髙倉 喜信

Last Update: 2021/06/10 10:52:05

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Name(Kanji/Kana/Abecedarium Latinum)
髙倉 喜信/タカクラ ヨシノブ/Takakura, Yoshinobu
Primary Affiliation(Org1/Job title)
Graduate Schools Pharmaceutical Sciences/Professor
Faculty
Org1 Job title
薬学部
Contact Address
Type Address(Japanese) Address(English)
Office 京都市左京区吉田下阿達町46-29
Phone
Type Number
Office 075-753-4615
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
日本薬学会
日本薬剤学会
日本薬物動態学会
日本DDS学会
日本癌学会
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
薬学修士 京都大学
薬学博士 京都大学
Academic Resume (Graduate Schools)
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(Japanese) Major(English) Completion Status
京都大学 大学院薬学研究科修士課程薬学専攻 修了
Academic Resume (Undergraduate School/Majors)
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(s)(Japanese) Major(s)(English) Completion Status
京都大学 薬学部薬学科 卒業
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
-
Language of Instruction
Language(japanese) Language(english) Code
英語 English eng
ORCID ID
https://orcid.org/0000-0002-7359-2647
researchmap URL
https://researchmap.jp/read0013267
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Aki Yamamoto, Yukari Yasue, Yuki Takahashi, Yoshinobu Takakura Aki Yamamoto, Yukari Yasue, Yuki Takahashi, Yoshinobu Takakura Aki Yamamoto, Yukari Yasue, Yuki Takahashi, Yoshinobu Takakura Determining the role of surface glycans in the pharmacokinetics of small extracellular vesicles. Determining the role of surface glycans in the pharmacokinetics of small extracellular vesicles. Determining the role of surface glycans in the pharmacokinetics of small extracellular vesicles. Journal of pharmaceutical sciences Journal of pharmaceutical sciences Journal of pharmaceutical sciences 2021/06/03 English Research paper(scientific journal) Disclose to all
Keisuke Umemura, Shozo Ohtsuki, Makoto Nagaoka, Kosuke Kusamori, Takao Inoue, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Keisuke Umemura, Shozo Ohtsuki, Makoto Nagaoka, Kosuke Kusamori, Takao Inoue, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Keisuke Umemura, Shozo Ohtsuki, Makoto Nagaoka, Kosuke Kusamori, Takao Inoue, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells. Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells. Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells. Nanomedicine : nanotechnology, biology, and medicine, 34, 102386-102386 Nanomedicine : nanotechnology, biology, and medicine, 34, 102386-102386 Nanomedicine : nanotechnology, biology, and medicine, 34, 102386-102386 2021/03/24 English Research paper(scientific journal) Disclose to all
Yuki Araie, Shozo Ohtsuki, Soyoung Park, Makoto Nagaoka, Keisuke Umemura, Hiroshi Sugiyama, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuki Araie, Shozo Ohtsuki, Soyoung Park, Makoto Nagaoka, Keisuke Umemura, Hiroshi Sugiyama, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuki Araie, Shozo Ohtsuki, Soyoung Park, Makoto Nagaoka, Keisuke Umemura, Hiroshi Sugiyama, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide. Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide. Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide. Bioorganic & medicinal chemistry, 29, 115864-115864 Bioorganic & medicinal chemistry, 29, 115864-115864 Bioorganic & medicinal chemistry, 29, 115864-115864 2021/01/01 English Research paper(scientific journal) Disclose to all
Misako Takenaka, Yuki Takahashi, Yoshinobu Takakura Misako Takenaka, Yuki Takahashi, Yoshinobu Takakura Misako Takenaka, Yuki Takahashi, Yoshinobu Takakura Intercellular delivery of NF-κB inhibitor peptide utilizing small extracellular vesicles for the application of anti-inflammatory therapy. Intercellular delivery of NF-κB inhibitor peptide utilizing small extracellular vesicles for the application of anti-inflammatory therapy. Intercellular delivery of NF-κB inhibitor peptide utilizing small extracellular vesicles for the application of anti-inflammatory therapy. Journal of controlled release : official journal of the Controlled Release Society, 328, 435-443 Journal of controlled release : official journal of the Controlled Release Society, 328, 435-443 Journal of controlled release : official journal of the Controlled Release Society, 328, 435-443 2020/12/10 English Research paper(scientific journal) Disclose to all
Akihiro Matsumoto, Maho Asuka, Yuki Takahashi, Yoshinobu Takakura Akihiro Matsumoto, Maho Asuka, Yuki Takahashi, Yoshinobu Takakura Akihiro Matsumoto, Maho Asuka, Yuki Takahashi, Yoshinobu Takakura Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses. Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses. Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses. Biomaterials, 252, 120112-120112 Biomaterials, 252, 120112-120112 Biomaterials, 252, 120112-120112 2020/09 Refereed English Research paper(scientific journal) Disclose to all
Tatsuoki Maezawa, Shozo Ohtsuki, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tatsuoki Maezawa, Shozo Ohtsuki, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tatsuoki Maezawa, Shozo Ohtsuki, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells. DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells. DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells. Nanoscale, 12, 27, 14818-14824 Nanoscale, 12, 27, 14818-14824 Nanoscale, 12, 27, 14818-14824 2020/07/16 Refereed English Research paper(scientific journal) Disclose to all
Wen Liu, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Wen Liu, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Wen Liu, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response. Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response. Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response. Nanomedicine (London, England) Nanomedicine (London, England) Nanomedicine (London, England) 2020/07/15 Refereed English Research paper(scientific journal) Disclose to all
Yuto Nakamura, Shunbun Kita, Yoshimitsu Tanaka, Shiro Fukuda, Yoshinari Obata, Tomonori Okita, Hiroyuki Nishida, Yuki Takahashi, Yusuke Kawachi, Yuri Tsugawa-Shimizu, Yuya Fujishima, Hitoshi Nishizawa, Yoshinobu Takakura, Shigeru Miyagawa, Yoshiki Sawa, Norikazu Maeda, Iichiro Shimomura Yuto Nakamura, Shunbun Kita, Yoshimitsu Tanaka, Shiro Fukuda, Yoshinari Obata, Tomonori Okita, Hiroyuki Nishida, Yuki Takahashi, Yusuke Kawachi, Yuri Tsugawa-Shimizu, Yuya Fujishima, Hitoshi Nishizawa, Yoshinobu Takakura, Shigeru Miyagawa, Yoshiki Sawa, Norikazu Maeda, Iichiro Shimomura Yuto Nakamura, Shunbun Kita, Yoshimitsu Tanaka, Shiro Fukuda, Yoshinari Obata, Tomonori Okita, Hiroyuki Nishida, Yuki Takahashi, Yusuke Kawachi, Yuri Tsugawa-Shimizu, Yuya Fujishima, Hitoshi Nishizawa, Yoshinobu Takakura, Shigeru Miyagawa, Yoshiki Sawa, Norikazu Maeda, Iichiro Shimomura Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice. Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice. Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice. Molecular therapy : the journal of the American Society of Gene Therapy Molecular therapy : the journal of the American Society of Gene Therapy Molecular therapy : the journal of the American Society of Gene Therapy 2020/07/08 Refereed English Research paper(scientific journal) Disclose to all
Wenqing Liao, Mengmeng Tan, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Wenqing Liao, Mengmeng Tan, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Wenqing Liao, Mengmeng Tan, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Construction of Monomeric and Dimeric G-Quadruplex-Structured Cytosine-Phosphate-Guanine Oligodeoxynucleotides for Enhanced Uptake and Activation in Toll-Like Receptor 9-Positive Macrophages. Construction of Monomeric and Dimeric G-Quadruplex-Structured Cytosine-Phosphate-Guanine Oligodeoxynucleotides for Enhanced Uptake and Activation in Toll-Like Receptor 9-Positive Macrophages. Construction of Monomeric and Dimeric G-Quadruplex-Structured Cytosine-Phosphate-Guanine Oligodeoxynucleotides for Enhanced Uptake and Activation in Toll-Like Receptor 9-Positive Macrophages. Nucleic acid therapeutics Nucleic acid therapeutics Nucleic acid therapeutics 2020/06/22 Refereed English Research paper(scientific journal) Disclose to all
Fusae Komura, Kana Okuzumi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Fusae Komura, Kana Okuzumi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Fusae Komura, Kana Okuzumi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation. Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation. Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation. Molecules (Basel, Switzerland), 25, 3 Molecules (Basel, Switzerland), 25, 3 Molecules (Basel, Switzerland), 25, 3 2020/02/07 Refereed English Research paper(scientific journal) Disclose to all
Mengmeng Tan, Natsuki Takahashi, Shota Fujii, Kazuo Sakurai, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Mengmeng Tan, Natsuki Takahashi, Shota Fujii, Kazuo Sakurai, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Mengmeng Tan, Natsuki Takahashi, Shota Fujii, Kazuo Sakurai, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Analysis of Tertiary Structural Features of Branched DNA Nanostructures with Partially Common Sequences Using Small-Angle X-ray Scattering Analysis of Tertiary Structural Features of Branched DNA Nanostructures with Partially Common Sequences Using Small-Angle X-ray Scattering Analysis of Tertiary Structural Features of Branched DNA Nanostructures with Partially Common Sequences Using Small-Angle X-ray Scattering ACS Applied Bio Materials, 3, 1, 308-314 ACS Applied Bio Materials, 3, 1, 308-314 ACS Applied Bio Materials, 3, 1, 308-314 2020/01/21 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Akihiro Matsumoto, Yuki Takahashi Yoshinobu Takakura, Akihiro Matsumoto, Yuki Takahashi Yoshinobu Takakura, Akihiro Matsumoto, Yuki Takahashi Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges. Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges. Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges. Biological & pharmaceutical bulletin, 43, 4, 576-583 Biological & pharmaceutical bulletin, 43, 4, 576-583 Biological & pharmaceutical bulletin, 43, 4, 576-583 2020 Refereed English Research paper(scientific journal) Disclose to all
Yuya Mizukami, Ai Moriya, Yuki Takahashi, Kazunori Shimizu, Satoshi Konishi, Yoshinobu Takakura, Makiya Nishikawa Yuya Mizukami, Ai Moriya, Yuki Takahashi, Kazunori Shimizu, Satoshi Konishi, Yoshinobu Takakura, Makiya Nishikawa Yuya Mizukami, Ai Moriya, Yuki Takahashi, Kazunori Shimizu, Satoshi Konishi, Yoshinobu Takakura, Makiya Nishikawa Incorporation of gelatin microspheres into HepG2 human hepatocyte spheroids for functional improvement through improved oxygen supply to spheroid core Incorporation of gelatin microspheres into HepG2 human hepatocyte spheroids for functional improvement through improved oxygen supply to spheroid core Incorporation of gelatin microspheres into HepG2 human hepatocyte spheroids for functional improvement through improved oxygen supply to spheroid core Biological and Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 2020 Refereed English Research paper(scientific journal) Disclose to all
Wenqing Liao, Sakiko Akahira, Rintaro, Iwata Hara, Takeshi Wada, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Wenqing Liao, Sakiko Akahira, Rintaro, Iwata Hara, Takeshi Wada, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Wenqing Liao, Sakiko Akahira, Rintaro, Iwata Hara, Takeshi Wada, Kosuke Kusamori, Yoshinobu Takakura, Makiya Nishikawa Enhanced Immunostimulatory Activity of CpG Oligodeoxynucleotide by the Combination of Mannose Modification and Incorporation into Nanostructured DNA Enhanced Immunostimulatory Activity of CpG Oligodeoxynucleotide by the Combination of Mannose Modification and Incorporation into Nanostructured DNA Enhanced Immunostimulatory Activity of CpG Oligodeoxynucleotide by the Combination of Mannose Modification and Incorporation into Nanostructured DNA Biological and Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 2020 Refereed English Research paper(scientific journal) Disclose to all
Matsumoto A, Takahashi Y, Chang HY, Wu YW, Yamamoto A, Ishihama Y, Takakura Y Matsumoto A, Takahashi Y, Chang HY, Wu YW, Yamamoto A, Ishihama Y, Takakura Y Matsumoto A, Takahashi Y, Chang HY, Wu YW, Yamamoto A, Ishihama Y, Takakura Y Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance. Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance. Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance. Journal of extracellular vesicles, 9, 1, 1696517 Journal of extracellular vesicles, 9, 1, 1696517 Journal of extracellular vesicles, 9, 1, 1696517 2020 Refereed Disclose to all
Matsumoto A, Takahashi Y, Ariizumi R, Nishikawa M, Takakura Y Matsumoto A, Takahashi Y, Ariizumi R, Nishikawa M, Takakura Y Matsumoto A, Takahashi Y, Ariizumi R, Nishikawa M, Takakura Y Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells. Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells. Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells. Biomaterials, 225, 119518 Biomaterials, 225, 119518 Biomaterials, 225, 119518 2019/12 Refereed Disclose to all
Arima Y, Liu W, Takahashi Y, Nishikawa M, Takakura Y Arima Y, Liu W, Takahashi Y, Nishikawa M, Takakura Y Arima Y, Liu W, Takahashi Y, Nishikawa M, Takakura Y Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation. Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation. Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation. Molecular pharmaceutics, 16, 6, 2309-2314 Molecular pharmaceutics, 16, 6, 2309-2314 Molecular pharmaceutics, 16, 6, 2309-2314 2019/06 Refereed English Disclose to all
Ippei Takashima, Kosuke Kusamori, Hayase Hakariya, Megumi Takashima, Thi Hue Vu, Yuya Mizukami, Naotaka Noda, Yukiya Takayama, Yousuke Katsuda, Shin-ichi Sato, Yoshinobu Takakura, Makiya Nishikawa, Motonari Uesugi Ippei Takashima, Kosuke Kusamori, Hayase Hakariya, Megumi Takashima, Thi Hue Vu, Yuya Mizukami, Naotaka Noda, Yukiya Takayama, Yousuke Katsuda, Shin-ichi Sato, Yoshinobu Takakura, Makiya Nishikawa, Motonari Uesugi Ippei Takashima, Kosuke Kusamori, Hayase Hakariya, Megumi Takashima, Thi Hue Vu, Yuya Mizukami, Naotaka Noda, Yukiya Takayama, Yousuke Katsuda, Shin-ichi Sato, Yoshinobu Takakura, Makiya Nishikawa, Motonari Uesugi Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment Multifunctionalization of Cells with a Self-Assembling Molecule to Enhance Cell Engraftment ACS Chemical Biology, 14, 4, 775-783 ACS Chemical Biology, 14, 4, 775-783 ACS Chemical Biology, 14, 4, 775-783 2019/04/19 Refereed English Research paper(scientific journal) Disclose to all
Chonlada Charoenviriyakul, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Erratum to 'Preservation of exosomes at room temperature using lyophilization' [International Journal of Pharmaceutics 553 (2018) 1-7]. Erratum to 'Preservation of exosomes at room temperature using lyophilization' [International Journal of Pharmaceutics 553 (2018) 1-7]. Erratum to 'Preservation of exosomes at room temperature using lyophilization' [International Journal of Pharmaceutics 553 (2018) 1-7]. International journal of pharmaceutics, 559, 427-428 International journal of pharmaceutics, 559, 427-428 International journal of pharmaceutics, 559, 427-428 2019/03/25 English Research paper(scientific journal) Disclose to all
S. Ohtsuki, Y. Shiba, T. Maezawa, K. Hidaka, H. Sugiyama, M. Endo, Y. Takahashi, Y. Takakura, M. Nishikawa S. Ohtsuki, Y. Shiba, T. Maezawa, K. Hidaka, H. Sugiyama, M. Endo, Y. Takahashi, Y. Takakura, M. Nishikawa S. Ohtsuki, Y. Shiba, T. Maezawa, K. Hidaka, H. Sugiyama, M. Endo, Y. Takahashi, Y. Takakura, M. Nishikawa Folding of single-stranded circular DNA into rigid rectangular DNA accelerates its cellular uptake. Folding of single-stranded circular DNA into rigid rectangular DNA accelerates its cellular uptake. Folding of single-stranded circular DNA into rigid rectangular DNA accelerates its cellular uptake. Nanoscale, 11, 23416-23422 Nanoscale, 11, 23416-23422 Nanoscale, 11, 23416-23422 2019/03 Refereed Disclose to all
Mizukami Y, Takahashi Y, Shimizu K, Konishi S, Takakura Y, Nishikawa M Mizukami Y, Takahashi Y, Shimizu K, Konishi S, Takakura Y, Nishikawa M Mizukami Y, Takahashi Y, Shimizu K, Konishi S, Takakura Y, Nishikawa M Regulation of the Distribution of Cells in Mixed Spheroids by Altering Migration Direction. Regulation of the Distribution of Cells in Mixed Spheroids by Altering Migration Direction. Regulation of the Distribution of Cells in Mixed Spheroids by Altering Migration Direction. Tissue engineering. Part A, 25, 5-6, 390-398 Tissue engineering. Part A, 25, 5-6, 390-398 Tissue engineering. Part A, 25, 5-6, 390-398 2019/03 Refereed English Disclose to all
Komura F, Takahashi Y, Inoue T, Takakura Y, Nishikawa M Komura F, Takahashi Y, Inoue T, Takakura Y, Nishikawa M Komura F, Takahashi Y, Inoue T, Takakura Y, Nishikawa M Development of a nanostructured RNA/DNA assembly as an adjuvant targeting Toll-like receptor 7/8. Development of a nanostructured RNA/DNA assembly as an adjuvant targeting Toll-like receptor 7/8. Development of a nanostructured RNA/DNA assembly as an adjuvant targeting Toll-like receptor 7/8. NUCLEIC ACID THER NUCLEIC ACID THER NUCLEIC ACID THER 2019 Refereed English Disclose to all
Charoenviriyakul C, Takahashi Y, Nishikawa M, Takakura Y Charoenviriyakul C, Takahashi Y, Nishikawa M, Takakura Y Charoenviriyakul C, Takahashi Y, Nishikawa M, Takakura Y Preservation of exosomes at room temperature using lyophilization. Preservation of exosomes at room temperature using lyophilization. Preservation of exosomes at room temperature using lyophilization. International journal of pharmaceutics, 553, 1-2, 1-7 International journal of pharmaceutics, 553, 1-2, 1-7 International journal of pharmaceutics, 553, 1-2, 1-7 2018/12 Refereed English Disclose to all
Umeki Y, Saito M, Kusamori K, Tsujimura M, Nishimura M, Takahashi Y, Takakura Y, Nishikawa M Umeki Y, Saito M, Kusamori K, Tsujimura M, Nishimura M, Takahashi Y, Takakura Y, Nishikawa M Umeki Y, Saito M, Kusamori K, Tsujimura M, Nishimura M, Takahashi Y, Takakura Y, Nishikawa M Combined encapsulation of a tumor antigen and immune cells using a self-assembling immunostimulatory DNA hydrogel to enhance antigen-specific tumor immunity. Combined encapsulation of a tumor antigen and immune cells using a self-assembling immunostimulatory DNA hydrogel to enhance antigen-specific tumor immunity. Combined encapsulation of a tumor antigen and immune cells using a self-assembling immunostimulatory DNA hydrogel to enhance antigen-specific tumor immunity. Journal of controlled release : official journal of the Controlled Release Society, 288, 189-198 Journal of controlled release : official journal of the Controlled Release Society, 288, 189-198 Journal of controlled release : official journal of the Controlled Release Society, 288, 189-198 2018/10 Refereed English Disclose to all
Daiki Nomura, Masaaki Saito, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Daiki Nomura, Masaaki Saito, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Daiki Nomura, Masaaki Saito, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating International Journal of Pharmaceutics, 547, 1-2, 556-562 International Journal of Pharmaceutics, 547, 1-2, 556-562 International Journal of Pharmaceutics, 547, 1-2, 556-562 2018/08/25 Refereed English Research paper(scientific journal) Disclose to all
Takuma Yamashita, Yuki Takahashi, Yoshinobu Takakura Takuma Yamashita, Yuki Takahashi, Yoshinobu Takakura Takuma Yamashita, Yuki Takahashi, Yoshinobu Takakura Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application Biological and Pharmaceutical Bulletin, 41, 6, 835-842 Biological and Pharmaceutical Bulletin, 41, 6, 835-842 Biological and Pharmaceutical Bulletin, 41, 6, 835-842 2018/06/01 Refereed English Research paper(scientific journal) Disclose to all
Yosuke Takahashi, Yuki Araie, Daiki Nomura, Yuki Takahashi, Kohei Sano, Hideo Saji, Yoshinobu Takakura, Makiya Nishikawa Yosuke Takahashi, Yuki Araie, Daiki Nomura, Yuki Takahashi, Kohei Sano, Hideo Saji, Yoshinobu Takakura, Makiya Nishikawa Yosuke Takahashi, Yuki Araie, Daiki Nomura, Yuki Takahashi, Kohei Sano, Hideo Saji, Yoshinobu Takakura, Makiya Nishikawa Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice Journal of Drug Targeting, 26, 4, 373-381 Journal of Drug Targeting, 26, 4, 373-381 Journal of Drug Targeting, 26, 4, 373-381 2018/04/21 Refereed English Research paper(scientific journal) Disclose to all
Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Makiya Nishikawa, Yoshinobu Takakura Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles. Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles. Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles. Molecular pharmaceutics, 15, 3, 1073-1080 Molecular pharmaceutics, 15, 3, 1073-1080 Molecular pharmaceutics, 15, 3, 1073-1080 2018/03/05 Refereed English Disclose to all
Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins International Journal of Pharmaceutics, 536, 1, 310-317 International Journal of Pharmaceutics, 536, 1, 310-317 International Journal of Pharmaceutics, 536, 1, 310-317 2018/01/30 Refereed English Research paper(scientific journal) Disclose to all
Yutaro Tanaka, Makiya Nishikawa, Yuya Mizukami, Kosuke Kusamori, Yuka Ogino, Shunsuke Nishimura, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Yutaro Tanaka, Makiya Nishikawa, Yuya Mizukami, Kosuke Kusamori, Yuka Ogino, Shunsuke Nishimura, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Yutaro Tanaka, Makiya Nishikawa, Yuya Mizukami, Kosuke Kusamori, Yuka Ogino, Shunsuke Nishimura, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Control of polarization and tumoricidal activity of macrophages by multicellular spheroid formation Control of polarization and tumoricidal activity of macrophages by multicellular spheroid formation Control of polarization and tumoricidal activity of macrophages by multicellular spheroid formation Journal of Controlled Release, 270, 177-183 Journal of Controlled Release, 270, 177-183 Journal of Controlled Release, 270, 177-183 2018/01/28 Refereed English Research paper(scientific journal) Disclose to all
Yuki Araie, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuki Araie, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuki Araie, Yosuke Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Enhanced activity of immunosuppressive oligodeoxynucleotides by incorporating them into hexapod-like nanostructured DNA Enhanced activity of immunosuppressive oligodeoxynucleotides by incorporating them into hexapod-like nanostructured DNA Enhanced activity of immunosuppressive oligodeoxynucleotides by incorporating them into hexapod-like nanostructured DNA Biological and Pharmaceutical Bulletin, 41, 4, 564-569 Biological and Pharmaceutical Bulletin, 41, 4, 564-569 Biological and Pharmaceutical Bulletin, 41, 4, 564-569 2018 Refereed English Research paper(scientific journal) Disclose to all
Takuma Yamashita, Haruka Shinotsuka, Yuki Takahashi, Kana Kato, Makiya Nishikawa, Yoshinobu Takakura Takuma Yamashita, Haruka Shinotsuka, Yuki Takahashi, Kana Kato, Makiya Nishikawa, Yoshinobu Takakura Takuma Yamashita, Haruka Shinotsuka, Yuki Takahashi, Kana Kato, Makiya Nishikawa, Yoshinobu Takakura Screening of Exosome-Tropic RNA Screening of Exosome-Tropic RNA Screening of Exosome-Tropic RNA BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 12, 2140-2145 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 12, 2140-2145 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 12, 2140-2145 2017/12 Refereed English Research paper(scientific journal) Disclose to all
Kohta Mohri, Kengo Nagata, Shozo Ohtsuki, Shiori Toyama, Mao Nonomura, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa, Shinji Sakuma Kohta Mohri, Kengo Nagata, Shozo Ohtsuki, Shiori Toyama, Mao Nonomura, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa, Shinji Sakuma Kohta Mohri, Kengo Nagata, Shozo Ohtsuki, Shiori Toyama, Mao Nonomura, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa, Shinji Sakuma Elucidation of the Mechanism of Increased Activity of Immunostimulatory DNA by the Formation of Polypod-like Structure Elucidation of the Mechanism of Increased Activity of Immunostimulatory DNA by the Formation of Polypod-like Structure Elucidation of the Mechanism of Increased Activity of Immunostimulatory DNA by the Formation of Polypod-like Structure PHARMACEUTICAL RESEARCH, 34, 11, 2362-2370 PHARMACEUTICAL RESEARCH, 34, 11, 2362-2370 PHARMACEUTICAL RESEARCH, 34, 11, 2362-2370 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Hirotaka Nakatsuji, Shozo Ohtsuki, Tatsuya Murakami, Hiroshi Imahori, Yuka Umeki, Tomoki Shiomi, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Hirotaka Nakatsuji, Shozo Ohtsuki, Tatsuya Murakami, Hiroshi Imahori, Yuka Umeki, Tomoki Shiomi, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Hirotaka Nakatsuji, Shozo Ohtsuki, Tatsuya Murakami, Hiroshi Imahori, Yuka Umeki, Tomoki Shiomi, Yoshinobu Takakura, Makiya Nishikawa DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy BIOMATERIALS, 146, 136-145 BIOMATERIALS, 146, 136-145 BIOMATERIALS, 146, 136-145 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Reiichi Ariizumi, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Reiichi Ariizumi, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Reiichi Ariizumi, Yoshinobu Takakura Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide MOLECULAR PHARMACEUTICS, 14, 11, 4079-4086 MOLECULAR PHARMACEUTICS, 14, 11, 4079-4086 MOLECULAR PHARMACEUTICS, 14, 11, 4079-4086 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Atsushi Hamana, Yuki Takahashi, Takuro Uchida, Makiya Nishikawa, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Takuro Uchida, Makiya Nishikawa, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Takuro Uchida, Makiya Nishikawa, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus ANTIVIRAL RESEARCH, 146, 130-138 ANTIVIRAL RESEARCH, 146, 130-138 ANTIVIRAL RESEARCH, 146, 130-138 2017/10 Refereed English Research paper(scientific journal) Disclose to all
Shozo Ohtsuki, Yuki Takahashi, Takao Inoue, Yoshinobu Takakura, Makiya Nishikawa Shozo Ohtsuki, Yuki Takahashi, Takao Inoue, Yoshinobu Takakura, Makiya Nishikawa Shozo Ohtsuki, Yuki Takahashi, Takao Inoue, Yoshinobu Takakura, Makiya Nishikawa Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene SCIENTIFIC REPORTS, 7, 1, 13661 SCIENTIFIC REPORTS, 7, 1, 13661 SCIENTIFIC REPORTS, 7, 1, 13661 2017/10 Refereed English Research paper(scientific journal) Disclose to all
Yuka Umeki, Masaaki Saito, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuka Umeki, Masaaki Saito, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuka Umeki, Masaaki Saito, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Retardation of Antigen Release from DNA Hydrogel Using Cholesterol-Modified DNA for Increased Antigen-Specific Immune Response Retardation of Antigen Release from DNA Hydrogel Using Cholesterol-Modified DNA for Increased Antigen-Specific Immune Response Retardation of Antigen Release from DNA Hydrogel Using Cholesterol-Modified DNA for Increased Antigen-Specific Immune Response ADVANCED HEALTHCARE MATERIALS, 6, 20 ADVANCED HEALTHCARE MATERIALS, 6, 20 ADVANCED HEALTHCARE MATERIALS, 6, 20 2017/10 Refereed English Research paper(scientific journal) Disclose to all
Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells CANCER SCIENCE, 108, 9, 1803-1810 CANCER SCIENCE, 108, 9, 1803-1810 CANCER SCIENCE, 108, 9, 1803-1810 2017/09 Refereed English Research paper(scientific journal) Disclose to all
Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 9, 2265-2269 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 9, 2265-2269 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 9, 2265-2269 2017/09 Refereed English Disclose to all
Yosuke Takahashi, Tatsuoki Maezawa, Yuki Araie, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Takahashi Y, Maezawa T, Araie Y, Takahashi Y, Takakura Y, Nishikawa M Yosuke Takahashi, Tatsuoki Maezawa, Yuki Araie, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa In Vitro and In Vivo Stimulation of Toll-Like Receptor 9 by CpG Oligodeoxynucleotides Incorporated Into Polypod-Like DNA Nanostructures In Vitro and In Vivo Stimulation of Toll-Like Receptor 9 by CpG Oligodeoxynucleotides Incorporated Into Polypod-Like DNA Nanostructures. In Vitro and In Vivo Stimulation of Toll-Like Receptor 9 by CpG Oligodeoxynucleotides Incorporated Into Polypod-Like DNA Nanostructures JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 9, 2457-2462 Journal of pharmaceutical sciences, 106, 9, 2457-2462 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 9, 2457-2462 2017/09 Refereed English Research paper(scientific journal) Disclose to all
Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells. Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells. Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells. Cancer science, 108, 9, 1803-1810 Cancer science, 108, 9, 1803-1810 Cancer science, 108, 9, 1803-1810 2017/09 Refereed English Disclose to all
Tomoko Nishikawa, Yutaro Tanaka, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Yuka Ogino, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tomoko Nishikawa, Yutaro Tanaka, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Yuka Ogino, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tomoko Nishikawa, Yutaro Tanaka, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Yuka Ogino, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Using size-controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice Using size-controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice Using size-controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice BIOTECHNOLOGY JOURNAL, 12, 8 BIOTECHNOLOGY JOURNAL, 12, 8 BIOTECHNOLOGY JOURNAL, 12, 8 2017/08 Refereed English Research paper(scientific journal) Disclose to all
Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Atsushi Hamana, Yuki Takahashi, Akane Tanioka, Makiya Nishikawa, Yoshinobu Takakura Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector MOLECULAR PHARMACEUTICS, 14, 4, 1212-1217 MOLECULAR PHARMACEUTICS, 14, 4, 1212-1217 MOLECULAR PHARMACEUTICS, 14, 4, 1212-1217 2017/04 Refereed English Research paper(scientific journal) Disclose to all
Mitsuru Ando, Mai Fujimoto, Yuki Takahashi, Makiya Nishikawa, Atsushi Hamana, Yoshinobu Takakura Mitsuru Ando, Mai Fujimoto, Yuki Takahashi, Makiya Nishikawa, Atsushi Hamana, Yoshinobu Takakura Mitsuru Ando, Mai Fujimoto, Yuki Takahashi, Makiya Nishikawa, Atsushi Hamana, Yoshinobu Takakura Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 3, 892-897 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 3, 892-897 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 3, 892-897 2017/03 Refereed English Research paper(scientific journal) Disclose to all
Tomoko Nishikawa, Yutaro Tanaka, Makiya Nishikawa, Yuka Ogino, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Tomoko Nishikawa, Yutaro Tanaka, Makiya Nishikawa, Yuka Ogino, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Tomoko Nishikawa, Yutaro Tanaka, Makiya Nishikawa, Yuka Ogino, Kosuke Kusamori, Narumi Mizuno, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 3, 334-338 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 3, 334-338 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 40, 3, 334-338 2017/03 Refereed English Research paper(scientific journal) Disclose to all
Takahashi Y, Nishikawa M, Takakura Y Takahashi Y, Nishikawa M, Takakura Y Takahashi Y, Nishikawa M, Takakura Y In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase. In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase. In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase. Methods in molecular biology (Clifton, N.J.), 1660, 245-254 Methods in molecular biology (Clifton, N.J.), 1660, 245-254 Methods in molecular biology (Clifton, N.J.), 1660, 245-254 2017 Refereed English Disclose to all
Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Akihiro Matsumoto, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Masaki Morishita, Chonlada Charoenviriyakul, Hideo Saji, Yoshinobu Takakura Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 1, 168-175 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 1, 168-175 JOURNAL OF PHARMACEUTICAL SCIENCES, 106, 1, 168-175 2017/01 Refereed English Research paper(scientific journal) Disclose to all
Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Chonlada Charoenviriyakul, Yuki Takahashi, Masaki Morishita, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 316-322 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 316-322 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 316-322 2017/01 Refereed English Research paper(scientific journal) Disclose to all
Yumiko Ishii-Mizuno, Yuka Umeki, Yoshinori Onuki, Hiroshi Watanabe, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yumiko Ishii-Mizuno, Yuka Umeki, Yoshinori Onuki, Hiroshi Watanabe, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yumiko Ishii-Mizuno, Yuka Umeki, Yoshinori Onuki, Hiroshi Watanabe, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Improved sustained release of antigen from immunostimulatory DNA hydrogel by electrostatic interaction with chitosan Improved sustained release of antigen from immunostimulatory DNA hydrogel by electrostatic interaction with chitosan Improved sustained release of antigen from immunostimulatory DNA hydrogel by electrostatic interaction with chitosan INTERNATIONAL JOURNAL OF PHARMACEUTICS, 516, 1-2, 392-400 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 516, 1-2, 392-400 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 516, 1-2, 392-400 2017/01 Refereed English Research paper(scientific journal) Disclose to all
Masaki Morishita, Yuki Takahashi, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Akihiro Matsumoto, Makiya Nishikawa, Yoshinobu Takakura Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA BIOMATERIALS, 111, 55-65 BIOMATERIALS, 111, 55-65 BIOMATERIALS, 111, 55-65 2016/12 Refereed English Research paper(scientific journal) Disclose to all
Atsushi Hamana, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Hamana A, Takahashi Y, Nishikawa M, Takakura Y Atsushi Hamana, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-beta for Cancer Gene Therapy Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-β for Cancer Gene Therapy. Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-beta for Cancer Gene Therapy HUMAN GENE THERAPY, 27, 11, 936-945 Human gene therapy, 27, 11, 936-945 HUMAN GENE THERAPY, 27, 11, 936-945 2016/11 Refereed English Research paper(scientific journal) Disclose to all
Y. Yin, Y. Takahashi, A. Hamana, M. Nishikawa, Y. Takakura Y. Yin, Y. Takahashi, A. Hamana, M. Nishikawa, Y. Takakura Y. Yin, Y. Takahashi, A. Hamana, M. Nishikawa, Y. Takakura Effects of transgene expression level per cell in mice livers on induction of transgene-specific immune responses after hydrodynamic gene transfer Effects of transgene expression level per cell in mice livers on induction of transgene-specific immune responses after hydrodynamic gene transfer Effects of transgene expression level per cell in mice livers on induction of transgene-specific immune responses after hydrodynamic gene transfer GENE THERAPY, 23, 7, 565-571 GENE THERAPY, 23, 7, 565-571 GENE THERAPY, 23, 7, 565-571 2016/07 Refereed English Research paper(scientific journal) Disclose to all
Yuki Murakami, Takaaki Ishibashi, Eiichi Tomita, Yukio Imamura, Tomoyuki Tashiro, Kanitta Watcharanurak, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura, Satoko Mitani, Hidetsugu Fujigaki, Yoshiji Ohta, Hisako Kubo, Takayoshi Mamiya, Toshitaka Nabeshima, Hyoung-Chun Kim, Yasuko Yamamoto, Kuniaki Saito Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K Yuki Murakami, Takaaki Ishibashi, Eiichi Tomita, Yukio Imamura, Tomoyuki Tashiro, Kanitta Watcharanurak, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura, Satoko Mitani, Hidetsugu Fujigaki, Yoshiji Ohta, Hisako Kubo, Takayoshi Mamiya, Toshitaka Nabeshima, Hyoung-Chun Kim, Yasuko Yamamoto, Kuniaki Saito Depressive symptoms as a side effect of Interferon-alpha therapy induced by induction of indoleamine 2,3-dioxygenase 1 Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1. Depressive symptoms as a side effect of Interferon-alpha therapy induced by induction of indoleamine 2,3-dioxygenase 1 SCIENTIFIC REPORTS, 6, 29920 Scientific reports, 6, 29920 SCIENTIFIC REPORTS, 6, 29920 2016/07 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Sanada, Tomoki Shiomi, Tadashi Okobira, Mengmeng Tan, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Tomoki Shiomi, Tadashi Okobira, Mengmeng Tan, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Tomoki Shiomi, Tadashi Okobira, Mengmeng Tan, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai Polypod-Shaped DNAs: Small-Angle X-ray Scattering and Immunostimulatory Activity Polypod-Shaped DNAs: Small-Angle X-ray Scattering and Immunostimulatory Activity Polypod-Shaped DNAs: Small-Angle X-ray Scattering and Immunostimulatory Activity LANGMUIR, 32, 15, 3760-3765 LANGMUIR, 32, 15, 3760-3765 LANGMUIR, 32, 15, 3760-3765 2016/04 Refereed English Research paper(scientific journal) Disclose to all
Shoichi Takagi, Yuki Takahashi, Kanako Sugimura, Makiya Nishikawa, Yoshinobu Takakura Shoichi Takagi, Yuki Takahashi, Kanako Sugimura, Makiya Nishikawa, Yoshinobu Takakura Shoichi Takagi, Yuki Takahashi, Kanako Sugimura, Makiya Nishikawa, Yoshinobu Takakura Application of Magnesium Pyrophosphate-Based Sponge-Like Microparticles to Enhance the Delivery Efficiency and Adjuvant Effects of Polyriboinosinic-Polyribocytidylic Acid in Immune Cells Application of Magnesium Pyrophosphate-Based Sponge-Like Microparticles to Enhance the Delivery Efficiency and Adjuvant Effects of Polyriboinosinic-Polyribocytidylic Acid in Immune Cells Application of Magnesium Pyrophosphate-Based Sponge-Like Microparticles to Enhance the Delivery Efficiency and Adjuvant Effects of Polyriboinosinic-Polyribocytidylic Acid in Immune Cells JOURNAL OF PHARMACEUTICAL SCIENCES, 105, 2, 766-772 JOURNAL OF PHARMACEUTICAL SCIENCES, 105, 2, 766-772 JOURNAL OF PHARMACEUTICAL SCIENCES, 105, 2, 766-772 2016/02 Refereed English Research paper(scientific journal) Disclose to all
Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (vol 5, 14979, 2015) Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (vol 5, 14979, 2015) Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (vol 5, 14979, 2015) SCIENTIFIC REPORTS, 6, 17249 SCIENTIFIC REPORTS, 6, 17249 SCIENTIFIC REPORTS, 6, 17249 2016/01 Refereed English Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Analysis and Control of in Vivo Kinetics of Exosomes for the Development of Exosome-based DDS Analysis and Control of in Vivo Kinetics of Exosomes for the Development of Exosome-based DDS Analysis and Control of in Vivo Kinetics of Exosomes for the Development of Exosome-based DDS YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 136, 1, 49-53 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 136, 1, 49-53 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 136, 1, 49-53 2016/01 Refereed Japanese Disclose to all
Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids PHARMACEUTICAL RESEARCH, 33, 1, 247-256 PHARMACEUTICAL RESEARCH, 33, 1, 247-256 PHARMACEUTICAL RESEARCH, 33, 1, 247-256 2016/01 Refereed English Research paper(scientific journal) Disclose to all
Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 2016/01 Refereed English Research paper(scientific journal) Disclose to all
Takuma Yamashita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Takuma Yamashita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Takuma Yamashita, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 98, 1-8 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 98, 1-8 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 98, 1-8 2016/01 Refereed English Research paper(scientific journal) Disclose to all
Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yu Nishida, Shozo Ohtsuki, Yuki Araie, Yuka Umeki, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12, 1, 123-130 2016/01 Refereed English Research paper(scientific journal) Disclose to all
Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Yutaro Tanaka, Yuya Mizukami, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids PHARMACEUTICAL RESEARCH, 33, 1, 247-256 PHARMACEUTICAL RESEARCH, 33, 1, 247-256 PHARMACEUTICAL RESEARCH, 33, 1, 247-256 2016/01 Refereed English Research paper(scientific journal) Disclose to all
Tomoki Shiomi, Mengmeng Tan, Natsuki Takahashi, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tomoki Shiomi, Mengmeng Tan, Natsuki Takahashi, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Tomoki Shiomi, Mengmeng Tan, Natsuki Takahashi, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA NANO RESEARCH, 8, 12, 3764-3771 NANO RESEARCH, 8, 12, 3764-3771 NANO RESEARCH, 8, 12, 3764-3771 2015/12 Refereed English Research paper(scientific journal) Disclose to all
Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Tomoya Yata, Yuki Takahashi, Mengmeng Tan, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yoshinobu Takakura, Makiya Nishikawa Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion SCIENTIFIC REPORTS, 5 SCIENTIFIC REPORTS, 5 SCIENTIFIC REPORTS, 5 2015/10 Refereed English Research paper(scientific journal) Disclose to all
Shozo Ohtsuki, Noriyuki Matsuzaki, Kohta Mohri, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Kenichi Ishiyama, Norimitsu Kadowaki, Yoshinobu Takakura, Makiya Nishikawa Shozo Ohtsuki, Noriyuki Matsuzaki, Kohta Mohri, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Kenichi Ishiyama, Norimitsu Kadowaki, Yoshinobu Takakura, Makiya Nishikawa Shozo Ohtsuki, Noriyuki Matsuzaki, Kohta Mohri, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Kenichi Ishiyama, Norimitsu Kadowaki, Yoshinobu Takakura, Makiya Nishikawa Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells NUCLEIC ACID THERAPEUTICS, 25, 5, 245-253 NUCLEIC ACID THERAPEUTICS, 25, 5, 245-253 NUCLEIC ACID THERAPEUTICS, 25, 5, 245-253 2015/10 Refereed English Research paper(scientific journal) Disclose to all
Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity ADVANCED FUNCTIONAL MATERIALS, 25, 36, 5758-5767 ADVANCED FUNCTIONAL MATERIALS, 25, 36, 5758-5767 ADVANCED FUNCTIONAL MATERIALS, 25, 36, 5758-5767 2015/09 Refereed English Research paper(scientific journal) Disclose to all
Lei Zang, Makiya Nishikawa, Mitsuru Ando, Yuki Takahashi, Yoshinobu Takakura Lei Zang, Makiya Nishikawa, Mitsuru Ando, Yuki Takahashi, Yoshinobu Takakura Lei Zang, Makiya Nishikawa, Mitsuru Ando, Yuki Takahashi, Yoshinobu Takakura Contribution of epigenetic modifications to the decline in transgene expression from plasmid DNA in mouse liver Contribution of epigenetic modifications to the decline in transgene expression from plasmid DNA in mouse liver Contribution of epigenetic modifications to the decline in transgene expression from plasmid DNA in mouse liver Pharmaceutics, 7, 3, 199-212 Pharmaceutics, 7, 3, 199-212 Pharmaceutics, 7, 3, 199-212 2015/08/09 Refereed English Research paper(scientific journal) Disclose to all
Kohta Mohri, Eri Kusuki, Shozo Ohtsuki, Natsuki Takahashi, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Kohta Mohri, Eri Kusuki, Shozo Ohtsuki, Natsuki Takahashi, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Kohta Mohri, Eri Kusuki, Shozo Ohtsuki, Natsuki Takahashi, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa Self-Assembling DNA Dendrimer for Effective Delivery of Immunostimulatory CpG DNA to Immune Cells Self-Assembling DNA Dendrimer for Effective Delivery of Immunostimulatory CpG DNA to Immune Cells Self-Assembling DNA Dendrimer for Effective Delivery of Immunostimulatory CpG DNA to Immune Cells BIOMACROMOLECULES, 16, 4, 1095-1101 BIOMACROMOLECULES, 16, 4, 1095-1101 BIOMACROMOLECULES, 16, 4, 1095-1101 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Yumiko Ishii-Mizuno, Yuka Umeki, Yuki Takahashi, Yukinori Kato, Tetsuji Takabayashi, Shigeharu Fujieda, Yoshinobu Takakura, Makiya Nishikawa Yumiko Ishii-Mizuno, Yuka Umeki, Yuki Takahashi, Yukinori Kato, Tetsuji Takabayashi, Shigeharu Fujieda, Yoshinobu Takakura, Makiya Nishikawa Yumiko Ishii-Mizuno, Yuka Umeki, Yuki Takahashi, Yukinori Kato, Tetsuji Takabayashi, Shigeharu Fujieda, Yoshinobu Takakura, Makiya Nishikawa Nasal delivery of Japanese cedar pollen Cryj1 by using self-gelling immunostimulatory DNA for effective induction of immune responses in mice Nasal delivery of Japanese cedar pollen Cryj1 by using self-gelling immunostimulatory DNA for effective induction of immune responses in mice Nasal delivery of Japanese cedar pollen Cryj1 by using self-gelling immunostimulatory DNA for effective induction of immune responses in mice JOURNAL OF CONTROLLED RELEASE, 200, 52-59 JOURNAL OF CONTROLLED RELEASE, 200, 52-59 JOURNAL OF CONTROLLED RELEASE, 200, 52-59 2015/02 Refereed English Research paper(scientific journal) Disclose to all
Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Kana Kato, Takuma Yamashita, Takafumi Imai, Hideo Saji, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Kana Kato, Takuma Yamashita, Takafumi Imai, Hideo Saji, Yoshinobu Takakura Masaki Morishita, Yuki Takahashi, Makiya Nishikawa, Kohei Sano, Kana Kato, Takuma Yamashita, Takafumi Imai, Hideo Saji, Yoshinobu Takakura Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice JOURNAL OF PHARMACEUTICAL SCIENCES, 104, 2, 705-713 JOURNAL OF PHARMACEUTICAL SCIENCES, 104, 2, 705-713 JOURNAL OF PHARMACEUTICAL SCIENCES, 104, 2, 705-713 2015/02 Refereed English Research paper(scientific journal) Disclose to all
Takafumi Imai, Yuki Takahashi, Makiya Nishikawa, Kana Kato, Masaki Morishita, Takuma Yamashita, Akihiro Matsumoto, Chonlada Charoenviriyakul, Yoshinobu Takakura Takafumi Imai, Yuki Takahashi, Makiya Nishikawa, Kana Kato, Masaki Morishita, Takuma Yamashita, Akihiro Matsumoto, Chonlada Charoenviriyakul, Yoshinobu Takakura Takafumi Imai, Yuki Takahashi, Makiya Nishikawa, Kana Kato, Masaki Morishita, Takuma Yamashita, Akihiro Matsumoto, Chonlada Charoenviriyakul, Yoshinobu Takakura Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice. Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice. Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice. Journal of extracellular vesicles, 4, 26238-26238 Journal of extracellular vesicles, 4, 26238-26238 Journal of extracellular vesicles, 4, 26238-26238 2015 Refereed English Disclose to all
Heidie L. Frisco-Cabanos, Mizuki Watanabe, Naoki Okumura, Kosuke Kusamori, Naohiro Takemoto, Junichiro Takaya, Shin-ichi Sato, Sayumi Yamazoe, Yoshinobu Takakura, Shigeru Kinoshita, Makiya Nishikawa, Noriko Koizumi, Motonari Uesugi Heidie L. Frisco-Cabanos, Mizuki Watanabe, Naoki Okumura, Kosuke Kusamori, Naohiro Takemoto, Junichiro Takaya, Shin-ichi Sato, Sayumi Yamazoe, Yoshinobu Takakura, Shigeru Kinoshita, Makiya Nishikawa, Noriko Koizumi, Motonari Uesugi Heidie L. Frisco-Cabanos, Mizuki Watanabe, Naoki Okumura, Kosuke Kusamori, Naohiro Takemoto, Junichiro Takaya, Shin-ichi Sato, Sayumi Yamazoe, Yoshinobu Takakura, Shigeru Kinoshita, Makiya Nishikawa, Noriko Koizumi, Motonari Uesugi Synthetic Molecules that Protect Cells from Anoikis and Their Use in Cell Transplantation Synthetic Molecules that Protect Cells from Anoikis and Their Use in Cell Transplantation Synthetic Molecules that Protect Cells from Anoikis and Their Use in Cell Transplantation ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 42, 11208-11213 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 42, 11208-11213 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 42, 11208-11213 2014/10 Refereed English Research paper(scientific journal) Disclose to all
K. W Watcharanurak, L. Zang, M. Nishikawa, K. Yoshinaga, Y. Yamamoto, Y. Takahashi, M. Ando, K. Saito, Y. Watanabe, Y. Takakura Watcharanurak K, Zang L, Nishikawa M, Yoshinaga K, Yamamoto Y, Takahashi Y, Ando M, Saito K, Watanabe Y, Takakura Y K. W Watcharanurak, L. Zang, M. Nishikawa, K. Yoshinaga, Y. Yamamoto, Y. Takahashi, M. Ando, K. Saito, Y. Watanabe, Y. Takakura Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon gamma gene transfer on interferon gamma-mediated antitumor activity Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer on interferon γ-mediated antitumor activity. Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon gamma gene transfer on interferon gamma-mediated antitumor activity GENE THERAPY, 21, 9, 794-801 Gene therapy, 21, 9, 794-801 GENE THERAPY, 21, 9, 794-801 2014/09 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Sanada, Shunsuke Sakamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Noboru Ohta, Naoto Yagi, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Shunsuke Sakamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Noboru Ohta, Naoto Yagi, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Shunsuke Sakamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Noboru Ohta, Naoto Yagi, Makiya Nishikawa, Isamu Akiba, Yoshinobu Takakura, Kazuo Sakurai X-ray Scattering from Immunostimulatory Tetrapod-Shaped DNA in Aqueous Solution To Explore Its Biological Activity-Conformation Relationship X-ray Scattering from Immunostimulatory Tetrapod-Shaped DNA in Aqueous Solution To Explore Its Biological Activity-Conformation Relationship X-ray Scattering from Immunostimulatory Tetrapod-Shaped DNA in Aqueous Solution To Explore Its Biological Activity-Conformation Relationship JOURNAL OF PHYSICAL CHEMISTRY B, 118, 35, 10373-10379 JOURNAL OF PHYSICAL CHEMISTRY B, 118, 35, 10373-10379 JOURNAL OF PHYSICAL CHEMISTRY B, 118, 35, 10373-10379 2014/09 Refereed English Research paper(scientific journal) Disclose to all
Kohta Mohri, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura DNA nanotechnology-based development of delivery systems for bioactive compounds DNA nanotechnology-based development of delivery systems for bioactive compounds DNA nanotechnology-based development of delivery systems for bioactive compounds EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 58, 26-33 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 58, 26-33 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 58, 26-33 2014/07 Refereed English Disclose to all
Tsuyoshi Kiyota, Yuki Takahashi, Kanitta Watcharanurak, Makiya Nishikawa, Saori Ohara, Mitsuru Ando, Yoshihiko Watanabe, Yoshinobu Takakura Kiyota T, Takahashi Y, Watcharanurak K, Nishikawa M, Ohara S, Ando M, Watanabe Y, Takakura Y Tsuyoshi Kiyota, Yuki Takahashi, Kanitta Watcharanurak, Makiya Nishikawa, Saori Ohara, Mitsuru Ando, Yoshihiko Watanabe, Yoshinobu Takakura Enhancement of Anticancer Effect of Interferon-gamma Gene Transfer against Interferon-gamma-Resistant Tumor by Depletion of Tumor-Associated Macrophages Enhancement of anticancer effect of interferon-γ gene transfer against interferon-γ-resistant tumor by depletion of tumor-associated macrophages. Enhancement of Anticancer Effect of Interferon-gamma Gene Transfer against Interferon-gamma-Resistant Tumor by Depletion of Tumor-Associated Macrophages MOLECULAR PHARMACEUTICS, 11, 5, 1542-1549 Molecular pharmaceutics, 11, 5, 1542-1549 MOLECULAR PHARMACEUTICS, 11, 5, 1542-1549 2014/05 Refereed English Research paper(scientific journal) Disclose to all
Shota Uno, Makiya Nishikawa, Kohta Mohri, Yuka Umeki, Noriyuki Matsuzaki, Yuki Takahashi, Haruyuki Fujita, Norimitsu Kadowaki, Yoshinobu Takakura Shota Uno, Makiya Nishikawa, Kohta Mohri, Yuka Umeki, Noriyuki Matsuzaki, Yuki Takahashi, Haruyuki Fujita, Norimitsu Kadowaki, Yoshinobu Takakura Shota Uno, Makiya Nishikawa, Kohta Mohri, Yuka Umeki, Noriyuki Matsuzaki, Yuki Takahashi, Haruyuki Fujita, Norimitsu Kadowaki, Yoshinobu Takakura Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 10, 4, 765-774 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 10, 4, 765-774 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 10, 4, 765-774 2014/05 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Kohei Ogawa, Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Natsuki Takahashi, Eri Kusuki, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Kohei Ogawa, Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Natsuki Takahashi, Eri Kusuki, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Kohei Ogawa, Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Natsuki Takahashi, Eri Kusuki, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery JOURNAL OF CONTROLLED RELEASE, 180, 1, 25-32 JOURNAL OF CONTROLLED RELEASE, 180, 1, 25-32 JOURNAL OF CONTROLLED RELEASE, 180, 1, 25-32 2014/04 Refereed English Research paper(scientific journal) Disclose to all
Yalei Yin, Yuki Takahashi, Norifumi Ebisuura, Makiya Nishikawa, Yoshinobu Takakura Yalei Yin, Yuki Takahashi, Norifumi Ebisuura, Makiya Nishikawa, Yoshinobu Takakura Yalei Yin, Yuki Takahashi, Norifumi Ebisuura, Makiya Nishikawa, Yoshinobu Takakura Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression JOURNAL OF GENE MEDICINE, 16, 3-4, 97-106 JOURNAL OF GENE MEDICINE, 16, 3-4, 97-106 JOURNAL OF GENE MEDICINE, 16, 3-4, 97-106 2014/03 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Mitsuru Ando, Makiya Nishikawa, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Takahashi Y, Ando M, Nishikawa M, Hiraga N, Imamura M, Chayama K, Takakura Y Yuki Takahashi, Mitsuru Ando, Makiya Nishikawa, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer Long-term elimination of hepatitis C virus from human hepatocyte chimeric mice after interferon-γ gene transfer. Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer HUMAN GENE THERAPY CLINICAL DEVELOPMENT, 25, 1, 28-39 Human gene therapy. Clinical development, 25, 1, 28-39 HUMAN GENE THERAPY CLINICAL DEVELOPMENT, 25, 1, 28-39 2014/03 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura The perspective of DDS from the viewpoint of a basic researcher The perspective of DDS from the viewpoint of a basic researcher The perspective of DDS from the viewpoint of a basic researcher Drug Delivery System, 29, 1, 30-38 Drug Delivery System, 29, 1, 30-38 Drug Delivery System, 29, 1, 30-38 2014 Refereed Japanese Research paper(scientific journal) Disclose to all
Mitsuru Ando, Yuki Takahashi, Takuma Yamashita, Mai Fujimoto, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Ando M, Takahashi Y, Yamashita T, Fujimoto M, Nishikawa M, Watanabe Y, Takakura Y Mitsuru Ando, Yuki Takahashi, Takuma Yamashita, Mai Fujimoto, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Prevention of adverse events of interferon gamma gene therapy by gene delivery of interferon gamma-heparin-binding domain fusion protein in mice Prevention of adverse events of interferon γ gene therapy by gene delivery of interferon γ-heparin-binding domain fusion protein in mice. Prevention of adverse events of interferon gamma gene therapy by gene delivery of interferon gamma-heparin-binding domain fusion protein in mice MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 1, 14023 Molecular therapy. Methods & clinical development, 1, 14023 MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 1, 14023 2014 Refereed English Research paper(scientific journal) Disclose to all
Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice JOURNAL OF CONTROLLED RELEASE, 173, 1, 119-124 JOURNAL OF CONTROLLED RELEASE, 173, 1, 119-124 JOURNAL OF CONTROLLED RELEASE, 173, 1, 119-124 2014/01 Refereed English Research paper(scientific journal) Disclose to all
Hanae Mukumoto, Yuki Takahashi, Mitsuru Ando, Makiya Nishikawa, Yoshinobu Takakura Hanae Mukumoto, Yuki Takahashi, Mitsuru Ando, Makiya Nishikawa, Yoshinobu Takakura Hanae Mukumoto, Yuki Takahashi, Mitsuru Ando, Makiya Nishikawa, Yoshinobu Takakura Expression Profile-Dependent Improvement of Insulin Sensitivity by Gene Delivery of Interleukin-6 in a Mouse Model of Type II Diabetes Expression Profile-Dependent Improvement of Insulin Sensitivity by Gene Delivery of Interleukin-6 in a Mouse Model of Type II Diabetes Expression Profile-Dependent Improvement of Insulin Sensitivity by Gene Delivery of Interleukin-6 in a Mouse Model of Type II Diabetes MOLECULAR PHARMACEUTICS, 10, 10, 3812-3821 MOLECULAR PHARMACEUTICS, 10, 10, 3812-3821 MOLECULAR PHARMACEUTICS, 10, 10, 3812-3821 2013/10 Refereed English Research paper(scientific journal) Disclose to all
Noriko Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura Noriko Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura Noriko Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura Gene Delivery of Albumin Binding Peptide-Interferon-gamma Fusion Protein with Improved Pharmacokinetic Properties and Sustained Biological Activity Gene Delivery of Albumin Binding Peptide-Interferon-gamma Fusion Protein with Improved Pharmacokinetic Properties and Sustained Biological Activity Gene Delivery of Albumin Binding Peptide-Interferon-gamma Fusion Protein with Improved Pharmacokinetic Properties and Sustained Biological Activity JOURNAL OF PHARMACEUTICAL SCIENCES, 102, 9, 3110-3118 JOURNAL OF PHARMACEUTICAL SCIENCES, 102, 9, 3110-3118 JOURNAL OF PHARMACEUTICAL SCIENCES, 102, 9, 3110-3118 2013/09 Refereed English Research paper(scientific journal) Disclose to all
Naohiro Takemoto, Tetsuya Suehara, Heidie L. Frisco, Shin-ichi Sato, Takuhito Sezaki, Kosuke Kusamori, Yoshinori Kawazoe, Sun Min Park, Sayumi Yamazoe, Yoshiyuki Mizuhata, Rintaro Inoue, Gavin J. Miller, Steen U. Hansen, Gordon C. Jayson, John M. Gardiner, Toshiji Kanaya, Norihiro Tokitoh, Kazumitsu Ueda, Yoshinobu Takakura, Noriyuki Kioka, Makiya Nishikawa, Motonari Uesugi Naohiro Takemoto, Tetsuya Suehara, Heidie L. Frisco, Shin-ichi Sato, Takuhito Sezaki, Kosuke Kusamori, Yoshinori Kawazoe, Sun Min Park, Sayumi Yamazoe, Yoshiyuki Mizuhata, Rintaro Inoue, Gavin J. Miller, Steen U. Hansen, Gordon C. Jayson, John M. Gardiner, Toshiji Kanaya, Norihiro Tokitoh, Kazumitsu Ueda, Yoshinobu Takakura, Noriyuki Kioka, Makiya Nishikawa, Motonari Uesugi Naohiro Takemoto, Tetsuya Suehara, Heidie L. Frisco, Shin-ichi Sato, Takuhito Sezaki, Kosuke Kusamori, Yoshinori Kawazoe, Sun Min Park, Sayumi Yamazoe, Yoshiyuki Mizuhata, Rintaro Inoue, Gavin J. Miller, Steen U. Hansen, Gordon C. Jayson, John M. Gardiner, Toshiji Kanaya, Norihiro Tokitoh, Kazumitsu Ueda, Yoshinobu Takakura, Noriyuki Kioka, Makiya Nishikawa, Motonari Uesugi Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion Small-Molecule-Induced Clustering of Heparan Sulfate Promotes Cell Adhesion JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135, 30, 11032-11039 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135, 30, 11032-11039 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 135, 30, 11032-11039 2013/07 Refereed English Research paper(scientific journal) Disclose to all
Kazunori Shimizu, Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Shingo Katano, Yuki Takahashi, Yoshinobu Takakura, Satoshi Konishi Kazunori Shimizu, Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Shingo Katano, Yuki Takahashi, Yoshinobu Takakura, Satoshi Konishi Kazunori Shimizu, Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Akira Masuzawa, Shingo Katano, Yuki Takahashi, Yoshinobu Takakura, Satoshi Konishi Poly(N-isopropylacrylamide)-coated microwell arrays for construction and recovery of multicellular spheroids Poly(N-isopropylacrylamide)-coated microwell arrays for construction and recovery of multicellular spheroids Poly(N-isopropylacrylamide)-coated microwell arrays for construction and recovery of multicellular spheroids JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 115, 6, 695-699 JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 115, 6, 695-699 JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 115, 6, 695-699 2013/06 Refereed English Research paper(scientific journal) Disclose to all
K. Watcharanurak, M. Nishikawa, Y. Takahashi, K. Kabashima, R. Takahashi, Y. Takakura K. Watcharanurak, M. Nishikawa, Y. Takahashi, K. Kabashima, R. Takahashi, Y. Takakura K. Watcharanurak, M. Nishikawa, Y. Takahashi, K. Kabashima, R. Takahashi, Y. Takakura Regulation of immunological balance by sustained interferon-γ gene transfer for acute phase of atopic dermatitis in mice Regulation of immunological balance by sustained interferon-γ gene transfer for acute phase of atopic dermatitis in mice Regulation of immunological balance by sustained interferon-γ gene transfer for acute phase of atopic dermatitis in mice Gene Therapy, 20, 5, 538-544 Gene Therapy, 20, 5, 538-544 Gene Therapy, 20, 5, 538-544 2013/05 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Haruka Shinotsuka, Yuriko Matsui, Saori Ohara, Takafumi Imai, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Haruka Shinotsuka, Yuriko Matsui, Saori Ohara, Takafumi Imai, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Haruka Shinotsuka, Yuriko Matsui, Saori Ohara, Takafumi Imai, Yoshinobu Takakura Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection JOURNAL OF BIOTECHNOLOGY, 165, 2, 77-84 JOURNAL OF BIOTECHNOLOGY, 165, 2, 77-84 JOURNAL OF BIOTECHNOLOGY, 165, 2, 77-84 2013/05 Refereed English Research paper(scientific journal) Disclose to all
Kosuke Kusamori, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kosuke Kusamori, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Development of multicellular spheroid for cell-based therapy Development of multicellular spheroid for cell-based therapy Development of multicellular spheroid for cell-based therapy Drug Delivery System, 28, 1, 45-53 Drug Delivery System, 28, 1, 45-53 Drug Delivery System, 28, 1, 45-53 2013/04 Refereed English Research paper(scientific journal) Disclose to all
Mitsuru Ando, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura M. Ando, Y. Takahashi, M. Nishikawa, Y. Takakura Mitsuru Ando, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Control of Spatiotemporal Distribution of Interferon gamma by Genetically Fusing Functional Peptides Control of spatiotemporal distribution of interferon γ by genetically fusing functional peptides Control of Spatiotemporal Distribution of Interferon gamma by Genetically Fusing Functional Peptides YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 132, 12, 1399-1406 Yakugaku Zasshi, 132, 12, 1399-1406 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 132, 12, 1399-1406 2012/12 Refereed Japanese Disclose to all
Kanitta Watcharanurak, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kanitta Watcharanurak, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Kanitta Watcharanurak, Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Controlling the kinetics of interferon transgene expression for improved gene therapy Controlling the kinetics of interferon transgene expression for improved gene therapy Controlling the kinetics of interferon transgene expression for improved gene therapy JOURNAL OF DRUG TARGETING, 20, 9, 764-769 JOURNAL OF DRUG TARGETING, 20, 9, 764-769 JOURNAL OF DRUG TARGETING, 20, 9, 764-769 2012/11 Refereed English Disclose to all
Kohta Mohri, Natsuki Takahashi, Makiya Nishikawa, Eri Kusuki, Tomoki Shiomi, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Natsuki Takahashi, Makiya Nishikawa, Eri Kusuki, Tomoki Shiomi, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Natsuki Takahashi, Makiya Nishikawa, Eri Kusuki, Tomoki Shiomi, Yuki Takahashi, Yoshinobu Takakura Increased immunostimulatory activity of polypod-like structured DNA by ligation of the terminal loop structures Increased immunostimulatory activity of polypod-like structured DNA by ligation of the terminal loop structures Increased immunostimulatory activity of polypod-like structured DNA by ligation of the terminal loop structures JOURNAL OF CONTROLLED RELEASE, 163, 3, 285-292 JOURNAL OF CONTROLLED RELEASE, 163, 3, 285-292 JOURNAL OF CONTROLLED RELEASE, 163, 3, 285-292 2012/11 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Hiroyasu Toyota, Tsuyoshi Kiyota, Yuki Takahashi, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Hiroyasu Toyota, Tsuyoshi Kiyota, Yuki Takahashi, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Hiroyasu Toyota, Tsuyoshi Kiyota, Yuki Takahashi, Yoshinobu Takakura Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA CYTOKINE, 60, 1, 162-170 CYTOKINE, 60, 1, 162-170 CYTOKINE, 60, 1, 162-170 2012/10 Refereed English Research paper(scientific journal) Disclose to all
Sakulrat Rattanakiat, Makiya Nishikawa, Yoshinobu Takakura Sakulrat Rattanakiat, Makiya Nishikawa, Yoshinobu Takakura Sakulrat Rattanakiat, Makiya Nishikawa, Yoshinobu Takakura Self-assembling CpG DNA nanoparticles for efficient antigen delivery and immunostimulation Self-assembling CpG DNA nanoparticles for efficient antigen delivery and immunostimulation Self-assembling CpG DNA nanoparticles for efficient antigen delivery and immunostimulation EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 47, 2, 352-358 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 47, 2, 352-358 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 47, 2, 352-358 2012/09 Refereed English Research paper(scientific journal) Disclose to all
Kohta Mohri, Makiya Nishikawa, Natsuki Takahashi, Tomoki Shiomi, Nao Matsuoka, Kohei Ogawa, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Natsuki Takahashi, Tomoki Shiomi, Nao Matsuoka, Kohei Ogawa, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Natsuki Takahashi, Tomoki Shiomi, Nao Matsuoka, Kohei Ogawa, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura Design and Development of Nanosized DNA Assemblies in Polypod-like Structures as Efficient Vehicles for Immunostimulatory CpG Motifs to Immune Cells Design and Development of Nanosized DNA Assemblies in Polypod-like Structures as Efficient Vehicles for Immunostimulatory CpG Motifs to Immune Cells Design and Development of Nanosized DNA Assemblies in Polypod-like Structures as Efficient Vehicles for Immunostimulatory CpG Motifs to Immune Cells ACS NANO, 6, 7, 5931-5940 ACS NANO, 6, 7, 5931-5940 ACS NANO, 6, 7, 5931-5940 2012/07 Refereed English Research paper(scientific journal) Disclose to all
Daihi Oushiki, Hirotatsu Kojima, Yuki Takahashi, Toru Komatsu, Takuya Terai, Kenjiro Hanaoka, Makiya Nishikawa, Yoshinobu Takakura, Tetsuo Nagano Daihi Oushiki, Hirotatsu Kojima, Yuki Takahashi, Toru Komatsu, Takuya Terai, Kenjiro Hanaoka, Makiya Nishikawa, Yoshinobu Takakura, Tetsuo Nagano Daihi Oushiki, Hirotatsu Kojima, Yuki Takahashi, Toru Komatsu, Takuya Terai, Kenjiro Hanaoka, Makiya Nishikawa, Yoshinobu Takakura, Tetsuo Nagano Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold ANALYTICAL CHEMISTRY, 84, 10, 4404-4410 ANALYTICAL CHEMISTRY, 84, 10, 4404-4410 ANALYTICAL CHEMISTRY, 84, 10, 4404-4410 2012/05 Refereed English Research paper(scientific journal) Disclose to all
Mitsuru Ando, Yuki Takahashi, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura M. Ando, Y. Takahashi, M. Nishikawa, Y. Watanabe, Y. Takakura Mitsuru Ando, Yuki Takahashi, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Constant and steady transgene expression of interferon-gamma by optimization of plasmid construct for safe and effective interferon-gamma gene therapy Constant and steady transgene expression of interferon-γ by optimization of plasmid construct for safe and effective interferon-γ gene therapy Constant and steady transgene expression of interferon-gamma by optimization of plasmid construct for safe and effective interferon-gamma gene therapy JOURNAL OF GENE MEDICINE, 14, 4, 288-295 Journal of Gene Medicine, 14, 4, 288-295 JOURNAL OF GENE MEDICINE, 14, 4, 288-295 2012/04 Refereed English Research paper(scientific journal) Disclose to all
Xin Guan, Makiya Nishikawa, Hisoon Li, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Human Vaccines and Immunotherapeutics, 8, 2, 194-200 Human Vaccines and Immunotherapeutics, 8, 2, 194-200 Human Vaccines and Immunotherapeutics, 8, 2, 194-200 2012/02 Refereed English Research paper(scientific journal) Disclose to all
Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 184-190 HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 184-190 HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 184-190 2012/02 Refereed English Research paper(scientific journal) Disclose to all
Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Hisoon Li, Takahashi Rei, Yuki Takahashi, Yoshinobu Takakura Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 194-200 HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 194-200 HUMAN VACCINES & IMMUNOTHERAPEUTICS, 8, 2, 194-200 2012/02 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Development of safe and effective nonviral gene therapy by eliminating CpG motifs from plasmid DNA vector Development of safe and effective nonviral gene therapy by eliminating CpG motifs from plasmid DNA vector Development of safe and effective nonviral gene therapy by eliminating CpG motifs from plasmid DNA vector Frontiers in Bioscience - Scholar, 4, 1, 133-141 Frontiers in Bioscience - Scholar, 4, 1, 133-141 Frontiers in Bioscience - Scholar, 4, 1, 133-141 2012/01/01 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Naomi Takiguchi, Tetsuya Suehara, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Naomi Takiguchi, Tetsuya Suehara, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Naomi Takiguchi, Tetsuya Suehara, Yoshinobu Takakura Saturation of Transgene Protein Synthesis From mRNA in Cells Producing a Large Number of Transgene mRNA Saturation of Transgene Protein Synthesis From mRNA in Cells Producing a Large Number of Transgene mRNA Saturation of Transgene Protein Synthesis From mRNA in Cells Producing a Large Number of Transgene mRNA BIOTECHNOLOGY AND BIOENGINEERING, 108, 10, 2380-2389 BIOTECHNOLOGY AND BIOENGINEERING, 108, 10, 2380-2389 BIOTECHNOLOGY AND BIOENGINEERING, 108, 10, 2380-2389 2011/10 Refereed English Research paper(scientific journal) Disclose to all
L. Zang, M. Nishikawa, K. Machida, M. Ando, Y. Takahashi, Y. Watanabe, Y. Takakura L. Zang, M. Nishikawa, K. MacHida, M. Ando, Y. Takahashi, Y. Watanabe, Y. Takakura L. Zang, M. Nishikawa, K. Machida, M. Ando, Y. Takahashi, Y. Watanabe, Y. Takakura Inhibition of nuclear delivery of plasmid DNA and transcription by interferon gamma: hurdles to be overcome for sustained gene therapy Inhibition of nuclear delivery of plasmid DNA and transcription by interferon γ: hurdles to be overcome for sustained gene therapy Inhibition of nuclear delivery of plasmid DNA and transcription by interferon gamma: hurdles to be overcome for sustained gene therapy GENE THERAPY, 18, 9, 891-897 Gene Therapy, 18, 9, 891-897 GENE THERAPY, 18, 9, 891-897 2011/09 Refereed English Research paper(scientific journal) Disclose to all
Chika Nishizaki, Makiya Nishikawa, Tomoya Yata, Toshiyuki Yamada, Yuki Takahashi, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Kenji Nakanishi, Yoshinobu Takakura Chika Nishizaki, Makiya Nishikawa, Tomoya Yata, Toshiyuki Yamada, Yuki Takahashi, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Kenji Nakanishi, Yoshinobu Takakura Chika Nishizaki, Makiya Nishikawa, Tomoya Yata, Toshiyuki Yamada, Yuki Takahashi, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Kenji Nakanishi, Yoshinobu Takakura Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice FREE RADICAL BIOLOGY AND MEDICINE, 51, 3, 773-779 FREE RADICAL BIOLOGY AND MEDICINE, 51, 3, 773-779 FREE RADICAL BIOLOGY AND MEDICINE, 51, 3, 773-779 2011/08 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Yoshida, Makiya Nishikawa, Tsuyoshi Kiyota, Hiroyasu Toyota, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Tsuyoshi Kiyota, Hiroyasu Toyota, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Tsuyoshi Kiyota, Hiroyasu Toyota, Yoshinobu Takakura Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice FREE RADICAL BIOLOGY AND MEDICINE, 51, 2, 424-431 FREE RADICAL BIOLOGY AND MEDICINE, 51, 2, 424-431 FREE RADICAL BIOLOGY AND MEDICINE, 51, 2, 424-431 2011/07 Refereed English Research paper(scientific journal) Disclose to all
Noriko Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura N. Miyakawa, M. Nishikawa, Y. Takahashi, M. Ando, M. Misaka, Y. Watanabe, Y. Takakura Noriko Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura Prolonged Circulation Half-life of Interferon gamma Activity by Gene Delivery of Interferon gamma-Serum Albumin Fusion Protein in Mice Prolonged circulation half-life of interferon γ activity by gene delivery of interferon γ-serum albumin fusion protein in mice Prolonged Circulation Half-life of Interferon gamma Activity by Gene Delivery of Interferon gamma-Serum Albumin Fusion Protein in Mice JOURNAL OF PHARMACEUTICAL SCIENCES, 100, 6, 2350-2357 Journal of Pharmaceutical Sciences, 100, 6, 2350-2357 JOURNAL OF PHARMACEUTICAL SCIENCES, 100, 6, 2350-2357 2011/06 Refereed English Research paper(scientific journal) Disclose to all
Naomi Takiguchi, Yuki Takahashi, Makiya Nishikawa, Yuriko Matsui, Yasushi Fukuhara, Daihi Oushiki, Kazuki Kiyose, Kenjiro Hanaoka, Tetsuo Nagano, Yoshinobu Takakura Naomi Takiguchi, Yuki Takahashi, Makiya Nishikawa, Yuriko Matsui, Yasushi Fukuhara, Daihi Oushiki, Kazuki Kiyose, Kenjiro Hanaoka, Tetsuo Nagano, Yoshinobu Takakura Naomi Takiguchi, Yuki Takahashi, Makiya Nishikawa, Yuriko Matsui, Yasushi Fukuhara, Daihi Oushiki, Kazuki Kiyose, Kenjiro Hanaoka, Tetsuo Nagano, Yoshinobu Takakura Positive Correlation Between the Generation of Reactive Oxygen Species and Activation/Reactivation of Transgene Expression After Hydrodynamic Injections into Mice Positive Correlation Between the Generation of Reactive Oxygen Species and Activation/Reactivation of Transgene Expression After Hydrodynamic Injections into Mice Positive Correlation Between the Generation of Reactive Oxygen Species and Activation/Reactivation of Transgene Expression After Hydrodynamic Injections into Mice PHARMACEUTICAL RESEARCH, 28, 4, 702-711 PHARMACEUTICAL RESEARCH, 28, 4, 702-711 PHARMACEUTICAL RESEARCH, 28, 4, 702-711 2011/04 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Nucleic Acid Drug Delivery and Targeting Nucleic Acid Drug Delivery and Targeting Nucleic Acid Drug Delivery and Targeting PHARMACEUTICAL RESEARCH, 28, 4, 691-693 PHARMACEUTICAL RESEARCH, 28, 4, 691-693 PHARMACEUTICAL RESEARCH, 28, 4, 691-693 2011/04 Refereed English Disclose to all
Hiroyuki Yoshida, Makiya Nishikawa, Tsuyoshi Kiyota, Shota Uno, Hiroyasu Toyota, Rei Takahashi, Miwako Narita, Yoshinobu Takakura H. Yoshida, M. Nishikawa, T. Kiyota, S. Uno, H. Toyota, R. Takahashi, M. Narita, Y. Takakura Hiroyuki Yoshida, Makiya Nishikawa, Tsuyoshi Kiyota, Shota Uno, Hiroyasu Toyota, Rei Takahashi, Miwako Narita, Yoshinobu Takakura 5 '-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages 5′-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages 5 '-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages EUROPEAN JOURNAL OF IMMUNOLOGY, 41, 2, 425-436 European Journal of Immunology, 41, 2, 425-436 EUROPEAN JOURNAL OF IMMUNOLOGY, 41, 2, 425-436 2011/02 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Yumiko Mizuno, Kohta Mohri, Nao Matsuoka, Sakulrat Rattanakiat, Yuki Takahashi, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura Makiya Nishikawa, Yumiko Mizuno, Kohta Mohri, Nao Matsuoka, Sakulrat Rattanakiat, Yuki Takahashi, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura Makiya Nishikawa, Yumiko Mizuno, Kohta Mohri, Nao Matsuoka, Sakulrat Rattanakiat, Yuki Takahashi, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice BIOMATERIALS, 32, 2, 488-494 BIOMATERIALS, 32, 2, 488-494 BIOMATERIALS, 32, 2, 488-494 2011/01 Refereed English Research paper(scientific journal) Disclose to all
Nao Matsuoka, Makiya Nishikawa, Kohta Mohri, Sakulrat Rattanakiat, Yoshinobu Takakura Nao Matsuoka, Makiya Nishikawa, Kohta Mohri, Sakulrat Rattanakiat, Yoshinobu Takakura Nao Matsuoka, Makiya Nishikawa, Kohta Mohri, Sakulrat Rattanakiat, Yoshinobu Takakura Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides JOURNAL OF CONTROLLED RELEASE, 148, 3, 311-316 JOURNAL OF CONTROLLED RELEASE, 148, 3, 311-316 JOURNAL OF CONTROLLED RELEASE, 148, 3, 311-316 2010/12 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Optimization of Gene Therapy Effect by Spaciotemporal Control of Expressed Proteins Optimization of Gene Therapy Effect by Spaciotemporal Control of Expressed Proteins Optimization of Gene Therapy Effect by Spaciotemporal Control of Expressed Proteins YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 11, 1505-1511 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 11, 1505-1511 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 11, 1505-1511 2010/11 Refereed Japanese Disclose to all
Yuki Takahashi, Elin Vikman, Makiya Nishikawa, Mitsuru Ando, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Elin Vikman, Makiya Nishikawa, Mitsuru Ando, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Elin Vikman, Makiya Nishikawa, Mitsuru Ando, Yoshihiko Watanabe, Yoshinobu Takakura Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors JOURNAL OF GENE MEDICINE, 12, 9, 739-746 JOURNAL OF GENE MEDICINE, 12, 9, 739-746 JOURNAL OF GENE MEDICINE, 12, 9, 739-746 2010/09 Refereed English Research paper(scientific journal) Disclose to all
Seiji Takemoto, Makiya Nishikawa, Xin Guan, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Seiji Takemoto, Makiya Nishikawa, Xin Guan, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Seiji Takemoto, Makiya Nishikawa, Xin Guan, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Enhanced Generation of Cytotoxic T Lymphocytes by Heat Shock Protein 70 Fusion Proteins Harboring Both CD8(+) T Cell and CD4(+) T Cell Epitopes Enhanced Generation of Cytotoxic T Lymphocytes by Heat Shock Protein 70 Fusion Proteins Harboring Both CD8(+) T Cell and CD4(+) T Cell Epitopes Enhanced Generation of Cytotoxic T Lymphocytes by Heat Shock Protein 70 Fusion Proteins Harboring Both CD8(+) T Cell and CD4(+) T Cell Epitopes MOLECULAR PHARMACEUTICS, 7, 5, 1715-1723 MOLECULAR PHARMACEUTICS, 7, 5, 1715-1723 MOLECULAR PHARMACEUTICS, 7, 5, 1715-1723 2010/09 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Sakulrat Rattanakiat, Yoshinobu Takakura Makiya Nishikawa, Sakulrat Rattanakiat, Yoshinobu Takakura Makiya Nishikawa, Sakulrat Rattanakiat, Yoshinobu Takakura DNA-based nano-sized systems for pharmaceutical and biomedical applications DNA-based nano-sized systems for pharmaceutical and biomedical applications DNA-based nano-sized systems for pharmaceutical and biomedical applications ADVANCED DRUG DELIVERY REVIEWS, 62, 6, 626-632 ADVANCED DRUG DELIVERY REVIEWS, 62, 6, 626-632 ADVANCED DRUG DELIVERY REVIEWS, 62, 6, 626-632 2010/04 Refereed English Disclose to all
Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshitaka Yano, Yoshinobu Takakura Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshitaka Yano, Yoshinobu Takakura Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshitaka Yano, Yoshinobu Takakura Bootstrap Method-Based Estimation of the Minimum Sample Number for Obtaining Pharmacokinetic Parameters in Preclinical Experiments Bootstrap Method-Based Estimation of the Minimum Sample Number for Obtaining Pharmacokinetic Parameters in Preclinical Experiments Bootstrap Method-Based Estimation of the Minimum Sample Number for Obtaining Pharmacokinetic Parameters in Preclinical Experiments JOURNAL OF PHARMACEUTICAL SCIENCES, 99, 4, 2176-2184 JOURNAL OF PHARMACEUTICAL SCIENCES, 99, 4, 2176-2184 JOURNAL OF PHARMACEUTICAL SCIENCES, 99, 4, 2176-2184 2010/04 Refereed English Research paper(scientific journal) Disclose to all
Ayumi Yamaoka, Xin Guan, Seiji Takemoto, Yoshinobu Takakura Ayumi Yamaoka, Xin Guan, Seiji Takemoto, Yoshinobu Takakura Ayumi Yamaoka, Xin Guan, Seiji Takemoto, Yoshinobu Takakura Development of a novel Hsp70-based DNA vaccine as a multifunctional antigen delivery system Development of a novel Hsp70-based DNA vaccine as a multifunctional antigen delivery system Development of a novel Hsp70-based DNA vaccine as a multifunctional antigen delivery system Journal of Controlled Release, 142, 3, 411-415 Journal of Controlled Release, 142, 3, 411-415 Journal of Controlled Release, 142, 3, 411-415 2010/03/19 Refereed English Research paper(scientific journal) Disclose to all
Kayoko Hattori, Makiya Nishikawa, Kanitta Watcharanurak, Akihiko Ikoma, Kenji Kabashima, Hiroyasu Toyota, Yuki Takahashi, Rei Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura K. Hattori, M. Nishikawa, K. Watcharanurak, A. Ikoma, K. Kabashima, H. Toyota, Y. Takahashi, R. Takahashi, Y. Watanabe, Y. Takakura Kayoko Hattori, Makiya Nishikawa, Kanitta Watcharanurak, Akihiko Ikoma, Kenji Kabashima, Hiroyasu Toyota, Yuki Takahashi, Rei Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Sustained Exogenous Expression of Therapeutic in Levels of IFN-gamma Ameliorates Atopic Dermatitis in NC/Nga Mice via Th1 Polarization Sustained exogenous expression of therapeutic levels of IFN-γ ameliorates atopic dermatitis in NC/Nga mice via Th1 polarization Sustained Exogenous Expression of Therapeutic in Levels of IFN-gamma Ameliorates Atopic Dermatitis in NC/Nga Mice via Th1 Polarization JOURNAL OF IMMUNOLOGY, 184, 5, 2729-2735 Journal of Immunology, 184, 5, 2729-2735 JOURNAL OF IMMUNOLOGY, 184, 5, 2729-2735 2010/03 Refereed English Research paper(scientific journal) Disclose to all
Sachiyo Yasuda, Hiroyuki Yoshida, Makiya Nishikawa, Yoshinobu Takakura Sachiyo Yasuda, Hiroyuki Yoshida, Makiya Nishikawa, Yoshinobu Takakura Sachiyo Yasuda, Hiroyuki Yoshida, Makiya Nishikawa, Yoshinobu Takakura Comparison of the Type of Liposome Involving Cytokine Production Induced by Non-CpG Lipoplex in Macrophages Comparison of the Type of Liposome Involving Cytokine Production Induced by Non-CpG Lipoplex in Macrophages Comparison of the Type of Liposome Involving Cytokine Production Induced by Non-CpG Lipoplex in Macrophages MOLECULAR PHARMACEUTICS, 7, 2, 533-542 MOLECULAR PHARMACEUTICS, 7, 2, 533-542 MOLECULAR PHARMACEUTICS, 7, 2, 533-542 2010/03 Refereed English Research paper(scientific journal) Disclose to all
Xin Guan, Makiya Nishikawa, Seiji Takemoto, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Seiji Takemoto, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Xin Guan, Makiya Nishikawa, Seiji Takemoto, Yuji Ohno, Tomoya Yata, Yoshinobu Takakura Injection site-dependent induction of immune response by DNA vaccine: comparison of skin and spleen as a target for vaccination Injection site-dependent induction of immune response by DNA vaccine: comparison of skin and spleen as a target for vaccination Injection site-dependent induction of immune response by DNA vaccine: comparison of skin and spleen as a target for vaccination JOURNAL OF GENE MEDICINE, 12, 3, 301-309 JOURNAL OF GENE MEDICINE, 12, 3, 301-309 JOURNAL OF GENE MEDICINE, 12, 3, 301-309 2010/03 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Takayuki Otsuki, Atsushi Ota, Xin Guan, Seiji Takemoto, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Takayuki Otsuki, Atsushi Ota, Xin Guan, Seiji Takemoto, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Takayuki Otsuki, Atsushi Ota, Xin Guan, Seiji Takemoto, Yuki Takahashi, Yoshinobu Takakura Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice MOLECULAR THERAPY, 18, 2, 421-428 MOLECULAR THERAPY, 18, 2, 421-428 MOLECULAR THERAPY, 18, 2, 421-428 2010/02 Refereed English Research paper(scientific journal) Disclose to all
Kohta Mohri, Makiya Nishikawa, Yuki Takahaski, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Yuki Takahaski, Yoshinobu Takakura Kohta Mohri, Makiya Nishikawa, Yuki Takahaski, Yoshinobu Takakura Development of oligonucleotide-based nano-sized DDS Development of oligonucleotide-based nano-sized DDS Development of oligonucleotide-based nano-sized DDS Drug Delivery System, 25, 6, 573-578 Drug Delivery System, 25, 6, 573-578 Drug Delivery System, 25, 6, 573-578 2010 Refereed Japanese Disclose to all
Yumiko Mizuno, Tomoyuki Naoi, Makiya Nishikawa, Sakulrat Rattanakiat, Nobuko Hamaguchi, Mitsuru Hashida, Yoshinobu Takakura Yumiko Mizuno, Tomoyuki Naoi, Makiya Nishikawa, Sakulrat Rattanakiat, Nobuko Hamaguchi, Mitsuru Hashida, Yoshinobu Takakura Yumiko Mizuno, Tomoyuki Naoi, Makiya Nishikawa, Sakulrat Rattanakiat, Nobuko Hamaguchi, Mitsuru Hashida, Yoshinobu Takakura Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice JOURNAL OF CONTROLLED RELEASE, 141, 2, 252-259 JOURNAL OF CONTROLLED RELEASE, 141, 2, 252-259 JOURNAL OF CONTROLLED RELEASE, 141, 2, 252-259 2010/01 Refereed English Research paper(scientific journal) Disclose to all
Tomoya Yata, Makiya Nishikawa, Chika Nishizaki, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Yoshinobu Takakura Tomoya Yata, Makiya Nishikawa, Chika Nishizaki, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Yoshinobu Takakura Tomoya Yata, Makiya Nishikawa, Chika Nishizaki, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai, Yoshinobu Takakura Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase FREE RADICAL BIOLOGY AND MEDICINE, 47, 12, 1772-1778 FREE RADICAL BIOLOGY AND MEDICINE, 47, 12, 1772-1778 FREE RADICAL BIOLOGY AND MEDICINE, 47, 12, 1772-1778 2009/12 Refereed English Research paper(scientific journal) Disclose to all
Sakulrat Rattanakiat, Makiya Nishikawa, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura Sakulrat Rattanakiat, Makiya Nishikawa, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura Sakulrat Rattanakiat, Makiya Nishikawa, Hisakage Funabashi, Dan Luo, Yoshinobu Takakura The assembly of a short linear natural cytosine-phosphate-guanine DNA into dendritic structures and its effect on immunostimulatory activity The assembly of a short linear natural cytosine-phosphate-guanine DNA into dendritic structures and its effect on immunostimulatory activity The assembly of a short linear natural cytosine-phosphate-guanine DNA into dendritic structures and its effect on immunostimulatory activity BIOMATERIALS, 30, 29, 5701-5706 BIOMATERIALS, 30, 29, 5701-5706 BIOMATERIALS, 30, 29, 5701-5706 2009/10 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Yumiko Mizuno, Hiroyasu Toyota, Tsuyoshi Kiyota, Rei Takahashi, Yoshinobu Takakura H. Yoshida, M. Nishikawa, S. Yasuda, Y. Mizuno, H. Toyota, T. Kiyota, R. Takahashi, Y. Takakura Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Yumiko Mizuno, Hiroyasu Toyota, Tsuyoshi Kiyota, Rei Takahashi, Yoshinobu Takakura TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice TLR9-dependent systemic interferon-β production by intravenous injection of plasmid DNA/cationic liposome complex in mice TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice JOURNAL OF GENE MEDICINE, 11, 8, 708-717 Journal of Gene Medicine, 11, 8, 708-717 JOURNAL OF GENE MEDICINE, 11, 8, 708-717 2009/08 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 760-766 ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 760-766 ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 760-766 2009/07 Refereed English Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Towards therapeutic application of RNA-mediated gene regulation Preface Towards therapeutic application of RNA-mediated gene regulation Preface Towards therapeutic application of RNA-mediated gene regulation Preface ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 667-667 ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 667-667 ADVANCED DRUG DELIVERY REVIEWS, 61, 9, 667-667 2009/07 Refereed English Disclose to all
Masaru Mitsui, Makiya Nishikawa, Lei Zang, Mitsuru Ando, Kayoko Hattori, Yuki Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Masaru Mitsui, Makiya Nishikawa, Lei Zang, Mitsuru Ando, Kayoko Hattori, Yuki Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Masaru Mitsui, Makiya Nishikawa, Lei Zang, Mitsuru Ando, Kayoko Hattori, Yuki Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression JOURNAL OF GENE MEDICINE, 11, 5, 435-443 JOURNAL OF GENE MEDICINE, 11, 5, 435-443 JOURNAL OF GENE MEDICINE, 11, 5, 435-443 2009/05 Refereed English Research paper(scientific journal) Disclose to all
Masato Maruyama, Kayo Ishida, Yoshihiko Watanabe, Makiya Nishikawa, Yoshinobu Takakura M. Maruyama, K. Ishida, Y. Watanabe, M. Nishikawa, Y. Takakura Masato Maruyama, Kayo Ishida, Yoshihiko Watanabe, Makiya Nishikawa, Yoshinobu Takakura Effects of Methyl-beta-cyclodextrin Treatment on Secretion Profile of Interferon-beta and Zonula Occuludin-1 Architecture in Madin-Darby Canine Kidney Cell Monolayers Effects of methyl-β-cyclodextrin treatment on secretion profile of interferon-/? and zonula occuludin-1 architecture in madin-darby canine kidney cell monolayers Effects of Methyl-beta-cyclodextrin Treatment on Secretion Profile of Interferon-beta and Zonula Occuludin-1 Architecture in Madin-Darby Canine Kidney Cell Monolayers BIOLOGICAL & PHARMACEUTICAL BULLETIN, 32, 5, 910-915 Biological and Pharmaceutical Bulletin, 32, 5, 910-915 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 32, 5, 910-915 2009/05 Refereed English Research paper(scientific journal) Disclose to all
Keiko Isaji, Atsushi Kawase, Mitsuhiro Matono, Xin Guan, Makiya Nishikawa, Yoshinobu Takakura Keiko Isaji, Atsushi Kawase, Mitsuhiro Matono, Xin Guan, Makiya Nishikawa, Yoshinobu Takakura Keiko Isaji, Atsushi Kawase, Mitsuhiro Matono, Xin Guan, Makiya Nishikawa, Yoshinobu Takakura Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination JOURNAL OF CONTROLLED RELEASE, 135, 3, 227-233 JOURNAL OF CONTROLLED RELEASE, 135, 3, 227-233 JOURNAL OF CONTROLLED RELEASE, 135, 3, 227-233 2009/05 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Mitsuru Hashida, Yoshinobu Takakura Makiya Nishikawa, Mitsuru Hashida, Yoshinobu Takakura Makiya Nishikawa, Mitsuru Hashida, Yoshinobu Takakura Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis ADVANCED DRUG DELIVERY REVIEWS, 61, 4, 319-326 ADVANCED DRUG DELIVERY REVIEWS, 61, 4, 319-326 ADVANCED DRUG DELIVERY REVIEWS, 61, 4, 319-326 2009/04 Refereed English Disclose to all
Seiji Takemoto, Makiya Nishikawa, Takayuki Otsuki, Ayumi Yamaoka, Kazuki Maeda, Atsushi Ota, Yoshinobu Takakura Seiji Takemoto, Makiya Nishikawa, Takayuki Otsuki, Ayumi Yamaoka, Kazuki Maeda, Atsushi Ota, Yoshinobu Takakura Seiji Takemoto, Makiya Nishikawa, Takayuki Otsuki, Ayumi Yamaoka, Kazuki Maeda, Atsushi Ota, Yoshinobu Takakura Enhanced generation of cytotoxic T lymphocytes by increased cytosolic delivery of MHC class I epitope fused to mouse heat shock protein 70 via polyhistidine conjugation Enhanced generation of cytotoxic T lymphocytes by increased cytosolic delivery of MHC class I epitope fused to mouse heat shock protein 70 via polyhistidine conjugation Enhanced generation of cytotoxic T lymphocytes by increased cytosolic delivery of MHC class I epitope fused to mouse heat shock protein 70 via polyhistidine conjugation JOURNAL OF CONTROLLED RELEASE, 135, 1, 11-18 JOURNAL OF CONTROLLED RELEASE, 135, 1, 11-18 JOURNAL OF CONTROLLED RELEASE, 135, 1, 11-18 2009/04 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Quantitative and Temporal Analysis of Gene Silencing in Tumor Cells Induced by Small Interfering RNA or Short Hairpin RNA Expressed from Plasmid Vectors Quantitative and Temporal Analysis of Gene Silencing in Tumor Cells Induced by Small Interfering RNA or Short Hairpin RNA Expressed from Plasmid Vectors Quantitative and Temporal Analysis of Gene Silencing in Tumor Cells Induced by Small Interfering RNA or Short Hairpin RNA Expressed from Plasmid Vectors JOURNAL OF PHARMACEUTICAL SCIENCES, 98, 1, 74-80 JOURNAL OF PHARMACEUTICAL SCIENCES, 98, 1, 74-80 JOURNAL OF PHARMACEUTICAL SCIENCES, 98, 1, 74-80 2009/01 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Tetsuya Suehara, Naomi Takiguchi, Yoshinobu Takakura Y. Takahashi, M. Nishikawa, T. Suehara, N. Takiguchi, Y. Takakura Yuki Takahashi, Makiya Nishikawa, Tetsuya Suehara, Naomi Takiguchi, Yoshinobu Takakura Gene silencing of beta-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice Gene silencing of β-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice Gene silencing of beta-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice INTERNATIONAL JOURNAL OF CANCER, 123, 10, 2315-2320 International Journal of Cancer, 123, 10, 2315-2320 INTERNATIONAL JOURNAL OF CANCER, 123, 10, 2315-2320 2008/11 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Ayumi Nakayama, Yuki Takahashi, Yasushi Fukuhara, Yoshinobu Takakura Makiya Nishikawa, Ayumi Nakayama, Yuki Takahashi, Yasushi Fukuhara, Yoshinobu Takakura Makiya Nishikawa, Ayumi Nakayama, Yuki Takahashi, Yasushi Fukuhara, Yoshinobu Takakura Reactivation of Silenced Transgene Expression in Mouse Liver by Rapid, Large-Volume Injection of Isotonic Solution Reactivation of Silenced Transgene Expression in Mouse Liver by Rapid, Large-Volume Injection of Isotonic Solution Reactivation of Silenced Transgene Expression in Mouse Liver by Rapid, Large-Volume Injection of Isotonic Solution HUMAN GENE THERAPY, 19, 10, 1009-1020 HUMAN GENE THERAPY, 19, 10, 1009-1020 HUMAN GENE THERAPY, 19, 10, 1009-1020 2008/10 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Yumiko Mizuno, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Yumiko Mizuno, Yoshinobu Takakura Hiroyuki Yoshida, Makiya Nishikawa, Sachiyo Yasuda, Yumiko Mizuno, Yoshinobu Takakura Cellular activation by plasmid DNA in various macrophages in primary culture Cellular activation by plasmid DNA in various macrophages in primary culture Cellular activation by plasmid DNA in various macrophages in primary culture JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 10, 4575-4585 JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 10, 4575-4585 JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 10, 4575-4585 2008/10 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshinobu Takakura Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells CANCER SCIENCE, 99, 8, 1650-1655 CANCER SCIENCE, 99, 8, 1650-1655 CANCER SCIENCE, 99, 8, 1650-1655 2008/08 Refereed English Research paper(scientific journal) Disclose to all
Keiko Kako, Makiya Nishikawa, Hiroyuki Yoshida, Yoshinobu Takakura Keiko Kako, Makiya Nishikawa, Hiroyuki Yoshida, Yoshinobu Takakura Keiko Kako, Makiya Nishikawa, Hiroyuki Yoshida, Yoshinobu Takakura Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 8, 3074-3083 JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 8, 3074-3083 JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 8, 3074-3083 2008/08 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Mitsuhiro Matono, Sakulrat Rattanakiat, Nao Matsuoka, Yoshinobu Takakura Makiya Nishikawa, Mitsuhiro Matono, Sakulrat Rattanakiat, Nao Matsuoka, Yoshinobu Takakura Makiya Nishikawa, Mitsuhiro Matono, Sakulrat Rattanakiat, Nao Matsuoka, Yoshinobu Takakura Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation IMMUNOLOGY, 124, 2, 247-255 IMMUNOLOGY, 124, 2, 247-255 IMMUNOLOGY, 124, 2, 247-255 2008/06 Refereed English Research paper(scientific journal) Disclose to all
Yoshiyuki Ogawa, Takaharu Yoshinaga, Makiya Nishikawa, Yoshinobu Takakura Yoshiyuki Ogawa, Takaharu Yoshinaga, Makiya Nishikawa, Yoshinobu Takakura Yoshiyuki Ogawa, Takaharu Yoshinaga, Makiya Nishikawa, Yoshinobu Takakura Unique cytokine production profile following stimulation with DNA in macrophages from NZB/W F-1 mice Unique cytokine production profile following stimulation with DNA in macrophages from NZB/W F-1 mice Unique cytokine production profile following stimulation with DNA in macrophages from NZB/W F-1 mice BIOLOGICAL & PHARMACEUTICAL BULLETIN, 31, 6, 1244-1249 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 31, 6, 1244-1249 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 31, 6, 1244-1249 2008/06 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Pharmacokinetic considerations regarding non-viral cancer gene therapy Pharmacokinetic considerations regarding non-viral cancer gene therapy Pharmacokinetic considerations regarding non-viral cancer gene therapy CANCER SCIENCE, 99, 5, 856-862 CANCER SCIENCE, 99, 5, 856-862 CANCER SCIENCE, 99, 5, 856-862 2008/05 Refereed English Disclose to all
Makiya Nishikawa, Seiji Takemoto, Yoshinobu Takakura Makiya Nishikawa, Seiji Takemoto, Yoshinobu Takakura Makiya Nishikawa, Seiji Takemoto, Yoshinobu Takakura Heat shock protein derivatives for delivery of antigens to antigen presenting cells Heat shock protein derivatives for delivery of antigens to antigen presenting cells Heat shock protein derivatives for delivery of antigens to antigen presenting cells INTERNATIONAL JOURNAL OF PHARMACEUTICS, 354, 1-2, 23-27 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 354, 1-2, 23-27 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 354, 1-2, 23-27 2008/04 Refereed English Disclose to all
Y. Takahashi, M. Nishikawa, Y. Takakura Y. Takahashi, M. Nishikawa, Y. Takakura Y. Takahashi, M. Nishikawa, Y. Takakura Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1 alpha expression in tumor cells and hepatocytes Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1α expression in tumor cells and hepatocytes Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1 alpha expression in tumor cells and hepatocytes GENE THERAPY, 15, 8, 572-582 Gene Therapy, 15, 8, 572-582 GENE THERAPY, 15, 8, 572-582 2008/04 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Erratum: (Cancer Science (2008) (1650)) Erratum: (Cancer Science (2008) (1650)) Erratum: (Cancer Science (2008) (1650)) Cancer Science, 99, 10, 2106 Cancer Science, 99, 10, 2106 Cancer Science, 99, 10, 2106 2008 Refereed English Research paper(scientific journal) Disclose to all
Kazuhiro Hirata, Makiya Nishikawa, Naoki Kobayashi, Yuki Takahashi, Yoshinobu Takakura Kazuhiro Hirata, Makiya Nishikawa, Naoki Kobayashi, Yuki Takahashi, Yoshinobu Takakura Kazuhiro Hirata, Makiya Nishikawa, Naoki Kobayashi, Yuki Takahashi, Yoshinobu Takakura Design of PCR-amplified DNA fragments for in vivo gene delivery: Size-dependency on stability and transgene expression Design of PCR-amplified DNA fragments for in vivo gene delivery: Size-dependency on stability and transgene expression Design of PCR-amplified DNA fragments for in vivo gene delivery: Size-dependency on stability and transgene expression JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 9, 2251-2261 JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 9, 2251-2261 JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 9, 2251-2261 2007/09 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Seiji Takemoto, Makiya Nishikawa Yoshinobu Takakura, Seiji Takemoto, Makiya Nishikawa Yoshinobu Takakura, Seiji Takemoto, Makiya Nishikawa Hsp-based tumor vaccines: State-of-the-art and future directions Hsp-based tumor vaccines: State-of-the-art and future directions Hsp-based tumor vaccines: State-of-the-art and future directions CURRENT OPINION IN MOLECULAR THERAPEUTICS, 9, 4, 385-391 CURRENT OPINION IN MOLECULAR THERAPEUTICS, 9, 4, 385-391 CURRENT OPINION IN MOLECULAR THERAPEUTICS, 9, 4, 385-391 2007/08 Refereed English Disclose to all
Hiroki Kawano, Makiya Nishikawa, Masaru Mitsui, Yuki Takahashi, Keiko Kako, Kiyoshi Yamaoka, Yoshihiko Watanabe, Yoshinobu Takakura Hiroki Kawano, Makiya Nishikawa, Masaru Mitsui, Yuki Takahashi, Keiko Kako, Kiyoshi Yamaoka, Yoshihiko Watanabe, Yoshinobu Takakura Hiroki Kawano, Makiya Nishikawa, Masaru Mitsui, Yuki Takahashi, Keiko Kako, Kiyoshi Yamaoka, Yoshihiko Watanabe, Yoshinobu Takakura Improved anti-cancer effect of interferon gene transfer by sustained expression using CpG-reduced plasmid DNA Improved anti-cancer effect of interferon gene transfer by sustained expression using CpG-reduced plasmid DNA Improved anti-cancer effect of interferon gene transfer by sustained expression using CpG-reduced plasmid DNA INTERNATIONAL JOURNAL OF CANCER, 121, 2, 401-406 INTERNATIONAL JOURNAL OF CANCER, 121, 2, 401-406 INTERNATIONAL JOURNAL OF CANCER, 121, 2, 401-406 2007/07 Refereed English Research paper(scientific journal) Disclose to all
Yuga Fukuhara, Tomoyuki Naoi, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura Yuga Fukuhara, Tomoyuki Naoi, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura Yuga Fukuhara, Tomoyuki Naoi, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura Plasmid DNA uptake and subsequent cellular activation characteristics in human monocyte-derived cells in primary culture Plasmid DNA uptake and subsequent cellular activation characteristics in human monocyte-derived cells in primary culture Plasmid DNA uptake and subsequent cellular activation characteristics in human monocyte-derived cells in primary culture JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 6, 1576-1584 JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 6, 1576-1584 JOURNAL OF PHARMACEUTICAL SCIENCES, 96, 6, 1576-1584 2007/06 Refereed English Research paper(scientific journal) Disclose to all
Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kyoko Sano, Hideto Yamaguchi, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kyoko Sano, Hideto Yamaguchi, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kyoko Sano, Hideto Yamaguchi, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL 11) by chemical modification with polyethylene glycol Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL 11) by chemical modification with polyethylene glycol Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL 11) by chemical modification with polyethylene glycol JOURNAL OF CONTROLLED RELEASE, 119, 3, 271-278 JOURNAL OF CONTROLLED RELEASE, 119, 3, 271-278 JOURNAL OF CONTROLLED RELEASE, 119, 3, 271-278 2007/06 Refereed English Research paper(scientific journal) Disclose to all
Yuichi Imura, Minoru Nishida, Yoshiyuki Ogawa, Yoshinobu Takakura, Katsumi Matsuzaki Yuichi Imura, Minoru Nishida, Yoshiyuki Ogawa, Yoshinobu Takakura, Katsumi Matsuzaki Yuichi Imura, Minoru Nishida, Yoshiyuki Ogawa, Yoshinobu Takakura, Katsumi Matsuzaki Action mechanism of tachyplesin I and effects of PEGylation Action mechanism of tachyplesin I and effects of PEGylation Action mechanism of tachyplesin I and effects of PEGylation BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1768, 5, 1160-1169 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1768, 5, 1160-1169 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1768, 5, 1160-1169 2007/05 Refereed English Research paper(scientific journal) Disclose to all
Imura Y, Nishida M, Ogawa Y, Takakura Y, Matsuzaki K Imura Y, Nishida M, Ogawa Y, Takakura Y, Matsuzaki K Imura Y, Nishida M, Ogawa Y, Takakura Y, Matsuzaki K Action mechanism of tachyplesin I and effects of PEGylation. Action mechanism of tachyplesin I and effects of PEGylation. Action mechanism of tachyplesin I and effects of PEGylation. Biochimica et biophysica acta, 1768, 5, 1160-1169 Biochimica et biophysica acta, 1768, 5, 1160-1169 Biochimica et biophysica acta, 1768, 5, 1160-1169 2007/05 Refereed English Disclose to all
Takaharu Yoshinaga, Kei Yasuda, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura Takaharu Yoshinaga, Kei Yasuda, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura Takaharu Yoshinaga, Kei Yasuda, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells IMMUNOLOGY, 120, 3, 295-302 IMMUNOLOGY, 120, 3, 295-302 IMMUNOLOGY, 120, 3, 295-302 2007/03 Refereed English Research paper(scientific journal) Disclose to all
Susumu Nagayama, Ken-ichi Ogawara, Keiko Minato, Yoshiko Fukuoka, Yoshinobu Takakura, Mitsuru Hashida, Kazutaka Higaki, Toshikiro Kimura Susumu Nagayama, Ken-ichi Ogawara, Keiko Minato, Yoshiko Fukuoka, Yoshinobu Takakura, Mitsuru Hashida, Kazutaka Higaki, Toshikiro Kimura Susumu Nagayama, Ken-ichi Ogawara, Keiko Minato, Yoshiko Fukuoka, Yoshinobu Takakura, Mitsuru Hashida, Kazutaka Higaki, Toshikiro Kimura Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor INTERNATIONAL JOURNAL OF PHARMACEUTICS, 329, 1-2, 192-198 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 329, 1-2, 192-198 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 329, 1-2, 192-198 2007/02 Refereed English Research paper(scientific journal) Disclose to all
Hatakeyama Hiroto, Takahashi Yuki, NISHIKAWA Makiya, TAKAKURA Yoshinobu Hatakeyama Hiroto, Takahashi Yuki, NISHIKAWA Makiya, TAKAKURA Yoshinobu Hatakeyama Hiroto, Takahashi Yuki, NISHIKAWA Makiya, TAKAKURA Yoshinobu Novel material and strategy for gene delivery Novel material and strategy for gene delivery Novel material and strategy for gene delivery JOURNAL-PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1523 JOURNAL-PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1523 JOURNAL-PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1523 2007 Refereed Disclose to all
Makiya Nishikawa, Seiii Takemoto, Yoshinobu Takakura Makiya Nishikawa, Seiii Takemoto, Yoshinobu Takakura Makiya Nishikawa, Seiii Takemoto, Yoshinobu Takakura Development of heat shock proteins with controlled distribution properties and their application to vaccine delivery Development of heat shock proteins with controlled distribution properties and their application to vaccine delivery Development of heat shock proteins with controlled distribution properties and their application to vaccine delivery YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 2, 293-300 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 2, 293-300 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 2, 293-300 2007 Refereed Japanese Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura In vivo siRNA delivery to tumor cells and its application to cancer gene therapy In vivo siRNA delivery to tumor cells and its application to cancer gene therapy In vivo siRNA delivery to tumor cells and its application to cancer gene therapy YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1525-1531 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1525-1531 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 127, 10, 1525-1531 2007 Refereed Japanese Disclose to all
Yasuomi Yamasaki, Tomoko Ikenaga, Takayuki Otsuki, Makiya Nishikawa, Yoshinobu Takakura Yasuomi Yamasaki, Tomoko Ikenaga, Takayuki Otsuki, Makiya Nishikawa, Yoshinobu Takakura Yasuomi Yamasaki, Tomoko Ikenaga, Takayuki Otsuki, Makiya Nishikawa, Yoshinobu Takakura Induction of antigen-specific cytotoxic T lymphocytes by immunization with negatively charged soluble antigen through scavenger receptor-mediated delivery Induction of antigen-specific cytotoxic T lymphocytes by immunization with negatively charged soluble antigen through scavenger receptor-mediated delivery Induction of antigen-specific cytotoxic T lymphocytes by immunization with negatively charged soluble antigen through scavenger receptor-mediated delivery VACCINE, 25, 1, 85-91 VACCINE, 25, 1, 85-91 VACCINE, 25, 1, 85-91 2007/01 Refereed English Research paper(scientific journal) Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1 alpha Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1 alpha Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1 alpha JOURNAL OF CONTROLLED RELEASE, 116, 1, 90-95 JOURNAL OF CONTROLLED RELEASE, 116, 1, 90-95 JOURNAL OF CONTROLLED RELEASE, 116, 1, 90-95 2006/11 Refereed English Research paper(scientific journal) Disclose to all
Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kiyo Nakanishi, Shigeo Takemura, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kiyo Nakanishi, Shigeo Takemura, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Noboru Yamashita, Tatsunobu Yoshioka, Yuuki Takaishi, Kiyo Nakanishi, Shigeo Takemura, Atsushi Maeda, Katsumi Saito, Yoshinobu Takakura, Mitsuru Hashida Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL 11) Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL 11) Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL 11) JOURNAL OF CONTROLLED RELEASE, 115, 2, 134-139 JOURNAL OF CONTROLLED RELEASE, 115, 2, 134-139 JOURNAL OF CONTROLLED RELEASE, 115, 2, 134-139 2006/10 Refereed English Research paper(scientific journal) Disclose to all
Atsushi Kawase, Keiko Isaji, Ayumi Yamaoka, Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Atsushi Kawase, Keiko Isaji, Ayumi Yamaoka, Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Atsushi Kawase, Keiko Isaji, Ayumi Yamaoka, Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Enhanced antigen-specific antibody production following polyplex-based DNA vaccination via the intradermal route in mice Enhanced antigen-specific antibody production following polyplex-based DNA vaccination via the intradermal route in mice Enhanced antigen-specific antibody production following polyplex-based DNA vaccination via the intradermal route in mice VACCINE, 24, 27-28, 5535-5545 VACCINE, 24, 27-28, 5535-5545 VACCINE, 24, 27-28, 5535-5545 2006/07 Refereed English Research paper(scientific journal) Disclose to all
Y Takahashi, K Yamaoka, M Nishikawa, Y Takakura Y Takahashi, K Yamaoka, M Nishikawa, Y Takakura Y Takahashi, K Yamaoka, M Nishikawa, Y Takakura Moment analysis for kinetics of gene silencing by RNA interference Moment analysis for kinetics of gene silencing by RNA interference Moment analysis for kinetics of gene silencing by RNA interference BIOTECHNOLOGY AND BIOENGINEERING, 93, 4, 816-819 BIOTECHNOLOGY AND BIOENGINEERING, 93, 4, 816-819 BIOTECHNOLOGY AND BIOENGINEERING, 93, 4, 816-819 2006/03 Refereed English Research paper(scientific journal) Disclose to all
Kei Yasuda, Hermann Wagner, Yoshinobu Takakura Kei Yasuda, Hermann Wagner, Yoshinobu Takakura Kei Yasuda, Hermann Wagner, Yoshinobu Takakura Role of immunostimulatory DNA and TLR9 in gene therapy Role of immunostimulatory DNA and TLR9 in gene therapy Role of immunostimulatory DNA and TLR9 in gene therapy CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 23, 2, 89-109 CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 23, 2, 89-109 CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 23, 2, 89-109 2006 Refereed English Disclose to all
Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Seiji Takemoto, Kiyoshi Yamaoka, Makiya Nishikawa, Yoshinobu Takakura Histogram analysis of pharmacokinetic parameters by bootstrap resampling from one-point sampling data in animal experiments Histogram analysis of pharmacokinetic parameters by bootstrap resampling from one-point sampling data in animal experiments Histogram analysis of pharmacokinetic parameters by bootstrap resampling from one-point sampling data in animal experiments DRUG METABOLISM AND PHARMACOKINETICS, 21, 6, 458-464 DRUG METABOLISM AND PHARMACOKINETICS, 21, 6, 458-464 DRUG METABOLISM AND PHARMACOKINETICS, 21, 6, 458-464 2006 Refereed English Research paper(scientific journal) Disclose to all
Y Matsui, N Kobayashi, M Nishikawa, Y Takakura Y Matsui, N Kobayashi, M Nishikawa, Y Takakura Y Matsui, N Kobayashi, M Nishikawa, Y Takakura Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference PHARMACEUTICAL RESEARCH, 22, 12, 2091-2098 PHARMACEUTICAL RESEARCH, 22, 12, 2091-2098 PHARMACEUTICAL RESEARCH, 22, 12, 2091-2098 2005/12 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, K Hyoudou, Y Kobayashi, Y Umeyama, Y Takakura, M Hashida M Nishikawa, K Hyoudou, Y Kobayashi, Y Umeyama, Y Takakura, M Hashida M Nishikawa, K Hyoudou, Y Kobayashi, Y Umeyama, Y Takakura, M Hashida Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes JOURNAL OF CONTROLLED RELEASE, 109, 1-3, 101-107 JOURNAL OF CONTROLLED RELEASE, 109, 1-3, 101-107 JOURNAL OF CONTROLLED RELEASE, 109, 1-3, 101-107 2005/12 Refereed English Research paper(scientific journal) Disclose to all
Yamane, I, M Nishikawa, Y Takakura Yamane, I, M Nishikawa, Y Takakura Yamane, I, M Nishikawa, Y Takakura Cellular uptake and activation characteristics of naked plasmid DNA and its cationic liposome complex in human macrophages Cellular uptake and activation characteristics of naked plasmid DNA and its cationic liposome complex in human macrophages Cellular uptake and activation characteristics of naked plasmid DNA and its cationic liposome complex in human macrophages INTERNATIONAL JOURNAL OF PHARMACEUTICS, 305, 1-2, 145-153 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 305, 1-2, 145-153 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 305, 1-2, 145-153 2005/11 Refereed English Research paper(scientific journal) Disclose to all
Y Ogawa, T Yoshinaga, K Yasuda, M Nishikawa, Y Takakura Y Ogawa, T Yoshinaga, K Yasuda, M Nishikawa, Y Takakura Y Ogawa, T Yoshinaga, K Yasuda, M Nishikawa, Y Takakura The uptake and degradation of DNA is impaired in macrophages and dendritic cells from NZB/W F-1 mice The uptake and degradation of DNA is impaired in macrophages and dendritic cells from NZB/W F-1 mice The uptake and degradation of DNA is impaired in macrophages and dendritic cells from NZB/W F-1 mice IMMUNOLOGY LETTERS, 101, 1, 32-40 IMMUNOLOGY LETTERS, 101, 1, 32-40 IMMUNOLOGY LETTERS, 101, 1, 32-40 2005/10 Refereed English Research paper(scientific journal) Disclose to all
Y Takahashi, M Nishikawa, N Kobayashi, Y Takakura Y Takahashi, M Nishikawa, N Kobayashi, Y Takakura Y Takahashi, M Nishikawa, N Kobayashi, Y Takakura Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: Quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: Quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: Quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases JOURNAL OF CONTROLLED RELEASE, 105, 3, 332-343 JOURNAL OF CONTROLLED RELEASE, 105, 3, 332-343 JOURNAL OF CONTROLLED RELEASE, 105, 3, 332-343 2005/07 Refereed English Research paper(scientific journal) Disclose to all
M Maruyama, M Kishimoto, K Ishida, Y Watanabe, M Nishikawa, S Masuda, R Sasaki, Y Takakura M Maruyama, M Kishimoto, K Ishida, Y Watanabe, M Nishikawa, S Masuda, R Sasaki, Y Takakura M Maruyama, M Kishimoto, K Ishida, Y Watanabe, M Nishikawa, S Masuda, R Sasaki, Y Takakura Cholesterol is required for the polarized secretion of erythropoietin in Madin-Darby canine kidney cells Cholesterol is required for the polarized secretion of erythropoietin in Madin-Darby canine kidney cells Cholesterol is required for the polarized secretion of erythropoietin in Madin-Darby canine kidney cells ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 438, 2, 174-181 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 438, 2, 174-181 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 438, 2, 174-181 2005/06 Refereed English Research paper(scientific journal) Disclose to all
Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura Gene Therapy and Gene Delivery Gene Therapy and Gene Delivery Gene Therapy and Gene Delivery Drug Delivery: Principles and Applications, 305-319 Drug Delivery: Principles and Applications, 305-319 Drug Delivery: Principles and Applications, 305-319 2005/05/13 Refereed English Disclose to all
A Kawase, N Kobayashi, K Isaji, M Nishikawa, Y Takakura A Kawase, N Kobayashi, K Isaji, M Nishikawa, Y Takakura A Kawase, N Kobayashi, K Isaji, M Nishikawa, Y Takakura Manipulation of local disposition and gene expression characteristics of plasmid DNA following intramuscular administration by complexation with cationic macromolecule Manipulation of local disposition and gene expression characteristics of plasmid DNA following intramuscular administration by complexation with cationic macromolecule Manipulation of local disposition and gene expression characteristics of plasmid DNA following intramuscular administration by complexation with cationic macromolecule INTERNATIONAL JOURNAL OF PHARMACEUTICS, 293, 1-2, 291-301 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 293, 1-2, 291-301 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 293, 1-2, 291-301 2005/04 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida Theoretical considerations involving the pharmacokinetics of plasmid DNA Theoretical considerations involving the pharmacokinetics of plasmid DNA Theoretical considerations involving the pharmacokinetics of plasmid DNA ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 675-688 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 675-688 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 675-688 2005/04 Refereed English Disclose to all
N Kobayashi, M Nishikawa, Y Takakura N Kobayashi, M Nishikawa, Y Takakura N Kobayashi, M Nishikawa, Y Takakura The hydrodynamics-based procedure for controlling the pharmacokinetics of gene medicines at whole body, organ and cellular levels The hydrodynamics-based procedure for controlling the pharmacokinetics of gene medicines at whole body, organ and cellular levels The hydrodynamics-based procedure for controlling the pharmacokinetics of gene medicines at whole body, organ and cellular levels ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 713-731 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 713-731 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 713-731 2005/04 Refereed English Disclose to all
Y Takakura, M Hashida Y Takakura, M Hashida Y Takakura, M Hashida Pharmacokinetics in gene delivery Pharmacokinetics in gene delivery Pharmacokinetics in gene delivery ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 667-668 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 667-668 ADVANCED DRUG DELIVERY REVIEWS, 57, 5, 667-668 2005/04 Refereed English Disclose to all
S Takemoto, M Nishikawa, Y Takakura S Takemoto, M Nishikawa, Y Takakura S Takemoto, M Nishikawa, Y Takakura Pharmacokinetic and tissue distribution mechanism of mouse recombinant heat shock protein 70 in mice Pharmacokinetic and tissue distribution mechanism of mouse recombinant heat shock protein 70 in mice Pharmacokinetic and tissue distribution mechanism of mouse recombinant heat shock protein 70 in mice PHARMACEUTICAL RESEARCH, 22, 3, 419-426 PHARMACEUTICAL RESEARCH, 22, 3, 419-426 PHARMACEUTICAL RESEARCH, 22, 3, 419-426 2005/03 Refereed English Research paper(scientific journal) Disclose to all
Fuminori Sakurai, Yoshinobu Takakura, Mitsuru Hashida Fuminori Sakurai, Yoshinobu Takakura, Mitsuru Hashida Fuminori Sakurai, Yoshinobu Takakura, Mitsuru Hashida Evaluation of the immune response after administration of plasmid DNA-non-viral vector complexes Evaluation of the immune response after administration of plasmid DNA-non-viral vector complexes Evaluation of the immune response after administration of plasmid DNA-non-viral vector complexes Non-viral Gene Therapy: Gene Design and Delivery, 339-347 Non-viral Gene Therapy: Gene Design and Delivery, 339-347 Non-viral Gene Therapy: Gene Design and Delivery, 339-347 2005 Refereed English Disclose to all
H Kawaguchi, Y Akazawa, Y Watanabe, Y Takakura H Kawaguchi, Y Akazawa, Y Watanabe, Y Takakura H Kawaguchi, Y Akazawa, Y Watanabe, Y Takakura Permeability modulation of human intestinal Caco-2 cell monolayers by interferons Permeability modulation of human intestinal Caco-2 cell monolayers by interferons Permeability modulation of human intestinal Caco-2 cell monolayers by interferons EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 59, 1, 45-50 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 59, 1, 45-50 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 59, 1, 45-50 2005/01 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine NON-VIRAL VECTORS FOR GENE THERAPY, 2ND EDITION: PART 1, 53, 47-68 NON-VIRAL VECTORS FOR GENE THERAPY, 2ND EDITION: PART 1, 53, 47-68 NON-VIRAL VECTORS FOR GENE THERAPY, 2ND EDITION: PART 1, 53, 47-68 2005 Refereed English Disclose to all
K Yasuda, Y Ogawa, Yamane, I, M Nishikawa, Y Takakura K Yasuda, Y Ogawa, Yamane, I, M Nishikawa, Y Takakura K Yasuda, Y Ogawa, Yamane, I, M Nishikawa, Y Takakura Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways JOURNAL OF LEUKOCYTE BIOLOGY, 77, 1, 71-79 JOURNAL OF LEUKOCYTE BIOLOGY, 77, 1, 71-79 JOURNAL OF LEUKOCYTE BIOLOGY, 77, 1, 71-79 2005/01 Refereed English Research paper(scientific journal) Disclose to all
M Maruyama, T Nishio, T Kato, T Yoshida, C Ishida, Y Watanabe, M Nishikawa, Y Kaneda, Y Takakura M. Maruyama, T. Nishio, T. Kato, T. Yoshida, C. Ishida, Y. Watanabe, M. Nishikawa, Y. Kaneda, Y. Takakura M Maruyama, T Nishio, T Kato, T Yoshida, C Ishida, Y Watanabe, M Nishikawa, Y Kaneda, Y Takakura Subcellular trafficking of exogenously expressed interferon-beta in Madin-Darby canine kidney cells Subcellular trafficking of exogenously expressed interferon-β in Madin-Darby canine kidney cells Subcellular trafficking of exogenously expressed interferon-beta in Madin-Darby canine kidney cells JOURNAL OF CELLULAR PHYSIOLOGY, 201, 1, 117-125 Journal of Cellular Physiology, 201, 1, 117-125 JOURNAL OF CELLULAR PHYSIOLOGY, 201, 1, 117-125 2004/10 Refereed English Research paper(scientific journal) Disclose to all
T Nishio, M Maruyama, T Yoshida, Y Watanabe, M Nishikawa, Y Takakura T. Nishio, M. Maruyama, T. Yoshida, Y. Watanabe, M. Nishikawa, Y. Takakura T Nishio, M Maruyama, T Yoshida, Y Watanabe, M Nishikawa, Y Takakura Secretion mode and subcellular localization of human interferon-beta exogenously expressed in porcine renal epithelial LLC-PK1 cells Secretion mode and subcellular localization of human interferon-β exogenously expressed in porcine renal epithelial LLC-PK<sub>1</sub> cells Secretion mode and subcellular localization of human interferon-beta exogenously expressed in porcine renal epithelial LLC-PK1 cells BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 10, 1653-1655 Biological and Pharmaceutical Bulletin, 27, 10, 1653-1655 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 10, 1653-1655 2004/10 Refereed English Research paper(scientific journal) Disclose to all
M Maruyama, T Nishio, T Yoshida, C Ishida, K Ishida, Y Watanabe, M Nishikawa, Y Takakura M. Maruyama, T. Nishio, T. Yoshida, C. Ishida, K. Ishida, Y. Watanabe, M. Nishikawa, Y. Takakura M Maruyama, T Nishio, T Yoshida, C Ishida, K Ishida, Y Watanabe, M Nishikawa, Y Takakura Simultaneous detection of DsRed2-tagged and EGFP-tagged human beta-interferons in the same single cells Simultaneous detection of DsRed2-tagged and EGFP-tagged human β-interferons in the same single cells Simultaneous detection of DsRed2-tagged and EGFP-tagged human beta-interferons in the same single cells JOURNAL OF CELLULAR BIOCHEMISTRY, 93, 3, 497-502 Journal of Cellular Biochemistry, 93, 3, 497-502 JOURNAL OF CELLULAR BIOCHEMISTRY, 93, 3, 497-502 2004/10 Refereed English Research paper(scientific journal) Disclose to all
M Nakamura, S Yamaguchi, Y Watanabe, F Yamashita, Y Takakura, M Hashida M. Nakamura, S. Yamaguchi, Y. Watanabe, F. Yamashita, Y. Takakura, M. Hashida M Nakamura, S Yamaguchi, Y Watanabe, F Yamashita, Y Takakura, M Hashida Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells Exogenous expression of interferon-β in cultured brain microvessel endothelial cells Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 9, 1441-1443 Biological and Pharmaceutical Bulletin, 27, 9, 1441-1443 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 9, 1441-1443 2004/09 Refereed English Research paper(scientific journal) Disclose to all
J Hisazumi, N Kobayashi, M Nishikawa, Y Takakura J Hisazumi, N Kobayashi, M Nishikawa, Y Takakura J Hisazumi, N Kobayashi, M Nishikawa, Y Takakura Significant role of liver sinusoidal endothelial cells in hepatic uptake and degradation of naked plasmid DNA after intravenous injection Significant role of liver sinusoidal endothelial cells in hepatic uptake and degradation of naked plasmid DNA after intravenous injection Significant role of liver sinusoidal endothelial cells in hepatic uptake and degradation of naked plasmid DNA after intravenous injection PHARMACEUTICAL RESEARCH, 21, 7, 1223-1228 PHARMACEUTICAL RESEARCH, 21, 7, 1223-1228 PHARMACEUTICAL RESEARCH, 21, 7, 1223-1228 2004/07 Refereed English Research paper(scientific journal) Disclose to all
T Ikenaga, Y Yamasaki, K Shakushiro, M Nishikawa, Y Takakura T Ikenaga, Y Yamasaki, K Shakushiro, M Nishikawa, Y Takakura T Ikenaga, Y Yamasaki, K Shakushiro, M Nishikawa, Y Takakura Induction of cytotoxic T lymphocytes following immunization with cationized soluble antigen Induction of cytotoxic T lymphocytes following immunization with cationized soluble antigen Induction of cytotoxic T lymphocytes following immunization with cationized soluble antigen VACCINE, 22, 20, 2609-2616 VACCINE, 22, 20, 2609-2616 VACCINE, 22, 20, 2609-2616 2004/06 Refereed English Research paper(scientific journal) Disclose to all
K Shakushiro, Y Yamasaki, M Nishikawa, Y Takakura K Shakushiro, Y Yamasaki, M Nishikawa, Y Takakura K Shakushiro, Y Yamasaki, M Nishikawa, Y Takakura Efficient scavenger receptor-mediated uptake and cross-presentation of negatively charged soluble antigens by dendritic cells Efficient scavenger receptor-mediated uptake and cross-presentation of negatively charged soluble antigens by dendritic cells Efficient scavenger receptor-mediated uptake and cross-presentation of negatively charged soluble antigens by dendritic cells IMMUNOLOGY, 112, 2, 211-218 IMMUNOLOGY, 112, 2, 211-218 IMMUNOLOGY, 112, 2, 211-218 2004/06 Refereed English Research paper(scientific journal) Disclose to all
K Furumoto, S Nagayama, K Ogawara, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, S Nagayama, K Ogawara, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, S Nagayama, K Ogawara, Y Takakura, M Hashida, K Higaki, T Kimura Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor JOURNAL OF CONTROLLED RELEASE, 97, 1, 133-141 JOURNAL OF CONTROLLED RELEASE, 97, 1, 133-141 JOURNAL OF CONTROLLED RELEASE, 97, 1, 133-141 2004/05 Refereed English Research paper(scientific journal) Disclose to all
N Kobayashi, M Nishikawa, K Hirata, Y Takakura N Kobayashi, M Nishikawa, K Hirata, Y Takakura N Kobayashi, M Nishikawa, K Hirata, Y Takakura Hyrodynamics-based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery Hyrodynamics-based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery Hyrodynamics-based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery JOURNAL OF GENE MEDICINE, 6, 5, 584-592 JOURNAL OF GENE MEDICINE, 6, 5, 584-592 JOURNAL OF GENE MEDICINE, 6, 5, 584-592 2004/05 Refereed English Research paper(scientific journal) Disclose to all
N Kobayashi, K Hirata, S Chen, A Kawase, M Nishikawa, Y Takakura N Kobayashi, K Hirata, S Chen, A Kawase, M Nishikawa, Y Takakura N Kobayashi, K Hirata, S Chen, A Kawase, M Nishikawa, Y Takakura Hepatic delivery of particulates in the submicron range by a hydrodynamics-based procedure: implications for particulate gene delivery systems Hepatic delivery of particulates in the submicron range by a hydrodynamics-based procedure: implications for particulate gene delivery systems Hepatic delivery of particulates in the submicron range by a hydrodynamics-based procedure: implications for particulate gene delivery systems JOURNAL OF GENE MEDICINE, 6, 4, 455-463 JOURNAL OF GENE MEDICINE, 6, 4, 455-463 JOURNAL OF GENE MEDICINE, 6, 4, 455-463 2004/04 Refereed English Research paper(scientific journal) Disclose to all
M Nakamura, M Maruyama, F Yamashita, Y Takakura, M Hashida, Y Watanabe M. Nakamura, M. Maruyama, F. Yamashita, Y. Takakura, M. Hashida, Y. Watanabe M Nakamura, M Maruyama, F Yamashita, Y Takakura, M Hashida, Y Watanabe Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells Expression and visualization of a human interferon-β-enhanced green fluorescent protein chimeric molecule in cultured cells Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 3, 411-414 Biological and Pharmaceutical Bulletin, 27, 3, 411-414 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 27, 3, 411-414 2004/03 Refereed English Research paper(scientific journal) Disclose to all
K Yasuda, H Kawano, Yamane, I, Y Ogawa, T Yoshinaga, M Nishikawa, Y Takakura K Yasuda, H Kawano, Yamane, I, Y Ogawa, T Yoshinaga, M Nishikawa, Y Takakura K Yasuda, H Kawano, Yamane, I, Y Ogawa, T Yoshinaga, M Nishikawa, Y Takakura Restricted cytokine production from mouse peritoneal macrophages in culture in spite of extensive uptake of plasmid DNA Restricted cytokine production from mouse peritoneal macrophages in culture in spite of extensive uptake of plasmid DNA Restricted cytokine production from mouse peritoneal macrophages in culture in spite of extensive uptake of plasmid DNA IMMUNOLOGY, 111, 3, 282-290 IMMUNOLOGY, 111, 3, 282-290 IMMUNOLOGY, 111, 3, 282-290 2004/03 Refereed English Research paper(scientific journal) Disclose to all
N Kobayashi, Y Matsui, A Kawase, K Hirata, M Miyagishi, K Taira, M Nishikawa, Y Takakura N Kobayashi, Y Matsui, A Kawase, K Hirata, M Miyagishi, K Taira, M Nishikawa, Y Takakura N Kobayashi, Y Matsui, A Kawase, K Hirata, M Miyagishi, K Taira, M Nishikawa, Y Takakura Vector-based in vivo RNA interference: Dose- and time-dependent suppression of transgene expression Vector-based in vivo RNA interference: Dose- and time-dependent suppression of transgene expression Vector-based in vivo RNA interference: Dose- and time-dependent suppression of transgene expression JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 308, 2, 688-693 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 308, 2, 688-693 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 308, 2, 688-693 2004/02 Refereed English Research paper(scientific journal) Disclose to all
T Kato, K Yamaoka, Y Takakura T Kato, K Yamaoka, Y Takakura T Kato, K Yamaoka, Y Takakura An evaluation method for nonlinear local disposition in rat liver and kidney An evaluation method for nonlinear local disposition in rat liver and kidney An evaluation method for nonlinear local disposition in rat liver and kidney DRUG METABOLISM AND DISPOSITION, 32, 2, 230-234 DRUG METABOLISM AND DISPOSITION, 32, 2, 230-234 DRUG METABOLISM AND DISPOSITION, 32, 2, 230-234 2004/02 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Sugars and dds Sugars and dds Sugars and dds Drug Delivery System, 19, 1, 28-31 Drug Delivery System, 19, 1, 28-31 Drug Delivery System, 19, 1, 28-31 2004 Refereed English Research paper(scientific journal) Disclose to all
Y Imura, M Nishida, Y Ogawa, Y Takakura, K Matsuzaki Y Imura, M Nishida, Y Ogawa, Y Takakura, K Matsuzaki Y Imura, M Nishida, Y Ogawa, Y Takakura, K Matsuzaki Effects of PEGylation on the activity of tachyplesin I Effects of PEGylation on the activity of tachyplesin I Effects of PEGylation on the activity of tachyplesin I YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 124, 117-120 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 124, 117-120 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 124, 117-120 2004 Refereed English Research paper(scientific journal) Disclose to all
Makiya Nishikawa, Naoki Kobayashi, Yoshinobu Takakura 西川元也, 小林直樹, 高倉喜信 Makiya Nishikawa, Naoki Kobayashi, Yoshinobu Takakura RNAi-based gene silencing in mice RNAiによるマウス個体での遺伝子ノックダウン RNAi-based gene silencing in mice Drug Delivery System, 19, 4, 385-391 Drug Delivery System, 19, 4, 385-391 Drug Delivery System, 19, 4, 385-391 2004 Refereed English Research paper(scientific journal) Disclose to all
Y. Takakura Y. Takakura Y. Takakura Cancer gene therapy - Gene delivery research Cancer gene therapy - Gene delivery research Cancer gene therapy - Gene delivery research Biotherapy, 18, 3, 253-257 Biotherapy, 18, 3, 253-257 Biotherapy, 18, 3, 253-257 2004 Refereed English Disclose to all
K. Yamaoka, Y. Takakura K. Yamaoka, Y. Takakura K. Yamaoka, Y. Takakura Analysis methods and recent advances in nonlinear pharmacokinetics from in vitro through in loci to in vivo. Analysis methods and recent advances in nonlinear pharmacokinetics from in vitro through in loci to in vivo. Analysis methods and recent advances in nonlinear pharmacokinetics from in vitro through in loci to in vivo. Drug metabolism and pharmacokinetics, 19, 6, 397-406 Drug metabolism and pharmacokinetics, 19, 6, 397-406 Drug metabolism and pharmacokinetics, 19, 6, 397-406 2004 Refereed English Disclose to all
M Nishikawa, A Tamada, K Hyoudou, Y Umeyama, Y Takahashi, Y Kobayashi, H Kumai, E Ishida, F Staud, Y Yabe, Y Takakura, F Yamashita, M Hashida M Nishikawa, A Tamada, K Hyoudou, Y Umeyama, Y Takahashi, Y Kobayashi, H Kumai, E Ishida, F Staud, Y Yabe, Y Takakura, F Yamashita, M Hashida M Nishikawa, A Tamada, K Hyoudou, Y Umeyama, Y Takahashi, Y Kobayashi, H Kumai, E Ishida, F Staud, Y Yabe, Y Takakura, F Yamashita, M Hashida Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice CLINICAL & EXPERIMENTAL METASTASIS, 21, 3, 213-221 CLINICAL & EXPERIMENTAL METASTASIS, 21, 3, 213-221 CLINICAL & EXPERIMENTAL METASTASIS, 21, 3, 213-221 2004 Refereed English Research paper(scientific journal) Disclose to all
H Kawaguchi, Y Matsui, Y Watanabe, Y Takakura H. Kawaguchi, Y. Matsui, Y. Watanabe, Y. Takakura H Kawaguchi, Y Matsui, Y Watanabe, Y Takakura Effect of interferon-gamma on the pharmacokinetics of digoxin, a P-glycoprotein substrate, intravenously injected into the mouse Effect of Interferon-γ on the Pharmacokinetics of Digoxin, a P-glycoprotein Substrate, Intravenously Injected into the Mouse Effect of interferon-gamma on the pharmacokinetics of digoxin, a P-glycoprotein substrate, intravenously injected into the mouse JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 308, 1, 91-96 Journal of Pharmacology and Experimental Therapeutics, 308, 1, 91-96 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 308, 1, 91-96 2004/01 Refereed English Research paper(scientific journal) Disclose to all
F Verbaan, van Dam, I, Y Takakura, M Hashida, W Hennink, G Storm, C Oussoren F Verbaan, van Dam, I, Y Takakura, M Hashida, W Hennink, G Storm, C Oussoren F Verbaan, van Dam, I, Y Takakura, M Hashida, W Hennink, G Storm, C Oussoren Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 20, 4-5, 419-427 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 20, 4-5, 419-427 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 20, 4-5, 419-427 2003/12 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, T Nakano, T Okabe, N Hamaguchi, Y Yamasaki, Y Takakura, F Yamashita, M Hashida M Nishikawa, T Nakano, T Okabe, N Hamaguchi, Y Yamasaki, Y Takakura, F Yamashita, M Hashida M Nishikawa, T Nakano, T Okabe, N Hamaguchi, Y Yamasaki, Y Takakura, F Yamashita, M Hashida Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study BIOCONJUGATE CHEMISTRY, 14, 5, 955-961 BIOCONJUGATE CHEMISTRY, 14, 5, 955-961 BIOCONJUGATE CHEMISTRY, 14, 5, 955-961 2003/09 Refereed English Research paper(scientific journal) Disclose to all
F Sakurai, T Terada, M Maruyama, Y Watanabe, F Yamashita, Y Takakura, M Hashida F. Sakurai, T. Terada, M. Maruyama, Y. Watanabe, F. Yamashita, Y. Takakura, M. Hashida F Sakurai, T Terada, M Maruyama, Y Watanabe, F Yamashita, Y Takakura, M Hashida Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I : poly C in a murine lung metastasis model Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-β gene and poly I: Poly C in a murine lung metastasis model Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I : poly C in a murine lung metastasis model CANCER GENE THERAPY, 10, 9, 661-668 Cancer Gene Therapy, 10, 9, 661-668 CANCER GENE THERAPY, 10, 9, 661-668 2003/09 Refereed English Research paper(scientific journal) Disclose to all
RI Mahato, K Kawabata, Y Takakura, M Hashida RI Mahato, K Kawabata, Y Takakura, M Hashida RI Mahato, K Kawabata, Y Takakura, M Hashida In vivo disposition characteristics of plasmid DNA complexed with cationic liposomes In vivo disposition characteristics of plasmid DNA complexed with cationic liposomes In vivo disposition characteristics of plasmid DNA complexed with cationic liposomes JOURNAL OF DRUG TARGETING, 11, 5, 287-294 JOURNAL OF DRUG TARGETING, 11, 5, 287-294 JOURNAL OF DRUG TARGETING, 11, 5, 287-294 2003/06 Refereed English Research paper(scientific journal) Disclose to all
A Kawase, T Nomura, K Yasuda, N Kobayashi, M Hashida, Y Takakura A Kawase, T Nomura, K Yasuda, N Kobayashi, M Hashida, Y Takakura A Kawase, T Nomura, K Yasuda, N Kobayashi, M Hashida, Y Takakura Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice JOURNAL OF PHARMACEUTICAL SCIENCES, 92, 6, 1295-1304 JOURNAL OF PHARMACEUTICAL SCIENCES, 92, 6, 1295-1304 JOURNAL OF PHARMACEUTICAL SCIENCES, 92, 6, 1295-1304 2003/06 Refereed English Research paper(scientific journal) Disclose to all
M Anraku, U Kragh-Hansen, K Kawai, T Maruyama, Y Yamasaki, Y Takakura, M Otagiri M Anraku, U Kragh-Hansen, K Kawai, T Maruyama, Y Yamasaki, Y Takakura, M Otagiri M Anraku, U Kragh-Hansen, K Kawai, T Maruyama, Y Yamasaki, Y Takakura, M Otagiri Validation of the chloramine-T induced oxidation of human serum albumin as a model for oxidative damage in vivo Validation of the chloramine-T induced oxidation of human serum albumin as a model for oxidative damage in vivo Validation of the chloramine-T induced oxidation of human serum albumin as a model for oxidative damage in vivo PHARMACEUTICAL RESEARCH, 20, 4, 684-692 PHARMACEUTICAL RESEARCH, 20, 4, 684-692 PHARMACEUTICAL RESEARCH, 20, 4, 684-692 2003/04 Refereed English Research paper(scientific journal) Disclose to all
Y Yamasaki, J Hisazumi, K Yamaoka, Y Takakura Y Yamasaki, J Hisazumi, K Yamaoka, Y Takakura Y Yamasaki, J Hisazumi, K Yamaoka, Y Takakura Efficient scavenger receptor-mediated hepatic targeting of proteins by introduction of negative charges on the proteins by aconitylation: the influence of charge density and size of the proteins molecules Efficient scavenger receptor-mediated hepatic targeting of proteins by introduction of negative charges on the proteins by aconitylation: the influence of charge density and size of the proteins molecules Efficient scavenger receptor-mediated hepatic targeting of proteins by introduction of negative charges on the proteins by aconitylation: the influence of charge density and size of the proteins molecules EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 18, 5, 305-312 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 18, 5, 305-312 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 18, 5, 305-312 2003/04 Refereed English Research paper(scientific journal) Disclose to all
T Yoshinaga, K Yasuda, Y Ogawa, Y Takakura T Yoshinaga, K Yasuda, Y Ogawa, Y Takakura T Yoshinaga, K Yasuda, Y Ogawa, Y Takakura Efficient uptake and rapid degradation of plasmid DNA by murine dendritic cells via a specific mechanism Efficient uptake and rapid degradation of plasmid DNA by murine dendritic cells via a specific mechanism Efficient uptake and rapid degradation of plasmid DNA by murine dendritic cells via a specific mechanism BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 299, 3, 389-394 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 299, 3, 389-394 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 299, 3, 389-394 2002/12 Refereed English Research paper(scientific journal) Disclose to all
Y Yabe, N Kobayashi, M Nishikawa, K Mihara, F Yamashita, Y Takakura, M Hashida Y Yabe, N Kobayashi, M Nishikawa, K Mihara, F Yamashita, Y Takakura, M Hashida Y Yabe, N Kobayashi, M Nishikawa, K Mihara, F Yamashita, Y Takakura, M Hashida Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver PHARMACEUTICAL RESEARCH, 19, 12, 1815-1821 PHARMACEUTICAL RESEARCH, 19, 12, 1815-1821 PHARMACEUTICAL RESEARCH, 19, 12, 1815-1821 2002/12 Refereed English Research paper(scientific journal) Disclose to all
N Kobayashi, T Kuramoto, S Chen, Y Watanabe, Y Takakura N Kobayashi, T Kuramoto, S Chen, Y Watanabe, Y Takakura N Kobayashi, T Kuramoto, S Chen, Y Watanabe, Y Takakura Therapeutic effect of intravenous interferon gene delivery with naked plasmid DNA in murine metastasis models Therapeutic effect of intravenous interferon gene delivery with naked plasmid DNA in murine metastasis models Therapeutic effect of intravenous interferon gene delivery with naked plasmid DNA in murine metastasis models MOLECULAR THERAPY, 6, 6, 737-744 MOLECULAR THERAPY, 6, 6, 737-744 MOLECULAR THERAPY, 6, 6, 737-744 2002/12 Refereed English Research paper(scientific journal) Disclose to all
Y Akazawa, H Kawaguchi, M Funahashi, Y Watanabe, K Yamaoka, M Hashida, Y Takakura Y Akazawa, H Kawaguchi, M Funahashi, Y Watanabe, K Yamaoka, M Hashida, Y Takakura Y Akazawa, H Kawaguchi, M Funahashi, Y Watanabe, K Yamaoka, M Hashida, Y Takakura Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat Hepatocytes Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat Hepatocytes Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat Hepatocytes JOURNAL OF PHARMACEUTICAL SCIENCES, 91, 10, 2110-2115 JOURNAL OF PHARMACEUTICAL SCIENCES, 91, 10, 2110-2115 JOURNAL OF PHARMACEUTICAL SCIENCES, 91, 10, 2110-2115 2002/10 Refereed English Research paper(scientific journal) Disclose to all
K Furumoto, K Ogawara, S Nagayama, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, K Ogawara, S Nagayama, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, K Ogawara, S Nagayama, Y Takakura, M Hashida, K Higaki, T Kimura Important role of serum proteins associated on the surface of particles in their hepatic disposition Important role of serum proteins associated on the surface of particles in their hepatic disposition Important role of serum proteins associated on the surface of particles in their hepatic disposition JOURNAL OF CONTROLLED RELEASE, 83, 1, 89-96 JOURNAL OF CONTROLLED RELEASE, 83, 1, 89-96 JOURNAL OF CONTROLLED RELEASE, 83, 1, 89-96 2002/09 Refereed English Research paper(scientific journal) Disclose to all
F Sakurai, T Terada, K Yasuda, F Yamashita, Y Takakura, M Hashida F Sakurai, T Terada, K Yasuda, F Yamashita, Y Takakura, M Hashida F Sakurai, T Terada, K Yasuda, F Yamashita, Y Takakura, M Hashida The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes GENE THERAPY, 9, 16, 1120-1126 GENE THERAPY, 9, 16, 1120-1126 GENE THERAPY, 9, 16, 1120-1126 2002/08 Refereed English Research paper(scientific journal) Disclose to all
K Nakanishi, Y Watanabe, M Maruyama, F Yamashita, Y Takakura, M Hashida K. Nakanishi, Y. Watanabe, M. Maruyama, F. Yamashita, Y. Takakura, M. Hashida K Nakanishi, Y Watanabe, M Maruyama, F Yamashita, Y Takakura, M Hashida Secretion polarity of interferon-beta in epithelial cell lines Secretion polarity of interferon-β in epithelial cell lines Secretion polarity of interferon-beta in epithelial cell lines ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 402, 2, 201-207 Archives of Biochemistry and Biophysics, 402, 2, 201-207 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 402, 2, 201-207 2002/06 Refereed English Research paper(scientific journal) Disclose to all
Y Yamasaki, K Sumimoto, M Nishikawa, F Yamashita, K Yamaoka, M Hashida, Y Takakura Y Yamasaki, K Sumimoto, M Nishikawa, F Yamashita, K Yamaoka, M Hashida, Y Takakura Y Yamasaki, K Sumimoto, M Nishikawa, F Yamashita, K Yamaoka, M Hashida, Y Takakura Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: Importance of molecular size and negative charge density for in vivo recognition by receptors Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: Importance of molecular size and negative charge density for in vivo recognition by receptors Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: Importance of molecular size and negative charge density for in vivo recognition by receptors JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 301, 2, 467-477 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 301, 2, 467-477 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 301, 2, 467-477 2002/05 Refereed English Research paper(scientific journal) Disclose to all
K Yasuda, Y Ogawa, M Kishimoto, T Takagi, M Hashida, Y Takakura K Yasuda, Y Ogawa, M Kishimoto, T Takagi, M Hashida, Y Takakura K Yasuda, Y Ogawa, M Kishimoto, T Takagi, M Hashida, Y Takakura Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 293, 1, 344-348 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 293, 1, 344-348 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 293, 1, 344-348 2002/04 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, S Hasegawa, F Yamashita, Y Takakura, M Hashida M Nishikawa, S Hasegawa, F Yamashita, Y Takakura, M Hashida M Nishikawa, S Hasegawa, F Yamashita, Y Takakura, M Hashida Electrical charge on protein regulates its absorption from the rat small intestine Electrical charge on protein regulates its absorption from the rat small intestine Electrical charge on protein regulates its absorption from the rat small intestine AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 282, 4, G711-G719 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 282, 4, G711-G719 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 282, 4, G711-G719 2002/04 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, M Nishikawa, F Yamashita, M Hashida Y Takakura, M Nishikawa, F Yamashita, M Hashida Y Takakura, M Nishikawa, F Yamashita, M Hashida Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery JOURNAL OF DRUG TARGETING, 10, 2, 99-104 JOURNAL OF DRUG TARGETING, 10, 2, 99-104 JOURNAL OF DRUG TARGETING, 10, 2, 99-104 2002/03 Refereed English Research paper(scientific journal) Disclose to all
Akira Takagi, Yoshiyuki Yabe, Yoshikazu Oka, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Yoshiyuki Yabe, Yoshikazu Oka, Yoshinobu Takakura, Mitsuru Hashida Akira Takagi, Yoshiyuki Yabe, Yoshikazu Oka, Yoshinobu Takakura, Mitsuru Hashida Effect of Co-administration of Cationic Macromolecules on the In Vivo Disposition and In situ Renal Disposition Characteristics of rhIL-11 Effect of Co-administration of Cationic Macromolecules on the In Vivo Disposition and In situ Renal Disposition Characteristics of rhIL-11 Effect of Co-administration of Cationic Macromolecules on the In Vivo Disposition and In situ Renal Disposition Characteristics of rhIL-11 Drug Metabolism and Pharmacokinetics, 17, 2, 136-141 Drug Metabolism and Pharmacokinetics, 17, 2, 136-141 Drug Metabolism and Pharmacokinetics, 17, 2, 136-141 2002 Refereed English Research paper(scientific journal) Disclose to all
K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E-1 using lactosylated poly(L-glutamic hydrazide) as a carrier Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E-1 using lactosylated poly(L-glutamic hydrazide) as a carrier Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E-1 using lactosylated poly(L-glutamic hydrazide) as a carrier BIOCHEMICAL PHARMACOLOGY, 62, 11, 1531-1536 BIOCHEMICAL PHARMACOLOGY, 62, 11, 1531-1536 BIOCHEMICAL PHARMACOLOGY, 62, 11, 1531-1536 2001/12 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats JOURNAL OF CONTROLLED RELEASE, 77, 3, 191-198 JOURNAL OF CONTROLLED RELEASE, 77, 3, 191-198 JOURNAL OF CONTROLLED RELEASE, 77, 3, 191-198 2001/12 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, M Nishikawa, F Yamashita, Y Takakura M Hashida, M Nishikawa, F Yamashita, Y Takakura M Hashida, M Nishikawa, F Yamashita, Y Takakura Cell-specific delivery of genes with glycosylated carriers Cell-specific delivery of genes with glycosylated carriers Cell-specific delivery of genes with glycosylated carriers ADVANCED DRUG DELIVERY REVIEWS, 52, 3, 187-196 ADVANCED DRUG DELIVERY REVIEWS, 52, 3, 187-196 ADVANCED DRUG DELIVERY REVIEWS, 52, 3, 187-196 2001/11 Refereed English Disclose to all
Y Yabe, N Kobayashi, T Nishihashi, R Takahashi, M Nishikawa, Y Takakura, M Hashida Y Yabe, N Kobayashi, T Nishihashi, R Takahashi, M Nishikawa, Y Takakura, M Hashida Y Yabe, N Kobayashi, T Nishihashi, R Takahashi, M Nishikawa, Y Takakura, M Hashida Prevention of neutrophil-mediated hepatic ischemia/reperfusion injury by superoxide dismutase and catalase derivatives Prevention of neutrophil-mediated hepatic ischemia/reperfusion injury by superoxide dismutase and catalase derivatives Prevention of neutrophil-mediated hepatic ischemia/reperfusion injury by superoxide dismutase and catalase derivatives JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 298, 3, 894-899 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 298, 3, 894-899 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 298, 3, 894-899 2001/09 Refereed English Research paper(scientific journal) Disclose to all
F Sakurai, T Nishioka, F Yamashita, Y Takakura, M Hashida F Sakurai, T Nishioka, F Yamashita, Y Takakura, M Hashida F Sakurai, T Nishioka, F Yamashita, Y Takakura, M Hashida Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 52, 2, 165-172 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 52, 2, 165-172 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 52, 2, 165-172 2001/09 Refereed English Research paper(scientific journal) Disclose to all
Y Imamura, K Shimizu, F Yamashita, K Yamaoka, Y Takakura, M Hashida Y Imamura, K Shimizu, F Yamashita, K Yamaoka, Y Takakura, M Hashida Y Imamura, K Shimizu, F Yamashita, K Yamaoka, Y Takakura, M Hashida Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers BIOLOGICAL & PHARMACEUTICAL BULLETIN, 24, 8, 930-934 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 24, 8, 930-934 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 24, 8, 930-934 2001/08 Refereed English Research paper(scientific journal) Disclose to all
N Kobayashi, T Kuramoto, K Yamaoka, M Hashida, Y Takakura N Kobayashi, T Kuramoto, K Yamaoka, M Hashida, Y Takakura N Kobayashi, T Kuramoto, K Yamaoka, M Hashida, Y Takakura Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 297, 3, 853-860 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 297, 3, 853-860 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 297, 3, 853-860 2001/06 Refereed English Research paper(scientific journal) Disclose to all
F Sakurai, T Nishioka, H Saito, T Baba, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, T Nishioka, H Saito, T Baba, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, T Nishioka, H Saito, T Baba, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid GENE THERAPY, 8, 9, 677-686 GENE THERAPY, 8, 9, 677-686 GENE THERAPY, 8, 9, 677-686 2001/05 Refereed English Research paper(scientific journal) Disclose to all
P Opanasopit, K Shirashi, M Nishikawa, F Yamashita, Y Takakura, M Hashida P Opanasopit, K Shirashi, M Nishikawa, F Yamashita, Y Takakura, M Hashida P Opanasopit, K Shirashi, M Nishikawa, F Yamashita, Y Takakura, M Hashida In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 280, 5, G879-G889 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 280, 5, G879-G889 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 280, 5, G879-G889 2001/05 Refereed English Research paper(scientific journal) Disclose to all
K Furumoto, K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura K Furumoto, K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1526, 2, 221-226 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1526, 2, 221-226 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1526, 2, 221-226 2001/05 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, M Nishikawa, F Yamashita, M Hashida Y Takakura, M Nishikawa, F Yamashita, M Hashida Y Takakura, M Nishikawa, F Yamashita, M Hashida Development of gene drug delivery systems based on pharmacokinetic studies Development of gene drug delivery systems based on pharmacokinetic studies Development of gene drug delivery systems based on pharmacokinetic studies EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 13, 1, 71-76 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 13, 1, 71-76 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 13, 1, 71-76 2001/04 Refereed English Disclose to all
FJ Verbaan, C Oussoren, IM van Dam, Y Takakura, M Hashida, DJA Crommelin, WE Hennink, G Storm FJ Verbaan, C Oussoren, IM van Dam, Y Takakura, M Hashida, DJA Crommelin, WE Hennink, G Storm FJ Verbaan, C Oussoren, IM van Dam, Y Takakura, M Hashida, DJA Crommelin, WE Hennink, G Storm The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration INTERNATIONAL JOURNAL OF PHARMACEUTICS, 214, 1-2, 99-101 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 214, 1-2, 99-101 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 214, 1-2, 99-101 2001/02 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Drug delivery systems and micromachines Drug delivery systems and micromachines Drug delivery systems and micromachines Drug Delivery System, 16, 2, 71-76 Drug Delivery System, 16, 2, 71-76 Drug Delivery System, 16, 2, 71-76 2001 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Tumor metastasis models Tumor metastasis models Tumor metastasis models Drug Delivery System, 16, 2, 97-105 Drug Delivery System, 16, 2, 97-105 Drug Delivery System, 16, 2, 97-105 2001 Refereed English Research paper(scientific journal) Disclose to all
P Opanasopit, M Nishikawa, F Yamashita, Y Takakura, N Hashida P Opanasopit, M Nishikawa, F Yamashita, Y Takakura, N Hashida P Opanasopit, M Nishikawa, F Yamashita, Y Takakura, N Hashida Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells JOURNAL OF DRUG TARGETING, 9, 5, 341-351 JOURNAL OF DRUG TARGETING, 9, 5, 341-351 JOURNAL OF DRUG TARGETING, 9, 5, 341-351 2001 Refereed English Research paper(scientific journal) Disclose to all
F. Sakurai, R. Inoue, Y. Nishino, A. Okuda, O. Matsumoto, T. Taga, F. Yamashita, Y. Takakura, M. Hashida F. Sakurai, R. Inoue, Y. Nishino, A. Okuda, O. Matsumoto, T. Taga, F. Yamashita, Y. Takakura, M. Hashida F. Sakurai, R. Inoue, Y. Nishino, A. Okuda, O. Matsumoto, T. Taga, F. Yamashita, Y. Takakura, M. Hashida Erratum: Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (Journal of Controlled Release 66 (2000) (255-269) PII: S0168365999002801) Erratum: Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (Journal of Controlled Release 66 (2000) (255-269) PII: S0168365999002801) Erratum: Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (Journal of Controlled Release 66 (2000) (255-269) PII: S0168365999002801) Journal of Controlled Release, 69, 1, 219-220 Journal of Controlled Release, 69, 1, 219-220 Journal of Controlled Release, 69, 1, 219-220 2000/10/03 Refereed English Research paper(scientific journal) Disclose to all
T Kageyama, M Nakamura, A Matsuo, Y Yamasaki, Y Takakura, M Hashida, Y Kanai, M Naito, T Tsuruo, N Minato, S Shimohama T Kageyama, M Nakamura, A Matsuo, Y Yamasaki, Y Takakura, M Hashida, Y Kanai, M Naito, T Tsuruo, N Minato, S Shimohama T Kageyama, M Nakamura, A Matsuo, Y Yamasaki, Y Takakura, M Hashida, Y Kanai, M Naito, T Tsuruo, N Minato, S Shimohama The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier BRAIN RESEARCH, 879, 1-2, 115-121 BRAIN RESEARCH, 879, 1-2, 115-121 BRAIN RESEARCH, 879, 1-2, 115-121 2000/10 Refereed English Research paper(scientific journal) Disclose to all
F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression JOURNAL OF CONTROLLED RELEASE, 66, 2-3, 255-269 JOURNAL OF CONTROLLED RELEASE, 66, 2-3, 255-269 JOURNAL OF CONTROLLED RELEASE, 66, 2-3, 255-269 2000/05 Refereed English Research paper(scientific journal) Disclose to all
S Nakajima, Y Koshino, T Nomura, F Yamashita, S Agrawal, Y Takakura, M Hashida S Nakajima, Y Koshino, T Nomura, F Yamashita, S Agrawal, Y Takakura, M Hashida S Nakajima, Y Koshino, T Nomura, F Yamashita, S Agrawal, Y Takakura, M Hashida Intratumoral pharmacokinetics of oligonucleotides in a tissue-isolated tumor perfusion system Intratumoral pharmacokinetics of oligonucleotides in a tissue-isolated tumor perfusion system Intratumoral pharmacokinetics of oligonucleotides in a tissue-isolated tumor perfusion system ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 10, 2, 105-110 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 10, 2, 105-110 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 10, 2, 105-110 2000/04 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, M Yamauchi, K Morimoto, E Ishida, Y Takakura, M Hashida M Nishikawa, M Yamauchi, K Morimoto, E Ishida, Y Takakura, M Hashida M Nishikawa, M Yamauchi, K Morimoto, E Ishida, Y Takakura, M Hashida Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system GENE THERAPY, 7, 7, 548-555 GENE THERAPY, 7, 7, 548-555 GENE THERAPY, 7, 7, 548-555 2000/04 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, K Akamatsu, M Nishikawa, F Yamashita, H Yoshikawa, Y Takakura M Hashida, K Akamatsu, M Nishikawa, F Yamashita, H Yoshikawa, Y Takakura M Hashida, K Akamatsu, M Nishikawa, F Yamashita, H Yoshikawa, Y Takakura Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting PHARMAZIE, 55, 3, 202-205 PHARMAZIE, 55, 3, 202-205 PHARMAZIE, 55, 3, 202-205 2000/03 Refereed English Research paper(scientific journal) Disclose to all
T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages JOURNAL OF DRUG TARGETING, 7, 5, 363-+ JOURNAL OF DRUG TARGETING, 7, 5, 363-+ JOURNAL OF DRUG TARGETING, 7, 5, 363-+ 2000 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, S Takemura, F Yamashita, Y Takakura, DKF Meijer, M Hashida, PJ Swart M Nishikawa, S Takemura, F Yamashita, Y Takakura, DKF Meijer, M Hashida, PJ Swart M Nishikawa, S Takemura, F Yamashita, Y Takakura, DKF Meijer, M Hashida, PJ Swart Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice JOURNAL OF DRUG TARGETING, 8, 1, 29-38 JOURNAL OF DRUG TARGETING, 8, 1, 29-38 JOURNAL OF DRUG TARGETING, 8, 1, 29-38 2000 Refereed English Research paper(scientific journal) Disclose to all
T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida T Takagi, M Hashiguchi, T Hiramatsu, F Yamashita, Y Takakura, M Hashida Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages JOURNAL OF DRUG TARGETING, 7, 5, 363-+ JOURNAL OF DRUG TARGETING, 7, 5, 363-+ JOURNAL OF DRUG TARGETING, 7, 5, 363-+ 2000 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, K Akamatsu, M Nishikawa, F Yamashita, Y Takakura M Hashida, K Akamatsu, M Nishikawa, F Yamashita, Y Takakura M Hashida, K Akamatsu, M Nishikawa, F Yamashita, Y Takakura Design of polymeric prodrugs of prostaglandin E-1 having galactose residue for hepatocyte targeting Design of polymeric prodrugs of prostaglandin E-1 having galactose residue for hepatocyte targeting Design of polymeric prodrugs of prostaglandin E-1 having galactose residue for hepatocyte targeting JOURNAL OF CONTROLLED RELEASE, 62, 1-2, 253-262 JOURNAL OF CONTROLLED RELEASE, 62, 1-2, 253-262 JOURNAL OF CONTROLLED RELEASE, 62, 1-2, 253-262 1999/11 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, T Kimura Interaction of polystyrene microspheres with liver cells: roles of membrane receptors and serum proteins Interaction of polystyrene microspheres with liver cells: roles of membrane receptors and serum proteins Interaction of polystyrene microspheres with liver cells: roles of membrane receptors and serum proteins BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1472, 1-2, 165-172 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1472, 1-2, 165-172 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1472, 1-2, 165-172 1999/10 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, M Yoshida, J Kubo, M Nishikawa, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, J Kubo, M Nishikawa, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, J Kubo, M Nishikawa, Y Takakura, M Hashida, K Higaki, T Kimura Mechanisms of hepatic disposition of polystyrene microspheres in rats: Effects of serum depend on the sizes of microspheres Mechanisms of hepatic disposition of polystyrene microspheres in rats: Effects of serum depend on the sizes of microspheres Mechanisms of hepatic disposition of polystyrene microspheres in rats: Effects of serum depend on the sizes of microspheres JOURNAL OF CONTROLLED RELEASE, 61, 3, 241-250 JOURNAL OF CONTROLLED RELEASE, 61, 3, 241-250 JOURNAL OF CONTROLLED RELEASE, 61, 3, 241-250 1999/09 Refereed English Research paper(scientific journal) Disclose to all
K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida Development of a hepatocyte-specific prostaglandin E-1 polymeric prodrug and its potential for preventing carbon tetrachloride-induced fulminant hepatitis in mice Development of a hepatocyte-specific prostaglandin E-1 polymeric prodrug and its potential for preventing carbon tetrachloride-induced fulminant hepatitis in mice Development of a hepatocyte-specific prostaglandin E-1 polymeric prodrug and its potential for preventing carbon tetrachloride-induced fulminant hepatitis in mice JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 290, 3, 1242-1249 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 290, 3, 1242-1249 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 290, 3, 1242-1249 1999/09 Refereed English Research paper(scientific journal) Disclose to all
F Staud, M Nishikawa, K Morimoto, Y Takakura, M Hashida F Staud, M Nishikawa, K Morimoto, Y Takakura, M Hashida F Staud, M Nishikawa, K Morimoto, Y Takakura, M Hashida Disposition of radioactivity after injection of liver-targeted proteins labeled with In-111 or I-125. Effect of labeling on distribution and excretion of radioactivity in rats Disposition of radioactivity after injection of liver-targeted proteins labeled with In-111 or I-125. Effect of labeling on distribution and excretion of radioactivity in rats Disposition of radioactivity after injection of liver-targeted proteins labeled with In-111 or I-125. Effect of labeling on distribution and excretion of radioactivity in rats JOURNAL OF PHARMACEUTICAL SCIENCES, 88, 6, 577-585 JOURNAL OF PHARMACEUTICAL SCIENCES, 88, 6, 577-585 JOURNAL OF PHARMACEUTICAL SCIENCES, 88, 6, 577-585 1999/06 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, M Yoshida, K Higaki, T Kimura, K Shiraishi, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Yoshida, K Higaki, T Kimura, K Shiraishi, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Yoshida, K Higaki, T Kimura, K Shiraishi, M Nishikawa, Y Takakura, M Hashida Hepatic uptake of polystyrene microspheres in rats: Effect of particle size on intrahepatic distribution Hepatic uptake of polystyrene microspheres in rats: Effect of particle size on intrahepatic distribution Hepatic uptake of polystyrene microspheres in rats: Effect of particle size on intrahepatic distribution JOURNAL OF CONTROLLED RELEASE, 59, 1, 15-22 JOURNAL OF CONTROLLED RELEASE, 59, 1, 15-22 JOURNAL OF CONTROLLED RELEASE, 59, 1, 15-22 1999/05 Refereed English Research paper(scientific journal) Disclose to all
Y Yabe, M Nishikawa, A Tamada, Y Takakura, M Hashida Y Yabe, M Nishikawa, A Tamada, Y Takakura, M Hashida Y Yabe, M Nishikawa, A Tamada, Y Takakura, M Hashida Targeted delivery and improved therapeutic potential of catalase by chemical modification: Combination with superoxide dismutase derivatives Targeted delivery and improved therapeutic potential of catalase by chemical modification: Combination with superoxide dismutase derivatives Targeted delivery and improved therapeutic potential of catalase by chemical modification: Combination with superoxide dismutase derivatives JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 289, 2, 1176-1184 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 289, 2, 1176-1184 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 289, 2, 1176-1184 1999/05 Refereed English Research paper(scientific journal) Disclose to all
F Staud, M Nishikawa, Y Takakura, M Hashida F Staud, M Nishikawa, Y Takakura, M Hashida F Staud, M Nishikawa, Y Takakura, M Hashida Liver uptake and hepato-biliary transfer of galactosylated proteins in rats are determined by the extent of galactosylation Liver uptake and hepato-biliary transfer of galactosylated proteins in rats are determined by the extent of galactosylation Liver uptake and hepato-biliary transfer of galactosylated proteins in rats are determined by the extent of galactosylation BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1427, 2, 183-192 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1427, 2, 183-192 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1427, 2, 183-192 1999/04 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, T Takagi, M Hashiguchi, M Nisihikawa, F Yamashita, T Doi, T Imanishi, H Suzuki, T Kodama, M Hashida Y Takakura, T Takagi, M Hashiguchi, M Nisihikawa, F Yamashita, T Doi, T Imanishi, H Suzuki, T Kodama, M Hashida Y Takakura, T Takagi, M Hashiguchi, M Nisihikawa, F Yamashita, T Doi, T Imanishi, H Suzuki, T Kodama, M Hashida Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class a scavenger receptor knockout mice Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class a scavenger receptor knockout mice Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class a scavenger receptor knockout mice PHARMACEUTICAL RESEARCH, 16, 4, 503-508 PHARMACEUTICAL RESEARCH, 16, 4, 503-508 PHARMACEUTICAL RESEARCH, 16, 4, 503-508 1999/04 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, M Nishikawa, F Yamashita, Y Takakura M Hashida, M Nishikawa, F Yamashita, Y Takakura M Hashida, M Nishikawa, F Yamashita, Y Takakura Cell specific targeting of drugs and genes with glycosylated liposomes. Cell specific targeting of drugs and genes with glycosylated liposomes. Cell specific targeting of drugs and genes with glycosylated liposomes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 217, 1, U559-U559 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 217, 1, U559-U559 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 217, 1, U559-U559 1999/03 Refereed English Disclose to all
H Masuda, Y Takakura, M Hashida H Masuda, Y Takakura, M Hashida H Masuda, Y Takakura, M Hashida Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1426, 3, 420-428 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1426, 3, 420-428 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1426, 3, 420-428 1999/02 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, F Staud, S Takemura, Y Takakura, M Hashida M Nishikawa, F Staud, S Takemura, Y Takakura, M Hashida M Nishikawa, F Staud, S Takemura, Y Takakura, M Hashida Pharmacokinetic evaluation of biodistribution data obtained with radiolabeled proteins in mice Pharmacokinetic evaluation of biodistribution data obtained with radiolabeled proteins in mice Pharmacokinetic evaluation of biodistribution data obtained with radiolabeled proteins in mice BIOLOGICAL & PHARMACEUTICAL BULLETIN, 22, 2, 214-218 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 22, 2, 214-218 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 22, 2, 214-218 1999/02 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Passive targeting with macromolecular drug carriers Passive targeting with macromolecular drug carriers Passive targeting with macromolecular drug carriers Drug Delivery System, 14, 6, 427-431 Drug Delivery System, 14, 6, 427-431 Drug Delivery System, 14, 6, 427-431 1999 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Yoshinobu Takakura, Kazuo Maruyama, Masayuki Yokoyama Passive targeting of drug Passive targeting of drug Passive targeting of drug Drug Delivery System, 14, 6, 425-426 Drug Delivery System, 14, 6, 425-426 Drug Delivery System, 14, 6, 425-426 1999 Refereed English Research paper(scientific journal) Disclose to all
S Okamoto, K Nakanishi, Y Watanabe, F Yamashita, Y Takakura, M Hashida S. Okamoto, K. Nakanishi, Y. Watanabe, F. Yamashita, Y. Takakura, M. Hashida S Okamoto, K Nakanishi, Y Watanabe, F Yamashita, Y Takakura, M Hashida Stimulation side-dependent asymmetrical secretion of poly I : poly C-induced interferon-beta from polarized epithelial cell lines Stimulation side-dependent asymmetrical secretion of poly I:poly C-induced interferon-β from polarized epithelial cell lines Stimulation side-dependent asymmetrical secretion of poly I : poly C-induced interferon-beta from polarized epithelial cell lines BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 254, 1, 5-9 Biochemical and Biophysical Research Communications, 254, 1, 5-9 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 254, 1, 5-9 1999/01 Refereed English Research paper(scientific journal) Disclose to all
H Yura, N Yoshimura, T Hamashima, K Akamatsu, M Nishikawa, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, K Akamatsu, M Nishikawa, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, K Akamatsu, M Nishikawa, Y Takakura, M Hashida Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate Synthesis and pharmacokinetics of a novel macromolecular prodrug of Tacrolimus (FK506), FK506-dextran conjugate JOURNAL OF CONTROLLED RELEASE, 57, 1, 87-99 JOURNAL OF CONTROLLED RELEASE, 57, 1, 87-99 JOURNAL OF CONTROLLED RELEASE, 57, 1, 87-99 1999/01 Refereed English Research paper(scientific journal) Disclose to all
T Nomura, K Yasuda, T Yamada, S Okamoto, RI Mahato, Y Watanabe, Y Takakura, M Hashida T. Nomura, K. Yasuda, T. Yamada, S. Okamoto, R.I. Mahato, Y. Watanabe, Y. Takakura, M. Hashida T Nomura, K Yasuda, T Yamada, S Okamoto, RI Mahato, Y Watanabe, Y Takakura, M Hashida Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice Gene expression and antitumor effects following direct interferon (IFN)-γ gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice GENE THERAPY, 6, 1, 121-129 Gene Therapy, 6, 1, 121-129 GENE THERAPY, 6, 1, 121-129 1999/01 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, M Yoshida, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura K Ogawara, M Yoshida, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura Uptake by hepatocytes and biliary excretion of intravenously administered polystyrene microspheres in rats Uptake by hepatocytes and biliary excretion of intravenously administered polystyrene microspheres in rats Uptake by hepatocytes and biliary excretion of intravenously administered polystyrene microspheres in rats JOURNAL OF DRUG TARGETING, 7, 3, 213-+ JOURNAL OF DRUG TARGETING, 7, 3, 213-+ JOURNAL OF DRUG TARGETING, 7, 3, 213-+ 1999 Refereed English Research paper(scientific journal) Disclose to all
KI Ogawara, S Hasegawa, M Nishikawa, Y Takakura, M Hashida KI Ogawara, S Hasegawa, M Nishikawa, Y Takakura, M Hashida KI Ogawara, S Hasegawa, M Nishikawa, Y Takakura, M Hashida Pharmacokinetic evaluation of mannosylated bovine serum albumin as a liver cell-specific carrier: Quantitative comparison with other hepatotropic ligands Pharmacokinetic evaluation of mannosylated bovine serum albumin as a liver cell-specific carrier: Quantitative comparison with other hepatotropic ligands Pharmacokinetic evaluation of mannosylated bovine serum albumin as a liver cell-specific carrier: Quantitative comparison with other hepatotropic ligands JOURNAL OF DRUG TARGETING, 6, 5, 349-360 JOURNAL OF DRUG TARGETING, 6, 5, 349-360 JOURNAL OF DRUG TARGETING, 6, 5, 349-360 1999 Refereed English Research paper(scientific journal) Disclose to all
Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Hepatocyte-specific distribution of catalase and its inhibitory effect on hepatic ischemia/reperfusion injury in mice Hepatocyte-specific distribution of catalase and its inhibitory effect on hepatic ischemia/reperfusion injury in mice Hepatocyte-specific distribution of catalase and its inhibitory effect on hepatic ischemia/reperfusion injury in mice FREE RADICAL RESEARCH, 30, 4, 265-274 FREE RADICAL RESEARCH, 30, 4, 265-274 FREE RADICAL RESEARCH, 30, 4, 265-274 1999 Refereed English Research paper(scientific journal) Disclose to all
A Takagi, Y Yabe, M Yoshida, Y Takakura, M Hashida A Takagi, Y Yabe, M Yoshida, Y Takakura, M Hashida A Takagi, Y Yabe, M Yoshida, Y Takakura, M Hashida Hepatic disposition characteristics of recombinant human interleukin-11 (rhIL-11) in the perfused rat liver Hepatic disposition characteristics of recombinant human interleukin-11 (rhIL-11) in the perfused rat liver Hepatic disposition characteristics of recombinant human interleukin-11 (rhIL-11) in the perfused rat liver BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 12, 1364-1366 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 12, 1364-1366 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 12, 1364-1366 1998/12 Refereed English Research paper(scientific journal) Disclose to all
S Kawakami, F Yamashita, M Nishikawa, Y Takakura, M Hashida S Kawakami, F Yamashita, M Nishikawa, Y Takakura, M Hashida S Kawakami, F Yamashita, M Nishikawa, Y Takakura, M Hashida Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 252, 1, 78-83 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 252, 1, 78-83 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 252, 1, 78-83 1998/11 Refereed English Research paper(scientific journal) Disclose to all
S Okamoto, Y Watanabe, Y Takakura, M Hashida S Okamoto, Y Watanabe, Y Takakura, M Hashida S Okamoto, Y Watanabe, Y Takakura, M Hashida Cationic liposome-mediated efficient induction of type I interferons by a low dose of poly I : poly C in mouse cell lines Cationic liposome-mediated efficient induction of type I interferons by a low dose of poly I : poly C in mouse cell lines Cationic liposome-mediated efficient induction of type I interferons by a low dose of poly I : poly C in mouse cell lines JOURNAL OF BIOCHEMISTRY, 124, 4, 697-701 JOURNAL OF BIOCHEMISTRY, 124, 4, 697-701 JOURNAL OF BIOCHEMISTRY, 124, 4, 697-701 1998/10 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, S Takemura, Y Takakura, M Hashida M Nishikawa, S Takemura, Y Takakura, M Hashida M Nishikawa, S Takemura, Y Takakura, M Hashida Targeted delivery of plasmid DNA to hepatocytes in vivo: Optimization of the pharmacokinetics of plasmid DNA galactosylated poly(L-lysine) complexes by controlling their physicochemical properties Targeted delivery of plasmid DNA to hepatocytes in vivo: Optimization of the pharmacokinetics of plasmid DNA galactosylated poly(L-lysine) complexes by controlling their physicochemical properties Targeted delivery of plasmid DNA to hepatocytes in vivo: Optimization of the pharmacokinetics of plasmid DNA galactosylated poly(L-lysine) complexes by controlling their physicochemical properties JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 287, 1, 408-415 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 287, 1, 408-415 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 287, 1, 408-415 1998/10 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, RI Mahato, M Hashida Y Takakura, RI Mahato, M Hashida Y Takakura, RI Mahato, M Hashida Extravasation of macromolecules Extravasation of macromolecules Extravasation of macromolecules ADVANCED DRUG DELIVERY REVIEWS, 34, 1, 93-108 ADVANCED DRUG DELIVERY REVIEWS, 34, 1, 93-108 ADVANCED DRUG DELIVERY REVIEWS, 34, 1, 93-108 1998/10 Refereed English Disclose to all
T Takino, N Koreeda, T Nomura, T Sakaeda, F Yamashita, Y Takakura, M Hashida T Takino, N Koreeda, T Nomura, T Sakaeda, F Yamashita, Y Takakura, M Hashida T Takino, N Koreeda, T Nomura, T Sakaeda, F Yamashita, Y Takakura, M Hashida Control of plasma cholesterol-lowering action of probucol with various lipid carrier systems Control of plasma cholesterol-lowering action of probucol with various lipid carrier systems Control of plasma cholesterol-lowering action of probucol with various lipid carrier systems BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 5, 492-497 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 5, 492-497 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 21, 5, 492-497 1998/05 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, S Takemura, M Nishikawa, Y Takakura M Hashida, S Takemura, M Nishikawa, Y Takakura M Hashida, S Takemura, M Nishikawa, Y Takakura Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine) Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine) Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine) JOURNAL OF CONTROLLED RELEASE, 53, 1-3, 301-310 JOURNAL OF CONTROLLED RELEASE, 53, 1-3, 301-310 JOURNAL OF CONTROLLED RELEASE, 53, 1-3, 301-310 1998/04 Refereed English Research paper(scientific journal) Disclose to all
T Takagi, M Hashiguchi, RI Mahato, H Tokuda, Y Takakura, M Hashida T Takagi, M Hashiguchi, RI Mahato, H Tokuda, Y Takakura, M Hashida T Takagi, M Hashiguchi, RI Mahato, H Tokuda, Y Takakura, M Hashida Involvement of specific mechanism in plasmid DNA uptake by mouse peritoneal macrophages Involvement of specific mechanism in plasmid DNA uptake by mouse peritoneal macrophages Involvement of specific mechanism in plasmid DNA uptake by mouse peritoneal macrophages BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 3, 729-733 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 3, 729-733 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 3, 729-733 1998/04 Refereed English Research paper(scientific journal) Disclose to all
M Nakamura, P Davila-Zavala, H Tokuda, Y Takakura, M Hashida M Nakamura, P Davila-Zavala, H Tokuda, Y Takakura, M Hashida M Nakamura, P Davila-Zavala, H Tokuda, Y Takakura, M Hashida Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 1, 235-239 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 1, 235-239 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 245, 1, 235-239 1998/04 Refereed English Research paper(scientific journal) Disclose to all
Takehiko Nomura, Akira Saikawa, Satoko Morita, Toshiyuki Sakaeda, Fumiyoshi Yamashita, Kazuo Honda, Yoshinobu Takakura, Mitsuru Hashida Takehiko Nomura, Akira Saikawa, Satoko Morita, Toshiyuki Sakaeda, Fumiyoshi Yamashita, Kazuo Honda, Yoshinobu Takakura, Mitsuru Hashida Takehiko Nomura, Akira Saikawa, Satoko Morita, Toshiyuki Sakaeda, Fumiyoshi Yamashita, Kazuo Honda, Yoshinobu Takakura, Mitsuru Hashida Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection Journal of Controlled Release, 52, 3, 239-252 Journal of Controlled Release, 52, 3, 239-252 Journal of Controlled Release, 52, 3, 239-252 1998/03/31 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, Y Oka, M Hashida Y Takakura, Y Oka, M Hashida Y Takakura, Y Oka, M Hashida Cellular uptake properties of oligonucleotides in LLC-PK1 renal epithelial cells Cellular uptake properties of oligonucleotides in LLC-PK1 renal epithelial cells Cellular uptake properties of oligonucleotides in LLC-PK1 renal epithelial cells ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 8, 1, 67-73 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 8, 1, 67-73 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 8, 1, 67-73 1998/02 Refereed English Research paper(scientific journal) Disclose to all
K Ogawara, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Nishikawa, Y Takakura, M Hashida Pharmacokinetic analysis of hepatic uptake of galactosylated bovine serum albumin in a perfused rat liver Pharmacokinetic analysis of hepatic uptake of galactosylated bovine serum albumin in a perfused rat liver Pharmacokinetic analysis of hepatic uptake of galactosylated bovine serum albumin in a perfused rat liver JOURNAL OF CONTROLLED RELEASE, 50, 1-3, 309-317 JOURNAL OF CONTROLLED RELEASE, 50, 1-3, 309-317 JOURNAL OF CONTROLLED RELEASE, 50, 1-3, 309-317 1998/01 Refereed English Research paper(scientific journal) Disclose to all
T Nomura, N Koreeda, F Yamashita, Y Takakura, M Hashida T Nomura, N Koreeda, F Yamashita, Y Takakura, M Hashida T Nomura, N Koreeda, F Yamashita, Y Takakura, M Hashida Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors PHARMACEUTICAL RESEARCH, 15, 1, 128-132 PHARMACEUTICAL RESEARCH, 15, 1, 128-132 PHARMACEUTICAL RESEARCH, 15, 1, 128-132 1998/01 Refereed English Research paper(scientific journal) Disclose to all
Y. Takakura Y. Takakura Y. Takakura Drug delivery systems in gene therapy Drug delivery systems in gene therapy Drug delivery systems in gene therapy Nippon rinsho. Japanese journal of clinical medicine, 56, 3, 691-695 Nippon rinsho. Japanese journal of clinical medicine, 56, 3, 691-695 Nippon rinsho. Japanese journal of clinical medicine, 56, 3, 691-695 1998 Refereed English Disclose to all
K Akamatsu, M Imai, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, M Imai, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida K Akamatsu, M Imai, Y Yamasaki, M Nishikawa, Y Takakura, M Hashida Disposition characteristics of glycosylated poly(amino acids) as liver cell-specific drug carrier Disposition characteristics of glycosylated poly(amino acids) as liver cell-specific drug carrier Disposition characteristics of glycosylated poly(amino acids) as liver cell-specific drug carrier JOURNAL OF DRUG TARGETING, 6, 3, 229-239 JOURNAL OF DRUG TARGETING, 6, 3, 229-239 JOURNAL OF DRUG TARGETING, 6, 3, 229-239 1998 Refereed English Research paper(scientific journal) Disclose to all
T Kanamaru, T Takagi, Y Takakura, M Hashida T Kanamaru, T Takagi, Y Takakura, M Hashida T Kanamaru, T Takagi, Y Takakura, M Hashida Biological effects and cellular uptake of c-myc antisense oligonucleotides and their cationic liposome complexes Biological effects and cellular uptake of c-myc antisense oligonucleotides and their cationic liposome complexes Biological effects and cellular uptake of c-myc antisense oligonucleotides and their cationic liposome complexes JOURNAL OF DRUG TARGETING, 5, 4, 235-+ JOURNAL OF DRUG TARGETING, 5, 4, 235-+ JOURNAL OF DRUG TARGETING, 5, 4, 235-+ 1998 Refereed English Research paper(scientific journal) Disclose to all
K Akamatsu, M Nishikawa, Y Takakura, M Hashida K Akamatsu, M Nishikawa, Y Takakura, M Hashida K Akamatsu, M Nishikawa, Y Takakura, M Hashida Synthesis and biodistribution study of liver-specific prostaglandin E-1 polymeric conjugate Synthesis and biodistribution study of liver-specific prostaglandin E-1 polymeric conjugate Synthesis and biodistribution study of liver-specific prostaglandin E-1 polymeric conjugate INTERNATIONAL JOURNAL OF PHARMACEUTICS, 155, 1, 65-74 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 155, 1, 65-74 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 155, 1, 65-74 1997/09 Refereed English Research paper(scientific journal) Disclose to all
T Nomura, S Nakajima, K Kawabata, F Yamashita, Y Takakura, M Hashida T Nomura, S Nakajima, K Kawabata, F Yamashita, Y Takakura, M Hashida T Nomura, S Nakajima, K Kawabata, F Yamashita, Y Takakura, M Hashida Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer CANCER RESEARCH, 57, 13, 2681-2686 CANCER RESEARCH, 57, 13, 2681-2686 CANCER RESEARCH, 57, 13, 2681-2686 1997/07 Refereed English Research paper(scientific journal) Disclose to all
H Bando, S Mohri, F Yamashita, Y Takakura, M HAshida H Bando, S Mohri, F Yamashita, Y Takakura, M HAshida H Bando, S Mohri, F Yamashita, Y Takakura, M HAshida Effects of skin metabolism on percutaneous penetration of lipophilic drugs Effects of skin metabolism on percutaneous penetration of lipophilic drugs Effects of skin metabolism on percutaneous penetration of lipophilic drugs JOURNAL OF PHARMACEUTICAL SCIENCES, 86, 6, 759-761 JOURNAL OF PHARMACEUTICAL SCIENCES, 86, 6, 759-761 JOURNAL OF PHARMACEUTICAL SCIENCES, 86, 6, 759-761 1997/06 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, H Hirabayashi, M Nishikawa, Y Takakura M Hashida, H Hirabayashi, M Nishikawa, Y Takakura M Hashida, H Hirabayashi, M Nishikawa, Y Takakura Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis JOURNAL OF CONTROLLED RELEASE, 46, 1-2, 129-137 JOURNAL OF CONTROLLED RELEASE, 46, 1-2, 129-137 JOURNAL OF CONTROLLED RELEASE, 46, 1-2, 129-137 1997/05 Refereed English Research paper(scientific journal) Disclose to all
H Furitsu, K Ogawara, T Fujita, F Yamashita, Y Takakura, H Sezaki, M Hashida H Furitsu, K Ogawara, T Fujita, F Yamashita, Y Takakura, H Sezaki, M Hashida H Furitsu, K Ogawara, T Fujita, F Yamashita, Y Takakura, H Sezaki, M Hashida Pharmacokinetic analysis of scavenger receptor-mediated uptake of anionized proteins in the isolated perfused rat liver Pharmacokinetic analysis of scavenger receptor-mediated uptake of anionized proteins in the isolated perfused rat liver Pharmacokinetic analysis of scavenger receptor-mediated uptake of anionized proteins in the isolated perfused rat liver INTERNATIONAL JOURNAL OF PHARMACEUTICS, 151, 1, 15-26 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 151, 1, 15-26 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 151, 1, 15-26 1997/05 Refereed English Research paper(scientific journal) Disclose to all
T Takagi, M Kitano, S Masuda, H Tokuda, Y Takakura, M Hashida T Takagi, M Kitano, S Masuda, H Tokuda, Y Takakura, M Hashida T Takagi, M Kitano, S Masuda, H Tokuda, Y Takakura, M Hashida Augmented inhibitory effect of superoxide dismutase on superoxide anion release from macrophages by direct cationization Augmented inhibitory effect of superoxide dismutase on superoxide anion release from macrophages by direct cationization Augmented inhibitory effect of superoxide dismutase on superoxide anion release from macrophages by direct cationization BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1335, 1-2, 91-98 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1335, 1-2, 91-98 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1335, 1-2, 91-98 1997/04 Refereed English Research paper(scientific journal) Disclose to all
K Kawabata, M Kondo, Y Watanabe, Y Takakura, M Hashida K. Kawabata, M. Kondo, Y. Watanabe, Y. Takakura, M. Hashida K Kawabata, M Kondo, Y Watanabe, Y Takakura, M Hashida Non-polarized secretion of mouse interferon-beta from gene-transferred human intestinal Caco-2 cells Non-polarized secretion of mouse interferon-β from gene-transferred human intestinal Caco-2 cells Non-polarized secretion of mouse interferon-beta from gene-transferred human intestinal Caco-2 cells PHARMACEUTICAL RESEARCH, 14, 4, 483-485 Pharmaceutical Research, 14, 4, 483-485 PHARMACEUTICAL RESEARCH, 14, 4, 483-485 1997/04 Refereed English Research paper(scientific journal) Disclose to all
RI Mahato, S Takemura, K Akamatsu, M Nishikawa, Y Takakura, M Hashida RI Mahato, S Takemura, K Akamatsu, M Nishikawa, Y Takakura, M Hashida RI Mahato, S Takemura, K Akamatsu, M Nishikawa, Y Takakura, M Hashida Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine) Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine) Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine) BIOCHEMICAL PHARMACOLOGY, 53, 6, 887-895 BIOCHEMICAL PHARMACOLOGY, 53, 6, 887-895 BIOCHEMICAL PHARMACOLOGY, 53, 6, 887-895 1997/03 Refereed English Research paper(scientific journal) Disclose to all
K Kawabata, S Okamoto, Y Takakura, M Hashida, T Hashimura, Y Watanabe K. Kawabata, S. Okamoto, Y. Takakura, M. Hashida, T. Hashimura, Y. Watanabe K Kawabata, S Okamoto, Y Takakura, M Hashida, T Hashimura, Y Watanabe A physiological role of interferon (IFN)-beta derived from tumor: Tumor growth of a mouse bladder carcinoma line MBT-2 is partially suppressed by autocrine IFN-beta A physiological role of interferon (IFN)-β derived from tumor: Tumor growth of a mouse bladder carcinoma line MBT-2 is partially suppressed by autocrine IFN-β A physiological role of interferon (IFN)-beta derived from tumor: Tumor growth of a mouse bladder carcinoma line MBT-2 is partially suppressed by autocrine IFN-beta CANCER LETTERS, 113, 1-2, 159-164 Cancer Letters, 113, 1-2, 159-164 CANCER LETTERS, 113, 1-2, 159-164 1997/02 Refereed English Research paper(scientific journal) Disclose to all
Noritaka Seko, Hiroto Bando, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Noritaka Seko, Hiroto Bando, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Noritaka Seko, Hiroto Bando, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Estimation of drug concentration profiles in skin based on a skin diffusion model Estimation of drug concentration profiles in skin based on a skin diffusion model Estimation of drug concentration profiles in skin based on a skin diffusion model Drug Delivery System, 12, 5, 359-365 Drug Delivery System, 12, 5, 359-365 Drug Delivery System, 12, 5, 359-365 1997 Refereed English Research paper(scientific journal) Disclose to all
H. Tokuda, H. Nagano, Y. Takakura, M. Hashida H. Tokuda, H. Nagano, Y. Takakura, M. Hashida H. Tokuda, H. Nagano, Y. Takakura, M. Hashida Uptake characteristics of anionized and cationized proteins in brain microvessel endothelial cells Uptake characteristics of anionized and cationized proteins in brain microvessel endothelial cells Uptake characteristics of anionized and cationized proteins in brain microvessel endothelial cells Pharmaceutical Sciences, 3, 3, 147-151 Pharmaceutical Sciences, 3, 3, 147-151 Pharmaceutical Sciences, 3, 3, 147-151 1997 Refereed English Disclose to all
RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations Nonviral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 14, 2, 133-172 CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 14, 2, 133-172 CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 14, 2, 133-172 1997 Refereed English Disclose to all
T. Nomura, Y. Takakura, M. Hashida T. Nomura, Y. Takakura, M. Hashida T. Nomura, Y. Takakura, M. Hashida Cancer gene therapy by direct intratumoral injection: Gene expression and intratumoral pharmacokinetics of plasmid dna Cancer gene therapy by direct intratumoral injection: Gene expression and intratumoral pharmacokinetics of plasmid dna Cancer gene therapy by direct intratumoral injection: Gene expression and intratumoral pharmacokinetics of plasmid dna Japanese Journal of Cancer and Chemotherapy, 24, 4, 483-488 Japanese Journal of Cancer and Chemotherapy, 24, 4, 483-488 Japanese Journal of Cancer and Chemotherapy, 24, 4, 483-488 1997 Refereed Japanese Research paper(international conference proceedings) Disclose to all
A Takagi, Y Yabe, Y Oka, K Sawai, Y Takakura, M Hashida A Takagi, Y Yabe, Y Oka, K Sawai, Y Takakura, M Hashida A Takagi, Y Yabe, Y Oka, K Sawai, Y Takakura, M Hashida Renal disposition of recombinant human interleukin-11 in the isolated perfused rat kidney Renal disposition of recombinant human interleukin-11 in the isolated perfused rat kidney Renal disposition of recombinant human interleukin-11 in the isolated perfused rat kidney PHARMACEUTICAL RESEARCH, 14, 1, 86-90 PHARMACEUTICAL RESEARCH, 14, 1, 86-90 PHARMACEUTICAL RESEARCH, 14, 1, 86-90 1997/01 Refereed English Research paper(scientific journal) Disclose to all
H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida In vivo evaluation of acyclovir prodrug penetration and metabolism through rat skin using a diffusion/bioconversion model In vivo evaluation of acyclovir prodrug penetration and metabolism through rat skin using a diffusion/bioconversion model In vivo evaluation of acyclovir prodrug penetration and metabolism through rat skin using a diffusion/bioconversion model PHARMACEUTICAL RESEARCH, 14, 1, 56-62 PHARMACEUTICAL RESEARCH, 14, 1, 56-62 PHARMACEUTICAL RESEARCH, 14, 1, 56-62 1997/01 Refereed English Research paper(scientific journal) Disclose to all
RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida Development of targeted delivery systems for nucleic acid drugs Development of targeted delivery systems for nucleic acid drugs Development of targeted delivery systems for nucleic acid drugs JOURNAL OF DRUG TARGETING, 4, 6, 337-357 JOURNAL OF DRUG TARGETING, 4, 6, 337-357 JOURNAL OF DRUG TARGETING, 4, 6, 337-357 1997 Refereed English Disclose to all
H Bando, M Sahashi, S Mohri, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, S Mohri, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, S Mohri, F Yamashita, Y Takakura, M Hashida In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination INTERNATIONAL JOURNAL OF PHARMACEUTICS, 145, 1-2, 103-113 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 145, 1-2, 103-113 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 145, 1-2, 103-113 1996/12 Refereed English Research paper(scientific journal) Disclose to all
K Sawai, RI Mahato, Y Oka, Y Takakura, M Hashida K Sawai, RI Mahato, Y Oka, Y Takakura, M Hashida K Sawai, RI Mahato, Y Oka, Y Takakura, M Hashida Disposition of oligonucleotides in isolated perfused rat kidney: Involvement of scavenger receptors in their renal uptake Disposition of oligonucleotides in isolated perfused rat kidney: Involvement of scavenger receptors in their renal uptake Disposition of oligonucleotides in isolated perfused rat kidney: Involvement of scavenger receptors in their renal uptake JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 279, 1, 284-290 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 279, 1, 284-290 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 279, 1, 284-290 1996/10 Refereed English Research paper(scientific journal) Disclose to all
A Saikawa, T Nomura, F Yamashita, Y Takakura, H Sezaki, M Hashida A Saikawa, T Nomura, F Yamashita, Y Takakura, H Sezaki, M Hashida A Saikawa, T Nomura, F Yamashita, Y Takakura, H Sezaki, M Hashida Pharmacokinetic analysis of drug disposition after intratumoral injection in a tissue-isolated tumor perfusion system Pharmacokinetic analysis of drug disposition after intratumoral injection in a tissue-isolated tumor perfusion system Pharmacokinetic analysis of drug disposition after intratumoral injection in a tissue-isolated tumor perfusion system PHARMACEUTICAL RESEARCH, 13, 10, 1438-1444 PHARMACEUTICAL RESEARCH, 13, 10, 1438-1444 PHARMACEUTICAL RESEARCH, 13, 10, 1438-1444 1996/10 Refereed English Research paper(scientific journal) Disclose to all
M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida Pharmacokinetic evaluation of polymeric carriers Pharmacokinetic evaluation of polymeric carriers Pharmacokinetic evaluation of polymeric carriers ADVANCED DRUG DELIVERY REVIEWS, 21, 2, 135-155 ADVANCED DRUG DELIVERY REVIEWS, 21, 2, 135-155 ADVANCED DRUG DELIVERY REVIEWS, 21, 2, 135-155 1996/09 Refereed English Disclose to all
M Hashida, RI Mahato, K Kawabata, T Miyao, M Nishikawa, Y Takakura M Hashida, RI Mahato, K Kawabata, T Miyao, M Nishikawa, Y Takakura M Hashida, RI Mahato, K Kawabata, T Miyao, M Nishikawa, Y Takakura Pharmacokinetics and targeted delivery of proteins and genes Pharmacokinetics and targeted delivery of proteins and genes Pharmacokinetics and targeted delivery of proteins and genes JOURNAL OF CONTROLLED RELEASE, 41, 1-2, 91-97 JOURNAL OF CONTROLLED RELEASE, 41, 1-2, 91-97 JOURNAL OF CONTROLLED RELEASE, 41, 1-2, 91-97 1996/08 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, M Hashida Y Takakura, M Hashida Y Takakura, M Hashida Delivery of plasmid DNA to endothelial cells Delivery of plasmid DNA to endothelial cells Delivery of plasmid DNA to endothelial cells EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 42, 4, 269-276 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 42, 4, 269-276 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 42, 4, 269-276 1996/08 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura Y Takakura Y Takakura Development of drug delivery systems for macromolecular drugs Development of drug delivery systems for macromolecular drugs Development of drug delivery systems for macromolecular drugs YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 116, 7, 519-532 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 116, 7, 519-532 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 116, 7, 519-532 1996/07 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, RI Mahato, M Nishikawa, M Hashida Y Takakura, RI Mahato, M Nishikawa, M Hashida Y Takakura, RI Mahato, M Nishikawa, M Hashida Control of pharmacokinetic profiles of drug-macromolecule conjugates Control of pharmacokinetic profiles of drug-macromolecule conjugates Control of pharmacokinetic profiles of drug-macromolecule conjugates ADVANCED DRUG DELIVERY REVIEWS, 19, 3, 377-399 ADVANCED DRUG DELIVERY REVIEWS, 19, 3, 377-399 ADVANCED DRUG DELIVERY REVIEWS, 19, 3, 377-399 1996/06 Refereed English Disclose to all
H Hirabayashi, M Nishikawa, Y Takakura, M Hashida H Hirabayashi, M Nishikawa, Y Takakura, M Hashida H Hirabayashi, M Nishikawa, Y Takakura, M Hashida Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery PHARMACEUTICAL RESEARCH, 13, 6, 880-884 PHARMACEUTICAL RESEARCH, 13, 6, 880-884 PHARMACEUTICAL RESEARCH, 13, 6, 880-884 1996/06 Refereed English Research paper(scientific journal) Disclose to all
H Bando, M Sahashi, T Takagi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, T Takagi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, T Takagi, F Yamashita, Y Takakura, M Hashida Analysis of in vitro skin penetration of acyclovir prodrugs based on a diffusion model with a metabolic process Analysis of in vitro skin penetration of acyclovir prodrugs based on a diffusion model with a metabolic process Analysis of in vitro skin penetration of acyclovir prodrugs based on a diffusion model with a metabolic process INTERNATIONAL JOURNAL OF PHARMACEUTICS, 135, 1-2, 91-102 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 135, 1-2, 91-102 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 135, 1-2, 91-102 1996/06 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, M Hashida Y Takakura, M Hashida Y Takakura, M Hashida Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution PHARMACEUTICAL RESEARCH, 13, 6, 820-831 PHARMACEUTICAL RESEARCH, 13, 6, 820-831 PHARMACEUTICAL RESEARCH, 13, 6, 820-831 1996/06 Refereed English Disclose to all
M Yoshida, RI Mahato, K Kawabata, Y Takakura, M Hashida M Yoshida, RI Mahato, K Kawabata, Y Takakura, M Hashida M Yoshida, RI Mahato, K Kawabata, Y Takakura, M Hashida Disposition characteristics of plasmid DNA in the single-pass rat liver perfusion system Disposition characteristics of plasmid DNA in the single-pass rat liver perfusion system Disposition characteristics of plasmid DNA in the single-pass rat liver perfusion system PHARMACEUTICAL RESEARCH, 13, 4, 599-603 PHARMACEUTICAL RESEARCH, 13, 4, 599-603 PHARMACEUTICAL RESEARCH, 13, 4, 599-603 1996/04 Refereed English Research paper(scientific journal) Disclose to all
H Bando, T Takagi, F Yamashita, Y Takakura, M Hashida H Bando, T Takagi, F Yamashita, Y Takakura, M Hashida H Bando, T Takagi, F Yamashita, Y Takakura, M Hashida Theoretical design of prodrug-enhancer combination based on a skin diffusion model: Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one Theoretical design of prodrug-enhancer combination based on a skin diffusion model: Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one Theoretical design of prodrug-enhancer combination based on a skin diffusion model: Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one PHARMACEUTICAL RESEARCH, 13, 3, 427-432 PHARMACEUTICAL RESEARCH, 13, 3, 427-432 PHARMACEUTICAL RESEARCH, 13, 3, 427-432 1996/03 Refereed English Research paper(scientific journal) Disclose to all
M Hashida, M Nishikawa, Y Takakura M Hashida, M Nishikawa, Y Takakura M Hashida, M Nishikawa, Y Takakura Receptor-mediated cell specific delivery of drugs to the liver and kidney Receptor-mediated cell specific delivery of drugs to the liver and kidney Receptor-mediated cell specific delivery of drugs to the liver and kidney ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 86-90 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 86-90 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 86-90 1996 Refereed English Research paper(international conference proceedings) Disclose to all
H Bando, F Yamashita, Y Takakura, M Hashida H Bando, F Yamashita, Y Takakura, M Hashida H Bando, F Yamashita, Y Takakura, M Hashida Theoretical design of skin penetration enhancement via prodrug-enhancer combination based on a diffusion model Theoretical design of skin penetration enhancement via prodrug-enhancer combination based on a diffusion model Theoretical design of skin penetration enhancement via prodrug-enhancer combination based on a diffusion model ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 363-364 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 363-364 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 363-364 1996 Refereed English Research paper(international conference proceedings) Disclose to all
Y Takakura, RI Mahato, T Nomura, K Sawai, M Yoshida, T Kanamaru, M Hashida Y Takakura, RI Mahato, T Nomura, K Sawai, M Yoshida, T Kanamaru, M Hashida Y Takakura, RI Mahato, T Nomura, K Sawai, M Yoshida, T Kanamaru, M Hashida Development of delivery systems for antisense oligonucleotides Development of delivery systems for antisense oligonucleotides Development of delivery systems for antisense oligonucleotides ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 357-358 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 357-358 ADVANCED BIOMATERIALS IN BIOMEDICAL ENGINEERING AND DRUG DELIVERY SYSTEMS, 357-358 1996 Refereed English Research paper(international conference proceedings) Disclose to all
PU Jani, T Nomura, F Yamashita, Y Takakura, AT Florence, M Hashida PU Jani, T Nomura, F Yamashita, Y Takakura, AT Florence, M Hashida PU Jani, T Nomura, F Yamashita, Y Takakura, AT Florence, M Hashida Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats JOURNAL OF DRUG TARGETING, 4, 2, 87-+ JOURNAL OF DRUG TARGETING, 4, 2, 87-+ JOURNAL OF DRUG TARGETING, 4, 2, 87-+ 1996 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Ram I. Mahato, Mitsunobu Yoshida, Taro Kanamaru, Mitsuru Hashida Yoshinobu Takakura, Ram I. Mahato, Mitsunobu Yoshida, Taro Kanamaru, Mitsuru Hashida Yoshinobu Takakura, Ram I. Mahato, Mitsunobu Yoshida, Taro Kanamaru, Mitsuru Hashida Uptake characteristics of oligonucleotides in the isolated rat liver perfusion system Uptake characteristics of oligonucleotides in the isolated rat liver perfusion system Uptake characteristics of oligonucleotides in the isolated rat liver perfusion system Antisense and Nucleic Acid Drug Development, 6, 3, 177-183 Antisense and Nucleic Acid Drug Development, 6, 3, 177-183 Antisense and Nucleic Acid Drug Development, 6, 3, 177-183 1996 Refereed English Research paper(scientific journal) Disclose to all
F Yamashita, H Bando, Y Takakura, M Hashida F Yamashita, H Bando, Y Takakura, M Hashida F Yamashita, H Bando, Y Takakura, M Hashida A deconvolution method for estimating the first-pass metabolism of orally administered drugs A deconvolution method for estimating the first-pass metabolism of orally administered drugs A deconvolution method for estimating the first-pass metabolism of orally administered drugs BIOLOGICAL & PHARMACEUTICAL BULLETIN, 18, 12, 1787-1789 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 18, 12, 1787-1789 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 18, 12, 1787-1789 1995/12 Refereed English Research paper(scientific journal) Disclose to all
Y Takakura, T Morita, M Fujikawa, M Hayashi, H Sezaki, M Hashida, RT Borchardt Y Takakura, T Morita, M Fujikawa, M Hayashi, H Sezaki, M Hashida, RT Borchardt Y Takakura, T Morita, M Fujikawa, M Hayashi, H Sezaki, M Hashida, RT Borchardt Characterization of LLC-PK1 kidney epithelial cells as an in vitro model for studying renal tubular reabsorption of protein drugs Characterization of LLC-PK1 kidney epithelial cells as an in vitro model for studying renal tubular reabsorption of protein drugs Characterization of LLC-PK1 kidney epithelial cells as an in vitro model for studying renal tubular reabsorption of protein drugs PHARMACEUTICAL RESEARCH, 12, 12, 1968-1972 PHARMACEUTICAL RESEARCH, 12, 12, 1968-1972 PHARMACEUTICAL RESEARCH, 12, 12, 1968-1972 1995/12 Refereed English Research paper(scientific journal) Disclose to all
A TAKAGI, H MASUDA, Y TAKAKURA, M HASHIDA A TAKAGI, H MASUDA, Y TAKAKURA, M HASHIDA A TAKAGI, H MASUDA, Y TAKAKURA, M HASHIDA DISPOSITION CHARACTERISTICS OF RECOMBINANT HUMAN INTERLEUKIN-11 AFTER A BOLUS INTRAVENOUS ADMINISTRATION IN MICE DISPOSITION CHARACTERISTICS OF RECOMBINANT HUMAN INTERLEUKIN-11 AFTER A BOLUS INTRAVENOUS ADMINISTRATION IN MICE DISPOSITION CHARACTERISTICS OF RECOMBINANT HUMAN INTERLEUKIN-11 AFTER A BOLUS INTRAVENOUS ADMINISTRATION IN MICE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 275, 2, 537-543 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 275, 2, 537-543 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 275, 2, 537-543 1995/11 Refereed English Research paper(scientific journal) Disclose to all
RI MAHATO, K KAWABATA, T NOMURA, Y TAKAKURA, M HASHIDA RI MAHATO, K KAWABATA, T NOMURA, Y TAKAKURA, M HASHIDA RI MAHATO, K KAWABATA, T NOMURA, Y TAKAKURA, M HASHIDA PHYSICOCHEMICAL AND PHARMACOKINETIC CHARACTERISTICS OF PLASMID DNA CATIONIC LIPOSOME COMPLEXES PHYSICOCHEMICAL AND PHARMACOKINETIC CHARACTERISTICS OF PLASMID DNA CATIONIC LIPOSOME COMPLEXES PHYSICOCHEMICAL AND PHARMACOKINETIC CHARACTERISTICS OF PLASMID DNA CATIONIC LIPOSOME COMPLEXES JOURNAL OF PHARMACEUTICAL SCIENCES, 84, 11, 1267-1271 JOURNAL OF PHARMACEUTICAL SCIENCES, 84, 11, 1267-1271 JOURNAL OF PHARMACEUTICAL SCIENCES, 84, 11, 1267-1271 1995/11 Refereed English Research paper(scientific journal) Disclose to all
M HASHIDA, M NISHIKAWA, Y TAKAKURA M HASHIDA, M NISHIKAWA, Y TAKAKURA M HASHIDA, M NISHIKAWA, Y TAKAKURA HEPATIC TARGETING OF DRUGS AND PROTEINS BY CHEMICAL MODIFICATION HEPATIC TARGETING OF DRUGS AND PROTEINS BY CHEMICAL MODIFICATION HEPATIC TARGETING OF DRUGS AND PROTEINS BY CHEMICAL MODIFICATION JOURNAL OF CONTROLLED RELEASE, 36, 1-2, 99-107 JOURNAL OF CONTROLLED RELEASE, 36, 1-2, 99-107 JOURNAL OF CONTROLLED RELEASE, 36, 1-2, 99-107 1995/09 Refereed English Research paper(scientific journal) Disclose to all
K KAWABATA, Y TAKAKURA, M HASHIDA K KAWABATA, Y TAKAKURA, M HASHIDA K KAWABATA, Y TAKAKURA, M HASHIDA THE FATE OF PLASMID DNA AFTER INTRAVENOUS-INJECTION IN MICE - INVOLVEMENT OF SCAVENGER RECEPTORS IN ITS HEPATIC-UPTAKE THE FATE OF PLASMID DNA AFTER INTRAVENOUS-INJECTION IN MICE - INVOLVEMENT OF SCAVENGER RECEPTORS IN ITS HEPATIC-UPTAKE THE FATE OF PLASMID DNA AFTER INTRAVENOUS-INJECTION IN MICE - INVOLVEMENT OF SCAVENGER RECEPTORS IN ITS HEPATIC-UPTAKE PHARMACEUTICAL RESEARCH, 12, 6, 825-830 PHARMACEUTICAL RESEARCH, 12, 6, 825-830 PHARMACEUTICAL RESEARCH, 12, 6, 825-830 1995/06 Refereed English Research paper(scientific journal) Disclose to all
S CHOKSAKULNIMITR, S MASUDA, H TOKUDA, Y TAKAKURA, M HASHIDA S CHOKSAKULNIMITR, S MASUDA, H TOKUDA, Y TAKAKURA, M HASHIDA S CHOKSAKULNIMITR, S MASUDA, H TOKUDA, Y TAKAKURA, M HASHIDA IN-VITRO CYTOTOXICITY OF MACROMOLECULES IN DIFFERENT CELL-CULTURE SYSTEMS IN-VITRO CYTOTOXICITY OF MACROMOLECULES IN DIFFERENT CELL-CULTURE SYSTEMS IN-VITRO CYTOTOXICITY OF MACROMOLECULES IN DIFFERENT CELL-CULTURE SYSTEMS JOURNAL OF CONTROLLED RELEASE, 34, 3, 233-241 JOURNAL OF CONTROLLED RELEASE, 34, 3, 233-241 JOURNAL OF CONTROLLED RELEASE, 34, 3, 233-241 1995/06 Refereed English Research paper(scientific journal) Disclose to all
M NISHIKAWA, C MIYAZAKI, F YAMASHITA, Y TAKAKURA, M HASHIDA M NISHIKAWA, C MIYAZAKI, F YAMASHITA, Y TAKAKURA, M HASHIDA M NISHIKAWA, C MIYAZAKI, F YAMASHITA, Y TAKAKURA, M HASHIDA GALACTOSYLATED PROTEINS ARE RECOGNIZED BY THE LIVER ACCORDING TO THE SURFACE-DENSITY OF GALACTOSE MOIETIES GALACTOSYLATED PROTEINS ARE RECOGNIZED BY THE LIVER ACCORDING TO THE SURFACE-DENSITY OF GALACTOSE MOIETIES GALACTOSYLATED PROTEINS ARE RECOGNIZED BY THE LIVER ACCORDING TO THE SURFACE-DENSITY OF GALACTOSE MOIETIES AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 268, 5, G849-G856 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 268, 5, G849-G856 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 268, 5, G849-G856 1995/05 Refereed English Research paper(scientific journal) Disclose to all
F YAMASHITA, Y KOYAMA, M KITANO, Y TAKAKURA, M HASHIDA F YAMASHITA, Y KOYAMA, M KITANO, Y TAKAKURA, M HASHIDA F YAMASHITA, Y KOYAMA, M KITANO, Y TAKAKURA, M HASHIDA ANALYSIS OF IN-VIVO SKIN PENETRATION ENHANCEMENT BY OLEIC-ACID BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM ANALYSIS OF IN-VIVO SKIN PENETRATION ENHANCEMENT BY OLEIC-ACID BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM ANALYSIS OF IN-VIVO SKIN PENETRATION ENHANCEMENT BY OLEIC-ACID BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM INTERNATIONAL JOURNAL OF PHARMACEUTICS, 117, 2, 173-179 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 117, 2, 173-179 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 117, 2, 173-179 1995/04 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, M HASHIDA Y TAKAKURA, M HASHIDA Y TAKAKURA, M HASHIDA MACROMOLECULAR DRUG CARRIER SYSTEMS IN CANCER-CHEMOTHERAPY - MACROMOLECULAR PRODRUGS MACROMOLECULAR DRUG CARRIER SYSTEMS IN CANCER-CHEMOTHERAPY - MACROMOLECULAR PRODRUGS MACROMOLECULAR DRUG CARRIER SYSTEMS IN CANCER-CHEMOTHERAPY - MACROMOLECULAR PRODRUGS CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, 18, 3, 207-231 CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, 18, 3, 207-231 CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, 18, 3, 207-231 1995/03 Refereed English Disclose to all
M NISHIKAWA, H HIRABAYASHI, Y TAKAKURA, M HASHIDA M NISHIKAWA, H HIRABAYASHI, Y TAKAKURA, M HASHIDA M NISHIKAWA, H HIRABAYASHI, Y TAKAKURA, M HASHIDA DESIGN FOR CELL-SPECIFIC TARGETING OF PROTEINS UTILIZING SUGAR-RECOGNITION MECHANISM - EFFECT OF MOLECULAR-WEIGHT OF PROTEINS ON TARGETING EFFICIENCY DESIGN FOR CELL-SPECIFIC TARGETING OF PROTEINS UTILIZING SUGAR-RECOGNITION MECHANISM - EFFECT OF MOLECULAR-WEIGHT OF PROTEINS ON TARGETING EFFICIENCY DESIGN FOR CELL-SPECIFIC TARGETING OF PROTEINS UTILIZING SUGAR-RECOGNITION MECHANISM - EFFECT OF MOLECULAR-WEIGHT OF PROTEINS ON TARGETING EFFICIENCY PHARMACEUTICAL RESEARCH, 12, 2, 209-214 PHARMACEUTICAL RESEARCH, 12, 2, 209-214 PHARMACEUTICAL RESEARCH, 12, 2, 209-214 1995/02 Refereed English Research paper(scientific journal) Disclose to all
Toichi Takino, Noriko Koreeda, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Toichi Takino, Noriko Koreeda, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Toichi Takino, Noriko Koreeda, Fumiyoshi Yamashita, Yoshinobu Takakura, Mitsuru Hashida Biodistribution control of lipophilic drugs with lipid carrier system Biodistribution control of lipophilic drugs with lipid carrier system Biodistribution control of lipophilic drugs with lipid carrier system Drug Delivery System, 10, 3, 153-158 Drug Delivery System, 10, 3, 153-158 Drug Delivery System, 10, 3, 153-158 1995 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Mitsuru Hashida Yoshinobu Takakura, Mitsuru Hashida Yoshinobu Takakura, Mitsuru Hashida Development of delivery systems of DNA medicines and possible obstacles to be overcome Development of delivery systems of DNA medicines and possible obstacles to be overcome Development of delivery systems of DNA medicines and possible obstacles to be overcome Drug Delivery System, 10, 6, 391-398 Drug Delivery System, 10, 6, 391-398 Drug Delivery System, 10, 6, 391-398 1995 Refereed English Research paper(scientific journal) Disclose to all
Kenzo Sawai, Takenori Miyao, Yoshinobu Takakura, Mitsuru Hashida Kenzo Sawai, Takenori Miyao, Yoshinobu Takakura, Mitsuru Hashida Kenzo Sawai, Takenori Miyao, Yoshinobu Takakura, Mitsuru Hashida Renal Disposition Characteristics of Oligonucleotides Modified at Terminal Linkages in the Perfused Rat Kidney Renal Disposition Characteristics of Oligonucleotides Modified at Terminal Linkages in the Perfused Rat Kidney Renal Disposition Characteristics of Oligonucleotides Modified at Terminal Linkages in the Perfused Rat Kidney Antisense Research and Development, 5, 4, 279-287 Antisense Research and Development, 5, 4, 279-287 Antisense Research and Development, 5, 4, 279-287 1995 Refereed English Research paper(scientific journal) Disclose to all
TAKUYA FUJITA, YOSHINOBU TAKAKURA, HITOSHI SEZAKI, MITSURU HASHIDA TAKUYA FUJITA, YOSHINOBU TAKAKURA, HITOSHI SEZAKI, MITSURU HASHIDA TAKUYA FUJITA, YOSHINOBU TAKAKURA, HITOSHI SEZAKI, MITSURU HASHIDA Control of Disposition Characteristics of Proteins by Direct Cationization in Mice Control of Disposition Characteristics of Proteins by Direct Cationization in Mice Control of Disposition Characteristics of Proteins by Direct Cationization in Mice Pharmacy and Pharmacology Communications, 1, 8, 371-375 Pharmacy and Pharmacology Communications, 1, 8, 371-375 Pharmacy and Pharmacology Communications, 1, 8, 371-375 1995 English Research paper(scientific journal) Disclose to all
RI MAHATO, K KAWABATA, Y TAKAKURA, M HASHIDA RI MAHATO, K KAWABATA, Y TAKAKURA, M HASHIDA RI MAHATO, K KAWABATA, Y TAKAKURA, M HASHIDA IN-VIVO DISPOSITION CHARACTERISTICS OF PLASMID DNA COMPLEXED WITH CATIONIC LIPOSOMES IN-VIVO DISPOSITION CHARACTERISTICS OF PLASMID DNA COMPLEXED WITH CATIONIC LIPOSOMES IN-VIVO DISPOSITION CHARACTERISTICS OF PLASMID DNA COMPLEXED WITH CATIONIC LIPOSOMES JOURNAL OF DRUG TARGETING, 3, 2, 149-157 JOURNAL OF DRUG TARGETING, 3, 2, 149-157 JOURNAL OF DRUG TARGETING, 3, 2, 149-157 1995 Refereed English Research paper(scientific journal) Disclose to all
T TAKINO, E NAGAHAMA, T SAKAEDA, F YAMASHITA, Y TAKAKURA, M HASHIDA T TAKINO, E NAGAHAMA, T SAKAEDA, F YAMASHITA, Y TAKAKURA, M HASHIDA T TAKINO, E NAGAHAMA, T SAKAEDA, F YAMASHITA, Y TAKAKURA, M HASHIDA PHARMACOKINETIC DISPOSITION ANALYSIS OF LIPOPHILIC DRUGS INJECTED WITH VARIOUS LIPID CARRIERS IN THE SINGLE-PASS RAT-LIVER PERFUSION SYSTEM PHARMACOKINETIC DISPOSITION ANALYSIS OF LIPOPHILIC DRUGS INJECTED WITH VARIOUS LIPID CARRIERS IN THE SINGLE-PASS RAT-LIVER PERFUSION SYSTEM PHARMACOKINETIC DISPOSITION ANALYSIS OF LIPOPHILIC DRUGS INJECTED WITH VARIOUS LIPID CARRIERS IN THE SINGLE-PASS RAT-LIVER PERFUSION SYSTEM INTERNATIONAL JOURNAL OF PHARMACEUTICS, 114, 1, 43-54 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 114, 1, 43-54 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 114, 1, 43-54 1995/01 Refereed English Research paper(scientific journal) Disclose to all
Takenori Miyao, Yoshinobu Takakura, Taishin Akiyama, Fumio Yoneda, Hitoshi Sezaki, Mitsuru Hashida Takenori Miyao, Yoshinobu Takakura, Taishin Akiyama, Fumio Yoneda, Hitoshi Sezaki, Mitsuru Hashida Takenori Miyao, Yoshinobu Takakura, Taishin Akiyama, Fumio Yoneda, Hitoshi Sezaki, Mitsuru Hashida Stability and Pharmacokinetic Characteristics of Oligonucleotides Modified at Terminal Linkages in Mice Stability and Pharmacokinetic Characteristics of Oligonucleotides Modified at Terminal Linkages in Mice Stability and Pharmacokinetic Characteristics of Oligonucleotides Modified at Terminal Linkages in Mice Antisense Research and Development, 5, 2, 115-121 Antisense Research and Development, 5, 2, 115-121 Antisense Research and Development, 5, 2, 115-121 1995 Refereed English Research paper(scientific journal) Disclose to all
M HASHIDA, Y TAKAKURA M HASHIDA, Y TAKAKURA M HASHIDA, Y TAKAKURA PHARMACOKINETICS IN DESIGN OF POLYMERIC DRUG-DELIVERY SYSTEMS PHARMACOKINETICS IN DESIGN OF POLYMERIC DRUG-DELIVERY SYSTEMS PHARMACOKINETICS IN DESIGN OF POLYMERIC DRUG-DELIVERY SYSTEMS JOURNAL OF CONTROLLED RELEASE, 31, 2, 163-171 JOURNAL OF CONTROLLED RELEASE, 31, 2, 163-171 JOURNAL OF CONTROLLED RELEASE, 31, 2, 163-171 1994/09 Refereed English Research paper(scientific journal) Disclose to all
T MORITA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI T MORITA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI T MORITA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI IMPROVEMENT OF THE PULMONARY ABSORPTION OF (ASU(1,7))-EEL CALCITONIN BY VARIOUS PROTEASE INHIBITORS IN RATS IMPROVEMENT OF THE PULMONARY ABSORPTION OF (ASU(1,7))-EEL CALCITONIN BY VARIOUS PROTEASE INHIBITORS IN RATS IMPROVEMENT OF THE PULMONARY ABSORPTION OF (ASU(1,7))-EEL CALCITONIN BY VARIOUS PROTEASE INHIBITORS IN RATS PHARMACEUTICAL RESEARCH, 11, 6, 909-913 PHARMACEUTICAL RESEARCH, 11, 6, 909-913 PHARMACEUTICAL RESEARCH, 11, 6, 909-913 1994/06 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, T FUJITA, H FURITSU, M NISHIKAWA, H SEZAKI, M HASHIDA Y TAKAKURA, T FUJITA, H FURITSU, M NISHIKAWA, H SEZAKI, M HASHIDA Y TAKAKURA, T FUJITA, H FURITSU, M NISHIKAWA, H SEZAKI, M HASHIDA PHARMACOKINETICS OF SUCCINYLATED PROTEINS AND DEXTRAN SULFATE IN MICE - IMPLICATIONS FOR HEPATIC TARGETING OF PROTEIN DRUGS BY DIRECT SUCCINYLATION VIA SCAVENGER RECEPTORS PHARMACOKINETICS OF SUCCINYLATED PROTEINS AND DEXTRAN SULFATE IN MICE - IMPLICATIONS FOR HEPATIC TARGETING OF PROTEIN DRUGS BY DIRECT SUCCINYLATION VIA SCAVENGER RECEPTORS PHARMACOKINETICS OF SUCCINYLATED PROTEINS AND DEXTRAN SULFATE IN MICE - IMPLICATIONS FOR HEPATIC TARGETING OF PROTEIN DRUGS BY DIRECT SUCCINYLATION VIA SCAVENGER RECEPTORS INTERNATIONAL JOURNAL OF PHARMACEUTICS, 105, 1, 19-29 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 105, 1, 19-29 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 105, 1, 19-29 1994/04 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, S MASUDA, H TOKUDA, M NISHIKAWA, M HASHIDA Y TAKAKURA, S MASUDA, H TOKUDA, M NISHIKAWA, M HASHIDA Y TAKAKURA, S MASUDA, H TOKUDA, M NISHIKAWA, M HASHIDA TARGETED DELIVERY OF SUPEROXIDE-DISMUTASE TO MACROPHAGES VIA MANNOSE RECEPTOR-MEDIATED MECHANISM TARGETED DELIVERY OF SUPEROXIDE-DISMUTASE TO MACROPHAGES VIA MANNOSE RECEPTOR-MEDIATED MECHANISM TARGETED DELIVERY OF SUPEROXIDE-DISMUTASE TO MACROPHAGES VIA MANNOSE RECEPTOR-MEDIATED MECHANISM BIOCHEMICAL PHARMACOLOGY, 47, 5, 853-858 BIOCHEMICAL PHARMACOLOGY, 47, 5, 853-858 BIOCHEMICAL PHARMACOLOGY, 47, 5, 853-858 1994/03 Refereed English Research paper(scientific journal) Disclose to all
Y KOYAMA, H BANDO, F YAMASHITA, Y TAKAKURA, H SEZAKI, M HASHIDA Y KOYAMA, H BANDO, F YAMASHITA, Y TAKAKURA, H SEZAKI, M HASHIDA Y KOYAMA, H BANDO, F YAMASHITA, Y TAKAKURA, H SEZAKI, M HASHIDA COMPARATIVE-ANALYSIS OF PERCUTANEOUS-ABSORPTION ENHANCEMENT BY D-LIMONENE AND OLEIC-ACID BASED ON A SKIN DIFFUSION-MODEL COMPARATIVE-ANALYSIS OF PERCUTANEOUS-ABSORPTION ENHANCEMENT BY D-LIMONENE AND OLEIC-ACID BASED ON A SKIN DIFFUSION-MODEL COMPARATIVE-ANALYSIS OF PERCUTANEOUS-ABSORPTION ENHANCEMENT BY D-LIMONENE AND OLEIC-ACID BASED ON A SKIN DIFFUSION-MODEL PHARMACEUTICAL RESEARCH, 11, 3, 377-383 PHARMACEUTICAL RESEARCH, 11, 3, 377-383 PHARMACEUTICAL RESEARCH, 11, 3, 377-383 1994/03 Refereed English Research paper(scientific journal) Disclose to all
K MIHARA, K SAWAI, Y TAKAKURA, M HASHIDA K MIHARA, K SAWAI, Y TAKAKURA, M HASHIDA K MIHARA, K SAWAI, Y TAKAKURA, M HASHIDA MANIPULATION OF RENAL DISPOSITION OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION MANIPULATION OF RENAL DISPOSITION OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION MANIPULATION OF RENAL DISPOSITION OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 2, 296-301 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 2, 296-301 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 2, 296-301 1994/02 Refereed English Research paper(scientific journal) Disclose to all
F YAMASHITA, H BANDO, Y KOYAMA, S KITAGAWA, Y TAKAKURA, M HASHIDA F YAMASHITA, H BANDO, Y KOYAMA, S KITAGAWA, Y TAKAKURA, M HASHIDA F YAMASHITA, H BANDO, Y KOYAMA, S KITAGAWA, Y TAKAKURA, M HASHIDA IN-VIVO AND IN-VITRO ANALYSIS OF SKIN PENETRATION ENHANCEMENT BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM IN-VIVO AND IN-VITRO ANALYSIS OF SKIN PENETRATION ENHANCEMENT BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM IN-VIVO AND IN-VITRO ANALYSIS OF SKIN PENETRATION ENHANCEMENT BASED ON A 2-LAYER DIFFUSION-MODEL WITH POLAR AND NONPOLAR ROUTES IN THE STRATUM-CORNEUM PHARMACEUTICAL RESEARCH, 11, 2, 185-191 PHARMACEUTICAL RESEARCH, 11, 2, 185-191 PHARMACEUTICAL RESEARCH, 11, 2, 185-191 1994/02 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, K MIHARA, M HASHIDA Y TAKAKURA, K MIHARA, M HASHIDA Y TAKAKURA, K MIHARA, M HASHIDA CONTROL OF THE DISPOSITION PROFILES OF PROTEINS IN THE KIDNEY VIA CHEMICAL MODIFICATION CONTROL OF THE DISPOSITION PROFILES OF PROTEINS IN THE KIDNEY VIA CHEMICAL MODIFICATION CONTROL OF THE DISPOSITION PROFILES OF PROTEINS IN THE KIDNEY VIA CHEMICAL MODIFICATION JOURNAL OF CONTROLLED RELEASE, 28, 1-3, 111-119 JOURNAL OF CONTROLLED RELEASE, 28, 1-3, 111-119 JOURNAL OF CONTROLLED RELEASE, 28, 1-3, 111-119 1994/01 Refereed English Research paper(scientific journal) Disclose to all
Y. Takakura, T. Miyao, K. Kawabata, M. Hashida Y. Takakura, T. Miyao, K. Kawabata, M. Hashida Y. Takakura, T. Miyao, K. Kawabata, M. Hashida Control of in vivo characteristics of gene and antisense DNA disposition Control of in vivo characteristics of gene and antisense DNA disposition Control of in vivo characteristics of gene and antisense DNA disposition Japanese Journal of Cancer and Chemotherapy, 21, 3, 320-324 Japanese Journal of Cancer and Chemotherapy, 21, 3, 320-324 Japanese Journal of Cancer and Chemotherapy, 21, 3, 320-324 1994 Refereed English Research paper(international conference proceedings) Disclose to all
T TAKINO, K KONISHI, Y TAKAKURA, M HASHIDA T TAKINO, K KONISHI, Y TAKAKURA, M HASHIDA T TAKINO, K KONISHI, Y TAKAKURA, M HASHIDA LONG CIRCULATING EMULSION CARRIER SYSTEMS FOR HIGHLY LIPOPHILIC DRUGS LONG CIRCULATING EMULSION CARRIER SYSTEMS FOR HIGHLY LIPOPHILIC DRUGS LONG CIRCULATING EMULSION CARRIER SYSTEMS FOR HIGHLY LIPOPHILIC DRUGS BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 1, 121-125 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 1, 121-125 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 1, 121-125 1994/01 Refereed English Research paper(scientific journal) Disclose to all
T FUJITA, M NISHIKAWA, Y OHTSUBO, J OHNO, Y TAKAKURA, H SEZAKI, M HASHIDA T FUJITA, M NISHIKAWA, Y OHTSUBO, J OHNO, Y TAKAKURA, H SEZAKI, M HASHIDA T FUJITA, M NISHIKAWA, Y OHTSUBO, J OHNO, Y TAKAKURA, H SEZAKI, M HASHIDA CONTROL OF IN-VIVO FATE OF ALBUMIN DERIVATIVES UTILIZING COMBINED CHEMICAL MODIFICATION CONTROL OF IN-VIVO FATE OF ALBUMIN DERIVATIVES UTILIZING COMBINED CHEMICAL MODIFICATION CONTROL OF IN-VIVO FATE OF ALBUMIN DERIVATIVES UTILIZING COMBINED CHEMICAL MODIFICATION JOURNAL OF DRUG TARGETING, 2, 2, 157-165 JOURNAL OF DRUG TARGETING, 2, 2, 157-165 JOURNAL OF DRUG TARGETING, 2, 2, 157-165 1994 Refereed English Research paper(scientific journal) Disclose to all
M HASHIDA, M NISHIKAWA, F YAMASHITA, Y TAKAKURA M HASHIDA, M NISHIKAWA, F YAMASHITA, Y TAKAKURA M HASHIDA, M NISHIKAWA, F YAMASHITA, Y TAKAKURA TARGETING DELIVERY OF PROTEIN DRUGS BY CHEMICAL MODIFICATION TARGETING DELIVERY OF PROTEIN DRUGS BY CHEMICAL MODIFICATION TARGETING DELIVERY OF PROTEIN DRUGS BY CHEMICAL MODIFICATION DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 20, 4, 581-590 DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 20, 4, 581-590 DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 20, 4, 581-590 1994 Refereed English Research paper(scientific journal) Disclose to all
K MIHARA, Y OKA, K SAWAI, Y TAKAKURA, M HASHIDA K MIHARA, Y OKA, K SAWAI, Y TAKAKURA, M HASHIDA K MIHARA, Y OKA, K SAWAI, Y TAKAKURA, M HASHIDA IMPROVEMENT OF THERAPEUTIC EFFECT OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE ON ISCHEMIC ACUTE-RENAL-FAILURE IN THE RAT VIA CATIONIZATION AND CONJUGATION WITH POLYETHYLENE-GLYCOL IMPROVEMENT OF THERAPEUTIC EFFECT OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE ON ISCHEMIC ACUTE-RENAL-FAILURE IN THE RAT VIA CATIONIZATION AND CONJUGATION WITH POLYETHYLENE-GLYCOL IMPROVEMENT OF THERAPEUTIC EFFECT OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE ON ISCHEMIC ACUTE-RENAL-FAILURE IN THE RAT VIA CATIONIZATION AND CONJUGATION WITH POLYETHYLENE-GLYCOL JOURNAL OF DRUG TARGETING, 2, 4, 317-321 JOURNAL OF DRUG TARGETING, 2, 4, 317-321 JOURNAL OF DRUG TARGETING, 2, 4, 317-321 1994 Refereed English Research paper(scientific journal) Disclose to all
H TOKUDA, S MASUDA, Y TAKAKURA, H SEZAKI, M HASHIDA H TOKUDA, S MASUDA, Y TAKAKURA, H SEZAKI, M HASHIDA H TOKUDA, S MASUDA, Y TAKAKURA, H SEZAKI, M HASHIDA SPECIFIC UPTAKE OF SUCCINYLATED PROTEINS VIA A SCAVENGER RECEPTOR-MEDIATED MECHANISM IN CULTURED BRAIN MICROVESSEL ENDOTHELIAL-CELLS SPECIFIC UPTAKE OF SUCCINYLATED PROTEINS VIA A SCAVENGER RECEPTOR-MEDIATED MECHANISM IN CULTURED BRAIN MICROVESSEL ENDOTHELIAL-CELLS SPECIFIC UPTAKE OF SUCCINYLATED PROTEINS VIA A SCAVENGER RECEPTOR-MEDIATED MECHANISM IN CULTURED BRAIN MICROVESSEL ENDOTHELIAL-CELLS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 196, 1, 18-24 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 196, 1, 18-24 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 196, 1, 18-24 1993/10 Refereed English Research paper(scientific journal) Disclose to all
M NISHIKAWA, A KAMIJO, T FUJITA, Y TAKAKURA, H SEZAKI, M HASHIDA M NISHIKAWA, A KAMIJO, T FUJITA, Y TAKAKURA, H SEZAKI, M HASHIDA M NISHIKAWA, A KAMIJO, T FUJITA, Y TAKAKURA, H SEZAKI, M HASHIDA SYNTHESIS AND PHARMACOKINETICS OF A NEW LIVER-SPECIFIC CARRIER, GLYCOSYLATED CARBOXYMETHYL-DEXTRAN, AND ITS APPLICATION TO DRUG TARGETING SYNTHESIS AND PHARMACOKINETICS OF A NEW LIVER-SPECIFIC CARRIER, GLYCOSYLATED CARBOXYMETHYL-DEXTRAN, AND ITS APPLICATION TO DRUG TARGETING SYNTHESIS AND PHARMACOKINETICS OF A NEW LIVER-SPECIFIC CARRIER, GLYCOSYLATED CARBOXYMETHYL-DEXTRAN, AND ITS APPLICATION TO DRUG TARGETING PHARMACEUTICAL RESEARCH, 10, 9, 1253-1261 PHARMACEUTICAL RESEARCH, 10, 9, 1253-1261 PHARMACEUTICAL RESEARCH, 10, 9, 1253-1261 1993/09 Refereed English Research paper(scientific journal) Disclose to all
K MIHARA, T HOJO, M FUJIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA K MIHARA, T HOJO, M FUJIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA K MIHARA, T HOJO, M FUJIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA DISPOSITION CHARACTERISTICS OF PROTEIN DRUGS IN THE PERFUSED RAT-KIDNEY DISPOSITION CHARACTERISTICS OF PROTEIN DRUGS IN THE PERFUSED RAT-KIDNEY DISPOSITION CHARACTERISTICS OF PROTEIN DRUGS IN THE PERFUSED RAT-KIDNEY PHARMACEUTICAL RESEARCH, 10, 6, 823-827 PHARMACEUTICAL RESEARCH, 10, 6, 823-827 PHARMACEUTICAL RESEARCH, 10, 6, 823-827 1993/06 Refereed English Research paper(scientific journal) Disclose to all
Toichi Takino, Chisato Nakajima, Yoshinobu Takakura, Hitoshi Sezaki, Mitsuru Hashida Toichi Takino, Chisato Nakajima, Yoshinobu Takakura, Hitoshi Sezaki, Mitsuru Hashida Toichi Takino, Chisato Nakajima, Yoshinobu Takakura, Hitoshi Sezaki, Mitsuru Hashida Controlled Biodistribution of Highly Lipophilic Drugs with Various Parenteral Formulations Controlled Biodistribution of Highly Lipophilic Drugs with Various Parenteral Formulations Controlled Biodistribution of Highly Lipophilic Drugs with Various Parenteral Formulations JOURNAL OF DRUG TARGETING, 1, 2, 117-124 JOURNAL OF DRUG TARGETING, 1, 2, 117-124 JOURNAL OF DRUG TARGETING, 1, 2, 117-124 1993 Refereed English Research paper(scientific journal) Disclose to all
T FUJITA, M NISHIKAWA, C TAMAKI, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, M NISHIKAWA, C TAMAKI, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, M NISHIKAWA, C TAMAKI, Y TAKAKURA, M HASHIDA, H SEZAKI TARGETED DELIVERY OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION WITH MONOSACCHARIDE AND POLYSACCHARIDE DERIVATIVES TARGETED DELIVERY OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION WITH MONOSACCHARIDE AND POLYSACCHARIDE DERIVATIVES TARGETED DELIVERY OF HUMAN RECOMBINANT SUPEROXIDE-DISMUTASE BY CHEMICAL MODIFICATION WITH MONOSACCHARIDE AND POLYSACCHARIDE DERIVATIVES JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 263, 3, 971-978 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 263, 3, 971-978 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 263, 3, 971-978 1992/12 Refereed English Research paper(scientific journal) Disclose to all
T FUJITA, H FURITSU, M NISHIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA T FUJITA, H FURITSU, M NISHIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA T FUJITA, H FURITSU, M NISHIKAWA, Y TAKAKURA, H SEZAKI, M HASHIDA THERAPEUTIC EFFECTS OF SUPEROXIDE-DISMUTASE DERIVATIVES MODIFIED WITH MONOSACCHARIDES OR POLYSACCHARIDES ON HEPATIC-INJURY INDUCED BY ISCHEMIA REPERFUSION THERAPEUTIC EFFECTS OF SUPEROXIDE-DISMUTASE DERIVATIVES MODIFIED WITH MONOSACCHARIDES OR POLYSACCHARIDES ON HEPATIC-INJURY INDUCED BY ISCHEMIA REPERFUSION THERAPEUTIC EFFECTS OF SUPEROXIDE-DISMUTASE DERIVATIVES MODIFIED WITH MONOSACCHARIDES OR POLYSACCHARIDES ON HEPATIC-INJURY INDUCED BY ISCHEMIA REPERFUSION BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 189, 1, 191-196 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 189, 1, 191-196 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 189, 1, 191-196 1992/11 Refereed English Research paper(scientific journal) Disclose to all
H IMOTO, Y SAKAMURA, K OHKOUCHI, R ATSUMI, Y TAKAKURA, H SEZAKI, M HASHIDA H IMOTO, Y SAKAMURA, K OHKOUCHI, R ATSUMI, Y TAKAKURA, H SEZAKI, M HASHIDA H IMOTO, Y SAKAMURA, K OHKOUCHI, R ATSUMI, Y TAKAKURA, H SEZAKI, M HASHIDA DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN THE PERFUSED TISSUE-ISOLATED TUMOR PREPARATION DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN THE PERFUSED TISSUE-ISOLATED TUMOR PREPARATION DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN THE PERFUSED TISSUE-ISOLATED TUMOR PREPARATION CANCER RESEARCH, 52, 16, 4396-4401 CANCER RESEARCH, 52, 16, 4396-4401 CANCER RESEARCH, 52, 16, 4396-4401 1992/08 Refereed English Research paper(scientific journal) Disclose to all
M NISHIKAWA, F YAMASHITA, Y TAKAKURA, M HASHIDA, H SEZAKI M NISHIKAWA, F YAMASHITA, Y TAKAKURA, M HASHIDA, H SEZAKI M NISHIKAWA, F YAMASHITA, Y TAKAKURA, M HASHIDA, H SEZAKI DEMONSTRATION OF THE RECEPTOR-MEDIATED HEPATIC-UPTAKE OF DEXTRAN IN MICE DEMONSTRATION OF THE RECEPTOR-MEDIATED HEPATIC-UPTAKE OF DEXTRAN IN MICE DEMONSTRATION OF THE RECEPTOR-MEDIATED HEPATIC-UPTAKE OF DEXTRAN IN MICE JOURNAL OF PHARMACY AND PHARMACOLOGY, 44, 5, 396-401 JOURNAL OF PHARMACY AND PHARMACOLOGY, 44, 5, 396-401 JOURNAL OF PHARMACY AND PHARMACOLOGY, 44, 5, 396-401 1992/05 Refereed English Research paper(scientific journal) Disclose to all
A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI PREPARATION AND PROPERTIES OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE PREPARATION AND PROPERTIES OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE PREPARATION AND PROPERTIES OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE BIOCONJUGATE CHEMISTRY, 3, 2, 132-137 BIOCONJUGATE CHEMISTRY, 3, 2, 132-137 BIOCONJUGATE CHEMISTRY, 3, 2, 132-137 1992/03 Refereed English Research paper(scientific journal) Disclose to all
H SEZAKI, Y TAKAKURA, M HASHIDA H SEZAKI, Y TAKAKURA, M HASHIDA H SEZAKI, Y TAKAKURA, M HASHIDA CHEMICAL MODIFICATION AND DISPOSITION OF PROTEINS AND PEPTIDES - BIOPHARMACEUTICAL ASPECTS CHEMICAL MODIFICATION AND DISPOSITION OF PROTEINS AND PEPTIDES - BIOPHARMACEUTICAL ASPECTS CHEMICAL MODIFICATION AND DISPOSITION OF PROTEINS AND PEPTIDES - BIOPHARMACEUTICAL ASPECTS TOPICS IN PHARMACEUTICAL SCIENCES 1991, 47-57 TOPICS IN PHARMACEUTICAL SCIENCES 1991, 47-57 TOPICS IN PHARMACEUTICAL SCIENCES 1991, 47-57 1992 Refereed English Research paper(international conference proceedings) Disclose to all
M MASEGI, N WAKABAYASHI, K SAGARA, Y TERAMURA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI M MASEGI, N WAKABAYASHI, K SAGARA, Y TERAMURA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI M MASEGI, N WAKABAYASHI, K SAGARA, Y TERAMURA, A YAMAMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI PERMEABILITY OF MACROMOLECULES IN CULTURED ENDOTHELIAL AND TUMOR-CELL LAYERS ON MICROPOROUS MEMBRANES PERMEABILITY OF MACROMOLECULES IN CULTURED ENDOTHELIAL AND TUMOR-CELL LAYERS ON MICROPOROUS MEMBRANES PERMEABILITY OF MACROMOLECULES IN CULTURED ENDOTHELIAL AND TUMOR-CELL LAYERS ON MICROPOROUS MEMBRANES INTERNATIONAL JOURNAL OF PHARMACEUTICS, 78, 2-3, 103-113 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 78, 2-3, 103-113 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 78, 2-3, 103-113 1992/01 Refereed English Research paper(scientific journal) Disclose to all
Y. Takakura, K.L. Audus, R.T. Borchardt Y. Takakura, K.L. Audus, R.T. Borchardt Y. Takakura, K.L. Audus, R.T. Borchardt Cultured brain microvessel endothelial cells as in vitro models of the blood-brain barrier. Cultured brain microvessel endothelial cells as in vitro models of the blood-brain barrier. Cultured brain microvessel endothelial cells as in vitro models of the blood-brain barrier. NIDA research monograph, 120, 138-152 NIDA research monograph, 120, 138-152 NIDA research monograph, 120, 138-152 1992 Refereed English Disclose to all
Y TAKAKURA, AM TRAMMEL, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT Y TAKAKURA, AM TRAMMEL, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT Y TAKAKURA, AM TRAMMEL, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .2. EFFECTS OF CONDITIONED MEDIA FROM ASTROGLIAL AND GLIOMA-CELLS HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .2. EFFECTS OF CONDITIONED MEDIA FROM ASTROGLIAL AND GLIOMA-CELLS HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .2. EFFECTS OF CONDITIONED MEDIA FROM ASTROGLIAL AND GLIOMA-CELLS BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 11-19 BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 11-19 BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 11-19 1991/11 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT Y TAKAKURA, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT Y TAKAKURA, SL KUENTZEL, TJ RAUB, A DAVIES, SA BALDWIN, RT BORCHARDT HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .1. BASIC CHARACTERISTICS AND EFFECTS OF D-GLUCOSE AND INSULIN HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .1. BASIC CHARACTERISTICS AND EFFECTS OF D-GLUCOSE AND INSULIN HEXOSE UPTAKE IN PRIMARY CULTURES OF BOVINE BRAIN MICROVESSEL ENDOTHELIAL-CELLS .1. BASIC CHARACTERISTICS AND EFFECTS OF D-GLUCOSE AND INSULIN BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 1-10 BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 1-10 BIOCHIMICA ET BIOPHYSICA ACTA, 1070, 1, 1-10 1991/11 Refereed English Research paper(scientific journal) Disclose to all
T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI TISSUE DISTRIBUTION OF IN-111 LABELED URICASE CONJUGATED WITH CHARGED DEXTRANS AND POLYETHYLENE-GLYCOL TISSUE DISTRIBUTION OF IN-111 LABELED URICASE CONJUGATED WITH CHARGED DEXTRANS AND POLYETHYLENE-GLYCOL TISSUE DISTRIBUTION OF IN-111 LABELED URICASE CONJUGATED WITH CHARGED DEXTRANS AND POLYETHYLENE-GLYCOL JOURNAL OF PHARMACOBIO-DYNAMICS, 14, 11, 623-629 JOURNAL OF PHARMACOBIO-DYNAMICS, 14, 11, 623-629 JOURNAL OF PHARMACOBIO-DYNAMICS, 14, 11, 623-629 1991/11 Refereed English Research paper(scientific journal) Disclose to all
K NISHIDA, Y EGUCHI, T TAKINO, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, Y EGUCHI, T TAKINO, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, Y EGUCHI, T TAKINO, Y TAKAKURA, M HASHIDA, H SEZAKI HEPATIC DISPOSITION CHARACTERISTICS OF IN-111 LABELED LACTOSAMINATED BOVINE SERUM-ALBUMIN IN RATS HEPATIC DISPOSITION CHARACTERISTICS OF IN-111 LABELED LACTOSAMINATED BOVINE SERUM-ALBUMIN IN RATS HEPATIC DISPOSITION CHARACTERISTICS OF IN-111 LABELED LACTOSAMINATED BOVINE SERUM-ALBUMIN IN RATS PHARMACEUTICAL RESEARCH, 8, 10, 1253-1257 PHARMACEUTICAL RESEARCH, 8, 10, 1253-1257 PHARMACEUTICAL RESEARCH, 8, 10, 1253-1257 1991/10 Refereed English Research paper(scientific journal) Disclose to all
K NISHIDA, K MIHARA, T TAKINO, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, K MIHARA, T TAKINO, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, K MIHARA, T TAKINO, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI HEPATIC DISPOSITION CHARACTERISTICS OF ELECTRICALLY CHARGED MACROMOLECULES IN RAT INVIVO AND IN THE PERFUSED LIVER HEPATIC DISPOSITION CHARACTERISTICS OF ELECTRICALLY CHARGED MACROMOLECULES IN RAT INVIVO AND IN THE PERFUSED LIVER HEPATIC DISPOSITION CHARACTERISTICS OF ELECTRICALLY CHARGED MACROMOLECULES IN RAT INVIVO AND IN THE PERFUSED LIVER PHARMACEUTICAL RESEARCH, 8, 4, 437-444 PHARMACEUTICAL RESEARCH, 8, 4, 437-444 PHARMACEUTICAL RESEARCH, 8, 4, 437-444 1991/04 Refereed English Research paper(scientific journal) Disclose to all
A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI A NOGUCHI, T TAKAHASHI, T YAMAGUCHI, K KITAMURA, Y TAKAKURA, M HASHIDA, H SEZAKI TUMOR-LOCALIZATION AND INVIVO ANTITUMOR-ACTIVITY OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE TUMOR-LOCALIZATION AND INVIVO ANTITUMOR-ACTIVITY OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE TUMOR-LOCALIZATION AND INVIVO ANTITUMOR-ACTIVITY OF THE IMMUNOCONJUGATE COMPOSED OF ANTI-HUMAN COLON CANCER MONOCLONAL-ANTIBODY AND MITOMYCIN C-DEXTRAN CONJUGATE JAPANESE JOURNAL OF CANCER RESEARCH, 82, 2, 219-226 JAPANESE JOURNAL OF CANCER RESEARCH, 82, 2, 219-226 JAPANESE JOURNAL OF CANCER RESEARCH, 82, 2, 219-226 1991/02 Refereed English Research paper(scientific journal) Disclose to all
Akinori Noguchi, Toshio Takahashi, Kazuya Kitamura, Toskiharu Yamaguchi, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Akinori Noguchi, Toshio Takahashi, Kazuya Kitamura, Toskiharu Yamaguchi, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Akinori Noguchi, Toshio Takahashi, Kazuya Kitamura, Toskiharu Yamaguchi, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Immunoconjugate of monoclonal antibody A7 and mitomycin C-dextran conjugate linked through thioether bond Immunoconjugate of monoclonal antibody A7 and mitomycin C-dextran conjugate linked through thioether bond Immunoconjugate of monoclonal antibody A7 and mitomycin C-dextran conjugate linked through thioether bond Drug Delivery System, 6, 3, 171-175 Drug Delivery System, 6, 3, 171-175 Drug Delivery System, 6, 3, 171-175 1991 Refereed English Research paper(scientific journal) Disclose to all
T. Fujita, Y. Takakura, M. Hashida, H. Sezaki T. Fujita, Y. Takakura, M. Hashida, H. Sezaki T. Fujita, Y. Takakura, M. Hashida, H. Sezaki Control of in vivo fate of protein drugs using chemical modification with sugars Control of in vivo fate of protein drugs using chemical modification with sugars Control of in vivo fate of protein drugs using chemical modification with sugars Journal of Pharmacobio-Dynamics, 14, 2, s-29 Journal of Pharmacobio-Dynamics, 14, 2, s-29 Journal of Pharmacobio-Dynamics, 14, 2, s-29 1991 Refereed English Disclose to all
Yoshinobu Takakura, Kenneth L. Audus, Ronald T. Borchardt Yoshinobu Takakura, Kenneth L. Audus, Ronald T. Borchardt Yoshinobu Takakura, Kenneth L. Audus, Ronald T. Borchardt Blood—Brain Barrier: Transport Studies in Isolated Brain Capillaries and in Cultured Brain Endothelial Cells Blood—Brain Barrier: Transport Studies in Isolated Brain Capillaries and in Cultured Brain Endothelial Cells Blood—Brain Barrier: Transport Studies in Isolated Brain Capillaries and in Cultured Brain Endothelial Cells Advances in Pharmacology, 22, C, 137-165 Advances in Pharmacology, 22, C, 137-165 Advances in Pharmacology, 22, C, 137-165 1991/01/01 Refereed English Research paper(scientific journal) Disclose to all
K NISHIDA, C TONEGAWA, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, C TONEGAWA, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI K NISHIDA, C TONEGAWA, S NAKANE, Y TAKAKURA, M HASHIDA, H SEZAKI EFFECT OF ELECTRIC CHARGE ON THE HEPATIC-UPTAKE OF MACROMOLECULES IN THE RAT-LIVER EFFECT OF ELECTRIC CHARGE ON THE HEPATIC-UPTAKE OF MACROMOLECULES IN THE RAT-LIVER EFFECT OF ELECTRIC CHARGE ON THE HEPATIC-UPTAKE OF MACROMOLECULES IN THE RAT-LIVER INTERNATIONAL JOURNAL OF PHARMACEUTICS, 65, 1-2, 7-17 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 65, 1-2, 7-17 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 65, 1-2, 7-17 1990/11 Refereed English Research paper(scientific journal) Disclose to all
Y YASUDA, T FUJITA, Y TAKAKURA, M HASHIDA, H SEZAKI Y YASUDA, T FUJITA, Y TAKAKURA, M HASHIDA, H SEZAKI Y YASUDA, T FUJITA, Y TAKAKURA, M HASHIDA, H SEZAKI BIOCHEMICAL AND BIOPHARMACEUTICAL PROPERTIES OF MACROMOLECULAR CONJUGATES OF URICASE WITH DEXTRAN AND POLYETHYLENE-GLYCOL BIOCHEMICAL AND BIOPHARMACEUTICAL PROPERTIES OF MACROMOLECULAR CONJUGATES OF URICASE WITH DEXTRAN AND POLYETHYLENE-GLYCOL BIOCHEMICAL AND BIOPHARMACEUTICAL PROPERTIES OF MACROMOLECULAR CONJUGATES OF URICASE WITH DEXTRAN AND POLYETHYLENE-GLYCOL CHEMICAL & PHARMACEUTICAL BULLETIN, 38, 7, 2053-2056 CHEMICAL & PHARMACEUTICAL BULLETIN, 38, 7, 2053-2056 CHEMICAL & PHARMACEUTICAL BULLETIN, 38, 7, 2053-2056 1990/07 Refereed English Disclose to all
M HASHIDA, R ATSUMI, K NISHIDA, S NAKANE, Y TAKAKURA, H SEZAKI M HASHIDA, R ATSUMI, K NISHIDA, S NAKANE, Y TAKAKURA, H SEZAKI M HASHIDA, R ATSUMI, K NISHIDA, S NAKANE, Y TAKAKURA, H SEZAKI BILIARY-EXCRETION OF MITOMYCIN-C DEXTRAN CONJUGATES IN RELATION TO PHYSICOCHEMICAL CHARACTERISTICS OF CARRIER DEXTRAN BILIARY-EXCRETION OF MITOMYCIN-C DEXTRAN CONJUGATES IN RELATION TO PHYSICOCHEMICAL CHARACTERISTICS OF CARRIER DEXTRAN BILIARY-EXCRETION OF MITOMYCIN-C DEXTRAN CONJUGATES IN RELATION TO PHYSICOCHEMICAL CHARACTERISTICS OF CARRIER DEXTRAN JOURNAL OF PHARMACOBIO-DYNAMICS, 13, 7, 441-447 JOURNAL OF PHARMACOBIO-DYNAMICS, 13, 7, 441-447 JOURNAL OF PHARMACOBIO-DYNAMICS, 13, 7, 441-447 1990/07 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, T FUJITA, M HASHIDA, H SEZAKI Y TAKAKURA, T FUJITA, M HASHIDA, H SEZAKI Y TAKAKURA, T FUJITA, M HASHIDA, H SEZAKI DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN TUMOR-BEARING MICE DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN TUMOR-BEARING MICE DISPOSITION CHARACTERISTICS OF MACROMOLECULES IN TUMOR-BEARING MICE PHARMACEUTICAL RESEARCH, 7, 4, 339-346 PHARMACEUTICAL RESEARCH, 7, 4, 339-346 PHARMACEUTICAL RESEARCH, 7, 4, 339-346 1990/04 Refereed English Research paper(scientific journal) Disclose to all
K OHKOUCHI, H IMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI K OHKOUCHI, H IMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI K OHKOUCHI, H IMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI DISPOSITION OF ANTICANCER DRUGS AFTER BOLUS ARTERIAL ADMINISTRATION IN A TISSUE-ISOLATED TUMOR PERFUSION SYSTEM DISPOSITION OF ANTICANCER DRUGS AFTER BOLUS ARTERIAL ADMINISTRATION IN A TISSUE-ISOLATED TUMOR PERFUSION SYSTEM DISPOSITION OF ANTICANCER DRUGS AFTER BOLUS ARTERIAL ADMINISTRATION IN A TISSUE-ISOLATED TUMOR PERFUSION SYSTEM CANCER RESEARCH, 50, 5, 1640-1644 CANCER RESEARCH, 50, 5, 1640-1644 CANCER RESEARCH, 50, 5, 1640-1644 1990/03 Refereed English Research paper(scientific journal) Disclose to all
T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI T FUJITA, Y YASUDA, Y TAKAKURA, M HASHIDA, H SEZAKI ALTERATION OF BIOPHARMACEUTICAL PROPERTIES OF DRUGS BY THEIR CONJUGATION WITH WATER-SOLUBLE MACROMOLECULES - URICASE DEXTRAN CONJUGATE ALTERATION OF BIOPHARMACEUTICAL PROPERTIES OF DRUGS BY THEIR CONJUGATION WITH WATER-SOLUBLE MACROMOLECULES - URICASE DEXTRAN CONJUGATE ALTERATION OF BIOPHARMACEUTICAL PROPERTIES OF DRUGS BY THEIR CONJUGATION WITH WATER-SOLUBLE MACROMOLECULES - URICASE DEXTRAN CONJUGATE JOURNAL OF CONTROLLED RELEASE, 11, 1-3, 149-156 JOURNAL OF CONTROLLED RELEASE, 11, 1-3, 149-156 JOURNAL OF CONTROLLED RELEASE, 11, 1-3, 149-156 1990/01 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI PHYSICOCHEMICAL PROPERTIES AND ANTITUMOR ACTIVITIES OF POLYMERIC PRODRUGS OF MITOMYCIN-C WITH DIFFERENT REGENERATION RATES PHYSICOCHEMICAL PROPERTIES AND ANTITUMOR ACTIVITIES OF POLYMERIC PRODRUGS OF MITOMYCIN-C WITH DIFFERENT REGENERATION RATES PHYSICOCHEMICAL PROPERTIES AND ANTITUMOR ACTIVITIES OF POLYMERIC PRODRUGS OF MITOMYCIN-C WITH DIFFERENT REGENERATION RATES JOURNAL OF CONTROLLED RELEASE, 10, 1, 97-105 JOURNAL OF CONTROLLED RELEASE, 10, 1, 97-105 JOURNAL OF CONTROLLED RELEASE, 10, 1, 97-105 1989/10 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI Y TAKAKURA, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI Y TAKAKURA, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .2. BIOPHARMACEUTICAL AND PHARMACOLOGICAL PROPERTIES CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .2. BIOPHARMACEUTICAL AND PHARMACOLOGICAL PROPERTIES CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .2. BIOPHARMACEUTICAL AND PHARMACOLOGICAL PROPERTIES JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 3, 219-222 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 3, 219-222 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 3, 219-222 1989/03 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, Y KANEKO, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI Y TAKAKURA, Y KANEKO, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI Y TAKAKURA, Y KANEKO, T FUJITA, M HASHIDA, H MAEDA, H SEZAKI CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .1. SYNTHESIS AND CHARACTERIZATION CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .1. SYNTHESIS AND CHARACTERIZATION CONTROL OF PHARMACEUTICAL PROPERTIES OF SOYBEAN TRYPSIN-INHIBITOR BY CONJUGATION WITH DEXTRAN .1. SYNTHESIS AND CHARACTERIZATION JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 2, 117-121 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 2, 117-121 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 2, 117-121 1989/02 Refereed English Research paper(scientific journal) Disclose to all
Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Comparison of polythylene glycol and dextran conjugation with protein drug Comparison of polythylene glycol and dextran conjugation with protein drug Comparison of polythylene glycol and dextran conjugation with protein drug Drug Delivery System, 4, 2, 123-124 Drug Delivery System, 4, 2, 123-124 Drug Delivery System, 4, 2, 123-124 1989 Refereed English Research paper(scientific journal) Disclose to all
Y. Takakura, M. Hashida, H. Sezaki, K. Honda, A. Noguchi, T. Takahashi Y. Takakura, M. Hashida, H. Sezaki, K. Honda, A. Noguchi, T. Takahashi Y. Takakura, M. Hashida, H. Sezaki, K. Honda, A. Noguchi, T. Takahashi Design and evaluation of monoclonal antibody-antitumor agent conjugate Design and evaluation of monoclonal antibody-antitumor agent conjugate Design and evaluation of monoclonal antibody-antitumor agent conjugate Journal of Pharmacobio-Dynamics, 12, 2, s-32 Journal of Pharmacobio-Dynamics, 12, 2, s-32 Journal of Pharmacobio-Dynamics, 12, 2, s-32 1989 Refereed English Disclose to all
K SATO, K ITAKURA, K NISHIDA, Y TAKAKURA, M HASHIDA, H SEZAKI K SATO, K ITAKURA, K NISHIDA, Y TAKAKURA, M HASHIDA, H SEZAKI K SATO, K ITAKURA, K NISHIDA, Y TAKAKURA, M HASHIDA, H SEZAKI DISPOSITION OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE PERFUSED RAT-LIVER DISPOSITION OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE PERFUSED RAT-LIVER DISPOSITION OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE PERFUSED RAT-LIVER JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 1, 11-16 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 1, 11-16 JOURNAL OF PHARMACEUTICAL SCIENCES, 78, 1, 11-16 1989/01 Refereed English Research paper(scientific journal) Disclose to all
Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Soluble macromolecular carriers for the delivery of antitumour drugs Soluble macromolecular carriers for the delivery of antitumour drugs Soluble macromolecular carriers for the delivery of antitumour drugs Advanced Drug Delivery Reviews, 3, 2, 247-266 Advanced Drug Delivery Reviews, 3, 2, 247-266 Advanced Drug Delivery Reviews, 3, 2, 247-266 1989 Refereed English Disclose to all
M HASHIDA, K SATO, Y TAKAKURA, H SEZAKI M HASHIDA, K SATO, Y TAKAKURA, H SEZAKI M HASHIDA, K SATO, Y TAKAKURA, H SEZAKI CHARACTERIZATION OF A LIPOPHILIC PRODRUG OF 5-FLUOROURACIL WITH A CHOLESTEROL PROMOIETY AND ITS APPLICATION TO LIPOSOMES CHARACTERIZATION OF A LIPOPHILIC PRODRUG OF 5-FLUOROURACIL WITH A CHOLESTEROL PROMOIETY AND ITS APPLICATION TO LIPOSOMES CHARACTERIZATION OF A LIPOPHILIC PRODRUG OF 5-FLUOROURACIL WITH A CHOLESTEROL PROMOIETY AND ITS APPLICATION TO LIPOSOMES CHEMICAL & PHARMACEUTICAL BULLETIN, 36, 8, 3186-3189 CHEMICAL & PHARMACEUTICAL BULLETIN, 36, 8, 3186-3189 CHEMICAL & PHARMACEUTICAL BULLETIN, 36, 8, 3186-3189 1988/08 Refereed English Disclose to all
Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Yoshinobu Takakura, Takuya Fujita, Mitsuru Hashida, Hitoshi Sezaki Strategy for tumor targeting by macromolecule-drug conjugates Strategy for tumor targeting by macromolecule-drug conjugates Strategy for tumor targeting by macromolecule-drug conjugates Drug Delivery System, 3, 3, 405-409 Drug Delivery System, 3, 3, 405-409 Drug Delivery System, 3, 3, 405-409 1988 Refereed English Research paper(scientific journal) Disclose to all
A. Noguchi, T. Takahashi, T. Yamaguchi, K. Kitamura, T. Yokota, Y. Takakura, M. Hashida, H. Sezaki A. Noguchi, T. Takahashi, T. Yamaguchi, K. Kitamura, T. Yokota, Y. Takakura, M. Hashida, H. Sezaki A. Noguchi, T. Takahashi, T. Yamaguchi, K. Kitamura, T. Yokota, Y. Takakura, M. Hashida, H. Sezaki Development of monoclonal antibody-drug conjugate A7-MMC utilizing dextran as intermediate carrier Development of monoclonal antibody-drug conjugate A7-MMC utilizing dextran as intermediate carrier Development of monoclonal antibody-drug conjugate A7-MMC utilizing dextran as intermediate carrier International Journal of Immunopharmacology, 10, 1, 33 International Journal of Immunopharmacology, 10, 1, 33 International Journal of Immunopharmacology, 10, 1, 33 1988 Refereed English Research paper(international conference proceedings) Disclose to all
S NAKANE, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI S NAKANE, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI S NAKANE, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI THE ACCUMULATION MECHANISM OF CATIONIC MITOMYCIN C-DEXTRAN CONJUGATES IN THE LIVER - INVIVO CELLULAR-LOCALIZATION AND INVITRO INTERACTION WITH HEPATOCYTES THE ACCUMULATION MECHANISM OF CATIONIC MITOMYCIN C-DEXTRAN CONJUGATES IN THE LIVER - INVIVO CELLULAR-LOCALIZATION AND INVITRO INTERACTION WITH HEPATOCYTES THE ACCUMULATION MECHANISM OF CATIONIC MITOMYCIN C-DEXTRAN CONJUGATES IN THE LIVER - INVIVO CELLULAR-LOCALIZATION AND INVITRO INTERACTION WITH HEPATOCYTES JOURNAL OF PHARMACY AND PHARMACOLOGY, 40, 1, 1-6 JOURNAL OF PHARMACY AND PHARMACOLOGY, 40, 1, 1-6 JOURNAL OF PHARMACY AND PHARMACOLOGY, 40, 1, 1-6 1988/01 Refereed English Research paper(scientific journal) Disclose to all
Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Hitoshi Sezaki, Yoshinobu Takakura, Mitsuru Hashida Control of Biopharmaceutical Properties by Dextran Conjugates Control of Biopharmaceutical Properties by Dextran Conjugates Control of Biopharmaceutical Properties by Dextran Conjugates JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 3, 1, 81-93 JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 3, 1, 81-93 JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 3, 1, 81-93 1988/01 Refereed English Research paper(scientific journal) Disclose to all
R ATSUMI, K ENDO, T KAKUTANI, Y TAKAKURA, M HASHIDA, H SEZAKI R ATSUMI, K ENDO, T KAKUTANI, Y TAKAKURA, M HASHIDA, H SEZAKI R ATSUMI, K ENDO, T KAKUTANI, Y TAKAKURA, M HASHIDA, H SEZAKI DISPOSITION CHARACTERISTICS OF MITOMYCIN-C-DEXTRAN CONJUGATE IN NORMAL AND TUMOR-BEARING MUSCLES OF RABBITS DISPOSITION CHARACTERISTICS OF MITOMYCIN-C-DEXTRAN CONJUGATE IN NORMAL AND TUMOR-BEARING MUSCLES OF RABBITS DISPOSITION CHARACTERISTICS OF MITOMYCIN-C-DEXTRAN CONJUGATE IN NORMAL AND TUMOR-BEARING MUSCLES OF RABBITS CANCER RESEARCH, 47, 21, 5546-5551 CANCER RESEARCH, 47, 21, 5546-5551 CANCER RESEARCH, 47, 21, 5546-5551 1987/11 Refereed English Research paper(scientific journal) Disclose to all
S MATSUMOTO, T SHIGEOKA, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, T SHIGEOKA, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, T SHIGEOKA, Y TAKAKURA, M HASHIDA, H SEZAKI CELLULAR INTERACTION AND INVITRO ANTITUMOR EFFECT OF VARIOUS MITOMYCIN-C PRODRUGS IN MITOMYCIN-C-RESISTANT L1210 LEUKEMIA-CELL LINES CELLULAR INTERACTION AND INVITRO ANTITUMOR EFFECT OF VARIOUS MITOMYCIN-C PRODRUGS IN MITOMYCIN-C-RESISTANT L1210 LEUKEMIA-CELL LINES CELLULAR INTERACTION AND INVITRO ANTITUMOR EFFECT OF VARIOUS MITOMYCIN-C PRODRUGS IN MITOMYCIN-C-RESISTANT L1210 LEUKEMIA-CELL LINES CHEMICAL & PHARMACEUTICAL BULLETIN, 35, 9, 3792-3799 CHEMICAL & PHARMACEUTICAL BULLETIN, 35, 9, 3792-3799 CHEMICAL & PHARMACEUTICAL BULLETIN, 35, 9, 3792-3799 1987/09 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, A TAKAGI, M HASHIDA, H SEZAKI Y TAKAKURA, A TAKAGI, M HASHIDA, H SEZAKI Y TAKAKURA, A TAKAGI, M HASHIDA, H SEZAKI DISPOSITION AND TUMOR-LOCALIZATION OF MITOMYCIN-C DEXTRAN CONJUGATES IN MICE DISPOSITION AND TUMOR-LOCALIZATION OF MITOMYCIN-C DEXTRAN CONJUGATES IN MICE DISPOSITION AND TUMOR-LOCALIZATION OF MITOMYCIN-C DEXTRAN CONJUGATES IN MICE PHARMACEUTICAL RESEARCH, 4, 4, 293-300 PHARMACEUTICAL RESEARCH, 4, 4, 293-300 PHARMACEUTICAL RESEARCH, 4, 4, 293-300 1987/08 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, R ATSUMI, M HASHIDA, H SEZAKI Y TAKAKURA, R ATSUMI, M HASHIDA, H SEZAKI Y TAKAKURA, R ATSUMI, M HASHIDA, H SEZAKI DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .2. DISPOSITION AND PHARMACOKINETICS FOLLOWING INTRAVENOUS AND INTRAMUSCULAR ADMINISTRATION DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .2. DISPOSITION AND PHARMACOKINETICS FOLLOWING INTRAVENOUS AND INTRAMUSCULAR ADMINISTRATION DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .2. DISPOSITION AND PHARMACOKINETICS FOLLOWING INTRAVENOUS AND INTRAMUSCULAR ADMINISTRATION INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 145-154 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 145-154 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 145-154 1987/06 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, M KITAJIMA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, M KITAJIMA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, M KITAJIMA, S MATSUMOTO, M HASHIDA, H SEZAKI DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .1. PHYSICOCHEMICAL CHARACTERISTICS AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .1. PHYSICOCHEMICAL CHARACTERISTICS AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES DEVELOPMENT OF A NOVEL POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE WITH ANIONIC CHARGE .1. PHYSICOCHEMICAL CHARACTERISTICS AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 135-143 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 135-143 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 37, 1-2, 135-143 1987/06 Refereed English Research paper(scientific journal) Disclose to all
S MATSUMOTO, A YAMAMOTO, Y TAKAKURA, M HASHIDA, N TANIGAWA, H SEZAKI S MATSUMOTO, A YAMAMOTO, Y TAKAKURA, M HASHIDA, N TANIGAWA, H SEZAKI S MATSUMOTO, A YAMAMOTO, Y TAKAKURA, M HASHIDA, N TANIGAWA, H SEZAKI CELLULAR INTERACTION AND INVITRO ANTITUMOR-ACTIVITY OF MITOMYCIN C-DEXTRAN CONJUGATE CELLULAR INTERACTION AND INVITRO ANTITUMOR-ACTIVITY OF MITOMYCIN C-DEXTRAN CONJUGATE CELLULAR INTERACTION AND INVITRO ANTITUMOR-ACTIVITY OF MITOMYCIN C-DEXTRAN CONJUGATE CANCER RESEARCH, 46, 9, 4463-4468 CANCER RESEARCH, 46, 9, 4463-4468 CANCER RESEARCH, 46, 9, 4463-4468 1986/09 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, K MORI, M HASHIDA, H SEZAKI Y TAKAKURA, K MORI, M HASHIDA, H SEZAKI Y TAKAKURA, K MORI, M HASHIDA, H SEZAKI ABSORPTION CHARACTERISTICS OF MACROMOLECULAR PRODRUGS OF MITOMYCIN-C FOLLOWING INTRAMUSCULAR ADMINISTRATION ABSORPTION CHARACTERISTICS OF MACROMOLECULAR PRODRUGS OF MITOMYCIN-C FOLLOWING INTRAMUSCULAR ADMINISTRATION ABSORPTION CHARACTERISTICS OF MACROMOLECULAR PRODRUGS OF MITOMYCIN-C FOLLOWING INTRAMUSCULAR ADMINISTRATION CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 4, 1775-1783 CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 4, 1775-1783 CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 4, 1775-1783 1986/04 Refereed English Research paper(scientific journal) Disclose to all
S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI CELLULAR INTERACTION AND ANTITUMOR-ACTIVITY OF MITOMYCIN-C PRODRUGS CELLULAR INTERACTION AND ANTITUMOR-ACTIVITY OF MITOMYCIN-C PRODRUGS CELLULAR INTERACTION AND ANTITUMOR-ACTIVITY OF MITOMYCIN-C PRODRUGS JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 6, S140-S140 JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 6, S140-S140 JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 6, S140-S140 1985 Refereed English Disclose to all
T OHSAWA, Y MATSUKAWA, Y TAKAKURA, M HASHIDA, H SEZAKI T OHSAWA, Y MATSUKAWA, Y TAKAKURA, M HASHIDA, H SEZAKI T OHSAWA, Y MATSUKAWA, Y TAKAKURA, M HASHIDA, H SEZAKI FATE OF LIPID AND ENCAPSULATED DRUG AFTER INTRAMUSCULAR ADMINISTRATION OF LIPOSOMES PREPARED BY THE FREEZE-THAWING METHOD IN RATS FATE OF LIPID AND ENCAPSULATED DRUG AFTER INTRAMUSCULAR ADMINISTRATION OF LIPOSOMES PREPARED BY THE FREEZE-THAWING METHOD IN RATS FATE OF LIPID AND ENCAPSULATED DRUG AFTER INTRAMUSCULAR ADMINISTRATION OF LIPOSOMES PREPARED BY THE FREEZE-THAWING METHOD IN RATS CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 11, 5013-5022 CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 11, 5013-5022 CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 11, 5013-5022 1985 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, A KATO, M HASHIDA, K HONDA, A ARIMOTO, K SATOMURA, H SEZAKI Y TAKAKURA, A KATO, M HASHIDA, K HONDA, A ARIMOTO, K SATOMURA, H SEZAKI Y TAKAKURA, A KATO, M HASHIDA, K HONDA, A ARIMOTO, K SATOMURA, H SEZAKI URINARY-EXCRETION CHARACTERISTICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN C-DEXTRAN CONJUGATE URINARY-EXCRETION CHARACTERISTICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN C-DEXTRAN CONJUGATE URINARY-EXCRETION CHARACTERISTICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN C-DEXTRAN CONJUGATE JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 5, 357-364 JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 5, 357-364 JOURNAL OF PHARMACOBIO-DYNAMICS, 8, 5, 357-364 1985 Refereed English Research paper(scientific journal) Disclose to all
S MATSUMOTO, Y ARASE, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, Y ARASE, Y TAKAKURA, M HASHIDA, H SEZAKI S MATSUMOTO, Y ARASE, Y TAKAKURA, M HASHIDA, H SEZAKI PLASMA DISPOSITION AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO THE MODE OF ACTION PLASMA DISPOSITION AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO THE MODE OF ACTION PLASMA DISPOSITION AND INVIVO AND INVITRO ANTITUMOR ACTIVITIES OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO THE MODE OF ACTION CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 7, 2941-2947 CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 7, 2941-2947 CHEMICAL & PHARMACEUTICAL BULLETIN, 33, 7, 2941-2947 1985 Refereed English Research paper(scientific journal) Disclose to all
H SASAKI, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI H SASAKI, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI H SASAKI, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI ANTITUMOR-ACTIVITY OF LIPOPHILIC PRODRUGS OF MITOMYCIN-C ENTRAPPED IN LIPOSOME OR O/W EMULSION ANTITUMOR-ACTIVITY OF LIPOPHILIC PRODRUGS OF MITOMYCIN-C ENTRAPPED IN LIPOSOME OR O/W EMULSION ANTITUMOR-ACTIVITY OF LIPOPHILIC PRODRUGS OF MITOMYCIN-C ENTRAPPED IN LIPOSOME OR O/W EMULSION JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 2, 120-130 JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 2, 120-130 JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 2, 120-130 1984 Refereed English Research paper(scientific journal) Disclose to all
M HASHIDA, A KATO, Y TAKAKURA, H SEZAKI M HASHIDA, A KATO, Y TAKAKURA, H SEZAKI M HASHIDA, A KATO, Y TAKAKURA, H SEZAKI DISPOSITION AND PHARMACOKINETICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE RAT DISPOSITION AND PHARMACOKINETICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE RAT DISPOSITION AND PHARMACOKINETICS OF A POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE, IN THE RAT DRUG METABOLISM AND DISPOSITION, 12, 4, 492-499 DRUG METABOLISM AND DISPOSITION, 12, 4, 492-499 DRUG METABOLISM AND DISPOSITION, 12, 4, 492-499 1984 Refereed English Research paper(scientific journal) Disclose to all
CF ROOS, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI CF ROOS, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI CF ROOS, S MATSUMOTO, Y TAKAKURA, M HASHIDA, H SEZAKI PHYSICOCHEMICAL AND ANTITUMOR CHARACTERISTICS OF SOME POLYAMINO ACID PRODRUGS OF MITOMYCIN-C PHYSICOCHEMICAL AND ANTITUMOR CHARACTERISTICS OF SOME POLYAMINO ACID PRODRUGS OF MITOMYCIN-C PHYSICOCHEMICAL AND ANTITUMOR CHARACTERISTICS OF SOME POLYAMINO ACID PRODRUGS OF MITOMYCIN-C INTERNATIONAL JOURNAL OF PHARMACEUTICS, 22, 1, 75-87 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 22, 1, 75-87 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 22, 1, 75-87 1984 Refereed English Research paper(scientific journal) Disclose to all
Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI Y TAKAKURA, S MATSUMOTO, M HASHIDA, H SEZAKI ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C CONJUGATED WITH DEXTRAN ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C CONJUGATED WITH DEXTRAN ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C CONJUGATED WITH DEXTRAN CANCER RESEARCH, 44, 6, 2505-2510 CANCER RESEARCH, 44, 6, 2505-2510 CANCER RESEARCH, 44, 6, 2505-2510 1984 Refereed English Research paper(scientific journal) Disclose to all
M HASHIDA, Y TAKAKURA, S MATSUMOTO, H SASAKI, A KATO, T KOJIMA, S MURANISHI, H SEZAKI M HASHIDA, Y TAKAKURA, S MATSUMOTO, H SASAKI, A KATO, T KOJIMA, S MURANISHI, H SEZAKI M HASHIDA, Y TAKAKURA, S MATSUMOTO, H SASAKI, A KATO, T KOJIMA, S MURANISHI, H SEZAKI REGENERATION CHARACTERISTICS OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO ITS ACTIVITY REGENERATION CHARACTERISTICS OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO ITS ACTIVITY REGENERATION CHARACTERISTICS OF MITOMYCIN C-DEXTRAN CONJUGATE IN RELATION TO ITS ACTIVITY CHEMICAL & PHARMACEUTICAL BULLETIN, 31, 6, 2055-2063 CHEMICAL & PHARMACEUTICAL BULLETIN, 31, 6, 2055-2063 CHEMICAL & PHARMACEUTICAL BULLETIN, 31, 6, 2055-2063 1983 Refereed English Research paper(scientific journal) Disclose to all
A KATO, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI A KATO, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI A KATO, Y TAKAKURA, M HASHIDA, T KIMURA, H SEZAKI PHYSICOCHEMICAL AND ANTI-TUMOR CHARACTERISTICS OF HIGH MOLECULAR-WEIGHT PRODRUGS OF MITOMYCIN-C PHYSICOCHEMICAL AND ANTI-TUMOR CHARACTERISTICS OF HIGH MOLECULAR-WEIGHT PRODRUGS OF MITOMYCIN-C PHYSICOCHEMICAL AND ANTI-TUMOR CHARACTERISTICS OF HIGH MOLECULAR-WEIGHT PRODRUGS OF MITOMYCIN-C CHEMICAL & PHARMACEUTICAL BULLETIN, 30, 8, 2951-2957 CHEMICAL & PHARMACEUTICAL BULLETIN, 30, 8, 2951-2957 CHEMICAL & PHARMACEUTICAL BULLETIN, 30, 8, 2951-2957 1982 Refereed English Research paper(scientific journal) Disclose to all

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Title language:
Misc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Significant advance in DDS science Significant advance in DDS science Significant advance in DDS science Drug Delivery System, 32, 1, 3 Drug Delivery System, 32, 1, 3 Drug Delivery System, 32, 1, 3 2017 Japanese Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
齋藤昌朗, 野村大貴, 菅田謙治, 松岡雅雄, 高橋洋介, 佐野紘平, 佐治英郎, 高橋有己, 高倉喜信, 西川元也 齋藤昌朗, 野村大貴, 菅田謙治, 松岡雅雄, 高橋洋介, 佐野紘平, 佐治英郎, 高橋有己, 高倉喜信, 西川元也 齋藤昌朗, 野村大貴, 菅田謙治, 松岡雅雄, 高橋洋介, 佐野紘平, 佐治英郎, 高橋有己, 高倉喜信, 西川元也 自然免疫活性化による感染症予防を目的としたCpG DNA徐放DNAハイドロゲルの開発 自然免疫活性化による感染症予防を目的としたCpG DNA徐放DNAハイドロゲルの開発 自然免疫活性化による感染症予防を目的としたCpG DNA徐放DNAハイドロゲルの開発 日本核酸医薬学会年会講演要旨集, 2nd, 100 日本核酸医薬学会年会講演要旨集, 2nd, 100 日本核酸医薬学会年会講演要旨集, 2nd, 100 2016/11/01 Japanese Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura For further evolution of drug delivery system For further evolution of drug delivery system For further evolution of drug delivery system Drug Delivery System, 31, 1, 3 Drug Delivery System, 31, 1, 3 Drug Delivery System, 31, 1, 3 2016/04/25 Japanese Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
山下 富義, 入江 徹美, 新田 淳美, 高倉 喜信, 赤池 昭紀 山下 富義, 入江 徹美, 新田 淳美, 高倉 喜信, 赤池 昭紀 山下 富義, 入江 徹美, 新田 淳美, 高倉 喜信, 赤池 昭紀 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 日本薬学会年会要旨集, 136年会, 1, 214-214 日本薬学会年会要旨集, 136年会, 1, 214-214 日本薬学会年会要旨集, 136年会, 1, 214-214 2016/03 Japanese Disclose to all
森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 【生体膜シンポジウム「細胞外ベクシル・エクソソーム研究の最前線」】 DDSに資するエクソソームの開発 【生体膜シンポジウム「細胞外ベクシル・エクソソーム研究の最前線」】 DDSに資するエクソソームの開発 【生体膜シンポジウム「細胞外ベクシル・エクソソーム研究の最前線」】 DDSに資するエクソソームの開発 膜, 40, 5, 248-253 膜, 40, 5, 248-253 膜, 40, 5, 248-253 2015/09 Japanese Disclose to all
入江 徹美, 新田 淳美, 山下 富義, 栄田 敏之, 高倉 喜信, 赤池 昭紀 入江 徹美, 新田 淳美, 山下 富義, 栄田 敏之, 高倉 喜信, 赤池 昭紀 入江 徹美, 新田 淳美, 山下 富義, 栄田 敏之, 高倉 喜信, 赤池 昭紀 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 先導的薬剤師養成に向けた実践的アドバンスト教育プログラムの共同開発 SP養成・PBLチュートリアル教育プログラム及び高度医療人養成・レギュラトリーサイエンスプログラム 日本薬学会年会要旨集, 135年会, 1, 232-232 日本薬学会年会要旨集, 135年会, 1, 232-232 日本薬学会年会要旨集, 135年会, 1, 232-232 2015/03 Japanese Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Towards the next decade, next two decade and further future Towards the next decade, next two decade and further future Towards the next decade, next two decade and further future Drug Delivery System, 30, 1, 5 Drug Delivery System, 30, 1, 5 Drug Delivery System, 30, 1, 5 2015 Japanese Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
西川元也, 高橋有己, 高倉喜信 西川元也, 高橋有己, 高倉喜信 核酸医薬のための次世代DDS開発 核酸医薬のための次世代DDS開発 PHARM TECH JAPAN, 31, 417-423 PHARM TECH JAPAN, 31, 417-423 , 31, 417-423 2015/01 Japanese Disclose to all
高橋有己, 西川元也, 高倉喜信 高橋有己, 西川元也, 高倉喜信 クローズアップ実験法 ハイドロダイナミクス法-高効率なin vivo遺伝子導入法 クローズアップ実験法 ハイドロダイナミクス法-高効率なin vivo遺伝子導入法 実験医学, 33, 2633-2637 実験医学, 33, 2633-2637 , 33, 2633-2637 2015/01 Japanese Disclose to all
Yusuke Sanada, Shunsuke Salamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Naoto Yagi, Makiya Nishikawa, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Shunsuke Salamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Naoto Yagi, Makiya Nishikawa, Yoshinobu Takakura, Kazuo Sakurai Yusuke Sanada, Shunsuke Salamoto, Tomoki Shiomi, Tadashi Okobira, Efstratios Mylonas, Naoto Yagi, Makiya Nishikawa, Yoshinobu Takakura, Kazuo Sakurai X-ray scattering from tetrapod-shaped DNA in aqueous solution to determine its structures relating to biological activity X-ray scattering from tetrapod-shaped DNA in aqueous solution to determine its structures relating to biological activity X-ray scattering from tetrapod-shaped DNA in aqueous solution to determine its structures relating to biological activity ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248 2014/08 English Research paper, summary (international conference) Disclose to all
森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 森下 将輝, 高橋 有己, 西川 元也, 高倉 喜信 【脂質から形成されるナノマテリアル】 Exosomeの特性とexosomeを利用した診断・治療法の開発 【脂質から形成されるナノマテリアル】 Exosomeの特性とexosomeを利用した診断・治療法の開発 【脂質から形成されるナノマテリアル】 Exosomeの特性とexosomeを利用した診断・治療法の開発 オレオサイエンス, 14, 7, 291-298 オレオサイエンス, 14, 7, 291-298 オレオサイエンス, 14, 7, 291-298 2014/07 Japanese Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura The 30th anniversary of the JSDDS The 30th anniversary of the JSDDS The 30th anniversary of the JSDDS Drug Delivery System, 29, 1, 5 Drug Delivery System, 29, 1, 5 Drug Delivery System, 29, 1, 5 2014 Japanese Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
Yusuke SANADA, Shunsuke SAKAMOTO, Tomoki SHIOMI, Tadashi OKOBIRA, Efstratios MYLONAS, Naoto YAGI, Makiya NISHIKAWA, Yoshinobu TAKAKURA, Kazuo SAKURAI Yusuke SANADA, Shunsuke SAKAMOTO, Tomoki SHIOMI, Tadashi OKOBIRA, Efstratios MYLONAS, Naoto YAGI, Makiya NISHIKAWA, Yoshinobu TAKAKURA, Kazuo SAKURAI Yusuke SANADA, Shunsuke SAKAMOTO, Tomoki SHIOMI, Tadashi OKOBIRA, Efstratios MYLONAS, Naoto YAGI, Makiya NISHIKAWA, Yoshinobu TAKAKURA, Kazuo SAKURAI Structural Analysis of Polypod DNA by Small-Angle X-ray Structural Analysis of Polypod DNA by Small-Angle X-ray Structural Analysis of Polypod DNA by Small-Angle X-ray 第63回高分子学会年次大会 第63回高分子学会年次大会 2014 Disclose to all
Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura 高橋有己, 西川元也, 高倉喜信 Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura In vivo fate of exogenously-administered exosomes エクソソームの体内動態 In vivo fate of exogenously-administered exosomes Drug Delivery System, 29, 2, 116-124 Drug Delivery System, 29, 2, 116-124 Drug Delivery System, 29, 2, 116-124 2014 Refereed English Disclose to all
高橋有己, 西川元也, 高倉喜信 高橋有己, 西川元也, 高倉喜信 高橋有己, 西川元也, 高倉喜信 バイオ医薬品の動態制御 バイオ医薬品の動態制御 バイオ医薬品の動態制御 薬剤学, 74, 1, 27-32 薬剤学, 74, 1, 27-32 薬剤学, 74, 1, 27-32 2014 Refereed Disclose to all
西川元也, 毛利浩太, 高倉喜信 西川元也, 毛利浩太, 高倉喜信 DNAハイドロゲル DNAハイドロゲル 遺伝子医学MOOK別冊「ここまで広がるドラッグ徐放技術の最前線-古くて新しいドラッグデリバリーシステム(DDS)-」, 0, 131-136 遺伝子医学MOOK別冊「ここまで広がるドラッグ徐放技術の最前線-古くて新しいドラッグデリバリーシステム(DDS)-」, 0, 131-136 , 0, 131-136 2013/01 Japanese Disclose to all
Yoshinobu Takakura Yoshinobu Takakura Yoshinobu Takakura Professor Mitsuru Hashida: His outstanding achievements in drug delivery research Professor Mitsuru Hashida: His outstanding achievements in drug delivery research Professor Mitsuru Hashida: His outstanding achievements in drug delivery research JOURNAL OF DRUG TARGETING, 20, 9, 722-723 JOURNAL OF DRUG TARGETING, 20, 9, 722-723 JOURNAL OF DRUG TARGETING, 20, 9, 722-723 2012/11 English Other Disclose to all
Yuki Takahashi, Misturu Ando, Makiya Nishikawa, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Yuki Takahashi, Misturu Ando, Makiya Nishikawa, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Yuki Takahashi, Misturu Ando, Makiya Nishikawa, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Yoshinobu Takakura Long-Term Elimination of Human Hepatitis C Virus in Human Hepatocyte Chimeric Mice after Single Administration of Plasmid DNA Expressing Human Interferon-gamma Long-Term Elimination of Human Hepatitis C Virus in Human Hepatocyte Chimeric Mice after Single Administration of Plasmid DNA Expressing Human Interferon-gamma Long-Term Elimination of Human Hepatitis C Virus in Human Hepatocyte Chimeric Mice after Single Administration of Plasmid DNA Expressing Human Interferon-gamma MOLECULAR THERAPY, 20, S37-S37 MOLECULAR THERAPY, 20, S37-S37 MOLECULAR THERAPY, 20, S37-S37 2012/05 English Research paper, summary (international conference) Disclose to all
高橋有己, 西川元也, 高倉喜信 高橋有己, 西川元也, 高倉喜信 RNA干渉を利用した疾患治療システム RNA干渉を利用した疾患治療システム 生体の科学, 63, 2, 120-128 生体の科学, 63, 2, 120-128 , 63, 2, 120-128 2012/03 Japanese Disclose to all
安藤満, 高橋有己, 西川元也, 高倉喜信 安藤満, 高橋有己, 西川元也, 高倉喜信 機能性ペプチド融合によるInterferon ?時空間制御 機能性ペプチド融合によるInterferon ?時空間制御 YAKUGAKU ZASSHI, 132, 1399-1406 YAKUGAKU ZASSHI, 132, 1399-1406 , 132, 1399-1406 2012/01 Japanese Disclose to all
西川元也, 毛利浩太, 高橋有己, 高倉喜信 西川元也, 毛利浩太, 高橋有己, 高倉喜信 核酸ナノデバイスの開発とDDS応用 核酸ナノデバイスの開発とDDS応用 遺伝子医学MOOK20号「ナノバイオ技術と最新創薬応用研究」, 0, 144-148 遺伝子医学MOOK20号「ナノバイオ技術と最新創薬応用研究」, 0, 144-148 , 0, 144-148 2012/01 Japanese Disclose to all
西川元也, 高倉喜信 西川元也, 高倉喜信 フォーラム 遺伝子・細胞製剤フォーカスグループの活動について フォーラム 遺伝子・細胞製剤フォーカスグループの活動について 薬剤学, 72, 268-269 薬剤学, 72, 268-269 , 72, 268-269 2012/01 Japanese Disclose to all
Makiya Nishikawa, Kohta Mohri, Kohei Ogawa, Natsuki Takahashi, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Kohta Mohri, Kohei Ogawa, Natsuki Takahashi, Yuki Takahashi, Yoshinobu Takakura Makiya Nishikawa, Kohta Mohri, Kohei Ogawa, Natsuki Takahashi, Yuki Takahashi, Yoshinobu Takakura DEVELOPMENT OF DNA NANOGELS AND HYDROGELS AS INJECTABLE DELIVERY SYSTEMS FOR CPG DNA AND OTHER NUCLEIC ACID-BASED DRUGS DEVELOPMENT OF DNA NANOGELS AND HYDROGELS AS INJECTABLE DELIVERY SYSTEMS FOR CPG DNA AND OTHER NUCLEIC ACID-BASED DRUGS DEVELOPMENT OF DNA NANOGELS AND HYDROGELS AS INJECTABLE DELIVERY SYSTEMS FOR CPG DNA AND OTHER NUCLEIC ACID-BASED DRUGS NUCLEIC ACID THERAPEUTICS, 21, 5, A39-A39 NUCLEIC ACID THERAPEUTICS, 21, 5, A39-A39 NUCLEIC ACID THERAPEUTICS, 21, 5, A39-A39 2011/10 English Research paper, summary (international conference) Disclose to all
Yuki Takahashi, Yuriko Matsui, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Yuriko Matsui, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Yuriko Matsui, Makiya Nishikawa, Yoshinobu Takakura KINETIC COMPARISON OF GENE SILENCING PROFILE OF SIRNA AND SHRNA-EXPRESSING PLASMID DNA IN VIVO KINETIC COMPARISON OF GENE SILENCING PROFILE OF SIRNA AND SHRNA-EXPRESSING PLASMID DNA IN VIVO KINETIC COMPARISON OF GENE SILENCING PROFILE OF SIRNA AND SHRNA-EXPRESSING PLASMID DNA IN VIVO NUCLEIC ACID THERAPEUTICS, 21, 5, A28-A29 NUCLEIC ACID THERAPEUTICS, 21, 5, A28-A29 NUCLEIC ACID THERAPEUTICS, 21, 5, A28-A29 2011/10 English Research paper, summary (international conference) Disclose to all
西崎智香, 矢田智也, 西川元也, 奥公秀, 由里本博也, 阪井康能, 高倉喜信 西崎智香, 矢田智也, 西川元也, 奥公秀, 由里本博也, 阪井康能, 高倉喜信 西崎智香, 矢田智也, 西川元也, 奥公秀, 由里本博也, 阪井康能, 高倉喜信 細胞親和性ペプチド融合による動態制御型ヒトカタラーゼの開発とその癌転移抑制効果 細胞親和性ペプチド融合による動態制御型ヒトカタラーゼの開発とその癌転移抑制効果 細胞親和性ペプチド融合による動態制御型ヒトカタラーゼの開発とその癌転移抑制効果 Drug Deliv Syst, 25, 3, 299-299 Drug Deliv Syst, 25, 3, 299-299 Drug Deliv Syst, 25, 3, 299-299 2010/05/28 Japanese Disclose to all
Kayoko Hattori, Makiya Nishikawa, Akihiko Ikoma, Kenji Kabashima, Rei Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Kayoko Hattori, Makiya Nishikawa, Akihiko Ikoma, Kenji Kabashima, Rei Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Kayoko Hattori, Makiya Nishikawa, Akihiko Ikoma, Kenji Kabashima, Rei Takahashi, Yoshihiko Watanabe, Yoshinobu Takakura Increasing the Duration of Transgene Expression of Interferon y for Amelioration of Atopic Dermatitis in NC/Nga Mice Increasing the Duration of Transgene Expression of Interferon y for Amelioration of Atopic Dermatitis in NC/Nga Mice Increasing the Duration of Transgene Expression of Interferon y for Amelioration of Atopic Dermatitis in NC/Nga Mice MOLECULAR THERAPY, 17, S247-S247 MOLECULAR THERAPY, 17, S247-S247 MOLECULAR THERAPY, 17, S247-S247 2009/05 English Research paper, summary (international conference) Disclose to all
Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Nana Takasuka, Kayoko Hattori, Makiya Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells (vol 99, pg 1650, 2008) Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells (vol 99, pg 1650, 2008) Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells (vol 99, pg 1650, 2008) CANCER SCIENCE, 99, 10, 2106-2106 CANCER SCIENCE, 99, 10, 2106-2106 CANCER SCIENCE, 99, 10, 2106-2106 2008/10 English Other Disclose to all
Keita Un, Takaaki Nakao, Ken-ichi Ogawara, Makiya Nishikawa, Yoshinobu Takakura, Kazutaka Higaki, Toshikiro Kimura Keita Un, Takaaki Nakao, Ken-ichi Ogawara, Makiya Nishikawa, Yoshinobu Takakura, Kazutaka Higaki, Toshikiro Kimura Keita Un, Takaaki Nakao, Ken-ichi Ogawara, Makiya Nishikawa, Yoshinobu Takakura, Kazutaka Higaki, Toshikiro Kimura IN VIVO ANTI-TUMOR EFFECTS OF PEG-MODIFIED LIPOSOMAL DOXORUBICIN ON p-GLYCOPROTEIN OVER-EXPRESSING TUMOR-BEARING MICE IN VIVO ANTI-TUMOR EFFECTS OF PEG-MODIFIED LIPOSOMAL DOXORUBICIN ON p-GLYCOPROTEIN OVER-EXPRESSING TUMOR-BEARING MICE IN VIVO ANTI-TUMOR EFFECTS OF PEG-MODIFIED LIPOSOMAL DOXORUBICIN ON p-GLYCOPROTEIN OVER-EXPRESSING TUMOR-BEARING MICE DRUG METABOLISM REVIEWS, 39, 199-199 DRUG METABOLISM REVIEWS, 39, 199-199 DRUG METABOLISM REVIEWS, 39, 199-199 2007 English Research paper, summary (international conference) Disclose to all
Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura 西川元也, 高橋有己, 高倉喜信 Makiya Nishikawa, Yuki Takahashi, Yoshinobu Takakura Delivery of vectors expressing short hairpin RNA for cancer therapy 遺伝子・核酸医薬品のデリバリー がん治療のための short hairpin RNA 発現ベクターのデリバリー Delivery of vectors expressing short hairpin RNA for cancer therapy Drug Delivery System, 22, 2, 123-130 Drug Delivery System, 22, 2, 123-130 Drug Delivery System, 22, 2, 123-130 2007 Refereed English Disclose to all
町田一哉, 西川元也, 光井優, 高橋有己, 高倉喜信 町田一哉, 西川元也, 光井優, 高橋有己, 高倉喜信 町田一哉, 西川元也, 光井優, 高橋有己, 高倉喜信 プラスミドベクターおよび投与方法の最適化によるインターフェロン遺伝子治療効果の増強 プラスミドベクターおよび投与方法の最適化によるインターフェロン遺伝子治療効果の増強 プラスミドベクターおよび投与方法の最適化によるインターフェロン遺伝子治療効果の増強 薬剤学= Journal of Pharmaceutical Science and Technology, Japan, 67, 302 薬剤学= Journal of Pharmaceutical Science and Technology, Japan, 67, 302 薬剤学= Journal of Pharmaceutical Science and Technology, Japan, 67, 302 2007 Refereed Disclose to all
Takayuki Otsuki, Makiya Nishikawa, Atsushi Ota, Seiji Takemoto, Yoshinobu Takakura Takayuki Otsuki, Makiya Nishikawa, Atsushi Ota, Seiji Takemoto, Yoshinobu Takakura Takayuki Otsuki, Makiya Nishikawa, Atsushi Ota, Seiji Takemoto, Yoshinobu Takakura Induction of Antitumor Immunity by Cell-Penetrating Peptide-Coupled Hsp70 Gene Transfer to Tumor Cells Induction of Antitumor Immunity by Cell-Penetrating Peptide-Coupled Hsp70 Gene Transfer to Tumor Cells Induction of Antitumor Immunity by Cell-Penetrating Peptide-Coupled Hsp70 Gene Transfer to Tumor Cells MOLECULAR THERAPY, 13, S380-S381 MOLECULAR THERAPY, 13, S380-S381 MOLECULAR THERAPY, 13, S380-S381 2006/05 English Research paper, summary (international conference) Disclose to all
Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa, Yoshinobu Takakura Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa, Yoshinobu Takakura Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells MOLECULAR THERAPY, 13, S237-S238 MOLECULAR THERAPY, 13, S237-S238 MOLECULAR THERAPY, 13, S237-S238 2006/05 English Research paper, summary (international conference) Disclose to all
Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda, Yoshinobu Takakura Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda, Yoshinobu Takakura Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda, Yoshinobu Takakura Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression MOLECULAR THERAPY, 13, S17-S17 MOLECULAR THERAPY, 13, S17-S17 MOLECULAR THERAPY, 13, S17-S17 2006/05 English Research paper, summary (international conference) Disclose to all
M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida Chemically modified catalase for prevention of ROS-mediated injury and tumor metastasis Chemically modified catalase for prevention of ROS-mediated injury and tumor metastasis Chemically modified catalase for prevention of ROS-mediated injury and tumor metastasis FEBS JOURNAL, 272, 524-525 FEBS JOURNAL, 272, 524-525 FEBS JOURNAL, 272, 524-525 2005/07 English Research paper, summary (international conference) Disclose to all
Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Makiya Nishikawa, Yoshinobu Takakura, Mitsuru Hashida Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine Advances in Genetics, 53, 47-68 Advances in Genetics, 53, 47-68 Advances in Genetics, 53, 47-68 2005 English Book review, literature introduction, etc. Disclose to all
西川元也, 小林直樹, 高倉喜信 西川元也, 小林直樹, 高倉喜信 RNAiベクターの生体への応用 RNAiベクターの生体への応用 Mol Med, 41, 1, 22-29 Mol Med, 41, 1, 22-29 , 41, 1, 22-29 2004/01 Japanese Disclose to all
高橋有己, 西川元也, 高倉喜信 高橋有己, 西川元也, 高倉喜信 Hydrodynamics法を用いたRNAiベクターの導入法 Hydrodynamics法を用いたRNAiベクターの導入法 改訂RNAi実験プロトコール, 0, 173-178 改訂RNAi実験プロトコール, 0, 173-178 , 0, 173-178 2004/01 Japanese Disclose to all
西川元也, 小林直樹, 高倉喜信 西川元也, 小林直樹, 高倉喜信 siRNA・siRNA発現ベクターデリバリーシステム siRNA・siRNA発現ベクターデリバリーシステム 遺伝子医学, 7, 3, 361-365 遺伝子医学, 7, 3, 361-365 , 7, 3, 361-365 2003/09 Japanese Disclose to all
M Nishikawa, T Kuramoto, T Okabe, Y Takakura, M Hashida M Nishikawa, T Kuramoto, T Okabe, Y Takakura, M Hashida M Nishikawa, T Kuramoto, T Okabe, Y Takakura, M Hashida Utilization of biological response against nonviral vectors for enhancing transgene expression Utilization of biological response against nonviral vectors for enhancing transgene expression Utilization of biological response against nonviral vectors for enhancing transgene expression MOLECULAR THERAPY, 7, 5, S167-S167 MOLECULAR THERAPY, 7, 5, S167-S167 MOLECULAR THERAPY, 7, 5, S167-S167 2003/05 English Research paper, summary (international conference) Disclose to all
A Kawase, K Isaji, N Kobayashi, M Nishikawa, Y Takakura A Kawase, K Isaji, N Kobayashi, M Nishikawa, Y Takakura A Kawase, K Isaji, N Kobayashi, M Nishikawa, Y Takakura Manipulation of immune responses by DNA vaccination through controlled local pharmacokinetics of DNA by complex formation with cationic macromolecule Manipulation of immune responses by DNA vaccination through controlled local pharmacokinetics of DNA by complex formation with cationic macromolecule Manipulation of immune responses by DNA vaccination through controlled local pharmacokinetics of DNA by complex formation with cationic macromolecule MOLECULAR THERAPY, 7, 5, S267-S267 MOLECULAR THERAPY, 7, 5, S267-S267 MOLECULAR THERAPY, 7, 5, S267-S267 2003/05 English Research paper, summary (international conference) Disclose to all
F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida F Sakurai, R Inoue, Y Nishino, A Okuda, O Matsumoto, T Taga, F Yamashita, Y Takakura, M Hashida Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (vol 66, pg 255, 2000) Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (vol 66, pg 255, 2000) Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (vol 66, pg 255, 2000) JOURNAL OF CONTROLLED RELEASE, 69, 1, 219-220 JOURNAL OF CONTROLLED RELEASE, 69, 1, 219-220 JOURNAL OF CONTROLLED RELEASE, 69, 1, 219-220 2000/10 English Other Disclose to all
M. Hashida, M. Nishikawa, F. Yamashita, Y. Takakura M. Hashida, M. Nishikawa, F. Yamashita, Y. Takakura M. Hashida, M. Nishikawa, F. Yamashita, Y. Takakura Cell-specific targeting of drugs and genes with glycosylated liposomes: Comparison with glycosylated poly(amino acids) Cell-specific targeting of drugs and genes with glycosylated liposomes: Comparison with glycosylated poly(amino acids) Cell-specific targeting of drugs and genes with glycosylated liposomes: Comparison with glycosylated poly(amino acids) ACS Symposium Series, 752, 201-211 ACS Symposium Series, 752, 201-211 ACS Symposium Series, 752, 201-211 2000 Refereed English Disclose to all
H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida Development of a macromolecular prodrug of FK506: I. Synthesis of FK506-dextran conjugate Development of a macromolecular prodrug of FK506: I. Synthesis of FK506-dextran conjugate Development of a macromolecular prodrug of FK506: I. Synthesis of FK506-dextran conjugate TRANSPLANTATION PROCEEDINGS, 30, 7, 3598-3599 TRANSPLANTATION PROCEEDINGS, 30, 7, 3598-3599 TRANSPLANTATION PROCEEDINGS, 30, 7, 3598-3599 1998/11 Refereed English Disclose to all
H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida H Yura, N Yoshimura, T Hamashima, T Oka, Y Takakura, M Hashida Development of a macromolecular prodrug of FK 506: II: In vitro study for FK 506 dextran conjugate Development of a macromolecular prodrug of FK 506: II: In vitro study for FK 506 dextran conjugate Development of a macromolecular prodrug of FK 506: II: In vitro study for FK 506 dextran conjugate TRANSPLANTATION PROCEEDINGS, 30, 4, 1031-1032 TRANSPLANTATION PROCEEDINGS, 30, 4, 1031-1032 TRANSPLANTATION PROCEEDINGS, 30, 4, 1031-1032 1998/06 Refereed English Disclose to all
N Yoshimura, H Yura, T Hamashima, T Oka, Y Takakura, M Hadhida N Yoshimura, H Yura, T Hamashima, T Oka, Y Takakura, M Hadhida N Yoshimura, H Yura, T Hamashima, T Oka, Y Takakura, M Hadhida Development of a macromolecular prodrug of FK 506: III: In vivo disposition of FK 506 dextran conjugate Development of a macromolecular prodrug of FK 506: III: In vivo disposition of FK 506 dextran conjugate Development of a macromolecular prodrug of FK 506: III: In vivo disposition of FK 506 dextran conjugate TRANSPLANTATION PROCEEDINGS, 30, 4, 1029-1030 TRANSPLANTATION PROCEEDINGS, 30, 4, 1029-1030 TRANSPLANTATION PROCEEDINGS, 30, 4, 1029-1030 1998/06 Refereed English Disclose to all
高木敏英, 橋口美和, 高倉喜信, 橋田充, 土井健史, 今西武, 鈴木宏志, 児玉龍彦 高木敏英, 橋口美和, 高倉喜信, 橋田充, 土井健史, 今西武, 鈴木宏志, 児玉龍彦 高木敏英, 橋口美和, 高倉喜信, 橋田充, 土井健史, 今西武, 鈴木宏志, 児玉龍彦 Incorporating mechanism of plasmid DNA in macrophage. Is the class A scavenger receptor involved ? マクロファージにおけるプラスミドDNAの取り込み機構 クラスAスカベンジャー受容体は関与するか? Incorporating mechanism of plasmid DNA in macrophage. Is the class A scavenger receptor involved ? 日本薬学会年会要旨集, 118th, 4, 37 日本薬学会年会要旨集, 118th, 4, 37 日本薬学会年会要旨集, 118th, 4, 37 1998/03 Japanese Disclose to all
M. Nishikawa, P. Opanasopit, K. Shiraishi, Y. Takakura, M. Hashida M. Nishikawa, P. Opanasopit, K. Shiraishi, Y. Takakura, M. Hashida M. Nishikawa, P. Opanasopit, K. Shiraishi, Y. Takakura, M. Hashida Pharmacokinetic analysis of mannose receptor-mediated hepatic targeting of proteins: Capacity-limited hepatic uptake and saturable binding in plasma Pharmacokinetic analysis of mannose receptor-mediated hepatic targeting of proteins: Capacity-limited hepatic uptake and saturable binding in plasma Pharmacokinetic analysis of mannose receptor-mediated hepatic targeting of proteins: Capacity-limited hepatic uptake and saturable binding in plasma Proceedings of the Controlled Release Society, 25, 506-507 Proceedings of the Controlled Release Society, 25, 506-507 Proceedings of the Controlled Release Society, 25, 506-507 1998 Refereed English Disclose to all
RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida RI Mahato, Y Takakura, M Hashida Disposition and gene expression of plasmid DNA complexed with cationic carriers Disposition and gene expression of plasmid DNA complexed with cationic carriers Disposition and gene expression of plasmid DNA complexed with cationic carriers 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 265-266 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 265-266 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 265-266 1996 Refereed English Disclose to all
Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Y Yabe, Y Koyama, M Nishikawa, Y Takakura, M Hashida Control of disposition characteristics of catalase by chemical modification Control of disposition characteristics of catalase by chemical modification Control of disposition characteristics of catalase by chemical modification 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 649-650 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 649-650 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 649-650 1996 Refereed English Disclose to all
M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida M Nishikawa, Y Takakura, M Hashida Pharmacokinetic evaluation of the in vivo disposition characteristics of protein drugs radiolabeled by different methods Pharmacokinetic evaluation of the in vivo disposition characteristics of protein drugs radiolabeled by different methods Pharmacokinetic evaluation of the in vivo disposition characteristics of protein drugs radiolabeled by different methods 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 875-876 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 875-876 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 875-876 1996 Refereed English Disclose to all
T Nomura, Y Takakura, M Hashida T Nomura, Y Takakura, M Hashida T Nomura, Y Takakura, M Hashida In vivo gene expression following direct injection of naked plasmid DNA into tumor In vivo gene expression following direct injection of naked plasmid DNA into tumor In vivo gene expression following direct injection of naked plasmid DNA into tumor 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 909-910 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 909-910 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 909-910 1996 Refereed English Disclose to all
Y Oka, Y Takakura, M Hashida Y Oka, Y Takakura, M Hashida Y Oka, Y Takakura, M Hashida Renal disposition characteristics of unmodified and phosphorothioated antisense oligonucleotides in situ and in vitro Renal disposition characteristics of unmodified and phosphorothioated antisense oligonucleotides in situ and in vitro Renal disposition characteristics of unmodified and phosphorothioated antisense oligonucleotides in situ and in vitro 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 907-908 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 907-908 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 907-908 1996 Refereed English Disclose to all
S Takemura, M Nishikawa, Y Takakura, M Hashida S Takemura, M Nishikawa, Y Takakura, M Hashida S Takemura, M Nishikawa, Y Takakura, M Hashida Pharmacokinetic analysis of hepatocyte-specific targeting of plasmid DNA using galactosylated poly-L-lysine Pharmacokinetic analysis of hepatocyte-specific targeting of plasmid DNA using galactosylated poly-L-lysine Pharmacokinetic analysis of hepatocyte-specific targeting of plasmid DNA using galactosylated poly-L-lysine 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 901-902 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 901-902 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 901-902 1996 Refereed English Disclose to all
H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida H Bando, M Sahashi, F Yamashita, Y Takakura, M Hashida Analysis of in vivo skin penetration enhancement by prodrug-enhancer combination based on a diffusion/bioconversion model Analysis of in vivo skin penetration enhancement by prodrug-enhancer combination based on a diffusion/bioconversion model Analysis of in vivo skin penetration enhancement by prodrug-enhancer combination based on a diffusion/bioconversion model 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 277-278 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 277-278 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 277-278 1996 Refereed English Disclose to all
H Masuda, Y Takakura, M Hashida H Masuda, Y Takakura, M Hashida H Masuda, Y Takakura, M Hashida Pharmacokinetics and hepatic uptake mechanism of recombinant rat decorin after intravenous injection in mice Pharmacokinetics and hepatic uptake mechanism of recombinant rat decorin after intravenous injection in mice Pharmacokinetics and hepatic uptake mechanism of recombinant rat decorin after intravenous injection in mice 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 669-670 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 669-670 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 669-670 1996 Refereed English Disclose to all
T Takagi, T Kanamaru, Y Takakura, M Hashida T Takagi, T Kanamaru, Y Takakura, M Hashida T Takagi, T Kanamaru, Y Takakura, M Hashida Biological activity and intracellular pharmacokinetics of antisense oligonucleotides: Effect of cationic liposomes Biological activity and intracellular pharmacokinetics of antisense oligonucleotides: Effect of cationic liposomes Biological activity and intracellular pharmacokinetics of antisense oligonucleotides: Effect of cationic liposomes 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 905-906 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 905-906 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 905-906 1996 Refereed English Disclose to all
K Ogawara, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Nishikawa, Y Takakura, M Hashida K Ogawara, M Nishikawa, Y Takakura, M Hashida Hepatic disposition characteristics of glycosylated bovine serum albumin in rats Hepatic disposition characteristics of glycosylated bovine serum albumin in rats Hepatic disposition characteristics of glycosylated bovine serum albumin in rats 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 665-666 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 665-666 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 665-666 1996 Refereed English Disclose to all
K Kawabata, Y Watanabe, Y Takakura, M Hashida K Kawabata, Y Watanabe, Y Takakura, M Hashida K Kawabata, Y Watanabe, Y Takakura, M Hashida Interferon gene transfer into intestinal epithelial cells Interferon gene transfer into intestinal epithelial cells Interferon gene transfer into intestinal epithelial cells 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 891-892 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 891-892 23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 23, 891-892 1996 Refereed English Disclose to all
西川元也, 平林英樹, 高倉喜信, 橋田充 西川元也, 平林英樹, 高倉喜信, 橋田充 糖鎖認識機構を利用した細胞特異的薬物ターゲティング 糖鎖認識機構を利用した細胞特異的薬物ターゲティング PHARM TECH JAPAN, 11, 395-403 PHARM TECH JAPAN, 11, 395-403 , 11, 395-403 1995/01 Japanese Disclose to all
M. Nishikawa, F. Yamashita, Y. Takakura, M. Hashida M. Nishikawa, F. Yamashita, Y. Takakura, M. Hashida M. Nishikawa, F. Yamashita, Y. Takakura, M. Hashida Molecular design of protein derivatives targeted to the liver via the asialoglycoprotein receptor Molecular design of protein derivatives targeted to the liver via the asialoglycoprotein receptor Molecular design of protein derivatives targeted to the liver via the asialoglycoprotein receptor Proceedings of the Controlled Release Society, 22, 502-503 Proceedings of the Controlled Release Society, 22, 502-503 Proceedings of the Controlled Release Society, 22, 502-503 1995 Refereed English Disclose to all
T. Nomura, F. Yamashita, Y. Takakura, N. Hashida T. Nomura, F. Yamashita, Y. Takakura, N. Hashida T. Nomura, F. Yamashita, Y. Takakura, N. Hashida Pharmacokinetic analysis of various lipid carrier systems after intratumoral injection in tissue-isolated tumors Pharmacokinetic analysis of various lipid carrier systems after intratumoral injection in tissue-isolated tumors Pharmacokinetic analysis of various lipid carrier systems after intratumoral injection in tissue-isolated tumors Proceedings of the Controlled Release Society, 22, 420-421 Proceedings of the Controlled Release Society, 22, 420-421 Proceedings of the Controlled Release Society, 22, 420-421 1995 Refereed English Disclose to all
Y. Takakura, T. Takagi, S. Masuda, M. Hashida Y. Takakura, T. Takagi, S. Masuda, M. Hashida Y. Takakura, T. Takagi, S. Masuda, M. Hashida Targeted delivery of superoxide dismutase to macrophages by direct cationization Targeted delivery of superoxide dismutase to macrophages by direct cationization Targeted delivery of superoxide dismutase to macrophages by direct cationization Proceedings of the Controlled Release Society, 22, 500-501 Proceedings of the Controlled Release Society, 22, 500-501 Proceedings of the Controlled Release Society, 22, 500-501 1995 Refereed English Disclose to all
H BANDO, F YAMASHITA, Y TAKAKURA, M HASHIDA H BANDO, F YAMASHITA, Y TAKAKURA, M HASHIDA H BANDO, F YAMASHITA, Y TAKAKURA, M HASHIDA SKIN PENETRATION ENHANCEMENT OF ACYCLOVIR BY PRODRUG-ENHANCER COMBINATION SKIN PENETRATION ENHANCEMENT OF ACYCLOVIR BY PRODRUG-ENHANCER COMBINATION SKIN PENETRATION ENHANCEMENT OF ACYCLOVIR BY PRODRUG-ENHANCER COMBINATION BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 8, 1141-1143 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 8, 1141-1143 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 17, 8, 1141-1143 1994/08 English Article, review, commentary, editorial, etc.(scientific journal) Disclose to all
K. Kawabata, Y. Takakura, M. Hashida K. Kawabata, Y. Takakura, M. Hashida K. Kawabata, Y. Takakura, M. Hashida In vivo stability and disposition characteristics of plasmid DNA In vivo stability and disposition characteristics of plasmid DNA In vivo stability and disposition characteristics of plasmid DNA Proceedings of the Controlled Release Society, 21, 242-243 Proceedings of the Controlled Release Society, 21, 242-243 Proceedings of the Controlled Release Society, 21, 242-243 1994 Refereed English Disclose to all
H. Tokuda, S. Choksakulnimitr, S. Masuda, Y. Takakura, M. Hashida H. Tokuda, S. Choksakulnimitr, S. Masuda, Y. Takakura, M. Hashida H. Tokuda, S. Choksakulnimitr, S. Masuda, Y. Takakura, M. Hashida Uptake characteristics and cytotoxicity of plasmid DNA in cultured macrophages and endothelial cells Uptake characteristics and cytotoxicity of plasmid DNA in cultured macrophages and endothelial cells Uptake characteristics and cytotoxicity of plasmid DNA in cultured macrophages and endothelial cells Proceedings of the Controlled Release Society, 21, 244-245 Proceedings of the Controlled Release Society, 21, 244-245 Proceedings of the Controlled Release Society, 21, 244-245 1994 Refereed English Disclose to all
山下 富義, 小山 靖夫, 坂東 博人, 高倉 喜信, 橋田 充 山下 富義, 小山 靖夫, 坂東 博人, 高倉 喜信, 橋田 充 機構論に基づく吸収促進剤適用の最適化の試み 機構論に基づく吸収促進剤適用の最適化の試み Drug Delivery System, 8, 4, 243-250 Drug Delivery System, 8, 4, 243-250 , 8, 4, 243-250 1993 Disclose to all
Hisao Furitsu, Yoshinobu Takakura, Mitsuru Hashida, Takuya Fujita, Hitoshi Sezaki 振津 尚夫, 高倉 喜信, 橋田 充, 藤田 卓也, 瀬崎 仁 Hisao Furitsu, Yoshinobu Takakura, Mitsuru Hashida, Takuya Fujita, Hitoshi Sezaki Inhibitory effect of superoxide dismutase derivatives modified with various sugar moieties on ischemia/reperfusion injury 各種糖修飾superoxide dismutaseの肝障害抑制効果 Inhibitory effect of superoxide dismutase derivatives modified with various sugar moieties on ischemia/reperfusion injury Drug Delivery System, 8, 1, 49-52 Drug Delivery System, 8, 1, 49-52 Drug Delivery System, 8, 1, 49-52 1993 English Disclose to all
Kiyoshi Mihara, Mihoko Mori, Takami Hojo, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Kiyoshi Mihara, Mihoko Mori, Takami Hojo, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Kiyoshi Mihara, Mihoko Mori, Takami Hojo, Yoshinobu Takakura, Mitsuru Hashida, Hitoshi Sezaki Disposition Characteristics of Model Macromolecules in the Perfused Rat Kidney Disposition Characteristics of Model Macromolecules in the Perfused Rat Kidney Disposition Characteristics of Model Macromolecules in the Perfused Rat Kidney Biological and Pharmaceutical Bulletin, 16, 2, 158-162 Biological and Pharmaceutical Bulletin, 16, 2, 158-162 Biological and Pharmaceutical Bulletin, 16, 2, 158-162 1993 English Disclose to all
H. Tokuda, Y. Takakura, M. Hashida H. Tokuda, Y. Takakura, M. Hashida H. Tokuda, Y. Takakura, M. Hashida Targeted delivery of polyanions to the brain Targeted delivery of polyanions to the brain Targeted delivery of polyanions to the brain Proceedings of the Controlled Release Society, 20, 270-271 Proceedings of the Controlled Release Society, 20, 270-271 Proceedings of the Controlled Release Society, 20, 270-271 1993 Refereed English Disclose to all
T. Miyao, Y. Takakura, M. Hashida T. Miyao, Y. Takakura, M. Hashida T. Miyao, Y. Takakura, M. Hashida Stability and in vivo disposition characteristics of oligonucleotides and oligonucleotide conjugated with macromolecule Stability and in vivo disposition characteristics of oligonucleotides and oligonucleotide conjugated with macromolecule Stability and in vivo disposition characteristics of oligonucleotides and oligonucleotide conjugated with macromolecule Proceedings of the Controlled Release Society, 20, 492-493 Proceedings of the Controlled Release Society, 20, 492-493 Proceedings of the Controlled Release Society, 20, 492-493 1993 Refereed English Disclose to all
F. Yamashita, Y. Koyama, Y. Takakura, M. Hashida F. Yamashita, Y. Koyama, Y. Takakura, M. Hashida F. Yamashita, Y. Koyama, Y. Takakura, M. Hashida Comparison of action mechanism of penetration enhancers based on a skin diffusion model Comparison of action mechanism of penetration enhancers based on a skin diffusion model Comparison of action mechanism of penetration enhancers based on a skin diffusion model Proceedings of the Controlled Release Society, 20, 424-425 Proceedings of the Controlled Release Society, 20, 424-425 Proceedings of the Controlled Release Society, 20, 424-425 1993 Refereed English Disclose to all
Y TAKAKURA, M HASHIDA, H SEZAKI Y TAKAKURA, M HASHIDA, H SEZAKI Y TAKAKURA, M HASHIDA, H SEZAKI MECHANISM OF HEPATIC-UPTAKE OF POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE MECHANISM OF HEPATIC-UPTAKE OF POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE MECHANISM OF HEPATIC-UPTAKE OF POLYMERIC PRODRUG OF MITOMYCIN-C, MITOMYCIN-C-DEXTRAN CONJUGATE JOURNAL OF PHARMACEUTICAL SCIENCES, 76, 11, S98-S98 JOURNAL OF PHARMACEUTICAL SCIENCES, 76, 11, S98-S98 JOURNAL OF PHARMACEUTICAL SCIENCES, 76, 11, S98-S98 1987/11 English Research paper, summary (international conference) Disclose to all
Y TAKAKURA, M HASHIDA, H SEZAKI Y TAKAKURA, M HASHIDA, H SEZAKI Y TAKAKURA, M HASHIDA, H SEZAKI ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C BY POLYMERIC MODIFICATION ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C BY POLYMERIC MODIFICATION ENHANCED LYMPHATIC DELIVERY OF MITOMYCIN-C BY POLYMERIC MODIFICATION JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 4, S63-S63 JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 4, S63-S63 JOURNAL OF PHARMACOBIO-DYNAMICS, 7, 4, S63-S63 1984 English Research paper, summary (international conference) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Diagnostic and Therapeutic Applications of Exosomes in Cance Diagnostic and Therapeutic Applications of Exosomes in Cance Diagnostic and Therapeutic Applications of Exosomes in Cance Elsevier Elsevier Elsevier 2018 English Contributor Disclose to all
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Extracellular Vesicles Extracellular Vesicles Extracellular Vesicles Wiley Wiley Wiley 2017 English Contributor Disclose to all
高倉 喜信 高倉 喜信 飛躍するDDSサイエンス 飛躍するDDSサイエンス Drug Delivery System, Drug Delivery System, 2017 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 医療薬学 Ⅳ. 薬理・病態・薬物治療(4)(スタンダード薬学シリーズⅡ6) 医療薬学 Ⅳ. 薬理・病態・薬物治療(4)(スタンダード薬学シリーズⅡ6) 東京化学同人 東京化学同人 2017 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 パラダイムシフトをもたらすエクソソーム機能研究最前線 パラダイムシフトをもたらすエクソソーム機能研究最前線 NTS NTS 2017 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 くすりをつくる研究者の仕事 くすりをつくる研究者の仕事 化学同人 化学同人 2017 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 DDS 最近の進歩 DDS 最近の進歩 ファルマシア ファルマシア 2016 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 エクソソームを利用したDDSの開発 エクソソームを利用したDDSの開発 実験医学, 実験医学, 2016 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 さらなるDDSの発展を目指して さらなるDDSの発展を目指して Drug Delivery System Drug Delivery System 2016 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 バイオマテリアル:その基礎と先端研究への展開 バイオマテリアル:その基礎と先端研究への展開 東京化学同人 東京化学同人 2016 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 核酸医薬の創製と応用展開 核酸医薬の創製と応用展開 シーエムシー シーエムシー 2016 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 核酸医薬のためのデリバリー技術 核酸医薬のためのデリバリー技術 日本核酸医薬学会会誌 日本核酸医薬学会会誌 2015 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 ドラッグデリバリーシステムとしてのエキソソーム ドラッグデリバリーシステムとしてのエキソソーム 細胞 細胞 2015 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 ハイドロダイナミクス法:高効率なin vivo遺伝子導入法 ハイドロダイナミクス法:高効率なin vivo遺伝子導入法 実験医学 実験医学 2015 Japanese Other Disclose to all
高倉喜信 高倉喜信 薬剤学慨史-私はこう見る 120人による俯瞰図 薬剤学慨史-私はこう見る 120人による俯瞰図 日本薬剤学会 日本薬剤学会 2015 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 核酸医薬のための次世代DDS開発 核酸医薬のための次世代DDS開発 ファームテクジャパン ファームテクジャパン 2015 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 発刊によせて 発刊によせて ファームテクジャパン ファームテクジャパン 2015 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 新薬展望2015 第1部 新薬創出における日本医療研究開発機構(AMED)の役割 新薬展望2015 第1部 新薬創出における日本医療研究開発機構(AMED)の役割 医薬ジャーナル 医薬ジャーナル 2015 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 10年後、20年後、そしてさらなる未来に向けて 10年後、20年後、そしてさらなる未来に向けて Drug Delivery System Drug Delivery System 2015 Japanese Other Disclose to all
高倉喜信 高倉喜信 薬剤学実験法必携マニュアル―(分担執筆) 薬剤学実験法必携マニュアル―(分担執筆) 南江堂 南江堂 2014/04 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 オリゴ核酸を基盤とする多足型核酸構造体を利用した免疫刺激性核酸デリバリーシステムの開発 オリゴ核酸を基盤とする多足型核酸構造体を利用した免疫刺激性核酸デリバリーシステムの開発 Antisense Antisense 2014 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 バイオ薬医の動態制御 バイオ薬医の動態制御 薬剤学 薬剤学 2014 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 30周年を迎えて 30周年を迎えて Drug Delivery System Drug Delivery System 2014 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 細胞スフェロイド化技術の開発と細胞治療への応用 細胞スフェロイド化技術の開発と細胞治療への応用 Drug Delivery System Drug Delivery System 2014 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 細胞治療とDDS-細胞を制御する、細胞で制御するー 細胞治療とDDS-細胞を制御する、細胞で制御するー Drug Delivery System Drug Delivery System 2013 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 日本のプレセンスを! 日本のプレセンスを! Drug Delivery System Drug Delivery System 2013 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 応用が拡がるDDSー人体環境から農業・家電までー(分担執筆) 応用が拡がるDDSー人体環境から農業・家電までー(分担執筆) NTS NTS 2013 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 遺伝子・細胞製剤フォーカスグループの活動について 遺伝子・細胞製剤フォーカスグループの活動について 薬剤学 薬剤学 2012 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 RNA干渉を利用した疾患治療システム RNA干渉を利用した疾患治療システム 生体の科学 生体の科学 2012 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 薬剤学研究の将来ー薬学教育6年制導入から6年ー 薬剤学研究の将来ー薬学教育6年制導入から6年ー 薬剤学 薬剤学 2012 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 昇り竜のごとく 昇り竜のごとく Drug Delivery System Drug Delivery System 2012 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 新しい薬学事典(分担執筆) 新しい薬学事典(分担執筆) 朝倉書店 朝倉書店 2012 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 DDSのさらなる発展のために DDSのさらなる発展のために Drug Delivery System Drug Delivery System 2011 Japanese Other Disclose to all
高倉 喜信 高倉 喜信 次世代バイオ医薬品の製剤設計と開発戦略(分担執筆) 次世代バイオ医薬品の製剤設計と開発戦略(分担執筆) シーエムーシ シーエムーシ 2011 Japanese Contributor Disclose to all
高倉 喜信 高倉 喜信 アジュバンド開発研究の新展開(分担執筆) アジュバンド開発研究の新展開(分担執筆) シーエム-シー シーエム-シー 2011 Japanese Contributor Disclose to all
高倉喜信, 橋田 充, 京, 高倉喜信, 学研究 高倉喜信, 橋田 充, 京, 高倉喜信, 学研究 図解で学ぶDDS―薬物治療の最適化を目指す先端創薬技術(編集) 図解で学ぶDDS―薬物治療の最適化を目指す先端創薬技術(編集) じほう じほう 2010/08 Japanese Disclose to all
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development, Informa Healthcare Informa Healthcare Informa Healthcare 2009 English Contributor Disclose to all
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Polymeric Gene Delivery Principles and Applications Polymeric Gene Delivery Principles and Applications Polymeric Gene Delivery Principles and Applications CRC Press CRC Press CRC Press 2005 English Contributor Disclose to all
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Drug Delivery: Principles and Applications Drug Delivery: Principles and Applications Drug Delivery: Principles and Applications Wiley Wiley Wiley 2005 English Contributor Disclose to all
TAKAKURA Yoshinobu 高倉 喜信 TAKAKURA Yoshinobu Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics Taylor & Francis Taylor & Francis 2002 English Contributor Disclose to all
橋田 充, 高倉 喜信 橋田 充, 高倉 喜信 生体内薬物送達学 (基礎生体工学講座)(共著) 生体内薬物送達学 (基礎生体工学講座)(共著) 産業図書 産業図書 1994/10 Japanese Joint Work Disclose to all
髙倉 喜信 髙倉 喜信 バイオコンジュゲート医薬品(分担執筆) バイオコンジュゲート医薬品(分担執筆) 廣川書店, 廣川書店, 1993 Japanese Disclose to all

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Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
日本薬物動態学会奨励賞 1995
日本薬学会奨励賞 1996
AAPSフェロー 2009
タケル・アヤ・ヒグチ記念賞 2011
日本薬剤学会賞 2019/05/
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
基盤研究(B) Representative 機能改変タンパク質および核酸を基盤とした包括的抗腫瘍免疫治療システムの開発  2007-2008
萌芽研究 Representative 抗原投与を全く必要としない細胞内抗原トラップ型新規腫瘍ワクチンの開発 2007-2008/__/__
挑戦的萌芽研究 Representative 遺伝子発現再活性化現象を利用したリピータブルタンパク質発現システムの開発 2009-2009
特定領域研究 Representative インターフェロン遺伝子発現の増強・持続化による新規癌治療戦略 2008-2009
厚生労働科学研究費 Assignment ヒト肝細胞キメラマウスを用いた治療抵抗性の肝炎に関する研究  2008-2010
基盤研究(B) Representative 治療用タンパク・siRNA発現の時空間制御のためのプラスミドデザインとデリバリー 2009-2011
挑戦的萌芽研究 Representative 一回の投与で繰り返しタンパク質を供給可能なオンデマンド型遺伝子治療システムの開発 2010-2010
厚生労働科学研究費 Assignment 創薬と新規治療法に開発に資するヒト肝細胞キメラマウスを用いた肝炎ウィルス制御に関する研究 2011-2013
基盤研究(B) Assignment 多足型構造を形成する核酸を基盤とする核酸ナノDDS開発 2011-2015/03/31
挑戦的萌芽研究 Assignment 細胞個性に立脚したターゲティング型細胞治療システムの開発 2011-2012
基盤研究(B) Representative 転写・翻訳/体内動態/細胞応答の三元制御に基づくサイトカイン遺伝子治療の最適化  2012-2014
基盤研究(B) Representative 転写・翻訳/体内動態/細胞応答の三元制御に基づくサイトカイン遺伝(平成26年度) 2014-2015
挑戦的萌芽研究 Assignment RNA医薬を搭載した標的指向型多機能性エキソソームの開発 2012-2013
挑戦的萌芽研究 Assignment 混合型細胞スフェロイド化技術を駆使した高機能微小組織移植治療システムの開発 2013-2013
挑戦的萌芽研究 Representative 自己粒子化RNAスポンジを利用した免疫療法用DDS開発 2014/04/01-2016/03/31
挑戦的萌芽研究 Assignment エキソソーム指向性siRNA誘導体の設計による生体内RNA干渉の効率的誘導 2014-2015
基盤研究(B) Assignment 3次元構ナノDNA造体を基本ユニットとする疾患治療システムの開発(平成26・27年度分) 2014-
基盤研究(B) Representative 遺伝子発現と生体応答の包括的制御による治療係数の高いサイトカン遺伝子治療法開発 2015-
基盤研究(B) Representative 遺伝子発現と生体応答の包括的制御による治療係数の高いサイトカイン遺伝子治療法開発 (平成27年度分) 2015/04/01-2016/03/31
挑戦的萌芽研究 Representative 自己粒子化RNAスポンジを利用した免疫療法用DDS開発 (平成27年度分) 2015/04/01-2016/03/31
基盤研究(B) Representative 遺伝子発現と生体応答の包括的制御による治療係数の高いサイトカイン遺伝子治療法開発 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(B) Representative 遺伝子発現と生体応答の包括的制御による治療係数の高いサイトカイン遺伝子治療法開発 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(B) Representative 免疫制御分子搭載エキソソームを利用したin vivo 遺伝子治療法の開発 (平成30年度分) 2018/04/01-2019/03/31
基盤研究(B) Representative 免疫制御分子搭載エキソソームを利用したin vivo 遺伝子治療法の開発 (2019年度分) 2019/04/01-2020/03/31
基盤研究(B) Representative 免疫制御分子搭載エキソソームを利用したin vivo 遺伝子治療法の開発 (2020年度分) 2020/04/01-2021/03/31

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External funds: other than those above
System Main person Title(Japanese) Title(English) Period
細胞特異的薬物送達に関する研究 Study on Cell Specific Drug Delivery -
遺伝子治療における製剤設計に関する研究 Study on Dosage Form Design for Gene Therapy -
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
医療実務事前学習 後期前期 薬学部 2011/04-2012/03
医療薬学III(薬物動態学) 後期 薬学部 2011/04-2012/03
特別実習(病態情報薬学) 通年 薬学部 2011/04-2012/03
薬剤学3(薬物動態学) 後期 薬学部 2011/04-2012/03
医薬品開発プロジェクト演習I 前期 薬学部 2011/04-2012/03
統合型薬学演習 後期 薬学部 2011/04-2012/03
特別実習[病態情報薬学] 通年 薬学部 2011/04-2012/03
薬局実務実習 通年 薬学部 2011/04-2012/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2011/04-2012/03
病態情報薬学実験 Research in Biopharmaceutics and Drug Metabolism 通年不定 薬学研究科 2011/04-2012/03
病態機能解析学実習 Advanced Methods in Pharmacodynamic Sciences 通年不定 薬学研究科 2011/04-2012/03
病態情報薬学演習 Biopharmaceutics and Drug Metabolism Seminar 通年不定 薬学研究科 2011/04-2012/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2011/04-2012/03
先端医療SGD演習 前期 薬学部 2011/04-2012/03
共用試験関係 通年 薬学部 2011/04-2012/03
医療倫理実習 後期 薬学部 2011/04-2012/03
地域医療薬学 前期 薬学部 2011/04-2012/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and 前期不定 薬学研究科 2011/04-2012/03
基盤医療薬科学実験技術(秋入学用) Basic Laboratory Techniques in Pharmacy and 後期不定 薬学研究科 2011/04-2012/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2011/04-2012/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2011/04-2012/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2011/04-2012/03
病院実務実習 通年 薬学部 2011/04-2012/03
臨床薬学総論 後期 薬学部 2011/04-2012/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2011/04-2012/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2012/04-2013/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2012/04-2013/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2012/04-2013/03
医療薬学III(薬物動態学) Medicinal Pharmacy III(Biopharmaceutics) 後期 薬学部 2012/04-2013/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2012/04-2013/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2012/04-2013/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2012/04-2013/03
地域医療薬学 Community Clinical Pharmacy 前期 薬学部 2012/04-2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2012/04-2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2012/04-2013/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2012/04-2013/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2012/04-2013/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2012/04-2013/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2012/04-2013/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2012/04-2013/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2012/04-2013/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2012/04-2013/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2012/04-2013/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2012/04-2013/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2012/04-2013/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2012/04-2013/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2012/04-2013/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2012/04-2013/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2012/04-2013/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2012/04-2013/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2012/04-2013/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2012/04-2013/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2012/04-2013/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2012/04-2013/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2013/04-2014/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2013/04-2014/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2013/04-2014/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2013/04-2014/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2013/04-2014/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2013/04-2014/03
地域医療薬学 Community Clinical Pharmacy 前期 薬学部 2013/04-2014/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2013/04-2014/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2013/04-2014/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2013/04-2014/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2013/04-2014/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2013/04-2014/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2013/04-2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2013/04-2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2013/04-2014/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2013/04-2014/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2013/04-2014/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2013/04-2014/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2013/04-2014/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2013/04-2014/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2013/04-2014/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2013/04-2014/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2013/04-2014/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2013/04-2014/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2013/04-2014/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2013/04-2014/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2013/04-2014/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2013/04-2014/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2014/04-2015/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2014/04-2015/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2014/04-2015/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2014/04-2015/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2014/04-2015/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2014/04-2015/03
地域医療薬学 Community Clinical Pharmacy 前期 薬学部 2014/04-2015/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2014/04-2015/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2014/04-2015/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2014/04-2015/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2014/04-2015/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2014/04-2015/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2014/04-2015/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2014/04-2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2014/04-2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2014/04-2015/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2014/04-2015/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2014/04-2015/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 後期前期 薬学研究科 2014/04-2015/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2014/04-2015/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 後期前期 薬学研究科 2014/04-2015/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2014/04-2015/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 後期前期 薬学研究科 2014/04-2015/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2014/04-2015/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2014/04-2015/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2014/04-2015/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2014/04-2015/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2014/04-2015/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2014/04-2015/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2014/04-2015/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2014/04-2015/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2015/04-2016/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2015/04-2016/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2015/04-2016/03
地域医療薬学 Community Clinical Pharmacy 前期 薬学部 2015/04-2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2015/04-2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2015/04-2016/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2015/04-2016/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 後期前期 薬学研究科 2015/04-2016/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2015/04-2016/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 後期前期 薬学研究科 2015/04-2016/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2015/04-2016/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 後期前期 薬学研究科 2015/04-2016/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2015/04-2016/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2015/04-2016/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2015/04-2016/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2015/04-2016/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2015/04-2016/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2015/04-2016/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2015/04-2016/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2015/04-2016/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2015/04-2016/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2015/04-2016/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2015/04-2016/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2015/04-2016/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2015/04-2016/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2015/04-2016/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2015/04-2016/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2015/04-2016/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2015/04-2016/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2016/04-2017/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2016/04-2017/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2016/04-2017/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2016/04-2017/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2016/04-2017/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2016/04-2017/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2016/04-2017/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2016/04-2017/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2016/04-2017/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2016/04-2017/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2016/04-2017/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2016/04-2017/03
特別実習[臨床薬学教育] Research Training(Clinical Pharmacy and Education) 通年 薬学部 2016/04-2017/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2016/04-2017/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2016/04-2017/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2016/04-2017/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2016/04-2017/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2016/04-2017/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2016/04-2017/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2016/04-2017/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2016/04-2017/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2016/04-2017/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2016/04-2017/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2016/04-2017/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2016/04-2017/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2016/04-2017/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2016/04-2017/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2017/04-2018/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2017/04-2018/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2017/04-2018/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2017/04-2018/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2017/04-2018/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2017/04-2018/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2017/04-2018/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2017/04-2018/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2017/04-2018/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2017/04-2018/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2017/04-2018/03
統合科学 Interdisciplinary Sciences 後期 全学共通科目 2017/04-2018/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2017/04-2018/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2017/04-2018/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2017/04-2018/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2017/04-2018/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2017/04-2018/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2017/04-2018/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2017/04-2018/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2017/04-2018/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2017/04-2018/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2017/04-2018/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2017/04-2018/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2017/04-2018/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2017/04-2018/03
共用試験関係 通年 薬学部 2018/04-2019/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2018/04-2019/03
創薬リード探索理論 Bioinformatics II: Lead Discovery 前期不定 薬学研究科 2018/04-2019/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
創薬物理化学概論 Introduction to Physical Chemistry for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2018/04-2019/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2018/04-2019/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2018/04-2019/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2018/04-2019/03
基盤有機化学特論II Advanced Basic Organic Chemistry II 後期不定 薬学研究科 2018/04-2019/03
基盤物理化学特論I Advanced Basic Physical Chemistry I 前期不定 薬学研究科 2018/04-2019/03
基盤生物化学特論II Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2018/04-2019/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2018/04-2019/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2018/04-2019/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2018/04-2019/03
実務実習 通年 薬学部 2018/04-2019/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2018/04-2019/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2018/04-2019/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2018/04-2019/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2018/04-2019/03
統合科学 Interdisciplinary Sciences 後期 全学共通科目 2018/04-2019/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2018/04-2019/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2018/04-2019/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2018/04-2019/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2018/04-2019/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2018/04-2019/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 後期不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 後期前期 薬学研究科 2018/04-2019/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 後期前期 薬学研究科 2018/04-2019/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2018/04-2019/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2018/04-2019/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2018/04-2019/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 後期前期 薬学研究科 2018/04-2019/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2018/04-2019/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 後期前期 薬学研究科 2018/04-2019/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2018/04-2019/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2018/04-2019/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2018/04-2019/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2018/04-2019/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2018/04-2019/03
共用試験関係 通年 薬学部 2019/04-2020/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2019/04-2020/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2019/04-2020/03
創薬物理化学概論 Introduction to Physical Chemistry for Drug Discovery 前期不定 薬学研究科 2019/04-2020/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2019/04-2020/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2019/04-2020/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2019/04-2020/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2019/04-2020/03
基盤医療薬科学特論II Advanced Basic Pharmacy and Biomedicinal Sciences II 後期不定 薬学研究科 2019/04-2020/03
基盤有機化学特論I Advanced Basic Organic Chemistry I 後期不定 薬学研究科 2019/04-2020/03
基盤物理化学特論II Advanced Basic Physical Chemistry II 前期不定 薬学研究科 2019/04-2020/03
基盤生物化学特論I Advanced Basic Biological Chemistry I 前期不定 薬学研究科 2019/04-2020/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2019/04-2020/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2019/04-2020/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2019/04-2020/03
実務実習 通年 薬学部 2019/04-2020/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2019/04-2020/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2019/04-2020/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2019/04-2020/03
統合型薬学演習 Integrated Pharmaceutical Exercise 後期 薬学部 2019/04-2020/03
統合科学 Interdisciplinary Sciences 後期 全学共通科目 2019/04-2020/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2019/04-2020/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2019/04-2020/03
臨床開発技術 Drug Discovery & Development III: Clinical Development Process 後期不定 薬学研究科 2019/04-2020/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2019/04-2020/03
薬剤学II(薬物動態学) Pharmaceutics II (Pharmacokinetics) 後期 薬学部 2019/04-2020/03
薬剤学3(薬物動態学) Medicinal Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2019/04-2020/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 後期不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 前期不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2019/04-2020/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2019/04-2020/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 後期不定 薬学研究科 2019/04-2020/03
薬学研究演習Ⅲ Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2019/04-2020/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 前期不定 薬学研究科 2019/04-2020/03
薬学研究演習Ⅱ Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2019/04-2020/03
薬学研究演習Ⅰ Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2019/04-2020/03
薬学研究特論Ⅲ Advanced Pharmaceutical Sciences III 前期不定 薬学研究科 2019/04-2020/03
薬学研究特論Ⅱ Advanced Pharmaceutical Sciences II 前期不定 薬学研究科 2019/04-2020/03
薬学研究特論Ⅰ Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2019/04-2020/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2019/04-2020/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2019/04-2020/03
共用試験関係 Pharmaceutical Common Achievement Tests 通年 薬学部 2020/04-2021/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2020/04-2021/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2020/04-2021/03
創薬リード探索理論 Bioinformatics II: Lead Discovery 前期不定 薬学研究科 2020/04-2021/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2020/04-2021/03
創薬物理化学概論 Introduction to Physical Chemistry for Drug Discovery 前期不定 薬学研究科 2020/04-2021/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2020/04-2021/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2020/04-2021/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2020/04-2021/03
基盤医療薬科学実験技術(秋入学用) Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2020/04-2021/03
基盤医療薬科学特論Ⅰ Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2020/04-2021/03
基盤有機化学特論Ⅱ Advanced Basic Organic Chemistry II 後期不定 薬学研究科 2020/04-2021/03
基盤物理化学特論Ⅰ Advanced Basic Physical Chemistry I 前期不定 薬学研究科 2020/04-2021/03
基盤生物化学特論Ⅱ Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2020/04-2021/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2020/04-2021/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2020/04-2021/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2020/04-2021/03
実務実習(病3薬2) 通年 薬学部 2020/04-2021/03
実務実習(病2薬1) 通年 薬学部 2020/04-2021/03
実務実習(病4薬3) 通年 薬学部 2020/04-2021/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2020/04-2021/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2020/04-2021/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2020/04-2021/03
統合科学:生命と社会(持続的社会・健康社会に向けた技 … Interdisciplinary Sciences :Life and Society (Collaboration of Technology, Ethics for Sustainable and Healthy Society) 後期 全学共通科目 2020/04-2021/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2020/04-2021/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2020/04-2021/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2020/04-2021/03
薬剤学II(薬物動態学)【H30以降入学者用】 Pharmaceutics II (Pharmacokinetics) 後期 薬学部 2020/04-2021/03
薬剤学3(薬物動態学) Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2020/04-2021/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2020/04-2021/03
薬学実験技術(連絡用) Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2020/04-2021/03
薬学研究実験III Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2020/04-2021/03
薬学研究実験III(秋入学用) Research in Pharmaceutical Sciences III 前期不定 薬学研究科 2020/04-2021/03
薬学研究実験II Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2020/04-2021/03
薬学研究実験II(秋入学用) Research in Pharmaceutical Sciences II 前期不定 薬学研究科 2020/04-2021/03
薬学研究実験I Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2020/04-2021/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2020/04-2021/03
薬学研究演習III Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2020/04-2021/03
薬学研究演習III(秋入学用) Seminar for Pharmaceutical Sciences III 前期不定 薬学研究科 2020/04-2021/03
薬学研究演習II Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2020/04-2021/03
薬学研究演習II(秋入学用) Seminar for Pharmaceutical Sciences II 前期不定 薬学研究科 2020/04-2021/03
薬学研究演習I Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2020/04-2021/03
薬学研究特論I Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2020/04-2021/03
薬学研究特論II Advanced Pharmaceutical Sciences II 前期不定 薬学研究科 2020/04-2021/03
薬学研究特論III Advanced Pharmaceutical Sciences III 前期不定 薬学研究科 2020/04-2021/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2020/04-2021/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2020/04-2021/03
共用試験関係 Pharmaceutical Common Achievement Tests 通年 薬学部 2021/04-2022/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2021/04-2022/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2021/04-2022/03
創薬物理化学概論 Introduction to Physical Chemistry for Drug Discovery 前期不定 薬学研究科 2021/04-2022/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2021/04-2022/03
医療実務事前学習【H30以降入学者用】 Pre-Training for Clinical Clerkship 後期 薬学部 2021/04-2022/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2021/04-2022/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2021/04-2022/03
基盤医療薬科学実験技術(秋入学用) Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2021/04-2022/03
基盤有機化学特論Ⅰ Advanced Basic Organic Chemistry I 後期不定 薬学研究科 2021/04-2022/03
基盤物理化学特論Ⅱ Advanced Basic Physical Chemistry II 前期不定 薬学研究科 2021/04-2022/03
基盤生物化学特論Ⅰ Advanced Basic Biological Chemistry I 前期不定 薬学研究科 2021/04-2022/03
基盤病態機能解析学実習 Laboratory Practice in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2021/04-2022/03
基盤病態機能解析学実験 Research in Basic Pharmacodynanic Sciences 通年不定 薬学研究科 2021/04-2022/03
基盤病態機能解析学演習 Seminar in Basic Patho-Functional Analysis 通年不定 薬学研究科 2021/04-2022/03
実務実習(薬2病3) 通年 薬学部 2021/04-2022/03
実務実習(薬1病2) 通年 薬学部 2021/04-2022/03
実務実習(薬3病4) 通年 薬学部 2021/04-2022/03
特別実習(病態情報薬学)【H30以降入学者用】 Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2021/04-2022/03
特別実習[病態情報薬学] Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2021/04-2022/03
特別実習(病態情報薬学) Research Training(Biopharmaceutics and Drug Metabolism) 通年 薬学部 2021/04-2022/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2021/04-2022/03
統合科学:生命と社会(持続的社会・健康社会に向けた技 … Interdisciplinary Sciences :Life and Society (Collaboration of Technology, Ethics for Sustainable and Healthy Society) 後期 全学共通科目 2021/04-2022/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2021/04-2022/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2021/04-2022/03
薬剤学II(薬物動態学)【H30以降入学者用】 Pharmaceutics II (Pharmacokinetics) 後期 薬学部 2021/04-2022/03
薬剤学3(薬物動態学) Pharmacy 3 (Biopharmaceutics) 後期 薬学部 2021/04-2022/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2021/04-2022/03
薬学実験技術(連絡用) Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2021/04-2022/03
薬学研究実験III Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2021/04-2022/03
薬学研究実験II Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2021/04-2022/03
薬学研究実験I Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2021/04-2022/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2021/04-2022/03
薬学研究演習III Seminar for Pharmaceutical Sciences III 通年不定 薬学研究科 2021/04-2022/03
薬学研究演習II Seminar for Pharmaceutical Sciences II 通年不定 薬学研究科 2021/04-2022/03
薬学研究演習I Seminar for Pharmaceutical Sciences I 通年不定 薬学研究科 2021/04-2022/03
薬学研究特論I Advanced Pharmaceutical Sciences I 後期不定 薬学研究科 2021/04-2022/03
薬学研究特論II Advanced Pharmaceutical Sciences II 前期不定 薬学研究科 2021/04-2022/03
薬学研究特論III Advanced Pharmaceutical Sciences III 前期不定 薬学研究科 2021/04-2022/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2021/04-2022/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2021/04-2022/03

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School management (title, position)
Title Period
京都大学教務事務電算管理運営委員会 委員 2010/04/01-2011/03/31
大学評価委員会 点検・評価実行委員会 委員 2010/04/01-
教養教育専門委員会 委員 2008/04/01-2011/03/31
教育研究評議会評議員 2010/04/01-2012/03/31
京都大学教務事務電算管理運営委員会 委員 2011/04/01-2012/03/31
大学評価委員会点検・評価実行委員会 委員 2011/04/01-2012/03/31
教職教育委員会/教職科目連絡小委員会 委員 2011/04/01-2012/03/31
評議員 2011/04/01-2013/03/31
教職教育委員会 委員 2012/01/31-2014/01/30
京都大学教職教育委員会教職科目連絡小委員会 委員 2012/04/01-2013/03/31
大学評価委員会 点検・評価実行委員会 委員 2012/04/01-2013/03/31
人権委員会 委員 2013/04/01-2015/03/31
評議員 2010/04/01-2014/03/31
京都大学財務委員会 委員 2014/04/01-2014/09/30
全学情報セキュリティ委員会 委員 2014/04/01-2016/03/31
博士課程教育リーディングプログラム運営会議 委員 2014/04/01-2016/03/31
吉田寮整備委員会委員 2014/02/05-2016/03/31
吉田寮業務実施委員会 委員 2014/04/01-2016/03/31
国際高等教育院教養・共通教育協議会 委員 2014/04/01-2016/03/31
大学評価委員会 委員 2014/04/01-2016/03/31
教育研究評議会 評議員 2014/04/01-2016/03/31
産官学連携本部運営協議会協議員 委員 2014/04/01-2016/03/31
研究科長部会 2014/04/01-2016/03/31
薬学研究科附属統合薬学教育開発センター長 2010/04/01-2011/03/31
薬学研究科 研究科長 2014/04/01-2016/03/31
薬学部 学部長 2014/04/01-2016/03/31
薬用植物園長 2014/04/01-2016/03/31
部局長会議 2014/04/01-2016/03/31
薬学研究科附属統合薬学教育開発センター長 2014/04/01-2016/03/31
薬学研究科 研究科長 2014/04/01-2016/03/31
薬学部 学部長 2014/04/01-2016/03/31
薬用植物園長 2014/04/01-2016/03/31
研究科長部会 2014/04/01-2016/03/31
部局長会議 2014/04/01-2016/03/31
京都大学産学共同実用化促進事業実施委員会 3号委員 2014/04/01-2015/09/09
産官学連携本部運営協議会 5号協議員 2014/04/01-2016/03/31
原子力研究整備委員会 委員 2014/04/01-
入学試験委員会 委員 2014/04/01-2016/03/31
京都大学博士課程教育リーディングプログラム運営会議 委員 2014/04/01-2016/03/31
京都大学研究公正の推進検討委員会 委員 2014/08/01-2015/02/28
京都大学医学研究利益相反マネジメント委員会 2号委員 2014/09/01-2016/08/31
京都大学研究公正の推進検討委員会 研究不正対応小委員会 委員長 2014/09/27-2015/02/28
財務委員会 委員 2014/10/01-2016/09/30
京都大学研究公正委員会 委員 2015/03/01-
総長選考会議 委員 委員 2015/04/01-2016/03/31
全学情報セキュリティ委員会 委員 2015/04/01-
教育活動評価委員会 委員 2015/05/01-2016/03/31
人事制度検討会 委員 2015/04/01-2016/03/31
教員活動評価委員会 委員 2015/05/01-2016/03/31
大学評価委員会 委員 2016/04/01-
教育制度委員会 委員 2016/04/01-2018/03/31
教育制度委員会WG1 委員 2016/04/01-2017/03/31
原子力研究整備委員会 委員 2014/04/01-2016/03/31
京都大学研究公正委員会 委員 2015/03/01-2016/03/31
京都大学動物実験委員会 委員 2018/02/01-2018/09/30
学生生活委員会 委員 2018/04/01-2020/03/31
学生生活委員会第三小委員会 委員 2018/04/01-2020/03/31
障害者入試委員会 委員 2018/04/01-2019/03/31
大学評価委員会 委員 2016/04/01-2019/03/31
学生表彰選考委員会 委員 -2020/03/31
学生生活委員会第三小委員会 委員長 2018/04/01-2020/03/31
副学長 2020/10/01-2022/09/30
教育制度委員会教育質保証専門委員会 副委員長 2020/10/01-
部局長会議 2020/10/01-2022/09/30
研究科長部会 2020/10/01-2022/09/30

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Faculty management (title, position)
Title Period
教務委員長 2011/04/01-2012/03/31
国際交流委員会 委員 2011/04/01-2020/03/31
将来計画委員会 委員 2009/04/01-2014/03/31
エネルギー管理委員会 委員 2011/04/01-2012/03/31
自己評価等調査検討委員会 委員 2014/04/01-2020/03/31
寄附講座検討委員会 委員 2011/04/01-2014/03/31
寄附講座「医薬産業政策学講座」運営委員 2011/04/01-2014/03/31
統合薬学教育開発センター運営委員会 委員 2010/04/01-2014/03/31
実務実習委員会 委員長 2010/04/01-2014/03/31
安全環境委員長 2012/04/01-2013/03/31
ハラスメント相談窓口 2012/04/01-2014/03/31
将来計画委員会 委員長 2014/04/01-2016/03/31
予算委員会 委員 2013/04/01-2020/03/31
元素分析研究施設・質量分析室運営委員会 委員 2014/04/01-2016/03/31
超伝導NMRスペクトロメーター室運営管理委員会 委員 2014/04/01-2016/03/31
エネルギー管理委員会 委員 2014/04/01-2020/03/31
人権委員会 委員 2013/04/01-2016/03/31
統合薬学教育開発センター運営委員会 委員長 2014/04/01-2016/03/31
寄附講座検討委員会 委員長 2014/04/01-2016/03/31
寄附講座「ナノバイオ医薬創成科学講座」運営委員 2014/04/01-2016/03/31
兼業審査・利益相反審査委員会 委員長 2014/04/01-2016/03/31
薬用植物園管理委員会 委員長 2014/04/01-2016/03/31
国際交流委員会 委員 2014/04/01-2021/03/31
学生便覧編集委員 2011/04/01-2012/03/31
環境・安全衛生委員会 委員長 2012/04/01-2014/03/31
教務委員会 副委員長 2012/04/01-2014/03/31
薬学研究科薬学専攻長 2009/04/01-2012/03/31
薬学研究科 薬学専攻長 2016/04/01-2018/03/31
薬学科 学科長 2016/04/01-2018/03/31
将来計画委員会 委員 2016/04/01-2020/03/31
実務実習委員会 委員長 2016/04/01-2020/03/31
教務委員会 委員 2016/04/01-2018/03/31
薬用植物園管理委員会 委員 2016/04/01-2020/03/31
動物実験委員会委員長 2018/04/01-2021/03/31
自己評価等調査検討委員会 委員長 2010/04/01-2014/03/31
人権委員会 委員 2021/04/01-2022/03/31
ハラスメント相談窓口 2021/04/01-2022/03/31
統合薬学教育開発センター運営委員会 委員 2016/04/01-2022/03/31
寄附講座検討委員会 委員 2016/04/01-2020/03/31
寄附講座「ナノバイオ医薬創成科学講座」運営委員 2017/04/01-2021/03/31
図書委員会 委員 2017/04/01-2018/03/31

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Academic organizations (administrative history with title(s), position(s), etc.)
Organization name(Japanese) Organization name(English) Title(Japanese) Title(English) Period
日本DDS学会 評議員 1997/5-
日本薬物動態学会 評議員 1998/10-
日本薬剤学会 評議員 1998/5-
日本DDS学会 幹事 2003/7-2008/6
日本薬剤学会 理事 2007/5-2011/4
日本DDS学会 常務理事 2008/7-2012/6
日本DDS学会 副理事長 2012/7-2015/7
日本薬剤学会 理事 2014/4-2016/3
日本DDS学会 理事長 2015/7-2018/06/
日本薬学会 副会頭 2017/4-2019/03/
日本薬剤学会 理事 2018/7-
日本核酸医薬学会 主幹事 2015/4-2018/3
日本薬学会 会頭 2019/4-2021/3
日本DDS学会 顧問 2018/6-
日本薬学会 顧問 2021/4-

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Academic organizations (editor, editing team)
Organization name(Japanese) Organization name(English) Journal name(Japanese) Journal name(English) Title Period
日本DDS学会 日本DDS学会機関誌 編集委員長 2010/7-2015/7
Advanced Drug Delivery Reviews Editor 2006-2011
European Journal of Pharmaceutical Sciences Editorial Board 2002-
Drug Metabolism and Pharmacokinetics Editorial Board 2002-
Journal of Biochemistry Editorial Advisory Board 2000-
Pharmaceutical Research Editorial advisory board 2001-
Biological and Pharmaceutical Bulletin Editorial Board 1999-2003