmetric toggle switch explains the onset of random X inactivation in different mammals. A symmetric toggle switch explains the onset of random X inactivation in different mammals. A symmetric toggle switch explains the onset of random X inactivation in different mammals. Nature structural & molecular biology, 26, 5, 350-360 Nature structural & molecular biology, 26, 5, 350-360 Nature structural & molecular biology, 26, 5, 350-360 2019/05 公開
Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Science (New York, N.Y.), 362, 6412, 356-360 Science (New York, N.Y.), 362, 6412, 356-360 Science (New York, N.Y.), 362, 6412, 356-360 2018/10 公開
Okamoto I Okamoto I Okamoto I Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Methods in molecular biology (Clifton, N.J.), 1861, 149-159 Methods in molecular biology (Clifton, N.J.), 1861, 149-159 Methods in molecular biology (Clifton, N.J.), 1861, 149-159 2018 公開
Maud Borensztein, Ikuhiro Okamoto, Laurene Syx, Guillaume Guilbaud, Christel Picard, Katia Ancelin, Rafael Galupa, Patricia Diabangouaya, Nicolas Servant, Emmanuel Barillot, Azim Surani, Mitinori Saitou, Chong-Jian Chen, Konstantinos Anastassiadis, Edith Heard Maud Borensztein, Ikuhiro Okamoto, Laurene Syx, Guillaume Guilbaud, Christel Picard, Katia Ancelin, Rafael Galupa, Patricia Diabangouaya, Nicolas Servant, Emmanuel Barillot, Azim Surani, Mitinori Saitou, Chong-Jian Chen, Konstantinos Anastassiadis, Edith Heard Maud Borensztein, Ikuhiro Okamoto, Laurene Syx, Guillaume Guilbaud, Christel Picard, Katia Ancelin, Rafael Galupa, Patricia Diabangouaya, Nicolas Servant, Emmanuel Barillot, Azim Surani, Mitinori Saitou, Chong-Jian Chen, Konstantinos Anastassiadis, Edith Heard Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass NATURE COMMUNICATIONS, 8, 1, 1297 NATURE COMMUNICATIONS, 8, 1, 1297 NATURE COMMUNICATIONS, 8, 1, 1297 2017/11 英語 研究論文(学術雑誌) 公開
Tomonori Nakamura, Yukihiro Yabuta, Ikuhiro Okamoto, Kotaro Sasaki, Chizuru Iwatani, Hideaki Tsuchiya, Mitinori Saitou Tomonori Nakamura, Yukihiro Yabuta, Ikuhiro Okamoto, Kotaro Sasaki, Chizuru Iwatani, Hideaki Tsuchiya, Mitinori Saitou Tomonori Nakamura, Yukihiro Yabuta, Ikuhiro Okamoto, Kotaro Sasaki, Chizuru Iwatani, Hideaki Tsuchiya, Mitinori Saitou Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys Scientific Data, 4, 170067-170067 Scientific Data, 4, 170067-170067 Scientific Data, 4, 170067-170067 2017/06 研究論文(学術雑誌) 公開
Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. In vitro expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. The EMBO journal, 36, 13, 1888-1907 The EMBO journal, 36, 13, 1888-1907 The EMBO journal, 36, 13, 1888-1907 2017/05 研究論文(学術雑誌) 公開
Noémie Ranisavljevic, Ikuhiro Okamoto, Edith Heard, Katia Ancelin Noémie Ranisavljevic, Ikuhiro Okamoto, Edith Heard, Katia Ancelin Noémie Ranisavljevic, Ikuhiro Okamoto, Edith Heard, Katia Ancelin RNA FISH to study zygotic genome activation in early mouse embryos RNA FISH to study zygotic genome activation in early mouse embryos RNA FISH to study zygotic genome activation in early mouse embryos Methods in Molecular Biology, 1605, 133-145 Methods in Molecular Biology, 1605, 133-145 Methods in Molecular Biology, 1605, 133-145 2017 英語 公開
Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. Cell reports, 17, 10, 2789-2804 Cell reports, 17, 10, 2789-2804 Cell reports, 17, 10, 2789-2804 2016/12 研究論文(学術雑誌) 公開
Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. Developmental cell, 39, 2, 169-185 Developmental cell, 39, 2, 169-185 Developmental cell, 39, 2, 169-185 2016/10 研究論文(学術雑誌) 公開
Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M A developmental coordinate of pluripotency among mice, monkeys and humans. A developmental coordinate of pluripotency among mice, monkeys and humans. A developmental coordinate of pluripotency among mice, monkeys and humans. Nature, 537, 7618, 57-62 Nature, 537, 7618, 57-62 Nature, 537, 7618, 57-62 2016/08 研究論文(学術雑誌) 公開
Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 2015/08 研究論文(学術雑誌) 公開
Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. Nucleic acids research, 43, 9, e60 Nucleic acids research, 43, 9, e60 Nucleic acids research, 43, 9, e60 2015/05 研究論文(学術雑誌) 公開
Rachel Duffie, Sophie Ajjan, Maxim V. Greenberg, Natasha Zamudio, Martin Escamilla del Arenal, Julian Iranzo, Ikuhiro Okamoto, Sandrine Barbaux, Patricia Fauque, Deborah Bourc'his Rachel Duffie, Sophie Ajjan, Maxim V. Greenberg, Natasha Zamudio, Martin Escamilla del Arenal, Julian Iranzo, Ikuhiro Okamoto, Sandrine Barbaux, Patricia Fauque, Deborah Bourc'his Rachel Duffie, Sophie Ajjan, Maxim V. Greenberg, Natasha Zamudio, Martin Escamilla del Arenal, Julian Iranzo, Ikuhiro Okamoto, Sandrine Barbaux, Patricia Fauque, Deborah Bourc'his The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals GENES & DEVELOPMENT, 28, 5, 463-478 GENES & DEVELOPMENT, 28, 5, 463-478 GENES & DEVELOPMENT, 28, 5, 463-478 2014/03 英語 研究論文(学術雑誌) 公開
Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network. The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network. The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network. Cell Stem Cell, 14, 2, 203-216 Cell Stem Cell, 14, 2, 203-216 Cell Stem Cell, 14, 2, 203-216 2014/02 英語 研究論文(学術雑誌) 公開
Constance Ciaudo, Florence Jay, Ikuhiro Okamoto, Chong-Jian Chen, Alexis Sarazin, Nicolas Servant, Emmanuel Barillot, Edith Heard, Olivier Voinnet Constance Ciaudo, Florence Jay, Ikuhiro Okamoto, Chong-Jian Chen, Alexis Sarazin, Nicolas Servant, Emmanuel Barillot, Edith Heard, Olivier Voinnet Constance Ciaudo, Florence Jay, Ikuhiro Okamoto, Chong-Jian Chen, Alexis Sarazin, Nicolas Servant, Emmanuel Barillot, Edith Heard, Olivier Voinnet RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells (Retracted article. See vol. 9, e1005519, 2015) RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells (Retracted article. See vol. 9, e1005519, 2015) RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells (Retracted article. See vol. 9, e1005519, 2015) PLOS GENETICS, 9, 11 PLOS GENETICS, 9, 11 PLOS GENETICS, 9, 11 2013/11 英語 研究論文(学術雑誌) 公開
Catherine Patrat, Ikuhiro Okamoto, Edith Heard Catherine Patrat, Ikuhiro Okamoto, Edith Heard Catherine Patrat, Ikuhiro Okamoto, Edith Heard Initiation of X chromosome inactivation during early embryogenesis in mice and in humans Initiation of X chromosome inactivation during early embryogenesis in mice and in humans Initiation of X chromosome inactivation during early embryogenesis in mice and in humans BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 197, 3, 609-617 BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 197, 3, 609-617 BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 197, 3, 609-617 2013/03 フランス語 研究論文(学術雑誌) 公開
Elphege P. Nora, Bryan R. Lajoie, Edda G. Schulz, Luca Giorgetti, Ikuhiro Okamoto, Nicolas Servant, Tristan Piolot, Nynke L. van Berkum, Johannes Meisig, John Sedat, Joost Gribnau, Emmanuel Barillot, Nils Bluethgen, Job Dekker, Edith Heard Elphege P. Nora, Bryan R. Lajoie, Edda G. Schulz, Luca Giorgetti, Ikuhiro Okamoto, Nicolas Servant, Tristan Piolot, Nynke L. van Berkum, Johannes Meisig, John Sedat, Joost Gribnau, Emmanuel Barillot, Nils Bluethgen, Job Dekker, Edith Heard Elphege P. Nora, Bryan R. Lajoie, Edda G. Schulz, Luca Giorgetti, Ikuhiro Okamoto, Nicolas Servant, Tristan Piolot, Nynke L. van Berkum, Johannes Meisig, John Sedat, Joost Gribnau, Emmanuel Barillot, Nils Bluethgen, Job Dekker, Edith Heard Spatial partitioning of the regulatory landscape of the X-inactivation centre Spatial partitioning of the regulatory landscape of the X-inactivation centre Spatial partitioning of the regulatory landscape of the X-inactivation centre NATURE, 485, 7398, 381-385 NATURE, 485, 7398, 381-385 NATURE, 485, 7398, 381-385 2012/05 英語 研究論文(学術雑誌) 公開
Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (vol 472, pg 370, 2011) Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (vol 472, pg 370, 2011) Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (vol 472, pg 370, 2011) NATURE, 474, 7350, 239-240 NATURE, 474, 7350, 239-240 NATURE, 474, 7350, 239-240 2011/06 英語 公開
Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Ikuhiro Okamoto, Catherine Patrat, Dominique Thepot, Nathalie Peynot, Patricia Fauque, Nathalie Daniel, Patricia Diabangouaya, Jean-Philippe Wolf, Jean-Paul Renard, Veronique Duranthon, Edith Heard Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development NATURE, 472, 7343, 370-U141 NATURE, 472, 7343, 370-U141 NATURE, 472, 7343, 370-U141 2011/04 英語 研究論文(学術雑誌) 公開
Aline V. Probst, Ikuhiro Okamoto, Miguel Casanova, Fatima El Marjou, Patricia Le Baccon, Genevieve Almouzni Aline V. Probst, Ikuhiro Okamoto, Miguel Casanova, Fatima El Marjou, Patricia Le Baccon, Genevieve Almouzni Aline V. Probst, Ikuhiro Okamoto, Miguel Casanova, Fatima El Marjou, Patricia Le Baccon, Genevieve Almouzni A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development DEVELOPMENTAL CELL, 19, 4, 625-638 DEVELOPMENTAL CELL, 19, 4, 625-638 DEVELOPMENTAL CELL, 19, 4, 625-638 2010/10 英語 研究論文(学術雑誌) 公開
Ikuhiro Okamoto, Edith Heard Ikuhiro Okamoto, Edith Heard Ikuhiro Okamoto, Edith Heard Lessons from comparative analysis of X-chromosome inactivation in mammals Lessons from comparative analysis of X-chromosome inactivation in mammals Lessons from comparative analysis of X-chromosome inactivation in mammals CHROMOSOME RESEARCH, 17, 5, 659-669 CHROMOSOME RESEARCH, 17, 5, 659-669 CHROMOSOME RESEARCH, 17, 5, 659-669 2009/07 英語 研究論文(学術雑誌) 公開
Hisanobu Oda, Ikuhiro Okamoto, Niall Murphy, Jianhua Chu, Sandy M. Price, Michael M. Shen, Maria Elena Torres-Padilla, Edith Heard, Danny Reinberg Hisanobu Oda, Ikuhiro Okamoto, Niall Murphy, Jianhua Chu, Sandy M. Price, Michael M. Shen, Maria Elena Torres-Padilla, Edith Heard, Danny Reinberg Hisanobu Oda, Ikuhiro Okamoto, Niall Murphy, Jianhua Chu, Sandy M. Price, Michael M. Shen, Maria Elena Torres-Padilla, Edith Heard, Danny Reinberg Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development MOLECULAR AND CELLULAR BIOLOGY, 29, 8, 2278-2295 MOLECULAR AND CELLULAR BIOLOGY, 29, 8, 2278-2295 MOLECULAR AND CELLULAR BIOLOGY, 29, 8, 2278-2295 2009/04 英語 研究論文(学術雑誌) 公開
I. Okamoto, E. Heard I. Okamoto, E. Heard I. Okamoto, E. Heard The dynamics of imprinted X inactivation during preimplantation development in mice The dynamics of imprinted X inactivation during preimplantation development in mice The dynamics of imprinted X inactivation during preimplantation development in mice CYTOGENETIC AND GENOME RESEARCH, 113, 1-4, 318-324 CYTOGENETIC AND GENOME RESEARCH, 113, 1-4, 318-324 CYTOGENETIC AND GENOME RESEARCH, 113, 1-4, 318-324 2006 英語 研究論文(学術雑誌) 公開
Okamoto, I, D Arnaud, P Le Baccon, AP Otte, CM Disteche, P Avner, E Heard Okamoto, I, D Arnaud, P Le Baccon, AP Otte, CM Disteche, P Avner, E Heard Okamoto, I, D Arnaud, P Le Baccon, AP Otte, CM Disteche, P Avner, E Heard Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice NATURE, 438, 7066, 369-373 NATURE, 438, 7066, 369-373 NATURE, 438, 7066, 369-373 2005/11 英語 研究論文(学術雑誌) 公開
SQ Bao, N Miyoshi, Okamoto, I, T Jenuwein, E Heard, MA Surani SQ Bao, N Miyoshi, Okamoto, I, T Jenuwein, E Heard, MA Surani SQ Bao, N Miyoshi, Okamoto, I, T Jenuwein, E Heard, MA Surani Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte EMBO REPORTS, 6, 8, 748-754 EMBO REPORTS, 6, 8, 748-754 EMBO REPORTS, 6, 8, 748-754 2005/08 英語 研究論文(学術雑誌) 公開
T Kunath, D Arnaud, GD Uy, L Okamoto, C Chureau, Y Yamanaka, E Heard, RL Gardner, P Avner, J Rossant T Kunath, D Arnaud, GD Uy, L Okamoto, C Chureau, Y Yamanaka, E Heard, RL Gardner, P Avner, J Rossant T Kunath, D Arnaud, GD Uy, L Okamoto, C Chureau, Y Yamanaka, E Heard, RL Gardner, P Avner, J Rossant Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts DEVELOPMENT, 132, 7, 1649-1661 DEVELOPMENT, 132, 7, 1649-1661 DEVELOPMENT, 132, 7, 1649-1661 2005/04 英語 研究論文(学術雑誌) 公開
E Heard, J Chaumeil, O Masui, Okamoto, I E Heard, J Chaumeil, O Masui, Okamoto, I E Heard, J Chaumeil, O Masui, Okamoto, I Mammalian X-chromosome inactivation: An epigenetics paradigm Mammalian X-chromosome inactivation: An epigenetics paradigm Mammalian X-chromosome inactivation: An epigenetics paradigm COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 69, 89-102 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 69, 89-102 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 69, 89-102 2004 英語 研究論文(学術雑誌) 公開
J Chaumeil, Okamoto, I, E Heard J Chaumeil, Okamoto, I, E Heard J Chaumeil, Okamoto, I, E Heard X-chromosome inactivation in mouse embryonic stem cells: Analysis of histone modifications and transcriptional activity using immunofluorescence and FISH X-chromosome inactivation in mouse embryonic stem cells: Analysis of histone modifications and transcriptional activity using immunofluorescence and FISH X-chromosome inactivation in mouse embryonic stem cells: Analysis of histone modifications and transcriptional activity using immunofluorescence and FISH CHROMATIN AND CHROMATIN REMODELING ENZYMES, PT B, 376, 405-+ CHROMATIN AND CHROMATIN REMODELING ENZYMES, PT B, 376, 405-+ CHROMATIN AND CHROMATIN REMODELING ENZYMES, PT B, 376, 405-+ 2004 英語 公開
Okamoto, I, AP Otte, CD Allis, D Reinberg, E Heard Okamoto, I, AP Otte, CD Allis, D Reinberg, E Heard Okamoto, I, AP Otte, CD Allis, D Reinberg, E Heard Epigenetic dynamics of imprinted X inactivation during early mouse development Epigenetic dynamics of imprinted X inactivation during early mouse development Epigenetic dynamics of imprinted X inactivation during early mouse development SCIENCE, 303, 5658, 644-649 SCIENCE, 303, 5658, 644-649 SCIENCE, 303, 5658, 644-649 2004/01 英語 研究論文(学術雑誌) 公開
H Mizuno, Okamoto, I, N Takagi H Mizuno, Okamoto, I, N Takagi H Mizuno, Okamoto, I, N Takagi Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome GENES & GENETIC SYSTEMS, 77, 4, 269-276 GENES & GENETIC SYSTEMS, 77, 4, 269-276 GENES & GENETIC SYSTEMS, 77, 4, 269-276 2002/08 英語 研究論文(学術雑誌) 公開
J Chaumeil, Okamoto, I, M Guggiari, E Heard J Chaumeil, Okamoto, I, M Guggiari, E Heard J Chaumeil, Okamoto, I, M Guggiari, E Heard Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells CYTOGENETIC AND GENOME RESEARCH, 99, 1-4, 75-84 CYTOGENETIC AND GENOME RESEARCH, 99, 1-4, 75-84 CYTOGENETIC AND GENOME RESEARCH, 99, 1-4, 75-84 2002 英語 研究論文(学術雑誌) 公開
Okamoto, I, SS Tan, N Takagi Okamoto, I, SS Tan, N Takagi Okamoto, I, SS Tan, N Takagi X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation DEVELOPMENT, 127, 19, 4137-4145 DEVELOPMENT, 127, 19, 4137-4145 DEVELOPMENT, 127, 19, 4137-4145 2000/10 英語 研究論文(学術雑誌) 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Shoma Matsumoto, Christopher J Porter, Naomi Ogasawara, Chizuru Iwatani, Hideaki Tsuchiya, Yasunari Seita, Yu-Wei Chang, Ikuhiro Okamoto, Mitinori Saitou, Masatsugu Ema, Theodore J Perkins, William L Stanford, Satoshi Tanaka Shoma Matsumoto, Christopher J Porter, Naomi Ogasawara, Chizuru Iwatani, Hideaki Tsuchiya, Yasunari Seita, Yu-Wei Chang, Ikuhiro Okamoto, Mitinori Saitou, Masatsugu Ema, Theodore J Perkins, William L Stanford, Satoshi Tanaka Shoma Matsumoto, Christopher J Porter, Naomi Ogasawara, Chizuru Iwatani, Hideaki Tsuchiya, Yasunari Seita, Yu-Wei Chang, Ikuhiro Okamoto, Mitinori Saitou, Masatsugu Ema, Theodore J Perkins, William L Stanford, Satoshi Tanaka Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts. Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts. Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts. Scientific reports, 10, 1, 6827-6827 Scientific reports, 10, 1, 6827-6827 Scientific reports, 10, 1, 6827-6827 2020/04/22 英語 公開
タイトル言語:
外部資金:競争的資金 (科学研究費補助金)
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 2013〜2016
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 霊長類におけるX染色体不活性化機構の解明 (平成30年度分) 2018/04/01〜2019/03/31
基盤研究(C) 代表 霊長類におけるX染色体不活性化機構の解明 (2019年度分) 2019/04/01〜2020/03/31
基盤研究(C) 代表 霊長類におけるX染色体不活性化機構の解明 (2020年度分) 2020/04/01〜2021/03/31
学外非常勤講師
講義名(日本語) 講義名(英語) 開講期 学校名 学部/研究科名 期間
分子生物学特論 前期 北海道大学 大学院生命科学院 2013/06/21〜2013/06/21
大学院特別セミナー 医学特論 後期 富山大学 医学薬学教育部 2018/10/01〜2018/10/01