WOLTJEN KNUT

Last Update: 2021/06/30 16:05:00

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Name(Kanji/Kana/Abecedarium Latinum)
WOLTJEN KNUT/ウォルツェン クヌート/Woltjen, Knut
Primary Affiliation(Org1/Job title)
Center for iPS Cell Research and Application (CiRA)/Associate Professor
Contact Address
Type Address(Japanese) Address(English)
Office 〒606-8507 京都市 左京区 聖護院川原町53 日本 53 Kawahara-cho, Shogoin, Sakyo-ku Kyoto 〒606-8507 Japan
Phone
Type Number
Office 075-366-7000
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
Ph.D. University of Calgary
Language of Instruction
Language(japanese) Language(english) Code
日本語 Japanese jpn
英語 English eng
Personal Website(s) (URL(s))
URL
http://www.cira.kyoto-u.ac.jp/woltjen/
ORCID ID
https://orcid.org/0000-0003-2293-1183
researchmap URL
https://researchmap.jp/7000008096
Fields of research (key words)
Key words(Japanese) Key words(English)
DNA recombination, stem cell biology, regenerative medicine, genomics
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Thomas L Maurissen, Knut Woltjen Thomas L Maurissen, Knut Woltjen Thomas L Maurissen, Knut Woltjen Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation. Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation. Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation. Nature communications, 11, 1, 2876-2876 Nature communications, 11, 1, 2876-2876 Nature communications, 11, 1, 2876-2876 2020/06/08 Refereed English Research paper(scientific journal) Disclose to all
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L Maurissen, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Noriaki Kawakami, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L Maurissen, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Noriaki Kawakami, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L Maurissen, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Noriaki Kawakami, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Recapitulating the human segmentation clock with pluripotent stem cells. Recapitulating the human segmentation clock with pluripotent stem cells. Recapitulating the human segmentation clock with pluripotent stem cells. Nature, 580, 7801, 124-129 Nature, 580, 7801, 124-129 Nature, 580, 7801, 124-129 2020/04 Refereed English Research paper(scientific journal) Disclose to all
Sakakura M, Ohta S, Yagi M, Tanaka A, Norihide J, Woltjen K, Yamamoto T, Yamada Y Sakakura M, Ohta S, Yagi M, Tanaka A, Norihide J, Woltjen K, Yamamoto T, Yamada Y Sakakura M, Ohta S, Yagi M, Tanaka A, Norihide J, Woltjen K, Yamamoto T, Yamada Y Smarcb1 maintains the cellular identity and the chromatin landscapes of mouse embryonic stem cells. Smarcb1 maintains the cellular identity and the chromatin landscapes of mouse embryonic stem cells. Smarcb1 maintains the cellular identity and the chromatin landscapes of mouse embryonic stem cells. Biochemical and biophysical research communications, 519, 4, 705-713 Biochemical and biophysical research communications, 519, 4, 705-713 Biochemical and biophysical research communications, 519, 4, 705-713 2019/11 Refereed Disclose to all
Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura, Miki Nagai, Shiori Matsuo, David Lougheed, Hidetoshi Sakurai, Megumu K Saito, Guillaume Bourque, Knut Woltjen Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura, Miki Nagai, Shiori Matsuo, David Lougheed, Hidetoshi Sakurai, Megumu K Saito, Guillaume Bourque, Knut Woltjen Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura, Miki Nagai, Shiori Matsuo, David Lougheed, Hidetoshi Sakurai, Megumu K Saito, Guillaume Bourque, Knut Woltjen Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nature communications, 10, 1, 4856-4856 Nature communications, 10, 1, 4856-4856 Nature communications, 10, 1, 4856-4856 2019/10/24 Refereed English Research paper(scientific journal) Disclose to all
Arai, Hiroyuki N, Sato, Fuminori, Yamamoto, Takuya, Woltjen, Knut, Kiyonari, Hiroshi, Yoshimoto, Yuki, Shukunami, Chisa, Akiyama, Haruhiko, Kist, Ralf, Sehara-Fujisawa, Atsuko Arai, Hiroyuki N, Sato, Fuminori, Yamamoto, Takuya, Woltjen, Knut, Kiyonari, Hiroshi, Yoshimoto, Yuki, Shukunami, Chisa, Akiyama, Haruhiko, Kist, Ralf, Sehara-Fujisawa, Atsuko Arai, Hiroyuki N, Sato, Fuminori, Yamamoto, Takuya, Woltjen, Knut, Kiyonari, Hiroshi, Yoshimoto, Yuki, Shukunami, Chisa, Akiyama, Haruhiko, Kist, Ralf, Sehara-Fujisawa, Atsuko Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate CELL REPORTS, 29, 3, 603-+ CELL REPORTS, 29, 3, 603-+ CELL REPORTS, 29, 3, 603-+ 2019/10/15 Refereed Research paper(scientific journal) Disclose to all
Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Yutaka Matsuda, Kyoichi Hashimoto, Hirofumi Shibata, Masamitsu Sone, Norihide Jo, Kazuya Sekiguchi, Takatoshi Ohno, Haruhiko Akiyama, Katsuji Shimizu, Knut Woltjen, Manabu Ozawa, Junya Toguchida, Takuya Yamamoto, Yasuhiro Yamada Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Yutaka Matsuda, Kyoichi Hashimoto, Hirofumi Shibata, Masamitsu Sone, Norihide Jo, Kazuya Sekiguchi, Takatoshi Ohno, Haruhiko Akiyama, Katsuji Shimizu, Knut Woltjen, Manabu Ozawa, Junya Toguchida, Takuya Yamamoto, Yasuhiro Yamada Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Yutaka Matsuda, Kyoichi Hashimoto, Hirofumi Shibata, Masamitsu Sone, Norihide Jo, Kazuya Sekiguchi, Takatoshi Ohno, Haruhiko Akiyama, Katsuji Shimizu, Knut Woltjen, Manabu Ozawa, Junya Toguchida, Takuya Yamamoto, Yasuhiro Yamada Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Nature communications, 10, 1, 3999-3999 Nature communications, 10, 1, 3999-3999 Nature communications, 10, 1, 3999-3999 2019/09/05 Refereed English Disclose to all
Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. Stem cell reports, 12, 5, 1113-1128 Stem cell reports, 12, 5, 1113-1128 Stem cell reports, 12, 5, 1113-1128 2019/05 Refereed Disclose to all
Norihide Jo, Yuko Sogabe, Yosuke Yamada, Tomoyo Ukai, Harunobu Kagawa, Kanae Mitsunaga, Knut Woltjen, Yasuhiro Yamada Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y Norihide Jo, Yuko Sogabe, Yosuke Yamada, Tomoyo Ukai, Harunobu Kagawa, Kanae Mitsunaga, Knut Woltjen, Yasuhiro Yamada Platforms of in vivo genome editing with inducibleCas9for advanced cancer modeling Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Platforms of in vivo genome editing with inducibleCas9for advanced cancer modeling Cancer Science, 110, 3, 926-938 Cancer science, 110, 3, 926-938 Cancer Science, 110, 3, 926-938 2019/03 Refereed Research paper(scientific journal) Disclose to all
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K. Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K. Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, Mitsujiro Osawa, Megumu K. Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, Shiro Ikegawa, Satoko Sakurai, Shunsuke Kihara, Michiko Nakamura, Tomoko Matsumoto, Hiroyuki Yoshitomi, Makoto Ikeya, Takuya Yamamoto, Knut Woltjen, Miki Ebisuya, Junya Toguchida, Cantas Alev Modeling the Human Segmentation Clock with Pluripotent Stem Cells Modeling the Human Segmentation Clock with Pluripotent Stem Cells Modeling the Human Segmentation Clock with Pluripotent Stem Cells bioRxiv bioRxiv bioRxiv 2019/02 Disclose to all
Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. Stem cell reports, 12, 2, 319-332 Stem cell reports, 12, 2, 319-332 Stem cell reports, 12, 2, 319-332 2019/02 Refereed Disclose to all
Shin-Il Kim, Tomoko Matsumoto, Harunobu Kagawa, Michiko Nakamura, Ryoko Hirohata, Ayano Ueno, Maki Ohishi, Tetsushi Sakuma, Tomoyoshi Soga, Takashi Yamamoto, Knut Woltjen Shin-Il Kim, Tomoko Matsumoto, Harunobu Kagawa, Michiko Nakamura, Ryoko Hirohata, Ayano Ueno, Maki Ohishi, Tetsushi Sakuma, Tomoyoshi Soga, Takashi Yamamoto, Knut Woltjen Shin-Il Kim, Tomoko Matsumoto, Harunobu Kagawa, Michiko Nakamura, Ryoko Hirohata, Ayano Ueno, Maki Ohishi, Tetsushi Sakuma, Tomoyoshi Soga, Takashi Yamamoto, Knut Woltjen Microhomology-assisted scarless genome editing in human iPSCs Microhomology-assisted scarless genome editing in human iPSCs Microhomology-assisted scarless genome editing in human iPSCs Nature Communications, 9, 1, 939 Nature Communications, 9, 1, 939 Nature Communications, 9, 1, 939 2018/12/01 Refereed English Research paper(scientific journal) Disclose to all
Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto, Yasuhiro Yamada Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto, Yasuhiro Yamada Hirofumi Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda, Akito Tanaka, Tomoyo Ukai, Mio Kabata, Satoko Sakurai, Bunya Kuze, Knut Woltjen, Hironori Haga, Yatsuji Ito, Yoshiya Kawaguchi, Takuya Yamamoto, Yasuhiro Yamada In vivo reprogramming drives Kras-induced cancer development In vivo reprogramming drives Kras-induced cancer development In vivo reprogramming drives Kras-induced cancer development Nature Communications, 9, 1, 2081 Nature Communications, 9, 1, 2081 Nature Communications, 9, 1, 2081 2018/12/01 Refereed English Research paper(scientific journal) Disclose to all
Woltjen K, Bortvin A Woltjen K, Bortvin A Woltjen K, Bortvin A Editorial overview: Embroidering the canvas of life. Editorial overview: Embroidering the canvas of life. Editorial overview: Embroidering the canvas of life. Current opinion in genetics & development, 52, ii-iv Current opinion in genetics & development, 52, ii-iv Current opinion in genetics & development, 52, ii-iv 2018/10 Refereed Disclose to all
Ueda Tatsuki, Iriguchi Shoichi, Kawai Yohei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Seno Hiroshi, Hitoshi Yasumichi, Nakatsura Tetsuya, Tamada Koji, Kaneko Shin Ueda Tatsuki, Iriguchi Shoichi, Kawai Yohei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Seno Hiroshi, Hitoshi Yasumichi, Nakatsura Tetsuya, Tamada Koji, Kaneko Shin Ueda Tatsuki, Iriguchi Shoichi, Kawai Yohei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Seno Hiroshi, Hitoshi Yasumichi, Nakatsura Tetsuya, Tamada Koji, Kaneko Shin Generation of CAR-iPS-T cells expressing CD8 beta Generation of CAR-iPS-T cells expressing CD8 beta Generation of CAR-iPS-T cells expressing CD8 beta CANCER RESEARCH, 78, 13 CANCER RESEARCH, 78, 13 CANCER RESEARCH, 78, 13 2018/07 Refereed Disclose to all
Timothy J Kieffer, Knut Woltjen, Kenji Osafune, Daisuke Yabe, Nobuya Inagaki Timothy J Kieffer, Knut Woltjen, Kenji Osafune, Daisuke Yabe, Nobuya Inagaki Timothy J Kieffer, Knut Woltjen, Kenji Osafune, Daisuke Yabe, Nobuya Inagaki Beta-cell replacement strategies for diabetes Beta-cell replacement strategies for diabetes Beta-cell replacement strategies for diabetes Journal of Diabetes Investigation, 9, 3, 457-463 Journal of Diabetes Investigation, 9, 3, 457-463 Journal of Diabetes Investigation, 9, 3, 457-463 2018/05/01 Refereed English Disclose to all
Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita, Shinji Masui Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita, Shinji Masui Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, Akitsu Hotta, Takuya Yamamoto, Keisuke Okita, Shinji Masui Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Nature communications, 9, 1, 1387-1387 Nature communications, 9, 1, 1387-1387 Nature communications, 9, 1, 1387-1387 2018/04/11 Refereed English Research paper(scientific journal) Disclose to all
Ueda Tatsuki, Irigchi Shoich, Kawai Youhei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Tamada Koji, Nakatsura Tetsuya, Seno Hiroshi, Kaneko Shin Ueda Tatsuki, Irigchi Shoich, Kawai Youhei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Tamada Koji, Nakatsura Tetsuya, Seno Hiroshi, Kaneko Shin Ueda Tatsuki, Irigchi Shoich, Kawai Youhei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Tamada Koji, Nakatsura Tetsuya, Seno Hiroshi, Kaneko Shin iPSC-based CAR-T therapy targeting for GPC3 iPSC-based CAR-T therapy targeting for GPC3 iPSC-based CAR-T therapy targeting for GPC3 CANCER SCIENCE, 109, 294 CANCER SCIENCE, 109, 294 CANCER SCIENCE, 109, 294 2018/01 Refereed Disclose to all
Takayuki Kondo, Keiko Imamura, Misato Funayama, Kayoko Tsukita, Michiyo Miyake, Akira Ohta, Knut Woltjen, Masato Nakagawa, Takashi Asada, Tetsuaki Arai, Shinobu Kawakatsu, Yuishin Izumi, Ryuji Kaji, Nobuhisa Iwata, Haruhisa Inoue Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H Takayuki Kondo, Keiko Imamura, Misato Funayama, Kayoko Tsukita, Michiyo Miyake, Akira Ohta, Knut Woltjen, Masato Nakagawa, Takashi Asada, Tetsuaki Arai, Shinobu Kawakatsu, Yuishin Izumi, Ryuji Kaji, Nobuhisa Iwata, Haruhisa Inoue iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid beta Combination for Alzheimer's Disease iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid beta Combination for Alzheimer's Disease CELL REPORTS, 21, 8, 2304-2312 Cell reports, 21, 8, 2304-2312 CELL REPORTS, 21, 8, 2304-2312 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Yoshitake Sakai, Tomonori Nakamura, Yukihiro Yabuta, Fumio Nakaki, So Nagaoka, Knut Woltjen, Akitsu Hotta, Takuya Yamamoto, Mitinori Saitou Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Yoshitake Sakai, Tomonori Nakamura, Yukihiro Yabuta, Fumio Nakaki, So Nagaoka, Knut Woltjen, Akitsu Hotta, Takuya Yamamoto, Mitinori Saitou Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Yoshitake Sakai, Tomonori Nakamura, Yukihiro Yabuta, Fumio Nakaki, So Nagaoka, Knut Woltjen, Akitsu Hotta, Takuya Yamamoto, Mitinori Saitou Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell stem cell, 21, 4, 517-532 Cell stem cell, 21, 4, 517-532 Cell stem cell, 21, 4, 517-532 2017/10/05 Refereed English Disclose to all
Moe Hirosawa, Yoshihiko Fujita, Callum J. C. Parr, Karin Hayashi, Shunnichi Kashida, Akitsu Hotta, Knut Woltjen, Hirohide Saito Moe Hirosawa, Yoshihiko Fujita, Callum J. C. Parr, Karin Hayashi, Shunnichi Kashida, Akitsu Hotta, Knut Woltjen, Hirohide Saito Moe Hirosawa, Yoshihiko Fujita, Callum J. C. Parr, Karin Hayashi, Shunnichi Kashida, Akitsu Hotta, Knut Woltjen, Hirohide Saito Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch NUCLEIC ACIDS RESEARCH, 45, 13, e118 NUCLEIC ACIDS RESEARCH, 45, 13, e118 NUCLEIC ACIDS RESEARCH, 45, 13, e118 2017/07 Refereed English Research paper(scientific journal) Disclose to all
Masamitsu Sone, Nobuhiro Morone, Tomonori Nakamura, Akito Tanaka, Keisuke Okita, Knut Woltjen, Masato Nakagawa, John E. Heuser, Yasuhiro Yamada, Shinya Yamanaka, Takuya Yamamoto Masamitsu Sone, Nobuhiro Morone, Tomonori Nakamura, Akito Tanaka, Keisuke Okita, Knut Woltjen, Masato Nakagawa, John E. Heuser, Yasuhiro Yamada, Shinya Yamanaka, Takuya Yamamoto Masamitsu Sone, Nobuhiro Morone, Tomonori Nakamura, Akito Tanaka, Keisuke Okita, Knut Woltjen, Masato Nakagawa, John E. Heuser, Yasuhiro Yamada, Shinya Yamanaka, Takuya Yamamoto Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency Cell Metabolism, 25, 5, 1103-1117.e6 Cell Metabolism, 25, 5, 1103-1117.e6 Cell Metabolism, 25, 5, 1103-1117.e6 2017/05 Refereed Research paper(scientific journal) Disclose to all
Keiko Imamura, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean-Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryosuke Takahashi, Shinya Yamanaka, Haruhisa Inoue Keiko Imamura, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean-Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryosuke Takahashi, Shinya Yamanaka, Haruhisa Inoue Keiko Imamura, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean-Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryosuke Takahashi, Shinya Yamanaka, Haruhisa Inoue The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis SCIENCE TRANSLATIONAL MEDICINE, 9, 391 SCIENCE TRANSLATIONAL MEDICINE, 9, 391 SCIENCE TRANSLATIONAL MEDICINE, 9, 391 2017/05 Refereed English Research paper(scientific journal) Disclose to all
Kyoichi Hashimoto, Yosuke Yamada, Katsunori Semi, Masaki Yagi, Akito Tanaka, Fumiaki Itakura, Hitomi Aoki, Takahiro Kunisada, Knut Woltjen, Hironori Haga, Yoshiharu Sakai, Takuya Yamamoto, Yasuhiro Yamada Kyoichi Hashimoto, Yosuke Yamada, Katsunori Semi, Masaki Yagi, Akito Tanaka, Fumiaki Itakura, Hitomi Aoki, Takahiro Kunisada, Knut Woltjen, Hironori Haga, Yoshiharu Sakai, Takuya Yamamoto, Yasuhiro Yamada Kyoichi Hashimoto, Yosuke Yamada, Katsunori Semi, Masaki Yagi, Akito Tanaka, Fumiaki Itakura, Hitomi Aoki, Takahiro Kunisada, Knut Woltjen, Hironori Haga, Yoshiharu Sakai, Takuya Yamamoto, Yasuhiro Yamada Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 4, 758-763 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 4, 758-763 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 4, 758-763 2017/01 Refereed English Research paper(scientific journal) Disclose to all
河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 EWS-FLI1誘導性骨肉腫モデルによって骨分化障害が肉腫発生に重要な役割をもつことが明らかとなった EWS-FLI1誘導性骨肉腫モデルによって骨分化障害が肉腫発生に重要な役割をもつことが明らかとなった 日本整形外科学会雑誌, 90, 8, S1801-S1801 日本整形外科学会雑誌, 90, 8, S1801-S1801 , 90, 8, S1801-S1801 2016/08 Refereed Japanese Disclose to all
河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 マウスEWS/FLI1誘導性骨肉腫モデルが明らかとした肉腫発生に関わる重要事項 EWS/FLI1とcancer genomeがもたらす細胞分化異常 マウスEWS/FLI1誘導性骨肉腫モデルが明らかとした肉腫発生に関わる重要事項 EWS/FLI1とcancer genomeがもたらす細胞分化異常 日本整形外科学会雑誌, 90, 6, S1215-S1215 日本整形外科学会雑誌, 90, 6, S1215-S1215 , 90, 6, S1215-S1215 2016/06 Refereed Japanese Disclose to all
Fabian Oceguera-Yanez, Shin-Il Kim, Tomoko Matsumoto, Ghee Wan Tan, Long Xiang, Takeshi Hatani, Takayuki Kondo, Makoto Ikeya, Yoshinori Yoshida, Haruhisa Inoue, Knut Woltjen Fabian Oceguera-Yanez, Shin-Il Kim, Tomoko Matsumoto, Ghee Wan Tan, Long Xiang, Takeshi Hatani, Takayuki Kondo, Makoto Ikeya, Yoshinori Yoshida, Haruhisa Inoue, Knut Woltjen Fabian Oceguera-Yanez, Shin-Il Kim, Tomoko Matsumoto, Ghee Wan Tan, Long Xiang, Takeshi Hatani, Takayuki Kondo, Makoto Ikeya, Yoshinori Yoshida, Haruhisa Inoue, Knut Woltjen Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives METHODS, 101, 43-55 METHODS, 101, 43-55 METHODS, 101, 43-55 2016/05 Refereed English Research paper(scientific journal) Disclose to all
Knut Woltjen, Takashi Yamamoto, Chikara Kokubu, Junji Takeda Knut Woltjen, Takashi Yamamoto, Chikara Kokubu, Junji Takeda Knut Woltjen, Takashi Yamamoto, Chikara Kokubu, Junji Takeda Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara GENES TO CELLS, 21, 5, 392-395 GENES TO CELLS, 21, 5, 392-395 GENES TO CELLS, 21, 5, 392-395 2016/05 Refereed English Research paper(scientific journal) Disclose to all
Shingo Komura, Katsunori Semi, Fumiaki Itakura, Hirofumi Shibata, Takatoshi Ohno, Akitsu Hotta, Knut Woltjen, Takuya Yamamoto, Haruhiko Akiyama, Yasuhiro Yamada Shingo Komura, Katsunori Semi, Fumiaki Itakura, Hirofumi Shibata, Takatoshi Ohno, Akitsu Hotta, Knut Woltjen, Takuya Yamamoto, Haruhiko Akiyama, Yasuhiro Yamada Shingo Komura, Katsunori Semi, Fumiaki Itakura, Hirofumi Shibata, Takatoshi Ohno, Akitsu Hotta, Knut Woltjen, Takuya Yamamoto, Haruhiko Akiyama, Yasuhiro Yamada An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development STEM CELL REPORTS, 6, 4, 592-606 STEM CELL REPORTS, 6, 4, 592-606 STEM CELL REPORTS, 6, 4, 592-606 2016/04 Refereed English Research paper(scientific journal) Disclose to all
河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 河村 真吾, 蝉 克憲, 板倉 史晃, 柴田 博史, 堀田 秋津, Woltjen Knut, 山本 拓也, 大野 貴敏, 秋山 治彦, 山田 泰広 マウスEWS/FLI1誘導性骨肉腫モデルが明らかとした肉腫発生に関わる重要事項 EWS/FLI1とcancer genomeがもたらす細胞分化異常 マウスEWS/FLI1誘導性骨肉腫モデルが明らかとした肉腫発生に関わる重要事項 EWS/FLI1とcancer genomeがもたらす細胞分化異常 日本整形外科学会雑誌, 90, 2, S145-S145 日本整形外科学会雑誌, 90, 2, S145-S145 , 90, 2, S145-S145 2016/03 Refereed Japanese Disclose to all
Knut Woltjen, Fabian Oceguera-Yanez, Harunobu Kagawa, Shin-Il Kim Knut Woltjen, Fabian Oceguera-Yanez, Harunobu Kagawa, Shin-Il Kim Knut Woltjen, Fabian Oceguera-Yanez, Harunobu Kagawa, Shin-Il Kim At the conflux of human genome engineering and induced pluripotency At the conflux of human genome engineering and induced pluripotency At the conflux of human genome engineering and induced pluripotency Genome Editing, 45-64 Genome Editing, 45-64 Genome Editing, 45-64 2016/01/01 Refereed English Disclose to all
Woltjen K, Kim SI, Nagy A Woltjen K, Kim SI, Nagy A Woltjen K, Kim SI, Nagy A The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. Methods in molecular biology (Clifton, N.J.), 1357, 1-22 Methods in molecular biology (Clifton, N.J.), 1357, 1-22 Methods in molecular biology (Clifton, N.J.), 1357, 1-22 2016 Refereed Disclose to all
Emi Shoji, Knut Woltjen, Hidetoshi Sakurai Emi Shoji, Knut Woltjen, Hidetoshi Sakurai Emi Shoji, Knut Woltjen, Hidetoshi Sakurai Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.), 1353, 89-99 Methods in molecular biology (Clifton, N.J.), 1353, 89-99 Methods in molecular biology (Clifton, N.J.), 1353, 89-99 2016 Refereed English Research paper(scientific journal) Disclose to all
田口 純平, 蝉 克憲, 山田 洋介, 大西 紘太郎, 柴田 博史, 光永 佳奈枝, Woltjen Knut, 山田 泰広 田口 純平, 蝉 克憲, 山田 洋介, 大西 紘太郎, 柴田 博史, 光永 佳奈枝, Woltjen Knut, 山田 泰広 田口 純平, 蝉 克憲, 山田 洋介, 大西 紘太郎, 柴田 博史, 光永 佳奈枝, Woltjen Knut, 山田 泰広 生体における未熟なリプログラミングの終結は絨毛がんを誘発する(Premature termination of reprogramming in vivo leads to choriocarcinoma development) 生体における未熟なリプログラミングの終結は絨毛がんを誘発する(Premature termination of reprogramming in vivo leads to choriocarcinoma development) 生体における未熟なリプログラミングの終結は絨毛がんを誘発する(Premature termination of reprogramming in vivo leads to choriocarcinoma development) 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回, [2P1078]-[2P1078] 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回, [2P1078]-[2P1078] 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回, [2P1078]-[2P1078] 2015/12 Refereed English Disclose to all
Sakura Tamaki, Makoto Fukuta, Kazuya Sekiguchi, Yonghui Jin, Sanae Nagata, Kazuo Hayakawa, Sho Hineno, Takeshi Okamoto, Makoto Watanabe, Knut Woltjen, Makoto Ikeya, Tomohisa Kato, Junya Toguchida Sakura Tamaki, Makoto Fukuta, Kazuya Sekiguchi, Yonghui Jin, Sanae Nagata, Kazuo Hayakawa, Sho Hineno, Takeshi Okamoto, Makoto Watanabe, Knut Woltjen, Makoto Ikeya, Tomohisa Kato, Junya Toguchida Sakura Tamaki, Makoto Fukuta, Kazuya Sekiguchi, Yonghui Jin, Sanae Nagata, Kazuo Hayakawa, Sho Hineno, Takeshi Okamoto, Makoto Watanabe, Knut Woltjen, Makoto Ikeya, Tomohisa Kato, Junya Toguchida SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier PLOS ONE, 10, 11, e0142991 PLOS ONE, 10, 11, e0142991 PLOS ONE, 10, 11, e0142991 2015/11 Refereed English Research paper(scientific journal) Disclose to all
Eleni Chantzoura, Stavroula Skylaki, Sergio Menendez, Shin-Il Kim, Anna Johnsson, Sten Linnarsson, Knut Woltjen, Ian Chambers, Keisuke Kaji Eleni Chantzoura, Stavroula Skylaki, Sergio Menendez, Shin-Il Kim, Anna Johnsson, Sten Linnarsson, Knut Woltjen, Ian Chambers, Keisuke Kaji Eleni Chantzoura, Stavroula Skylaki, Sergio Menendez, Shin-Il Kim, Anna Johnsson, Sten Linnarsson, Knut Woltjen, Ian Chambers, Keisuke Kaji Reprogramming Roadblocks Are System Dependent Reprogramming Roadblocks Are System Dependent Reprogramming Roadblocks Are System Dependent STEM CELL REPORTS, 5, 3, 350-364 STEM CELL REPORTS, 5, 3, 350-364 STEM CELL REPORTS, 5, 3, 350-364 2015/09 Refereed English Research paper(scientific journal) Disclose to all
Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 2015/08 Refereed Research paper(scientific journal) Disclose to all
Yonghui Jin, Hassan Elalaf, Makoto Watanabe, Sakura Tamaki, Sho Hineno, Kazuhito Matsunaga, Knut Woltjen, Yukiko Kobayashi, Sanae Nagata, Makoto Ikeya, Tomohisa Kato, Takeshi Okamoto, Shuichi Matsuda, Junya Toguchida Yonghui Jin, Hassan Elalaf, Makoto Watanabe, Sakura Tamaki, Sho Hineno, Kazuhito Matsunaga, Knut Woltjen, Yukiko Kobayashi, Sanae Nagata, Makoto Ikeya, Tomohisa Kato, Takeshi Okamoto, Shuichi Matsuda, Junya Toguchida Yonghui Jin, Hassan Elalaf, Makoto Watanabe, Sakura Tamaki, Sho Hineno, Kazuhito Matsunaga, Knut Woltjen, Yukiko Kobayashi, Sanae Nagata, Makoto Ikeya, Tomohisa Kato, Takeshi Okamoto, Shuichi Matsuda, Junya Toguchida Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes PLOS ONE, 10, 7, e0131998 PLOS ONE, 10, 7, e0131998 PLOS ONE, 10, 7, e0131998 2015/07 Refereed English Research paper(scientific journal) Disclose to all
Shin-Il Kim, Fabian Oceguera-Yanez, Ryoko Hirohata, Sara Linker, Keisuke Okita, Yasuhiro Yamada, Takuya Yamamoto, Shinya Yamanaka, Knut Woltjen Shin-Il Kim, Fabian Oceguera-Yanez, Ryoko Hirohata, Sara Linker, Keisuke Okita, Yasuhiro Yamada, Takuya Yamamoto, Shinya Yamanaka, Knut Woltjen Shin-Il Kim, Fabian Oceguera-Yanez, Ryoko Hirohata, Sara Linker, Keisuke Okita, Yasuhiro Yamada, Takuya Yamamoto, Shinya Yamanaka, Knut Woltjen KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency STEM CELL REPORTS, 4, 4, 727-743 STEM CELL REPORTS, 4, 4, 727-743 STEM CELL REPORTS, 4, 4, 727-743 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Mitsuhiro Matsuda, Makito Koga, Knut Woltjen, Eisuke Nishida, Miki Ebisuya Mitsuhiro Matsuda, Makito Koga, Knut Woltjen, Eisuke Nishida, Miki Ebisuya Mitsuhiro Matsuda, Makito Koga, Knut Woltjen, Eisuke Nishida, Miki Ebisuya Synthetic lateral inhibition governs cell-type bifurcation with robust ratios Synthetic lateral inhibition governs cell-type bifurcation with robust ratios Synthetic lateral inhibition governs cell-type bifurcation with robust ratios NATURE COMMUNICATIONS, 6, 6195 NATURE COMMUNICATIONS, 6, 6195 NATURE COMMUNICATIONS, 6, 6195 2015/02 Refereed English Research paper(scientific journal) Disclose to all
Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K WOLTJEN KNUT Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Methods in Molecular Biology, 1357, 111-131 Methods in Molecular Biology, 1357, 111-131 Methods in Molecular Biology, 1357, 111-131 2015 Refereed English Research paper(scientific journal) Disclose to all
Kotaro Ohnishi, Katsunori Semi, Takuya Yamamoto, Masahito Shimizu, Akito Tanaka, Kanae Mitsunaga, Keisuke Okita, Kenji Osafune, Yuko Arioka, Toshiyuki Maeda, Hidenobu Soejima, Hisataka Moriwaki, Shinya Yamanaka, Knut Woltjen, Yasuhiro Yamada Kotaro Ohnishi, Katsunori Semi, Takuya Yamamoto, Masahito Shimizu, Akito Tanaka, Kanae Mitsunaga, Keisuke Okita, Kenji Osafune, Yuko Arioka, Toshiyuki Maeda, Hidenobu Soejima, Hisataka Moriwaki, Shinya Yamanaka, Knut Woltjen, Yasuhiro Yamada Kotaro Ohnishi, Katsunori Semi, Takuya Yamamoto, Masahito Shimizu, Akito Tanaka, Kanae Mitsunaga, Keisuke Okita, Kenji Osafune, Yuko Arioka, Toshiyuki Maeda, Hidenobu Soejima, Hisataka Moriwaki, Shinya Yamanaka, Knut Woltjen, Yasuhiro Yamada Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation CELL, 156, 4, 663-677 CELL, 156, 4, 663-677 CELL, 156, 4, 663-677 2014/02 Refereed English Research paper(scientific journal) Disclose to all
Tetsushi Sakuma, Knut Woltjen Tetsushi Sakuma, Knut Woltjen Tetsushi Sakuma, Knut Woltjen Nuclease-mediated genome editing: At the front-line of functional genomics technology Nuclease-mediated genome editing: At the front-line of functional genomics technology Nuclease-mediated genome editing: At the front-line of functional genomics technology DEVELOPMENT GROWTH & DIFFERENTIATION, 56, 1, 2-13 DEVELOPMENT GROWTH & DIFFERENTIATION, 56, 1, 2-13 DEVELOPMENT GROWTH & DIFFERENTIATION, 56, 1, 2-13 2014/01 Refereed English Disclose to all
Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD WOLTJEN KNUT Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell, 13, 5, 564-576 Cell Stem Cell, 13, 5, 564-576 Cell Stem Cell, 13, 5, 564-576 2013/11 Refereed English Research paper(scientific journal) Disclose to all
Akihiro Yamashita, Shiying Liu, Knut Woltjen, Bradley Thomas, Guoliang Meng, Akitsu Hotta, Kazutoshi Takahashi, James Ellis, Shinya Yamanaka, Derrick E. Rancourt Akihiro Yamashita, Shiying Liu, Knut Woltjen, Bradley Thomas, Guoliang Meng, Akitsu Hotta, Kazutoshi Takahashi, James Ellis, Shinya Yamanaka, Derrick E. Rancourt Akihiro Yamashita, Shiying Liu, Knut Woltjen, Bradley Thomas, Guoliang Meng, Akitsu Hotta, Kazutoshi Takahashi, James Ellis, Shinya Yamanaka, Derrick E. Rancourt Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells SCIENTIFIC REPORTS, 3, 1978 SCIENTIFIC REPORTS, 3, 1978 SCIENTIFIC REPORTS, 3, 1978 2013/06 Refereed English Research paper(scientific journal) Disclose to all
Akihito Tanaka, Knut Woltjen, Katsuya Miyake, Akitsu Hotta, Makoto Ikeya, Takuya Yamamoto, Tokiko Nishino, Emi Shoji, Atsuko Sehara-Fujisawa, Yasuko Manabe, Nobuharu Fujii, Kazunori Hanaoka, Takumi Era, Satoshi Yamashita, Ken-ichi Isobe, En Kimura, Hidetoshi Sakurai Akihito Tanaka, Knut Woltjen, Katsuya Miyake, Akitsu Hotta, Makoto Ikeya, Takuya Yamamoto, Tokiko Nishino, Emi Shoji, Atsuko Sehara-Fujisawa, Yasuko Manabe, Nobuharu Fujii, Kazunori Hanaoka, Takumi Era, Satoshi Yamashita, Ken-ichi Isobe, En Kimura, Hidetoshi Sakurai Akihito Tanaka, Knut Woltjen, Katsuya Miyake, Akitsu Hotta, Makoto Ikeya, Takuya Yamamoto, Tokiko Nishino, Emi Shoji, Atsuko Sehara-Fujisawa, Yasuko Manabe, Nobuharu Fujii, Kazunori Hanaoka, Takumi Era, Satoshi Yamashita, Ken-ichi Isobe, En Kimura, Hidetoshi Sakurai Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro PLOS ONE, 8, 4, e61540 PLOS ONE, 8, 4, e61540 PLOS ONE, 8, 4, e61540 2013/04 Refereed English Research paper(scientific journal) Disclose to all
Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Efficient TALEN construction and evaluation methods for human cell and animal applications Efficient TALEN construction and evaluation methods for human cell and animal applications Efficient TALEN construction and evaluation methods for human cell and animal applications GENES TO CELLS, 18, 4, 315-326 GENES TO CELLS, 18, 4, 315-326 GENES TO CELLS, 18, 4, 315-326 2013/04 Refereed English Research paper(scientific journal) Disclose to all
Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-Ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-Ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Tetsushi Sakuma, Sayaka Hosoi, Knut Woltjen, Ken-Ichi Suzuki, Keiko Kashiwagi, Housei Wada, Hiroshi Ochiai, Tatsuo Miyamoto, Narudo Kawai, Yasunori Sasakura, Shinya Matsuura, Yasushi Okada, Atsuo Kawahara, Shigeo Hayashi, Takashi Yamamoto Efficient TALEN construction and evaluation methods for human cell and animal applications Efficient TALEN construction and evaluation methods for human cell and animal applications Efficient TALEN construction and evaluation methods for human cell and animal applications Genes to Cells, 18, 4, 315-326 Genes to Cells, 18, 4, 315-326 Genes to Cells, 18, 4, 315-326 2013/04 English Research paper(scientific journal) Disclose to all
Kazuo Hayakawa, Makoto Ikeya, Makoto Fukuta, Knut Woltjen, Sakura Tamaki, Naoko Takahara, Tomohisa Kato, Shingo Sato, Takanobu Otsuka, Junya Toguchida Kazuo Hayakawa, Makoto Ikeya, Makoto Fukuta, Knut Woltjen, Sakura Tamaki, Naoko Takahara, Tomohisa Kato, Shingo Sato, Takanobu Otsuka, Junya Toguchida Kazuo Hayakawa, Makoto Ikeya, Makoto Fukuta, Knut Woltjen, Sakura Tamaki, Naoko Takahara, Tomohisa Kato, Shingo Sato, Takanobu Otsuka, Junya Toguchida Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 432, 4, 713-719 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 432, 4, 713-719 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 432, 4, 713-719 2013/03 Refereed English Research paper(scientific journal) Disclose to all
Iacovos P. Michael, Claudio Monetti, Anthony C. Chiu, Puzheng Zhang, Takeshi Baba, Koichiro Nishino, Siamak Agha-Mohammadi, Knut Woltjen, Hoon-Ki Sung, Andras Nagy Iacovos P. Michael, Claudio Monetti, Anthony C. Chiu, Puzheng Zhang, Takeshi Baba, Koichiro Nishino, Siamak Agha-Mohammadi, Knut Woltjen, Hoon-Ki Sung, Andras Nagy Iacovos P. Michael, Claudio Monetti, Anthony C. Chiu, Puzheng Zhang, Takeshi Baba, Koichiro Nishino, Siamak Agha-Mohammadi, Knut Woltjen, Hoon-Ki Sung, Andras Nagy Highly efficient site-specific transgenesis in cancer cell lines Highly efficient site-specific transgenesis in cancer cell lines Highly efficient site-specific transgenesis in cancer cell lines MOLECULAR CANCER, 11, 89 MOLECULAR CANCER, 11, 89 MOLECULAR CANCER, 11, 89 2012/12 Refereed English Research paper(scientific journal) Disclose to all
Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (Stem Cell Rev and Rep, 10.1007/s12015-011-9239-5) Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (Stem Cell Rev and Rep, 10.1007/s12015-011-9239-5) Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (Stem Cell Rev and Rep, 10.1007/s12015-011-9239-5) Stem Cell Reviews and Reports, 8, 2, 546 Stem Cell Reviews and Reports, 8, 2, 546 Stem Cell Reviews and Reports, 8, 2, 546 2012/06 Refereed English Research paper(scientific journal) Disclose to all
Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O'Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O. Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R. Hughes, Peter W. Zandstra, Andras Nagy, Jeffrey L. Wrana, Benjamin J. Blencowe Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O'Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O. Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R. Hughes, Peter W. Zandstra, Andras Nagy, Jeffrey L. Wrana, Benjamin J. Blencowe Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O'Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O. Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R. Hughes, Peter W. Zandstra, Andras Nagy, Jeffrey L. Wrana, Benjamin J. Blencowe An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming CELL, 147, 1, 132-146 CELL, 147, 1, 132-146 CELL, 147, 1, 132-146 2011/09 Refereed English Research paper(scientific journal) Disclose to all
Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts STEM CELL REVIEWS AND REPORTS, 7, 3, 693-702 STEM CELL REVIEWS AND REPORTS, 7, 3, 693-702 STEM CELL REVIEWS AND REPORTS, 7, 3, 693-702 2011/09 Refereed English Research paper(scientific journal) Disclose to all
Claudio Monetti, Koichiro Nishino, Steffen Biechele, Puzheng Zhang, Takeshi Baba, Knut Woltjen, Andras Nagy Claudio Monetti, Koichiro Nishino, Steffen Biechele, Puzheng Zhang, Takeshi Baba, Knut Woltjen, Andras Nagy Claudio Monetti, Koichiro Nishino, Steffen Biechele, Puzheng Zhang, Takeshi Baba, Knut Woltjen, Andras Nagy PhiC31 integrase facilitates genetic approaches combining multiple recombinases PhiC31 integrase facilitates genetic approaches combining multiple recombinases PhiC31 integrase facilitates genetic approaches combining multiple recombinases METHODS, 53, 4, 380-385 METHODS, 53, 4, 380-385 METHODS, 53, 4, 380-385 2011/04 Refereed English Research paper(scientific journal) Disclose to all
Woltjen K, Hamalainen R, Kibschull M, Mileikovsky M, Nagy A Woltjen K, Hamalainen R, Kibschull M, Mileikovsky M, Nagy A Woltjen K, Hamalainen R, Kibschull M, Mileikovsky M, Nagy A Transposon-based production of genetically unmodified induced pluripotent stem cells from human embryonic fibroblasts Transposon-based production of genetically unmodified induced pluripotent stem cells from human embryonic fibroblasts Transposon-based production of genetically unmodified induced pluripotent stem cells from human embryonic fibroblasts Methods in Molecular Biology 767 (87):103 Methods in Molecular Biology 767 (87):103 Methods in Molecular Biology 767 (87):103 2011 Refereed English Disclose to all
Knut Woltjen, Riikka Hämäläinen, Mark Kibschull, Maria Mileikovsky, Andras Nagy Knut Woltjen, Riikka Hämäläinen, Mark Kibschull, Maria Mileikovsky, Andras Nagy Knut Woltjen, Riikka Hämäläinen, Mark Kibschull, Maria Mileikovsky, Andras Nagy Transgene-free production of pluripotent stem cells using piggyBac transposons Transgene-free production of pluripotent stem cells using piggyBac transposons Transgene-free production of pluripotent stem cells using piggyBac transposons Methods in Molecular Biology, 767, 87-103 Methods in Molecular Biology, 767, 87-103 Methods in Molecular Biology, 767, 87-103 2011 Refereed English Research paper(scientific journal) Disclose to all
Payman Samavarchi-Tehrani, Azadeh Golipour, Laurent David, Hoon-Ki Sung, Tobias A. Beyer, Alessandro Datti, Knut Woltjen, Andras Nagy, Jeffrey L. Wrana Payman Samavarchi-Tehrani, Azadeh Golipour, Laurent David, Hoon-Ki Sung, Tobias A. Beyer, Alessandro Datti, Knut Woltjen, Andras Nagy, Jeffrey L. Wrana Payman Samavarchi-Tehrani, Azadeh Golipour, Laurent David, Hoon-Ki Sung, Tobias A. Beyer, Alessandro Datti, Knut Woltjen, Andras Nagy, Jeffrey L. Wrana Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming CELL STEM CELL, 7, 1, 64-77 CELL STEM CELL, 7, 1, 64-77 CELL STEM CELL, 7, 1, 64-77 2010/07 Refereed English Research paper(scientific journal) Disclose to all
Kathryn Sciabica, Knut Woltjen, Akitsu Hotta Kathryn Sciabica, Knut Woltjen, Akitsu Hotta Kathryn Sciabica, Knut Woltjen, Akitsu Hotta Obtaining Pluripotency Biomarker Signatures Obtaining Pluripotency Biomarker Signatures Obtaining Pluripotency Biomarker Signatures GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 30, 3, 20-21 GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 30, 3, 20-21 GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 30, 3, 20-21 2010/02 English Research paper(scientific journal) Disclose to all
Knut Woltjen, William L. Stanford Knut Woltjen, William L. Stanford Knut Woltjen, William L. Stanford Inhibition of Tgf-beta Signaling Improves Mouse Fibroblast Reprogramming Inhibition of Tgf-beta Signaling Improves Mouse Fibroblast Reprogramming Inhibition of Tgf-beta Signaling Improves Mouse Fibroblast Reprogramming CELL STEM CELL, 5, 5, 457-458 CELL STEM CELL, 5, 5, 457-458 CELL STEM CELL, 5, 5, 457-458 2009/11 Refereed English Disclose to all
James O'Malley, Knut Woltjen, Keisuke Kaji James O'Malley, Knut Woltjen, Keisuke Kaji James O'Malley, Knut Woltjen, Keisuke Kaji New strategies to generate induced pluripotent stem cells New strategies to generate induced pluripotent stem cells New strategies to generate induced pluripotent stem cells CURRENT OPINION IN BIOTECHNOLOGY, 20, 5, 516-521 CURRENT OPINION IN BIOTECHNOLOGY, 20, 5, 516-521 CURRENT OPINION IN BIOTECHNOLOGY, 20, 5, 516-521 2009/10 Refereed English Disclose to all
Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Virus-free induction of pluripotency and subsequent excision of reprogramming factors Virus-free induction of pluripotency and subsequent excision of reprogramming factors Virus-free induction of pluripotency and subsequent excision of reprogramming factors NATURE, 458, 7239, 771-U112 NATURE, 458, 7239, 771-U112 NATURE, 458, 7239, 771-U112 2009/04 Refereed English Research paper(scientific journal) Disclose to all
Knut Woltjen, Iacovos P. Michael, Paria Mohseni, Ridham Desai, Maria Mileikovsky, Riikka Haemaelaeinen, Rebecca Cowling, Wei Wang, Pentao Liu, Marina Gertsenstein, Keisuke Kaji, Hoon-Ki Sung, Andras Nagy Knut Woltjen, Iacovos P. Michael, Paria Mohseni, Ridham Desai, Maria Mileikovsky, Riikka Haemaelaeinen, Rebecca Cowling, Wei Wang, Pentao Liu, Marina Gertsenstein, Keisuke Kaji, Hoon-Ki Sung, Andras Nagy Knut Woltjen, Iacovos P. Michael, Paria Mohseni, Ridham Desai, Maria Mileikovsky, Riikka Haemaelaeinen, Rebecca Cowling, Wei Wang, Pentao Liu, Marina Gertsenstein, Keisuke Kaji, Hoon-Ki Sung, Andras Nagy piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells NATURE, 458, 7239, 766-U106 NATURE, 458, 7239, 766-U106 NATURE, 458, 7239, 766-U106 2009/04 Refereed English Research paper(scientific journal) Disclose to all
Knut Woltjen, Kenichi Ito, Teruhisa Tsuzuki, Derrick E. Rancourt Knut Woltjen, Kenichi Ito, Teruhisa Tsuzuki, Derrick E. Rancourt Knut Woltjen, Kenichi Ito, Teruhisa Tsuzuki, Derrick E. Rancourt Orpheus recombination: A comprehensive bacteriophage system for murine targeting vector construction by transplacement Orpheus recombination: A comprehensive bacteriophage system for murine targeting vector construction by transplacement Orpheus recombination: A comprehensive bacteriophage system for murine targeting vector construction by transplacement Methods in Molecular Biology, 435, 79-94 Methods in Molecular Biology, 435, 79-94 Methods in Molecular Biology, 435, 79-94 2008 Refereed English Research paper(scientific journal) Disclose to all
B Thomas, K Woltjen, DE Rancourt B Thomas, K Woltjen, DE Rancourt B Thomas, K Woltjen, DE Rancourt Deep screening of recombination proficient bacteriophage libraries Deep screening of recombination proficient bacteriophage libraries Deep screening of recombination proficient bacteriophage libraries BIOTECHNIQUES, 34, 1, 36-+ BIOTECHNIQUES, 34, 1, 36-+ BIOTECHNIQUES, 34, 1, 36-+ 2003/01 Refereed English Research paper(scientific journal) Disclose to all
C Aoyama, K Woltjen, FC Mansergh, K Ishidate, DE Rancourt C Aoyama, K Woltjen, FC Mansergh, K Ishidate, DE Rancourt C Aoyama, K Woltjen, FC Mansergh, K Ishidate, DE Rancourt Bacteriophage gene targeting vectors generated by transplacement Bacteriophage gene targeting vectors generated by transplacement Bacteriophage gene targeting vectors generated by transplacement BIOTECHNIQUES, 33, 4, 806-+ BIOTECHNIQUES, 33, 4, 806-+ BIOTECHNIQUES, 33, 4, 806-+ 2002/10 Refereed English Research paper(scientific journal) Disclose to all
K. Woltjen, M.W. Unger, D.E. Rancourt Woltjen K, Unger MW, Rancourt DE K. Woltjen, M.W. Unger, D.E. Rancourt Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Methods in molecular biology (Clifton, N.J.), 182, 189-207 Methods in molecular biology (Clifton, N.J.), 182, 189-207 Methods in molecular biology (Clifton, N.J.), 182, 189-207 2002 Refereed English Research paper(scientific journal) Disclose to all
K. Woltjen, G. Bain, D.E. Rancourt K. Woltjen, G. Bain, D.E. Rancourt K. Woltjen, G. Bain, D.E. Rancourt Retro-recombination screening of a mouse embryonic stem cell genomic library. Retro-recombination screening of a mouse embryonic stem cell genomic library. Retro-recombination screening of a mouse embryonic stem cell genomic library. Nucleic acids research, 28, 9, E41 Nucleic acids research, 28, 9, E41 Nucleic acids research, 28, 9, E41 2000 Refereed English Disclose to all

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上田 樹, 入口 翔一, 河合 洋平, 南川 淳隆, 三好 浩之, 寺倉 精太郎, 植村 靖史, ウォルツェン・クヌート, 児玉 裕三, 玉田 耕治, 中面 哲也, 妹尾 浩, 金子 新 上田 樹, 入口 翔一, 河合 洋平, 南川 淳隆, 三好 浩之, 寺倉 精太郎, 植村 靖史, ウォルツェン・クヌート, 児玉 裕三, 玉田 耕治, 中面 哲也, 妹尾 浩, 金子 新 上田 樹, 入口 翔一, 河合 洋平, 南川 淳隆, 三好 浩之, 寺倉 精太郎, 植村 靖史, ウォルツェン・クヌート, 児玉 裕三, 玉田 耕治, 中面 哲也, 妹尾 浩, 金子 新 GPC3を標的としたiPS細胞由来CAR-T療法 GPC3を標的としたiPS細胞由来CAR-T療法 GPC3を標的としたiPS細胞由来CAR-T療法 日本癌学会総会記事, 76回, P-1251 日本癌学会総会記事, 76回, P-1251 日本癌学会総会記事, 76回, P-1251 2017/09 English Disclose to all
金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 日本癌学会総会記事, 75回, J-2044 日本癌学会総会記事, 75回, J-2044 日本癌学会総会記事, 75回, J-2044 2016/10 English Disclose to all
金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 変異型IDH1は遺伝子特異的なヒストン修飾を介して、間葉系幹細胞から軟骨及び骨への分化を脱制御する 日本癌学会総会記事, 75回, J-2044 日本癌学会総会記事, 75回, J-2044 日本癌学会総会記事, 75回, J-2044 2016/10 English Disclose to all
金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 金 永輝, Elalaf Hassan, 渡辺 真, 玉置 さくら, 日根野 翔, 松永 一仁, Woltjen Knut, 岡本 健, 松田 秀一, 戸口田 淳也 変異型IDH1は骨・軟骨関連遺伝子のヒストンを遺伝子特異的に修飾し、間葉系幹細胞の分化能を脱制御する 変異型IDH1は骨・軟骨関連遺伝子のヒストンを遺伝子特異的に修飾し、間葉系幹細胞の分化能を脱制御する 変異型IDH1は骨・軟骨関連遺伝子のヒストンを遺伝子特異的に修飾し、間葉系幹細胞の分化能を脱制御する 日本癌学会総会記事, 74回, J-1287 日本癌学会総会記事, 74回, J-1287 日本癌学会総会記事, 74回, J-1287 2015/10 English Disclose to all
Hongmei Lisa Li, Naoko Fujimoto, Noriko Sasakawa, Saya Shirai, Takashi Yamamoto, Knut Woltjen, Akira Watanabe, Hidetoshi Sakurai, Shinya Yamanaka, Akitsu Hotta Hongmei Lisa Li, Naoko Fujimoto, Noriko Sasakawa, Saya Shirai, Takashi Yamamoto, Knut Woltjen, Akira Watanabe, Hidetoshi Sakurai, Shinya Yamanaka, Akitsu Hotta Hongmei Lisa Li, Naoko Fujimoto, Noriko Sasakawa, Saya Shirai, Takashi Yamamoto, Knut Woltjen, Akira Watanabe, Hidetoshi Sakurai, Shinya Yamanaka, Akitsu Hotta Engineered Nuclease Mediated Genetic Correction in iPSCs Derived From Duchenne Muscular Dystrophy Patient Engineered Nuclease Mediated Genetic Correction in iPSCs Derived From Duchenne Muscular Dystrophy Patient Engineered Nuclease Mediated Genetic Correction in iPSCs Derived From Duchenne Muscular Dystrophy Patient MOLECULAR THERAPY, 22, S124-S124 MOLECULAR THERAPY, 22, S124-S124 MOLECULAR THERAPY, 22, S124-S124 2014/05 English Research paper, summary (international conference) Disclose to all
李 紅梅, Woltjen Knut, 高橋 和利, 山中 伸弥, 堀田 秋津 李 紅梅, Woltjen Knut, 高橋 和利, 山中 伸弥, 堀田 秋津 李 紅梅, Woltjen Knut, 高橋 和利, 山中 伸弥, 堀田 秋津 【ゲノム編集革命:遺伝子改変はZFN・TALEN・CRISPR/Cas三強時代へ】 TALENを用いたヒトiPS細胞におけるゲノム編集 【ゲノム編集革命:遺伝子改変はZFN・TALEN・CRISPR/Cas三強時代へ】TALENを用いたヒトiPS細胞におけるゲノム編集 【ゲノム編集革命:遺伝子改変はZFN・TALEN・CRISPR/Cas三強時代へ】 TALENを用いたヒトiPS細胞におけるゲノム編集 細胞工学, 32, 5, 526-531 細胞工学, 32, 5, 526-531 細胞工学, 32, 5, 526-531 2013/04 Japanese Disclose to all
Hayakawa K, Fukuta M, TamaiS, Kato T, Ikeya M, Otsuka T, Woltjen K, Toguchida J Hayakawa K, Fukuta M, TamaiS, Kato T, Ikeya M, Otsuka T, Woltjen K, Toguchida J Hayakawa K, Fukuta M, TamaiS, Kato T, Ikeya M, Otsuka T, Woltjen K, Toguchida J Application of iPS cell technology \nfor the analysis of origin-unknown sarcoma characterized by a specific fusion gene. Application of iPS cell technology \nfor the analysis of origin-unknown sarcoma characterized by a specific fusion gene. Application of iPS cell technology \nfor the analysis of origin-unknown sarcoma characterized by a specific fusion gene. 第17 回CTOS (2012.11.16.Prague) 第17 回CTOS (2012.11.16.Prague) 第17 回CTOS (2012.11.16.Prague) 2012/11/16 Refereed English Disclose to all
Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Kristina Nagy, Hoon-Ki Sung, Puzheng Zhang, Simon Laflamme, Patrick Vincent, Siamak Agha-Mohammadi, Knut Woltjen, Claudio Monetti, Iacovos Prodromos Michael, Lawrence Charles Smith, Andras Nagy Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (vol 7, pg 693, 2011) Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (vol 7, pg 693, 2011) Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (vol 7, pg 693, 2011) STEM CELL REVIEWS AND REPORTS, 8, 2, 546-546 STEM CELL REVIEWS AND REPORTS, 8, 2, 546-546 STEM CELL REVIEWS AND REPORTS, 8, 2, 546-546 2012/06 English Other Disclose to all
庄子栄美, 櫻井英俊, 中畑龍俊, 田中章仁, ウォルツェンクヌート, 藤井宣晴, 平家敏男, 真鍋康子, 瀬原-藤沢淳子 庄子栄美, 櫻井英俊, 中畑龍俊, 田中章仁, ウォルツェンクヌート, 藤井宣晴, 平家敏男, 真鍋康子, 瀬原-藤沢淳子 デュシェンヌ型筋ジストロフィー患者由来iPS 細胞を用いての病態再現 デュシェンヌ型筋ジストロフィー患者由来iPS 細胞を用いての病態再現 第35 回日本分子生物学会年会(2012.12.12.福岡) 第35 回日本分子生物学会年会(2012.12.12.福岡) 2012 Refereed Japanese Disclose to all
近藤潤一, 田中章仁, WOLTJEN Knut, 沖田圭介, 櫻井英俊 近藤潤一, 田中章仁, WOLTJEN Knut, 沖田圭介, 櫻井英俊 近藤潤一, 田中章仁, WOLTJEN Knut, 沖田圭介, 櫻井英俊 MYF5遺伝子発現制御によるヒトiPS細胞の骨格筋分化誘導の検討 MYF5遺伝子発現制御によるヒトiPS細胞の骨格筋分化誘導の検討 MYF5遺伝子発現制御によるヒトiPS細胞の骨格筋分化誘導の検討 日本分子生物学会年会プログラム・要旨集(Web), 35th, 3P-0561 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 35th, 3P-0561 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 35th, 3P-0561 (WEB ONLY) 2012 Japanese Disclose to all
Fukuta M, Hayakawa K, Tamaki S, Sato S, Ikeya M, Otsuka Y, Woltjen K, Toguchida J Fukuta M, Hayakawa K, Tamaki S, Sato S, Ikeya M, Otsuka Y, Woltjen K, Toguchida J Fukuta M, Hayakawa K, Tamaki S, Sato S, Ikeya M, Otsuka Y, Woltjen K, Toguchida J Establishment and functional \nanalysis of iPS cells with drug-inducible SYT-SSX fusion gene. Establishment and functional \nanalysis of iPS cells with drug-inducible SYT-SSX fusion gene. Establishment and functional \nanalysis of iPS cells with drug-inducible SYT-SSX fusion gene. 第10 回ISSCR(2012.6.14.横浜) 第10 回ISSCR(2012.6.14.横浜) 第10 回ISSCR(2012.6.14.横浜) 2012 Refereed English Disclose to all
福田誠, 早川和男, 玉置さくら, 沖田圭介, 池谷真, Knut Woltjen, 大塚隆信, 戸口田淳也 福田誠, 早川和男, 玉置さくら, 沖田圭介, 池谷真, Knut Woltjen, 大塚隆信, 戸口田淳也 PS 細胞を用いた肉腫研究:滑膜肉腫の起源細胞の解明をめざして PS 細胞を用いた肉腫研究:滑膜肉腫の起源細胞の解明をめざして 第27 回日本整形外科学会基礎学術集会(2012.10.26. 名古屋) 第27 回日本整形外科学会基礎学術集会(2012.10.26. 名古屋) 2012 Refereed Japanese Disclose to all
早川和男, 福田誠, 玉置さくら, 佐藤信吾, 池谷真, 大塚隆信, Knut Woltjen, 戸口田淳也 早川和男, 福田誠, 玉置さくら, 佐藤信吾, 池谷真, 大塚隆信, Knut Woltjen, 戸口田淳也 薬剤誘導型発現ベクターを用いたSYT-SSX 融合遺伝子導入iPS 細胞の樹立 薬剤誘導型発現ベクターを用いたSYT-SSX 融合遺伝子導入iPS 細胞の樹立 第45 回日本整形外科学会骨軟部腫瘍学術 集会(2012.7.15.東京) 第45 回日本整形外科学会骨軟部腫瘍学術 集会(2012.7.15.東京) 2012 Refereed Japanese Disclose to all
Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Keisuke Kaji, Katherine Norrby, Agnieszka Paca, Maria Mileikovsky, Paria Mohseni, Knut Woltjen Virus-free induction of pluripotency and subsequentexcision of reprogramming factors Virus-free induction of pluripotency and subsequentexcision of reprogramming factors Virus-free induction of pluripotency and subsequentexcision of reprogramming factors MECHANISMS OF DEVELOPMENT, 126, S277-S277 MECHANISMS OF DEVELOPMENT, 126, S277-S277 MECHANISMS OF DEVELOPMENT, 126, S277-S277 2009/08 English Research paper, summary (international conference) Disclose to all

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Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining[Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019/02/21 English Oral presentation(invited, special) Disclose to all
The history and potential of iPSC research[Invited] The history and potential of iPSC research [Invited] The history and potential of iPSC research [Invited] AAAS 2019 Annual Meeting AAAS 2019 Annual Meeting AAAS 2019 Annual Meeting 2019/02/15 English Oral presentation(invited, special) Disclose to all
医療応用に向けたヒトiPS細胞でのゲノム編集[Invited] 医療応用に向けたヒトiPS細胞でのゲノム編集 [Invited] OPERA「ゲノム編集」産学共創コンソーシアム・公開シンポジウム、卓越大学院キックオフシンポジウム OPERA「ゲノム編集」産学共創コンソーシアム・公開シンポジウム、卓越大学院キックオフシンポジウム 2018/12/10 English Symposium workshop panel(nominated) Disclose to all
Japan’s experience in regenerative medicine and superdonor cells[Invited] Japan’s experience in regenerative medicine and superdonor cells [Invited] Japan’s experience in regenerative medicine and superdonor cells [Invited] NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ 2018/12/07 English Symposium workshop panel(nominated) Disclose to all
Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining[Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Concordia University Seminar Concordia University Seminar Concordia University Seminar 2018/12/06 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] The 41st Annual Meeting of the Molecular Biology Society of Japan 第41回日本分子生物学会年会 The 41st Annual Meeting of the Molecular Biology Society of Japan 2018/11/28 English Oral presentation(invited, special) Disclose to all
Genome editing in stem cells to study the mechanisms of reprogramming and human disease[Invited] Genome editing in stem cells to study the mechanisms of reprogramming and human disease [Invited] Genome editing in stem cells to study the mechanisms of reprogramming and human disease [Invited] Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) 2018/09/14 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining EMBO at BASEL LIFE 2018 EMBO at BASEL LIFE 2018 EMBO at BASEL LIFE 2018 2018/09/13 English Oral presentation(invited, special) Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] IREM seminar( University of Zurich) IREM seminar( University of Zurich) IREM seminar( University of Zurich) 2018/09/12 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Genome Engineering: The CRISPR-Cas Revolution Genome Engineering: The CRISPR-Cas Revolution Genome Engineering: The CRISPR-Cas Revolution 2018/08/25 English Oral presentation(invited, special) Disclose to all
Employing microhomology-mediated end joining for the creation and correction of human disease alleles[Invited] Employing microhomology-mediated end joining for the creation and correction of human disease alleles [Invited] Employing microhomology-mediated end joining for the creation and correction of human disease alleles [Invited] Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) 2018/08/22 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ)[Invited] Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] 3rd Annual Meeting of The Japanese Society for Genome Editing 日本ゲノム編集学会第3回大会 3rd Annual Meeting of The Japanese Society for Genome Editing 2018/06/19 English Oral presentation(invited, special) Disclose to all
GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA[Invited] GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA [Invited] GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA [Invited] "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) 2018/03/29 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
The development of induced pluripotent stem cells and emerging tools for genome editing[Invited] The development of induced pluripotent stem cells and emerging tools for genome editing [Invited] The development of induced pluripotent stem cells and emerging tools for genome editing [Invited] "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) 2018/03/28 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ)[Invited] Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] The 9th Takeda Science Foundation Symposium on PharmaSciences 第9回武田科学振興財団薬科学シンポジウム The 9th Takeda Science Foundation Symposium on PharmaSciences 2018/02/07 English Symposium workshop panel(nominated) Disclose to all
Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells[Invited] Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells [Invited] Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells [Invited] Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) 2017/09/14 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Genetic engineering of iPS cells for modelling genodermatoses[Invited] Genetic engineering of iPS cells for modelling genodermatoses [Invited] Genetic engineering of iPS cells for modelling genodermatoses [Invited] The 38th Annual Meeting of the Japanese Society of Inflammation and Regeneration 第38回日本炎症・再生医学会 The 38th Annual Meeting of the Japanese Society of Inflammation and Regeneration 2017/07/19 English Oral presentation(invited, special) Disclose to all
Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs[Invited] Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs [Invited] Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs [Invited] 2nd Annual Meeting of The Japanese Society for Genome Editing 日本ゲノム編集学会第2回大会 2nd Annual Meeting of The Japanese Society for Genome Editing 2017/06/29 English Oral presentation(invited, special) Disclose to all
Genetic engineering of pluripotent stem cells by CRISPR/Cas[Invited] Genetic engineering of pluripotent stem cells by CRISPR/Cas [Invited] Genetic engineering of pluripotent stem cells by CRISPR/Cas [Invited] 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 2017/06/05 English Symposium workshop panel(nominated) Disclose to all
Engineering iPS cell models of human disease[Invited] Engineering iPS cell models of human disease [Invited] Engineering iPS cell models of human disease [Invited] The 75th Annual Meeting of the Japanese Cancer Association 第75回日本癌学会学術総会 The 75th Annual Meeting of the Japanese Cancer Association 2016/10/07 English Oral presentation(invited, special) Disclose to all
An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming[Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] Liaison Laboratory Regular Seminar/HIGO Program Cutting-edge Seminar 熊本大学リエゾンラボ研究会/HIGOプログラム最先端研究セミナー Liaison Laboratory Regular Seminar/HIGO Program Cutting-edge Seminar 2016/02/17 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming[Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] 九州大学大学院医学研究院 第35回生命医科学セミナー 九州大学大学院医学研究院 第35回生命医科学セミナー 2016/02/16 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology[Invited] At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology [Invited] At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology [Invited] Conference on Transposition and Genome Engineering 2015 Conference on Transposition and Genome Engineering 2015 Conference on Transposition and Genome Engineering 2015 2015/11/20 English Oral presentation(invited, special) Disclose to all
Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling[Invited] Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling [Invited] Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling [Invited] Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) 2014/11/06 English Oral presentation(invited, special) Disclose to all
From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling[Invited] From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling [Invited] From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling [Invited] The 71st of Stem Cell Biology and Regenerative Medicine Forum The 71th of Stem Cell Biology and Regenerative Medicine Forum The 71st of Stem Cell Biology and Regenerative Medicine Forum 2014/06/30 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Recombinant DNA and Cell Technologies Enabling Human Functional Genomics[Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Tokyo Tech Bio 2013 Tokyo Tech Bio 2013 Tokyo Tech Bio 2013 2014/01/29 English Symposium workshop panel(nominated) Disclose to all
Recombinant DNA and Cell Technologies Enabling Human Functional Genomics[Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) 2013/11/04 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation[Invited] Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation [Invited] Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation [Invited] Transposition and Genome Engineering 2013 Transposition and Genome Engineering 2013 Transposition and Genome Engineering 2013 2013/09 English Oral presentation(invited, special) Disclose to all
Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation[Invited] Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation [Invited] Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation [Invited] 46th Annual Meeting of the Japanese Society of Development Biologists 第46回日本発生生物学会 46th Annual Meeting of the Japanese Society of Development Biologists 2013/05/31 English Oral presentation(invited, special) Disclose to all
Cell Identity Transitions During Induced Reprogramming to Pluripotency[Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] The 7th Annual Meeting of the Japanese Society for Epigenetics 第7回日本エピジェネティクス研究会年会 The 7th Annual Meeting of the Japanese Society for Epigenetics 2013/05 English Oral presentation(invited, special) Disclose to all
Cell Identity Transitions During Induced Reprogramming to Pluripotency[Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] CDB Seminar CDB Seminar CDB Seminar 2013/03/29 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation[Invited] Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation [Invited] Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation [Invited] iCeMS-Stem Cells Australia Joint Symposium iCeMS-Stem Cells Australia Joint Symposium iCeMS-Stem Cells Australia Joint Symposium 2013/02/12 English Symposium workshop panel(nominated) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
Harunobu Kagawa, Tomoko Matsumoto, Shin-Il Kim, Knut Woltjen 香川 晴信, 松本 智子, 金 信一, ウォルツェン クヌート Harunobu Kagawa, Tomoko Matsumoto, Shin-Il Kim, Knut Woltjen iPS細胞を用いた正確な ゲノム編集法(MhAX法) iPS細胞を用いた正確な ゲノム編集法(MhAX法) iPS細胞を用いた正確な ゲノム編集法(MhAX法) 実験医学 実験医学 実験医学 2018/10 Contributor Disclose to all
Title language:
Industrial Property Rights (Patent)
Inventor(s) Inventor(s) (Japanese) Inventor(s) (English) Title Title(Japanese) Title(English) Stage Patent number Date Disclose
Knut Woltjen, Shin-Il Kim, Tomoko Matsumoto ウォルツェン クヌート, 金 信一, 松本 智子 Knut Woltjen, Shin-Il Kim, Tomoko Matsumoto Method for genome editing Method for genome editing Method for genome editing 特許出願 特願PCT/IB2017/054736 2017/08/02 Disclose to all
Title language:
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
若手研究(B) Representative トランスポゾンを利用した一塩基レベル遺伝子ターゲティング 2011-2013
基盤研究(C) Representative 再生医療の実現に向けたHLA発現制御可能ユニバーサルiPS細胞の樹立 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(C) Representative 再生医療の実現に向けたHLA発現制御可能ユニバーサルiPS細胞の樹立 (平成30年度分) 2018/04/01-2019/03/31
基盤研究(C) Representative 再生医療の実現に向けたHLA発現制御可能ユニバーサルiPS細胞の樹立 (2019年度分) 2019/04/01-2020/03/31
External funds: other than those above
System Main person Title(Japanese) Title(English) Period
リプログラミング開始における細胞応答の解析 Immediate Early Events in Reprogramming Leading to Cellular Plasticity 2010-2012
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2013/04-2014/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2014/04-2015/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2015/04-2016/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2016/04-2017/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2017/04-2018/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2018/04-2019/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2019/04-2020/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2020/04-2021/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2021/04-2022/03
Faculty management (title, position)
Title Period
組換えDNA実験安全委員会4号委員 2018/04/01-2020/03/31