髙田 穣

Last Update: 2021/06/30 20:18:36

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Name(Kanji/Kana/Abecedarium Latinum)
髙田 穣/タカタ ミノル/Takata, Minoru
Primary Affiliation(Org1/Job title)
Graduate School of Biostudies/Professor
Affiliated programs (koza)
Org1 Job title
Graduate School of Medicine Professor
Graduate School of Medicine Professor
Contact Address
Type Address(Japanese) Address(English)
Office
Phone
Type Number
Office
E-mail Address
E-mail address
mtakata @ house.rbc.kyoto-u.ac.jp
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
放射線影響学会
日本分子生物学会
日本生化学会
日本癌学会
日本人類遺伝学会
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 岡山大学
High School
Highschool Kana
広島大学附属福山高等学校
Personal Website(s) (URL(s))
URL
http://www.rbc.kyoto-u.ac.jp/late-effect
ORCID ID
https://orcid.org/0000-0002-4926-3675
researchmap URL
https://researchmap.jp/read0062989
Research Topics
(Japanese)
中心的な研究テーマとしては、「ゲノム損傷ストレスへの生体防御応答シグナル伝達の解明」と設定している。 ゲノム損傷ストレスは、放射線を含めた「外的要因」や細胞内代謝やゲノム配列そのものなどの「内的要因」によるものの両面を考慮して進めている。
(English)
My lab focuses on the mechanisms of self-protective DNA damage signaling elicited by exogenous (e.g. radiation) and endogenous (caused by cell metabolism) genome damage.
Overview of the research
(Japanese)
応用的側面からの研究課題として、がん、遺伝病、放射線晩発障害の解明をめざし、以下のものを展開中。 1.ファンコニ貧血、家族性乳がんなどのゲノム不安定性症候群の病態 2.染色体脆弱部位をはじめとする非コードDNA領域の安定化機構 3.ファンコニ貧血とその類似病態の新原因規遺伝子の同定 4.がん遺伝子による複製ストレス応答 5.低頻度ゲノム二重鎖切断に対する細胞応答
(English)
I am interested in human disorders such as chromosome instability disorders, cancer, and late effects of radiation. The current topic is as follows: 1. Pathogenesis of Fanconi anemia and familial breast cancer 2. Stabilization mechanisms of the non-coding DNA regions including the common fragile sites 3. Identification of novel genes involved in Fanconi anemia and related disorders 4. Replication stress caused by oncogene activation 5. Cellular response toward single or a few double strand breaks in the genome
Fields of research (key words)
Key words(Japanese) Key words(English)
DNA損傷シグナリング DNA damage signaling
DNA修復 DNA repair
チェックポイント checkpoint
ファンコニ貧血 Fanconi anemia
非コードDNA non-coding DNA
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Xinlin Xu, Yixi Xu, Ruiyuan Guo, Ran Xu, Congcong Fu, Mengtan Xing, Hiroyuki Sasanuma, Qing Li, Minoru Takata, Shunichi Takeda, Rong Guo, Dongyi Xu Xinlin Xu, Yixi Xu, Ruiyuan Guo, Ran Xu, Congcong Fu, Mengtan Xing, Hiroyuki Sasanuma, Qing Li, Minoru Takata, Shunichi Takeda, Rong Guo, Dongyi Xu Xinlin Xu, Yixi Xu, Ruiyuan Guo, Ran Xu, Congcong Fu, Mengtan Xing, Hiroyuki Sasanuma, Qing Li, Minoru Takata, Shunichi Takeda, Rong Guo, Dongyi Xu Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress. Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress. Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress. Nature structural & molecular biology, 28, 6, 487-500 Nature structural & molecular biology, 28, 6, 487-500 Nature structural & molecular biology, 28, 6, 487-500 2021/06 English Research paper(scientific journal) Disclose to all
Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K Saito, Minoru Takata Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K Saito, Minoru Takata Anfeng Mu, Asuka Hira, Akira Niwa, Mitsujiro Osawa, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Kazuko Inoue, Keita Kondo, Masato T Kanemaki, Tomonari Matsuda, Etsuro Ito, Seiji Kojima, Tatsutoshi Nakahata, Seishi Ogawa, Keigo Tanaka, Keitaro Matsuo, Megumu K Saito, Minoru Takata Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. Blood, 137, 15, 2021-2032 Blood, 137, 15, 2021-2032 Blood, 137, 15, 2021-2032 2021/04/15 English Research paper(scientific journal) Disclose to all
Yusuke Okamoto, Masako Abe, Anfeng Mu, Yasuko Tempaku, Colette B Rogers, Ayako L Mochizuki, Yoko Katsuki, Masato T Kanemaki, Akifumi Takaori-Kondo, Alexandra Sobeck, Anja-Katrin Bielinsky, Minoru Takata Yusuke Okamoto, Masako Abe, Anfeng Mu, Yasuko Tempaku, Colette B Rogers, Ayako L Mochizuki, Yoko Katsuki, Masato T Kanemaki, Akifumi Takaori-Kondo, Alexandra Sobeck, Anja-Katrin Bielinsky, Minoru Takata Yusuke Okamoto, Masako Abe, Anfeng Mu, Yasuko Tempaku, Colette B Rogers, Ayako L Mochizuki, Yoko Katsuki, Masato T Kanemaki, Akifumi Takaori-Kondo, Alexandra Sobeck, Anja-Katrin Bielinsky, Minoru Takata SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells. SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells. SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells. Blood, 137, 3, 336-348 Blood, 137, 3, 336-348 Blood, 137, 3, 336-348 2021/01/21 Refereed English Research paper(scientific journal) Disclose to all
Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R G Hodskinson, Minoru Takata, Ketan J Patel Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R G Hodskinson, Minoru Takata, Ketan J Patel Felix A Dingler, Meng Wang, Anfeng Mu, Christopher L Millington, Nina Oberbeck, Sam Watcham, Lucas B Pontel, Ashley N Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L Cordell, Paul S Monks, Rui Yu, Nicola K Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R G Hodskinson, Minoru Takata, Ketan J Patel Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Molecular cell, 80, 6, 996-1012 Molecular cell, 80, 6, 996-1012 Molecular cell, 80, 6, 996-1012 2020/12/17 English Research paper(scientific journal) Disclose to all
Toshiaki Nakano, Mahmoud Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Minoru Takata, Shin-ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano Toshiaki Nakano, Mahmoud Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Minoru Takata, Shin-ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano Toshiaki Nakano, Mahmoud Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Minoru Takata, Shin-ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells PLOS One, accepted PLOS One, accepted PLOS One, accepted 2020/06 Refereed Disclose to all
Francesco Rossi, Anne Helbling-Leclerc, Ryotaro Kawasumi, Nanda Kumar Jegadesan, Xinlin Xu, Pierre Devulder, Takuya Abe, Minoru Takata, Dongyi Xu, Filippo Rosselli, Dana Branzei Francesco Rossi, Anne Helbling-Leclerc, Ryotaro Kawasumi, Nanda Kumar Jegadesan, Xinlin Xu, Pierre Devulder, Takuya Abe, Minoru Takata, Dongyi Xu, Filippo Rosselli, Dana Branzei Francesco Rossi, Anne Helbling-Leclerc, Ryotaro Kawasumi, Nanda Kumar Jegadesan, Xinlin Xu, Pierre Devulder, Takuya Abe, Minoru Takata, Dongyi Xu, Filippo Rosselli, Dana Branzei SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. EMBO reports, 21, 2, e48222 EMBO reports, 21, 2, e48222 EMBO reports, 21, 2, e48222 2020/02/05 English Research paper(scientific journal) Disclose to all
Hotta K, Yanai H, Ohashi K, Ninomiya K, Nakashima H, Kayatani H, Takata M, Kiura K Hotta K, Yanai H, Ohashi K, Ninomiya K, Nakashima H, Kayatani H, Takata M, Kiura K Hotta K, Yanai H, Ohashi K, Ninomiya K, Nakashima H, Kayatani H, Takata M, Kiura K Pilot evaluation of a HER2 testing in non-small-cell lung cancer. Pilot evaluation of a HER2 testing in non-small-cell lung cancer. Pilot evaluation of a HER2 testing in non-small-cell lung cancer. Journal of clinical pathology Journal of clinical pathology Journal of clinical pathology 2019/12 Refereed Disclose to all
Minako Mori, Asuka Hira, Kenichi Yoshida, Hideki Muramatsu, Yusuke Okuno, Yuichi Shiraishi, Michiko Anmae, Jun Yasuda, Shu Tadaka, Kengo Kinoshita, Tomoo Osumi, Yasushi Noguchi, Souichi Adachi, Ryoji Kobayashi, Hiroshi Kawabata, Kohsuke Imai, Tomohiro Morio, Kazuo Tamura, Akifumi Takaori-Kondo, Masayuki Yamamoto, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa, Keitaro Matsuo, Hiromasa Yabe, Miharu Yabe, Minoru Takata Minako Mori, Asuka Hira, Kenichi Yoshida, Hideki Muramatsu, Yusuke Okuno, Yuichi Shiraishi, Michiko Anmae, Jun Yasuda, Shu Tadaka, Kengo Kinoshita, Tomoo Osumi, Yasushi Noguchi, Souichi Adachi, Ryoji Kobayashi, Hiroshi Kawabata, Kohsuke Imai, Tomohiro Morio, Kazuo Tamura, Akifumi Takaori-Kondo, Masayuki Yamamoto, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa, Keitaro Matsuo, Hiromasa Yabe, Miharu Yabe, Minoru Takata Minako Mori, Asuka Hira, Kenichi Yoshida, Hideki Muramatsu, Yusuke Okuno, Yuichi Shiraishi, Michiko Anmae, Jun Yasuda, Shu Tadaka, Kengo Kinoshita, Tomoo Osumi, Yasushi Noguchi, Souichi Adachi, Ryoji Kobayashi, Hiroshi Kawabata, Kohsuke Imai, Tomohiro Morio, Kazuo Tamura, Akifumi Takaori-Kondo, Masayuki Yamamoto, Satoru Miyano, Seiji Kojima, Etsuro Ito, Seishi Ogawa, Keitaro Matsuo, Hiromasa Yabe, Miharu Yabe, Minoru Takata Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica, 104, 10, 1962-1973 Haematologica, 104, 10, 1962-1973 Haematologica, 104, 10, 1962-1973 2019/10 Refereed English Research paper(scientific journal) Disclose to all
Mori Minako, Hira Asuka, Yoshida Kenichi, Muramatsu Hideki, Okuno Yusuke, Anmae Michiko, Tamura Kazuo, Yasuda Jun, Osumi Tomoo, Noguchi Yasushi, Adachi Souichi, Kawabata Hiroshi, Takaori-Kondo Akifumi, Kojima Seiji, Ogawa Seishi, Yabe Hiromasa, Yabe Miharu, Takata Minoru Mori Minako, Hira Asuka, Yoshida Kenichi, Muramatsu Hideki, Okuno Yusuke, Anmae Michiko, Tamura Kazuo, Yasuda Jun, Osumi Tomoo, Noguchi Yasushi, Adachi Souichi, Kawabata Hiroshi, Takaori-Kondo Akifumi, Kojima Seiji, Ogawa Seishi, Yabe Hiromasa, Yabe Miharu, Takata Minoru Mori Minako, Hira Asuka, Yoshida Kenichi, Muramatsu Hideki, Okuno Yusuke, Anmae Michiko, Tamura Kazuo, Yasuda Jun, Osumi Tomoo, Noguchi Yasushi, Adachi Souichi, Kawabata Hiroshi, Takaori-Kondo Akifumi, Kojima Seiji, Ogawa Seishi, Yabe Hiromasa, Yabe Miharu, Takata Minoru Characterization of Pathogenic Variants and Clinical Phenotypes in 117 Japanese Fanconi Anemia Patients Characterization of Pathogenic Variants and Clinical Phenotypes in 117 Japanese Fanconi Anemia Patients Characterization of Pathogenic Variants and Clinical Phenotypes in 117 Japanese Fanconi Anemia Patients BLOOD, 132 BLOOD, 132 BLOOD, 132 2018/11/29 English Research paper(international conference proceedings) Disclose to all
Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Hitoshi Kanno, Yamaguchi Hiroki, Ohga Shouichi, Manabe Atsushi, Harigae Hideo, Kunishima Shinji, Ishii Eiichi, Kobayashi Masao, Koike Kenichi, Watanabe Kenichiro, Ito Etsuro, Takata Minoru, Yabe Miharu, Ogawa Seishi, Miyano Satoru, Kojima Seiji, Takahashi Yoshiyuki Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Hitoshi Kanno, Yamaguchi Hiroki, Ohga Shouichi, Manabe Atsushi, Harigae Hideo, Kunishima Shinji, Ishii Eiichi, Kobayashi Masao, Koike Kenichi, Watanabe Kenichiro, Ito Etsuro, Takata Minoru, Yabe Miharu, Ogawa Seishi, Miyano Satoru, Kojima Seiji, Takahashi Yoshiyuki Narita Atsushi, Muramatsu Hideki, Okuno Yusuke, Yoshida Kenichi, Shiraishi Yuichi, Sakaguchi Hirotoshi, Kawashima Nozomu, Wang Xinan, Xu Yinyan, Chiba Kenichi, Tanaka Hiroko, Hama Asahito, Sanada Masashi, Hitoshi Kanno, Yamaguchi Hiroki, Ohga Shouichi, Manabe Atsushi, Harigae Hideo, Kunishima Shinji, Ishii Eiichi, Kobayashi Masao, Koike Kenichi, Watanabe Kenichiro, Ito Etsuro, Takata Minoru, Yabe Miharu, Ogawa Seishi, Miyano Satoru, Kojima Seiji, Takahashi Yoshiyuki Diagnosis of Inherited Bone Marrow Failure Syndromes Using Sequencing Approaches Diagnosis of Inherited Bone Marrow Failure Syndromes Using Sequencing Approaches Diagnosis of Inherited Bone Marrow Failure Syndromes Using Sequencing Approaches PEDIATRIC BLOOD & CANCER, 65, S7-S7 PEDIATRIC BLOOD & CANCER, 65, S7-S7 PEDIATRIC BLOOD & CANCER, 65, S7-S7 2018/11 English Research paper(scientific journal) Disclose to all
Yabe M, Koike T, Ohtsubo K, Imai E, Morimoto T, Takakura H, Koh K, Yoshida K, Ogawa S, Ito E, Okuno Y, Muramatsu H, Kojima S, Matsuo K, Mori M, Hira A, Takata M, Yabe H Yabe M, Koike T, Ohtsubo K, Imai E, Morimoto T, Takakura H, Koh K, Yoshida K, Ogawa S, Ito E, Okuno Y, Muramatsu H, Kojima S, Matsuo K, Mori M, Hira A, Takata M, Yabe H Yabe M, Koike T, Ohtsubo K, Imai E, Morimoto T, Takakura H, Koh K, Yoshida K, Ogawa S, Ito E, Okuno Y, Muramatsu H, Kojima S, Matsuo K, Mori M, Hira A, Takata M, Yabe H Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Ann Hematol. Ann Hematol. Epub ahead of print Ann Hematol. 2018/10 Refereed English Disclose to all
T Abe T, Ooka M, Kawasumi R, Miyata K, Takata M, Hirota K, Branzei D Abe T, Ooka M, Kawasumi R, Miyata K, Takata M, Hirota K, Branzei D T Abe T, Ooka M, Kawasumi R, Miyata K, Takata M, Hirota K, Branzei D Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites. Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites. Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites. Proc Natl Acad Sci U S A, 115, 33, 8412-8417 Proc Natl Acad Sci U S A, 115, 33, 8412-8417 Proc Natl Acad Sci U S A, 115, 33, 8412-8417 2018/08 Refereed English Disclose to all
Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Mol Cell, 71, 1, 25-41 Mol Cell, 71, 1, 25-41 Mol Cell, 71, 1, 25-41 2018/06 Refereed English Research paper(scientific journal) Disclose to all
Yusuke Okamoto, Watal M. Iwasaki, Kazuto Kugou, Kazuki K. Takahashi, Arisa Oda, Koichi Sato, Wataru Kobayashi, Hidehiko Kawai, Ryo Sakasai, Akifumi Takaori-Kondo, Takashi Yamamoto, Masato T. Kanemaki, Masato Taoka, Toshiaki Isobe, Hitoshi Kurumizaka, Hideki Innan, Kunihiro Ohta, Masamichi Ishiai, Minoru Takata Yusuke Okamoto, Watal M. Iwasaki, Kazuto Kugou, Kazuki K. Takahashi, Arisa Oda, Koichi Sato, Wataru Kobayashi, Hidehiko Kawai, Ryo Sakasai, Akifumi Takaori-Kondo, Takashi Yamamoto, Masato T. Kanemaki, Masato Taoka, Toshiaki Isobe, Hitoshi Kurumizaka, Hideki Innan, Kunihiro Ohta, Masamichi Ishiai, Minoru Takata Yusuke Okamoto, Watal M. Iwasaki, Kazuto Kugou, Kazuki K. Takahashi, Arisa Oda, Koichi Sato, Wataru Kobayashi, Hidehiko Kawai, Ryo Sakasai, Akifumi Takaori-Kondo, Takashi Yamamoto, Masato T. Kanemaki, Masato Taoka, Toshiaki Isobe, Hitoshi Kurumizaka, Hideki Innan, Kunihiro Ohta, Masamichi Ishiai, Minoru Takata Replication stress induces accumulation of FANCD2 at central region of large fragile genes Replication stress induces accumulation of FANCD2 at central region of large fragile genes Replication stress induces accumulation of FANCD2 at central region of large fragile genes NUCLEIC ACIDS RESEARCH, 46, 6, 2932-2944 NUCLEIC ACIDS RESEARCH, 46, 6, 2932-2944 NUCLEIC ACIDS RESEARCH, 46, 6, 2932-2944 2018/04 Refereed English Research paper(scientific journal) Disclose to all
稲野将二郎, 高田穣 稲野将二郎, 高田穣 ファンコニ貧血の新規原因遺伝子RFWD3/FANCWの機能解析から明らかになった相同組換え反応制御機構. ファンコニ貧血の新規原因遺伝子RFWD3/FANCWの機能解析から明らかになった相同組換え反応制御機構. 生化学, 90, 3, 371-380 生化学, 90, 3, 371-380 , 90, 3, 371-380 2018 Japanese Disclose to all
髙田 穰 髙田 穰 ファンコニ貧血の新規原因遺伝子RFWD3の同定とその機能解析 ファンコニ貧血の新規原因遺伝子RFWD3の同定とその機能解析 医学のあゆみ TOPICS, 266, 545-546 医学のあゆみ TOPICS, 266, 545-546 , 266, 545-546 2018 Japanese Disclose to all
Ayako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai, Minoru Takata, Gen Kondoh, Hitomi Watanabe, Norio Nakatsuji, Shinichiro Chuma Ayako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai, Minoru Takata, Gen Kondoh, Hitomi Watanabe, Norio Nakatsuji, Shinichiro Chuma Ayako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai, Minoru Takata, Gen Kondoh, Hitomi Watanabe, Norio Nakatsuji, Shinichiro Chuma PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice MOLECULAR AND CELLULAR BIOLOGY, 37, 23 MOLECULAR AND CELLULAR BIOLOGY, 37, 23 MOLECULAR AND CELLULAR BIOLOGY, 37, 23 2017/12 Refereed English Research paper(scientific journal) Disclose to all
Masamichi Ishiai, Koichi Sato, Junya Tomida, Hiroyuki Kitao, Hitoshi Kurumizaka, Minoru Takata Masamichi Ishiai, Koichi Sato, Junya Tomida, Hiroyuki Kitao, Hitoshi Kurumizaka, Minoru Takata Masamichi Ishiai, Koichi Sato, Junya Tomida, Hiroyuki Kitao, Hitoshi Kurumizaka, Minoru Takata Activation of the FA pathway mediated by phosphorylation and ubiquitination Activation of the FA pathway mediated by phosphorylation and ubiquitination Activation of the FA pathway mediated by phosphorylation and ubiquitination MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 89-95 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 89-95 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 803, 89-95 2017/10 Refereed English Disclose to all
Minoru Takata Minoru Takata Minoru Takata Mutation Research special section "Protein modifications in DNA repair and cancer" Editorial. Mutation Research special section "Protein modifications in DNA repair and cancer" Editorial. Mutation Research special section "Protein modifications in DNA repair and cancer" Editorial. Mutat Res., 803-805 Mutat Res., 803-805 Mutat Res., 803-805 2017/10 Refereed English Disclose to all
Kei Kadoda, Takahito Moriwaki, Masataka Tsuda, Hiroyuki Sasanuma, Masamichi Ishiai, Minoru Takata, Hiroshi Ide, Shin-ichiro Masunaga, Shunichi Takeda, Keizo Tano Kei Kadoda, Takahito Moriwaki, Masataka Tsuda, Hiroyuki Sasanuma, Masamichi Ishiai, Minoru Takata, Hiroshi Ide, Shin-ichiro Masunaga, Shunichi Takeda, Keizo Tano Kei Kadoda, Takahito Moriwaki, Masataka Tsuda, Hiroyuki Sasanuma, Masamichi Ishiai, Minoru Takata, Hiroshi Ide, Shin-ichiro Masunaga, Shunichi Takeda, Keizo Tano Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells PLOS ONE, 12, 9 PLOS ONE, 12, 9 PLOS ONE, 12, 9 2017/09 Refereed English Research paper(scientific journal) Disclose to all
Kerstin Knies, Shojiro Inano, Maria J. Ramirez, Masamichi Ishiai, Jordi Surralles, Minoru Takata, Detlev Schindler Kerstin Knies, Shojiro Inano, Maria J. Ramirez, Masamichi Ishiai, Jordi Surralles, Minoru Takata, Detlev Schindler Kerstin Knies, Shojiro Inano, Maria J. Ramirez, Masamichi Ishiai, Jordi Surralles, Minoru Takata, Detlev Schindler Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia JOURNAL OF CLINICAL INVESTIGATION, 127, 8, 3013-3027 JOURNAL OF CLINICAL INVESTIGATION, 127, 8, 3013-3027 JOURNAL OF CLINICAL INVESTIGATION, 127, 8, 3013-3027 2017/08 Refereed English Research paper(scientific journal) Disclose to all
Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Common Variable Immunodeficiency Caused by FANC Mutations Common Variable Immunodeficiency Caused by FANC Mutations Common Variable Immunodeficiency Caused by FANC Mutations Journal of Clinical Immunology, 37, 5, 434-444 Journal of Clinical Immunology, 37, 5, 434-444 Journal of Clinical Immunology, 37, 5, 434-444 2017/07/01 Refereed English Research paper(scientific journal) Disclose to all
Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama Common Variable Immunodeficiency Caused by FANC Mutations Common Variable Immunodeficiency Caused by FANC Mutations Common Variable Immunodeficiency Caused by FANC Mutations JOURNAL OF CLINICAL IMMUNOLOGY, 37, 5, 434-444 JOURNAL OF CLINICAL IMMUNOLOGY, 37, 5, 434-444 JOURNAL OF CLINICAL IMMUNOLOGY, 37, 5, 434-444 2017/07 Refereed English Research paper(scientific journal) Disclose to all
稲野将二郎, 佐藤浩一, 胡桃坂仁志, 高田 穣 稲野将二郎, 佐藤浩一, 胡桃坂仁志, 高田 穣 Fanconi貧血の新規の原因タンパク質RFWD3による相同組換えの制御. Fanconi貧血の新規の原因タンパク質RFWD3による相同組換えの制御. ライフサイエンス 新着論文レビュー ライフサイエンス 新着論文レビュー 2017/07 Japanese Disclose to all
Shojiro Inano, Koichi Sato, Yoko Katsuki, Wataru Kobayashi, Hiroki Tanaka, Kazuhiro Nakajima, Shinichiro Nakada, Hiroyuki Miyoshi, Kerstin Knies, Akifumi Takaori-Kondo, Detlev Schindler, Masamichi Ishiai, Hitoshi Kurumizaka, Minoru Takata Shojiro Inano, Koichi Sato, Yoko Katsuki, Wataru Kobayashi, Hiroki Tanaka, Kazuhiro Nakajima, Shinichiro Nakada, Hiroyuki Miyoshi, Kerstin Knies, Akifumi Takaori-Kondo, Detlev Schindler, Masamichi Ishiai, Hitoshi Kurumizaka, Minoru Takata Shojiro Inano, Koichi Sato, Yoko Katsuki, Wataru Kobayashi, Hiroki Tanaka, Kazuhiro Nakajima, Shinichiro Nakada, Hiroyuki Miyoshi, Kerstin Knies, Akifumi Takaori-Kondo, Detlev Schindler, Masamichi Ishiai, Hitoshi Kurumizaka, Minoru Takata RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination MOLECULAR CELL, 66, 5, 622-+ MOLECULAR CELL, 66, 5, 622-+ MOLECULAR CELL, 66, 5, 622-+ 2017/06 Refereed English Research paper(scientific journal) Disclose to all
Hideki Muramatsu, Yusuke Okuno, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Atsushi Narita, Hirotoshi Sakaguchi, Nozomu Kawashima, Xinan Wang, Yinyan Xu, Kenichi Chiba, Hiroko Tanaka, Asahito Hama, Masashi Sanada, Yoshiyuki Takahashi, Hitoshi Kanno, Hiroki Yamaguchi, Shouichi Ohga, Atsushi Manabe, Hideo Harigae, Shinji Kunishima, Eiichi Ishii, Masao Kobayashi, Kenichi Koike, Kenichiro Watanabe, Etsuro Ito, Minoru Takata, Miharu Yabe, Seishi Ogawa, Satoru Miyano, Seiji Kojima Hideki Muramatsu, Yusuke Okuno, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Atsushi Narita, Hirotoshi Sakaguchi, Nozomu Kawashima, Xinan Wang, Yinyan Xu, Kenichi Chiba, Hiroko Tanaka, Asahito Hama, Masashi Sanada, Yoshiyuki Takahashi, Hitoshi Kanno, Hiroki Yamaguchi, Shouichi Ohga, Atsushi Manabe, Hideo Harigae, Shinji Kunishima, Eiichi Ishii, Masao Kobayashi, Kenichi Koike, Kenichiro Watanabe, Etsuro Ito, Minoru Takata, Miharu Yabe, Seishi Ogawa, Satoru Miyano, Seiji Kojima Hideki Muramatsu, Yusuke Okuno, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Atsushi Narita, Hirotoshi Sakaguchi, Nozomu Kawashima, Xinan Wang, Yinyan Xu, Kenichi Chiba, Hiroko Tanaka, Asahito Hama, Masashi Sanada, Yoshiyuki Takahashi, Hitoshi Kanno, Hiroki Yamaguchi, Shouichi Ohga, Atsushi Manabe, Hideo Harigae, Shinji Kunishima, Eiichi Ishii, Masao Kobayashi, Kenichi Koike, Kenichiro Watanabe, Etsuro Ito, Minoru Takata, Miharu Yabe, Seishi Ogawa, Satoru Miyano, Seiji Kojima Clinical Utility of Next-generation Sequencing for Inherited Bone Marrow Failure Syndromes. Clinical Utility of Next-generation Sequencing for Inherited Bone Marrow Failure Syndromes. Clinical Utility of Next-generation Sequencing for Inherited Bone Marrow Failure Syndromes. Genet Med. Genet Med. Genet Med. 2017/01 Refereed English Disclose to all
TAKATA Minoru 髙田 穰 TAKATA Minoru "Protein modifications in DNA repair and cancer" Editorial. "Protein modifications in DNA repair and cancer" Editorial. "Protein modifications in DNA repair and cancer" Editorial. Mutation Research special section, 803-805, 42-42 Mutation Research special section, 803-805, 42-42 Mutation Research special section, 803-805, 42-42 2017 Refereed English Disclose to all
稲野将二郎, 高田穣 稲野将二郎, 高田穣 新規Fanconi anemia 遺伝子RFWD3/FANCWの発見と機能解明。 新規Fanconi anemia 遺伝子RFWD3/FANCWの発見と機能解明。 小児血液がん学会誌, 54, 5, 287-293 小児血液がん学会誌, 54, 5, 287-293 , 54, 5, 287-293 2017 Japanese Disclose to all
Koichi Sato, Mayo Shimomuki, Yoko Katsuki, Daisuke Takahashi, Wataru Kobayashi, Masamichi Ishiai, Hiroyuki Miyoshi, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Mayo Shimomuki, Yoko Katsuki, Daisuke Takahashi, Wataru Kobayashi, Masamichi Ishiai, Hiroyuki Miyoshi, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Mayo Shimomuki, Yoko Katsuki, Daisuke Takahashi, Wataru Kobayashi, Masamichi Ishiai, Hiroyuki Miyoshi, Minoru Takata, Hitoshi Kurumizaka FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5 '-DNA end FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5 '-DNA end FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5 '-DNA end NUCLEIC ACIDS RESEARCH, 44, 22, 10758-10771 NUCLEIC ACIDS RESEARCH, 44, 22, 10758-10771 NUCLEIC ACIDS RESEARCH, 44, 22, 10758-10771 2016/12 Refereed English Research paper(scientific journal) Disclose to all
Chen Ling, Jing Huang, Zhijiang Yan, Yongjiang Li, Mioko Ohzeki, Masamichi Ishiai, Dongyi Xu, Minoru Takata, Michael Seidman, Weidong Wang Chen Ling, Jing Huang, Zhijiang Yan, Yongjiang Li, Mioko Ohzeki, Masamichi Ishiai, Dongyi Xu, Minoru Takata, Michael Seidman, Weidong Wang Chen Ling, Jing Huang, Zhijiang Yan, Yongjiang Li, Mioko Ohzeki, Masamichi Ishiai, Dongyi Xu, Minoru Takata, Michael Seidman, Weidong Wang Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks CELL DISCOVERY, 2 CELL DISCOVERY, 2 CELL DISCOVERY, 2 2016/12 Refereed English Research paper(scientific journal) Disclose to all
Miharu Yabe, Hiromasa Yabe, Tsuyoshi Morimoto, Akiko Fukumura, Keisuke Ohtsubo, Takashi Koike, Kenichi Yoshida, Seishi Ogawa, Etsuro Ito, Yusuke Okuno, Hideki Muramatsu, Seiji Kojima, Keitaro Matsuo, Asuka Hira, Minoru Takata Miharu Yabe, Hiromasa Yabe, Tsuyoshi Morimoto, Akiko Fukumura, Keisuke Ohtsubo, Takashi Koike, Kenichi Yoshida, Seishi Ogawa, Etsuro Ito, Yusuke Okuno, Hideki Muramatsu, Seiji Kojima, Keitaro Matsuo, Asuka Hira, Minoru Takata Miharu Yabe, Hiromasa Yabe, Tsuyoshi Morimoto, Akiko Fukumura, Keisuke Ohtsubo, Takashi Koike, Kenichi Yoshida, Seishi Ogawa, Etsuro Ito, Yusuke Okuno, Hideki Muramatsu, Seiji Kojima, Keitaro Matsuo, Asuka Hira, Minoru Takata The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype BRITISH JOURNAL OF HAEMATOLOGY, 175, 3, 457-461 BRITISH JOURNAL OF HAEMATOLOGY, 175, 3, 457-461 BRITISH JOURNAL OF HAEMATOLOGY, 175, 3, 457-461 2016/11 Refereed English Research paper(scientific journal) Disclose to all
Yoko Katsuki, Minoru Takata Yoko Katsuki, Minoru Takata Yoko Katsuki, Minoru Takata Defects in homologous recombination repair behind the human diseases: FA and HBOC Defects in homologous recombination repair behind the human diseases: FA and HBOC Defects in homologous recombination repair behind the human diseases: FA and HBOC ENDOCRINE-RELATED CANCER, 23, 10, T19-T37 ENDOCRINE-RELATED CANCER, 23, 10, T19-T37 ENDOCRINE-RELATED CANCER, 23, 10, T19-T37 2016/10 Refereed English Disclose to all
Kiyohiro Hashimoto, Vyom Sharma, Hiroyuki Sasanuma, Xu Tian, Minoru Takata, Shunichi Takeda, James A Swenberg, Jun Nakamura Kiyohiro Hashimoto, Vyom Sharma, Hiroyuki Sasanuma, Xu Tian, Minoru Takata, Shunichi Takeda, James A Swenberg, Jun Nakamura Kiyohiro Hashimoto, Vyom Sharma, Hiroyuki Sasanuma, Xu Tian, Minoru Takata, Shunichi Takeda, James A Swenberg, Jun Nakamura Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget, 7, 37, 59795-59808 Oncotarget, 7, 37, 59795-59808 Oncotarget, 7, 37, 59795-59808 2016/09/13 Refereed English Disclose to all
Masahiro Osawa, Kadoaki Ohashi, Toshio Kubo, Eiki Ichihara, Saburo Takata, Nagio Takigawa, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Masahiro Osawa, Kadoaki Ohashi, Toshio Kubo, Eiki Ichihara, Saburo Takata, Nagio Takigawa, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Masahiro Osawa, Kadoaki Ohashi, Toshio Kubo, Eiki Ichihara, Saburo Takata, Nagio Takigawa, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation ACTA MEDICA OKAYAMA, 70, 4, 243-253 ACTA MEDICA OKAYAMA, 70, 4, 243-253 ACTA MEDICA OKAYAMA, 70, 4, 243-253 2016/08 Refereed English Research paper(scientific journal) Disclose to all
Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata The fanconi anemia pathway and interstrand cross-link repair The fanconi anemia pathway and interstrand cross-link repair The fanconi anemia pathway and interstrand cross-link repair DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology, 175-210 DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology, 175-210 DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology, 175-210 2016/01/01 Refereed English Disclose to all
Xu Tian, Keyur Patel, John R Ridpath, Youjun Chen, Yi-Hui Zhou, Dayna Neo, Jean Clement, Minoru Takata, Shunichi Takeda, Julian Sale, Fred A Wright, James A Swenberg, Jun Nakamura Xu Tian, Keyur Patel, John R Ridpath, Youjun Chen, Yi-Hui Zhou, Dayna Neo, Jean Clement, Minoru Takata, Shunichi Takeda, Julian Sale, Fred A Wright, James A Swenberg, Jun Nakamura Xu Tian, Keyur Patel, John R Ridpath, Youjun Chen, Yi-Hui Zhou, Dayna Neo, Jean Clement, Minoru Takata, Shunichi Takeda, Julian Sale, Fred A Wright, James A Swenberg, Jun Nakamura Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium. PloS one, 11, 12, e0167503 PloS one, 11, 12, e0167503 PloS one, 11, 12, e0167503 2016 Refereed English Disclose to all
Kei-ichi Takata, Junya Tomida, Shelley Reh, Lisa M. Swanhart, Minoru Takata, Neil A. Hukriede, Richard D. Wood Takata KI, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD Kei-ichi Takata, Junya Tomida, Shelley Reh, Lisa M. Swanhart, Minoru Takata, Neil A. Hukriede, Richard D. Wood Conserved Overlapping Gene Arrangement, Restricted Expression, and Biochemical Activities of DNA Polymerase nu (POLN) Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN). Conserved Overlapping Gene Arrangement, Restricted Expression, and Biochemical Activities of DNA Polymerase nu (POLN) JOURNAL OF BIOLOGICAL CHEMISTRY, 290, 40, 24278-24293 J Biol Chem., 290, 40, 24278-24293 JOURNAL OF BIOLOGICAL CHEMISTRY, 290, 40, 24278-24293 2015/10 Refereed English Research paper(scientific journal) Disclose to all
Daisuke Takahashi, Koichi Sato, Emiko Hirayama, Minoru Takata, Hitoshi Kurumizaka Daisuke Takahashi, Koichi Sato, Emiko Hirayama, Minoru Takata, Hitoshi Kurumizaka Daisuke Takahashi, Koichi Sato, Emiko Hirayama, Minoru Takata, Hitoshi Kurumizaka Human FAN1 promotes strand incision in 5 '-flapped DNA complexed with RPA Human FAN1 promotes strand incision in 5 '-flapped DNA complexed with RPA Human FAN1 promotes strand incision in 5 '-flapped DNA complexed with RPA JOURNAL OF BIOCHEMISTRY, 158, 3, 263-270 JOURNAL OF BIOCHEMISTRY, 158, 3, 263-270 JOURNAL OF BIOCHEMISTRY, 158, 3, 263-270 2015/09 Refereed English Research paper(scientific journal) Disclose to all
Asuka Hira, Kenichi Yoshida, Koichi Sato, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Shimamoto, Hidetoshi Tahara, Etsuro Ito, Seiji Kojima, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe Asuka Hira, Kenichi Yoshida, Koichi Sato, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Shimamoto, Hidetoshi Tahara, Etsuro Ito, Seiji Kojima, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe Asuka Hira, Kenichi Yoshida, Koichi Sato, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Akira Shimamoto, Hidetoshi Tahara, Etsuro Ito, Seiji Kojima, Hitoshi Kurumizaka, Seishi Ogawa, Minoru Takata, Hiromasa Yabe, Miharu Yabe Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia AMERICAN JOURNAL OF HUMAN GENETICS, 96, 6, 1001-1007 AMERICAN JOURNAL OF HUMAN GENETICS, 96, 6, 1001-1007 AMERICAN JOURNAL OF HUMAN GENETICS, 96, 6, 1001-1007 2015/06 Refereed English Research paper(scientific journal) Disclose to all
Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, Miharu Yabe Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, Miharu Yabe Minoru Takata, Asuka Hira, Kenichi Yoshida, Koichi Sato, Akira Shimamoto, Hidetoshi Tahara, Hitoshi Kurumizaka, Seishi Ogawa, Hiromasa Yabe, Miharu Yabe Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene DNA REPAIR, 28, 140-141 DNA REPAIR, 28, 140-141 DNA REPAIR, 28, 140-141 2015/04 English Disclose to all
Naoya M. Suzuki, Akira Niwa, Miharu Yabe, Asuka Hira, Chihiro Okada, Naoki Amano, Akira Watanabe, Ken-Ichiro Watanabe, Toshio Heike, Minoru Takata, Tatsutoshi Nakahata, Megumu K. Saita Naoya M. Suzuki, Akira Niwa, Miharu Yabe, Asuka Hira, Chihiro Okada, Naoki Amano, Akira Watanabe, Ken-Ichiro Watanabe, Toshio Heike, Minoru Takata, Tatsutoshi Nakahata, Megumu K. Saita Naoya M. Suzuki, Akira Niwa, Miharu Yabe, Asuka Hira, Chihiro Okada, Naoki Amano, Akira Watanabe, Ken-Ichiro Watanabe, Toshio Heike, Minoru Takata, Tatsutoshi Nakahata, Megumu K. Saita Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors STEM CELLS TRANSLATIONAL MEDICINE, 4, 4, 333-338 STEM CELLS TRANSLATIONAL MEDICINE, 4, 4, 333-338 STEM CELLS TRANSLATIONAL MEDICINE, 4, 4, 333-338 2015/04 Refereed English Research paper(scientific journal) Disclose to all
石合正道, 高田 穣 石合正道, 高田 穣 石合正道, 高田 穣 細胞シグナル操作法 「DNA修復」 細胞シグナル操作法 「DNA修復」 細胞シグナル操作法 「DNA修復」 生体の科学 増大特集, 66, 5, 466-467 生体の科学 増大特集, 66, 5, 466-467 生体の科学 増大特集, 66, 5, 466-467 2015 Japanese Disclose to all
Koichi Sato, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant PLOS ONE, 9, 12 PLOS ONE, 9, 12 PLOS ONE, 9, 12 2014/12 Refereed English Research paper(scientific journal) Disclose to all
Daisuke Takahashi, Koichi Sato, Mayo Shimomuki, Minoru Takata, Hitoshi Kurumizaka Daisuke Takahashi, Koichi Sato, Mayo Shimomuki, Minoru Takata, Hitoshi Kurumizaka Daisuke Takahashi, Koichi Sato, Mayo Shimomuki, Minoru Takata, Hitoshi Kurumizaka Expression and purification of human FANCI and FANCD2 using Escherichia coli cells Expression and purification of human FANCI and FANCD2 using Escherichia coli cells Expression and purification of human FANCI and FANCD2 using Escherichia coli cells PROTEIN EXPRESSION AND PURIFICATION, 103, 8-15 PROTEIN EXPRESSION AND PURIFICATION, 103, 8-15 PROTEIN EXPRESSION AND PURIFICATION, 103, 8-15 2014/11 Refereed English Research paper(scientific journal) Disclose to all
Kei Ishii, Masamichi Ishiai, Hiroko Morimoto, Mito Kanatsu-Shinohara, Ohtsura Niwa, Minoru Takata, Takashi Shinohara Kei Ishii, Masamichi Ishiai, Hiroko Morimoto, Mito Kanatsu-Shinohara, Ohtsura Niwa, Minoru Takata, Takashi Shinohara Kei Ishii, Masamichi Ishiai, Hiroko Morimoto, Mito Kanatsu-Shinohara, Ohtsura Niwa, Minoru Takata, Takashi Shinohara The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response of Mouse Spermatogonial Stem Cells STEM CELL REPORTS, 3, 4, 676-689 STEM CELL REPORTS, 3, 4, 676-689 STEM CELL REPORTS, 3, 4, 676-689 2014/10 Refereed English Research paper(scientific journal) Disclose to all
Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Modularized Functions of the Fanconi Anemia Core Complex Modularized Functions of the Fanconi Anemia Core Complex Modularized Functions of the Fanconi Anemia Core Complex CELL REPORTS, 7, 6, 1849-1857 CELL REPORTS, 7, 6, 1849-1857 CELL REPORTS, 7, 6, 1849-1857 2014/06 Refereed English Research paper(scientific journal) Disclose to all
Junya Unno, Akiko Itaya, Masato Taoka, Koichi Sato, Junya Tomida, Wataru Sakai, Kaoru Sugasawa, Masamichi Ishiai, Tsuyoshi Ikura, Toshiaki Isobe, Hitoshi Kurumizaka, Minoru Takata Junya Unno, Akiko Itaya, Masato Taoka, Koichi Sato, Junya Tomida, Wataru Sakai, Kaoru Sugasawa, Masamichi Ishiai, Tsuyoshi Ikura, Toshiaki Isobe, Hitoshi Kurumizaka, Minoru Takata Junya Unno, Akiko Itaya, Masato Taoka, Koichi Sato, Junya Tomida, Wataru Sakai, Kaoru Sugasawa, Masamichi Ishiai, Tsuyoshi Ikura, Toshiaki Isobe, Hitoshi Kurumizaka, Minoru Takata FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair CELL REPORTS, 7, 4, 1039-1047 CELL REPORTS, 7, 4, 1039-1047 CELL REPORTS, 7, 4, 1039-1047 2014/05 Refereed English Research paper(scientific journal) Disclose to all
Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, M. Nurul Islam, Hiroshi Arakawa, Weidong Wang, Shunichi Takeda, Yutaka Ishii, Minoru Takata, Masayuki Seki, Takemi Enomoto Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, M. Nurul Islam, Hiroshi Arakawa, Weidong Wang, Shunichi Takeda, Yutaka Ishii, Minoru Takata, Masayuki Seki, Takemi Enomoto Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, M. Nurul Islam, Hiroshi Arakawa, Weidong Wang, Shunichi Takeda, Yutaka Ishii, Minoru Takata, Masayuki Seki, Takemi Enomoto Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1843, 5, 1002-1012 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1843, 5, 1002-1012 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1843, 5, 1002-1012 2014/05 Refereed English Research paper(scientific journal) Disclose to all
Akira Motegi, Minoru Takata Akira Motegi, Minoru Takata Akira Motegi, Minoru Takata Multiple genetic manipulations of DT40 cell line Multiple genetic manipulations of DT40 cell line Multiple genetic manipulations of DT40 cell line Methods in Molecular Biology, 1114, 25-35 Methods in Molecular Biology, 1114, 25-35 Methods in Molecular Biology, 1114, 25-35 2014/01/01 Refereed English Research paper(scientific journal) Disclose to all
Asuka Hira, Hiromasa Yabe, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Jun Nakamura, Seiji Kojima, Seishi Ogawa, Keitaro Matsuo, Minoru Takata, Miharu Yabe Asuka Hira, Hiromasa Yabe, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Jun Nakamura, Seiji Kojima, Seishi Ogawa, Keitaro Matsuo, Minoru Takata, Miharu Yabe Asuka Hira, Hiromasa Yabe, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Jun Nakamura, Seiji Kojima, Seishi Ogawa, Keitaro Matsuo, Minoru Takata, Miharu Yabe Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Blood, 122, 18, 3206-9 Blood, 122, 18, 3206-9 Blood, 122, 18, 3206-9 2013/10/31 Refereed English Research paper(scientific journal) Disclose to all
Hira A, Takata M Hira A, Takata M Hira A, Takata M [Fanconi anemia and the molecular mechanism of the repair of DNA crosslinks Fanconi anemia and the molecular mechanism of the repair of DNA crosslinks. [Fanconi anemia and the molecular mechanism of the repair of DNA crosslinks Rinsho Ketsueki., 54, 10, 1625-1632 Rinsho Ketsueki., 54, 10, 1625-1632 Rinsho Ketsueki., 54, 10, 1625-1632 2013/10 Japanese Disclose to all
Junya Tomida, Akiko Itaya, Tomoko Shigechi, Junya Unno, Emi Uchida, Masae Ikura, Yuji Masuda, Shun Matsuda, Jun Adachi, Masahiko Kobayashi, Amom Ruhikanta Meetei, Yoshihiko Maehara, Ken-ichi Yamamoto, Kenji Kamiya, Akira Matsuura, Tomonari Matsuda, Tsuyoshi Ikura, Masamichi Ishiai, Minoru Takata Junya Tomida, Akiko Itaya, Tomoko Shigechi, Junya Unno, Emi Uchida, Masae Ikura, Yuji Masuda, Shun Matsuda, Jun Adachi, Masahiko Kobayashi, Amom Ruhikanta Meetei, Yoshihiko Maehara, Ken-ichi Yamamoto, Kenji Kamiya, Akira Matsuura, Tomonari Matsuda, Tsuyoshi Ikura, Masamichi Ishiai, Minoru Takata Junya Tomida, Akiko Itaya, Tomoko Shigechi, Junya Unno, Emi Uchida, Masae Ikura, Yuji Masuda, Shun Matsuda, Jun Adachi, Masahiko Kobayashi, Amom Ruhikanta Meetei, Yoshihiko Maehara, Ken-ichi Yamamoto, Kenji Kamiya, Akira Matsuura, Tomonari Matsuda, Tsuyoshi Ikura, Masamichi Ishiai, Minoru Takata A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair NUCLEIC ACIDS RESEARCH, 41, 14, 6930-6941 NUCLEIC ACIDS RESEARCH, 41, 14, 6930-6941 NUCLEIC ACIDS RESEARCH, 41, 14, 6930-6941 2013/08 Refereed English Research paper(scientific journal) Disclose to all
Masahiko Kobayashi, Naoyuki Hayashi, Minoru Takata, Ken-ichi Yamamoto Masahiko Kobayashi, Naoyuki Hayashi, Minoru Takata, Ken-ichi Yamamoto Masahiko Kobayashi, Naoyuki Hayashi, Minoru Takata, Ken-ichi Yamamoto NBS1 directly activates ATR independently of MRE11 and TOPBP1 NBS1 directly activates ATR independently of MRE11 and TOPBP1 NBS1 directly activates ATR independently of MRE11 and TOPBP1 GENES TO CELLS, 18, 3, 238-246 GENES TO CELLS, 18, 3, 238-246 GENES TO CELLS, 18, 3, 238-246 2013/03 Refereed English Research paper(scientific journal) Disclose to all
Daisuke Minami, Nagio Takigawa, Hiromasa Takeda, Minoru Takata, Nobuaki Ochi, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura Daisuke Minami, Nagio Takigawa, Hiromasa Takeda, Minoru Takata, Nobuaki Ochi, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura Daisuke Minami, Nagio Takigawa, Hiromasa Takeda, Minoru Takata, Nobuaki Ochi, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells Molecular Cancer Research, 11, 2, 140-148 Molecular Cancer Research, 11, 2, 140-148 Molecular Cancer Research, 11, 2, 140-148 2013/02 Refereed English Research paper(scientific journal) Disclose to all
髙田 穰 髙田 穰 染色体脆弱部位の複製とDNA損傷ストレス応答のメカニズム 染色体脆弱部位の複製とDNA損傷ストレス応答のメカニズム 実験医学 実験医学 2012/09 Japanese Disclose to all
Kohei Nishimura, Masamichi Ishiai, Kazuki Horikawa, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato T. Kanemaki Kohei Nishimura, Masamichi Ishiai, Kazuki Horikawa, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato T. Kanemaki Kohei Nishimura, Masamichi Ishiai, Kazuki Horikawa, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato T. Kanemaki Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Cross links Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Cross links Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Cross links MOLECULAR CELL, 47, 4, 511-522 MOLECULAR CELL, 47, 4, 511-522 MOLECULAR CELL, 47, 4, 511-522 2012/08 Refereed English Research paper(scientific journal) Disclose to all
Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair EMBO JOURNAL, 31, 17, 3524-3536 EMBO JOURNAL, 31, 17, 3524-3536 EMBO JOURNAL, 31, 17, 3524-3536 2012/08 Refereed English Research paper(scientific journal) Disclose to all
Zhijiang Yan, Rong Guo, Manikandan Paramasivam, Weiping Shen, Chen Ling, David Fox, Yucai Wang, Anneke B. Oostra, Julia Kuehl, Duck-Yeon Lee, Minoru Takata, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Lei Li, Michael M. Seidman, Weidong Wang Zhijiang Yan, Rong Guo, Manikandan Paramasivam, Weiping Shen, Chen Ling, David Fox, Yucai Wang, Anneke B. Oostra, Julia Kuehl, Duck-Yeon Lee, Minoru Takata, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Lei Li, Michael M. Seidman, Weidong Wang Zhijiang Yan, Rong Guo, Manikandan Paramasivam, Weiping Shen, Chen Ling, David Fox, Yucai Wang, Anneke B. Oostra, Julia Kuehl, Duck-Yeon Lee, Minoru Takata, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Lei Li, Michael M. Seidman, Weidong Wang A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network MOLECULAR CELL, 47, 1, 61-75 MOLECULAR CELL, 47, 1, 61-75 MOLECULAR CELL, 47, 1, 61-75 2012/07 Refereed English Research paper(scientific journal) Disclose to all
Miharu Yabe, Takashi Shimizu, Tsuyoshi Morimoto, Takashi Koike, Hiromitsu Takakura, Hideo Tsukamoto, Kazuo Muroi, Koichi Oshima, Keiko Asami, Minoru Takata, Takayuki Yamashita, Shunichi Kato, Hiromasa Yabe Miharu Yabe, Takashi Shimizu, Tsuyoshi Morimoto, Takashi Koike, Hiromitsu Takakura, Hideo Tsukamoto, Kazuo Muroi, Koichi Oshima, Keiko Asami, Minoru Takata, Takayuki Yamashita, Shunichi Kato, Hiromasa Yabe Miharu Yabe, Takashi Shimizu, Tsuyoshi Morimoto, Takashi Koike, Hiromitsu Takakura, Hideo Tsukamoto, Kazuo Muroi, Koichi Oshima, Keiko Asami, Minoru Takata, Takayuki Yamashita, Shunichi Kato, Hiromasa Yabe Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism PEDIATRIC TRANSPLANTATION, 16, 4, 340-345 PEDIATRIC TRANSPLANTATION, 16, 4, 340-345 PEDIATRIC TRANSPLANTATION, 16, 4, 340-345 2012/06 Refereed English Research paper(scientific journal) Disclose to all
Koichi Sato, Kazue Toda, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Kazue Toda, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Kazue Toda, Masamichi Ishiai, Minoru Takata, Hitoshi Kurumizaka DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI NUCLEIC ACIDS RESEARCH, 40, 10, 4553-4561 NUCLEIC ACIDS RESEARCH, 40, 10, 4553-4561 NUCLEIC ACIDS RESEARCH, 40, 10, 4553-4561 2012/05 Refereed English Research paper(scientific journal) Disclose to all
Kelly A. Hoadley, Yutong Xue, Chen Ling, Minoru Takata, Weidong Wang, James L. Keck Kelly A. Hoadley, Yutong Xue, Chen Ling, Minoru Takata, Weidong Wang, James L. Keck Kelly A. Hoadley, Yutong Xue, Chen Ling, Minoru Takata, Weidong Wang, James L. Keck Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 12, 4437-4442 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 12, 4437-4442 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 12, 4437-4442 2012/03 Refereed English Research paper(scientific journal) Disclose to all
Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, Munkhbold Tuul, Ryo Sakasai, Keiji Yoshinaga, Hiroshi Saeki, Masaru Morita, Yoshihiro Kakeji, David A Gillespie, Ken-Ichi Yamamoto, Minoru Takata, Hiroyuki Kitao, Yoshihiko Maehara Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, Munkhbold Tuul, Ryo Sakasai, Keiji Yoshinaga, Hiroshi Saeki, Masaru Morita, Yoshihiro Kakeji, David A Gillespie, Ken-Ichi Yamamoto, Minoru Takata, Hiroyuki Kitao, Yoshihiko Maehara Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, Munkhbold Tuul, Ryo Sakasai, Keiji Yoshinaga, Hiroshi Saeki, Masaru Morita, Yoshihiro Kakeji, David A Gillespie, Ken-Ichi Yamamoto, Minoru Takata, Hiroyuki Kitao, Yoshihiko Maehara ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity. DNA repair, 11, 3, 247-58 DNA repair, 11, 3, 247-58 DNA repair, 11, 3, 247-58 2012/03/01 Refereed English Research paper(scientific journal) Disclose to all
Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John K. Eykelenboom, Fabio Pessina, Yanbin Zhang, Emi Uchida, Masamichi Ishiai, Noel F. Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John K. Eykelenboom, Fabio Pessina, Yanbin Zhang, Emi Uchida, Masamichi Ishiai, Noel F. Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John K. Eykelenboom, Fabio Pessina, Yanbin Zhang, Emi Uchida, Masamichi Ishiai, Noel F. Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway CANCER RESEARCH, 72, 5, 1149-1156 CANCER RESEARCH, 72, 5, 1149-1156 CANCER RESEARCH, 72, 5, 1149-1156 2012/03 Refereed English Research paper(scientific journal) Disclose to all
石合正道, 髙田穣 石合正道, 髙田穣 ゲノムDNA 損傷応答ネットワーク解明の新展開 ゲノムDNA 損傷応答ネットワーク解明の新展開 メディカル・サイエンス・ダイジェ スト 特集「DNA 損傷応答ネットワークと疾患」特集編輯 髙田穣,38(1), 14-16,2012 メディカル・サイエンス・ダイジェ スト 特集「DNA 損傷応答ネットワークと疾患」特集編輯 髙田穣,38(1), 14-16,2012 2012 Refereed Japanese Disclose to all
Masamichi Ishiai, Emi Uchida, Minoru Takata Masamichi Ishiai, Emi Uchida, Minoru Takata Masamichi Ishiai, Emi Uchida, Minoru Takata Establishment of the DNA repair-defective mutants in DT40 cells Establishment of the DNA repair-defective mutants in DT40 cells Establishment of the DNA repair-defective mutants in DT40 cells Methods in Molecular Biology, 920, 39-49 Methods in Molecular Biology, 920, 39-49 Methods in Molecular Biology, 920, 39-49 2012 Refereed English Research paper(scientific journal) Disclose to all
Ivan V. Rosado, Frédéric Langevin, Gerry P. Crossan, Minoru Takata, Ketan J. Patel Ivan V. Rosado, Frédéric Langevin, Gerry P. Crossan, Minoru Takata, Ketan J. Patel Ivan V. Rosado, Frédéric Langevin, Gerry P. Crossan, Minoru Takata, Ketan J. Patel Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway Nature Structural and Molecular Biology, 18, 12, 1432-1434 Nature Structural and Molecular Biology, 18, 12, 1432-1434 Nature Structural and Molecular Biology, 18, 12, 1432-1434 2011/12 Refereed English Research paper(scientific journal) Disclose to all
Daphne W. Bell, Nilabja Sikdar, Kyoo-young Lee, Jessica C. Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L. Rudd, Lana M. Pollock, Sarah K. Fogoros, Hassan Mohamed, Christin L. Hanigan, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F. Hansen, Praveen F. Cherukuri, Bhavesh Borate, Kirk J. McManus, Jan Stoepel, Payal Sipahimalani, Andrew K. Godwin, Dennis C. Sgroi, Maria J. Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C. Mullikin, Tyra G. Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung Daphne W. Bell, Nilabja Sikdar, Kyoo-young Lee, Jessica C. Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L. Rudd, Lana M. Pollock, Sarah K. Fogoros, Hassan Mohamed, Christin L. Hanigan, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F. Hansen, Praveen F. Cherukuri, Bhavesh Borate, Kirk J. McManus, Jan Stoepel, Payal Sipahimalani, Andrew K. Godwin, Dennis C. Sgroi, Maria J. Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C. Mullikin, Tyra G. Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung Daphne W. Bell, Nilabja Sikdar, Kyoo-young Lee, Jessica C. Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L. Rudd, Lana M. Pollock, Sarah K. Fogoros, Hassan Mohamed, Christin L. Hanigan, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F. Hansen, Praveen F. Cherukuri, Bhavesh Borate, Kirk J. McManus, Jan Stoepel, Payal Sipahimalani, Andrew K. Godwin, Dennis C. Sgroi, Maria J. Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C. Mullikin, Tyra G. Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 PLOS GENETICS, 7, 8 PLOS GENETICS, 7, 8 PLOS GENETICS, 7, 8 2011/08 Refereed English Research paper(scientific journal) Disclose to all
Nobuko Matsushita, Yujiro Endo, Koichi Sato, Hitoshi Kurumizaka, Takayuki Yamashita, Minoru Takata, Shigeru Yanagi Matsushita N, Endo Y, Sato K, Kurumizaka H, Yamashita T, Takata M, Yanagi S Nobuko Matsushita, Yujiro Endo, Koichi Sato, Hitoshi Kurumizaka, Takayuki Yamashita, Minoru Takata, Shigeru Yanagi Direct Inhibition of TNF-alpha Promoter Activity by Fanconi Anemia Protein FANCD2 Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2. Direct Inhibition of TNF-alpha Promoter Activity by Fanconi Anemia Protein FANCD2 PLOS ONE, 6, 8, e23324 PloS one, 6, 8, e23324 PLOS ONE, 6, 8, e23324 2011/08 Refereed English Research paper(scientific journal) Disclose to all
Jean-Hugues Guervilly, Emilie Renaud, Minoru Takata, Filippo Rosselli Jean-Hugues Guervilly, Emilie Renaud, Minoru Takata, Filippo Rosselli Jean-Hugues Guervilly, Emilie Renaud, Minoru Takata, Filippo Rosselli USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation HUMAN MOLECULAR GENETICS, 20, 11, 2171-2181 HUMAN MOLECULAR GENETICS, 20, 11, 2171-2181 HUMAN MOLECULAR GENETICS, 20, 11, 2171-2181 2011/06 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Kitao, Indrajit Nanda, Ryuichi P. Sugino, Aiko Kinomura, Mitsuyoshi Yamazoe, Hiroshi Arakawa, Michael Schmid, Hideki Innan, Kevin Hiom, Minoru Takata Hiroyuki Kitao, Indrajit Nanda, Ryuichi P. Sugino, Aiko Kinomura, Mitsuyoshi Yamazoe, Hiroshi Arakawa, Michael Schmid, Hideki Innan, Kevin Hiom, Minoru Takata Hiroyuki Kitao, Indrajit Nanda, Ryuichi P. Sugino, Aiko Kinomura, Mitsuyoshi Yamazoe, Hiroshi Arakawa, Michael Schmid, Hideki Innan, Kevin Hiom, Minoru Takata FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells GENES TO CELLS, 16, 6, 714-727 GENES TO CELLS, 16, 6, 714-727 GENES TO CELLS, 16, 6, 714-727 2011/06 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Kitao, Minoru Takata Hiroyuki Kitao, Minoru Takata Hiroyuki Kitao, Minoru Takata Fanconi anemia: a disorder defective in the DNA damage response Fanconi anemia: a disorder defective in the DNA damage response Fanconi anemia: a disorder defective in the DNA damage response INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 417-424 INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 417-424 INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 417-424 2011/04 Refereed English Research paper(scientific journal) Disclose to all
Minoru Takata Minoru Takata Minoru Takata Fanconi anemia and the DNA damage response Fanconi anemia and the DNA damage response Fanconi anemia and the DNA damage response INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 415-416 INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 415-416 INTERNATIONAL JOURNAL OF HEMATOLOGY, 93, 4, 415-416 2011/04 Refereed English Disclose to all
Kimiyo N. Yamamoto, Shunsuke Kobayashi, Masataka Tsuda, Hitoshi Kurumizaka, Minoru Takata, Koichi Kono, Josef Jiricny, Shunichi Takeda, Kouji Hirota Kimiyo N. Yamamoto, Shunsuke Kobayashi, Masataka Tsuda, Hitoshi Kurumizaka, Minoru Takata, Koichi Kono, Josef Jiricny, Shunichi Takeda, Kouji Hirota Kimiyo N. Yamamoto, Shunsuke Kobayashi, Masataka Tsuda, Hitoshi Kurumizaka, Minoru Takata, Koichi Kono, Josef Jiricny, Shunichi Takeda, Kouji Hirota Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 16, 6492-6496 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 16, 6492-6496 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108, 16, 6492-6496 2011/04 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Kitao, Seiki Hirano, Minoru Takata Hiroyuki Kitao, Seiki Hirano, Minoru Takata Hiroyuki Kitao, Seiki Hirano, Minoru Takata Evaluation of Homologous Recombinational Repair in Chicken B Lymphoma Cell Line, DT40 Evaluation of Homologous Recombinational Repair in Chicken B Lymphoma Cell Line, DT40 Evaluation of Homologous Recombinational Repair in Chicken B Lymphoma Cell Line, DT40 Methods in Molecular Biology, 745, 293-309 Methods in Molecular Biology, 745, 293-309 Methods in Molecular Biology, 745, 293-309 2011/04 Refereed English Research paper(scientific journal) Disclose to all
Kazunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda, Josef Jiricny Kazunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda, Josef Jiricny Kazunori Yoshikiyo, Katja Kratz, Kouji Hirota, Kana Nishihara, Minoru Takata, Hitoshi Kurumizaka, Satoshi Horimoto, Shunichi Takeda, Josef Jiricny KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107, 50, 21553-21557 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107, 50, 21553-21557 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107, 50, 21553-21557 2010/12 Refereed English Research paper(scientific journal) Disclose to all
茂地 智子, 高田 穣 茂地 智子, 高田 穣 ファンコニ貧血原因遺伝子群の機能と調節機構 ファンコニ貧血原因遺伝子群の機能と調節機構 G.I.Resarch (Journal of Gastrointestinal Research)特集/DNA修復機能異常と疾患 G.I.Resarch (Journal of Gastrointestinal Research)特集/DNA修復機能異常と疾患 2010/04 Japanese Disclose to all
板谷亜希子, 高田穣 板谷亜希子, 高田穣 ファンコニ貧血の分子メカニズム ファンコニ貧血の分子メカニズム 血液診療エキスパート:貧血』中外医学社 215-17 血液診療エキスパート:貧血』中外医学社 215-17 2010/02 Japanese Disclose to all
冨田純也, 高田 穣 冨田純也, 高田 穣 DNAクロスリンク損傷修復の分子機構 DNAクロスリンク損傷修復の分子機構 細胞工学 特集号 細胞工学 特集号 2010/01 Refereed Japanese Disclose to all
板谷亜希子, 高田 穣 板谷亜希子, 高田 穣 Fanconi貧血におけるゲノム不安定性メカニズム Fanconi貧血におけるゲノム不安定性メカニズム 臨床血液 51:546-552 臨床血液 51:546-552 2010 Refereed Japanese Disclose to all
Kadoaki Ohashi, Nagio Takigawa, Masahiro Osawa, Eiki Ichihara, Hiromasa Takeda, Toshio Kubo, Seiki Hirano, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Kadoaki Ohashi, Nagio Takigawa, Masahiro Osawa, Eiki Ichihara, Hiromasa Takeda, Toshio Kubo, Seiki Hirano, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Kadoaki Ohashi, Nagio Takigawa, Masahiro Osawa, Eiki Ichihara, Hiromasa Takeda, Toshio Kubo, Seiki Hirano, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Chemopreventive Effects of Gefitinib on Nonsmoking-Related Lung Tumorigenesis in Activating Epidermal Growth Factor Receptor Transgenic Mice Chemopreventive Effects of Gefitinib on Nonsmoking-Related Lung Tumorigenesis in Activating Epidermal Growth Factor Receptor Transgenic Mice Chemopreventive Effects of Gefitinib on Nonsmoking-Related Lung Tumorigenesis in Activating Epidermal Growth Factor Receptor Transgenic Mice CANCER RESEARCH, 69, 17, 7088-7095 CANCER RESEARCH, 69, 17, 7088-7095 CANCER RESEARCH, 69, 17, 7088-7095 2009/09 Refereed English Research paper(scientific journal) Disclose to all
Minoru Takata, Masamichi Ishiai, Hiroyuki Kitao Minoru Takata, Masamichi Ishiai, Hiroyuki Kitao Minoru Takata, Masamichi Ishiai, Hiroyuki Kitao The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 668, 1-2, 92-102 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 668, 1-2, 92-102 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 668, 1-2, 92-102 2009/07 Refereed English Disclose to all
松下暢子, 北尾洋之, 石合正道, 髙田穣 松下暢子, 北尾洋之, 石合正道, 髙田穣 ファンコニ貧血とDNA損傷応答ネットワーク(染色体サイクル ゲノムの恒常性維持、継承とダイナミクス) ファンコニ貧血とDNA損傷応答ネットワーク(染色体サイクル ゲノムの恒常性維持、継承とダイナミクス) 蛋白質核酸酵素54(4)580-585 蛋白質核酸酵素54(4)580-585 2009/03 Japanese Disclose to all
松下暢子, 北尾洋之, 石合正道, 高田穣 松下暢子, 北尾洋之, 石合正道, 高田穣 ファンコニ貧血とDNA損傷応答ネットワーク ファンコニ貧血とDNA損傷応答ネットワーク 蛋白質核酸酵素 増刊 染色体サイクル ゲノムの恒常性維持、継承とダイナミクス 編集 正井久雄 舛方久夫 釣本敏樹 篠原彰 蛋白質核酸酵素 増刊 染色体サイクル ゲノムの恒常性維持、継承とダイナミクス 編集 正井久雄 舛方久夫 釣本敏樹 篠原彰 2009/03 Japanese Disclose to all
N. Matsushita, H. Kitao, M. Ishiai, M. Takata N. Matsushita, H. Kitao, M. Ishiai, M. Takata N. Matsushita, H. Kitao, M. Ishiai, M. Takata [Fanconi anemia and DNA-damage response network]. [Fanconi anemia and DNA-damage response network]. [Fanconi anemia and DNA-damage response network]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 580-585 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 580-585 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 580-585 2009 Refereed English Disclose to all
Takuya Abe, Masamichi Ishiai, Yoshifumi Hosono, Akari Yoshimura, Shusuke Tada, Noritaka Adachi, Hideki Koyama, Minoru Takata, Shunichi Takeda, Takemi Enomoto, Masayuki Seki Takuya Abe, Masamichi Ishiai, Yoshifumi Hosono, Akari Yoshimura, Shusuke Tada, Noritaka Adachi, Hideki Koyama, Minoru Takata, Shunichi Takeda, Takemi Enomoto, Masayuki Seki Takuya Abe, Masamichi Ishiai, Yoshifumi Hosono, Akari Yoshimura, Shusuke Tada, Noritaka Adachi, Hideki Koyama, Minoru Takata, Shunichi Takeda, Takemi Enomoto, Masayuki Seki KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation CELLULAR SIGNALLING, 20, 11, 1978-1985 CELLULAR SIGNALLING, 20, 11, 1978-1985 CELLULAR SIGNALLING, 20, 11, 1978-1985 2008/11 Refereed English Research paper(scientific journal) Disclose to all
Masamichi Ishiai, Hiroyuki Kitao, Agata Smogorzewska, Junya Tomida, Aiko Kinomura, Emi Uchida, Alihossein Saberi, Eiji Kinoshita, Emiko Kinoshita-Kikuta, Tohru Koike, Satoshi Tashiro, Stephen J. Elledge, Minoru Takata Masamichi Ishiai, Hiroyuki Kitao, Agata Smogorzewska, Junya Tomida, Aiko Kinomura, Emi Uchida, Alihossein Saberi, Eiji Kinoshita, Emiko Kinoshita-Kikuta, Tohru Koike, Satoshi Tashiro, Stephen J. Elledge, Minoru Takata Masamichi Ishiai, Hiroyuki Kitao, Agata Smogorzewska, Junya Tomida, Aiko Kinomura, Emi Uchida, Alihossein Saberi, Eiji Kinoshita, Emiko Kinoshita-Kikuta, Tohru Koike, Satoshi Tashiro, Stephen J. Elledge, Minoru Takata FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway NATURE STRUCTURAL & MOLECULAR BIOLOGY, 15, 11, 1138-1146 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 15, 11, 1138-1146 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 15, 11, 1138-1146 2008/11 Refereed English Research paper(scientific journal) Disclose to all
Kadoaki Ohashi, Kammei Rai, Yoshiro Fujiwara, Masahiro Osawa, Seiki Hirano, Katsuyoshi Takata, Eisaku Kondo, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Kadoaki Ohashi, Kammei Rai, Yoshiro Fujiwara, Masahiro Osawa, Seiki Hirano, Katsuyoshi Takata, Eisaku Kondo, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Kadoaki Ohashi, Kammei Rai, Yoshiro Fujiwara, Masahiro Osawa, Seiki Hirano, Katsuyoshi Takata, Eisaku Kondo, Tadashi Yoshino, Minoru Takata, Mitsune Tanimoto, Katsuyuki Kiura Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter. Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter. Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter. Cancer science, 99, 9, 1747-53 Cancer science, 99, 9, 1747-53 Cancer science, 99, 9, 1747-53 2008/09 Refereed English Research paper(scientific journal) Disclose to all
P. Uma Devi, H. Utsumi, M. Takata, S. Takeda P. Uma Devi, H. Utsumi, M. Takata, S. Takeda P. Uma Devi, H. Utsumi, M. Takata, S. Takeda Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 46, 6, 437-442 INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 46, 6, 437-442 INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 46, 6, 437-442 2008/06 Refereed English Research paper(scientific journal) Disclose to all
J. B. Wilson, K. Yamamoto, A. S. Marriott, S. Hussain, P. Sung, M. E. Hoatlin, C. G. Mathew, M. Takata, L. H. Thompson, G. M. Kupfer, N. J. Jones J. B. Wilson, K. Yamamoto, A. S. Marriott, S. Hussain, P. Sung, M. E. Hoatlin, C. G. Mathew, M. Takata, L. H. Thompson, G. M. Kupfer, N. J. Jones J. B. Wilson, K. Yamamoto, A. S. Marriott, S. Hussain, P. Sung, M. E. Hoatlin, C. G. Mathew, M. Takata, L. H. Thompson, G. M. Kupfer, N. J. Jones FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 ONCOGENE, 27, 26, 3641-3652 ONCOGENE, 27, 26, 3641-3652 ONCOGENE, 27, 26, 3641-3652 2008/06 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Kitao, Masayo Kimura, Kazuhiko Yamamoto, Hidetaka Seo, Keiko Namikoshi, Yasutoshi Agata, Kunihiro Ohta, Minoru Takata Hiroyuki Kitao, Masayo Kimura, Kazuhiko Yamamoto, Hidetaka Seo, Keiko Namikoshi, Yasutoshi Agata, Kunihiro Ohta, Minoru Takata Hiroyuki Kitao, Masayo Kimura, Kazuhiko Yamamoto, Hidetaka Seo, Keiko Namikoshi, Yasutoshi Agata, Kunihiro Ohta, Minoru Takata Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion INTERNATIONAL IMMUNOLOGY, 20, 2, 277-284 INTERNATIONAL IMMUNOLOGY, 20, 2, 277-284 INTERNATIONAL IMMUNOLOGY, 20, 2, 277-284 2008/02 Refereed English Research paper(scientific journal) Disclose to all
Tomida, J, Kitao, H, Kinoshita, E, Takata, M Tomida, J, Kitao, H, Kinoshita, E, Takata, M Tomida, J, Kitao, H, Kinoshita, E, Takata, M Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel. Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel. Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel. Nature Protocols doi:10.1038/nprot.232 Nature Protocols doi:10.1038/nprot.232 Nature Protocols doi:10.1038/nprot.232 2008 Refereed English Research paper(scientific journal) Disclose to all
John R. Ridpath, Ayumi Nakamura, Keizo Tano, April M. Luke, Eiichiro Sonoda, Hiroshi Arakawa, Jean-Marie Buerstedde, David A. F. Gillespie, Julian E. Sale, Mitsuyoshi Yamazoe, Douglas K. Bishop, Minoru Takata, Shunichi Takeda, Masami Watanabe, James A. Swenberg, Jun Nakamura John R. Ridpath, Ayumi Nakamura, Keizo Tano, April M. Luke, Eiichiro Sonoda, Hiroshi Arakawa, Jean-Marie Buerstedde, David A. F. Gillespie, Julian E. Sale, Mitsuyoshi Yamazoe, Douglas K. Bishop, Minoru Takata, Shunichi Takeda, Masami Watanabe, James A. Swenberg, Jun Nakamura John R. Ridpath, Ayumi Nakamura, Keizo Tano, April M. Luke, Eiichiro Sonoda, Hiroshi Arakawa, Jean-Marie Buerstedde, David A. F. Gillespie, Julian E. Sale, Mitsuyoshi Yamazoe, Douglas K. Bishop, Minoru Takata, Shunichi Takeda, Masami Watanabe, James A. Swenberg, Jun Nakamura Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde CANCER RESEARCH, 67, 23, 11117-11122 CANCER RESEARCH, 67, 23, 11117-11122 CANCER RESEARCH, 67, 23, 11117-11122 2007/12 Refereed English Research paper(scientific journal) Disclose to all
Lydia Messaoudi, Yun-Gui Yang, Aiko Kinomura, Diana A. Stavreva, Gonghong Yan, Marie-Line Bortolin-Cavaille, Hiroshi Arakawa, Jean-Marie Buerstedde, Pierre Hainaut, Jerome Cavaille, Minoru Takata, Eric Van Dyck Lydia Messaoudi, Yun-Gui Yang, Aiko Kinomura, Diana A. Stavreva, Gonghong Yan, Marie-Line Bortolin-Cavaille, Hiroshi Arakawa, Jean-Marie Buerstedde, Pierre Hainaut, Jerome Cavaille, Minoru Takata, Eric Van Dyck Lydia Messaoudi, Yun-Gui Yang, Aiko Kinomura, Diana A. Stavreva, Gonghong Yan, Marie-Line Bortolin-Cavaille, Hiroshi Arakawa, Jean-Marie Buerstedde, Pierre Hainaut, Jerome Cavaille, Minoru Takata, Eric Van Dyck Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress NUCLEIC ACIDS RESEARCH, 35, 19, 6571-6587 NUCLEIC ACIDS RESEARCH, 35, 19, 6571-6587 NUCLEIC ACIDS RESEARCH, 35, 19, 6571-6587 2007/10 Refereed English Research paper(scientific journal) Disclose to all
Hiroshi Suehisa, Shinichi Toyooka, Katsuyuki Hotta, Akiko Uchida, Junichi Soh, Yoshiro Fujiwara, Keitaro Matsuo, Mamoru Ouchida, Minoru Takata, Katsuyuki Kiura, Hiroshi Date Hiroshi Suehisa, Shinichi Toyooka, Katsuyuki Hotta, Akiko Uchida, Junichi Soh, Yoshiro Fujiwara, Keitaro Matsuo, Mamoru Ouchida, Minoru Takata, Katsuyuki Kiura, Hiroshi Date Hiroshi Suehisa, Shinichi Toyooka, Katsuyuki Hotta, Akiko Uchida, Junichi Soh, Yoshiro Fujiwara, Keitaro Matsuo, Mamoru Ouchida, Minoru Takata, Katsuyuki Kiura, Hiroshi Date Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung Epidermal growth factor receptor mutation status and adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung JOURNAL OF CLINICAL ONCOLOGY, 25, 25, 3952-3957 JOURNAL OF CLINICAL ONCOLOGY, 25, 25, 3952-3957 JOURNAL OF CLINICAL ONCOLOGY, 25, 25, 3952-3957 2007/09 Refereed English Research paper(scientific journal) Disclose to all
Atsuko Ogino, Hiroyuki Kitao, Seiki Hirano, Akiko Uchida, Masamichi Ishiai, Toshiyuki Kozuki, Nagio Takigawa, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Atsuko Ogino, Hiroyuki Kitao, Seiki Hirano, Akiko Uchida, Masamichi Ishiai, Toshiyuki Kozuki, Nagio Takigawa, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Atsuko Ogino, Hiroyuki Kitao, Seiki Hirano, Akiko Uchida, Masamichi Ishiai, Toshiyuki Kozuki, Nagio Takigawa, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line CANCER RESEARCH, 67, 16, 7807-7814 CANCER RESEARCH, 67, 16, 7807-7814 CANCER RESEARCH, 67, 16, 7807-7814 2007/08 Refereed English Research paper(scientific journal) Disclose to all
Chen Ling, Masamichi Ishiai, Abdullah Mahmood Ali, Annette L. Medhurst, Kornelia Neveling, Reinhard Kalb, Zhijiang Yan, Yutong Xue, Anneke B. Oostra, Arleen D. Auerbach, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Minoru Takata, Amom Ruhikanta Meetei, Weidong Wang Chen Ling, Masamichi Ishiai, Abdullah Mahmood Ali, Annette L. Medhurst, Kornelia Neveling, Reinhard Kalb, Zhijiang Yan, Yutong Xue, Anneke B. Oostra, Arleen D. Auerbach, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Minoru Takata, Amom Ruhikanta Meetei, Weidong Wang Chen Ling, Masamichi Ishiai, Abdullah Mahmood Ali, Annette L. Medhurst, Kornelia Neveling, Reinhard Kalb, Zhijiang Yan, Yutong Xue, Anneke B. Oostra, Arleen D. Auerbach, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Minoru Takata, Amom Ruhikanta Meetei, Weidong Wang FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway EMBO JOURNAL, 26, 8, 2104-2114 EMBO JOURNAL, 26, 8, 2104-2114 EMBO JOURNAL, 26, 8, 2104-2114 2007/04 Refereed English Research paper(scientific journal) Disclose to all
Shinichi Toyooka, Akiko Uchida, Hisayuki Shigematsu, Junichi Soh, Atsuko Ogino, Minoru Takata, Katsuyuki Kiura, Mamoru Ouchida, Takayuki Kosaka, Motoi Aoe, Tetsuya Mitsudomi, Hiroshi Date Shinichi Toyooka, Akiko Uchida, Hisayuki Shigematsu, Junichi Soh, Atsuko Ogino, Minoru Takata, Katsuyuki Kiura, Mamoru Ouchida, Takayuki Kosaka, Motoi Aoe, Tetsuya Mitsudomi, Hiroshi Date Shinichi Toyooka, Akiko Uchida, Hisayuki Shigematsu, Junichi Soh, Atsuko Ogino, Minoru Takata, Katsuyuki Kiura, Mamoru Ouchida, Takayuki Kosaka, Motoi Aoe, Tetsuya Mitsudomi, Hiroshi Date The effect of gefitinib on B-RAF mutant non-small cell lung cancer and transfectants The effect of gefitinib on B-RAF mutant non-small cell lung cancer and transfectants The effect of gefitinib on B-RAF mutant non-small cell lung cancer and transfectants Journal of Thoracic Oncology, 2, 4, 321-324 Journal of Thoracic Oncology, 2, 4, 321-324 Journal of Thoracic Oncology, 2, 4, 321-324 2007/04 Refereed English Research paper(scientific journal) Disclose to all
Sohsuke Seki, Mioko Ohzeki, Akiko Uchida, Seiki Hirano, Nobuko Matsushita, Hiroyuki Kitao, Tsukasa Oda, Takayuki Yamashita, Naoki Kashihara, Akio Tsubahara, Minoru Takata, Masamichi Ishiai Sohsuke Seki, Mioko Ohzeki, Akiko Uchida, Seiki Hirano, Nobuko Matsushita, Hiroyuki Kitao, Tsukasa Oda, Takayuki Yamashita, Naoki Kashihara, Akio Tsubahara, Minoru Takata, Masamichi Ishiai Sohsuke Seki, Mioko Ohzeki, Akiko Uchida, Seiki Hirano, Nobuko Matsushita, Hiroyuki Kitao, Tsukasa Oda, Takayuki Yamashita, Naoki Kashihara, Akio Tsubahara, Minoru Takata, Masamichi Ishiai A requirement of FancL and FancD2 monoubiquitination in DNA repair A requirement of FancL and FancD2 monoubiquitination in DNA repair A requirement of FancL and FancD2 monoubiquitination in DNA repair GENES TO CELLS, 12, 3, 299-310 GENES TO CELLS, 12, 3, 299-310 GENES TO CELLS, 12, 3, 299-310 2007/03 Refereed English Research paper(scientific journal) Disclose to all
M. Takata, H. Kitao, M. Ishiai M. Takata, H. Kitao, M. Ishiai M. Takata, H. Kitao, M. Ishiai Fanconi anemia: genetic analysis of a human disease using chicken system Fanconi anemia: genetic analysis of a human disease using chicken system Fanconi anemia: genetic analysis of a human disease using chicken system CYTOGENETIC AND GENOME RESEARCH, 117, 1-4, 346-351 CYTOGENETIC AND GENOME RESEARCH, 117, 1-4, 346-351 CYTOGENETIC AND GENOME RESEARCH, 117, 1-4, 346-351 2007 Refereed English Research paper(scientific journal) Disclose to all
Kuniyoshi Iwabuchi, Mitsumasa Hashimoto, Tadashi Matsui, Takayuki Kurihara, Hiroko Shimizu, Noritaka Adachi, Masamichi Ishiai, Ken-Ichi Yamamoto, Hiroshi Tauchi, Minoru Takata, Hideki Koyama, Takayasu Date Kuniyoshi Iwabuchi, Mitsumasa Hashimoto, Tadashi Matsui, Takayuki Kurihara, Hiroko Shimizu, Noritaka Adachi, Masamichi Ishiai, Ken-Ichi Yamamoto, Hiroshi Tauchi, Minoru Takata, Hideki Koyama, Takayasu Date Kuniyoshi Iwabuchi, Mitsumasa Hashimoto, Tadashi Matsui, Takayuki Kurihara, Hiroko Shimizu, Noritaka Adachi, Masamichi Ishiai, Ken-Ichi Yamamoto, Hiroshi Tauchi, Minoru Takata, Hideki Koyama, Takayasu Date 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis Genes to Cells, 11, 8, 935-948 Genes to Cells, 11, 8, 935-948 Genes to Cells, 11, 8, 935-948 2006/08 Refereed English Research paper(scientific journal) Disclose to all
Hiroyuki Kitao, Kazuhiko Yamamoto, Nobuko Matsushita, Mioko Ohzeki, Masamichi Ishiai, Minoru Takata Hiroyuki Kitao, Kazuhiko Yamamoto, Nobuko Matsushita, Mioko Ohzeki, Masamichi Ishiai, Minoru Takata Hiroyuki Kitao, Kazuhiko Yamamoto, Nobuko Matsushita, Mioko Ohzeki, Masamichi Ishiai, Minoru Takata Functional interplay between BRCA2/FancD1 and FancC in DNA repair Functional interplay between BRCA2/FancD1 and FancC in DNA repair Functional interplay between BRCA2/FancD1 and FancC in DNA repair JOURNAL OF BIOLOGICAL CHEMISTRY, 281, 30, 21312-21320 JOURNAL OF BIOLOGICAL CHEMISTRY, 281, 30, 21312-21320 JOURNAL OF BIOLOGICAL CHEMISTRY, 281, 30, 21312-21320 2006/07 Refereed English Research paper(scientific journal) Disclose to all
Kitao H, Takata M Kitao H, Takata M Kitao H, Takata M Purification of TAP-tagged proteins by two-step pull down from DT40 cells. Purification of TAP-tagged proteins by two-step pull down from DT40 cells. Purification of TAP-tagged proteins by two-step pull down from DT40 cells. Sub-cellular biochemistry, 40, 409-413 Sub-cellular biochemistry, 40, 409-413 Sub-cellular biochemistry, 40, 409-413 2006 Refereed Disclose to all
M. Takata, K. Yamamoto, N. Matsushita, H. Kitao, S. Hirano, M. Ishiai M. Takata, K. Yamamoto, N. Matsushita, H. Kitao, S. Hirano, M. Ishiai M. Takata, K. Yamamoto, N. Matsushita, H. Kitao, S. Hirano, M. Ishiai The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line. The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line. The fanconi anemia pathway promotes homologous recombination repair in DT40 cell line. Sub-cellular biochemistry, 40, 295-311 Sub-cellular biochemistry, 40, 295-311 Sub-cellular biochemistry, 40, 295-311 2006 Refereed English Disclose to all
K Nojima, H Hochegger, A Saberi, T Fukushima, K Kikuchi, M Yoshimura, BJ Orelli, DK Bishop, S Hirano, M Ohzeki, M Ishiai, K Yamamoto, M Takata, H Arakawa, JM Buerstedde, M Yamazoe, T Kawamoto, K Araki, JA Takahashi, N Hashimoto, S Takeda, E Sonoda K Nojima, H Hochegger, A Saberi, T Fukushima, K Kikuchi, M Yoshimura, BJ Orelli, DK Bishop, S Hirano, M Ohzeki, M Ishiai, K Yamamoto, M Takata, H Arakawa, JM Buerstedde, M Yamazoe, T Kawamoto, K Araki, JA Takahashi, N Hashimoto, S Takeda, E Sonoda K Nojima, H Hochegger, A Saberi, T Fukushima, K Kikuchi, M Yoshimura, BJ Orelli, DK Bishop, S Hirano, M Ohzeki, M Ishiai, K Yamamoto, M Takata, H Arakawa, JM Buerstedde, M Yamazoe, T Kawamoto, K Araki, JA Takahashi, N Hashimoto, S Takeda, E Sonoda Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells CANCER RESEARCH, 65, 24, 11704-11711 CANCER RESEARCH, 65, 24, 11704-11711 CANCER RESEARCH, 65, 24, 11704-11711 2005/12 Refereed English Research paper(scientific journal) Disclose to all
N Matsushita, H Kitao, M Ishiai, N Nagashima, S Hirano, K Okawa, T Ohta, DS Yu, PJ McHugh, ID Hickson, AR Venkitaraman, H Kurumizaka, M Takata N Matsushita, H Kitao, M Ishiai, N Nagashima, S Hirano, K Okawa, T Ohta, DS Yu, PJ McHugh, ID Hickson, AR Venkitaraman, H Kurumizaka, M Takata N Matsushita, H Kitao, M Ishiai, N Nagashima, S Hirano, K Okawa, T Ohta, DS Yu, PJ McHugh, ID Hickson, AR Venkitaraman, H Kurumizaka, M Takata A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair MOLECULAR CELL, 19, 6, 841-847 MOLECULAR CELL, 19, 6, 841-847 MOLECULAR CELL, 19, 6, 841-847 2005/09 Refereed English Research paper(scientific journal) Disclose to all
N Matsushita, Y Takami, M Kimura, S Tachiiri, M Ishiai, T Nakayama, M Takata N Matsushita, Y Takami, M Kimura, S Tachiiri, M Ishiai, T Nakayama, M Takata N Matsushita, Y Takami, M Kimura, S Tachiiri, M Ishiai, T Nakayama, M Takata Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells GENES TO CELLS, 10, 4, 321-332 GENES TO CELLS, 10, 4, 321-332 GENES TO CELLS, 10, 4, 321-332 2005/04 Refereed English Research paper(scientific journal) Disclose to all
S Hamimes, H Arakawa, AZ Stasiak, AM Kierzek, S Hirano, YG Yang, M Takata, A Stasiak, JM Buerstedde, E Van Dyck S Hamimes, H Arakawa, AZ Stasiak, AM Kierzek, S Hirano, YG Yang, M Takata, A Stasiak, JM Buerstedde, E Van Dyck S Hamimes, H Arakawa, AZ Stasiak, AM Kierzek, S Hirano, YG Yang, M Takata, A Stasiak, JM Buerstedde, E Van Dyck RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 10, 9225-9235 JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 10, 9225-9235 JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 10, 9225-9235 2005/03 Refereed English Research paper(scientific journal) Disclose to all
A Hatanaka, M Yamazoe, JE Sale, M Takata, K Yamamoto, H Kitao, E Sonoda, K Kikuchi, Y Yonetani, S Takeda A Hatanaka, M Yamazoe, JE Sale, M Takata, K Yamamoto, H Kitao, E Sonoda, K Kikuchi, Y Yonetani, S Takeda A Hatanaka, M Yamazoe, JE Sale, M Takata, K Yamamoto, H Kitao, E Sonoda, K Kikuchi, Y Yonetani, S Takeda Similar effects of BRCA2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination Similar effects of BRCA2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination Similar effects of BRCA2 truncation and Rad51 paralog deficiency on immunoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination MOLECULAR AND CELLULAR BIOLOGY, 25, 3, 1124-1134 MOLECULAR AND CELLULAR BIOLOGY, 25, 3, 1124-1134 MOLECULAR AND CELLULAR BIOLOGY, 25, 3, 1124-1134 2005/02 Refereed English Research paper(scientific journal) Disclose to all
K Yamamoto, S Hirano, M Ishiai, K Morishima, H Kitao, K Namikoshi, M Kimura, N Matsushita, H Arakawa, JM Buerstedde, K Komatsu, LH Thompson, M Takata K Yamamoto, S Hirano, M Ishiai, K Morishima, H Kitao, K Namikoshi, M Kimura, N Matsushita, H Arakawa, JM Buerstedde, K Komatsu, LH Thompson, M Takata K Yamamoto, S Hirano, M Ishiai, K Morishima, H Kitao, K Namikoshi, M Kimura, N Matsushita, H Arakawa, JM Buerstedde, K Komatsu, LH Thompson, M Takata Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 34-43 MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 34-43 MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 34-43 2005/01 Refereed English Research paper(scientific journal) Disclose to all
S Hirano, K Yamamoto, M Ishiai, M Yamazoe, M Seki, N Matsushita, M Ohzeki, YM Yamashita, H Arakawa, JM Buerstedde, T Enomoto, S Takeda, LH Thompson, M Takata S Hirano, K Yamamoto, M Ishiai, M Yamazoe, M Seki, N Matsushita, M Ohzeki, YM Yamashita, H Arakawa, JM Buerstedde, T Enomoto, S Takeda, LH Thompson, M Takata S Hirano, K Yamamoto, M Ishiai, M Yamazoe, M Seki, N Matsushita, M Ohzeki, YM Yamashita, H Arakawa, JM Buerstedde, T Enomoto, S Takeda, LH Thompson, M Takata Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM EMBO JOURNAL, 24, 2, 418-427 EMBO JOURNAL, 24, 2, 418-427 EMBO JOURNAL, 24, 2, 418-427 2005/01 Refereed English Research paper(scientific journal) Disclose to all
M Ishiai, M Kimura, K Namikoshi, M Yamazoe, K Yamamoto, H Arakawa, K Agematsu, N Matsushita, S Takeda, JM Buerstedde, M Takata M Ishiai, M Kimura, K Namikoshi, M Yamazoe, K Yamamoto, H Arakawa, K Agematsu, N Matsushita, S Takeda, JM Buerstedde, M Takata M Ishiai, M Kimura, K Namikoshi, M Yamazoe, K Yamamoto, H Arakawa, K Agematsu, N Matsushita, S Takeda, JM Buerstedde, M Takata DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation MOLECULAR AND CELLULAR BIOLOGY, 24, 24, 10733-10741 MOLECULAR AND CELLULAR BIOLOGY, 24, 24, 10733-10741 MOLECULAR AND CELLULAR BIOLOGY, 24, 24, 10733-10741 2004/12 Refereed English Research paper(scientific journal) Disclose to all
MS Sasaki, M Takata, E Sonoda, A Tachibana, S Takeda MS Sasaki, M Takata, E Sonoda, A Tachibana, S Takeda MS Sasaki, M Takata, E Sonoda, A Tachibana, S Takeda Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks CYTOGENETIC AND GENOME RESEARCH, 104, 1-4, 28-34 CYTOGENETIC AND GENOME RESEARCH, 104, 1-4, 28-34 CYTOGENETIC AND GENOME RESEARCH, 104, 1-4, 28-34 2004 Refereed English Research paper(scientific journal) Disclose to all
K Yamamoto, M Ishiai, N Matsushita, H Arakawa, JE Lamerdin, JM Buerstedde, M Tanimoto, M Harada, LH Thompson, M Takata K Yamamoto, M Ishiai, N Matsushita, H Arakawa, JE Lamerdin, JM Buerstedde, M Tanimoto, M Harada, LH Thompson, M Takata K Yamamoto, M Ishiai, N Matsushita, H Arakawa, JE Lamerdin, JM Buerstedde, M Tanimoto, M Harada, LH Thompson, M Takata Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells MOLECULAR AND CELLULAR BIOLOGY, 23, 15, 5421-5430 MOLECULAR AND CELLULAR BIOLOGY, 23, 15, 5421-5430 MOLECULAR AND CELLULAR BIOLOGY, 23, 15, 5421-5430 2003/08 Refereed English Research paper(scientific journal) Disclose to all
M Hashimoto, S Rao, O Tokuno, KI Yamamoto, M Takata, S Takeda, H Utsumi M Hashimoto, S Rao, O Tokuno, KI Yamamoto, M Takata, S Takeda, H Utsumi M Hashimoto, S Rao, O Tokuno, KI Yamamoto, M Takata, S Takeda, H Utsumi DNA-PK: the major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway DNA-PK: the major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway DNA-PK: the major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway JOURNAL OF RADIATION RESEARCH, 44, 2, 151-159 JOURNAL OF RADIATION RESEARCH, 44, 2, 151-159 JOURNAL OF RADIATION RESEARCH, 44, 2, 151-159 2003/06 Refereed English Research paper(scientific journal) Disclose to all
E Sonoda, T Okada, GY Zhaol, S Tateishi, K Araki, M Yarnaizumi, T Yagi, NS Verkaik, DC van Gent, M Takata, S Takeda E Sonoda, T Okada, GY Zhaol, S Tateishi, K Araki, M Yarnaizumi, T Yagi, NS Verkaik, DC van Gent, M Takata, S Takeda E Sonoda, T Okada, GY Zhaol, S Tateishi, K Araki, M Yarnaizumi, T Yagi, NS Verkaik, DC van Gent, M Takata, S Takeda Multiple roles of Rev3, the catalytic subunit of pole in maintaining genome stability in vertebrates Multiple roles of Rev3, the catalytic subunit of pole in maintaining genome stability in vertebrates Multiple roles of Rev3, the catalytic subunit of pole in maintaining genome stability in vertebrates EMBO JOURNAL, 22, 12, 3188-3197 EMBO JOURNAL, 22, 12, 3188-3197 EMBO JOURNAL, 22, 12, 3188-3197 2003/06 Refereed English Research paper(scientific journal) Disclose to all
Takashi Okada, Eiichiro Sonoda, Yukiko M. Yamashita, Shogo Koyoshi, Satoshi Tateishi, Masaru Yamaizumi, Minoru Takata, Osamu Ogawa, Shunichi Takeda Takashi Okada, Eiichiro Sonoda, Yukiko M. Yamashita, Shogo Koyoshi, Satoshi Tateishi, Masaru Yamaizumi, Minoru Takata, Osamu Ogawa, Shunichi Takeda Takashi Okada, Eiichiro Sonoda, Yukiko M. Yamashita, Shogo Koyoshi, Satoshi Tateishi, Masaru Yamaizumi, Minoru Takata, Osamu Ogawa, Shunichi Takeda Involvement of vertebrate Polκ in Rad18-independent postreplication repair of UV damage Involvement of vertebrate Polκ in Rad18-independent postreplication repair of UV damage Involvement of vertebrate Polκ in Rad18-independent postreplication repair of UV damage Journal of Biological Chemistry, 277, 50, 48690-48695 Journal of Biological Chemistry, 277, 50, 48690-48695 Journal of Biological Chemistry, 277, 50, 48690-48695 2002/12/13 Refereed English Research paper(scientific journal) Disclose to all
H Tauchi, J Kobayashi, K Morishima, DC van Gent, T Shiraishi, NS Verkaik, D vanHeems, E Ito, A Nakamura, E Sonodo, M Takata, S Takeda, S Matsuura, K Komatsu H Tauchi, J Kobayashi, K Morishima, DC van Gent, T Shiraishi, NS Verkaik, D vanHeems, E Ito, A Nakamura, E Sonodo, M Takata, S Takeda, S Matsuura, K Komatsu H Tauchi, J Kobayashi, K Morishima, DC van Gent, T Shiraishi, NS Verkaik, D vanHeems, E Ito, A Nakamura, E Sonodo, M Takata, S Takeda, S Matsuura, K Komatsu Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells NATURE, 420, 6911, 93-98 NATURE, 420, 6911, 93-98 NATURE, 420, 6911, 93-98 2002/11 Refereed English Research paper(scientific journal) Disclose to all
M Takata, S Tachiiri, A Fujimori, LH Thompson, Y Miki, M Hiraoka, S Takeda, M Yamazaoe M Takata, S Tachiiri, A Fujimori, LH Thompson, Y Miki, M Hiraoka, S Takeda, M Yamazaoe M Takata, S Tachiiri, A Fujimori, LH Thompson, Y Miki, M Hiraoka, S Takeda, M Yamazaoe Conserved domains in the chicken homologue of BRCA2 Conserved domains in the chicken homologue of BRCA2 Conserved domains in the chicken homologue of BRCA2 ONCOGENE, 21, 7, 1130-1134 ONCOGENE, 21, 7, 1130-1134 ONCOGENE, 21, 7, 1130-1134 2002/02 Refereed English Research paper(scientific journal) Disclose to all
C. Wei, R. Skopp, M. Takata, S. Takeda, C.M. Price C. Wei, R. Skopp, M. Takata, S. Takeda, C.M. Price C. Wei, R. Skopp, M. Takata, S. Takeda, C.M. Price Effects of double-strand break repair proteins on vertebrate telomere structure Effects of double-strand break repair proteins on vertebrate telomere structure Effects of double-strand break repair proteins on vertebrate telomere structure Nucleic Acids Research, 30, 13, 2862-2870 Nucleic Acids Research, 30, 13, 2862-2870 Nucleic Acids Research, 30, 13, 2862-2870 2002 Refereed English Disclose to all
Toru Fukushima, Minoru Takata, Ciaran Morrison, Ryoko Araki, Akira Fujimori, Masumi Abe, Kouichi Tatsumi, Maria Jasin, Pawan Kumar Dhar, Eiichiro Sonoda, Tsutomu Chiba, Shunichi Takeda Toru Fukushima, Minoru Takata, Ciaran Morrison, Ryoko Araki, Akira Fujimori, Masumi Abe, Kouichi Tatsumi, Maria Jasin, Pawan Kumar Dhar, Eiichiro Sonoda, Tsutomu Chiba, Shunichi Takeda Toru Fukushima, Minoru Takata, Ciaran Morrison, Ryoko Araki, Akira Fujimori, Masumi Abe, Kouichi Tatsumi, Maria Jasin, Pawan Kumar Dhar, Eiichiro Sonoda, Tsutomu Chiba, Shunichi Takeda Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S-G<inf>2</inf> Phase DNA Double-strand Break Repair Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S-G<inf>2</inf> Phase DNA Double-strand Break Repair Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S-G<inf>2</inf> Phase DNA Double-strand Break Repair Journal of Biological Chemistry, 276, 48, 44413-44418 Journal of Biological Chemistry, 276, 48, 44413-44418 Journal of Biological Chemistry, 276, 48, 44413-44418 2001/11/30 Refereed English Research paper(scientific journal) Disclose to all
A Fujimori, S Tachiiri, E Sonoda, LH Thompson, PK Dhar, M Hiraoka, S Takeda, Y Zhang, M Reth, M Takata A Fujimori, S Tachiiri, E Sonoda, LH Thompson, PK Dhar, M Hiraoka, S Takeda, Y Zhang, M Reth, M Takata A Fujimori, S Tachiiri, E Sonoda, LH Thompson, PK Dhar, M Hiraoka, S Takeda, Y Zhang, M Reth, M Takata Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells EMBO JOURNAL, 20, 19, 5513-5520 EMBO JOURNAL, 20, 19, 5513-5520 EMBO JOURNAL, 20, 19, 5513-5520 2001/10 Refereed English Research paper(scientific journal) Disclose to all
Julian E. Sale, Daniella M. Calandrini, Minoru Takata, Shunichi Takeda, Michael S. Neuberger Julian E. Sale, Daniella M. Calandrini, Minoru Takata, Shunichi Takeda, Michael S. Neuberger Julian E. Sale, Daniella M. Calandrini, Minoru Takata, Shunichi Takeda, Michael S. Neuberger Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation [4] Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation [4] Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation [4] Nature, 412, 6850, 921-926 Nature, 412, 6850, 921-926 Nature, 412, 6850, 921-926 2001/08/30 Refereed English Research paper(scientific journal) Disclose to all
H Utsumi, K Tano, M Takata, S Takeda, MM Elkind H Utsumi, K Tano, M Takata, S Takeda, MM Elkind H Utsumi, K Tano, M Takata, S Takeda, MM Elkind Requirement for repair of DNA double-strand breaks by homologous recombination in split-dose recovery Requirement for repair of DNA double-strand breaks by homologous recombination in split-dose recovery Requirement for repair of DNA double-strand breaks by homologous recombination in split-dose recovery RADIATION RESEARCH, 155, 5, 680-686 RADIATION RESEARCH, 155, 5, 680-686 RADIATION RESEARCH, 155, 5, 680-686 2001/05 Refereed English Research paper(scientific journal) Disclose to all
HC Wang, ZC Zeng, TA Bui, E Sonoda, M Takata, S Takeda, G Iliakis HC Wang, ZC Zeng, TA Bui, E Sonoda, M Takata, S Takeda, G Iliakis HC Wang, ZC Zeng, TA Bui, E Sonoda, M Takata, S Takeda, G Iliakis Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group ONCOGENE, 20, 18, 2212-2224 ONCOGENE, 20, 18, 2212-2224 ONCOGENE, 20, 18, 2212-2224 2001/04 Refereed English Disclose to all
M Takata, MS Sasaki, S Tachiiri, T Fukushima, E Sonoda, D Schild, LH Thompson, S Takeda M Takata, MS Sasaki, S Tachiiri, T Fukushima, E Sonoda, D Schild, LH Thompson, S Takeda M Takata, MS Sasaki, S Tachiiri, T Fukushima, E Sonoda, D Schild, LH Thompson, S Takeda Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs MOLECULAR AND CELLULAR BIOLOGY, 21, 8, 2858-2866 MOLECULAR AND CELLULAR BIOLOGY, 21, 8, 2858-2866 MOLECULAR AND CELLULAR BIOLOGY, 21, 8, 2858-2866 2001/04 Refereed English Research paper(scientific journal) Disclose to all
E. Sonoda, M. Takata, Y.M. Yamashita, S. Takeda E. Sonoda, M. Takata, Y.M. Yamashita, S. Takeda E. Sonoda, M. Takata, Y.M. Yamashita, S. Takeda Homologous DNA recombination is essential for the proliferation of vertebrate cells Homologous DNA recombination is essential for the proliferation of vertebrate cells Homologous DNA recombination is essential for the proliferation of vertebrate cells Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 46, 8 Suppl, 1046-1054 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 46, 8 Suppl, 1046-1054 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 46, 8 Suppl, 1046-1054 2001 Refereed English Disclose to all
E Sonoda, C Morrison, YM Yamashita, M Takata, S Takeda E Sonoda, C Morrison, YM Yamashita, M Takata, S Takeda E Sonoda, C Morrison, YM Yamashita, M Takata, S Takeda Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40 Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40 Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 356, 1405, 111-117 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 356, 1405, 111-117 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 356, 1405, 111-117 2001/01 Refereed English Research paper(scientific journal) Disclose to all
M Takata, MS Sasaki, E Sonoda, T Fukushima, C Morrison, JS Albala, SMA Swagemakers, R Kanaar, LH Thompson, S Takeda M Takata, MS Sasaki, E Sonoda, T Fukushima, C Morrison, JS Albala, SMA Swagemakers, R Kanaar, LH Thompson, S Takeda M Takata, MS Sasaki, E Sonoda, T Fukushima, C Morrison, JS Albala, SMA Swagemakers, R Kanaar, LH Thompson, S Takeda The Rad51 paralog Rad51B promotes homologous recombinational repair The Rad51 paralog Rad51B promotes homologous recombinational repair The Rad51 paralog Rad51B promotes homologous recombinational repair MOLECULAR AND CELLULAR BIOLOGY, 20, 17, 6476-6482 MOLECULAR AND CELLULAR BIOLOGY, 20, 17, 6476-6482 MOLECULAR AND CELLULAR BIOLOGY, 20, 17, 6476-6482 2000/09 Refereed English Research paper(scientific journal) Disclose to all
T Kurosaki, A Maeda, M Ishiai, A Hashimoto, K Inabe, M Takata T Kurosaki, A Maeda, M Ishiai, A Hashimoto, K Inabe, M Takata T Kurosaki, A Maeda, M Ishiai, A Hashimoto, K Inabe, M Takata Regulation of the phospholipase C-gamma 2 pathway in B cells Regulation of the phospholipase C-gamma 2 pathway in B cells Regulation of the phospholipase C-gamma 2 pathway in B cells IMMUNOLOGICAL REVIEWS, 176, 19-29 IMMUNOLOGICAL REVIEWS, 176, 19-29 IMMUNOLOGICAL REVIEWS, 176, 19-29 2000/08 Refereed English Disclose to all
Y Yamaguchi-Iwai, E Sonoda, MS Sasaki, C Morrison, T Haraguchi, Y Hiraoka, YM Yamashita, T Yagi, M Takata, C Price, N Kakazu, S Takeda Y Yamaguchi-Iwai, E Sonoda, MS Sasaki, C Morrison, T Haraguchi, Y Hiraoka, YM Yamashita, T Yagi, M Takata, C Price, N Kakazu, S Takeda Y Yamaguchi-Iwai, E Sonoda, MS Sasaki, C Morrison, T Haraguchi, Y Hiraoka, YM Yamashita, T Yagi, M Takata, C Price, N Kakazu, S Takeda Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells EMBO JOURNAL, 18, 23, 6619-6629 EMBO JOURNAL, 18, 23, 6619-6629 EMBO JOURNAL, 18, 23, 6619-6629 1999/12 Refereed English Research paper(scientific journal) Disclose to all
C Morrison, A Shinohara, E Sonoda, Y Yamaguchi-Iwai, M Takata, RR Weichselbaum, S Takeda C Morrison, A Shinohara, E Sonoda, Y Yamaguchi-Iwai, M Takata, RR Weichselbaum, S Takeda C Morrison, A Shinohara, E Sonoda, Y Yamaguchi-Iwai, M Takata, RR Weichselbaum, S Takeda The essential functions of human Rad51 are independent of ATP hydrolysis The essential functions of human Rad51 are independent of ATP hydrolysis The essential functions of human Rad51 are independent of ATP hydrolysis MOLECULAR AND CELLULAR BIOLOGY, 19, 10, 6891-6897 MOLECULAR AND CELLULAR BIOLOGY, 19, 10, 6891-6897 MOLECULAR AND CELLULAR BIOLOGY, 19, 10, 6891-6897 1999/10 Refereed English Research paper(scientific journal) Disclose to all
E Sonoda, MS Sasaki, C Morrison, Y Yamaguchi-Iwai, M Takata, S Takeda E Sonoda, MS Sasaki, C Morrison, Y Yamaguchi-Iwai, M Takata, S Takeda E Sonoda, MS Sasaki, C Morrison, Y Yamaguchi-Iwai, M Takata, S Takeda Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells MOLECULAR AND CELLULAR BIOLOGY, 19, 7, 5166-5169 MOLECULAR AND CELLULAR BIOLOGY, 19, 7, 5166-5169 MOLECULAR AND CELLULAR BIOLOGY, 19, 7, 5166-5169 1999/07 Refereed English Research paper(scientific journal) Disclose to all
Y Yamaguchi-Iwai, E Sonoda, JM Buerstedde, O Bezzubova, C Morrison, M Takata, A Shinohara, S Takeda Y Yamaguchi-Iwai, E Sonoda, JM Buerstedde, O Bezzubova, C Morrison, M Takata, A Shinohara, S Takeda Y Yamaguchi-Iwai, E Sonoda, JM Buerstedde, O Bezzubova, C Morrison, M Takata, A Shinohara, S Takeda Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52 Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52 Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52 MOLECULAR AND CELLULAR BIOLOGY, 18, 11, 6430-6435 MOLECULAR AND CELLULAR BIOLOGY, 18, 11, 6430-6435 MOLECULAR AND CELLULAR BIOLOGY, 18, 11, 6430-6435 1998/11 Refereed English Research paper(scientific journal) Disclose to all
M Takata, MS Sasaki, E Sonoda, C Morrison, M Hashimoto, H Utsumi, Y Yamaguchi-Iwai, A Shinohara, S Takeda M Takata, MS Sasaki, E Sonoda, C Morrison, M Hashimoto, H Utsumi, Y Yamaguchi-Iwai, A Shinohara, S Takeda M Takata, MS Sasaki, E Sonoda, C Morrison, M Hashimoto, H Utsumi, Y Yamaguchi-Iwai, A Shinohara, S Takeda Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells EMBO JOURNAL, 17, 18, 5497-5508 EMBO JOURNAL, 17, 18, 5497-5508 EMBO JOURNAL, 17, 18, 5497-5508 1998/09 Refereed English Research paper(scientific journal) Disclose to all
S Takeda, E Sonoda, M Takata, C Morrison, S Tachiiri, Y Yamaguchi-Iwai S Takeda, E Sonoda, M Takata, C Morrison, S Tachiiri, Y Yamaguchi-Iwai S Takeda, E Sonoda, M Takata, C Morrison, S Tachiiri, Y Yamaguchi-Iwai Recombinational repair is essential for the maintenance of chromosomal integrity in cycling vertebrate cells. Recombinational repair is essential for the maintenance of chromosomal integrity in cycling vertebrate cells. Recombinational repair is essential for the maintenance of chromosomal integrity in cycling vertebrate cells. EXPERIMENTAL HEMATOLOGY, 26, 8, 738-738 EXPERIMENTAL HEMATOLOGY, 26, 8, 738-738 EXPERIMENTAL HEMATOLOGY, 26, 8, 738-738 1998/08 Refereed English Disclose to all
E Sonoda, MS Sasaki, JM Buerstedde, O Bezzubova, A Shinohara, H Ogawa, M Takata, Y Yamaguchi-Iwai, S Takeda E Sonoda, MS Sasaki, JM Buerstedde, O Bezzubova, A Shinohara, H Ogawa, M Takata, Y Yamaguchi-Iwai, S Takeda E Sonoda, MS Sasaki, JM Buerstedde, O Bezzubova, A Shinohara, H Ogawa, M Takata, Y Yamaguchi-Iwai, S Takeda Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death EMBO JOURNAL, 17, 2, 598-608 EMBO JOURNAL, 17, 2, 598-608 EMBO JOURNAL, 17, 2, 598-608 1998/01 Refereed English Research paper(scientific journal) Disclose to all
Minoru Takata, Kiyoshi Takahashi, Ryou Souda, Yasuo Nanba, Kazuo Ogurusu, Arihiko Kanehiro, Hisashi Sugano, Yasushi Tanimoto, Kouichi Yamagata, Noriko Kawada, Ikuro Kimura Minoru Takata, Kiyoshi Takahashi, Ryou Souda, Yasuo Nanba, Kazuo Ogurusu, Arihiko Kanehiro, Hisashi Sugano, Yasushi Tanimoto, Kouichi Yamagata, Noriko Kawada, Ikuro Kimura Minoru Takata, Kiyoshi Takahashi, Ryou Souda, Yasuo Nanba, Kazuo Ogurusu, Arihiko Kanehiro, Hisashi Sugano, Yasushi Tanimoto, Kouichi Yamagata, Noriko Kawada, Ikuro Kimura A case of dyskeratosis congenita with highly elevated serum IgE A case of dyskeratosis congenita with highly elevated serum IgE A case of dyskeratosis congenita with highly elevated serum IgE Japanese Journal of Clinical Immunology, 15, 2, 190-195 Japanese Journal of Clinical Immunology, 15, 2, 190-195 Japanese Journal of Clinical Immunology, 15, 2, 190-195 1992 Refereed English Research paper(scientific journal) Disclose to all

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Donovan FX, Solanki A, Mori M, Chavan N, George M, C SK, Okuno Y, Muramastsu H, Yoshida K, Shimamoto A, Takaori-Kondo A, Yabe H, Ogawa S, Kojima S, Yabe M, Ramanagoudr-Bhojappa R, Smogorzewska A, Mohan S, Rajendran A, Auerbach AD, Takata M, Chandrasekharappa SC, Vundinti BR Donovan FX, Solanki A, Mori M, Chavan N, George M, C SK, Okuno Y, Muramastsu H, Yoshida K, Shimamoto A, Takaori-Kondo A, Yabe H, Ogawa S, Kojima S, Yabe M, Ramanagoudr-Bhojappa R, Smogorzewska A, Mohan S, Rajendran A, Auerbach AD, Takata M, Chandrasekharappa SC, Vundinti BR Donovan FX, Solanki A, Mori M, Chavan N, George M, C SK, Okuno Y, Muramastsu H, Yoshida K, Shimamoto A, Takaori-Kondo A, Yabe H, Ogawa S, Kojima S, Yabe M, Ramanagoudr-Bhojappa R, Smogorzewska A, Mohan S, Rajendran A, Auerbach AD, Takata M, Chandrasekharappa SC, Vundinti BR A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India. A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India. A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia cases in India. Human mutation Human mutation Human mutation 2019/09 Refereed Disclose to all
Makimoto G, Ohashi K, Tomida S, Nishii K, Matsubara T, Kayatani H, Higo H, Ninomiya K, Sato A, Watanabe H, Kano H, Ninomiya T, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Toyooka S, Takata M, Maeda Y, Kiura K Makimoto G, Ohashi K, Tomida S, Nishii K, Matsubara T, Kayatani H, Higo H, Ninomiya K, Sato A, Watanabe H, Kano H, Ninomiya T, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Toyooka S, Takata M, Maeda Y, Kiura K Makimoto G, Ohashi K, Tomida S, Nishii K, Matsubara T, Kayatani H, Higo H, Ninomiya K, Sato A, Watanabe H, Kano H, Ninomiya T, Kubo T, Rai K, Ichihara E, Hotta K, Tabata M, Toyooka S, Takata M, Maeda Y, Kiura K Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden. Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden. Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019/07 Refereed Disclose to all
Okamoto Y, Hejna J, Takata M Okamoto Y, Hejna J, Takata M Okamoto Y, Hejna J, Takata M Regulation of R-loops and genome instability in Fanconi anemia. Regulation of R-loops and genome instability in Fanconi anemia. Regulation of R-loops and genome instability in Fanconi anemia. Journal of biochemistry, 165, 6, 465-470 Journal of biochemistry, 165, 6, 465-470 Journal of biochemistry, 165, 6, 465-470 2019/06 Refereed Disclose to all
Ninomiya K, Hata T, Yoshioka H, Ohashi K, Bessho A, Hosokawa S, Ishikawa N, Yamasaki M, Shibayama T, Aoe K, Kozuki T, Harita S, Ueda Y, Murakami T, Fujimoto N, Yanai H, Toyooka S, Takata M, Hotta K, Kiura K, HER2-CS Network Ninomiya K, Hata T, Yoshioka H, Ohashi K, Bessho A, Hosokawa S, Ishikawa N, Yamasaki M, Shibayama T, Aoe K, Kozuki T, Harita S, Ueda Y, Murakami T, Fujimoto N, Yanai H, Toyooka S, Takata M, Hotta K, Kiura K, HER2-CS Network Ninomiya K, Hata T, Yoshioka H, Ohashi K, Bessho A, Hosokawa S, Ishikawa N, Yamasaki M, Shibayama T, Aoe K, Kozuki T, Harita S, Ueda Y, Murakami T, Fujimoto N, Yanai H, Toyooka S, Takata M, Hotta K, Kiura K, HER2-CS Network A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY). A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY). A Prospective Cohort Study to Define the Clinical Features and Outcome of Lung Cancers Harboring HER2 Aberration in Japan (HER2-CS STUDY). Chest Chest Chest 2019/05 Refereed Disclose to all
勝木 陽子, 高田 穣 勝木 陽子, 高田 穣 複製ストレス応答によるゲノム安定化メカニズム 複製ストレス応答によるゲノム安定化メカニズム 遺伝子医学, 30 遺伝子医学, 30 , 30 2019 Japanese Article, review, commentary, editorial, etc.(scientific journal) Disclose to all
Okamoto Y, Abe M, Itaya A, Tomida J, Ishiai M, Takaori-Kondo A, Taoka M, Isobe T, Takata M Okamoto Y, Abe M, Itaya A, Tomida J, Ishiai M, Takaori-Kondo A, Taoka M, Isobe T, Takata M Okamoto Y, Abe M, Itaya A, Tomida J, Ishiai M, Takaori-Kondo A, Taoka M, Isobe T, Takata M FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress. FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress. FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress. The FEBS journal, 286, 1, 139-150 The FEBS journal, 286, 1, 139-150 The FEBS journal, 286, 1, 139-150 2019/01 Refereed Disclose to all
Mori M, Yabe H, Yabe M, Takata M Mori M, Yabe H, Yabe M, Takata M Mori M, Yabe H, Yabe M, Takata M [Genetic analysis of Japanese patients with Fanconi anemia: novel findings]. [Genetic analysis of Japanese patients with Fanconi anemia: novel findings]. [Genetic analysis of Japanese patients with Fanconi anemia: novel findings]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 60, 6, 691-701 [Rinsho ketsueki] The Japanese journal of clinical hematology, 60, 6, 691-701 [Rinsho ketsueki] The Japanese journal of clinical hematology, 60, 6, 691-701 2019 Refereed Disclose to all
森 美奈子, 平 明日香, 吉田 健一, 村松 秀城, 奥野 友介, 庵前 美智子, 田村 和朗, 安田 純, 大隅 朋生, 野口 靖, 川端 浩, 高折 晃史, 小島 勢二, 小川 誠司, 矢部 普正, 矢部 みはる, 高田 穰 森 美奈子, 平 明日香, 吉田 健一, 村松 秀城, 奥野 友介, 庵前 美智子, 田村 和朗, 安田 純, 大隅 朋生, 野口 靖, 川端 浩, 高折 晃史, 小島 勢二, 小川 誠司, 矢部 普正, 矢部 みはる, 高田 穰 森 美奈子, 平 明日香, 吉田 健一, 村松 秀城, 奥野 友介, 庵前 美智子, 田村 和朗, 安田 純, 大隅 朋生, 野口 靖, 川端 浩, 高折 晃史, 小島 勢二, 小川 誠司, 矢部 普正, 矢部 みはる, 高田 穰 日本人ファンコニ貧血患者117人の原因遺伝子と臨床症状の解析(Evaluation of pathogenic variants and clinical characteristics in Japanese Fanconi anemia patients) 日本人ファンコニ貧血患者117人の原因遺伝子と臨床症状の解析(Evaluation of pathogenic variants and clinical characteristics in Japanese Fanconi anemia patients) 日本人ファンコニ貧血患者117人の原因遺伝子と臨床症状の解析(Evaluation of pathogenic variants and clinical characteristics in Japanese Fanconi anemia patients) 臨床血液, 59, 9, 1625-1625 臨床血液, 59, 9, 1625-1625 臨床血液, 59, 9, 1625-1625 2018/09 English Disclose to all
藤池春奈, Mahmoud SHOULKAMY, Amir SALEM, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 井出博, 田野恵三 藤池春奈, Mahmoud SHOULKAMY, Amir SALEM, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 井出博, 田野恵三 DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝⼦産物の関与 DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝⼦産物の関与 第40回日本分子生物学会年会 第40回日本分子生物学会年会 2017/12 Refereed Japanese Research paper, summary (national conference and other science council) Disclose to all
Kadoaki Ohashi, Katsuyuki Hotta, Taizo Hirata, Keisuke Aoe, Toshiyuki Kozuki, Kiichiro Ninomiya, Hiroe Kayatani, Hiroyuki Yanai, Shinichi Toyooka, Shiro Hinotsu, Minoru Takata, Katsuyuki Kiura Kadoaki Ohashi, Katsuyuki Hotta, Taizo Hirata, Keisuke Aoe, Toshiyuki Kozuki, Kiichiro Ninomiya, Hiroe Kayatani, Hiroyuki Yanai, Shinichi Toyooka, Shiro Hinotsu, Minoru Takata, Katsuyuki Kiura Kadoaki Ohashi, Katsuyuki Hotta, Taizo Hirata, Keisuke Aoe, Toshiyuki Kozuki, Kiichiro Ninomiya, Hiroe Kayatani, Hiroyuki Yanai, Shinichi Toyooka, Shiro Hinotsu, Minoru Takata, Katsuyuki Kiura Trastuzumab Emtansine in HER2+Recurrent Metastatic Non-Small-Cell Lung Cancer: Study Protocol Trastuzumab Emtansine in HER2+Recurrent Metastatic Non-Small-Cell Lung Cancer: Study Protocol Trastuzumab Emtansine in HER2+Recurrent Metastatic Non-Small-Cell Lung Cancer: Study Protocol CLINICAL LUNG CANCER, 18, 1, 92-95 CLINICAL LUNG CANCER, 18, 1, 92-95 CLINICAL LUNG CANCER, 18, 1, 92-95 2017/01 Refereed English Disclose to all
角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 井出博, 武田俊一, 増永慎一郎, 田野恵三 角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 井出博, 武田俊一, 増永慎一郎, 田野恵三 低グルコースにおいて致死作用をもつメトフォルミンとフェンフォルミンの作用機序の解析 低グルコースにおいて致死作用をもつメトフォルミンとフェンフォルミンの作用機序の解析 日本環境変異原学会第45回大会 日本環境変異原学会第45回大会 2016/11 Refereed Japanese Research paper, summary (national conference and other science council) Disclose to all
角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 井出博, 武田俊一, 増永慎一郎, 田野恵三 角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 井出博, 武田俊一, 増永慎一郎, 田野恵三 DT40ノックアウト細胞を用いたBiguanide系薬剤Metforminによるグルコース枯渇下細胞致死作用の解析 DT40ノックアウト細胞を用いたBiguanide系薬剤Metforminによるグルコース枯渇下細胞致死作用の解析 第39回日本分子生物学会年会 第39回日本分子生物学会年会 2016/11 Refereed Japanese Research paper, summary (national conference and other science council) Disclose to all
角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 田野恵三 角田圭, 森脇隆仁, 藤池春奈, 津田雅貴, 笹沼博之, 高田穣, 武田俊一, 増永慎一郎, 田野恵三 DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死性作用を持つ Biguanide薬剤の作用機序の解析 DT40ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死性作用を持つ Biguanide薬剤の作用機序の解析 日本放射線影響学会第59回大会 日本放射線影響学会第59回大会 2016/10 Refereed Japanese Research paper, summary (national conference and other science council) Disclose to all
Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Yaling Huang, Justin W. C. Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li Modularized Functions of the Fanconi Anemia Core Complex (vol 7, pg 1849, 2014) Modularized Functions of the Fanconi Anemia Core Complex (vol 7, pg 1849, 2014) Modularized Functions of the Fanconi Anemia Core Complex (vol 7, pg 1849, 2014) CELL REPORTS, 14, 11, 2761-2763 CELL REPORTS, 14, 11, 2761-2763 CELL REPORTS, 14, 11, 2761-2763 2016/03 English Other Disclose to all
西村浩平, 夏目豊彰, 石合正道, 深川竜郎, 高田穣, 鐘巻将人 西村浩平, 夏目豊彰, 石合正道, 深川竜郎, 高田穣, 鐘巻将人 西村浩平, 夏目豊彰, 石合正道, 深川竜郎, 高田穣, 鐘巻将人 Mcm8‐9複合体はRad51依存的鎖潜り込み反応後のDNA伸長反応に関わる Mcm8‐9複合体はRad51依存的鎖潜り込み反応後のDNA伸長反応に関わる Mcm8‐9複合体はRad51依存的鎖潜り込み反応後のDNA伸長反応に関わる 日本分子生物学会年会プログラム・要旨集(Web), 36th, 1PW8-5 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 36th, 1PW8-5 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 36th, 1PW8-5 (WEB ONLY) 2013 Japanese Disclose to all
穀田哲也, 勅使河原愛, 長谷川直己, 飯島健太, 高田穣, 小松賢志, 田内広 穀田哲也, 勅使河原愛, 長谷川直己, 飯島健太, 高田穣, 小松賢志, 田内広 “DNA 二重鎖切断修復における 相同組換え修復の細胞周期依存性の解析” “DNA 二重鎖切断修復における 相同組換え修復の細胞周期依存性の解析” 第35 回日本分子生物学会年会 2012 年12 月 第35 回日本分子生物学会年会 2012 年12 月 2012 Refereed Japanese Disclose to all
佐藤浩一, 石合正道, 高田穣, 胡桃坂仁志 佐藤浩一, 石合正道, 高田穣, 胡桃坂仁志 “FANCD2 のモノユピキチン化機構の解析” “FANCD2 のモノユピキチン化機構の解析” 第35 回日本分子生物学会年会 2012年12月 第35 回日本分子生物学会年会 2012年12月 2012 Refereed Japanese Disclose to all
石合正道, 佐藤浩一, 胡桃坂仁志, 高田穣 石合正道, 佐藤浩一, 胡桃坂仁志, 高田穣 “FANCD2 のヒストンシャペロン活性がDNA 修復機能に果たす役 割” “FANCD2 のヒストンシャペロン活性がDNA 修復機能に果たす役 割” 第35回日本分子生物学会年会 ポスターよりワークショップへ採択 2012年12月 第35回日本分子生物学会年会 ポスターよりワークショップへ採択 2012年12月 2012 Refereed Japanese Disclose to all
西村浩平, 石合正道, 堀川一樹, 深川竜郎, 高田穣, 滝澤温彦, 鐘巻将人 西村浩平, 石合正道, 堀川一樹, 深川竜郎, 高田穣, 滝澤温彦, 鐘巻将人 “Mcm8 とMcm9 は複合体を形成し、 DNA 二本鎖架橋修復時に引き起こされる相同組換え修復において働く” “Mcm8 とMcm9 は複合体を形成し、 DNA 二本鎖架橋修復時に引き起こされる相同組換え修復において働く” 第35 回日本分子生物学会年会 2012 年12 月 ポスターよりワークショップへ採択 第35 回日本分子生物学会年会 2012 年12 月 ポスターよりワークショップへ採択 2012 Refereed Japanese Disclose to all
高田穣, 平明日香, 鈴木直也, 丹羽明, 中畑龍俊, 矢部普正, 斉藤潤, 松尾恵太郎, 矢部みはる 高田穣, 平明日香, 鈴木直也, 丹羽明, 中畑龍俊, 矢部普正, 斉藤潤, 松尾恵太郎, 矢部みはる “ファン コニ貧血経路とアルデヒド代謝の遺伝的相互作用解析” “ファン コニ貧血経路とアルデヒド代謝の遺伝的相互作用解析” 第35 回日本分子生物学会年会 ポスターよりワーク ショップへ採択 2012年12月 第35 回日本分子生物学会年会 ポスターよりワーク ショップへ採択 2012年12月 2012 Refereed Japanese Disclose to all
海野純也, 板谷(内田, 亜希子, 冨田純也, 井倉毅, 田岡万悟, 佐藤浩一, 胡桃坂仁志, 礒辺俊明, 高田穣 海野純也, 板谷(内田, 亜希子, 冨田純也, 井倉毅, 田岡万悟, 佐藤浩一, 胡桃坂仁志, 礒辺俊明, 高田穣 “DNA 鎖間架橋応答におけるファンコニ貧血経路によるCtIPの調節” “DNA 鎖間架橋応答におけるファンコニ貧血経路によるCtIPの調節” 第35 回日本分子生物学会年会 ポスターよりワークショップへ採択 2012 年12 月 第35 回日本分子生物学会年会 ポスターよりワークショップへ採択 2012 年12 月 2012 Japanese Disclose to all
細野嘉史, 関政幸, 阿部拓也, 石合正道, 武田俊一, 石井裕, 高田穣, 榎本武美 細野嘉史, 関政幸, 阿部拓也, 石合正道, 武田俊一, 石井裕, 高田穣, 榎本武美 “RecQLS ヘリガーゼのDNA クロスリンク修復における役割” “RecQLS ヘリガーゼのDNA クロスリンク修復における役割” 第35回日本分子生物学会年会 2012年12月 第35回日本分子生物学会年会 2012年12月 2012 Refereed Japanese Disclose to all
Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, Minoru Takata, Takemi Enomoto, Masayuki Seki Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, Minoru Takata, Takemi Enomoto, Masayuki Seki Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, Minoru Takata, Takemi Enomoto, Masayuki Seki The role of SNM1 family nucleases in etoposide-induced apoptosis The role of SNM1 family nucleases in etoposide-induced apoptosis The role of SNM1 family nucleases in etoposide-induced apoptosis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 410, 3, 568-573 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 410, 3, 568-573 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 410, 3, 568-573 2011/07 English Disclose to all
Kohei Nishimura, Masamichi Ishiai, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato Kanemaki Kohei Nishimura, Masamichi Ishiai, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato Kanemaki Kohei Nishimura, Masamichi Ishiai, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato Kanemaki Mcm8 and Mcm9 from a novel complex involved in resistance to DNA crosslinking agents. Mcm8 and Mcm9 from a novel complex involved in resistance to DNA crosslinking agents. Mcm8 and Mcm9 from a novel complex involved in resistance to DNA crosslinking agents. 日本分子生物学会第 34 回年会 2011 年12 月 横浜 日本分子生物学会第 34 回年会 2011 年12 月 横浜 日本分子生物学会第 34 回年会 2011 年12 月 横浜 2011 Refereed English Disclose to all
Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Takizawa, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Takizawa, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Koichi Sato, Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Takizawa, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka Histone chaperone activity of the FANCD2-FANCI complex and its importance in repair interstrand DNA crosslinks by the Fanconi anemia pathway. Histone chaperone activity of the FANCD2-FANCI complex and its importance in repair interstrand DNA crosslinks by the Fanconi anemia pathway. Histone chaperone activity of the FANCD2-FANCI complex and its importance in repair interstrand DNA crosslinks by the Fanconi anemia pathway. 日本分子生物学会第34 回年会 2011 年12 月 横浜 日本分子生物学会第34 回年会 2011 年12 月 横浜 日本分子生物学会第34 回年会 2011 年12 月 横浜 2011 Refereed English Disclose to all
J. Tomida, A. itaya, T. Shigechi, J. Unno, E. Uchida, R. Meetei, Y. Maehara, M. Ishiai, M. Takata J. Tomida, A. itaya, T. Shigechi, J. Unno, E. Uchida, R. Meetei, Y. Maehara, M. Ishiai, M. Takata J. Tomida, A. itaya, T. Shigechi, J. Unno, E. Uchida, R. Meetei, Y. Maehara, M. Ishiai, M. Takata “The Fancni Anemia Core Complex Promotes ATR Signaling” “The Fancni Anemia Core Complex Promotes ATR Signaling” “The Fancni Anemia Core Complex Promotes ATR Signaling” 23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM October 2011, Barcelona, Spain 23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM October 2011, Barcelona, Spain 23rd ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM October 2011, Barcelona, Spain 2011 Refereed English Disclose to all
Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John Eykelenboom, Pessina Fabio, Zhang Yanbin, Emi Uchida, Masamichi Ishiai, Noel Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John Eykelenboom, Pessina Fabio, Zhang Yanbin, Emi Uchida, Masamichi Ishiai, Noel Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John Eykelenboom, Pessina Fabio, Zhang Yanbin, Emi Uchida, Masamichi Ishiai, Noel Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata ATR-ATRIP kinase complex is responsible for triggering of the FA pathway. ATR-ATRIP kinase complex is responsible for triggering of the FA pathway. ATR-ATRIP kinase complex is responsible for triggering of the FA pathway. 日本分子生物学会第34 回年会 2011 年12 月 横浜 日本分子生物学会第34 回年会 2011 年12 月 横浜 日本分子生物学会第34 回年会 2011 年12 月 横浜 2011 Refereed English Disclose to all
茂地智子, 冨田純也, 佐藤浩一, 海野純也, 小林昌彦, 山本健一, 石合正道, 胡桃坂仁志, 前原善彦, 髙田穣 茂地智子, 冨田純也, 佐藤浩一, 海野純也, 小林昌彦, 山本健一, 石合正道, 胡桃坂仁志, 前原善彦, 髙田穣 「複製ストレスによるFA 経路の活性化には、ATRIP-ATR キナーゼが必須である」 「複製ストレスによるFA 経路の活性化には、ATRIP-ATR キナーゼが必須である」 第70 回日本癌学会学術総会 2011年10月 名古屋 第70 回日本癌学会学術総会 2011年10月 名古屋 2011 Refereed Japanese Disclose to all
髙田穣, 冨田純也, 板谷(内田, 亜希子, 茂地智子, 海野純也, 前原善彦, 石合正道 髙田穣, 冨田純也, 板谷(内田, 亜希子, 茂地智子, 海野純也, 前原善彦, 石合正道 「ファンコニ貧血 コア複合体によるATR -ATRIP キナーゼのクロマチン動態制御」 「ファンコニ貧血 コア複合体によるATR -ATRIP キナーゼのクロマチン動態制御」 第70 回日本癌学会学術総会 シンポジウム“Molecular basis of genome instability in cancer” 2011年10月 名古屋 第70 回日本癌学会学術総会 シンポジウム“Molecular basis of genome instability in cancer” 2011年10月 名古屋 2011 Refereed Japanese Disclose to all
石合正道, 佐藤浩一, 髙田穣, 胡桃坂仁志 石合正道, 佐藤浩一, 髙田穣, 胡桃坂仁志 「ファンコニ貧血DNA 修復経路の中心タンパク質FANCD2 はヌクレオソームアセンブリー活性を示す」 「ファンコニ貧血DNA 修復経路の中心タンパク質FANCD2 はヌクレオソームアセンブリー活性を示す」 第70 回日本癌学会学術総会 2011年10月 名古屋 第70 回日本癌学会学術総会 2011年10月 名古屋 2011 Refereed Japanese Disclose to all
海野純也, 板谷(内田, 亜希子, 冨田純也, 井倉毅, 高田穣 海野純也, 板谷(内田, 亜希子, 冨田純也, 井倉毅, 高田穣 「ファンコニ貧血蛋白質FAN CD2/FANCI 結合タンパク質のプロテオーム解析」 「ファンコニ貧血蛋白質FAN CD2/FANCI 結合タンパク質のプロテオーム解析」 第70回日本癌学会学術総会 2011年10月 名古屋 第70回日本癌学会学術総会 2011年10月 名古屋 2011 Refereed Japanese Disclose to all
Tomoko Shigechi, Junya Tomida, Emi Uchida, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai, Minoru Takata Tomoko Shigechi, Junya Tomida, Emi Uchida, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai, Minoru Takata Tomoko Shigechi, Junya Tomida, Emi Uchida, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai, Minoru Takata ATRIP is crutial for activation of the Fanconi anemia pathway through FANCI phosporylation. ATRIP is crutial for activation of the Fanconi anemia pathway through FANCI phosporylation. ATRIP is crutial for activation of the Fanconi anemia pathway through FANCI phosporylation. International Conference on Radiation and Cancer Biology at Nagasaki 20 ,10 2010 年2 月 長崎市 International Conference on Radiation and Cancer Biology at Nagasaki 20 ,10 2010 年2 月 長崎市 International Conference on Radiation and Cancer Biology at Nagasaki 20 ,10 2010 年2 月 長崎市 2010 Refereed English Disclose to all
佐藤浩一, 戸田和江, 古越聡, 越坂部晃永, 立和名博昭, 香川亘, 堂前直, 石合正道, 小布施力史, 木村宏, 高田穣, 胡桃坂仁志 佐藤浩一, 戸田和江, 古越聡, 越坂部晃永, 立和名博昭, 香川亘, 堂前直, 石合正道, 小布施力史, 木村宏, 高田穣, 胡桃坂仁志 「ファンコニ貧血原因遺伝子産物FANCD2 およびFANCI の複合体形成と機能解 析 「ファンコニ貧血原因遺伝子産物FANCD2 およびFANCI の複合体形成と機能解 析 第33 回日本分子生物学会年会 2010 年12 月 第33 回日本分子生物学会年会 2010 年12 月 2010 Refereed Japanese Disclose to all
石合正道, 島弘季, 田代聡, 高田穣 石合正道, 島弘季, 田代聡, 高田穣 「DNA ダメージにおけるArtemis の核内動態制御」 「DNA ダメージにおけるArtemis の核内動態制御」 第33 回日本分子生物 学会年会 2010 年12 月 第33 回日本分子生物 学会年会 2010 年12 月 2010 Refereed Japanese Disclose to all
石合正道, 島弘季, 田代聡, 高田穣 石合正道, 島弘季, 田代聡, 高田穣 「Artemis の核内動態制御機構の解析」 「Artemis の核内動態制御機構の解析」 日本放射線影響学会第53 回大 会 2010 年10 月 ワークショップ 日本放射線影響学会第53 回大 会 2010 年10 月 ワークショップ 2010 Refereed Japanese Disclose to all
佐藤浩一, 石合正道, 戸田和江, 古越聡, 越坂部晃永, 立和名博昭, 堂前直, 小布施力史, 木村宏, 高田穣, 胡桃坂仁志 佐藤浩一, 石合正道, 戸田和江, 古越聡, 越坂部晃永, 立和名博昭, 堂前直, 小布施力史, 木村宏, 高田穣, 胡桃坂仁志 「Fanconi 貧血原因遺伝子FANCD2 及びFANCI の機能解析」 「Fanconi 貧血原因遺伝子FANCD2 及びFANCI の機能解析」 第9 回核ダイナミクス研究会2010 年5 月 第9 回核ダイナミクス研究会2010 年5 月 2010 Refereed Japanese Disclose to all
足立淳, 鳴海良平, 佐野聖三, 久家貴寿, 白水崇, 松本雅記, 中山敬一, 茂木章, 井倉毅, 高田穣, 朝長毅 足立淳, 鳴海良平, 佐野聖三, 久家貴寿, 白水崇, 松本雅記, 中山敬一, 茂木章, 井倉毅, 高田穣, 朝長毅 「DNA 損傷応答ネットワークにおけるリン酸化・ユビキチン化修飾ダイナミクスのプロテオーム解析」 「DNA 損傷応答ネットワークにおけるリン酸化・ユビキチン化修飾ダイナミクスのプロテオーム解析」 第33 回日本分子生物学会年会第83 回「」本生化学会大会合同大会 2010 年12 月 第33 回日本分子生物学会年会第83 回「」本生化学会大会合同大会 2010 年12 月 2010 Refereed Japanese Disclose to all
Junya Tomida, Akiko Itaya, Emi Uchida, Tomoko shigechi, Masahiko kobayashi, ken-ichi Yamamoto, Masae Ikura, Tsuyoshi ikura, Agata Smogorzewska, Masamichi Ishiai, Minoru Takata Junya Tomida, Akiko Itaya, Emi Uchida, Tomoko shigechi, Masahiko kobayashi, ken-ichi Yamamoto, Masae Ikura, Tsuyoshi ikura, Agata Smogorzewska, Masamichi Ishiai, Minoru Takata Junya Tomida, Akiko Itaya, Emi Uchida, Tomoko shigechi, Masahiko kobayashi, ken-ichi Yamamoto, Masae Ikura, Tsuyoshi ikura, Agata Smogorzewska, Masamichi Ishiai, Minoru Takata FANCI phosphorylation by ATR kinase proceeds in a Rad17/TopBP 1 -independent manner. FANCI phosphorylation by ATR kinase proceeds in a Rad17/TopBP 1 -independent manner. FANCI phosphorylation by ATR kinase proceeds in a Rad17/TopBP 1 -independent manner. 第33 回日本分子生物学会年会第83 回 日本生化学会大会合同大 会 2010 年12 月 神戸市 第33 回日本分子生物学会年会第83 回 日本生化学会大会合同大 会 2010 年12 月 神戸市 第33 回日本分子生物学会年会第83 回 日本生化学会大会合同大 会 2010 年12 月 神戸市 2010 Refereed English Disclose to all
冨田純也, 板谷亜希子, 内田恵美, 茂地智子, 井倉正枝, 胡桃坂仁志, 井倉毅, 石合正道, 高田穣 冨田純也, 板谷亜希子, 内田恵美, 茂地智子, 井倉正枝, 胡桃坂仁志, 井倉毅, 石合正道, 高田穣 「DNA損傷応答におけるファンコニ貧血経路の活性化メカニズム」 「DNA損傷応答におけるファンコニ貧血経路の活性化メカニズム」 日本放射線影響学会第53 回大会 2010年10月 日本放射線影響学会第53 回大会 2010年10月 2010 Refereed Japanese Disclose to all
細野嘉史, 阿部卓也, 石合正道, 多田周右, 武田俊一, 高田穣, 関政幸, 榎本武美 細野嘉史, 阿部卓也, 石合正道, 多田周右, 武田俊一, 高田穣, 関政幸, 榎本武美 「DNA ヘリカーゼRECQL5 のDNA 組換え・修復における機能の解析」 「DNA ヘリカーゼRECQL5 のDNA 組換え・修復における機能の解析」 第33 回日本分子生物学会年会 2010 年12 月 第33 回日本分子生物学会年会 2010 年12 月 2010 Refereed Japanese Disclose to all
Hiroyuki Kitao, Indrajit Nanda, Yoshihiro Kakeji, Yoshihiko Maehara, Minoru Takata Hiroyuki Kitao, Indrajit Nanda, Yoshihiro Kakeji, Yoshihiko Maehara, Minoru Takata Hiroyuki Kitao, Indrajit Nanda, Yoshihiro Kakeji, Yoshihiko Maehara, Minoru Takata Genomic instability phenotype induced by loss of FancJ helicase function Genomic instability phenotype induced by loss of FancJ helicase function Genomic instability phenotype induced by loss of FancJ helicase function CANCER RESEARCH, 69 CANCER RESEARCH, 69 CANCER RESEARCH, 69 2009/05 English Research paper, summary (international conference) Disclose to all
Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichi Ishiai A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway. A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway. A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway. Oral presentation. Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium (Baltimore USA, Oct 1-4, 2009) Oral presentation. Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium (Baltimore USA, Oct 1-4, 2009) Oral presentation. Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium (Baltimore USA, Oct 1-4, 2009) 2009 Refereed English Disclose to all
冨田純也, 板谷亜希子, 茂地智子, 石合正道, 高田穣 冨田純也, 板谷亜希子, 茂地智子, 石合正道, 高田穣 FA NCI リン酸化によるファンコニ貧血コア複合体ユ ビキチンリガーゼの活性化 FA NCI リン酸化によるファンコニ貧血コア複合体ユ ビキチンリガーゼの活性化 第32 回日本分子生物学会年会、2009年12月、横浜市 第32 回日本分子生物学会年会、2009年12月、横浜市 2009 Refereed Japanese Disclose to all
石合正道, 冨田純也, 板谷亜希子, 高田穣 石合正道, 冨田純也, 板谷亜希子, 高田穣 細胞周期によるファンコニ貧血経路の活性化制御.「ゲノム不安定 性」 細胞周期によるファンコニ貧血経路の活性化制御.「ゲノム不安定 性」 第68 回日本癌学会学術総会 第68 回日本癌学会学術総会 2009 Refereed Japanese Disclose to all
石合正道, 島弘季, 田代聡, 高田穣 石合正道, 島弘季, 田代聡, 高田穣 Artemis の動態制御におけるリン酸化の役割 Artemis の動態制御におけるリン酸化の役割 日本放射線影響学会第52 回大会、2009年11月、広島市 日本放射線影響学会第52 回大会、2009年11月、広島市 2009 Refereed Japanese Disclose to all
石合正道, 北尾洋之, 冨田純也, 刀袮重信, 髙田穣 石合正道, 北尾洋之, 冨田純也, 刀袮重信, 髙田穣 「DT40 細胞システムを用いたDNA 損傷応答 研究」 「DT40 細胞システムを用いたDNA 損傷応答 研究」 日本放射線影響学会第51 回大会 2008 年11 月 北九州市 日本放射線影響学会第51 回大会 2008 年11 月 北九州市 2008 Refereed Japanese Disclose to all
冨田純也, 内田亜希子, 北尾洋之, 木下英司, 内田恵美, 小林昌彦, 山本健一, 小池透, 石合正道, 髙田穣 冨田純也, 内田亜希子, 北尾洋之, 木下英司, 内田恵美, 小林昌彦, 山本健一, 小池透, 石合正道, 髙田穣 「ファンコニ貧血経路の制御とFANCI タンパク質のリン酸化メカニズム」 「ファンコニ貧血経路の制御とFANCI タンパク質のリン酸化メカニズム」 第31 回日本分子生物学会年会、第81 回日本生化学会大会合同大会 2008 年12 月 神戸市 第31 回日本分子生物学会年会、第81 回日本生化学会大会合同大会 2008 年12 月 神戸市 2008 Refereed Japanese Disclose to all
刀袮重信, 丹田和恵, 須田泰司, 高田穣, 石合正道 刀袮重信, 丹田和恵, 須田泰司, 高田穣, 石合正道 「Ku70 とDNA 依存性蛋白キナーゼは、多くのアポトーシスに必須である」 「Ku70 とDNA 依存性蛋白キナーゼは、多くのアポトーシスに必須である」 第31 回日本分子生物学会年会、第81 回日本生化学会大会合同大会 2008 年12 月 神戸市 第31 回日本分子生物学会年会、第81 回日本生化学会大会合同大会 2008 年12 月 神戸市 2008 Refereed Japanese Disclose to all
北尾洋之, ナンタインドラジッド, 木野村愛子, 山添光芳, シュミットマイケル, 武田俊一, 吉永敬士, 前原喜彦, 高田穣 北尾洋之, ナンタインドラジッド, 木野村愛子, 山添光芳, シュミットマイケル, 武田俊一, 吉永敬士, 前原喜彦, 高田穣 「ヘリカーゼ欠損により生じるゲノム不安定性表現型」 「ヘリカーゼ欠損により生じるゲノム不安定性表現型」 第67 回日本癌学会学術総会 2008 年10 月 名古屋市 第67 回日本癌学会学術総会 2008 年10 月 名古屋市 2008 Refereed Japanese Disclose to all
Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor CLINICAL CANCER RESEARCH, 13, 11, 3431-3431 CLINICAL CANCER RESEARCH, 13, 11, 3431-3431 CLINICAL CANCER RESEARCH, 13, 11, 3431-3431 2007/06 English Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, Minoru Takata The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor [1] The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor [1] The epidermal growth factor receptor D761Y mutation and effect of tyrosine kinase inhibitor [1] Clinical Cancer Research, 13, 11, 3431 Clinical Cancer Research, 13, 11, 3431 Clinical Cancer Research, 13, 11, 3431 2007/06/01 English Rapid communication, short report, research note, etc.(scientific journal) Disclose to all
Akiko Uchida, Seiki Hirano, Hiroyuki Kitao, Atsuko Ogino, Kanmei Rai, Shinichi Toyooka, Nagio Takigawa, Masahiro Tabata, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Akiko Uchida, Seiki Hirano, Hiroyuki Kitao, Atsuko Ogino, Kanmei Rai, Shinichi Toyooka, Nagio Takigawa, Masahiro Tabata, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Akiko Uchida, Seiki Hirano, Hiroyuki Kitao, Atsuko Ogino, Kanmei Rai, Shinichi Toyooka, Nagio Takigawa, Masahiro Tabata, Minoru Takata, Katsuyuki Kiura, Mitsune Tanimoto Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation CANCER SCIENCE, 98, 3, 357-363 CANCER SCIENCE, 98, 3, 357-363 CANCER SCIENCE, 98, 3, 357-363 2007/03 English Disclose to all
石合正道, eidong Wang, 高田穣 石合正道, eidong Wang, 高田穣 「DNA 修復におけるファンコニ貧血経路の新規遺伝子FAAP100 の機能解析」 「DNA 修復におけるファンコニ貧血経路の新規遺伝子FAAP100 の機能解析」 第30 回分子生物学会 第80 回日本生化学会合同大会 2007 年12 月 第30 回分子生物学会 第80 回日本生化学会合同大会 2007 年12 月 2007 Refereed Japanese Disclose to all
刀袮重信, 丹田和恵, 湊川洋介, 高田穣, 石合正道 刀袮重信, 丹田和恵, 湊川洋介, 高田穣, 石合正道 「KU タンパクとDNA 依存性プロテインキナーゼ はDT40 細胞のアポートシスに必須である」 「KU タンパクとDNA 依存性プロテインキナーゼ はDT40 細胞のアポートシスに必須である」 第30 回分子生物学会 第80 回日本生化学会合同大会 2007 年12 月 第30 回分子生物学会 第80 回日本生化学会合同大会 2007 年12 月 2007 Refereed Japanese Disclose to all
高田穣, 石合正道, 木野村愛子, 北尾洋之 高田穣, 石合正道, 木野村愛子, 北尾洋之 「FANCI タンパク質のリン酸化とモノユビキチン化による ファンコニ貧血経路の抑制メカニズム」 「FANCI タンパク質のリン酸化とモノユビキチン化による ファンコニ貧血経路の抑制メカニズム」 第30 回分子生物学会 第80 回日本生化学会合同大会 ,2007 年12 月 第30 回分子生物学会 第80 回日本生化学会合同大会 ,2007 年12 月 2007 Refereed Japanese Disclose to all
高田 穣, 北尾洋之, 木野村愛子, 石合正道 高田 穣, 北尾洋之, 木野村愛子, 石合正道 「ファンコニ貧血コア複合体によるFANCD2/FANCI 複 合体のモノユビキチン化と相同組換え修復 「ファンコニ貧血コア複合体によるFANCD2/FANCI 複 合体のモノユビキチン化と相同組換え修復 ワークショップ 放射線DNA 損傷修復機構研究の最前線 放射線影響学会第50 回大会,2007 年11 月 ワークショップ 放射線DNA 損傷修復機構研究の最前線 放射線影響学会第50 回大会,2007 年11 月 2007 Refereed Japanese Disclose to all
石合正道, 高田穣 石合正道, 高田穣 「ファンコニ貧血経路の新規因子FAAP100 」 「ファンコニ貧血経路の新規因子FAAP100 」 第66 回日本癌学会学術総会,2007 年10 月 第66 回日本癌学会学術総会,2007 年10 月 2007 Refereed Japanese Disclose to all
高田穣, 北尾洋之, 木野村愛子, 石合正道 高田穣, 北尾洋之, 木野村愛子, 石合正道 「ファンコニ貧血コア複合体によるモノユビキチン化とDNA クロスリンク修復制御」 「ファンコニ貧血コア複合体によるモノユビキチン化とDNA クロスリンク修復制御」 第66 回日本癌学会学術総会,2007 年10 月 第66 回日本癌学会学術総会,2007 年10 月 2007 Refereed Japanese Disclose to all
豊岡 伸一, 青江 基, 佐野 由文, 伊達 洋至, 重松 久之, 内田 亜希子, 宗 淳一, 末久 弘, 小林 成行, 木浦 勝行, 高田 穣, 山根 正修 豊岡 伸一, 青江 基, 佐野 由文, 伊達 洋至, 重松 久之, 内田 亜希子, 宗 淳一, 末久 弘, 小林 成行, 木浦 勝行, 高田 穣, 山根 正修 PS-028-6 ゲフィチニブが奏効したBRAF遺伝子変異肺癌の経験(基礎研究2, 第24回日本呼吸器外科学会総会号) PS-028-6 ゲフィチニブが奏効したBRAF遺伝子変異肺癌の経験(基礎研究2, 第24回日本呼吸器外科学会総会号) 日本呼吸器外科学会雑誌, 21, 3 日本呼吸器外科学会雑誌, 21, 3 , 21, 3 2007 Japanese Disclose to all
高田 穣, 立入 誠司, 藤森 亮, 三木 義男, 武田 俊一 高田 穣, 立入 誠司, 藤森 亮, 三木 義男, 武田 俊一 高田 穣, 立入 誠司, 藤森 亮, 三木 義男, 武田 俊一 ニワトリBRCA2の全長クローニング 種を越えて保存された領域/モチーフの解析(Cloning of chicken homologue highlighted conserved domains and motifs in the tumour suppressor gene BRCA2) ニワトリBRCA2の全長クローニング 種を越えて保存された領域/モチーフの解析(Cloning of chicken homologue highlighted conserved domains and motifs in the tumour suppressor gene BRCA2) ニワトリBRCA2の全長クローニング 種を越えて保存された領域/モチーフの解析(Cloning of chicken homologue highlighted conserved domains and motifs in the tumour suppressor gene BRCA2) 日本癌学会総会記事, 60回, 98-98 日本癌学会総会記事, 60回, 98-98 日本癌学会総会記事, 60回, 98-98 2001/09 English Disclose to all
E Sonoda, M Takata, YM Yamashita, C Morrison, S Takeda E Sonoda, M Takata, YM Yamashita, C Morrison, S Takeda E Sonoda, M Takata, YM Yamashita, C Morrison, S Takeda Homologous DNA recombination in vertebrate cells Homologous DNA recombination in vertebrate cells Homologous DNA recombination in vertebrate cells PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 15, 8388-8394 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 15, 8388-8394 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 15, 8388-8394 2001/07 Refereed English Disclose to all
H Kurumizaka, S Ikawa, M Nakada, K Eda, W Kagawa, M Takata, S Takeda, S Yokoyama, T Shibata H Kurumizaka, S Ikawa, M Nakada, K Eda, W Kagawa, M Takata, S Takeda, S Yokoyama, T Shibata H Kurumizaka, S Ikawa, M Nakada, K Eda, W Kagawa, M Takata, S Takeda, S Yokoyama, T Shibata Homologous-pairing activity of the human DNA-repair proteins Xrcc3 center dot Rad51C Homologous-pairing activity of the human DNA-repair proteins Xrcc3 center dot Rad51C Homologous-pairing activity of the human DNA-repair proteins Xrcc3 center dot Rad51C PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 10, 5538-5543 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 10, 5538-5543 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98, 10, 5538-5543 2001/05 Refereed English Disclose to all
Toshio Noguchi, Kazuma Ikeda, Kazuhiko Yamamoto, Isao Yoshida, Atsuko Ashiba, Junjiro Tsuchiyama, Katsuji Shinagawa, Tadashi Yoshino, Minoru Takata, Mine Harada Toshio Noguchi, Kazuma Ikeda, Kazuhiko Yamamoto, Isao Yoshida, Atsuko Ashiba, Junjiro Tsuchiyama, Katsuji Shinagawa, Tadashi Yoshino, Minoru Takata, Mine Harada Toshio Noguchi, Kazuma Ikeda, Kazuhiko Yamamoto, Isao Yoshida, Atsuko Ashiba, Junjiro Tsuchiyama, Katsuji Shinagawa, Tadashi Yoshino, Minoru Takata, Mine Harada Antisense oligodeoxynucleotides to latent membrane protein 1 induce growth inhibition, apoptosis and Bcl-2 suppression in Epstein-Barr virus (EBV)-transformed B-lymphoblastoid cells, but not in EBV-positive natural killer cell lymphoma cells Antisense oligodeoxynucleotides to latent membrane protein 1 induce growth inhibition, apoptosis and Bcl-2 suppression in Epstein-Barr virus (EBV)-transformed B-lymphoblastoid cells, but not in EBV-positive natural killer cell lymphoma cells Antisense oligodeoxynucleotides to latent membrane protein 1 induce growth inhibition, apoptosis and Bcl-2 suppression in Epstein-Barr virus (EBV)-transformed B-lymphoblastoid cells, but not in EBV-positive natural killer cell lymphoma cells British Journal of Haematology, 114, 1, 84-92 British Journal of Haematology, 114, 1, 84-92 British Journal of Haematology, 114, 1, 84-92 2001 English Disclose to all
K Motoda, M Takata, K Kiura, Nakamura, I, M Harada K Motoda, M Takata, K Kiura, Nakamura, I, M Harada K Motoda, M Takata, K Kiura, Nakamura, I, M Harada SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line SHP-1/immunoreceptor tyrosine-based inhibition motif-independent inhibitory signalling through murine natural killer cell receptor Ly-49A in a transfected B-cell line IMMUNOLOGY, 100, 3, 370-377 IMMUNOLOGY, 100, 3, 370-377 IMMUNOLOGY, 100, 3, 370-377 2000/07 English Disclose to all
内海博司, 橋本光正, 田野かおり, 田野恵三, 桜井良憲, 高田穣, 武田俊一 内海博司, 橋本光正, 田野かおり, 田野恵三, 桜井良憲, 高田穣, 武田俊一 DNA2重鎖切断を制御する遺伝子ノックアウト細胞を用いての細胞周期感受性やRBEの検討 DNA2重鎖切断を制御する遺伝子ノックアウト細胞を用いての細胞周期感受性やRBEの検討 日本放射線影響学会第41回大会 日本放射線影響学会第41回大会 1998/12 Refereed Japanese Research paper, summary (national conference and other science council) Disclose to all
M.Takata, H.Kitao, A.kinomura, A, Smogorzewska, S.J.Elledge, M.Ishiai M.Takata, H.Kitao, A.kinomura, A, Smogorzewska, S.J.Elledge, M.Ishiai M.Takata, H.Kitao, A.kinomura, A, Smogorzewska, S.J.Elledge, M.Ishiai Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium. Oct 8-11. Chicago. Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium. Oct 8-11. Chicago. Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium. Oct 8-11. Chicago. Refereed English Disclose to all
足立淳, 鳴海良平, 佐野聖三, 久家貴寿, 白水 崇, 松本雅記, 中山敬一, 井倉正枝, 井倉 毅, 高田 穣, 朝長毅 足立淳, 鳴海良平, 佐野聖三, 久家貴寿, 白水 崇, 松本雅記, 中山敬一, 井倉正枝, 井倉 毅, 高田 穣, 朝長毅 「リン酸化プロテオミクスを用いた新規DNA 損傷初期応答キナーゼの探索」 「リン酸化プロテオミクスを用いた新規DNA 損傷初期応答キナーゼの探索」 第34 回日本分子生物学会年会 第34 回日本分子生物学会年会 Refereed Japanese Disclose to all

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Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Analysis of DNA damage repair by homologous recombination and the Fanconi anemia pathway.[Invited] Analysis of DNA damage repair by homologous recombination and the Fanconi anemia pathway. [Invited] Analysis of DNA damage repair by homologous recombination and the Fanconi anemia pathway. [Invited] International Particle Medicine Research Symposium IPMRS-2018-Takasaki International Particle Medicine Research Symposium IPMRS-2018-Takasaki International Particle Medicine Research Symposium IPMRS-2018-Takasaki 2018/10/30 English Oral presentation(invited, special) Disclose to all
Chromosome stress due to endogenous DNA damage and Fanconi anemia[Invited] Chromosome stress due to endogenous DNA damage and Fanconi anemia [Invited] Chromosome stress due to endogenous DNA damage and Fanconi anemia [Invited] 日本血液学会 JSH2018 日本血液学会 JSH2018 日本血液学会 JSH2018 2018/10/13 English Oral presentation(invited, special) Disclose to all
The ubiquitination pathway that recruits the Fanconi anemia nuclease scaffold SLX4/FANCP.[Invited] The ubiquitination pathway that recruits the Fanconi anemia nuclease scaffold SLX4/FANCP. [Invited] The ubiquitination pathway that recruits the Fanconi anemia nuclease scaffold SLX4/FANCP. [Invited] Korean Society for Molecular and Cellular Biology. Symposium “Molecular Mechanisms to preserve Genomic Integrity.” Korean Society for Molecular and Cellular Biology. Symposium “Molecular Mechanisms to preserve Genomic Integrity.” Korean Society for Molecular and Cellular Biology. Symposium “Molecular Mechanisms to preserve Genomic Integrity.” 2018/09/17 English Oral presentation(invited, special) Disclose to all
家族性のがんの話 家族性のがんの話 京都大学 研究連携基盤 丸の内セミナー 京都大学 研究連携基盤 丸の内セミナー 2018/09/07 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair.[Invited] RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair. [Invited] RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair. [Invited] 2018 IBS CONFERENCE IBS-KSMCB Conference on Genomic Interity &Cell Cycle June 2018 IBS CONFERENCE IBS-KSMCB Conference on Genomic Interity &Cell Cycle June 2018 IBS CONFERENCE IBS-KSMCB Conference on Genomic Interity &Cell Cycle June 2018/06/17 English Symposium workshop panel(nominated) Disclose to all
「ファンコニ貧血経路による染色体ストレス応答制御」 「新規ファンコニ貧血遺伝子RFWD3による相同組換え修復制御メカニズム」[Invited] 「ファンコニ貧血経路による染色体ストレス応答制御」 「新規ファンコニ貧血遺伝子RFWD3による相同組換え修復制御メカニズム」 [Invited] 神戸大学 大学院講義&セミナー 現代の生物学II 神戸大学 大学院講義&セミナー 現代の生物学II 2017/12/22 Japanese Oral presentation(invited, special) Disclose to all
Regulation of homologous recombination by a novel FA protein RFWD3/FANCW[Invited] Regulation of homologous recombination by a novel FA protein RFWD3/FANCW [Invited] Regulation of homologous recombination by a novel FA protein RFWD3/FANCW [Invited] National Taiwan University (Invited lecture) National Taiwan University (Invited lecture) National Taiwan University (Invited lecture) 2017/12/14 English Oral presentation(invited, special) Disclose to all
DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝子産物の関与 DNAタンパククロスリンク損傷修復におけるFANC及びTDP1遺伝子産物の関与 分子生物学会ConBio2017 分子生物学会ConBio2017 2017/12/07 Japanese Poster presentation Disclose to all
核内構造体によるDNA二本鎖切断応答制御機構の解明 核内構造体によるDNA二本鎖切断応答制御機構の解明 分子生物学会ConBio2017 分子生物学会ConBio2017 2017/12/07 Japanese Poster presentation Disclose to all
核内構造体に局在する因子による相同組換え修復制御 核内構造体に局在する因子による相同組換え修復制御 核内構造体に局在する因子による相同組換え修復制御 ConBio2017 分子生物学会ワークショップ ConBio2017 遺伝的組換えの分子メカニズムとその生理的機能と技術応用 ConBio2017 2017/12/07 Japanese Oral presentation(general) Disclose to all
複製ストレスにおける染色体脆弱部位へのR-Loop依存性FANCD2集積メカニズム. 複製ストレスにおける染色体脆弱部位へのR-Loop依存性FANCD2集積メカニズム. 複製ストレスにおける染色体脆弱部位へのR-Loop依存性FANCD2集積メカニズム. ConBio2017 2017年度生命科学系学会合同年次大会 ConBio2017 2017/12/07 Japanese Oral presentation(general) Disclose to all
ICL修復因子SLX4はRNF168依存的なユビキチン化経路を介して損傷部位に集積する.[Invited] ICL修復因子SLX4はRNF168依存的なユビキチン化経路を介して損傷部位に集積する. [Invited] 2017年度生命科学系学会合同年次大会ConBio2017, 第40回日本分子生物学会年会ワークショップ 2017年度生命科学系学会合同年次大会ConBio2017, 第40回日本分子生物学会年会ワークショップ 2017/12/07 Japanese Oral presentation(invited, special) Disclose to all
Replication stress induces R-loop-dependent accumulation of FANCD2 at large fragile genes. Replication stress induces R-loop-dependent accumulation of FANCD2 at large fragile genes. Replication stress induces R-loop-dependent accumulation of FANCD2 at large fragile genes. Radiation Biology Center International Symposium 2017 Radiation Biology Center International Symposium 2017 Radiation Biology Center International Symposium 2017 2017/12/04 English Poster presentation Disclose to all
RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair. RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair. RNF168 mediates the recruitment of SLX4 via ubiquitination during ICL repair. 3rd DNA Replication/Repair Structures and Cancer Conference. 3rd DNA Replication/Repair Structures and Cancer Conference. 3rd DNA Replication/Repair Structures and Cancer Conference. 2017/11/15 English Poster presentation Disclose to all
Regulation of homologous recombination by a novel FA protein RFWD3/FANCW. Regulation of homologous recombination by a novel FA protein RFWD3/FANCW. Regulation of homologous recombination by a novel FA protein RFWD3/FANCW. Shenzhen University. 1st International Symposium on Radiation Therapeutics and Biology (isRTB-2017) Shenzhen University. 1st International Symposium on Radiation Therapeutics and Biology (isRTB-2017) Shenzhen University. 1st International Symposium on Radiation Therapeutics and Biology (isRTB-2017) 2017/10/31 English Oral presentation(general) Disclose to all
ファンコニ貧血とゲノム損傷修復因子:患者サンプル解析による希少疾患病態解明を目指して[Invited] ファンコニ貧血とゲノム損傷修復因子:患者サンプル解析による希少疾患病態解明を目指して [Invited] 金沢大学薬学シンポジウム2017 金沢大学薬学シンポジウム2017 2017/10/06 Japanese Oral presentation(invited, special) Disclose to all
ファンコニ貧血の原因遺伝子探索と相同組換えの新規メカニズム[Invited] ファンコニ貧血の原因遺伝子探索と相同組換えの新規メカニズム [Invited] 名古屋大学 環境医学研究所 平成29年度 基盤医学特論 名古屋大学 環境医学研究所 平成29年度 基盤医学特論 2017/09/21 Japanese Oral presentation(invited, special) Disclose to all
Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia. Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia. Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia. 29th Annual Fanconi Anemia Scientific Symposium. 29th Annual Fanconi Anemia Scientific Symposium. 29th Annual Fanconi Anemia Scientific Symposium. 2017/09/14 English Oral presentation(general) Disclose to all
PARI regulates stalled replication fork processing to maintain genome stability upon replication stress in mice. PARI regulates stalled replication fork processing to maintain genome stability upon replication stress in mice. PARI regulates stalled replication fork processing to maintain genome stability upon replication stress in mice. 日本遺伝学会 第89回大会 日本遺伝学会 第89回大会 2017/09/13 English Oral presentation(general) Disclose to all
Regulation of homologous recombination by a novel FA protein RFWD3/FANCW.[Invited] Regulation of homologous recombination by a novel FA protein RFWD3/FANCW. [Invited] Regulation of homologous recombination by a novel FA protein RFWD3/FANCW. [Invited] Center for Genomic Integrity at UNIST invited lecture Center for Genomic Integrity at UNIST invited lecture Center for Genomic Integrity at UNIST invited lecture 2017/06/27 English Oral presentation(general) Disclose to all
Regulation of homologous recombination repair by a novel Fanconi anemia E3 ligase RFWD3/FANCW.[Invited] Regulation of homologous recombination repair by a novel Fanconi anemia E3 ligase RFWD3/FANCW. [Invited] Regulation of homologous recombination repair by a novel Fanconi anemia E3 ligase RFWD3/FANCW. [Invited] 6th US-Japan DNA Repair Meeting 6th US-Japan DNA Repair Meeting 6th US-Japan DNA Repair Meeting 2017/05/17 English Oral presentation(invited, special) Disclose to all
Regulation of homologous recombination by a novel FA protein RFWD3.[Invited] Regulation of homologous recombination by a novel FA protein RFWD3. [Invited] Regulation of homologous recombination by a novel FA protein RFWD3. [Invited] FEBS workshop Nucleotide excision repair and crosslink repair - from molecules to mankind FEBS workshop Nucleotide excision repair and crosslink repair - from molecules to mankind FEBS workshop Nucleotide excision repair and crosslink repair - from molecules to mankind 2017/05/07 English Oral presentation(invited, special) Disclose to all
Pathogenesis of Fanconi anemia: an update.[Invited] Pathogenesis of Fanconi anemia: an update. [Invited] Pathogenesis of Fanconi anemia: an update. [Invited] INTERNATIONAL CONFERENCE ON “ REVOLUTION OF LABORATORY MEDICINE IN MODERN BIOLOGY” INTERNATIONAL CONFERENCE ON “ REVOLUTION OF LABORATORY MEDICINE IN MODERN BIOLOGY” INTERNATIONAL CONFERENCE ON “ REVOLUTION OF LABORATORY MEDICINE IN MODERN BIOLOGY” 2017/02/15 English Oral presentation(invited, special) Disclose to all
新規ファンコニ貧血原因遺伝子であるRFWD3/FANCWの相同組換え修復における役割の解明[Invited] 新規ファンコニ貧血原因遺伝子であるRFWD3/FANCWの相同組換え修復における役割の解明 [Invited] 第8回群馬大 Genome Damage Discussion Group セミナー 第8回群馬大 Genome Damage Discussion Group セミナー 2016/12/21 Japanese Oral presentation(invited, special) Disclose to all
Genetic basis for childhood bone marrow failure and malignancies” A novel Fanconi anemia gene regulates ICL repair and homologous recombination.[Invited] Genetic basis for childhood bone marrow failure and malignancies” A novel Fanconi anemia gene regulates ICL repair and homologous recombination. [Invited] Genetic basis for childhood bone marrow failure and malignancies” A novel Fanconi anemia gene regulates ICL repair and homologous recombination. [Invited] 第58回日本小児血液・がん学会学術集会 シンポジウム 第58回日本小児血液・がん学会学術集会 シンポジウム 2016/12/15 English Oral presentation(invited, special) Disclose to all
DT40 ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死性作用を持つBiguanide 薬剤の作用機序の解析 DT40 ノックアウト細胞パネルを用いたグルコース枯渇下で細胞致死性作用を持つBiguanide 薬剤の作用機序の解析 放射線影響学会第59回大会 放射線影響学会第59回大会 2016/10/26 Japanese Poster presentation Disclose to all
損傷応答キナーゼ活性が相同組換え修復に与える影響 損傷応答キナーゼ活性が相同組換え修復に与える影響 放射線影響学会第59回大会 放射線影響学会第59回大会 2016/10/26 Japanese Oral presentation(general) Disclose to all
An E3 ligase RFWD3 is a critical component that facilitates RPA and RAD51 dynamics in homologous recombination.[Invited] An E3 ligase RFWD3 is a critical component that facilitates RPA and RAD51 dynamics in homologous recombination. [Invited] An E3 ligase RFWD3 is a critical component that facilitates RPA and RAD51 dynamics in homologous recombination. [Invited] 放射線影響学会第59回大会 ワークショップ「放射線・ゲノムストレスに対抗する多彩な生命システムの解明に向けて」 放射線影響学会第59回大会 ワークショップ「放射線・ゲノムストレスに対抗する多彩な生命システムの解明に向けて」 2016/10/26 English Oral presentation(invited, special) Disclose to all
相同組換えにおけるRPAおよびRAD51の動態制御はRFWD3によるユビキチン化に依存する。 相同組換えにおけるRPAおよびRAD51の動態制御はRFWD3によるユビキチン化に依存する。 第75回日本癌学会学術総会 シンポジウム18 がんにおける染色体・ゲノム不安定性の分子基盤。 第75回日本癌学会学術総会 シンポジウム18 がんにおける染色体・ゲノム不安定性の分子基盤。 2016/10/06 Japanese Oral presentation(general) Disclose to all
Common variable immunodeficiency caused by FANC mutations Common variable immunodeficiency caused by FANC mutations Common variable immunodeficiency caused by FANC mutations ESID2016 欧州免疫不全症学会 ESID2016 2016/09/21 English Poster presentation Disclose to all
Myelodysplastic syndrome and acute myeloid leukemia in Japanese Fanconi anemia patients. Myelodysplastic syndrome and acute myeloid leukemia in Japanese Fanconi anemia patients. Myelodysplastic syndrome and acute myeloid leukemia in Japanese Fanconi anemia patients. 28th Annual Fanconi Anemia research frund Scientific Symposium. 28th Annual Fanconi Anemia research frund Scientific Symposium. 28th Annual Fanconi Anemia research frund Scientific Symposium. 2016/09/15 English Oral presentation(general) Disclose to all
Novel Fanconi anemia E3 ligase RFWD3 promotes removal of both RPA and RAD51 from DNA damage sites during ICL repair. Novel Fanconi anemia E3 ligase RFWD3 promotes removal of both RPA and RAD51 from DNA damage sites during ICL repair. Novel Fanconi anemia E3 ligase RFWD3 promotes removal of both RPA and RAD51 from DNA damage sites during ICL repair. 28th Annual Fanconi Anemia research frund Scientific Symposium. 28th Annual Fanconi Anemia research frund Scientific Symposium. 28th Annual Fanconi Anemia research frund Scientific Symposium. 2016/09/15 English Oral presentation(general) Disclose to all
A novel Fanconi anemia E3 ubiquitin ligase RFWD3 functions in DNA repair. A novel Fanconi anemia E3 ubiquitin ligase RFWD3 functions in DNA repair. A novel Fanconi anemia E3 ubiquitin ligase RFWD3 functions in DNA repair. The 32nd International Symposium of Radiation Biology Center The 32nd International Symposium of Radiation Biology Center The 32nd International Symposium of Radiation Biology Center 2016/09/01 English Symposium workshop panel(nominated) Disclose to all
Novel Fanconi anemia E3 ligase RFWD3 regulates RPA and RAD51 degradation to facilitate homologous recombination and ICL repair. Novel Fanconi anemia E3 ligase RFWD3 regulates RPA and RAD51 degradation to facilitate homologous recombination and ICL repair. Novel Fanconi anemia E3 ligase RFWD3 regulates RPA and RAD51 degradation to facilitate homologous recombination and ICL repair. The 2016 Cold Spring Harbor Asia Conference The 2016 Cold Spring Harbor Asia Conference The 2016 Cold Spring Harbor Asia Conference 2016/06/13 English Poster presentation Disclose to all
新規ファンコニ貧血遺伝子RFWD3による相同組換え修復制御メカニズム[Invited] 新規ファンコニ貧血遺伝子RFWD3による相同組換え修復制御メカニズム [Invited] 九州大学 薬学部 藤田雅俊研究室 研究セミナー 九州大学 薬学部 藤田雅俊研究室 研究セミナー 2016 Japanese Oral presentation(invited, special) Disclose to all
複製ストレスによるFANCD2集積部位のゲノムワイド解析 複製ストレスによるFANCD2集積部位のゲノムワイド解析 第38回日本分子生物学会年会 第38回日本分子生物学会年会 2015/12/01 Japanese Oral presentation(general) Disclose to all
相同組換えにおけるRPA2のユビキチン化を介した分解 相同組換えにおけるRPA2のユビキチン化を介した分解 第38回日本分子生物学会年会 第38回日本分子生物学会年会 2015/12/01 Japanese Oral presentation(general) Disclose to all
UBE2T/FANCT is a novel FA gene identified in Japanese Fanconi anemia patients. UBE2T/FANCT is a novel FA gene identified in Japanese Fanconi anemia patients. UBE2T/FANCT is a novel FA gene identified in Japanese Fanconi anemia patients. 16th Ataxia-Teleangiectasia Workshop. 16th Ataxia-Teleangiectasia Workshop. 16th Ataxia-Teleangiectasia Workshop. 2015/10/11 English Oral presentation(general) Disclose to all
ファンコニ貧血と遺伝性乳がん卵巣がん:相同組換え欠損を基盤とした高発がん症候群[Invited] ファンコニ貧血と遺伝性乳がん卵巣がん:相同組換え欠損を基盤とした高発がん症候群 [Invited] 第74回日本癌学会 学術総会 第74回日本癌学会 学術総会 2015/10/08 Japanese Oral presentation(invited, special) Disclose to all
Perspective in Cancer Biology: Genetic Variations and Host-tumor Interactions. “DNA damage and repair in Fanconi anemia[Invited] がん生物学の展望:ゲノム変異とがん-宿主相互作用 [Invited] Perspective in Cancer Biology: Genetic Variations and Host-tumor Interactions. “DNA damage and repair in Fanconi anemia [Invited] 第2回IFOM−京都大学合同シンポジウム 第2回IFOM−京都大学合同シンポジウム 2015/10/06 Japanese Oral presentation(invited, special) Disclose to all
Genetic subtyping of Fanconi anemia in Japanese patients. Genetic subtyping of Fanconi anemia in Japanese patients. Genetic subtyping of Fanconi anemia in Japanese patients. 27th Annual Fanconi anemia research fund Scientific Symposium. 27th Annual Fanconi anemia research fund Scientific Symposium. 27th Annual Fanconi anemia research fund Scientific Symposium. 2015/09/17 English Poster presentation Disclose to all
Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia. Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia. Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia. 27th Annual Fanconi anemia research fund Scientific Symposium. 27th Annual Fanconi anemia research fund Scientific Symposium. 27th Annual Fanconi anemia research fund Scientific Symposium. 2015/09/17 English Oral presentation(general) Disclose to all
The Role of FANCD2 a central player of the Fanconi anemia pathway in DNA repair. The Role of FANCD2 a central player of the Fanconi anemia pathway in DNA repair. The Role of FANCD2 a central player of the Fanconi anemia pathway in DNA repair. ICRR2015 ICRR2015 ICRR2015 2015/05/25 English Poster presentation Disclose to all
FANCD2-dependent ATM phosphorylation after incision during DNA interstrand crosslink repair. FANCD2-dependent ATM phosphorylation after incision during DNA interstrand crosslink repair. FANCD2-dependent ATM phosphorylation after incision during DNA interstrand crosslink repair. ICRR2015 ICRR2015 ICRR2015 2015/05/25 English Poster presentation Disclose to all
Identification of UBE2T as a novel Fanconi anemia gene. Identification of UBE2T as a novel Fanconi anemia gene. Identification of UBE2T as a novel Fanconi anemia gene. ICRR2015 ICRR2015 ICRR2015 2015/05/25 English Oral presentation(general) Disclose to all
遺伝性DNA修復異常疾患:家族性乳がんとファンコニ貧血 遺伝性DNA修復異常疾患:家族性乳がんとファンコニ貧血 日本家族性腫瘍学会 第17回後期家族性腫瘍セミナー 日本家族性腫瘍学会 第17回後期家族性腫瘍セミナー 2015/03/08 Japanese Oral presentation(invited, special) Disclose to all
DNA鎖間架橋修復で働くFAN1ヌクレアーゼの生化学的機能解析 DNA鎖間架橋修復で働くFAN1ヌクレアーゼの生化学的機能解析 第37回日本分子生物学会年会 第37回日本分子生物学会年会 2014/11/25 Japanese Poster presentation Disclose to all
Fanconi貧血患者にみられるFANCD2変異体の機能解析 Fanconi貧血患者にみられるFANCD2変異体の機能解析 第37回日本分子生物学会年会 第37回日本分子生物学会年会 2014/11/25 Japanese Poster presentation Disclose to all
ゲノム編集酵素によるファンコニ貧血原因遺伝子FANCAのノックアウト細胞作製の試み ゲノム編集酵素によるファンコニ貧血原因遺伝子FANCAのノックアウト細胞作製の試み 第37回日本分子生物学会年会 第37回日本分子生物学会年会 2014/11/25 Japanese Poster presentation Disclose to all
ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析 ファンコニ貧血経路とそのキータンパク質FANCD2の機能解析 第37回日本分子生物学会年会 第37回日本分子生物学会年会 2014/11/25 Japanese Poster presentation Disclose to all
日本人ファンコニ貧血患者における新規原因遺伝子UBE2Tの同定 日本人ファンコニ貧血患者における新規原因遺伝子UBE2Tの同定 第37回日本分子生物学会年会 第37回日本分子生物学会年会 2014/11/25 Japanese Poster presentation Disclose to all
UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients UBE2T is a novel FA gene identified in Japanese Fanconi anemia patients The 9th 3R Symposium The 9th 3R Symposium The 9th 3R Symposium 2014/11/17 English Oral presentation(general) Disclose to all
Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene. Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene. Comprehensive analysis of Japanese Fanconi anemia (FA) patients has led to the identification of an E2 enzyme UBE2T as a novel FA gene. 日米修復会議 日米修復会議 2014/10/29 English Oral presentation(invited, special) Disclose to all
DNA鎖間架橋除去におけるFAN1ヌクレアーゼの役割 DNA鎖間架橋除去におけるFAN1ヌクレアーゼの役割 第87回日本生化学会大会 第87回日本生化学会大会 2014/10/15 Japanese Poster presentation Disclose to all
相同組換え修復の細胞周期依存性解析 相同組換え修復の細胞周期依存性解析 日本放射線影響学会第57回大会 日本放射線影響学会第57回大会 2014/10/01 Japanese Oral presentation(general) Disclose to all
Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype. Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype. Infant Japanese Fanconi anemia patients with the ALDH2-AA genotype. 26th Annual Fanconi Anemia Research Fund Scientific Symposium. 26th Annual Fanconi Anemia Research Fund Scientific Symposium. 26th Annual Fanconi Anemia Research Fund Scientific Symposium. 2014/09/18 English Oral presentation(general) Disclose to all
遺伝性DNA修復異常疾患:家族性乳がんとファンコニ貧血 遺伝性DNA修復異常疾患:家族性乳がんとファンコニ貧血 第17回家族性腫瘍セミナー 第17回家族性腫瘍セミナー 2014/08/24 Japanese Oral presentation(invited, special) Disclose to all
ファンコニ貧血症とDNA修復メカニズム ファンコニ貧血症とDNA修復メカニズム 第36回日本光医学・光生物学会シンポジウム 第36回日本光医学・光生物学会シンポジウム 2014/07/25 Japanese Oral presentation(general) Disclose to all
Roles of the Fanconi anemia protein FANCD2 in DNA cross link repair. Roles of the Fanconi anemia protein FANCD2 in DNA cross link repair. Roles of the Fanconi anemia protein FANCD2 in DNA cross link repair. International Conference, Kyoto, 2014 International Conference, Kyoto, 2014 International Conference, Kyoto, 2014 2014/02/04 English Oral presentation(general) Disclose to all
ICL 修復に重要なFAN1ヌクレアーゼの生化学的機能解析 ICL 修復に重要なFAN1ヌクレアーゼの生化学的機能解析 日本分子生物学会 日本分子生物学会 2013/12/03 Japanese Poster presentation Disclose to all
Mcm8-9 複合体はRad51 依存的鎖潜り込み反応後のDNA 伸長反応に関わる Mcm8-9 複合体はRad51 依存的鎖潜り込み反応後のDNA 伸長反応に関わる 分子生物学会ワークショップ 分子生物学会ワークショップ 2013/12/03 Japanese Oral presentation(general) Disclose to all
ファンコニ貧血原因遺伝子産物FANCD2 の示すヒストンシャペロン活性の生理的意義. ファンコニ貧血原因遺伝子産物FANCD2 の示すヒストンシャペロン活性の生理的意義. 分子生物学会ワークショップ 分子生物学会ワークショップ 2013/12/03 Japanese Oral presentation(general) Disclose to all
ゲノム不安定性と発がん ゲノム不安定性と発がん 第6回 岡山肺癌治療セミナー 第6回 岡山肺癌治療セミナー 2013/12/03 Japanese Oral presentation(invited, special) Disclose to all
Roles of the Fanconi anemia protein FANCD2 in DNA crosslink repair. Roles of the Fanconi anemia protein FANCD2 in DNA crosslink repair. Roles of the Fanconi anemia protein FANCD2 in DNA crosslink repair. 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 2013/11/28 English Oral presentation(general) Disclose to all
Fanconi anemia and Bloom syndrome proteins constitute a multifunctional complex to repair DNA damage. Fanconi anemia and Bloom syndrome proteins constitute a multifunctional complex to repair DNA damage. Fanconi anemia and Bloom syndrome proteins constitute a multifunctional complex to repair DNA damage. 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 2013/11/28 English Oral presentation(general) Disclose to all
ファンコニ貧血-家族性乳がん(FA-BRCA)経路によるゲノム安定性制御 ファンコニ貧血-家族性乳がん(FA-BRCA)経路によるゲノム安定性制御 聖マリアンナ医大 講演会 聖マリアンナ医大 講演会 2013/11/07 Japanese Oral presentation(invited, special) Disclose to all
ファンコニ貧血とゲノム損傷応答 ファンコニ貧血とゲノム損傷応答 京都大学 大学病院 血液内科セミナー 京都大学 大学病院 血液内科セミナー 2013/11/05 Japanese Oral presentation(invited, special) Disclose to all
Pluripotent cell models of Fanconi anemia identify the earliest pathological defect in human hemoangiogenic progenitors. Pluripotent cell models of Fanconi anemia identify the earliest pathological defect in human hemoangiogenic progenitors. Pluripotent cell models of Fanconi anemia identify the earliest pathological defect in human hemoangiogenic progenitors. 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 2013/10/24 English Oral presentation(general) Disclose to all
Modularized functions of the Fanconi anemia core complex. Modularized functions of the Fanconi anemia core complex. Modularized functions of the Fanconi anemia core complex. 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 2013/10/24 English Poster presentation Disclose to all
Involvement of the FA pathway in the maintenance of epigenetic stability near G-quadruplex forming DNA sequences. Involvement of the FA pathway in the maintenance of epigenetic stability near G-quadruplex forming DNA sequences. Involvement of the FA pathway in the maintenance of epigenetic stability near G-quadruplex forming DNA sequences. 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 2013/10/24 English Poster presentation Disclose to all
FANCD2 in chromatin anchors CtIP and regulates DNA end resection during crosslink repair. FANCD2 in chromatin anchors CtIP and regulates DNA end resection during crosslink repair. 25th Annual Fanconi anemia research fund Scientific Symposium 25th Annual Fanconi anemia research fund Scientific Symposium 2013/10/24 English Oral presentation(general) Disclose to all
DNA二重鎖切断修復欠損細胞におけるATM阻害の影響 DNA二重鎖切断修復欠損細胞におけるATM阻害の影響 放射線影響学会 放射線影響学会 2013/10/18 Japanese Oral presentation(general) Disclose to all
DNA二本鎖切断修復タンパク質欠損細胞のDNA複製阻害剤感受性 DNA二本鎖切断修復タンパク質欠損細胞のDNA複製阻害剤感受性 放射線影響学会 放射線影響学会 2013/10/18 Japanese Oral presentation(general) Disclose to all
放射線による細胞死研究の新展開」DNA損傷修復関連タンパクによるアポトーシス制御の二面性 放射線による細胞死研究の新展開」DNA損傷修復関連タンパクによるアポトーシス制御の二面性 放射線影響学会 放射線影響学会 2013/10/18 Japanese Oral presentation(general) Disclose to all
Clinical interaction between Japanese Fanconi anemia patients and aldehyde metabolism. Clinical interaction between Japanese Fanconi anemia patients and aldehyde metabolism. 日本血液学会 日本血液学会 2013/10/11 English Oral presentation(general) Disclose to all
ファンコニ貧血とDNAクロスリンク修復の分子機構 ー最近の進歩ー ファンコニ貧血とDNAクロスリンク修復の分子機構 ー最近の進歩ー 日本血液学会 日本血液学会 2013/10/11 Japanese Oral presentation(invited, special) Disclose to all
Fanconi anemia and genome instability Fanconi anemia and genome instability 京都大学大学院医学研究科 腫瘍コース コロキウム 京都大学大学院医学研究科 腫瘍コース コロキウム 2013/09/29 English Oral presentation(invited, special) Disclose to all
Fanconi貧血とゲノム不安定性 Fanconi貧血とゲノム不安定性 第13回血液フォーラム21 −造血不全− 特別講演 第13回血液フォーラム21 −造血不全− 特別講演 2013/05/18 Japanese Oral presentation(invited, special) Disclose to all
Mesodermal progenitors from reprogrammed FA cells were affected by ALDH2 enzymatic activity Mesodermal progenitors from reprogrammed FA cells were affected by ALDH2 enzymatic activity Mesodermal progenitors from reprogrammed FA cells were affected by ALDH2 enzymatic activity ASH highlights in Asia 2013 ASH highlights in Asia 2013 2013/03/24 English Poster presentation Disclose to all
Identification of interactors with the Fanconi anemia proteins FANCD2 using mass spectrometry. Keystone Symposia on Molecular and Cellular Biology, Genomic Instability and DNA Repair (X6). Identification of interactors with the Fanconi anemia proteins FANCD2 using mass spectrometry. Keystone Symposia on Molecular and Cellular Biology, Genomic Instability and DNA Repair (X6). ザ フェアモント バンフ スプリングス ザ フェアモント バンフ スプリングス 2013/03/13 English Poster presentation Disclose to all
ゲノムへのストレスとの戦い:生命の適応戦略を考える「内なる敵アルデヒドの攻撃からゲノムを守る-「体内浄化」と「傷の修理」の二つの戦略 ゲノムへのストレスとの戦い:生命の適応戦略を考える「内なる敵アルデヒドの攻撃からゲノムを守る-「体内浄化」と「傷の修理」の二つの戦略 第33回品川セミナー 第33回品川セミナー 2013/02 Japanese Oral presentation(general) Disclose to all
Pluripotent stem cell model of Seckel syndrome revealed that ATR regulates neural progenitors for orderly brain development. Pluripotent stem cell model of Seckel syndrome revealed that ATR regulates neural progenitors for orderly brain development. Pluripotent stem cell model of Seckel syndrome revealed that ATR regulates neural progenitors for orderly brain development. 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 2013 English Poster presentation Disclose to all
Biochemical analysis of ICL repair proteins, FANCI-FANCD2 complex. Biochemical analysis of ICL repair proteins, FANCI-FANCD2 complex. Biochemical analysis of ICL repair proteins, FANCI-FANCD2 complex. 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 2013 English Poster presentation Disclose to all
Effect of ATM kinase inhibitor on radiosensitivity of various DNA double strand break repair deficient cells. Effect of ATM kinase inhibitor on radiosensitivity of various DNA double strand break repair deficient cells. Effect of ATM kinase inhibitor on radiosensitivity of various DNA double strand break repair deficient cells. 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 29th RBC-NIRS INTERNATIONAL SYMPOSIUM 2013 English Poster presentation Disclose to all
DNA二重鎖切断修復における相同組換え修復の細胞周期依存性の解析 DNA二重鎖切断修復における相同組換え修復の細胞周期依存性の解析 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Poster presentation Disclose to all
RecQL5ヘリカーゼのDNAクロスリンク修復における役割 RecQL5ヘリカーゼのDNAクロスリンク修復における役割 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Poster presentation Disclose to all
FANCD2のモノユビキチン化機構の解析 FANCD2のモノユビキチン化機構の解析 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Poster presentation Disclose to all
DNA鎖間架橋応答におけるファンコニ貧血経路によるCtIPの調節 DNA鎖間架橋応答におけるファンコニ貧血経路によるCtIPの調節 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Oral presentation(general) Disclose to all
FANCD2のヒストンシャペロン活性がDNA修復機能に果たす役割 FANCD2のヒストンシャペロン活性がDNA修復機能に果たす役割 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Oral presentation(general) Disclose to all
ファンコニ貧血経路とアルデヒド代謝の遺伝的相互作用解析 ファンコニ貧血経路とアルデヒド代謝の遺伝的相互作用解析 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Oral presentation(general) Disclose to all
Mcm8とMcm9は複合体を形成し、DNA二本鎖架橋修復時に引き起こされる相同組換え修復において働く Mcm8とMcm9は複合体を形成し、DNA二本鎖架橋修復時に引き起こされる相同組換え修復において働く 第35回日本分子生物学会年会 第35回日本分子生物学会年会 2012/12 Japanese Oral presentation(general) Disclose to all
DNA損傷シグナルとファンコニ貧血経路 DNA損傷シグナルとファンコニ貧血経路 生体調節研究所セミナー講演 生体調節研究所セミナー講演 2012/11/15 Japanese Oral presentation(invited, special) Disclose to all
Histone chaperon activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair Histone chaperon activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair Histone chaperon activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair The 8th 3R Symposium The 8th 3R Symposium 2012/11 English Poster presentation Disclose to all
Molecular pathogenesis of Fanconi anemia Molecular pathogenesis of Fanconi anemia Molecular pathogenesis of Fanconi anemia 2012/11 English Oral presentation(general) Disclose to all
Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans Genetic interplay between the Fanconi anemia pathway and aldehyde metabolism in humans The 8th 3R Symposium The 8th 3R Symposium The 8th 3R Symposium 2012/11 English Oral presentation(general) Disclose to all
Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients 1st IFOM-KU joint symposium 1st IFOM-KU joint symposium 1st IFOM-KU joint symposium 2012/10/25 English Poster presentation Disclose to all
Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks. Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks. Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks. 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 2012/09/27 English Oral presentation(general) Disclose to all
FANCG functions independently of FANCA in the D1-D2-X3-Rad51C complex: Evidence for incomplete epistasis of FANCG/A FANCG functions independently of FANCA in the D1-D2-X3-Rad51C complex: Evidence for incomplete epistasis of FANCG/A FANCG functions independently of FANCA in the D1-D2-X3-Rad51C complex: Evidence for incomplete epistasis of FANCG/A 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 2012/09/27 English Oral presentation(general) Disclose to all
Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 24th ANNUAL Fanconi Anemia Research Fund SCIENTIFIC SYMPOSIUM 2012/09/27 English Oral presentation(general) Disclose to all
ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity 第71回日本癌学会学術総会 第71回日本癌学会学術総会 2012/09 English Poster presentation Disclose to all
Discovery of early-response kinases in DNA-damagesignaling using phosphoproteome analysis Discovery of early-response kinases in DNA-damagesignaling using phosphoproteome analysis 第71回日本癌学会学術総会 第71回日本癌学会学術総会 2012/09 English Poster presentation Disclose to all
Histone chaperone activity of FANCD2 plays an important role in the Fanconi anemia pathway Histone chaperone activity of FANCD2 plays an important role in the Fanconi anemia pathway Histone chaperone activity of FANCD2 plays an important role in the Fanconi anemia pathway 第71回日本癌学会学術総会 第71回日本癌学会学術総会 2012/09 English Oral presentation(general) Disclose to all
Genetic interplay between Fanconi anemia and aldehyde metabolism in humans Genetic interplay between Fanconi anemia and aldehyde metabolism in humans Genetic interplay between Fanconi anemia and aldehyde metabolism in humans 第71回日本癌学会学術総会 第71回日本癌学会学術総会 2012/09 English Oral presentation(general) Disclose to all
Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway Crosstalk signaling between checkpoint and the Fanconi anemia DNA repair pathway 第71回日本癌学会学術総会 第71回日本癌学会学術総会 第71回日本癌学会学術総会 2012/09 English Oral presentation(general) Disclose to all
New horizons of chromosome dynamics study New horizons of chromosome dynamics study New horizons of chromosome dynamics study 日本分子生物学会 第32回年会 日本分子生物学会 第32回年会 日本分子生物学会 第32回年会 2009/12/09 English Oral presentation(invited, special) Disclose to all
Analysis of the activation mechanism of the Fanconi anemia pathway. Analysis of the activation mechanism of the Fanconi anemia pathway. 日本分子生物学会 第32回年会 日本分子生物学会 第32回年会 2009/12/09 Japanese Oral presentation(invited, special) Disclose to all
DNA damage signaling in the Fanconi anemia pathogenesis DNA damage signaling in the Fanconi anemia pathogenesis DNA damage signaling in the Fanconi anemia pathogenesis 第51回 小児血液学会 血液プレジデンシャルシンポジウム「DNA damage response and hematological disorder」 第51回 小児血液学会 血液プレジデンシャルシンポジウム「DNA damage response and hematological disorder」 第51回 小児血液学会 血液プレジデンシャルシンポジウム「DNA damage response and hematological disorder」 2009/11/29 English Oral presentation(invited, special) Disclose to all
REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATHWAY. REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATHWAY. REGULATION OF CROSS-LINK REPAIR THROUGH THE FANCONI ANEMIA PATHWAY. The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund The Fortieth International Symposium of the Princess Takamatsu Cancer Research Fund 2009/11/10 English Oral presentation(invited, special) Disclose to all
高発がん遺伝病ファンコニ貧血の分子メカニズム 高発がん遺伝病ファンコニ貧血の分子メカニズム 第71回 日本血液学会学術集会 シンポジウム「小児血液腫瘍の発症リスクと先天異常」 第71回 日本血液学会学術集会 シンポジウム「小児血液腫瘍の発症リスクと先天異常」 2009/10/23 Japanese Oral presentation(invited, special) Disclose to all
Monoubiquitination- and phosphorylation-dependent activation of the Fanconi anemia pathway. Monoubiquitination- and phosphorylation-dependent activation of the Fanconi anemia pathway. Monoubiquitination- and phosphorylation-dependent activation of the Fanconi anemia pathway. The 3rd International Open Laboratory Workshop, “Recent Development in DNA Repair Studies” The 3rd International Open Laboratory Workshop, “Recent Development in DNA Repair Studies” The 3rd International Open Laboratory Workshop, “Recent Development in DNA Repair Studies” 2009/02/27 English Oral presentation(invited, special) Disclose to all
ファンコニ貧血経路によるゲノム安定化メカニズム ファンコニ貧血経路によるゲノム安定化メカニズム 第3回放射線防護研究センターシンポジウム「生き物はどのようにして放射線に立ち向かうか-DNA損傷応答と適応応答-」 第3回放射線防護研究センターシンポジウム「生き物はどのようにして放射線に立ち向かうか-DNA損傷応答と適応応答-」 放射線総合医学研究所 放射線総合医学研究所 2008/12/16 Japanese Oral presentation(invited, special) Disclose to all
DNA repair network deficiency and carcinogenesis DNA repair network deficiency and carcinogenesis DNA repair network deficiency and carcinogenesis 第67回日本癌学会学術総会 第67回日本癌学会学術総会 第67回日本癌学会学術総会 2008/10/28 English Oral presentation(invited, special) Disclose to all
ゲノムの安定性維持メカニズムとファンコニ貧血 ゲノムの安定性維持メカニズムとファンコニ貧血 第101回 小児血液腫瘍懇話会 第101回 小児血液腫瘍懇話会 2008/07/18 Japanese Oral presentation(invited, special) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
矢部普正, 高田穣, 村松秀樹 矢部普正, 高田穣, 村松秀樹 先天性骨髄不全症 診療ガイドライン 先天性骨髄不全症 診療ガイドライン 診断と治療社 診断と治療社 2017/10 Joint Work Disclose to all
石合正道, 高田 穣 石合正道, 高田 穣 放射線医科学の事典 放射線医科学の事典 医療科学社 医療科学社 2016/11 Joint Work Disclose to all
髙田 穰 髙田 穰 ゲノムを司るインターメア 非コードDNAの新たな展開 ゲノムを司るインターメア 非コードDNAの新たな展開 化学同人 化学同人 2015/11 Joint Work Disclose to all
稲野将二郎, 平明日香, 高田 穣 稲野将二郎, 平明日香, 高田 穣 家族性腫瘍学 —家族性腫瘍の最新研究動向—増刊号6 家族性腫瘍学 —家族性腫瘍の最新研究動向—増刊号6 日本臨床社 日本臨床社 2015/08 Disclose to all
Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata Masamichi Ishiai, Junya Tomida, Akiko Itaya, James Hejna, Minoru Takata DNA Replication, Recombination, and Repair. DNA Replication, Recombination, and Repair. DNA Replication, Recombination, and Repair. Springer Springer Springer 2015 Joint Work Disclose to all
Ishiai M, Uchida E, Takata M Ishiai M, Uchida E, Takata M Ishiai M, Uchida E, Takata M Methods Mol Biol. Methods Mol Biol. Methods Mol Biol. springer springer springer 2012 Joint Work Disclose to all
Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
日本白血病研究基金 荻村孝特別研究賞 公益信託 日本白血病研究基金 2009
ファンコニ貧血研究基金 発見賞 Fanconi anemia Research Fund Discovery Award ファンコニ貧血研究基金 Fanconi anemia Research Fund 2015/9
ファンコニ貧血研究基金 発見賞 Fanconi anemia Research Fund Discovery Award ファンコニ貧血研究基金 Fanconi anemia Research Fund 2017/9
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
科学研究費補助金・特定領域研究 Representative 染色体安定性と発がん抑制に関わるファンコニ貧血原因遺伝子群の機能解析 2005-2009
科学研究費補助金・基盤研究(B) Representative 複製フォーク停止に応答するチェックポイントキナーゼによるユビキチンシステム制御 2007-2011
厚生労働省がん研究助成金 Assignment 乳がん易罹患性の診断とそれに基づく予防に関する研究 2007-2007
科学研究費補助金・挑戦的萌芽研究 Representative ファンコニ貧血経路の真のターゲットは内因性ホルマリンによる蛋白質ゲノム架橋か? 2008-2010
厚生労働科学研究費補助金 Assignment ファンコニ貧血とその類縁疾患の生体試料収集に関する研究 2009-2009
受託研究・原子力安全研究推進事業 Assignment 発がん防御におけるクロマチン制御因子の役割 2010-2015
科学研究費助成事業・挑戦的萌芽研究 Representative 細胞周期特異的デグロンによる蛋白質発現制御と機能解析への応用 2011-2012
科学研究費補助金・新学術領域研究 Representative 複製フォークの安定化機構とその破綻による病態の解析 2011-2015
厚生労働科学研究費補助金 Assignment 稀少小児遺伝性血液疾患の迅速な原因究明及び診断・治療法の開発に関する研究 2011-2013
新学術領域 ゲノムを支える非コードDNA領域の機能 計画研究代表者 Representative 2011-2015
新学術領域研究(研究領域提案型) Representative 複製フォークの安定化機構とその破綻による病態の解析 2011-2015
基盤研究(B) Representative DNAクロスリンク修復におけるCtIPヌクレアーゼ制御機構の解析         2012-2014
挑戦的萌芽研究 Representative アルデヒド分解酵素の組織特異的発現解析とファンコニ貧血細胞における機能の解明 (平成26年度分) 2014/04/01-2015/03/31
新学術領域研究(研究領域提案型) Representative 複製フォークの安定化機構とその破綻による病態の解析 (平成26年度分) 2014/04/01-2015/03/31
基盤研究(B) Representative DNAクロスリンク修復におけるCtIPヌクレアーゼ制御機構の解析 (平成26年度分) 2014/04/01-2015/03/31
基盤研究(A) Representative 新規ファンコニ貧血遺伝子のハンティングと機能解析 (平成27年度分) 2015/04/01-2016/03/31
新学術領域研究(研究領域提案型) Representative 複製フォークの安定化機構とその破綻による病態の解析 (平成27年度分) 2015/04/01-2016/03/31
挑戦的萌芽研究 Representative アルデヒド分解酵素の組織特異的発現解析とファンコニ貧血細胞における機能の解明 (平成27年度分) 2015/04/01-2016/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) Assignment (平成27年度分) 2015/04/01-2016/03/31
基盤研究(A) Representative 新規ファンコニ貧血遺伝子のハンティングと機能解析 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(A) Representative 新規ファンコニ貧血遺伝子のハンティングと機能解析 (平成29年度分) 2017/04/01-2018/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) Assignment (平成29年度分) 2017/04/01-2018/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) Assignment 平成28年度分 2016/04/01-2017/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) Assignment (平成30年度分) 2018/04/01-2019/03/31
難治性疾患政策研究事業 Assignment (2019年度分) 2019/04/01-2020/03/31
基盤研究(B) Representative DNA損傷応答感受性を規定するSLFN11遺伝子の停止複製フォークにおける役割 (2020年度分) 2020/04/01-2021/03/31
挑戦的研究(萌芽) Representative エピジェネティックリプログラミングを支えるアルデヒド分解酵素のゲノム安定化機能 (2020年度分) 2020/04/01-2021/03/31
先天性骨髄不全症の登録システムの構築と診断基準・重症度分類・診断ガイドラインの確立に関する研究 Assignment (2020度分) 2020/04/01-2021/03/31

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External funds: other than those above
System Main person Title(Japanese) Title(English) Period
二国間交流事業共同研究・セミナー 高田 穰 ファンコニ貧血新規原因遺伝子の同定と解析への共同研究 (平成27年度分) 2015/04/01-2016/03/31
二国間交流事業共同研究・セミナー 高田 穰 ファンコニ貧血新規原因遺伝子の同定と解析への共同研究 (平成28年度分) 2016/04/01-2017/03/31
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
生命と放射線 Life and Radiation 前期 全学共通科目 2011/04-2012/03
放射線生物医学 Radiation Biology and Medicine 前期 工学研究科 2012/04-2013/03
生命と放射線 Life and Radiation 前期 全学共通科目 2012/04-2013/03
生命と放射線 Life and Radiation 前期 全学共通科目 2013/04-2014/03
放射線生物医学 Radiation Biology and Medicine 前期 工学研究科 2014/04-2015/03
生命と放射線 Life and Radiation 前期 全学共通科目 2014/04-2015/03
分子・生命環境論特別セミナー Special Seminar in Molecular Studies on Chemical and Biological Environments 通年 人間・環境学研究科 2015/04-2016/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2015/04-2016/03
生命と放射線 Life and Radiation 前期 全学共通科目 2015/04-2016/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2015/04-2016/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2015/04-2016/03
生命環境相関論特別演習2 Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2015/04-2016/03
生命環境相関論特別演習1 Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2015/04-2016/03
生物物理学 Molecular Biophysics 前期 工学部 2015/04-2016/03
相関環境学特別研究II Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2015/04-2016/03
相関環境学特別研究I Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2015/04-2016/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2015/04-2016/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2015/04-2016/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2016/04-2017/03
分子・生命環境論特別セミナー Special Seminar in Molecular Studies on Chemical and Biological Environments 通年 人間・環境学研究科 2016/04-2017/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2016/04-2017/03
放射線生物医学 Radiation Biology and Medicine 前期 工学研究科 2016/04-2017/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2016/04-2017/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2016/04-2017/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2016/04-2017/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2016/04-2017/03
生命環境相関論特別演習2 Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2016/04-2017/03
生命環境相関論特別演習1 Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2016/04-2017/03
相関環境学特別研究II Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2016/04-2017/03
相関環境学特別研究I Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2016/04-2017/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2016/04-2017/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2016/04-2017/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2016/04-2017/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2016/04-2017/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2017/04-2018/03
分子・生命環境論特別セミナー Special Seminar in Molecular Studies on Chemical and Biological Environments 通年 人間・環境学研究科 2017/04-2018/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2017/04-2018/03
染色体生命科学特論 Advanced Course in Chromosome Researches 前期集中 生命科学研究科 2017/04-2018/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2017/04-2018/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2017/04-2018/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2017/04-2018/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2017/04-2018/03
生命環境相関論特別演習2 Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2017/04-2018/03
生命環境相関論特別演習1 Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2017/04-2018/03
生物物理学 Molecular Biophysics 前期 工学部 2017/04-2018/03
相関環境学特別研究II Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2017/04-2018/03
相関環境学特別研究I Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2017/04-2018/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2017/04-2018/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2017/04-2018/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2017/04-2018/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2017/04-2018/03
分子・生命環境論特別セミナー Special Seminar in Molecular Studies on Chemical and Biological Environments 通年 人間・環境学研究科 2018/04-2019/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2018/04-2019/03
染色体生命科学特論 Advanced Course in Chromosome Researches 前期集中 生命科学研究科 2018/04-2019/03
特別実験及び演習A Experimental Course and Seminar A 前期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習A Experimental Course and Seminar A 後期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習B Experimental Course and Seminar B 前期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習B Experimental Course and Seminar B 後期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習C Experimental Course and Seminar C 前期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習C Experimental Course and Seminar C 後期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習D Experimental Course and Seminar D 前期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習D Experimental Course and Seminar D 後期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2018/04-2019/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2018/04-2019/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2018/04-2019/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2018/04-2019/03
生命環境相関論特別演習2 Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2018/04-2019/03
生命環境相関論特別演習1 Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2018/04-2019/03
生物物理学 Molecular Biophysics 前期 工学部 2018/04-2019/03
相関環境学特別研究II Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2018/04-2019/03
相関環境学特別研究I Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2018/04-2019/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2018/04-2019/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2018/04-2019/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2018/04-2019/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2018/04-2019/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2019/04-2020/03
分子・生命環境論特別セミナー Special Seminar in Molecular Studies on Chemical and Biological Environments 通年 人間・環境学研究科 2019/04-2020/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2019/04-2020/03
染色体生命科学特論 Advanced Course in Chromosome Researches 後期集中 生命科学研究科 2019/04-2020/03
特別実験及び演習A Experimental Course and Seminar A 前期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習A Experimental Course and Seminar A 後期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習B Experimental Course and Seminar B 前期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習B Experimental Course and Seminar B 後期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習C Experimental Course and Seminar C 前期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習C Experimental Course and Seminar C 後期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習D Experimental Course and Seminar D 前期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習D Experimental Course and Seminar D 後期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習 Experimental Course and Seminar 前期不定 生命科学研究科 2019/04-2020/03
特別実験及び演習 Experimental Course and Seminar 後期不定 生命科学研究科 2019/04-2020/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2019/04-2020/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2019/04-2020/03
生命環境相関論特別演習2 Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2019/04-2020/03
生命環境相関論特別演習1 Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2019/04-2020/03
生物物理学 Molecular Biophysics 前期 工学部 2019/04-2020/03
生物・生命科学入門 Introduction to Biology and Life Science 前期 全学共通科目 2019/04-2020/03
相関環境学特別研究II Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2019/04-2020/03
相関環境学特別研究I Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2019/04-2020/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2019/04-2020/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2019/04-2020/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2019/04-2020/03
高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2019/04-2020/03
ILASセミナー:ヒトは何故ガンになり、如何に立ち向かう … ILAS Seminar :Why we get cancer, and how we tackle it. 前期 全学共通科目 2020/04-2021/03
分子・生命環境論特別セミナー(博士科目) Special Seminar in Molecular Studies on Chemical and Biological Enviroments 通年 人間・環境学研究科 2020/04-2021/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習A Experimental Course and Seminar 前期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習B Experimental Course and Seminar 前期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習C Experimental Course and Seminar 前期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習D Experimental Course and Seminar 前期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習A Experimental Course and Seminar 後期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習B Experimental Course and Seminar 後期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習C Experimental Course and Seminar 後期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)特別実験及び演習D Experimental Course and Seminar 後期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2020/04-2021/03
(ゲノム損傷応答学)高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2020/04-2021/03
染色体生命科学特論 Advanced Course in Chromosome Researches 前期集中 生命科学研究科 2020/04-2021/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2020/04-2021/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2020/04-2021/03
生命環境相関論特別演習2(博士科目) Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2020/04-2021/03
生命環境相関論特別演習1(博士科目) Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2020/04-2021/03
生物物理学 Molecular Biophysics 前期 工学部 2020/04-2021/03
相関環境学特別研究II(博士科目) Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2020/04-2021/03
相関環境学特別研究I(博士科目) Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2020/04-2021/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2020/04-2021/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2020/04-2021/03
ILASセミナー:ヒトは何故ガンになり、如何に立ち向かう … ILAS Seminar :Why we get cancer, and how we cope with it? 前期 全学共通科目 2021/04-2022/03
分子・生命環境論特別セミナー(博士科目) Special Seminar in Molecular Studies on Chemical and Biological Enviroments 通年 人間・環境学研究科 2021/04-2022/03
ゲノム損傷応答学 DNA Damage Signaling 前期 人間・環境学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習A Experimental Course and Seminar 前期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習B Experimental Course and Seminar 前期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習C Experimental Course and Seminar 前期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習D Experimental Course and Seminar 前期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習A Experimental Course and Seminar 後期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習B Experimental Course and Seminar 後期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習C Experimental Course and Seminar 後期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)特別実験及び演習D Experimental Course and Seminar 後期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 前期不定 生命科学研究科 2021/04-2022/03
(ゲノム損傷応答学)高次生命科学特別演習 Advanced Experiments in Systemic Life Sciences 後期不定 生命科学研究科 2021/04-2022/03
染色体生命科学特論 Advanced Course in Chromosome Researches 前期集中 生命科学研究科 2021/04-2022/03
生命環境相関論演習1 Seminar in Environmental Molecular Life Science 1 前期 人間・環境学研究科 2021/04-2022/03
生命環境相関論演習2 Seminar in Environmental Molecular Life Science 2 後期 人間・環境学研究科 2021/04-2022/03
生命環境相関論特別演習2(博士科目) Advanced Seminar II in Environmental Molecular Life Sciences 後期 人間・環境学研究科 2021/04-2022/03
生命環境相関論特別演習1(博士科目) Advanced Seminar I in Environmental Molecular Life Sciences 前期 人間・環境学研究科 2021/04-2022/03
生物物理学 Molecular Biophysics 前期 工学部 2021/04-2022/03
相関環境学特別研究II(博士科目) Special Studies on Interdisciplinary environment II 通年 人間・環境学研究科 2021/04-2022/03
相関環境学特別研究I(博士科目) Special Studies on Interdisciplinary environment I 通年 人間・環境学研究科 2021/04-2022/03
相関環境学研究II Studies on interdisciplinary environment II 通年 人間・環境学研究科 2021/04-2022/03
相関環境学研究I Studies on interdisciplinary environment I 通年 人間・環境学研究科 2021/04-2022/03

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School management (title, position)
Title Period
京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員 2008/04/01-2011/03/31
京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員 2011/09/11-2013/09/10
全学情報セキュリティ委員会 委員 2013/04/01-2015/03/31
大学評価委員会 委員 2013/04/01-2015/03/31
吉田寮整備委員会委員 2014/02/05-2015/03/31
ヒトゲノム・遺伝子解析研究管理委員会 委員 2013/09/11-2015/09/10
大学評価委員会点検・評価実行委員会 委員 2013/04/01-
全学情報セキュリティ委員会 委員 2015/04/01-
ヒトゲノム・遺伝子解析研究管理委員会 委員 2015/09/11-2015/12/31
全学情報セキュリティ委員会 委員 2017/04/01-2019/03/31
放射線生物研究センター長 2013/04/01-2018/03/31
放射線生物研究センター長 2018/04/01-2019/03/31
放射性同位元素等専門委員会委員 2018/04/01-2023/03/31

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Faculty management (title, position)
Title Period
医学研究科等防犯カメラ設置運用委員会 2011/12/01-2013/11/30
医学研究科運営委員会 -2015/09/30
放射線生物研究センター人権委員会 -2018/03/31
放射線生物研究センター共同利用・共同研究専門委員会 2013/04/01-
放射線生物研究センター協議員会 -2018/03/31
放射線生物研究センター運営委員会 2013/04/01-
医学研究科等安全衛生委員会 2015/04/01-2017/03/31
放射線生物研究センター将来検討専門委員会 2015/04/01-2017/03/31
基盤運営委員会委員(南西地区) 2018/04/01-2019/03/31
附属放射線生物研究センター放射線障害防止委員会 2019/04/01-2019/07/31
放射線生物研究センターRI施設主任者 2018/04/01-2019/07/31
高次生命科学専攻副専攻長 2019/04/01-2020/03/31
高次生命科学専攻副専攻長 2020/04/01-2021/03/31
放射線障害防止委員会2号(放生研) 委員(主任者) 2020/04/01-
特定放射性同位元素防護委員会 委員長 2020/04/01-
改善委員会 委員 2020/04/01-2022/03/31
同窓会副会長 2020/04/01-2021/03/31
男女共同参画推進アクションプラン推進委員会 委員 2020/04/01-2021/03/31
高次生命科学専攻長 2021/04/01-2022/03/31
同窓会 理事 2021/04/01-2022/03/31
安全・環境保全委員会 2018/04/01-
放射線障害防止委員会3号 2019/08/01-2020/03/31

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