塚本 博丈

Last Update: 2021/06/02 23:50:13

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Name(Kanji/Kana/Abecedarium Latinum)
塚本 博丈/ツカモト ヒロタケ/Tsukamoto, Hirotake
Primary Affiliation(Org1/Job title)
Graduate Schools Medicine/Program-Specific Associate Professor
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 熊本大学
修士(理学) 熊本大学
Language of Instruction
Language(japanese) Language(english) Code
日本語 Japanese jpn
researchmap URL
https://researchmap.jp/read0126258
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Improved safety of induced pluripotent stem cell-derived antigen presenting cell-based cancer immunotherapy. Improved safety of induced pluripotent stem cell-derived antigen presenting cell-based cancer immunotherapy. Improved safety of induced pluripotent stem cell-derived antigen presenting cell-based cancer immunotherapy. Mol. Ther. Methods Clin. Dev. Mol. Ther. Methods Clin. Dev. Mol. Ther. Methods Clin. Dev. 2021/04 Refereed English Research paper(scientific journal) Disclose to all
Haruka Kuriyama, Satoshi Fukushima, Toshihiro Kimura, Hisashi Kanemaru, Azusa Miyashita, Etsuko Okada, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Yuki Nishimura, Ikko Kajihara, Katsunari Makino, Jun Aoi, Shinichi Masuguchi, Hirotake Tsukamoto, Takashi Inozume, Rong Zhang, Tetsuya Nakatsura, Yasushi Uemura, Satoru Senju, Hironobu Ihn Haruka Kuriyama, Satoshi Fukushima, Toshihiro Kimura, Hisashi Kanemaru, Azusa Miyashita, Etsuko Okada, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Yuki Nishimura, Ikko Kajihara, Katsunari Makino, Jun Aoi, Shinichi Masuguchi, Hirotake Tsukamoto, Takashi Inozume, Rong Zhang, Tetsuya Nakatsura, Yasushi Uemura, Satoru Senju, Hironobu Ihn Haruka Kuriyama, Satoshi Fukushima, Toshihiro Kimura, Hisashi Kanemaru, Azusa Miyashita, Etsuko Okada, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Yuki Nishimura, Ikko Kajihara, Katsunari Makino, Jun Aoi, Shinichi Masuguchi, Hirotake Tsukamoto, Takashi Inozume, Rong Zhang, Tetsuya Nakatsura, Yasushi Uemura, Satoru Senju, Hironobu Ihn Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma International Journal of Molecular Sciences, 22, 4, 1958-1958 International Journal of Molecular Sciences, 22, 4, 1958-1958 International Journal of Molecular Sciences, 22, 4, 1958-1958 2021/02/16 Refereed English Research paper(scientific journal) Disclose to all
Nakashima M, Ishikawa K, Fugiwara A, Shu K, Fukushima Y, Okamoto M, Tsukamoto H, Kouwaki T, Oshiumi H Nakashima M, Ishikawa K, Fugiwara A, Shu K, Fukushima Y, Okamoto M, Tsukamoto H, Kouwaki T, Oshiumi H Nakashima M, Ishikawa K, Fugiwara A, Shu K, Fukushima Y, Okamoto M, Tsukamoto H, Kouwaki T, Oshiumi H miR-451a levels rather than human papillomavirus vaccine administration is associated with the severity of murine experimental autoimmune encephalomyelitis. miR-451a levels rather than human papillomavirus vaccine administration is associated with the severity of murine experimental autoimmune encephalomyelitis. miR-451a levels rather than human papillomavirus vaccine administration is associated with the severity of murine experimental autoimmune encephalomyelitis. Scientific Reports Scientific Reports Scientific Reports 2021 Refereed English Research paper(scientific journal) Disclose to all
Tsukamoto H, Komohara Y, Oshiumi H Tsukamoto H, Komohara Y, Oshiumi H Tsukamoto H, Komohara Y, Oshiumi H The role of macrophages in anti-tumor immune responses: pathological significance and potential as therapeutic targets The role of macrophages in anti-tumor immune responses: pathological significance and potential as therapeutic targets The role of macrophages in anti-tumor immune responses: pathological significance and potential as therapeutic targets Human Cell Human Cell Human Cell 2021 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Takahisa Kouwaki, Hiroyuki Oshiumi Hirotake Tsukamoto, Takahisa Kouwaki, Hiroyuki Oshiumi Hirotake Tsukamoto, Takahisa Kouwaki, Hiroyuki Oshiumi Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly. Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly. Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly. iScience, 23, 9, 101520-101520 iScience, 23, 9, 101520-101520 iScience, 23, 9, 101520-101520 2020/09/01 Refereed English Research paper(scientific journal) Disclose to all
Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Mashima H, Zhang R, Kobayashi T, Hagiya Y, Tsukamoto H, Liu T, Iwama T, Nakatsuka R, Mishima Y, Okada S, Senju S, Takasu N, Kaneko S, Idiris A, Ohdan H, Nakatsura T, Uemura Y Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response OncoImmunology OncoImmunology OncoImmunology 2020/09 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka Yusuke Higuchi, Jun-Ichirou Yasunaga, Yu Mitagami, Hirotake Tsukamoto, Kazutaka Nakashima, Koichi Ohshima, Masao Matsuoka HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling. HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling. HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling. Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America 2020/05/29 Refereed English Research paper(scientific journal) Disclose to all
Toshihiro Kimura, Satoshi Fukushima, Etsuko Okada, Haruka Kuriyama, Hisashi Kanemaru, Mina Kadohisa-Tsuruta, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Ikko Kajihara, Katsunari Makino, Azusa Miyashita, Jun Aoi, Takamitsu Makino, Hirotake Tsukamoto, Yasuharu Nishimura, Takashi Inozume, Rong Zhang, Yasushi Uemura, Satoru Senju, Hironobu Ihn Toshihiro Kimura, Satoshi Fukushima, Etsuko Okada, Haruka Kuriyama, Hisashi Kanemaru, Mina Kadohisa-Tsuruta, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Ikko Kajihara, Katsunari Makino, Azusa Miyashita, Jun Aoi, Takamitsu Makino, Hirotake Tsukamoto, Yasuharu Nishimura, Takashi Inozume, Rong Zhang, Yasushi Uemura, Satoru Senju, Hironobu Ihn Toshihiro Kimura, Satoshi Fukushima, Etsuko Okada, Haruka Kuriyama, Hisashi Kanemaru, Mina Kadohisa-Tsuruta, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Ikko Kajihara, Katsunari Makino, Azusa Miyashita, Jun Aoi, Takamitsu Makino, Hirotake Tsukamoto, Yasuharu Nishimura, Takashi Inozume, Rong Zhang, Yasushi Uemura, Satoru Senju, Hironobu Ihn Induced pluripotent stem cell-derived myeloid cells expressing OX40 ligand amplify antigen-specific T cells in advanced melanoma. Induced pluripotent stem cell-derived myeloid cells expressing OX40 ligand amplify antigen-specific T cells in advanced melanoma. Induced pluripotent stem cell-derived myeloid cells expressing OX40 ligand amplify antigen-specific T cells in advanced melanoma. Pigment cell & melanoma research Pigment cell & melanoma research Pigment cell & melanoma research 2020/04/30 Refereed English Research paper(scientific journal) Disclose to all
Satoshi Umemoto, Miwa Haruta, Masataka Sakisaka, Tokunori Ikeda, Hirotake Tsukamoto, Yoshihiro Komohara, Motohiro Takeya, Yasuharu Nishimura, Satoru Senju Umemoto S, Haruta M, Sakisaka M, Ikeda T, Tsukamoto H, Komohara Y, Takeya M, Nishimura Y, Senju S Satoshi Umemoto, Miwa Haruta, Masataka Sakisaka, Tokunori Ikeda, Hirotake Tsukamoto, Yoshihiro Komohara, Motohiro Takeya, Yasuharu Nishimura, Satoru Senju Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells. Cancer therapy with MHC-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells. Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells. Cancer science, 110, 10, 3027-3037 Cancer science, 110, 10, 3027-3037 Cancer science, 110, 10, 3027-3037 2019/10 Refereed English Research paper(scientific journal) Disclose to all
Azusa Miyashita, Satoshi Fukushima, Hirotake Tsukamoto, Hisae Itai, Hideaki Miyamoto, Satoshi Nakahara, Yosuke Kubo, Toshihiro Kimura, Haruka Kuriyama, Hironobu Ihn Azusa Miyashita, Satoshi Fukushima, Hirotake Tsukamoto, Hisae Itai, Hideaki Miyamoto, Satoshi Nakahara, Yosuke Kubo, Toshihiro Kimura, Haruka Kuriyama, Hironobu Ihn Azusa Miyashita, Satoshi Fukushima, Hirotake Tsukamoto, Hisae Itai, Hideaki Miyamoto, Satoshi Nakahara, Yosuke Kubo, Toshihiro Kimura, Haruka Kuriyama, Hironobu Ihn Nivolumab-induced colitis in a patient with malignant melanoma: A case report and immunological analysis. Nivolumab-induced colitis in a patient with malignant melanoma: A case report and immunological analysis. Nivolumab-induced colitis in a patient with malignant melanoma: A case report and immunological analysis. The Journal of dermatology, 46, 9, e339-e341-e341 The Journal of dermatology, 46, 9, e339-e341-e341 The Journal of dermatology, 46, 9, e339-e341-e341 2019/09 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Koji Fujieda, Azusa Miyashita, Satoshi Fukushima, Tokunori Ikeda, Yosuke Kubo, Satoru Senju, Hironobu Ihn, Yasuharu Nishimura, Hiroyuki Oshiumi Hirotake Tsukamoto, Koji Fujieda, Azusa Miyashita, Satoshi Fukushima, Tokunori Ikeda, Yosuke Kubo, Satoru Senju, Hironobu Ihn, Yasuharu Nishimura, Hiroyuki Oshiumi Hirotake Tsukamoto, Koji Fujieda, Azusa Miyashita, Satoshi Fukushima, Tokunori Ikeda, Yosuke Kubo, Satoru Senju, Hironobu Ihn, Yasuharu Nishimura, Hiroyuki Oshiumi Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment. Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment. Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment. Cancer research, 78, 17, 5011-5022 Cancer research, 78, 17, 5011-5022 Cancer research, 78, 17, 5011-5022 2018/09/01 Refereed English Research paper(scientific journal) Disclose to all
Yoshimi Fukushima, Masaaki Okamoto, Kana Ishikawa, Takahisa Kouwaki, Hirotake Tsukamoto, Hiroyuki Oshiumi Yoshimi Fukushima, Masaaki Okamoto, Kana Ishikawa, Takahisa Kouwaki, Hirotake Tsukamoto, Hiroyuki Oshiumi Yoshimi Fukushima, Masaaki Okamoto, Kana Ishikawa, Takahisa Kouwaki, Hirotake Tsukamoto, Hiroyuki Oshiumi Activation of TLR3 and its adaptor TICAM-1 increases miR-21 levels in extracellular vesicles released from human cells Activation of TLR3 and its adaptor TICAM-1 increases miR-21 levels in extracellular vesicles released from human cells Activation of TLR3 and its adaptor TICAM-1 increases miR-21 levels in extracellular vesicles released from human cells Biochemical and Biophysical Research Communications, 500, 3, 744-750 Biochemical and Biophysical Research Communications, 500, 3, 744-750 Biochemical and Biophysical Research Communications, 500, 3, 744-750 2018/06/07 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Koji Fujieda, Satoru Senju, Tokunori Ikeda, Hiroyuki Oshiumi, Yasuharu Nishimura Hirotake Tsukamoto, Koji Fujieda, Satoru Senju, Tokunori Ikeda, Hiroyuki Oshiumi, Yasuharu Nishimura Hirotake Tsukamoto, Koji Fujieda, Satoru Senju, Tokunori Ikeda, Hiroyuki Oshiumi, Yasuharu Nishimura Immune-suppressive effects of interleukin-6 on T-cell-mediated anti-tumor immunity Immune-suppressive effects of interleukin-6 on T-cell-mediated anti-tumor immunity Immune-suppressive effects of interleukin-6 on T-cell-mediated anti-tumor immunity Cancer Science, 109, 3, 523-530 Cancer Science, 109, 3, 523-530 Cancer Science, 109, 3, 523-530 2018/03/01 Refereed English Research paper(scientific journal) Disclose to all
Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Misako Matsumoto, Tsukasa Seya, Hiroyuki Oshiumi Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Misako Matsumoto, Tsukasa Seya, Hiroyuki Oshiumi Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Misako Matsumoto, Tsukasa Seya, Hiroyuki Oshiumi Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response SCIENTIFIC REPORTS, 7, 1, 11905 SCIENTIFIC REPORTS, 7, 1, 11905 SCIENTIFIC REPORTS, 7, 1, 11905 2017/09 Refereed English Research paper(scientific journal) Disclose to all
Masaaki Okamoto, Hirotake Tsukamoto, Takahisa Kouwaki, Tsukasa Seya, Hiroyuki Oshiumi Masaaki Okamoto, Hirotake Tsukamoto, Takahisa Kouwaki, Tsukasa Seya, Hiroyuki Oshiumi Masaaki Okamoto, Hirotake Tsukamoto, Takahisa Kouwaki, Tsukasa Seya, Hiroyuki Oshiumi Recognition of Viral RNA by Pattern Recognition Receptors in the Induction of Innate Immunity and Excessive Inflammation During Respiratory Viral Infections Recognition of Viral RNA by Pattern Recognition Receptors in the Induction of Innate Immunity and Excessive Inflammation During Respiratory Viral Infections Recognition of Viral RNA by Pattern Recognition Receptors in the Induction of Innate Immunity and Excessive Inflammation During Respiratory Viral Infections VIRAL IMMUNOLOGY, 30, 6, 408-420 VIRAL IMMUNOLOGY, 30, 6, 408-420 VIRAL IMMUNOLOGY, 30, 6, 408-420 2017/07 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Koji Fujieda, Masatoshi Hirayama, Tokunori Ikeda, Akira Yuno, Keiko Matsumura, Daiki Fukuma, Kimi Araki, Hiroshi Mizuta, Hideki Nakayama, Satoru Senju, Yasuharu Nishimura Hirotake Tsukamoto, Koji Fujieda, Masatoshi Hirayama, Tokunori Ikeda, Akira Yuno, Keiko Matsumura, Daiki Fukuma, Kimi Araki, Hiroshi Mizuta, Hideki Nakayama, Satoru Senju, Yasuharu Nishimura Hirotake Tsukamoto, Koji Fujieda, Masatoshi Hirayama, Tokunori Ikeda, Akira Yuno, Keiko Matsumura, Daiki Fukuma, Kimi Araki, Hiroshi Mizuta, Hideki Nakayama, Satoru Senju, Yasuharu Nishimura Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression CANCER RESEARCH, 77, 9, 2279-2291 CANCER RESEARCH, 77, 9, 2279-2291 CANCER RESEARCH, 77, 9, 2279-2291 2017/05 Refereed English Research paper(scientific journal) Disclose to all
Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Hiroyuki Oshiumi Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Hiroyuki Oshiumi Takahisa Kouwaki, Masaaki Okamoto, Hirotake Tsukamoto, Yoshimi Fukushima, Hiroyuki Oshiumi Extracellular Vesicles Deliver Host and Virus RNA and Regulate Innate Immune Response Extracellular Vesicles Deliver Host and Virus RNA and Regulate Innate Immune Response Extracellular Vesicles Deliver Host and Virus RNA and Regulate Innate Immune Response INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18, 3 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18, 3 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18, 3 2017/03 Refereed English Disclose to all
Takanobu Motoshima, Yoshihiro Komohara, Hasita Horlad, Hirotake Tsukamoto, Mitsugu Fujita, Yoichi Saito, Kenichiro Tanoue, Yutaka Kasejima, Yutaka Sugiyama, Yoshiaki Kawano, Yasuharu Nishimura, Motohiro Takeya, Masatoshi Eto Takanobu Motoshima, Yoshihiro Komohara, Hasita Horlad, Hirotake Tsukamoto, Mitsugu Fujita, Yoichi Saito, Kenichiro Tanoue, Yutaka Kasejima, Yutaka Sugiyama, Yoshiaki Kawano, Yasuharu Nishimura, Motohiro Takeya, Masatoshi Eto Takanobu Motoshima, Yoshihiro Komohara, Hasita Horlad, Hirotake Tsukamoto, Mitsugu Fujita, Yoichi Saito, Kenichiro Tanoue, Yutaka Kasejima, Yutaka Sugiyama, Yoshiaki Kawano, Yasuharu Nishimura, Motohiro Takeya, Masatoshi Eto CXCL10 and CCL2 mRNA expression in monocytes is inversely correlated with the HLA-DR lower fraction of monocytes in patients with renal cell carcinoma CXCL10 and CCL2 mRNA expression in monocytes is inversely correlated with the HLA-DR lower fraction of monocytes in patients with renal cell carcinoma CXCL10 and CCL2 mRNA expression in monocytes is inversely correlated with the HLA-DR lower fraction of monocytes in patients with renal cell carcinoma ONCOLOGY LETTERS, 11, 3, 1911-1916 ONCOLOGY LETTERS, 11, 3, 1911-1916 ONCOLOGY LETTERS, 11, 3, 1911-1916 2016/03 Refereed English Research paper(scientific journal) Disclose to all
Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response Identification of glypican-3-derived long peptides activating both CD8(+) and CD4(+) T cells; prolonged overall survival in cancer patients with Th cell response ONCOIMMUNOLOGY, 5, 1, e1062209 ONCOIMMUNOLOGY, 5, 1, e1062209 ONCOIMMUNOLOGY, 5, 1, e1062209 2016 Refereed English Research paper(scientific journal) Disclose to all
Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Identification of glypican-3-derived long peptides activating both CD8+ and CD4+ T cells; prolonged overall survival in cancer patients with Th cell response Identification of glypican-3-derived long peptides activating both CD8+ and CD4+ T cells; prolonged overall survival in cancer patients with Th cell response Identification of glypican-3-derived long peptides activating both CD8+ and CD4+ T cells; prolonged overall survival in cancer patients with Th cell response OncoImmunology, 5, 1, e1062209 OncoImmunology, 5, 1, e1062209 OncoImmunology, 5, 1, e1062209 2016 Refereed English Research paper(scientific journal) Disclose to all
Masatoshi Hirayama, Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yuya Imamura, Mohammad Abu Sayem, Atsushi Irie, Yoshihiro Yoshitake, Daiki Fukuma, Masanori Shinohara, Akinobu Hamada, Hirofumi Jonof, Eiji Yuba, Kenji Kono, Koji Yoshida, Takuya Tsunoda, Hideki Nakayama, Yasuharu Nishimura Masatoshi Hirayama, Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yuya Imamura, Mohammad Abu Sayem, Atsushi Irie, Yoshihiro Yoshitake, Daiki Fukuma, Masanori Shinohara, Akinobu Hamada, Hirofumi Jonof, Eiji Yuba, Kenji Kono, Koji Yoshida, Takuya Tsunoda, Hideki Nakayama, Yasuharu Nishimura Masatoshi Hirayama, Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yuya Imamura, Mohammad Abu Sayem, Atsushi Irie, Yoshihiro Yoshitake, Daiki Fukuma, Masanori Shinohara, Akinobu Hamada, Hirofumi Jonof, Eiji Yuba, Kenji Kono, Koji Yoshida, Takuya Tsunoda, Hideki Nakayama, Yasuharu Nishimura An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs ONCOIMMUNOLOGY, 5, 6, e1123368 ONCOIMMUNOLOGY, 5, 6, e1123368 ONCOIMMUNOLOGY, 5, 6, e1123368 2016 Refereed English Research paper(scientific journal) Disclose to all
Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Mohammad A. Sayem, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Atsushi Irie, Hirotake Tsukamoto, Satoru Senju, Eiji Yuba, Toshiaki Yoshikawa, Kenji Kono, Tetsuya Nakatsura, Yasuharu Nishimura Efficient crosspresentation of oncofetal antigen (Glypican-3)-derived long peptides encompassing CTL and promiscuous Th cell epitopes using a novel liposome Efficient crosspresentation of oncofetal antigen (Glypican-3)-derived long peptides encompassing CTL and promiscuous Th cell epitopes using a novel liposome Efficient crosspresentation of oncofetal antigen (Glypican-3)-derived long peptides encompassing CTL and promiscuous Th cell epitopes using a novel liposome CANCER RESEARCH, 75 CANCER RESEARCH, 75 CANCER RESEARCH, 75 2015/08 Refereed English Disclose to all
Hirotake Tsukamoto, Satoru Senju, Keiko Matsumura, Susan L. Swain, Yasuharu Nishimura Hirotake Tsukamoto, Satoru Senju, Keiko Matsumura, Susan L. Swain, Yasuharu Nishimura Hirotake Tsukamoto, Satoru Senju, Keiko Matsumura, Susan L. Swain, Yasuharu Nishimura IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age NATURE COMMUNICATIONS, 6, 6702, 6702 NATURE COMMUNICATIONS, 6, 6702, 6702 NATURE COMMUNICATIONS, 6, 6702, 6702 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Tokunori Ikeda, Shinya Hirata, Koutaro Takamatsu, Miwa Haruta, Hirotake Tsukamoto, Takaaki Ito, Makoto Uchino, Yukio Ando, Seiho Nagafuchi, Yasuharu Nishimura, Satoru Senju Tokunori Ikeda, Shinya Hirata, Koutaro Takamatsu, Miwa Haruta, Hirotake Tsukamoto, Takaaki Ito, Makoto Uchino, Yukio Ando, Seiho Nagafuchi, Yasuharu Nishimura, Satoru Senju Tokunori Ikeda, Shinya Hirata, Koutaro Takamatsu, Miwa Haruta, Hirotake Tsukamoto, Takaaki Ito, Makoto Uchino, Yukio Ando, Seiho Nagafuchi, Yasuharu Nishimura, Satoru Senju Suppression of Th1-Mediated Autoimmunity by Embryonic Stem Cell-Derived Dendritic Cells Suppression of Th1-Mediated Autoimmunity by Embryonic Stem Cell-Derived Dendritic Cells Suppression of Th1-Mediated Autoimmunity by Embryonic Stem Cell-Derived Dendritic Cells PLOS ONE, 9, 12 PLOS ONE, 9, 12 PLOS ONE, 9, 12 2014/12 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Yuya Imamura, Junji Yatsuda, Mohammad Abu Sayem, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Yataro Daigo, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Yuya Imamura, Junji Yatsuda, Mohammad Abu Sayem, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Yataro Daigo, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Yuya Imamura, Junji Yatsuda, Mohammad Abu Sayem, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Yataro Daigo, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease Identification of immunogenic LY6K long peptide encompassing both CD4(+) and CD8(+) T-cell epitopes and eliciting CD4(+) T-cell immunity in patients with malignant disease ONCOIMMUNOLOGY, 3, 3, e28100 ONCOIMMUNOLOGY, 3, 3, e28100 ONCOIMMUNOLOGY, 3, 3, e28100 2014/03 Refereed English Research paper(scientific journal) Disclose to all
Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M. Irie A, Yatsuda J, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y, Nakamura Y, Shinohara M, Nishimura Y Tomita Y, Yuno A, Tsukamoto H, Senju S, Kuroda Y, Hirayama M. Irie A, Yatsuda J, Hamada A, Jono H, Yoshida K, Tsunoda T, Daigo Y, Kohrogi H, Yoshitake Y, Nakamura Y, Shinohara M, Nishimura Y LY6K-specific CD4+ T-cell immunity in patients with malignant tumor: Identification of LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes. LY6K-specific CD4+ T-cell immunity in patients with malignant tumor: Identification of LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes. Oncoimmunology Oncoimmunology 2014 Refereed Disclose to all
Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Sachiko Yoshimura, Ryuji Osawa, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Sachiko Yoshimura, Ryuji Osawa, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Sachiko Yoshimura, Ryuji Osawa, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Identification of CDCA1-derived long peptides bearing both CD4(+) and CD8(+) T-cell epitopes: CDCA1-specific CD4(+) T-cell immunity in cancer patients Identification of CDCA1-derived long peptides bearing both CD4(+) and CD8(+) T-cell epitopes: CDCA1-specific CD4(+) T-cell immunity in cancer patients Identification of CDCA1-derived long peptides bearing both CD4(+) and CD8(+) T-cell epitopes: CDCA1-specific CD4(+) T-cell immunity in cancer patients INTERNATIONAL JOURNAL OF CANCER, 134, 2, 352-366 INTERNATIONAL JOURNAL OF CANCER, 134, 2, 352-366 INTERNATIONAL JOURNAL OF CANCER, 134, 2, 352-366 2014/01 Refereed English Research paper(scientific journal) Disclose to all
Junji Yatsuda, Atsushi Irie, Kumiko Harada, Yayoi Michibata, Hirotake Tsukamoto, Satoru Senju, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Mohammad Abu Sayem, Naoki Takeda, Isao Shibuya, Shinji Sogo, Fumihiro Fujiki, Haruo Sugiyama, Masatoshi Eto, Yasuharu Nishimura Junji Yatsuda, Atsushi Irie, Kumiko Harada, Yayoi Michibata, Hirotake Tsukamoto, Satoru Senju, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Mohammad Abu Sayem, Naoki Takeda, Isao Shibuya, Shinji Sogo, Fumihiro Fujiki, Haruo Sugiyama, Masatoshi Eto, Yasuharu Nishimura Junji Yatsuda, Atsushi Irie, Kumiko Harada, Yayoi Michibata, Hirotake Tsukamoto, Satoru Senju, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Mohammad Abu Sayem, Naoki Takeda, Isao Shibuya, Shinji Sogo, Fumihiro Fujiki, Haruo Sugiyama, Masatoshi Eto, Yasuharu Nishimura Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens PLOS ONE, 8, 12 PLOS ONE, 8, 12 PLOS ONE, 8, 12 2013/12 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Kenta Kawahara, Junji Yatsuda, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Kenta Kawahara, Junji Yatsuda, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto, Satoru Senju, Yasuhiro Kuroda, Masatoshi Hirayama, Atsushi Irie, Kenta Kawahara, Junji Yatsuda, Akinobu Hamada, Hirofumi Jono, Koji Yoshida, Takuya Tsunoda, Hirotsugu Kohrogi, Yoshihiro Yoshitake, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4(+) and CD8(+) T-cell Epitopes: KIF20A-Specific CD4(+) T-cell Immunity in Patients with Malignant Tumor Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4(+) and CD8(+) T-cell Epitopes: KIF20A-Specific CD4(+) T-cell Immunity in Patients with Malignant Tumor Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4(+) and CD8(+) T-cell Epitopes: KIF20A-Specific CD4(+) T-cell Immunity in Patients with Malignant Tumor CLINICAL CANCER RESEARCH, 19, 16, 4508-4520 CLINICAL CANCER RESEARCH, 19, 16, 4508-4520 CLINICAL CANCER RESEARCH, 19, 16, 4508-4520 2013/08 English Research paper(scientific journal) Disclose to all
Hasita Horlad, Yukio Fujiwara, Kenichi Takemura, Koji Ohnishi, Tsuyoshi Ikeda, Hirotake Tsukamoto, Hiroshi Mizuta, Yasuharu Nishimura, Motohiro Takeya, Yoshihiro Komohara Hasita Horlad, Yukio Fujiwara, Kenichi Takemura, Koji Ohnishi, Tsuyoshi Ikeda, Hirotake Tsukamoto, Hiroshi Mizuta, Yasuharu Nishimura, Motohiro Takeya, Yoshihiro Komohara Hasita Horlad, Yukio Fujiwara, Kenichi Takemura, Koji Ohnishi, Tsuyoshi Ikeda, Hirotake Tsukamoto, Hiroshi Mizuta, Yasuharu Nishimura, Motohiro Takeya, Yoshihiro Komohara Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells Molecular Nutrition and Food Research, 57, 6, 1046-1054 Molecular Nutrition and Food Research, 57, 6, 1046-1054 Molecular Nutrition and Food Research, 57, 6, 1046-1054 2013/06 Refereed English Research paper(scientific journal) Disclose to all
Tsukamoto, H, Nishikata, R, Senju, S, Nishimura, Y Tsukamoto, H, Nishikata, R, Senju, S, Nishimura, Y Myeloid-derived suppressor cells attenuate TH1 development through IL-6 production to promote tumor progression. Myeloid-derived suppressor cells attenuate TH1 development through IL-6 production to promote tumor progression. Cancer Immunology Research Cancer Immunology Research 2013 Disclose to all
Hirotake Tsukamoto, Gail E. Huston, John Dibble, Debra K. Duso, Susan L. Swain Hirotake Tsukamoto, Gail E. Huston, John Dibble, Debra K. Duso, Susan L. Swain Hirotake Tsukamoto, Gail E. Huston, John Dibble, Debra K. Duso, Susan L. Swain Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects JOURNAL OF IMMUNOLOGY, 185, 8, 4535-4544 JOURNAL OF IMMUNOLOGY, 185, 8, 4535-4544 JOURNAL OF IMMUNOLOGY, 185, 8, 4535-4544 2010/10 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Karen Clise-Dwyer, Gail E. Huston, Debra K. Duso, Amanda L. Buck, Lawrence L. Johnson, Laura Haynes, Susan L. Swain Hirotake Tsukamoto, Karen Clise-Dwyer, Gail E. Huston, Debra K. Duso, Amanda L. Buck, Lawrence L. Johnson, Laura Haynes, Susan L. Swain Hirotake Tsukamoto, Karen Clise-Dwyer, Gail E. Huston, Debra K. Duso, Amanda L. Buck, Lawrence L. Johnson, Laura Haynes, Susan L. Swain Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106, 43, 18333-18338 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106, 43, 18333-18338 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106, 43, 18333-18338 2009/10 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Atsushi Irie, Satoru Senju, Antonis K. Hatzopoulos, Leszek Wojnowski, Yasuharu Nishimura Hirotake Tsukamoto, Atsushi Irie, Satoru Senju, Antonis K. Hatzopoulos, Leszek Wojnowski, Yasuharu Nishimura Hirotake Tsukamoto, Atsushi Irie, Satoru Senju, Antonis K. Hatzopoulos, Leszek Wojnowski, Yasuharu Nishimura B-Raf-mediated signaling pathway regulates T cell development B-Raf-mediated signaling pathway regulates T cell development B-Raf-mediated signaling pathway regulates T cell development EUROPEAN JOURNAL OF IMMUNOLOGY, 38, 2, 518-527 EUROPEAN JOURNAL OF IMMUNOLOGY, 38, 2, 518-527 EUROPEAN JOURNAL OF IMMUNOLOGY, 38, 2, 518-527 2008/02 Refereed English Research paper(scientific journal) Disclose to all
Atsushi Irie, Kumiko Harada, Hirotake Tsukamoto, Jeong-Ran Kim, Norie Araki, Yasuharu Nishimura Atsushi Irie, Kumiko Harada, Hirotake Tsukamoto, Jeong-Ran Kim, Norie Araki, Yasuharu Nishimura Atsushi Irie, Kumiko Harada, Hirotake Tsukamoto, Jeong-Ran Kim, Norie Araki, Yasuharu Nishimura Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells INTERNATIONAL IMMUNOLOGY, 18, 12, 1737-1747 INTERNATIONAL IMMUNOLOGY, 18, 12, 1737-1747 INTERNATIONAL IMMUNOLOGY, 18, 12, 1737-1747 2006/12 Refereed English Research paper(scientific journal) Disclose to all
Hirotake Tsukamoto, Atsushi Irie, Yu-Zhen Chen, Kumiko Takeshita, Jeong-Ran Kim, Yasuharu Nishimura Hirotake Tsukamoto, Atsushi Irie, Yu-Zhen Chen, Kumiko Takeshita, Jeong-Ran Kim, Yasuharu Nishimura Hirotake Tsukamoto, Atsushi Irie, Yu-Zhen Chen, Kumiko Takeshita, Jeong-Ran Kim, Yasuharu Nishimura TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4(+) T cell clone TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4(+) T cell clone TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4(+) T cell clone EUROPEAN JOURNAL OF IMMUNOLOGY, 36, 7, 1926-1937 EUROPEAN JOURNAL OF IMMUNOLOGY, 36, 7, 1926-1937 EUROPEAN JOURNAL OF IMMUNOLOGY, 36, 7, 1926-1937 2006/07 Refereed English Research paper(scientific journal) Disclose to all
S Hosaka, T Nakatsura, H Tsukamoto, T Hatayama, H Baba, Y Nishimura S Hosaka, T Nakatsura, H Tsukamoto, T Hatayama, H Baba, Y Nishimura S Hosaka, T Nakatsura, H Tsukamoto, T Hatayama, H Baba, Y Nishimura Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo CANCER SCIENCE, 97, 7, 623-632 CANCER SCIENCE, 97, 7, 623-632 CANCER SCIENCE, 97, 7, 623-632 2006/07 Refereed English Research paper(scientific journal) Disclose to all
Kim, JR, A Irie, H Tsukamoto, Y Nishimura Kim, JR, A Irie, H Tsukamoto, Y Nishimura Kim, JR, A Irie, H Tsukamoto, Y Nishimura A role of kinase inactive ZAP-70 in altered peptide ligand stimulated T cell activation A role of kinase inactive ZAP-70 in altered peptide ligand stimulated T cell activation A role of kinase inactive ZAP-70 in altered peptide ligand stimulated T cell activation BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 341, 1, 19-27 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 341, 1, 19-27 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 341, 1, 19-27 2006/03 Refereed English Research paper(scientific journal) Disclose to all
H Tsukamoto, A Irie, Y Nishimura H Tsukamoto, A Irie, Y Nishimura H Tsukamoto, A Irie, Y Nishimura B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 46, 48457-48465 JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 46, 48457-48465 JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 46, 48457-48465 2004/11 Refereed English Research paper(scientific journal) Disclose to all
Yoshihiro Yoshitake, Tetsuya Nakatsura, Mikio Monji, Satoru Senju, Hidetake Matsuyoshi, Hirotake Tsukamoto, Seiji Hosaka, Hiroyuki Komori, Daiki Fukuma, Yoshiaki Ikuta, Toyomasa Katagiri, Yoichi Furukawa, Hiromi Ito, Masanori Shinohara, Yusuke Nakamura, Yasuharu Nishimura Yoshihiro Yoshitake, Tetsuya Nakatsura, Mikio Monji, Satoru Senju, Hidetake Matsuyoshi, Hirotake Tsukamoto, Seiji Hosaka, Hiroyuki Komori, Daiki Fukuma, Yoshiaki Ikuta, Toyomasa Katagiri, Yoichi Furukawa, Hiromi Ito, Masanori Shinohara, Yusuke Nakamura, Yasuharu Nishimura Yoshihiro Yoshitake, Tetsuya Nakatsura, Mikio Monji, Satoru Senju, Hidetake Matsuyoshi, Hirotake Tsukamoto, Seiji Hosaka, Hiroyuki Komori, Daiki Fukuma, Yoshiaki Ikuta, Toyomasa Katagiri, Yoichi Furukawa, Hiromi Ito, Masanori Shinohara, Yusuke Nakamura, Yasuharu Nishimura Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis Clinical Cancer Research, 10, 19, 6437-6448 Clinical Cancer Research, 10, 19, 6437-6448 Clinical Cancer Research, 10, 19, 6437-6448 2004/10/01 Refereed English Research paper(scientific journal) Disclose to all
Y Nishimura, YZ Chen, Y Uemura, Y Tanaka, H Tsukamoto, T Kanai, H Yokomizo, C Yun, T Matsuoka, A Irie, S Matsushita Y Nishimura, YZ Chen, Y Uemura, Y Tanaka, H Tsukamoto, T Kanai, H Yokomizo, C Yun, T Matsuoka, A Irie, S Matsushita Y Nishimura, YZ Chen, Y Uemura, Y Tanaka, H Tsukamoto, T Kanai, H Yokomizo, C Yun, T Matsuoka, A Irie, S Matsushita Degenerate recognition and response of human CD4(+) Th cell clones: implications for basic and applied immunology Degenerate recognition and response of human CD4(+) Th cell clones: implications for basic and applied immunology Degenerate recognition and response of human CD4(+) Th cell clones: implications for basic and applied immunology MOLECULAR IMMUNOLOGY, 40, 14-15, 1089-1094 MOLECULAR IMMUNOLOGY, 40, 14-15, 1089-1094 MOLECULAR IMMUNOLOGY, 40, 14-15, 1089-1094 2004/02 Refereed English Research paper(scientific journal) Disclose to all
A Irie, YZ Chen, H Tsukamoto, T Jotsuka, M Masuda, Y Nishimura A Irie, YZ Chen, H Tsukamoto, T Jotsuka, M Masuda, Y Nishimura A Irie, YZ Chen, H Tsukamoto, T Jotsuka, M Masuda, Y Nishimura Unique T cell proliferation associated with PKC mu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes Unique T cell proliferation associated with PKC mu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes Unique T cell proliferation associated with PKC mu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes EUROPEAN JOURNAL OF IMMUNOLOGY, 33, 6, 1497-1507 EUROPEAN JOURNAL OF IMMUNOLOGY, 33, 6, 1497-1507 EUROPEAN JOURNAL OF IMMUNOLOGY, 33, 6, 1497-1507 2003/06 Refereed English Research paper(scientific journal) Disclose to all
Y Uemura, S Senju, K Maenaka, LK Iwai, S Fujii, H Tabata, H Tsukamoto, S Hirata, YZ Chen, Y Nishimura Y Uemura, S Senju, K Maenaka, LK Iwai, S Fujii, H Tabata, H Tsukamoto, S Hirata, YZ Chen, Y Nishimura Y Uemura, S Senju, K Maenaka, LK Iwai, S Fujii, H Tabata, H Tsukamoto, S Hirata, YZ Chen, Y Nishimura Systematic analysis of the combinatorial nature of epitopes recognized by TCR leads to identification of mimicry epitopes for glutamic acid decarboxylase 65-specific TCRs Systematic analysis of the combinatorial nature of epitopes recognized by TCR leads to identification of mimicry epitopes for glutamic acid decarboxylase 65-specific TCRs Systematic analysis of the combinatorial nature of epitopes recognized by TCR leads to identification of mimicry epitopes for glutamic acid decarboxylase 65-specific TCRs JOURNAL OF IMMUNOLOGY, 170, 2, 947-960 JOURNAL OF IMMUNOLOGY, 170, 2, 947-960 JOURNAL OF IMMUNOLOGY, 170, 2, 947-960 2003/01 Refereed English Research paper(scientific journal) Disclose to all
T Yamane, T Kunisada, H Tsukamoto, H Yamazaki, H Niwa, S Takada, SI Hayashi T Yamane, T Kunisada, H Tsukamoto, H Yamazaki, H Niwa, S Takada, SI Hayashi T Yamane, T Kunisada, H Tsukamoto, H Yamazaki, H Niwa, S Takada, SI Hayashi Wnt signaling regulates hemopoiesis through stromal cells Wnt signaling regulates hemopoiesis through stromal cells Wnt signaling regulates hemopoiesis through stromal cells JOURNAL OF IMMUNOLOGY, 167, 2, 765-772 JOURNAL OF IMMUNOLOGY, 167, 2, 765-772 JOURNAL OF IMMUNOLOGY, 167, 2, 765-772 2001/07 Refereed English Research paper(scientific journal) Disclose to all

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