清水 章

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氏名(漢字/フリガナ/アルファベット表記)
清水 章/シミズ アキラ/Akira Shimizu
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/臨床研究総合センター/教授
協力講座
部局 所属 講座等 職名
生命科学研究科 高次生命科学専攻 高次生体機能学講座 教授
学内兼務
部局 所属 講座等 職名
医学研究科 医学研究科 医学専攻 大学院担当教授
生命科学研究科 生命科学研究科 高次生命科学専攻 教授
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8507 京都府京都市左京区聖護院川原町54 54 Shogoin-Kawahara-cho, Sakyo-ku,Kyoto 606-8507 Japan
連絡先電話番号
種別 番号
職場 075-751-4719
所属学会(国内)
学会名(日本語) 学会名(英語)
日本生化学会 The Japanese Biochmical Society
日本免疫学会 The Molecular Biology Society of Japan
日本分子生物学会 Japanese Society for Immunology
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
医学博士 大阪大学
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
大阪大学 大学院医学研究科博士課程生理系専攻 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
東京大学 医学部医学科 卒業
出身高等学校
高等学校名 ふりがな
武蔵高等学校 むさしこうとうがっこう
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
1983/04/01〜1984/04/15 大阪大学医学部 Osaka University Medical School 助手 Assistant Professor
1984/04/16〜1988/12/31 京都大学医学部 Faculty of Medicine, Kyoto Uinversity 助手 Assistant Professor
1986/06/18〜1987/12/24 Harvard Medical School Harvard Medical School 研究員 Research Fellow
1988/01/01〜1988/04/07 京都大学医学部 Faculty of Medicine, Kyoto Uinversity 講師 Lecturer
1988/04/08〜1994/11/30 京都大学遺伝子実験施設 Center for Molecular Biology and Genetics 助教授 Associate Professor
1992/12/01〜2004/03/31 京都大学遺伝子実験施設 Center for Molecular Biology and Medicine 教授 Professor
1999/03/01〜2004/03/31 京都大学遺伝子実験施設 Center for Molecular Biology and Genetics 施設長 Director
2001/10/16〜2015 京都大学医学部附属病院 Kyoto University Hospital 教授 Professor
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
遺伝子構造、遺伝子発現 gene organization, gene expression, immunoglobulin, TCR, chromatin structure
探索医療、医療開発 translational research, medical development
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Ikeda, T., Sugie, T., Shimizu, A. and Toi, M. Ikeda, T., Sugie, T., Shimizu, A. and Toi, M. Ikeda, T., Sugie, T., Shimizu, A. and Toi, M. Patterns of clinical practice for sentinel lymph node biopsy in women with node-negative breast cancer: the results of a national survey in Japan. Patterns of clinical practice for sentinel lymph node biopsy in women with node-negative breast cancer: the results of a national survey in Japan. Patterns of clinical practice for sentinel lymph node biopsy in women with node-negative breast cancer: the results of a national survey in Japan. Breast Cancer,24,2,341-344 Breast Cancer,24,2,341-344 Breast Cancer,24,2,341-344 2017/03 英語 研究論文(学術雑誌) 公開
Sugie, T., Ikeda, T., Kawaguchi, A, Shimizu, A. and Toi, M. Sugie, T., Ikeda, T., Kawaguchi, A, Shimizu, A. and Toi, M. Sugie, T., Ikeda, T., Kawaguchi, A, Shimizu, A. and Toi, M. Sentinel lymph node biopsy using indocyanine green fluorescence in early-stage breast cancer: a meta-analysis. Sentinel lymph node biopsy using indocyanine green fluorescence in early-stage breast cancer: a meta-analysis. Sentinel lymph node biopsy using indocyanine green fluorescence in early-stage breast cancer: a meta-analysis. Internat. J. Clin. Oncology,1-7 Internat. J. Clin. Oncology,1-7 Internat. J. Clin. Oncology,1-7 2017/02 英語 研究論文(学術雑誌) 公開
Nishio, H., Minakata, K., Kawaguchi, A., Kumagai, M., Ikeda, T., Shimizu, A., Yokode, M., Morita, S. and Sakata, R. Nishio, H., Minakata, K., Kawaguchi, A., Kumagai, M., Ikeda, T., Shimizu, A., Yokode, M., Morita, S. and Sakata, R. Nishio, H., Minakata, K., Kawaguchi, A., Kumagai, M., Ikeda, T., Shimizu, A., Yokode, M., Morita, S. and Sakata, R. Transcutaneous oxygen pressure as a surrogate index of lower limb amputation. Transcutaneous oxygen pressure as a surrogate index of lower limb amputation. Transcutaneous oxygen pressure as a surrogate index of lower limb amputation. Internat. Angiology,35,6,565-572 Internat. Angiology,35,6,565-572 Internat. Angiology,35,6,565-572 2016/12 英語 研究論文(学術雑誌) 公開
Nakagawa, T., Yamamoto, M., Kumakawa, K., Usami, S., Hato, N., Tabuchi, K., Takahashi, M., Fujiwara, K., Sasaki, A., Komune, S., Yamamoto, N., Hiraumi, H., Sakamoto, T., Shimizu, A. and Ito, J. Nakagawa, T., Yamamoto, M., Kumakawa, K., Usami, S., Hato, N., Tabuchi, K., Takahashi, M., Fujiwara, K., Sasaki, A., Komune, S., Yamamoto, N., Hiraumi, H., Sakamoto, T., Shimizu, A. and Ito, J. Nakagawa, T., Yamamoto, M., Kumakawa, K., Usami, S., Hato, N., Tabuchi, K., Takahashi, M., Fujiwara, K., Sasaki, A., Komune, S., Yamamoto, N., Hiraumi, H., Sakamoto, T., Shimizu, A. and Ito, J. Prognostic Impact of Salvage Treatment on Hearing Recovery in Patients with Sudden Sensorineural Hearing Loss Refractory to Systemic Corticosteroids: A retrospective Observational Study Prognostic Impact of Salvage Treatment on Hearing Recovery in Patients with Sudden Sensorineural Hearing Loss Refractory to Systemic Corticosteroids: A retrospective Observational Study Prognostic Impact of Salvage Treatment on Hearing Recovery in Patients with Sudden Sensorineural Hearing Loss Refractory to Systemic Corticosteroids: A retrospective Observational Study Auris Nasus Larynx,43,5,494 Auris Nasus Larynx,43,5,494 Auris Nasus Larynx,43,5,494 2016/10 英語 研究論文(学術雑誌) 公開
Kuroda, Y., Asada, R., So, K., Yonezawa, A., Nankaku, M., Mukai, K., Ito-Ihara, T., Tada, H., Yamamoto, M., Murayama, T., Morita, S., Tabata, Y., Yokode, M., Shimizu, A., Matsuda, S., and Akiyama, H. Kuroda, Y., Asada, R., So, K., Yonezawa, A., Nankaku, M., Mukai, K., Ito-Ihara, T., Tada, H., Yamamoto, M., Murayama, T., Morita, S., Tabata, Y., Yokode, M., Shimizu, A., Matsuda, S., and Akiyama, H. Kuroda, Y., Asada, R., So, K., Yonezawa, A., Nankaku, M., Mukai, K., Ito-Ihara, T., Tada, H., Yamamoto, M., Murayama, T., Morita, S., Tabata, Y., Yokode, M., Shimizu, A., Matsuda, S., and Akiyama, H. A pilot study of regenerative therapy using controlled release of recombinant human fibroblast growth factor for patients with pre-collapse osteonecrosis of the femoral head. A pilot study of regenerative therapy using controlled release of recombinant human fibroblast growth factor for patients with pre-collapse osteonecrosis of the femoral head. A pilot study of regenerative therapy using controlled release of recombinant human fibroblast growth factor for patients with pre-collapse osteonecrosis of the femoral head. Internat. Orthopaedics,40,8,1747-1754 Internat. Orthopaedics,40,8,1747-1754 Internat. Orthopaedics,40,8,1747-1754 2016/08 英語 研究論文(学術雑誌) 公開
Sato, Y., Mii, A., Hamazaki, Y., Fujita, H., Nakata, H., Masuda, K., Nishiyama, S., Shibuya, S., Haga, H., Ogawa, O., Shimizu, A., Narumiya, S., Kaisho, T., Arita, M., Yanagisawa, M., Miyasaka, M., Sharma, K., Minato, N., Kawamoto, H. and Yanagita, M. Sato, Y., Mii, A., Hamazaki, Y., Fujita, H., Nakata, H., Masuda, K., Nishiyama, S., Shibuya, S., Haga, H., Ogawa, O., Shimizu, A., Narumiya, S., Kaisho, T., Arita, M., Yanagisawa, M., Miyasaka, M., Sharma, K., Minato, N., Kawamoto, H. and Yanagita, M. Sato, Y., Mii, A., Hamazaki, Y., Fujita, H., Nakata, H., Masuda, K., Nishiyama, S., Shibuya, S., Haga, H., Ogawa, O., Shimizu, A., Narumiya, S., Kaisho, T., Arita, M., Yanagisawa, M., Miyasaka, M., Sharma, K., Minato, N., Kawamoto, H. and Yanagita, M. Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. JCI Insight,1,e87680 JCI Insight,1,e87680 JCI Insight,1,e87680 2016/07 公開
Kumagai M, Marui A, Tabata Y, Takeda T, Yamamoto M, Yonezawa A, Tanaka S, Yanagi S, Ito-Ihara T, Ikeda T, Murayama T, Teramukai S, Katsura T, Matsubara K, Kawakami K, Yokode M, Shimizu A, Sakata R Kumagai M, Marui A, Tabata Y, Takeda T, Yamamoto M, Yonezawa A, Tanaka S, Yanagi S, Ito-Ihara T, Ikeda T, Murayama T, Teramukai S, Katsura T, Matsubara K, Kawakami K, Yokode M, Shimizu A, Sakata R Kumagai M, Marui A, Tabata Y, Takeda T, Yamamoto M, Yonezawa A, Tanaka S, Yanagi S, Ito-Ihara T, Ikeda T, Murayama T, Teramukai S, Katsura T, Matsubara K, Kawakami K, Yokode M, Shimizu A, Sakata R Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia. Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia. Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia. Heart and vessels,31,5,721 Heart and vessels,31,5,721 Heart and vessels,31,5,721 2016/05 英語 研究論文(学術雑誌) 公開
Saito, K., Takahashi, K., Asahara, M., Kiso, H., Togo, Y., Tsukamoto, H., Huang, B., Sugai, M., Shimizu, A., Motokawa, M., Slavkin, H. C .and Bessho, K. Saito, K., Takahashi, K., Asahara, M., Kiso, H., Togo, Y., Tsukamoto, H., Huang, B., Sugai, M., Shimizu, A., Motokawa, M., Slavkin, H. C .and Bessho, K. Saito, K., Takahashi, K., Asahara, M., Kiso, H., Togo, Y., Tsukamoto, H., Huang, B., Sugai, M., Shimizu, A., Motokawa, M., Slavkin, H. C .and Bessho, K. Effects of Usag-1 and Bmp7 deficiencies on Murine Tooth Morphogenesis Effects of Usag-1 and Bmp7 deficiencies on Murine Tooth Morphogenesis Effects of Usag-1 and Bmp7 deficiencies on Murine Tooth Morphogenesis BMC Dev. Biol.,16,14 BMC Dev. Biol.,16,14 BMC Dev. Biol.,16,14 2016/05 英語 研究論文(学術雑誌) 公開
Hamanishi, J., Mandai, M., Ikeda, T., Minami, M., Kawaguchi, A., Murayama, T., Kanai, M., Mori, Y., Matsumoto, S., Chikuma, S., Matsumura, N., Abiko, K., Baba, T., Yamaguchi, K., Ueda, A., Hosoe, Y., Morita, S., Yokode, M., Shimizu, A., Honjo, T. and Konishi, I. Hamanishi, J., Mandai, M., Ikeda, T., Minami, M., Kawaguchi, A., Murayama, T., Kanai, M., Mori, Y., Matsumoto, S., Chikuma, S., Matsumura, N., Abiko, K., Baba, T., Yamaguchi, K., Ueda, A., Hosoe, Y., Morita, S., Yokode, M., Shimizu, A., Honjo, T. and Konishi, I. Hamanishi, J., Mandai, M., Ikeda, T., Minami, M., Kawaguchi, A., Murayama, T., Kanai, M., Mori, Y., Matsumoto, S., Chikuma, S., Matsumura, N., Abiko, K., Baba, T., Yamaguchi, K., Ueda, A., Hosoe, Y., Morita, S., Yokode, M., Shimizu, A., Honjo, T. and Konishi, I. Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer. Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer. Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer. Journal of Clinical Oncology,33,34,4015-4022 Journal of Clinical Oncology,33,34,4015-4022 Journal of Clinical Oncology,33,34,4015-4022 2015/12 英語 研究論文(学術雑誌) 公開
Huang B, Takahashi K, Goto T, Kiso H, Sugai M, Shimizu A, Kosugi S, Bessho K Huang B, Takahashi K, Goto T, Kiso H, Sugai M, Shimizu A, Kosugi S, Bessho K Huang B, Takahashi K, Goto T, Kiso H, Sugai M, Shimizu A, Kosugi S, Bessho K ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents. ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents. ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents. Journal of maxillofacial and oral surgery,14,2,247-251 Journal of maxillofacial and oral surgery,14,2,247-251 Journal of maxillofacial and oral surgery,14,2,247-251 2015/06 英語 研究論文(学術雑誌) 公開
Kim CJ, Hara E, Shimizu A, Sugai M, Kimura S Kim CJ, Hara E, Shimizu A, Sugai M, Kimura S Kim CJ, Hara E, Shimizu A, Sugai M, Kimura S Activation of B1a cells in peritoneal cavity by T cell-independent antigen expressed on polymeric micelle. Activation of B1a cells in peritoneal cavity by T cell-independent antigen expressed on polymeric micelle. Activation of B1a cells in peritoneal cavity by T cell-independent antigen expressed on polymeric micelle. Journal of pharmaceutical sciences,104,5,1839-1847 Journal of pharmaceutical sciences,104,5,1839-1847 Journal of pharmaceutical sciences,104,5,1839-1847 2015/05 公開
Jang KJ, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt SL, Igarashi K, Shimizu A, Sugai M Jang KJ, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt SL, Igarashi K, Shimizu A, Sugai M Jang KJ, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt SL, Igarashi K, Shimizu A, Sugai M Mitochondrial function provides instructive signals for activation-induced B-cell fates. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nature communications,6 Nature communications,6 Nature communications,6 2015/04 英語 研究論文(学術雑誌) 公開
Nakagawa T, Kumakawa K, Usami S, Hato N, Tabuchi K, Takahashi M, Fujiwara K, Sasaki A, Komune S, Sakamoto T, Hiraumi H, Yamamoto N, Tanaka S, Tada H, Yamamoto M, Yonezawa A, Ito-Ihara T, Ikeda T, Shimizu A, Tabata Y, Ito J Nakagawa T, Kumakawa K, Usami S, Hato N, Tabuchi K, Takahashi M, Fujiwara K, Sasaki A, Komune S, Sakamoto T, Hiraumi H, Yamamoto N, Tanaka S, Tada H, Yamamoto M, Yonezawa A, Ito-Ihara T, Ikeda T, Shimizu A, Tabata Y, Ito J Nakagawa T, Kumakawa K, Usami S, Hato N, Tabuchi K, Takahashi M, Fujiwara K, Sasaki A, Komune S, Sakamoto T, Hiraumi H, Yamamoto N, Tanaka S, Tada H, Yamamoto M, Yonezawa A, Ito-Ihara T, Ikeda T, Shimizu A, Tabata Y, Ito J A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment. A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment. A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment. BMC medicine,12,1 BMC medicine,12,1 BMC medicine,12,1 2014/11 英語 研究論文(学術雑誌) 公開
Sumi E, Sugie T, Yoshimura K, Tada H, Ikeda T, Suzuki E, Tanaka Y, Teramukai S, Shimizu A, Toi M, Minato N Sumi E, Sugie T, Yoshimura K, Tada H, Ikeda T, Suzuki E, Tanaka Y, Teramukai S, Shimizu A, Toi M, Minato N Sumi E, Sugie T, Yoshimura K, Tada H, Ikeda T, Suzuki E, Tanaka Y, Teramukai S, Shimizu A, Toi M, Minato N Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol. Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol. Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol. Journal of translational medicine,12,1 Journal of translational medicine,12,1 Journal of translational medicine,12,1 2014/11 英語 研究論文(学術雑誌) 公開
Huang B, Takahashi K, Jennings EA, Pumtang-On P, Kiso H, Togo Y, Saito K, Sugai M, Akira S, Shimizu A, Bessho K Huang B, Takahashi K, Jennings EA, Pumtang-On P, Kiso H, Togo Y, Saito K, Sugai M, Akira S, Shimizu A, Bessho K Huang B, Takahashi K, Jennings EA, Pumtang-On P, Kiso H, Togo Y, Saito K, Sugai M, Akira S, Shimizu A, Bessho K Prospective signs of cleidocranial dysplasia in Cebpb deficiency. Prospective signs of cleidocranial dysplasia in Cebpb deficiency. Prospective signs of cleidocranial dysplasia in Cebpb deficiency. Journal of biomedical science,21,1 Journal of biomedical science,21,1 Journal of biomedical science,21,1 2014/05 英語 研究論文(学術雑誌) 公開
Y. Naito-Matsui; S. Takada; Y. Kano; T. Iyoda; M. Sugai; A. Shimizu; K. Inaba; L. Nitschke; T. Tsubata; S. Oka; Y. Kozutsumi; H. Takematsu Y. Naito-Matsui; S. Takada; Y. Kano; T. Iyoda; M. Sugai; A. Shimizu; K. Inaba; L. Nitschke; T. Tsubata; S. Oka; Y. Kozutsumi; H. Takematsu Y. Naito-Matsui; S. Takada; Y. Kano; T. Iyoda; M. Sugai; A. Shimizu; K. Inaba; L. Nitschke; T. Tsubata; S. Oka; Y. Kozutsumi; H. Takematsu Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells Journal of Biological Chemistry,289,3,1564-1579 Journal of Biological Chemistry,289,3,1564-1579 Journal of Biological Chemistry,289,3,1564-1579 2014/01 英語 研究論文(学術雑誌) 公開
Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma. Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma. Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma. PloS one,9,8 PloS one,9,8 PloS one,9,8 2014 英語 研究論文(学術雑誌) 公開
Kiso H, Takahashi K, Saito K, Togo Y, Tsukamoto H, Huang B, Sugai M, Shimizu A, Tabata Y, Economides AN, Slavkin HC, Bessho K Kiso H, Takahashi K, Saito K, Togo Y, Tsukamoto H, Huang B, Sugai M, Shimizu A, Tabata Y, Economides AN, Slavkin HC, Bessho K Kiso H, Takahashi K, Saito K, Togo Y, Tsukamoto H, Huang B, Sugai M, Shimizu A, Tabata Y, Economides AN, Slavkin HC, Bessho K Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations. Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations. Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations. PloS one,9,5 PloS one,9,5 PloS one,9,5 2014 英語 研究論文(学術雑誌) 公開
Ariyasu H, Iwakura H, Yukawa N, Murayama T, Yokode M, Tada H, Yoshimura K, Teramukai S, Ito T, Shimizu A, Yonezawa A, Kangawa K, Mimori T, Akamizu T Ariyasu H, Iwakura H, Yukawa N, Murayama T, Yokode M, Tada H, Yoshimura K, Teramukai S, Ito T, Shimizu A, Yonezawa A, Kangawa K, Mimori T, Akamizu T Ariyasu H, Iwakura H, Yukawa N, Murayama T, Yokode M, Tada H, Yoshimura K, Teramukai S, Ito T, Shimizu A, Yonezawa A, Kangawa K, Mimori T, Akamizu T Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis. Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis. Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis. Endocrine journal,61,7,735-742 Endocrine journal,61,7,735-742 Endocrine journal,61,7,735-742 2014 英語 研究論文(学術雑誌) 公開
Morimoto N, Yoshimura K, Niimi M, Ito T, Aya R, Fujitaka J, Tada H, Teramukai S, Murayama T, Toyooka C, Miura K, Takemoto S, Kanda N, Kawai K, Yokode M, Shimizu A, Suzuki S Morimoto N, Yoshimura K, Niimi M, Ito T, Aya R, Fujitaka J, Tada H, Teramukai S, Murayama T, Toyooka C, Miura K, Takemoto S, Kanda N, Kawai K, Yokode M, Shimizu A, Suzuki S Morimoto N, Yoshimura K, Niimi M, Ito T, Aya R, Fujitaka J, Tada H, Teramukai S, Murayama T, Toyooka C, Miura K, Takemoto S, Kanda N, Kawai K, Yokode M, Shimizu A, Suzuki S Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers. Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers. Novel collagen/gelatin scaffold with sustained release of basic fibroblast growth factor: clinical trial for chronic skin ulcers. Tissue engineering. Part A,19,17-18,1931-1940 Tissue engineering. Part A,19,17-18,1931-1940 Tissue engineering. Part A,19,17-18,1931-1940 2013/09 英語 研究論文(学術雑誌) 公開
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T. Sugie; T. Sawada; N. Tagaya; T. Kinoshita; K. Yamagami; H. Suwa; T. Ikeda; K. Yoshimura; M. Niimi; A. Shimizu; M. Toi T. Sugie; T. Sawada; N. Tagaya; T. Kinoshita; K. Yamagami; H. Suwa; T. Ikeda; K. Yoshimura; M. Niimi; A. Shimizu; M. Toi T. Sugie; T. Sawada; N. Tagaya; T. Kinoshita; K. Yamagami; H. Suwa; T. Ikeda; K. Yoshimura; M. Niimi; A. Shimizu; M. Toi Comparison of the indocyanine green fluorescence and blue dye methods in detection of sentinel lymph nodes in early-stage breast cancer Comparison of the indocyanine green fluorescence and blue dye methods in detection of sentinel lymph nodes in early-stage breast cancer Comparison of the indocyanine green fluorescence and blue dye methods in detection of sentinel lymph nodes in early-stage breast cancer Annals of Surgical Oncology,20,7,2213-2218 Annals of Surgical Oncology,20,7,2213-2218 Annals of Surgical Oncology,20,7,2213-2218 2013/07 英語 研究論文(学術雑誌) 公開
B. Huang; K. Takahashi; T. Sakata-Goto; H. Kiso; Y. Togo; K. Saito; H. Tsukamoto; M. Sugai; S. Akira; A. Shimizu; K. Bessho B. Huang; K. Takahashi; T. Sakata-Goto; H. Kiso; Y. Togo; K. Saito; H. Tsukamoto; M. Sugai; S. Akira; A. Shimizu; K. Bessho B. Huang; K. Takahashi; T. Sakata-Goto; H. Kiso; Y. Togo; K. Saito; H. Tsukamoto; M. Sugai; S. Akira; A. Shimizu; K. Bessho Phenotypes of CCAAT/enhancer-binding protein beta deficiency: Hyperdontia and elongated coronoid process Phenotypes of CCAAT/enhancer-binding protein beta deficiency: Hyperdontia and elongated coronoid process Phenotypes of CCAAT/enhancer-binding protein beta deficiency: Hyperdontia and elongated coronoid process Oral Diseases,19,2,144-150 Oral Diseases,19,2,144-150 Oral Diseases,19,2,144-150 2013 英語 研究論文(学術雑誌) 公開
T. Sakata-Goto; K. Takahashi; H. Kiso; B. Huang; H. Tsukamoto; M. Takemoto; T. Hayashi; M. Sugai; T. Nakamura; Y. Yokota; A. Shimizu; H. Slavkin; K. Bessho T. Sakata-Goto; K. Takahashi; H. Kiso; B. Huang; H. Tsukamoto; M. Takemoto; T. Hayashi; M. Sugai; T. Nakamura; Y. Yokota; A. Shimizu; H. Slavkin; K. Bessho T. Sakata-Goto; K. Takahashi; H. Kiso; B. Huang; H. Tsukamoto; M. Takemoto; T. Hayashi; M. Sugai; T. Nakamura; Y. Yokota; A. Shimizu; H. Slavkin; K. Bessho Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis Bone,50,1,69-78 Bone,50,1,69-78 Bone,50,1,69-78 2012/01 英語 研究論文(学術雑誌) 公開
N. Morimoto; K. Yoshimura; M. Niimi; T. Ito; H. Tada; S. Teramukai; T. Murayama; C. Toyooka; S. Takemoto; K. Kawai; M. Yokode; A. Shimizu; S. Suzuki N. Morimoto; K. Yoshimura; M. Niimi; T. Ito; H. Tada; S. Teramukai; T. Murayama; C. Toyooka; S. Takemoto; K. Kawai; M. Yokode; A. Shimizu; S. Suzuki N. Morimoto; K. Yoshimura; M. Niimi; T. Ito; H. Tada; S. Teramukai; T. Murayama; C. Toyooka; S. Takemoto; K. Kawai; M. Yokode; A. Shimizu; S. Suzuki An exploratory clinical trial for combination wound therapy with a novel medical matrix and fibroblast growth factor in patients with chronic skin ulcers: A study protocol An exploratory clinical trial for combination wound therapy with a novel medical matrix and fibroblast growth factor in patients with chronic skin ulcers: A study protocol An exploratory clinical trial for combination wound therapy with a novel medical matrix and fibroblast growth factor in patients with chronic skin ulcers: A study protocol American Journal of Translational Research,4,1,52-59 American Journal of Translational Research,4,1,52-59 American Journal of Translational Research,4,1,52-59 2012 英語 研究論文(学術雑誌) 公開
Y. Nambu; T. Hayashi; K.-J. Jang; K. Aoki; H. Mano; K. Nakano; M. Osato; K. Takahashi; K. Itoh; S. Teramukai; T. Komori; J. Fujita; Y. Ito; A. Shimizu; M. Sugai Y. Nambu; T. Hayashi; K.-J. Jang; K. Aoki; H. Mano; K. Nakano; M. Osato; K. Takahashi; K. Itoh; S. Teramukai; T. Komori; J. Fujita; Y. Ito; A. Shimizu; M. Sugai Y. Nambu; T. Hayashi; K.-J. Jang; K. Aoki; H. Mano; K. Nakano; M. Osato; K. Takahashi; K. Itoh; S. Teramukai; T. Komori; J. Fujita; Y. Ito; A. Shimizu; M. Sugai In situ differentiation of CD8α αt cells from CD4 T cells in peripheral lymphoid tissues In situ differentiation of CD8α αt cells from CD4 T cells in peripheral lymphoid tissues In situ differentiation of CD8α αt cells from CD4 T cells in peripheral lymphoid tissues Scientific Reports,2 Scientific Reports,2 Scientific Reports,2 2012 英語 公開
B. Huang; K. Takahashi; T. Sakata; H. Kiso; M. Sugai; K. Fujimura; A. Shimizu; S. Kosugi; T. Sato; K. Bessho B. Huang; K. Takahashi; T. Sakata; H. Kiso; M. Sugai; K. Fujimura; A. Shimizu; S. Kosugi; T. Sato; K. Bessho B. Huang; K. Takahashi; T. Sakata; H. Kiso; M. Sugai; K. Fujimura; A. Shimizu; S. Kosugi; T. Sato; K. Bessho Increased risk of temporomandibular joint closed lock: A case-control study of ANKH polymorphisms Increased risk of temporomandibular joint closed lock: A case-control study of ANKH polymorphisms Increased risk of temporomandibular joint closed lock: A case-control study of ANKH polymorphisms PLoS ONE,6,10 PLoS ONE,6,10 PLoS ONE,6,10 2011/10 英語 研究論文(学術雑誌) 公開
S. Fujibayashi; M. Takemoto; M. Neo; T. Matsushita; T. Kokubo; K. Doi; T. Ito; A. Shimizu; T. Nakamura S. Fujibayashi; M. Takemoto; M. Neo; T. Matsushita; T. Kokubo; K. Doi; T. Ito; A. Shimizu; T. Nakamura S. Fujibayashi; M. Takemoto; M. Neo; T. Matsushita; T. Kokubo; K. Doi; T. Ito; A. Shimizu; T. Nakamura A novel synthetic material for spinal fusion: A prospective clinical trial of porous bioactive titanium metal for lumbar interbody fusion A novel synthetic material for spinal fusion: A prospective clinical trial of porous bioactive titanium metal for lumbar interbody fusion A novel synthetic material for spinal fusion: A prospective clinical trial of porous bioactive titanium metal for lumbar interbody fusion European Spine Journal,20,9,1486-1495 European Spine Journal,20,9,1486-1495 European Spine Journal,20,9,1486-1495 2011/09 英語 研究論文(学術雑誌) 公開
M. Sugai; K. Aoki; M. Osato; Y. Nambu; K. Ito; M.M. Taketo; A. Shimizu M. Sugai; K. Aoki; M. Osato; Y. Nambu; K. Ito; M.M. Taketo; A. Shimizu M. Sugai; K. Aoki; M. Osato; Y. Nambu; K. Ito; M.M. Taketo; A. Shimizu Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation Journal of Immunology,186,11,6515-6520 Journal of Immunology,186,11,6515-6520 Journal of Immunology,186,11,6515-6520 2011/06 英語 研究論文(学術雑誌) 公開
A. Ido; A. Moriuchi; M. Numata; T. Murayama; S. Teramukai; H. Marusawa; N. Yamaji; H. Setoyama; I. Kim; T. Chiba; S. Higuchi; M. Yokode; M. Fukushima; A. Shimizu; H. Tsubouchi A. Ido; A. Moriuchi; M. Numata; T. Murayama; S. Teramukai; H. Marusawa; N. Yamaji; H. Setoyama; I. Kim; T. Chiba; S. Higuchi; M. Yokode; M. Fukushima; A. Shimizu; H. Tsubouchi A. Ido; A. Moriuchi; M. Numata; T. Murayama; S. Teramukai; H. Marusawa; N. Yamaji; H. Setoyama; I. Kim; T. Chiba; S. Higuchi; M. Yokode; M. Fukushima; A. Shimizu; H. Tsubouchi Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: A phase I/II clinical trial, following preclinical studies to ensure safety Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: A phase I/II clinical trial, following preclinical studies to ensure safety Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: A phase I/II clinical trial, following preclinical studies to ensure safety Journal of Translational Medicine,9 Journal of Translational Medicine,9 Journal of Translational Medicine,9 2011/05 英語 研究論文(学術雑誌) 公開
T. Kitawaki; N. Kadowaki; K. Fukunaga; Y. Kasai; T. Maekawa; K. Ohmori; T. Itoh; A. Shimizu; K. Kuzushima; T. Kondo; T. Ishikawa; T. Uchiyama T. Kitawaki; N. Kadowaki; K. Fukunaga; Y. Kasai; T. Maekawa; K. Ohmori; T. Itoh; A. Shimizu; K. Kuzushima; T. Kondo; T. Ishikawa; T. Uchiyama T. Kitawaki; N. Kadowaki; K. Fukunaga; Y. Kasai; T. Maekawa; K. Ohmori; T. Itoh; A. Shimizu; K. Kuzushima; T. Kondo; T. Ishikawa; T. Uchiyama Cross-priming of CD8<sup>+</sup> T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia Cross-priming of CD8<sup>+</sup> T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia Cross-priming of CD8<sup>+</sup> T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia Experimental Hematology,39,4,424-433 Experimental Hematology,39,4,424-433 Experimental Hematology,39,4,424-433 2011/04 英語 研究論文(学術雑誌) 公開
M. Sugai; K. Watanabe; Y. Nambu; T. Hayashi; A. Shimizu M. Sugai; K. Watanabe; Y. Nambu; T. Hayashi; A. Shimizu M. Sugai; K. Watanabe; Y. Nambu; T. Hayashi; A. Shimizu Functions of Runx in IgA class switch recombination Functions of Runx in IgA class switch recombination Functions of Runx in IgA class switch recombination Journal of Cellular Biochemistry,112,2,409-414 Journal of Cellular Biochemistry,112,2,409-414 Journal of Cellular Biochemistry,112,2,409-414 2011 英語 研究論文(学術雑誌) 公開
S. Tanaka; S. Maeda; M. Hashimoto; C. Fujimori; Y. Ito; S. Teradaira; K. Hirota; H. Yoshitomi; T. Katakai; A. Shimizu; T. Nomura; N. Sakaguchi; S. Sakaguchi S. Tanaka; S. Maeda; M. Hashimoto; C. Fujimori; Y. Ito; S. Teradaira; K. Hirota; H. Yoshitomi; T. Katakai; A. Shimizu; T. Nomura; N. Sakaguchi; S. Sakaguchi S. Tanaka; S. Maeda; M. Hashimoto; C. Fujimori; Y. Ito; S. Teradaira; K. Hirota; H. Yoshitomi; T. Katakai; A. Shimizu; T. Nomura; N. Sakaguchi; S. Sakaguchi Graded attenuation of TCR Signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function Graded attenuation of TCR Signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function Graded attenuation of TCR Signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function Journal of Immunology,185,4,2295-2305 Journal of Immunology,185,4,2295-2305 Journal of Immunology,185,4,2295-2305 2010/08 英語 研究論文(学術雑誌) 公開
K. Watanabe; M. Sugai; Y. Nambu; M. Osato; T. Hayashi; M. Kawaguchi; T. Komori; Y. Ito; A. Shimizu K. Watanabe; M. Sugai; Y. Nambu; M. Osato; T. Hayashi; M. Kawaguchi; T. Komori; Y. Ito; A. Shimizu K. Watanabe; M. Sugai; Y. Nambu; M. Osato; T. Hayashi; M. Kawaguchi; T. Komori; Y. Ito; A. Shimizu Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling Journal of Immunology,184,6,2785-2792 Journal of Immunology,184,6,2785-2792 Journal of Immunology,184,6,2785-2792 2010/03 英語 研究論文(学術雑誌) 公開
H. Suto; T. Katakai; M. Sugai; T. Kinashi; A. Shimizu H. Suto; T. Katakai; M. Sugai; T. Kinashi; A. Shimizu H. Suto; T. Katakai; M. Sugai; T. Kinashi; A. Shimizu CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways International Immunology,21,4,467-476 International Immunology,21,4,467-476 International Immunology,21,4,467-476 2009/04 英語 研究論文(学術雑誌) 公開
M. Onoue; T. Terada; M. Kobayashi; T. Katsura; S. Matsumoto; K. Yanagihara; T. Nishimura; M. Kanai; S. Teramukai; A. Shimizu; M. Fukushima; K.-I. Inui M. Onoue; T. Terada; M. Kobayashi; T. Katsura; S. Matsumoto; K. Yanagihara; T. Nishimura; M. Kanai; S. Teramukai; A. Shimizu; M. Fukushima; K.-I. Inui M. Onoue; T. Terada; M. Kobayashi; T. Katsura; S. Matsumoto; K. Yanagihara; T. Nishimura; M. Kanai; S. Teramukai; A. Shimizu; M. Fukushima; K.-I. Inui UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients International Journal of Clinical Oncology,14,2,136-142 International Journal of Clinical Oncology,14,2,136-142 International Journal of Clinical Oncology,14,2,136-142 2009/04 英語 研究論文(学術雑誌) 公開
T. Katakai; H. Suto; M. Sugai; H. Gonda; A. Togawa; S. Suematsu; Y. Ebisuno; K. Katagiri; T. Kinashi; A. Shimizu T. Katakai; H. Suto; M. Sugai; H. Gonda; A. Togawa; S. Suematsu; Y. Ebisuno; K. Katagiri; T. Kinashi; A. Shimizu T. Katakai; H. Suto; M. Sugai; H. Gonda; A. Togawa; S. Suematsu; Y. Ebisuno; K. Katagiri; T. Kinashi; A. Shimizu Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs Journal of Immunology,181,9,6189-6200 Journal of Immunology,181,9,6189-6200 Journal of Immunology,181,9,6189-6200 2008/11 英語 研究論文(学術雑誌) 公開
A. Murashima-Suginami; K. Takahashi; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho A. Murashima-Suginami; K. Takahashi; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho A. Murashima-Suginami; K. Takahashi; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse Biochemical and Biophysical Research Communications,369,4,1012-1016 Biochemical and Biophysical Research Communications,369,4,1012-1016 Biochemical and Biophysical Research Communications,369,4,1012-1016 2008/05 英語 研究論文(学術雑誌) 公開
T. Akamizu; H. Iwakura; H. Ariyasu; H. Hosoda; T. Murayama; M. Yokode; S. Teramukai; H. Seno; T. Chiba; S. Noma; Y. Nakai; M. Fukunaga; Y. Nakai; K. Kangawa; T. Irako; H. Tada; I. Bando; K. Miura; A. Matsuyama; A. Shimizu; M. Fukushima; K. Shide; Y. Tamai; N. Watanabe; H. Nakase; T. Abe; T. Shinomiya; A. Fukao; M. Suda T. Akamizu; H. Iwakura; H. Ariyasu; H. Hosoda; T. Murayama; M. Yokode; S. Teramukai; H. Seno; T. Chiba; S. Noma; Y. Nakai; M. Fukunaga; Y. Nakai; K. Kangawa; T. Irako; H. Tada; I. Bando; K. Miura; A. Matsuyama; A. Shimizu; M. Fukushima; K. Shide; Y. Tamai; N. Watanabe; H. Nakase; T. Abe; T. Shinomiya; A. Fukao; M. Suda T. Akamizu; H. Iwakura; H. Ariyasu; H. Hosoda; T. Murayama; M. Yokode; S. Teramukai; H. Seno; T. Chiba; S. Noma; Y. Nakai; M. Fukunaga; Y. Nakai; K. Kangawa; T. Irako; H. Tada; I. Bando; K. Miura; A. Matsuyama; A. Shimizu; M. Fukushima; K. Shide; Y. Tamai; N. Watanabe; H. Nakase; T. Abe; T. Shinomiya; A. Fukao; M. Suda Repeated administration of ghrelin to patients with functional dyspepsia: Its effects on food intake and appetite Repeated administration of ghrelin to patients with functional dyspepsia: Its effects on food intake and appetite Repeated administration of ghrelin to patients with functional dyspepsia: Its effects on food intake and appetite European Journal of Endocrinology,158,4,491-498 European Journal of Endocrinology,158,4,491-498 European Journal of Endocrinology,158,4,491-498 2008/04 英語 研究論文(学術雑誌) 公開
T. Katakai; A. Shimizu T. Katakai; A. Shimizu T. Katakai; A. Shimizu Undesired meeting of lymphocytes: Organ-specific infiltration and the organization of ectopic lymphoid tissue in a murine experimental autoimmune gastritis Undesired meeting of lymphocytes: Organ-specific infiltration and the organization of ectopic lymphoid tissue in a murine experimental autoimmune gastritis Undesired meeting of lymphocytes: Organ-specific infiltration and the organization of ectopic lymphoid tissue in a murine experimental autoimmune gastritis Immunology Letters,118,2,103-109 Immunology Letters,118,2,103-109 Immunology Letters,118,2,103-109 2008 英語 研究論文(学術雑誌) 公開
T. Kishida; Y. Hiromura; M. Shin-Ya; H. Asada; H. Kuriyama; M. Sugai; A. Shimizu; Y. Yokota; T. Hama; J. Imanishi; Y. Hisa; O. Mazda T. Kishida; Y. Hiromura; M. Shin-Ya; H. Asada; H. Kuriyama; M. Sugai; A. Shimizu; Y. Yokota; T. Hama; J. Imanishi; Y. Hisa; O. Mazda T. Kishida; Y. Hiromura; M. Shin-Ya; H. Asada; H. Kuriyama; M. Sugai; A. Shimizu; Y. Yokota; T. Hama; J. Imanishi; Y. Hisa; O. Mazda IL-21 induces inhibitor of differentiation 2 and leads to complete abrogation of anaphylaxis in mice IL-21 induces inhibitor of differentiation 2 and leads to complete abrogation of anaphylaxis in mice IL-21 induces inhibitor of differentiation 2 and leads to complete abrogation of anaphylaxis in mice Journal of Immunology,179,12,8554-8561 Journal of Immunology,179,12,8554-8561 Journal of Immunology,179,12,8554-8561 2007/12 英語 研究論文(学術雑誌) 公開
A. Murashima-Suginami; K. Takahashi; T. Kawabata; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho A. Murashima-Suginami; K. Takahashi; T. Kawabata; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho A. Murashima-Suginami; K. Takahashi; T. Kawabata; T. Sakata; H. Tsukamoto; M. Sugai; M. Yanagita; A. Shimizu; T. Sakurai; H.C. Slavkin; K. Bessho Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation Biochemical and Biophysical Research Communications,359,3,549-555 Biochemical and Biophysical Research Communications,359,3,549-555 Biochemical and Biophysical Research Communications,359,3,549-555 2007/08 英語 研究論文(学術雑誌) 公開
T. Katakai; A. Shimizu T. Katakai; A. Shimizu T. Katakai; A. Shimizu The network of fibroblastic reticular cells in the lymph node: Functional framework for immune surveillance The network of fibroblastic reticular cells in the lymph node: Functional framework for immune surveillance The network of fibroblastic reticular cells in the lymph node: Functional framework for immune surveillance Current Immunology Reviews,3,4,251-257 Current Immunology Reviews,3,4,251-257 Current Immunology Reviews,3,4,251-257 2007 英語 研究論文(学術雑誌) 公開
T. Katakai; T. Nomura; H. Gonda; M. Sugai; Y. Agata; A. Nishio; T. Masuda; S. Sakaguchi; A. Shimizu T. Katakai; T. Nomura; H. Gonda; M. Sugai; Y. Agata; A. Nishio; T. Masuda; S. Sakaguchi; A. Shimizu T. Katakai; T. Nomura; H. Gonda; M. Sugai; Y. Agata; A. Nishio; T. Masuda; S. Sakaguchi; A. Shimizu Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H<sup>+</sup>/K<sup>+</sup>-ATPase-reactive TCR transgenic mouse Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H<sup>+</sup>/K<sup>+</sup>-ATPase-reactive TCR transgenic mouse Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H<sup>+</sup>/K<sup>+</sup>-ATPase-reactive TCR transgenic mouse Journal of Immunology,177,11,7858-7867 Journal of Immunology,177,11,7858-7867 Journal of Immunology,177,11,7858-7867 2006/12 英語 研究論文(学術雑誌) 公開
T. Kubo; T. Wada; Y. Yamaguchi; A. Shimizu; H. Handa T. Kubo; T. Wada; Y. Yamaguchi; A. Shimizu; H. Handa T. Kubo; T. Wada; Y. Yamaguchi; A. Shimizu; H. Handa Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs Nucleic Acids Research,34,21,6264-6271 Nucleic Acids Research,34,21,6264-6271 Nucleic Acids Research,34,21,6264-6271 2006/12 英語 研究論文(学術雑誌) 公開
T. Hara; T. Katakai; J.-H. Lee; Y. Nambu; N. Nakajima-Nagata; H. Gonda; M. Sugai; A. Shimizu T. Hara; T. Katakai; J.-H. Lee; Y. Nambu; N. Nakajima-Nagata; H. Gonda; M. Sugai; A. Shimizu T. Hara; T. Katakai; J.-H. Lee; Y. Nambu; N. Nakajima-Nagata; H. Gonda; M. Sugai; A. Shimizu A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion A transmembrane chemokine, CXC chemokine ligand 16, expressed by lymph node fibroblastic reticular cells has the potential to regulate T cell migration and adhesion International Immunology,18,2,301-311 International Immunology,18,2,301-311 International Immunology,18,2,301-311 2006/02 英語 研究論文(学術雑誌) 公開
T. Akamizu; T. Murayama; S. Teramukai; K. Miura; I. Bando; T. Irako; H. Iwakura; H. Ariyasu; H. Hosoda; H. Tada; A. Matsuyama; S. Kojima; T. Wada; Y. Wakatsuki; K. Matsubayashi; T. Kawakita; A. Shimizu; M. Fukushima; M. Yokode; K. Kangawa T. Akamizu; T. Murayama; S. Teramukai; K. Miura; I. Bando; T. Irako; H. Iwakura; H. Ariyasu; H. Hosoda; H. Tada; A. Matsuyama; S. Kojima; T. Wada; Y. Wakatsuki; K. Matsubayashi; T. Kawakita; A. Shimizu; M. Fukushima; M. Yokode; K. Kangawa T. Akamizu; T. Murayama; S. Teramukai; K. Miura; I. Bando; T. Irako; H. Iwakura; H. Ariyasu; H. Hosoda; H. Tada; A. Matsuyama; S. Kojima; T. Wada; Y. Wakatsuki; K. Matsubayashi; T. Kawakita; A. Shimizu; M. Fukushima; M. Yokode; K. Kangawa Plasma ghrelin levels in healthy elderly volunteers: The levels acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure Plasma ghrelin levels in healthy elderly volunteers: The levels acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure Plasma ghrelin levels in healthy elderly volunteers: The levels acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure Journal of Endocrinology,188,2,333-344 Journal of Endocrinology,188,2,333-344 Journal of Endocrinology,188,2,333-344 2006/02 英語 研究論文(学術雑誌) 公開
Y. Itokazu; M. Kitada; M. Dezawa; A. Mizoguchi; N. Matsumoto; A. Shimizu; C. Ide Y. Itokazu; M. Kitada; M. Dezawa; A. Mizoguchi; N. Matsumoto; A. Shimizu; C. Ide Y. Itokazu; M. Kitada; M. Dezawa; A. Mizoguchi; N. Matsumoto; A. Shimizu; C. Ide Choroid plexus ependymal cells host neural progenitor cells in the rat Choroid plexus ependymal cells host neural progenitor cells in the rat Choroid plexus ependymal cells host neural progenitor cells in the rat GLIA,53,1,32-42 GLIA,53,1,32-42 GLIA,53,1,32-42 2006/01 英語 研究論文(学術雑誌) 公開
T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-β type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-β type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-β type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds Journal of Controlled Release,110,3,610-617 Journal of Controlled Release,110,3,610-617 Journal of Controlled Release,110,3,610-617 2006 英語 研究論文(学術雑誌) 公開
T. Kawabata; K. Takahashi; M. Sugai; A. Murashima-Suginami; S. Ando; A. Shimizu; S. Kosugi; T. Sato; M. Nishida; K. Murakami; T. Iizuka T. Kawabata; K. Takahashi; M. Sugai; A. Murashima-Suginami; S. Ando; A. Shimizu; S. Kosugi; T. Sato; M. Nishida; K. Murakami; T. Iizuka T. Kawabata; K. Takahashi; M. Sugai; A. Murashima-Suginami; S. Ando; A. Shimizu; S. Kosugi; T. Sato; M. Nishida; K. Murakami; T. Iizuka Polymorphisms in PTCH1 affect the risk of ameloblastoma Polymorphisms in PTCH1 affect the risk of ameloblastoma Polymorphisms in PTCH1 affect the risk of ameloblastoma Journal of Dental Research,84,9,812-816 Journal of Dental Research,84,9,812-816 Journal of Dental Research,84,9,812-816 2005/09 英語 研究論文(学術雑誌) 公開
H. Hiratani; D.W. Bowden; S. Ikegami; S. Shirasawa; A. Shimizu; Y. Iwatani; T. Akamizu H. Hiratani; D.W. Bowden; S. Ikegami; S. Shirasawa; A. Shimizu; Y. Iwatani; T. Akamizu H. Hiratani; D.W. Bowden; S. Ikegami; S. Shirasawa; A. Shimizu; Y. Iwatani; T. Akamizu Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves\\' disease Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves\\' disease Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves\\' disease Journal of Clinical Endocrinology and Metabolism,90,5,2898-2903 Journal of Clinical Endocrinology and Metabolism,90,5,2898-2903 Journal of Clinical Endocrinology and Metabolism,90,5,2898-2903 2005/05 英語 研究論文(学術雑誌) 公開
T. Kusunoki; M. Sugai; H. Gonda; Y. Nambu; N. Nagata-Nakajima; T. Katakai; M. Kusunoki; A. Sakamoto; T. Tokuhisa; T. Nakahata; Y. Yokota; A. Shimizu T. Kusunoki; M. Sugai; H. Gonda; Y. Nambu; N. Nagata-Nakajima; T. Katakai; M. Kusunoki; A. Sakamoto; T. Tokuhisa; T. Nakahata; Y. Yokota; A. Shimizu T. Kusunoki; M. Sugai; H. Gonda; Y. Nambu; N. Nagata-Nakajima; T. Katakai; M. Kusunoki; A. Sakamoto; T. Tokuhisa; T. Nakahata; Y. Yokota; A. Shimizu CpG inhibits IgE class switch recombination through suppression of NFκB activity, but not through Id2 or Bcl6 CpG inhibits IgE class switch recombination through suppression of NFκB activity, but not through Id2 or Bcl6 CpG inhibits IgE class switch recombination through suppression of NFκB activity, but not through Id2 or Bcl6 Biochemical and Biophysical Research Communications,328,2,499-506 Biochemical and Biophysical Research Communications,328,2,499-506 Biochemical and Biophysical Research Communications,328,2,499-506 2005/03 英語 研究論文(学術雑誌) 公開
T. Kusunoki; I. Okafuji; T. Yoshioka; M. Saito; R. Nishikomori; T. Heike; M. Sugai; A. Shimizu; T. Nakahata T. Kusunoki; I. Okafuji; T. Yoshioka; M. Saito; R. Nishikomori; T. Heike; M. Sugai; A. Shimizu; T. Nakahata T. Kusunoki; I. Okafuji; T. Yoshioka; M. Saito; R. Nishikomori; T. Heike; M. Sugai; A. Shimizu; T. Nakahata SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis [5] SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis [5] SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis [5] Journal of Allergy and Clinical Immunology,115,3,636-638 Journal of Allergy and Clinical Immunology,115,3,636-638 Journal of Allergy and Clinical Immunology,115,3,636-638 2005/03 英語 研究論文(学術雑誌) 公開
T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata Delivery of plasmid DNA expressing small interference RNA for TGF-β type II receptor by cationized gelatin to prevent interstitial renal fibrosis Delivery of plasmid DNA expressing small interference RNA for TGF-β type II receptor by cationized gelatin to prevent interstitial renal fibrosis Delivery of plasmid DNA expressing small interference RNA for TGF-β type II receptor by cationized gelatin to prevent interstitial renal fibrosis Journal of Controlled Release,105,3,318-331 Journal of Controlled Release,105,3,318-331 Journal of Controlled Release,105,3,318-331 2005 英語 研究論文(学術雑誌) 公開
T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nagata-Nakajima; M. Sugai; A. Shimizu; Y. Tabata Targeting of plasmid DNA to renal interstitial fibroblasts by cationized gelatin Targeting of plasmid DNA to renal interstitial fibroblasts by cationized gelatin Targeting of plasmid DNA to renal interstitial fibroblasts by cationized gelatin Biological and Pharmaceutical Bulletin,28,10,2007-2010 Biological and Pharmaceutical Bulletin,28,10,2007-2010 Biological and Pharmaceutical Bulletin,28,10,2007-2010 2005 英語 研究論文(学術雑誌) 公開
T. Kushibiki; N. Nakajima-Nagata; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nakajima-Nagata; M. Sugai; A. Shimizu; Y. Tabata T. Kushibiki; N. Nakajima-Nagata; M. Sugai; A. Shimizu; Y. Tabata Delivery of small interference RNA to renal interstitial fibroblasts by cationized gelatin Delivery of small interference RNA to renal interstitial fibroblasts by cationized gelatin Delivery of small interference RNA to renal interstitial fibroblasts by cationized gelatin Polymer Preprints, Japan,54,1,2143- Polymer Preprints, Japan,54,1,2143- Polymer Preprints, Japan,54,1,2143- 2005 英語 研究論文(学術雑誌) 公開
J.-H. Lee; T. Katakai; T. Hara; H. Gonda; M. Sugai; A. Shimizu J.-H. Lee; T. Katakai; T. Hara; H. Gonda; M. Sugai; A. Shimizu J.-H. Lee; T. Katakai; T. Hara; H. Gonda; M. Sugai; A. Shimizu Roles of p-ERM and Rho-ROCK signalling in lymphocyte polarity and uropod formation Roles of p-ERM and Rho-ROCK signalling in lymphocyte polarity and uropod formation Roles of p-ERM and Rho-ROCK signalling in lymphocyte polarity and uropod formation Journal of Cell Biology,167,2,327-337 Journal of Cell Biology,167,2,327-337 Journal of Cell Biology,167,2,327-337 2004/10 英語 研究論文(学術雑誌) 公開
T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes Journal of Experimental Medicine,200,6,783-795 Journal of Experimental Medicine,200,6,783-795 Journal of Experimental Medicine,200,6,783-795 2004/09 英語 研究論文(学術雑誌) 公開
T. Akamizu; K. Takaya; T. Irako; H. Hosoda; S. Teramukai; A. Matsuyama; H. Tada; K. Miura; A. Shimizu; M. Fukushima; M. Yokode; K. Tanaka; K. Kangawa T. Akamizu; K. Takaya; T. Irako; H. Hosoda; S. Teramukai; A. Matsuyama; H. Tada; K. Miura; A. Shimizu; M. Fukushima; M. Yokode; K. Tanaka; K. Kangawa T. Akamizu; K. Takaya; T. Irako; H. Hosoda; S. Teramukai; A. Matsuyama; H. Tada; K. Miura; A. Shimizu; M. Fukushima; M. Yokode; K. Tanaka; K. Kangawa Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects European Journal of Endocrinology,150,4,447-455 European Journal of Endocrinology,150,4,447-455 European Journal of Endocrinology,150,4,447-455 2004/04 英語 研究論文(学術雑誌) 公開
N. Nakajima-Nagata; M. Sugai; T. Sakurai; J.-I. Miyazaki; Y. Tabata; A. Shimizu N. Nakajima-Nagata; M. Sugai; T. Sakurai; J.-I. Miyazaki; Y. Tabata; A. Shimizu N. Nakajima-Nagata; M. Sugai; T. Sakurai; J.-I. Miyazaki; Y. Tabata; A. Shimizu Pdx-1 enables insulin secretion by regulating synaptotagmin 1 gene expression Pdx-1 enables insulin secretion by regulating synaptotagmin 1 gene expression Pdx-1 enables insulin secretion by regulating synaptotagmin 1 gene expression Biochemical and Biophysical Research Communications,318,3,631-635 Biochemical and Biophysical Research Communications,318,3,631-635 Biochemical and Biophysical Research Communications,318,3,631-635 2004 英語 研究論文(学術雑誌) 公開
N. Nakajima-Nagata; T. Sakurai; T. Mitaka; T. Katakai; E. Yamato; J.-I. Miyazaki; Y. Tabata; M. Sugai; A. Shimizu N. Nakajima-Nagata; T. Sakurai; T. Mitaka; T. Katakai; E. Yamato; J.-I. Miyazaki; Y. Tabata; M. Sugai; A. Shimizu N. Nakajima-Nagata; T. Sakurai; T. Mitaka; T. Katakai; E. Yamato; J.-I. Miyazaki; Y. Tabata; M. Sugai; A. Shimizu In vitro induction of adult hepatic progenitor cells into insulin-producing cells In vitro induction of adult hepatic progenitor cells into insulin-producing cells In vitro induction of adult hepatic progenitor cells into insulin-producing cells Biochemical and Biophysical Research Communications,318,3,625-630 Biochemical and Biophysical Research Communications,318,3,625-630 Biochemical and Biophysical Research Communications,318,3,625-630 2004 英語 研究論文(学術雑誌) 公開
Y. Bando; A. Shimizu; C. Ra Y. Bando; A. Shimizu; C. Ra Y. Bando; A. Shimizu; C. Ra Characterization of V<sub>Hε</sub> gene expressed in PBL from children with atopic diseases: Detection of homologous V<sub>H</sub>1-69 derived transcripts from three unrelated patients Characterization of V<sub>Hε</sub> gene expressed in PBL from children with atopic diseases: Detection of homologous V<sub>H</sub>1-69 derived transcripts from three unrelated patients Characterization of V<sub>Hε</sub> gene expressed in PBL from children with atopic diseases: Detection of homologous V<sub>H</sub>1-69 derived transcripts from three unrelated patients Immunology Letters,94,1-2,99-106 Immunology Letters,94,1-2,99-106 Immunology Letters,94,1-2,99-106 2004 英語 研究論文(学術雑誌) 公開
T. Katakai; T. Hara; J.-H. Lee; H. Gonda; M. Sugai; A. Shimizu T. Katakai; T. Hara; J.-H. Lee; H. Gonda; M. Sugai; A. Shimizu T. Katakai; T. Hara; J.-H. Lee; H. Gonda; M. Sugai; A. Shimizu A novel reticular stromal structure in lymph node cortex: An immuno-platform for interactions among dendritic cells, T cells and B cells A novel reticular stromal structure in lymph node cortex: An immuno-platform for interactions among dendritic cells, T cells and B cells A novel reticular stromal structure in lymph node cortex: An immuno-platform for interactions among dendritic cells, T cells and B cells International Immunology,16,8,1133-1142 International Immunology,16,8,1133-1142 International Immunology,16,8,1133-1142 2004 英語 研究論文(学術雑誌) 公開
M. Sugai; H. Gonda; Y. Nambu; Y. Yokota; A. Shimizu M. Sugai; H. Gonda; Y. Nambu; Y. Yokota; A. Shimizu M. Sugai; H. Gonda; Y. Nambu; Y. Yokota; A. Shimizu Role of Id proteins in B lymphocyte activation: New insights from knockout mouse studies Role of Id proteins in B lymphocyte activation: New insights from knockout mouse studies Role of Id proteins in B lymphocyte activation: New insights from knockout mouse studies Journal of Molecular Medicine,82,9,592-599 Journal of Molecular Medicine,82,9,592-599 Journal of Molecular Medicine,82,9,592-599 2004 英語 研究論文(学術雑誌) 公開
T. Katakai; A. Shimizu T. Katakai; A. Shimizu T. Katakai; A. Shimizu Chemokines and autoimmune diseases Chemokines and autoimmune diseases Chemokines and autoimmune diseases Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents,3,4,341-350 Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents,3,4,341-350 Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents,3,4,341-350 2004 英語 研究論文(学術雑誌) 公開
Y. Nambu; M. Sugai; H. Gonda; C.-G. Lee; T. Katakai; Y. Agata; Y. Yokota; A. Shimizu Y. Nambu; M. Sugai; H. Gonda; C.-G. Lee; T. Katakai; Y. Agata; Y. Yokota; A. Shimizu Y. Nambu; M. Sugai; H. Gonda; C.-G. Lee; T. Katakai; Y. Agata; Y. Yokota; A. Shimizu Transcription-Coupled Events Associating with Immunoglobulin Switch Region Chromatin Transcription-Coupled Events Associating with Immunoglobulin Switch Region Chromatin Transcription-Coupled Events Associating with Immunoglobulin Switch Region Chromatin Science,302,5653,2137-2140 Science,302,5653,2137-2140 Science,302,5653,2137-2140 2003/12 英語 研究論文(学術雑誌) 公開
T. Kusunoki; M. Sugai; T. Katakai; Y. Omatsu; T. Iyoda; K. Inaba; T. Nakahata; A. Shimizu; Y. Yokota T. Kusunoki; M. Sugai; T. Katakai; Y. Omatsu; T. Iyoda; K. Inaba; T. Nakahata; A. Shimizu; Y. Yokota T. Kusunoki; M. Sugai; T. Katakai; Y. Omatsu; T. Iyoda; K. Inaba; T. Nakahata; A. Shimizu; Y. Yokota T<sub>H</sub>2 dominance and defective development of a CD8<sup>+</sup> dendritic cell subset in Id2-deficient mice T<sub>H</sub>2 dominance and defective development of a CD8<sup>+</sup> dendritic cell subset in Id2-deficient mice T<sub>H</sub>2 dominance and defective development of a CD8<sup>+</sup> dendritic cell subset in Id2-deficient mice Journal of Allergy and Clinical Immunology,111,1,136-142 Journal of Allergy and Clinical Immunology,111,1,136-142 Journal of Allergy and Clinical Immunology,111,1,136-142 2003/01 英語 研究論文(学術雑誌) 公開
M. Sugai; H. Gonda; T. Kusunoki; T. Katakai; Y. Yokota; A. Shimizu M. Sugai; H. Gonda; T. Kusunoki; T. Katakai; Y. Yokota; A. Shimizu M. Sugai; H. Gonda; T. Kusunoki; T. Katakai; Y. Yokota; A. Shimizu Essential role of Id2 in negative regulation of IgE class switching Essential role of Id2 in negative regulation of IgE class switching Essential role of Id2 in negative regulation of IgE class switching Nature Immunology,4,1,25-30 Nature Immunology,4,1,25-30 Nature Immunology,4,1,25-30 2003/01 英語 研究論文(学術雑誌) 公開
H. Gonda; M. Sugai; Y. Nambu; T. Katakai; Y. Agata; K.J. Mori; Y. Yokota; A. Shimizu H. Gonda; M. Sugai; Y. Nambu; T. Katakai; Y. Agata; K.J. Mori; Y. Yokota; A. Shimizu H. Gonda; M. Sugai; Y. Nambu; T. Katakai; Y. Agata; K.J. Mori; Y. Yokota; A. Shimizu The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression Journal of Experimental Medicine,198,9,1427-1437 Journal of Experimental Medicine,198,9,1427-1437 Journal of Experimental Medicine,198,9,1427-1437 2003 英語 研究論文(学術雑誌) 公開
T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; A. Shimizu Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis Th1-biased tertiary lymphoid tissue supported by CXC chemokine ligand 13-producing stromal network in chronic lesions of autoimmune gastritis Journal of Immunology,171,8,4359-4368 Journal of Immunology,171,8,4359-4368 Journal of Immunology,171,8,4359-4368 2003 英語 研究論文(学術雑誌) 公開
T. Katakai; K.J. Mori; T. Masuda; A. Shimizu T. Katakai; K.J. Mori; T. Masuda; A. Shimizu T. Katakai; K.J. Mori; T. Masuda; A. Shimizu Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or α<sub>4</sub>β<sub>7</sub>-integrin at the lesions of autoimmune gastritis Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or α<sub>4</sub>β<sub>7</sub>-integrin at the lesions of autoimmune gastritis Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or α<sub>4</sub>β<sub>7</sub>-integrin at the lesions of autoimmune gastritis International Immunology,14,2,167-175 International Immunology,14,2,167-175 International Immunology,14,2,167-175 2002 英語 研究論文(学術雑誌) 公開
T. Katakai; T. Hara; M. Sugai; H. Gonda; Y. Nambu; E. Matsuda; Y. Agata; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; Y. Nambu; E. Matsuda; Y. Agata; A. Shimizu T. Katakai; T. Hara; M. Sugai; H. Gonda; Y. Nambu; E. Matsuda; Y. Agata; A. Shimizu Chemokine-independent preference for T-helper-1 cells in transendothelial migration Chemokine-independent preference for T-helper-1 cells in transendothelial migration Chemokine-independent preference for T-helper-1 cells in transendothelial migration Journal of Biological Chemistry,277,52,50948-50958 Journal of Biological Chemistry,277,52,50948-50958 Journal of Biological Chemistry,277,52,50948-50958 2002 英語 研究論文(学術雑誌) 公開
H. Arakawa; K.-I. Kuma; M. Yasuda; S. Ekino; A. Shimizu; H. Yamagishi H. Arakawa; K.-I. Kuma; M. Yasuda; S. Ekino; A. Shimizu; H. Yamagishi H. Arakawa; K.-I. Kuma; M. Yasuda; S. Ekino; A. Shimizu; H. Yamagishi Effect of environmental antigens on the Ig diversification and the selection of productive V-J joints in the bursa Effect of environmental antigens on the Ig diversification and the selection of productive V-J joints in the bursa Effect of environmental antigens on the Ig diversification and the selection of productive V-J joints in the bursa Journal of Immunology,169,2,818-828 Journal of Immunology,169,2,818-828 Journal of Immunology,169,2,818-828 2002 英語 研究論文(学術雑誌) 公開
E. Matsuda; Y. Agata; M. Sugai; T. Katakai; H. Gonda; A. Shimizu E. Matsuda; Y. Agata; M. Sugai; T. Katakai; H. Gonda; A. Shimizu E. Matsuda; Y. Agata; M. Sugai; T. Katakai; H. Gonda; A. Shimizu Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms Targeting of Krüppel-associated box-containing zinc finger proteins to centromeric heterochromatin. Implication for the gene silencing mechanisms Journal of Biological Chemistry,276,17,14222-14229 Journal of Biological Chemistry,276,17,14222-14229 Journal of Biological Chemistry,276,17,14222-14229 2001/04 英語 研究論文(学術雑誌) 公開
Y. Agata; T. Katakai; S.-K. Ye; M. Sugai; H. Gonda; T. Honjo; K. Ikuta; A. Shimizu Y. Agata; T. Katakai; S.-K. Ye; M. Sugai; H. Gonda; T. Honjo; K. Ikuta; A. Shimizu Y. Agata; T. Katakai; S.-K. Ye; M. Sugai; H. Gonda; T. Honjo; K. Ikuta; A. Shimizu Histone acetylation determines the developmentally regulated accessibility for T cell receptor γ gene recombination Histone acetylation determines the developmentally regulated accessibility for T cell receptor γ gene recombination Histone acetylation determines the developmentally regulated accessibility for T cell receptor γ gene recombination Journal of Experimental Medicine,193,7,873-879 Journal of Experimental Medicine,193,7,873-879 Journal of Experimental Medicine,193,7,873-879 2001/04 英語 研究論文(学術雑誌) 公開
H. Gonda; M. Sugai; T. Katakai; N. Sugo; Y. Aratani; H. Koyama; K.J. Mori; A. Shimizu H. Gonda; M. Sugai; T. Katakai; N. Sugo; Y. Aratani; H. Koyama; K.J. Mori; A. Shimizu H. Gonda; M. Sugai; T. Katakai; N. Sugo; Y. Aratani; H. Koyama; K.J. Mori; A. Shimizu DNA polymerase β is not essential for the formation of palindromic (P) region of T cell receptor gene DNA polymerase β is not essential for the formation of palindromic (P) region of T cell receptor gene DNA polymerase β is not essential for the formation of palindromic (P) region of T cell receptor gene Immunology Letters,78,1,45-49 Immunology Letters,78,1,45-49 Immunology Letters,78,1,45-49 2001 英語 研究論文(学術雑誌) 公開
S.-K. Ye; Y. Agata; H.-C. Lee; H. Kurooka; T. Kitamura; A. Shimizu; T. Honjo; K. Ikuta S.-K. Ye; Y. Agata; H.-C. Lee; H. Kurooka; T. Kitamura; A. Shimizu; T. Honjo; K. Ikuta S.-K. Ye; Y. Agata; H.-C. Lee; H. Kurooka; T. Kitamura; A. Shimizu; T. Honjo; K. Ikuta The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation Immunity,15,5,813-823 Immunity,15,5,813-823 Immunity,15,5,813-823 2001 英語 研究論文(学術雑誌) 公開
H. Kitao; H. Arakawa; K.-I. Kuma; H. Yamagishi; N. Nakamura; S. Furusawa; H. Matsuda; M. Yasuda; S. Ekino; A. Shimizu H. Kitao; H. Arakawa; K.-I. Kuma; H. Yamagishi; N. Nakamura; S. Furusawa; H. Matsuda; M. Yasuda; S. Ekino; A. Shimizu H. Kitao; H. Arakawa; K.-I. Kuma; H. Yamagishi; N. Nakamura; S. Furusawa; H. Matsuda; M. Yasuda; S. Ekino; A. Shimizu Class switch recombination of the chicken IgH chain genes: Implications for the primordial switch region repeats Class switch recombination of the chicken IgH chain genes: Implications for the primordial switch region repeats Class switch recombination of the chicken IgH chain genes: Implications for the primordial switch region repeats International Immunology,12,7,959-968 International Immunology,12,7,959-968 International Immunology,12,7,959-968 2000 英語 研究論文(学術雑誌) 公開
Y. Yokota; S. Mori; S.-I. Nishikawa; A. Mansouri; P. Gruss; T. Kusunoki; T. Katakai; A. Shimizu Y. Yokota; S. Mori; S.-I. Nishikawa; A. Mansouri; P. Gruss; T. Kusunoki; T. Katakai; A. Shimizu Y. Yokota; S. Mori; S.-I. Nishikawa; A. Mansouri; P. Gruss; T. Kusunoki; T. Katakai; A. Shimizu The helix-loop-helix inhibitor Id2 and cell differentiation control The helix-loop-helix inhibitor Id2 and cell differentiation control The helix-loop-helix inhibitor Id2 and cell differentiation control Current Topics in Microbiology and Immunology,251,35-41 Current Topics in Microbiology and Immunology,251,35-41 Current Topics in Microbiology and Immunology,251,35-41 2000 英語 研究論文(学術雑誌) 公開
T. Akasaka; H. Akasaka; C. Ueda; N. Yonetani; Y. Maesako; A. Shimizu; H. Yamabe; S. Fukuhara; T. Uchiyama; H. Ohno T. Akasaka; H. Akasaka; C. Ueda; N. Yonetani; Y. Maesako; A. Shimizu; H. Yamabe; S. Fukuhara; T. Uchiyama; H. Ohno T. Akasaka; H. Akasaka; C. Ueda; N. Yonetani; Y. Maesako; A. Shimizu; H. Yamabe; S. Fukuhara; T. Uchiyama; H. Ohno Molecular and clinical features of non-Burkitt\\'s, diffuse large-cell lymphoma of B-cell type associated with the e-MYC/immunoglobulin heavy-chain fusion gene Molecular and clinical features of non-Burkitt\\'s, diffuse large-cell lymphoma of B-cell type associated with the e-MYC/immunoglobulin heavy-chain fusion gene Molecular and clinical features of non-Burkitt\\'s, diffuse large-cell lymphoma of B-cell type associated with the e-MYC/immunoglobulin heavy-chain fusion gene Journal of Clinical Oncology,18,3,510-518 Journal of Clinical Oncology,18,3,510-518 Journal of Clinical Oncology,18,3,510-518 2000 英語 研究論文(学術雑誌) 公開
H. Akasaka; T. Akasaka; M. Kurata; C. Ueda; A. Shimizu; T. Uchiyama; H. Ohno H. Akasaka; T. Akasaka; M. Kurata; C. Ueda; A. Shimizu; T. Uchiyama; H. Ohno H. Akasaka; T. Akasaka; M. Kurata; C. Ueda; A. Shimizu; T. Uchiyama; H. Ohno Molecular anatomy of BCL6 translocations revealed by long-distance polymerase chain reaction-based assays Molecular anatomy of BCL6 translocations revealed by long-distance polymerase chain reaction-based assays Molecular anatomy of BCL6 translocations revealed by long-distance polymerase chain reaction-based assays Cancer Research,60,9,2335-2341 Cancer Research,60,9,2335-2341 Cancer Research,60,9,2335-2341 2000 英語 研究論文(学術雑誌) 公開
Y. Agata; E. Matsuda; A. Shimizu Y. Agata; E. Matsuda; A. Shimizu Y. Agata; E. Matsuda; A. Shimizu Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1 β/KRIP-1) Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1 β/KRIP-1) Two novel Kruppel-associated box-containing zinc-finger proteins, KRAZ1 and KRAZ2, repress transcription through functional interaction with the corepressor KAP-1 (TIF1 β/KRIP-1) Journal of Biological Chemistry,274,23,16412-16422 Journal of Biological Chemistry,274,23,16412-16422 Journal of Biological Chemistry,274,23,16412-16422 1999/06 英語 研究論文(学術雑誌) 公開
M. Shimada; M. Saito; T. Katakai; A. Shimizu; T. Ichimura; S. Omata; T. Horigome M. Shimada; M. Saito; T. Katakai; A. Shimizu; T. Ichimura; S. Omata; T. Horigome M. Shimada; M. Saito; T. Katakai; A. Shimizu; T. Ichimura; S. Omata; T. Horigome Molecular cloning and splicing isoforms of mouse p144, a homologue of CA150 Molecular cloning and splicing isoforms of mouse p144, a homologue of CA150 Molecular cloning and splicing isoforms of mouse p144, a homologue of CA150 Journal of Biochemistry,126,6,1033-1042 Journal of Biochemistry,126,6,1033-1042 Journal of Biochemistry,126,6,1033-1042 1999 英語 研究論文(学術雑誌) 公開
M. Sugai; S. Kondo; A. Shimizu; T. Honjo M. Sugai; S. Kondo; A. Shimizu; T. Honjo M. Sugai; S. Kondo; A. Shimizu; T. Honjo Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase Nucleic Acids Research,26,4,911-918 Nucleic Acids Research,26,4,911-918 Nucleic Acids Research,26,4,911-918 1998/02 英語 研究論文(学術雑誌) 公開
T. Katakai; K.J. Mori; T. Masuda; A. Shimizu T. Katakai; K.J. Mori; T. Masuda; A. Shimizu T. Katakai; K.J. Mori; T. Masuda; A. Shimizu Differential localization of T(h)1 and T(h)2 cells in autoimmune gastritis Differential localization of T(h)1 and T(h)2 cells in autoimmune gastritis Differential localization of T(h)1 and T(h)2 cells in autoimmune gastritis International Immunology,10,9,1325-1334 International Immunology,10,9,1325-1334 International Immunology,10,9,1325-1334 1998 英語 研究論文(学術雑誌) 公開
Y. Agata; E. Matsuda; A. Shimizu Y. Agata; E. Matsuda; A. Shimizu Y. Agata; E. Matsuda; A. Shimizu Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc finger proteins by degenerate PCR Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc finger proteins by degenerate PCR Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc finger proteins by degenerate PCR Gene,213,1/2,55-64 Gene,213,1/2,55-64 Gene,213,1/2,55-64 1998 英語 研究論文(学術雑誌) 公開
T. Katakai; Y. Agata; A. Shimizu; C. Ohshima; A. Nishio; M. Inaba; S. Kasakura; K.J. Mori; T. Masuda T. Katakai; Y. Agata; A. Shimizu; C. Ohshima; A. Nishio; M. Inaba; S. Kasakura; K.J. Mori; T. Masuda T. Katakai; Y. Agata; A. Shimizu; C. Ohshima; A. Nishio; M. Inaba; S. Kasakura; K.J. Mori; T. Masuda Structure of the TCR expressed on a gastritogenic T cell clone, IL-6, and frequent appearance of similar clonotypes in mice bearing autoimmune gastritis Structure of the TCR expressed on a gastritogenic T cell clone, IL-6, and frequent appearance of similar clonotypes in mice bearing autoimmune gastritis Structure of the TCR expressed on a gastritogenic T cell clone, IL-6, and frequent appearance of similar clonotypes in mice bearing autoimmune gastritis International Immunology,9,12,1849-1855 International Immunology,9,12,1849-1855 International Immunology,9,12,1849-1855 1997/12 英語 研究論文(学術雑誌) 公開
H. Kitao; H. Arakawa; H. Yamagishi; A. Shimizu H. Kitao; H. Arakawa; H. Yamagishi; A. Shimizu H. Kitao; H. Arakawa; H. Yamagishi; A. Shimizu Chicken immunoglobulin μ-chain gene: Germline organization and tandem repeats characteristic of class switch recombination Chicken immunoglobulin μ-chain gene: Germline organization and tandem repeats characteristic of class switch recombination Chicken immunoglobulin μ-chain gene: Germline organization and tandem repeats characteristic of class switch recombination Immunology Letters,52,2-3,99-104 Immunology Letters,52,2-3,99-104 Immunology Letters,52,2-3,99-104 1996 英語 研究論文(学術雑誌) 公開
A. Shimizu A. Shimizu Analysis of regulatory mechanism for humoral immunity using transgenic mice of rearranged immunoglobulin genes Analysis of regulatory mechanism for humoral immunity using transgenic mice of rearranged immunoglobulin genes Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,40,14,2107-2117 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,40,14,2107-2117 ,40,14,2107-2117 1995 日本語 公開
T. Iwasato; Y. Kanari; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; Y. Kanari; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; Y. Kanari; A. Shimizu; T. Honjo; H. Yamagishi Transforming growth factor-β induced class switch recombination may be modified during the cell proliferation restored by IL-2 stimulation Transforming growth factor-β induced class switch recombination may be modified during the cell proliferation restored by IL-2 stimulation Transforming growth factor-β induced class switch recombination may be modified during the cell proliferation restored by IL-2 stimulation Immunology Letters,39,2,173-178 Immunology Letters,39,2,173-178 Immunology Letters,39,2,173-178 1994 英語 研究論文(学術雑誌) 公開
A. Shimizu; T. Honjo A. Shimizu; T. Honjo A. Shimizu; T. Honjo Synthesis and regulation of trans-mRNA encoding the immunoglobulin ∈ heavy chain Synthesis and regulation of trans-mRNA encoding the immunoglobulin ∈ heavy chain Synthesis and regulation of trans-mRNA encoding the immunoglobulin ∈ heavy chain FASEB Journal,7,1,149-154 FASEB Journal,7,1,149-154 FASEB Journal,7,1,149-154 1993/01 英語 研究論文(学術雑誌) 公開
T.-R. Mizuta; Y. Fukita; T. Miyoshi; A. Shimizu; T. Honjo T.-R. Mizuta; Y. Fukita; T. Miyoshi; A. Shimizu; T. Honjo T.-R. Mizuta; Y. Fukita; T. Miyoshi; A. Shimizu; T. Honjo Isolation of cDNA encoding a binding protein specific to 5′-phosphorylated single-stranded DNA with G-rich sequences Isolation of cDNA encoding a binding protein specific to 5′-phosphorylated single-stranded DNA with G-rich sequences Isolation of cDNA encoding a binding protein specific to 5′-phosphorylated single-stranded DNA with G-rich sequences Nucleic Acids Research,21,8,1761-1766 Nucleic Acids Research,21,8,1761-1766 Nucleic Acids Research,21,8,1761-1766 1993 英語 研究論文(学術雑誌) 公開
Y. Fukita; T.-R. Mizuta; M. Shirozu; K. Ozawa; A. Shimizu; T. Honjo Y. Fukita; T.-R. Mizuta; M. Shirozu; K. Ozawa; A. Shimizu; T. Honjo Y. Fukita; T.-R. Mizuta; M. Shirozu; K. Ozawa; A. Shimizu; T. Honjo The human Sμbp-2, a DNA-binding protein specific to the single-stranded guanine-rich sequence related to the immunoglobulin μ chain switch region The human Sμbp-2, a DNA-binding protein specific to the single-stranded guanine-rich sequence related to the immunoglobulin μ chain switch region The human Sμbp-2, a DNA-binding protein specific to the single-stranded guanine-rich sequence related to the immunoglobulin μ chain switch region Journal of Biological Chemistry,268,23,17463-17470 Journal of Biological Chemistry,268,23,17463-17470 Journal of Biological Chemistry,268,23,17463-17470 1993 英語 研究論文(学術雑誌) 公開
H. Arakawa; T. Iwasato; H. Hayashida; A. Shimizu; T. Honjo; H. Yamagishi H. Arakawa; T. Iwasato; H. Hayashida; A. Shimizu; T. Honjo; H. Yamagishi H. Arakawa; T. Iwasato; H. Hayashida; A. Shimizu; T. Honjo; H. Yamagishi The complete murine immunoglobulin class switch region of the α heavy chain gene-hierarchic repetitive structure and recombination breakpoints The complete murine immunoglobulin class switch region of the α heavy chain gene-hierarchic repetitive structure and recombination breakpoints The complete murine immunoglobulin class switch region of the α heavy chain gene-hierarchic repetitive structure and recombination breakpoints Journal of Biological Chemistry,268,7,4651-4655 Journal of Biological Chemistry,268,7,4651-4655 Journal of Biological Chemistry,268,7,4651-4655 1993 英語 研究論文(学術雑誌) 公開
A. Shimizu A. Shimizu Molecular mechanism for immunoglobulin class switching and multiple isotype expression Molecular mechanism for immunoglobulin class switching and multiple isotype expression Seikagaku. The Journal of Japanese Biochemical Society,65,10,1271-1288 Seikagaku. The Journal of Japanese Biochemical Society,65,10,1271-1288 ,65,10,1271-1288 1993 日本語 公開
M. Murakami; T. Tsubata; M. Okamoto; A. Shimizu; S. Kumagai; H. Imura; T. Honjo M. Murakami; T. Tsubata; M. Okamoto; A. Shimizu; S. Kumagai; H. Imura; T. Honjo M. Murakami; T. Tsubata; M. Okamoto; A. Shimizu; S. Kumagai; H. Imura; T. Honjo Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice Nature,357,6373,77-80 Nature,357,6373,77-80 Nature,357,6373,77-80 1992/05 英語 研究論文(学術雑誌) 公開
M. Okamoto; M. Murakami; A. Shimizu; S. Ozaki; T. Tsubata; S.-I. Kumagai; T. Honjo M. Okamoto; M. Murakami; A. Shimizu; S. Ozaki; T. Tsubata; S.-I. Kumagai; T. Honjo M. Okamoto; M. Murakami; A. Shimizu; S. Ozaki; T. Tsubata; S.-I. Kumagai; T. Honjo A transgenic model of autoimmune hemolytic anemia A transgenic model of autoimmune hemolytic anemia A transgenic model of autoimmune hemolytic anemia Journal of Experimental Medicine,175,1,71-79 Journal of Experimental Medicine,175,1,71-79 Journal of Experimental Medicine,175,1,71-79 1992 英語 研究論文(学術雑誌) 公開
Y. Takahashi; A. Shimizu; T. Sakai; Y.-I. Endo; N. Osawa; H. Shisa; T. Honjo Y. Takahashi; A. Shimizu; T. Sakai; Y.-I. Endo; N. Osawa; H. Shisa; T. Honjo Y. Takahashi; A. Shimizu; T. Sakai; Y.-I. Endo; N. Osawa; H. Shisa; T. Honjo Mapping of the nu gene using congenic nude strains and in situ hybridization Mapping of the nu gene using congenic nude strains and in situ hybridization Mapping of the nu gene using congenic nude strains and in situ hybridization Journal of Experimental Medicine,175,3,873-876 Journal of Experimental Medicine,175,3,873-876 Journal of Experimental Medicine,175,3,873-876 1992 英語 研究論文(学術雑誌) 公開
T. Iwasato; H. Arakawa; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; H. Arakawa; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; H. Arakawa; A. Shimizu; T. Honjo; H. Yamagishi Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor β and lipopolysaccharide Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor β and lipopolysaccharide Biased distribution of recombination sites within S regions upon immunoglobulin class switch recombination induced by transforming growth factor β and lipopolysaccharide Journal of Experimental Medicine,175,6,1539-1546 Journal of Experimental Medicine,175,6,1539-1546 Journal of Experimental Medicine,175,6,1539-1546 1992 英語 研究論文(学術雑誌) 公開
Manfred Baetscher, Manfred Baetscher, Emmett Schmidt, Akira Shimizu, Akira Shimizu, Philip Leder, Philip Leder, Philip Leder, Mark C. Fishman, Mark C. Fishman, Mark C. Fishman Manfred Baetscher, Manfred Baetscher, Emmett Schmidt, Akira Shimizu, Akira Shimizu, Philip Leder, Philip Leder, Philip Leder, Mark C. Fishman, Mark C. Fishman, Mark C. Fishman Manfred Baetscher, Manfred Baetscher, Emmett Schmidt, Akira Shimizu, Akira Shimizu, Philip Leder, Philip Leder, Philip Leder, Mark C. Fishman, Mark C. Fishman, Mark C. Fishman SV40 T antigen transforms calcitonin cells of the thyroid but not CGRP-containing neurons in transgenic mice SV40 T antigen transforms calcitonin cells of the thyroid but not CGRP-containing neurons in transgenic mice SV40 T antigen transforms calcitonin cells of the thyroid but not CGRP-containing neurons in transgenic mice Oncogene,6,1133-1138 Oncogene,6,1133-1138 Oncogene,6,1133-1138 1991/07/01 公開
A. Shimizu; M.C. Nussenzweig; H. Han; M. Sanchez; T. Honjo A. Shimizu; M.C. Nussenzweig; H. Han; M. Sanchez; T. Honjo A. Shimizu; M.C. Nussenzweig; H. Han; M. Sanchez; T. Honjo Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene Journal of Experimental Medicine,173,6,1385-1393 Journal of Experimental Medicine,173,6,1385-1393 Journal of Experimental Medicine,173,6,1385-1393 1991/06 英語 研究論文(学術雑誌) 公開
K. Kuze; A. Shimizu; T. Honjo K. Kuze; A. Shimizu; T. Honjo K. Kuze; A. Shimizu; T. Honjo Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of human immunoglobulin Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of human immunoglobulin Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of human immunoglobulin International Immunology,3,7,647-655 International Immunology,3,7,647-655 International Immunology,3,7,647-655 1991 英語 研究論文(学術雑誌) 公開
K. Kinoshita; A. Shimizu; T. Honjo K. Kinoshita; A. Shimizu; T. Honjo K. Kinoshita; A. Shimizu; T. Honjo The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene Immunology Letters,27,2,151-155 Immunology Letters,27,2,151-155 Immunology Letters,27,2,151-155 1991 英語 研究論文(学術雑誌) 公開
H. Han; M. Okamoto; T. Honjo; A. Shimizu H. Han; M. Okamoto; T. Honjo; A. Shimizu H. Han; M. Okamoto; T. Honjo; A. Shimizu Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic μ chain and constant regions of endogenous isotypes Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic μ chain and constant regions of endogenous isotypes Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic μ chain and constant regions of endogenous isotypes International Immunology,3,12,1197-1206 International Immunology,3,12,1197-1206 International Immunology,3,12,1197-1206 1991 英語 研究論文(学術雑誌) 公開
T.-R. Mizuta; N. Suzuki; A. Shimizu; T. Honjo T.-R. Mizuta; N. Suzuki; A. Shimizu; T. Honjo T.-R. Mizuta; N. Suzuki; A. Shimizu; T. Honjo Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells Journal of Biological Chemistry,266,19,12514-12521 Journal of Biological Chemistry,266,19,12514-12521 Journal of Biological Chemistry,266,19,12514-12521 1991 英語 研究論文(学術雑誌) 公開
T. Iwasato; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; A. Shimizu; T. Honjo; H. Yamagishi T. Iwasato; A. Shimizu; T. Honjo; H. Yamagishi Circular DNA is excised by immunoglobulin class switch recombination Circular DNA is excised by immunoglobulin class switch recombination Circular DNA is excised by immunoglobulin class switch recombination Cell,62,1,143-149 Cell,62,1,143-149 Cell,62,1,143-149 1990/07 英語 研究論文(学術雑誌) 公開
Tepler I, Morton CC, Shimizu A, Holcombe RF, Eddy R, Shows TB, Leder P Tepler I, Morton CC, Shimizu A, Holcombe RF, Eddy R, Shows TB, Leder P Tepler I, Morton CC, Shimizu A, Holcombe RF, Eddy R, Shows TB, Leder P The gene for the human mast cell high-affinity IgE receptor alpha chain: chromosomal localization to Iq21-q23 and RFLP analysis. The gene for the human mast cell high-affinity IgE receptor alpha chain: chromosomal localization to Iq21-q23 and RFLP analysis. The gene for the human mast cell high-affinity IgE receptor alpha chain: chromosomal localization to Iq21-q23 and RFLP analysis. American journal of human genetics,45,5,761-765 American journal of human genetics,45,5,761-765 American journal of human genetics,45,5,761-765 1989/11 公開
Tepler I, Shimizu A, Leder P Tepler I, Shimizu A, Leder P Tepler I, Shimizu A, Leder P The gene for the rat mast cell high affinity IgE receptor alpha chain. Structure and alternative mRNA splicing patterns. The gene for the rat mast cell high affinity IgE receptor alpha chain. Structure and alternative mRNA splicing patterns. The gene for the rat mast cell high affinity IgE receptor alpha chain. Structure and alternative mRNA splicing patterns. The Journal of biological chemistry,264,10,5912-5915 The Journal of biological chemistry,264,10,5912-5915 The Journal of biological chemistry,264,10,5912-5915 1989/04 公開
Hiroshi Kajitani, Hideo Enokihara, Satoshi Tsunogake, Naoto Takano, Kenji Saito, Shimpei Furusawa, Hideo Shishido, Takafumi Noma, Akira Shimizu, Tasuku Honjo Hiroshi Kajitani, Hideo Enokihara, Satoshi Tsunogake, Naoto Takano, Kenji Saito, Shimpei Furusawa, Hideo Shishido, Takafumi Noma, Akira Shimizu, Tasuku Honjo Hiroshi Kajitani, Hideo Enokihara, Satoshi Tsunogake, Naoto Takano, Kenji Saito, Shimpei Furusawa, Hideo Shishido, Takafumi Noma, Akira Shimizu, Tasuku Honjo Effect of human recombinant interleukin 4 on in vitro granulopoiesis of human bone marrow cells Effect of human recombinant interleukin 4 on in vitro granulopoiesis of human bone marrow cells Effect of human recombinant interleukin 4 on in vitro granulopoiesis of human bone marrow cells Growth Factors,1,283-286 Growth Factors,1,283-286 Growth Factors,1,283-286 1989/01/01 公開
A. Shimizu, M. C. Nussenzweig, T. R. Mizuta, P. Leder, T. Honjo A. Shimizu, M. C. Nussenzweig, T. R. Mizuta, P. Leder, T. Honjo A. Shimizu; M.C. Nussenzweig; T.-R. Mizuta; P. Leder; T. Honjo Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse Proceedings of the National Academy of Sciences of the United States of America,86,20,8020-8023 Proceedings of the National Academy of Sciences of the United States of America,86,20,8020-8023 Proceedings of the National Academy of Sciences of the United States of America,86,20,8020-8023 1989/01 英語 研究論文(学術雑誌) 公開
T. Noma; H. Nakakubo; M. Sugita; S. Kumagi; M. Maeda; A. Shimizu; T. Honjo T. Noma; H. Nakakubo; M. Sugita; S. Kumagi; M. Maeda; A. Shimizu; T. Honjo T. Noma; H. Nakakubo; M. Sugita; S. Kumagi; M. Maeda; A. Shimizu; T. Honjo Expression of different combinations of interleukins by human T cell leukemic cell lines that are clonally related Expression of different combinations of interleukins by human T cell leukemic cell lines that are clonally related Expression of different combinations of interleukins by human T cell leukemic cell lines that are clonally related Journal of Experimental Medicine,169,5,1853-1858 Journal of Experimental Medicine,169,5,1853-1858 Journal of Experimental Medicine,169,5,1853-1858 1989 英語 研究論文(学術雑誌) 公開
P. Sideras; T.-R. Mizuta; H. Kanamori; N. Suzuki; M. Okamoto; K. Kuze; H. Ohno; S. Doi; S. Fukuhara; M.S. Hassan; L. Hammarstrom; E. Smith; A. Shimizu; T. Honjo P. Sideras; T.-R. Mizuta; H. Kanamori; N. Suzuki; M. Okamoto; K. Kuze; H. Ohno; S. Doi; S. Fukuhara; M.S. Hassan; L. Hammarstrom; E. Smith; A. Shimizu; T. Honjo P. Sideras; T.-R. Mizuta; H. Kanamori; N. Suzuki; M. Okamoto; K. Kuze; H. Ohno; S. Doi; S. Fukuhara; M.S. Hassan; L. Hammarstrom; E. Smith; A. Shimizu; T. Honjo Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells International Immunology,1,6,631-642 International Immunology,1,6,631-642 International Immunology,1,6,631-642 1989 英語 研究論文(学術雑誌) 公開
K. Kuze; A. Shimizu; T. Honjo K. Kuze; A. Shimizu; T. Honjo K. Kuze; A. Shimizu; T. Honjo A new vector and RNase H method for the subtractive hybridization A new vector and RNase H method for the subtractive hybridization A new vector and RNase H method for the subtractive hybridization Nucleic Acids Research,17,2,807 Nucleic Acids Research,17,2,807 Nucleic Acids Research,17,2,807 1989 英語 研究論文(学術雑誌) 公開
A. Shimizu; T. Kinashi; M.C. Nussenzweig; T.-R. Mizuta; P. Leder; T. Honjo A. Shimizu; T. Kinashi; M.C. Nussenzweig; T.-R. Mizuta; P. Leder; T. Honjo A. Shimizu; T. Kinashi; M.C. Nussenzweig; T.-R. Mizuta; P. Leder; T. Honjo Molecular mechanism for immunoglobulin double-isotype expression Molecular mechanism for immunoglobulin double-isotype expression Molecular mechanism for immunoglobulin double-isotype expression Cold Spring Harbor Symposia on Quantitative Biology,54,1,175-181 Cold Spring Harbor Symposia on Quantitative Biology,54,1,175-181 Cold Spring Harbor Symposia on Quantitative Biology,54,1,175-181 1989 英語 研究論文(学術雑誌) 公開
A. Shimizu, I. Tepler, P. N. Benfey, E. H. Berenstein, R. P. Siraganian, P. Leder A. Shimizu, I. Tepler, P. N. Benfey, E. H. Berenstein, R. P. Siraganian, P. Leder A. Shimizu, I. Tepler, P. N. Benfey, E. H. Berenstein, R. P. Siraganian, P. Leder Human and rat mast cell high-affinity immunoglobulin E receptors: Characterization of putative α-chain gene products Human and rat mast cell high-affinity immunoglobulin E receptors: Characterization of putative α-chain gene products Human and rat mast cell high-affinity immunoglobulin E receptors: Characterization of putative α-chain gene products Proceedings of the National Academy of Sciences of the United States of America,85,6,1907-1911 Proceedings of the National Academy of Sciences of the United States of America,85,6,1907-1911 Proceedings of the National Academy of Sciences of the United States of America,85,6,1907-1911 1988/12 英語 研究論文(学術雑誌) 公開
N. Kondo; S. Kondo; A. Shimizu; T. Honjo; J. Hamuro N. Kondo; S. Kondo; A. Shimizu; T. Honjo; J. Hamuro N. Kondo; S. Kondo; A. Shimizu; T. Honjo; J. Hamuro A soluble \\'anchorminus\\' interleukin 2 receptor suppresses in vitro interleukin 2-mediated immune responses A soluble \\'anchorminus\\' interleukin 2 receptor suppresses in vitro interleukin 2-mediated immune responses A soluble \\'anchorminus\\' interleukin 2 receptor suppresses in vitro interleukin 2-mediated immune responses Immunology Letters,19,4,299-307 Immunology Letters,19,4,299-307 Immunology Letters,19,4,299-307 1988 英語 研究論文(学術雑誌) 公開
Y. Saito; H. Sabe; N. Suzuki; S. Kondo; T. Ogura; A. Shimizu; T. Honjo Y. Saito; H. Sabe; N. Suzuki; S. Kondo; T. Ogura; A. Shimizu; T. Honjo Y. Saito; H. Sabe; N. Suzuki; S. Kondo; T. Ogura; A. Shimizu; T. Honjo A larger number of L chains (Tac) enhance the association rate of interleukin 2 to the high affinity site of the interleukin 2 receptor A larger number of L chains (Tac) enhance the association rate of interleukin 2 to the high affinity site of the interleukin 2 receptor A larger number of L chains (Tac) enhance the association rate of interleukin 2 to the high affinity site of the interleukin 2 receptor Journal of Experimental Medicine,168,5,1563-1572 Journal of Experimental Medicine,168,5,1563-1572 Journal of Experimental Medicine,168,5,1563-1572 1988 英語 研究論文(学術雑誌) 公開
N. Harada; M. Matsumoto; N. Koyama; A. Shimizu; T. Honjo; A. Tominaga; K. Takatsu N. Harada; M. Matsumoto; N. Koyama; A. Shimizu; T. Honjo; A. Tominaga; K. Takatsu N. Harada; M. Matsumoto; N. Koyama; A. Shimizu; T. Honjo; A. Tominaga; K. Takatsu T cell replacing factor/interleukin 5 induces not only B-cell growth and differentiation, but also increased expression of interleukin 2 receptor on activated B-cells T cell replacing factor/interleukin 5 induces not only B-cell growth and differentiation, but also increased expression of interleukin 2 receptor on activated B-cells T cell replacing factor/interleukin 5 induces not only B-cell growth and differentiation, but also increased expression of interleukin 2 receptor on activated B-cells Immunology Letters,15,3,205-215 Immunology Letters,15,3,205-215 Immunology Letters,15,3,205-215 1987 英語 研究論文(学術雑誌) 公開
M. Maeda; N. Arima; Y. Daitoku; M. Kashihara; H. Okamoto; T. Uchiyama; K. Shirono; M. Matsuoka; T. Hattori; K. Takatsuki; K. Ikuta; A. Shimizu; T. Honjo; J. Yodoi M. Maeda; N. Arima; Y. Daitoku; M. Kashihara; H. Okamoto; T. Uchiyama; K. Shirono; M. Matsuoka; T. Hattori; K. Takatsuki; K. Ikuta; A. Shimizu; T. Honjo; J. Yodoi M. Maeda; N. Arima; Y. Daitoku; M. Kashihara; H. Okamoto; T. Uchiyama; K. Shirono; M. Matsuoka; T. Hattori; K. Takatsuki; K. Ikuta; A. Shimizu; T. Honjo; J. Yodoi Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia Blood,70,5,1407-1411 Blood,70,5,1407-1411 Blood,70,5,1407-1411 1987 英語 研究論文(学術雑誌) 公開
S. Kondo; M. Kinoshita; A. Shimizu S. Kondo; M. Kinoshita; A. Shimizu S. Kondo; M. Kinoshita; A. Shimizu Expression and function characterization of artificial mutants of interleukin-2 receptor Expression and function characterization of artificial mutants of interleukin-2 receptor Expression and function characterization of artificial mutants of interleukin-2 receptor Nature,327,6117,64-67 Nature,327,6117,64-67 Nature,327,6117,64-67 1987 英語 研究論文(学術雑誌) 公開
S. Kondo; A. Shimizu; M. Maeda; Y. Tagaya; J. Yodoi; T. Honjo S. Kondo; A. Shimizu; M. Maeda; Y. Tagaya; J. Yodoi; T. Honjo S. Kondo; A. Shimizu; M. Maeda; Y. Tagaya; J. Yodoi; T. Honjo Expression of functional human interleukin-2 receptor in mice T cells by cDNA transfection Expression of functional human interleukin-2 receptor in mice T cells by cDNA transfection Expression of functional human interleukin-2 receptor in mice T cells by cDNA transfection Nature,320,6057,75-77 Nature,320,6057,75-77 Nature,320,6057,75-77 1986/03 英語 研究論文(学術雑誌) 公開
A. Shimizu; S. Kondo; H. Sabe; N. Ishida; T. Honjo A. Shimizu; S. Kondo; H. Sabe; N. Ishida; T. Honjo A. Shimizu; S. Kondo; H. Sabe; N. Ishida; T. Honjo Structure and function of the interleukin 2 receptor: affinity conversion model. Structure and function of the interleukin 2 receptor: affinity conversion model. Structure and function of the interleukin 2 receptor: affinity conversion model. Immunological reviews,92,103-120 Immunological reviews,92,103-120 Immunological reviews,92,103-120 1986 英語 研究論文(学術雑誌) 公開
K. Ikuta; T. Ogura; A. Shimizu; T. Honjo K. Ikuta; T. Ogura; A. Shimizu; T. Honjo K. Ikuta; T. Ogura; A. Shimizu; T. Honjo A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the β-chain gene of the human T-cell receptor A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the β-chain gene of the human T-cell receptor A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the β-chain gene of the human T-cell receptor Nucleic Acids Research,14,12,4899-4909 Nucleic Acids Research,14,12,4899-4909 Nucleic Acids Research,14,12,4899-4909 1986 英語 研究論文(学術雑誌) 公開
A. Shimizu; N. Kondo; S. Kondo; J. Hamuro; T. Honjo A. Shimizu; N. Kondo; S. Kondo; J. Hamuro; T. Honjo A. Shimizu; N. Kondo; S. Kondo; J. Hamuro; T. Honjo Production and characterization of the extracytoplasmic portion of the human interleukin-2 receptor. Production and characterization of the extracytoplasmic portion of the human interleukin-2 receptor. Production and characterization of the extracytoplasmic portion of the human interleukin-2 receptor. Molecular biology & medicine,3,6,509-520 Molecular biology & medicine,3,6,509-520 Molecular biology & medicine,3,6,509-520 1986 英語 研究論文(学術雑誌) 公開
S. Kondo; A. Shimizu; Y. Saito; M. Kinoshita; T. Honjo S. Kondo; A. Shimizu; Y. Saito; M. Kinoshita; T. Honjo S. Kondo; A. Shimizu; Y. Saito; M. Kinoshita; T. Honjo Molecular basis for two different affinity states of the interleukin 2 receptor: Affinity conversion model Molecular basis for two different affinity states of the interleukin 2 receptor: Affinity conversion model Molecular basis for two different affinity states of the interleukin 2 receptor: Affinity conversion model Proceedings of the National Academy of Sciences of the United States of America,83,23,9026-9029 Proceedings of the National Academy of Sciences of the United States of America,83,23,9026-9029 Proceedings of the National Academy of Sciences of the United States of America,83,23,9026-9029 1986 英語 研究論文(学術雑誌) 公開
M. Maeda; A. Shimizu; K. Ikuta; H. Okamoto; M. Kashihara; T. Uchiyama; T. Honjo; J. Yodoi M. Maeda; A. Shimizu; K. Ikuta; H. Okamoto; M. Kashihara; T. Uchiyama; T. Honjo; J. Yodoi M. Maeda; A. Shimizu; K. Ikuta; H. Okamoto; M. Kashihara; T. Uchiyama; T. Honjo; J. Yodoi Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement Journal of Experimental Medicine,162,6,2169-2174 Journal of Experimental Medicine,162,6,2169-2174 Journal of Experimental Medicine,162,6,2169-2174 1985 英語 研究論文(学術雑誌) 公開
N. Ishida; H. Kanamori; T. Noma; T. Nikaido; H. Sabe; N. Suzuki; A. Shimizu; T. Honjo N. Ishida; H. Kanamori; T. Noma; T. Nikaido; H. Sabe; N. Suzuki; A. Shimizu; T. Honjo N. Ishida; H. Kanamori; T. Noma; T. Nikaido; H. Sabe; N. Suzuki; A. Shimizu; T. Honjo Molecular cloning and structure of the human interleukin 2 receptor gene Molecular cloning and structure of the human interleukin 2 receptor gene Molecular cloning and structure of the human interleukin 2 receptor gene Nucleic Acids Research,13,21,7579-7589 Nucleic Acids Research,13,21,7579-7589 Nucleic Acids Research,13,21,7579-7589 1985 英語 研究論文(学術雑誌) 公開
K. Ikuta; T. Ogura; A. Shimizu; T. Honjo K. Ikuta; T. Ogura; A. Shimizu; T. Honjo K. Ikuta; T. Ogura; A. Shimizu; T. Honjo Low frequency of somatic mutation in β-chain variable region genes of human T-cell receptors Low frequency of somatic mutation in β-chain variable region genes of human T-cell receptors Low frequency of somatic mutation in β-chain variable region genes of human T-cell receptors Proceedings of the National Academy of Sciences of the United States of America,82,22,7701-7705 Proceedings of the National Academy of Sciences of the United States of America,82,22,7701-7705 Proceedings of the National Academy of Sciences of the United States of America,82,22,7701-7705 1985 英語 研究論文(学術雑誌) 公開
A. Shimizu, T. Honjo A. Shimizu, T. Honjo A. Shimizu, T. Honjo Immunoglobulin class switching Immunoglobulin class switching Immunoglobulin class switching Cell,36,4,801-803 Cell,36,4,801-803 Cell,36,4,801-803 1984/01/01 公開
T. Nikaido; A. Shimizu; N. Ishida; H. Sabe; K. Teshigawara; M. Maeda; T. Uchiyama; J. Yodoi; T. Honjo T. Nikaido; A. Shimizu; N. Ishida; H. Sabe; K. Teshigawara; M. Maeda; T. Uchiyama; J. Yodoi; T. Honjo T. Nikaido; A. Shimizu; N. Ishida; H. Sabe; K. Teshigawara; M. Maeda; T. Uchiyama; J. Yodoi; T. Honjo Molecular cloning of cDNA encoding human interleukin-2 receptor Molecular cloning of cDNA encoding human interleukin-2 receptor Molecular cloning of cDNA encoding human interleukin-2 receptor Nature,311,5987,631-635 Nature,311,5987,631-635 Nature,311,5987,631-635 1984 英語 研究論文(学術雑誌) 公開
H. Sabe; S. Kondo; A. Shimizu; Y. Tagaya; J. Yodoi; N. Kobayashi; M. Hatanaka; N. Matsunami; M. Maeda; T. Noma H. Sabe; S. Kondo; A. Shimizu; Y. Tagaya; J. Yodoi; N. Kobayashi; M. Hatanaka; N. Matsunami; M. Maeda; T. Noma H. Sabe; S. Kondo; A. Shimizu; Y. Tagaya; J. Yodoi; N. Kobayashi; M. Hatanaka; N. Matsunami; M. Maeda; T. Noma Properties of human interleukin-2 receptors expressed on non-lymphoid cells by cDNA transfection Properties of human interleukin-2 receptors expressed on non-lymphoid cells by cDNA transfection Properties of human interleukin-2 receptors expressed on non-lymphoid cells by cDNA transfection Molecular Biology and Medicine,2,6,379-396 Molecular Biology and Medicine,2,6,379-396 Molecular Biology and Medicine,2,6,379-396 1984 英語 研究論文(学術雑誌) 公開
A. Shimizu; N. Takahashi; Y. Yaoita; T. Honjo A. Shimizu; N. Takahashi; Y. Yaoita; T. Honjo A. Shimizu; N. Takahashi; Y. Yaoita; T. Honjo Organization of the constant-region gene family of the mouse immunoglobulin heavy chain Organization of the constant-region gene family of the mouse immunoglobulin heavy chain Organization of the constant-region gene family of the mouse immunoglobulin heavy chain Cell,28,3,499-506 Cell,28,3,499-506 Cell,28,3,499-506 1982 英語 研究論文(学術雑誌) 公開
A. Shimizu; Y. Hamaguchi; Y. Yaoita; K. Moriwaki; K. Kondo; T. Honjo A. Shimizu; Y. Hamaguchi; Y. Yaoita; K. Moriwaki; K. Kondo; T. Honjo A. Shimizu; Y. Hamaguchi; Y. Yaoita; K. Moriwaki; K. Kondo; T. Honjo Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin γ2a genes Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin γ2a genes Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin γ2a genes Nature,298,5869,82-84 Nature,298,5869,82-84 Nature,298,5869,82-84 1982 英語 研究論文(学術雑誌) 公開
M. Obata, T. Kataoka, S. Nakai, H. Yamagishi, N. Takahashi, Y. Yamawaki-Kataoka, T. Nikaido, A. Shimizu, T. Honjo M. Obata, T. Kataoka, S. Nakai, H. Yamagishi, N. Takahashi, Y. Yamawaki-Kataoka, T. Nikaido, A. Shimizu, T. Honjo M. Obata; T. Kataoka; S. Nakai; H. Yamagishi; N. Takahashi; Y. Yamawaki-Kataoka; T. Nikaido; A. Shimizu; T. Honjo Structure of a rearranged γ1 chain gene and its implication to immunoglobulin class-switch mechanism Structure of a rearranged γ1 chain gene and its implication to immunoglobulin class-switch mechanism Structure of a rearranged γ1 chain gene and its implication to immunoglobulin class-switch mechanism Proceedings of the National Academy of Sciences of the United States of America,78,4 II,2437-2441 Proceedings of the National Academy of Sciences of the United States of America,78,4 II,2437-2441 Proceedings of the National Academy of Sciences of the United States of America,78,4 II,2437-2441 1981/11 英語 研究論文(学術雑誌) 公開
A. Shimizu; N. Takahashi; Y. Yamawaki-Kataoka; Y. Nishida; T. Kataoka; T. Honjo A. Shimizu; N. Takahashi; Y. Yamawaki-Kataoka; Y. Nishida; T. Kataoka; T. Honjo A. Shimizu; N. Takahashi; Y. Yamawaki-Kataoka; Y. Nishida; T. Kataoka; T. Honjo Ordering of mouse immunoglobulin heavy chain genes by molecular cloning Ordering of mouse immunoglobulin heavy chain genes by molecular cloning Ordering of mouse immunoglobulin heavy chain genes by molecular cloning Nature,289,5794,149-153 Nature,289,5794,149-153 Nature,289,5794,149-153 1981 英語 研究論文(学術雑誌) 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
櫛引俊宏,中島奈津紀,菅井学,清水章,田畑泰彦 櫛引俊宏,中島奈津紀,菅井学,清水章,田畑泰彦 カチオン化ゼラチンを用いたsiRNA の腎間質へのデリバリー カチオン化ゼラチンを用いたsiRNA の腎間質へのデリバリー 第54 回高分子学会年次大会(2005.5.25-27 横浜) 第54 回高分子学会年次大会(2005.5.25-27 横浜) 2005 日本語 公開
中島(長田)奈津紀,權田裕之,田畑泰彦,横田義史,清水章,菅井学 中島(長田)奈津紀,權田裕之,田畑泰彦,横田義史,清水章,菅井学 分化抑制因子Id2 によるB 細胞最終分化抑制機構の解析 分化抑制因子Id2 によるB 細胞最終分化抑制機構の解析 第28 回日本分子生物学会年会(2005.12.7-10 福岡) 第28 回日本分子生物学会年会(2005.12.7-10 福岡) 2005 日本語 公開
櫛引俊宏,中島奈津紀,菅井学,清水章,田畑泰彦 櫛引俊宏,中島奈津紀,菅井学,清水章,田畑泰彦 カチオン化ゼラチンを利用したsiRNA 発現ベクターに よる腎線維化進展抑制 カチオン化ゼラチンを利用したsiRNA 発現ベクターに よる腎線維化進展抑制 第20 回日本DDS 学会学術集会(2004.7.15-16. 京都) 第20 回日本DDS 学会学術集会(2004.7.15-16. 京都) 2004 日本語 公開
Tomoya Katakai, Takashi Nomura, Hiroyuki Gonda, Manabu Sugai, Shimon Sakaguchi, Akira Shimizu. Tomoya Katakai, Takashi Nomura, Hiroyuki Gonda, Manabu Sugai, Shimon Sakaguchi, Akira Shimizu. Spontaneous lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-reactive TCR transgenic mouse. Spontaneous lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-reactive TCR transgenic mouse. 第36 回日本免疫学会総会(2006.12.11-13. 大阪) 第36 回日本免疫学会総会(2006.12.11-13. 大阪) 2006/12/11 英語 公開
Kushibiki, T., Nagata-Nakajima, N., Sugai, M., Shimizu, A., Tabata, Y. Kushibiki, T., Nagata-Nakajima, N., Sugai, M., Shimizu, A., Tabata, Y. Delivery of small interference RNA of transforming \ngrowth factor beta 1 receptor by cationized gelatin. Delivery of small interference RNA of transforming \ngrowth factor beta 1 receptor by cationized gelatin. 4th Asian International Symposium on Biomaterials (AISB4)and 2nd International Symposium on Fusion of Nano and Bio Technologies(FNB)(2004.11.16-18. Tsukuba) 4th Asian International Symposium on Biomaterials (AISB4)and 2nd International Symposium on Fusion of Nano and Bio Technologies(FNB)(2004.11.16-18. Tsukuba) 2004/11/16 英語 公開
タイトル言語:
学術賞等
賞の名称(日本語) 賞の名称(英語) 授与組織名(日本語) 授与組織名(英語) 年月
日本生化学会奨励賞 Young Investigator Award 日本生化学会 The Japanese Biochemical Society 1991
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(B) 微小環境構築と転写ネットワーク解析による免疫反応制御の分子機構解明 2009〜2012
挑戦的萌芽研究 代表 クラススイッチ組換え制御によるアレルギー制御・治療法の探索 2012〜2013
基盤研究(B) 代表 抗原特異的免疫反応制御機構の分子基盤 2013〜2016
基盤研究(B) 代表 抗原特異的免疫反応制御機構の分子基盤 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(B) 代表 抗原特異的免疫反応制御機構の分子基盤 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(B) 代表 抗原特異的免疫反応制御機構の分子基盤 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究B 代表 CD4T細胞から分化誘導される新規制御性T細胞の機能解析 2017/04/01〜2020/03/31
基盤研究(B) 代表 CD4T細胞から分化誘導される新規制御性T細胞の機能解析 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(B) 代表 抗原特異的免疫反応制御機構の分子基盤 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究B 代表 CD4T細胞から分化誘導される新規制御性T細胞の機能解析 (平成30年度分) 2018/04/01〜2019/03/31
外部資金:競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
文部科学省 橋渡し研究加速ネットワークプログラム 高橋良輔 創薬・新規医療開発のアカデミア拠点強化 Reinforcement of academic base for development of innovative new drug and medical treatment 2012〜2016
文部科学省 橋渡し研究加戦略的推進プログラム 松田秀一 アカデミア発先端医療技術の早期実用化に向けた実践と連携 Clinical development to make medical technology fit for practical use 2017/04/01〜2018/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 前期集中 生命科学研究科 2013/04〜2014/03
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 前期集中 生命科学研究科 2014/04〜2015/03
特別実験及び演習第1 Experimental Course and Seminar l 通年 生命科学研究科 2014/04〜2015/03
特別実験及び演習第2 Experimental Course and Seminar 2 通年 生命科学研究科 2014/04〜2015/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 通年 生命科学研究科 2014/04〜2015/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2015/04〜2016/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2015/04〜2016/03
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 後期集中 生命科学研究科 2015/04〜2016/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2015/04〜2016/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2015/04〜2016/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2016/04〜2017/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2016/04〜2017/03
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 前期集中 生命科学研究科 2016/04〜2017/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2016/04〜2017/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2016/04〜2017/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2017/04〜2018/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2017/04〜2018/03
生物・生命科学入門 Introduction to Biology and Life Science 前期 全学共通科目 2017/04〜2018/03
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 後期集中 生命科学研究科 2017/04〜2018/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2017/04〜2018/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2017/04〜2018/03
特別実験及び演習A Experimental Course and Seminar A 前期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習A Experimental Course and Seminar A 後期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習B Experimental Course and Seminar B 前期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習B Experimental Course and Seminar B 後期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習C Experimental Course and Seminar C 前期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習C Experimental Course and Seminar C 後期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習D Experimental Course and Seminar D 前期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習D Experimental Course and Seminar D 後期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2018/04〜2019/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2018/04〜2019/03
疾患・免疫生命科学特論 Advanced Course in Immunology and Human Disorders 前期集中 生命科学研究科 2018/04〜2019/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2018/04〜2019/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2018/04〜2019/03

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全学運営(役職等)
役職名 期間
産官学連携本部運営協議会 委員 2008/04/01〜2011/03/31
放射性同位元素等管理委員会 委員 2008/04/01〜2011/03/31
組換えDNA実験安全委員会 委員長 2008/04/01〜2011/03/31
総長室特命補佐 2008/10/01〜2010/09/30
産官学連携本部運営協議会 2011/04/01〜2013/03/31
京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員 2008/04/01〜2013/09/10
産官学連携本部運営協議会 2013/04/01〜2015/03/31
京都大学組み換えDNA実験安全委員会 委員長 2010/10/01〜2014/09/30
産官学連携本部運営協議会協議員 委員 2013/04/01〜2015/03/31
ヒトゲノム・遺伝子解析研究管理委員会 委員 2013/09/11〜2015/12/31
組換えDNA実験安全委員会 1号委員 2014/10/01〜2016/09/30
産官学連携本部運営協議会 7号協議員 2015/04/01〜2017/03/31
産官学連携本部運営協議会 7号委員 2015/04/01〜2017/03/31
研究倫理・安全推進委員会 委員 2016/04/01〜
放射線同位元素等専門委員会 2015/04/01〜2017/03/31
情報ネットワーク倫理委員会 2011/04/01〜2013/03/31
組換えDNA実験安全委員会 1号委員 2016/10/01〜2018/09/30
国際高等教育院 企画評価専門委員会 初修外国語部会 委員 2013/07/18〜2015/04/30

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部局運営(役職等)
役職名 期間
医学研究科・医学部放射性同位元素等管理委員会 〜2017/03/31
医学部附属病院 臨床研究総合センター 副センター長 2013/04/01〜
医学部附属病院 臨床研究総合センター 開発企画部長 2013/04/01〜
寄附講座運営委員会(探索臨床腫瘍学) 2008/10/01〜2013/09/30
施設管理運営委員会 委員 〜2019/03/31
「次世代免疫制御を目指す創薬医学融合拠点」知財委員会 〜2015/09/30
「次世代免疫制御を目指す創薬医学融合拠点」開発推進委員会 〜2015/09/30
病院協議会 委員 2001/11/01〜2019/03/31
管理体制委員会 2012/10/01〜2014/09/30
附属ゲノム医学センター運営委員会 2010/04/01〜
iPS細胞臨床開発部運営委員会 〜2019/03/31
iPS等臨床試験センター整備専門委員会 〜2018/03/31
特定臨床研究実施管理委員会 〜2019/03/31
臨床研究総合センター協議会 〜2019/03/31
臨床研究総合センター運営委員会 〜2019/03/31
臨床研究総合センター推進委員会 〜2019/03/31
臨床研究総合センター医療開発委員会 〜2017/03/31
高齢者ユニット運営委員会 〜2017/03/31
予算委員会 〜2019/03/31
研究開発戦略推進委員会 2018/04/01〜
シーズ選定委員会 2018/04/01〜
研究開発連絡会(再生医療) 2018/04/01〜
研究開発連絡会(医療機器) 2018/04/01〜
研究開発連絡会(医薬品) 2018/04/01〜
放射線障害予防委員会 2017/04/01〜

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