Ayako Nagao, Minoru Kobayashi, Sho Koyasu, Christalle C T Chow, Hiroshi Harada |
Ayako Nagao, Minoru Kobayashi, Sho Koyasu, Christalle C T Chow, Hiroshi Harada |
Ayako Nagao, Minoru Kobayashi, Sho Koyasu, Christalle C T Chow, Hiroshi Harada |
HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance.  |
HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance.  |
HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance.  |
International journal of molecular sciences, 20, 2 |
International journal of molecular sciences, 20, 2 |
International journal of molecular sciences, 20, 2 |
2019/01/09 |
有 |
英語 |
|
公開 |
Koyasu S, Kobayashi M, Goto Y, Hiraoka M, Harada H |
Koyasu S, Kobayashi M, Goto Y, Hiraoka M, Harada H |
Koyasu S, Kobayashi M, Goto Y, Hiraoka M, Harada H |
Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge.  |
Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge.  |
Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge.  |
Cancer science, 109, 3, 560-571 |
Cancer science, 109, 3, 560-571 |
Cancer science, 109, 3, 560-571 |
2018/03 |
有 |
|
|
公開 |
Katagiri T, Kobayashi M, Yoshimura M, Morinibu A, Itasaka S, Hiraoka M, Harada H |
Katagiri T, Kobayashi M, Yoshimura M, Morinibu A, Itasaka S, Hiraoka M, Harada H |
Katagiri T, Kobayashi M, Yoshimura M, Morinibu A, Itasaka S, Hiraoka M, Harada H |
HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog. |
HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog. |
HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog. |
Oncotarget, 9, 12, 10525-10535 |
Oncotarget, 9, 12, 10525-10535 |
Oncotarget, 9, 12, 10525-10535 |
2018/02 |
有 |
|
|
公開 |
Kobayashi M, Morinibu A, Koyasu S, Goto Y, Hiraoka M, Harada H |
Kobayashi M, Morinibu A, Koyasu S, Goto Y, Hiraoka M, Harada H |
Minoru Kobayashi, Akiyo Morinibu, Sho Koyasu, Yoko Goto, Masahiro Hiraoka, Hiroshi Harada |
A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes. |
A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes. |
A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1 alpha to promoter regions of its downstream genes |
The FEBS journal, 284, 22, 3804-3816 |
The FEBS journal, 284, 22, 3804-3816 |
FEBS JOURNAL, 284, 22, 3804-3816 |
2017/11 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
Yoko Goto, Sho Koyasu, Minoru Kobayashi, Hiroshi Harada |
Yoko Goto, Sho Koyasu, Minoru Kobayashi, Hiroshi Harada |
Yoko Goto, Sho Koyasu, Minoru Kobayashi, Hiroshi Harada |
The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing strategies |
The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing strategies |
The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses, and antioxidant properties: Insight into the development of novel radiosensitizing strategies |
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 76-81 |
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 76-81 |
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 76-81 |
2017/10 |
有 |
英語 |
|
公開 |
Nakashima R, Goto Y, Koyasu S, Kobayashi M, Morinibu A, Yoshimura M, Hiraoka M, Hammond EM, Harada H |
Nakashima R, Goto Y, Koyasu S, Kobayashi M, Morinibu A, Yoshimura M, Hiraoka M, Hammond EM, Harada H |
Nakashima R, Goto Y, Koyasu S, Kobayashi M, Morinibu A, Yoshimura M, Hiraoka M, Hammond EM, Harada H |
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.  |
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.  |
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.  |
Scientific reports, 7, 1, 6879 |
Scientific reports, 7, 1, 6879 |
Scientific reports, 7, 1, 6879 |
2017/07 |
有 |
|
|
公開 |
Chan Joo Yeom, Lihua Zeng, Yoko Goto, Akiyo Morinibu, Yuxi Zhu, Kazumi Shinomiya, Minoru Kobayashi, Satoshi Itasaka, Michio Yoshimura, Cheol-Goo Hur, Hideaki Kakeya, Ester M. Hammond, Masahiro Hiraoka, Hiroshi Harada |
Chan Joo Yeom, Lihua Zeng, Yoko Goto, Akiyo Morinibu, Yuxi Zhu, Kazumi Shinomiya, Minoru Kobayashi, Satoshi Itasaka, Michio Yoshimura, Cheol-Goo Hur, Hideaki Kakeya, Ester M. Hammond, Masahiro Hiraoka, Hiroshi Harada |
Chan Joo Yeom, Lihua Zeng, Yoko Goto, Akiyo Morinibu, Yuxi Zhu, Kazumi Shinomiya, Minoru Kobayashi, Satoshi Itasaka, Michio Yoshimura, Cheol-Goo Hur, Hideaki Kakeya, Ester M. Hammond, Masahiro Hiraoka, Hiroshi Harada |
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis  |
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis  |
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis  |
ONCOTARGET, 7, 40, 65837-65848 |
ONCOTARGET, 7, 40, 65837-65848 |
ONCOTARGET, 7, 40, 65837-65848 |
2016/10 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
Minoru Inoue, Michio Yoshimura, Minoru Kobayashi, Akiyo Morinibu, Satoshi Itasaka, Masahiro Hiraoka, Hiroshi Harada |
Minoru Inoue, Michio Yoshimura, Minoru Kobayashi, Akiyo Morinibu, Satoshi Itasaka, Masahiro Hiraoka, Hiroshi Harada |
Minoru Inoue, Michio Yoshimura, Minoru Kobayashi, Akiyo Morinibu, Satoshi Itasaka, Masahiro Hiraoka, Hiroshi Harada |
PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase  |
PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase  |
PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase  |
SCIENTIFIC REPORTS, 5, 15666 |
SCIENTIFIC REPORTS, 5, 15666 |
SCIENTIFIC REPORTS, 5, 15666 |
2015/10 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
L. Zeng, A. Morinibu, M. Kobayashi, Y. Zhu, X. Wang, Y. Goto, C. J. Yeom, T. Zhao, K. Hirota, K. Shinomiya, S. Itasaka, M. Yoshimura, G. Guo, E. M. Hammond, M. Hiraoka, H. Harada |
|
L. Zeng, A. Morinibu, M. Kobayashi, Y. Zhu, X. Wang, Y. Goto, C. J. Yeom, T. Zhao, K. Hirota, K. Shinomiya, S. Itasaka, M. Yoshimura, G. Guo, E. M. Hammond, M. Hiraoka, H. Harada |
Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis. |
Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis. |
Aberrant IDH3 alpha expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis |
Oncogene., 34, 36, 4758-4766 |
Oncogene., 34, 36, 4758-4766 |
ONCOGENE, 34, 36, 4758-4766 |
2015/09 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
Goto Y, Zeng L, Yeom CJ, Zhu Y, Morinibu A, Shinomiya K, Kobayashi M, Hirota K, Itasaka S, Yoshimura M, Tanimoto K, Torii M, Sowa T, Menju T, Sonobe M, Kakeya H, Toi M, Date H, Hammond EM, Hiraoka M, Harada H |
Goto Y, Zeng L, Yeom CJ, Zhu Y, Morinibu A, Shinomiya K, Kobayashi M, Hirota K, Itasaka S, Yoshimura M, Tanimoto K, Torii M, Sowa T, Menju T, Sonobe M, Kakeya H, Toi M, Date H, Hammond EM, Hiraoka M, Harada H |
Yoko Goto, Lihua Zeng, Chan Joo Yeom, Yuxi Zhu, Akiyo Morinibu, Kazumi Shinomiya, Minoru Kobayashi, Kiichi Hirota, Satoshi Itasaka, Michio Yoshimura, Keiji Tanimoto, Masae Torii, Terumasa Sowa, Toshi Menju, Makoto Sonobe, Hideaki Kakeya, Masakazu Toi, Hiroshi Date, Ester M. Hammond, Masahiro Hiraoka, Hiroshi Harada |
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.  |
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.  |
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1 alpha  |
Nature Communications., 6, 6, 6153 |
Nature Communications., 6, 6, 6153 |
Nature Communications, 6, 6, 6153 |
2015/01 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
Tao Zhao, Yuxi Zhu, Akiyo Morinibu, Minoru Kobayashi, Kazumi Shinomiya, Satoshi Itasaka, Michio Yoshimura, Guozheng Guo, Masahiro Hiraoka, Hiroshi Harada |
Tao Zhao, Yuxi Zhu, Akiyo Morinibu, Minoru Kobayashi, Kazumi Shinomiya, Satoshi Itasaka, Michio Yoshimura, Guozheng Guo, Masahiro Hiraoka, Hiroshi Harada |
Tao Zhao, Yuxi Zhu, Akiyo Morinibu, Minoru Kobayashi, Kazumi Shinomiya, Satoshi Itasaka, Michio Yoshimura, Guozheng Guo, Masahiro Hiraoka, Hiroshi Harada |
HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs |
HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs |
HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs |
SCIENTIFIC REPORTS, 4, 4, 3793 |
SCIENTIFIC REPORTS, 4, 4, 3793 |
SCIENTIFIC REPORTS, 4, 4, 3793 |
2014/01 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
小林 稔, 原田 浩 |
小林 稔, 原田 浩 |
|
低酸素ストレスとHIF |
低酸素ストレスとHIF |
|
生化学, 85, 187 |
生化学, 85, 187 |
, 85, 187 |
2013 |
有 |
日本語 |
|
公開 |
Hidemitsu Kitamura, Minoru Kobayashi, Daiko Wakita, Takashi Nishimura |
Hidemitsu Kitamura, Minoru Kobayashi, Daiko Wakita, Takashi Nishimura |
Hidemitsu Kitamura, Minoru Kobayashi, Daiko Wakita, Takashi Nishimura |
Neuropeptide Signaling Activates Dendritic Cell-Mediated Type 1 Immune Responses through Neurokinin-2 Receptor |
Neuropeptide Signaling Activates Dendritic Cell-Mediated Type 1 Immune Responses through Neurokinin-2 Receptor |
Neuropeptide Signaling Activates Dendritic Cell-Mediated Type 1 Immune Responses through Neurokinin-2 Receptor |
JOURNAL OF IMMUNOLOGY, 188, 9, 4200-4208 |
JOURNAL OF IMMUNOLOGY, 188, 9, 4200-4208 |
JOURNAL OF IMMUNOLOGY, 188, 9, 4200-4208 |
2012/05 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
Minoru Kobayashi, Shigeru Ashino, Yasuo Shiohama, Daiko Wakita, Hidemitsu Kitamura, Takashi Nishimura |
Minoru Kobayashi, Shigeru Ashino, Yasuo Shiohama, Daiko Wakita, Hidemitsu Kitamura, Takashi Nishimura |
Minoru Kobayashi, Shigeru Ashino, Yasuo Shiohama, Daiko Wakita, Hidemitsu Kitamura, Takashi Nishimura |
IFN-gamma elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model |
IFN-gamma elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model |
IFN-gamma elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model |
EUROPEAN JOURNAL OF IMMUNOLOGY, 42, 2, 393-402 |
EUROPEAN JOURNAL OF IMMUNOLOGY, 42, 2, 393-402 |
EUROPEAN JOURNAL OF IMMUNOLOGY, 42, 2, 393-402 |
2012/02 |
有 |
英語 |
研究論文(学術雑誌) |
公開 |
西村 孝司, 小林 稔, 脇田 大功, 北村, 秀光, 芦野 茂 |
西村 孝司, 小林 稔, 脇田 大功, 北村, 秀光, 芦野 茂 |
|
Th17細胞による気道過敏反応の増強とその機序: Th1/Th2細胞依存的気道炎症との異同 |
Th17細胞による気道過敏反応の増強とその機序: Th1/Th2細胞依存的気道炎症との異同 |
|
臨床免疫・アレルギー科, 54, 631-638 |
臨床免疫・アレルギー科, 54, 631-638 |
, 54, 631-638 |
2010 |
有 |
日本語 |
|
公開 |