林 康紀

最終更新日時: 2019/06/17 18:13:45

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氏名(漢字/フリガナ/アルファベット表記)
林 康紀/ハヤシ ヤスノリ/Hayashi, Yasunori
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学専攻高次脳科学講座システム神経薬理学/教授
学部兼担
部局 所属 講座等 職名
医学部
連絡先住所
種別 住所(日本語) 住所(英語)
職場 京都府京都市左京区吉田近衛町 Yoshidakonoe-cho, Sakyo, Kyoto, Kyoto, Japan
連絡先電話番号
種別 番号
職場 075-753-7531 ext 84393
電子メールアドレス
メールアドレス
yhayashi-tky @ umin.ac.jp
所属学会(国内)
学会名(日本語) 学会名(英語)
日本神経科学学会 Japanese Society fo Neuroscience
日本薬理学会 Japan Society for Pharmacology
日本生理学会 Japan Society for Physiology
所属学会(海外)
学会名(英語) 国名
Society for Neuroscience US
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) MD, PhD 京都大学 Kyoto University
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
京都大学 Kyoto University 大学院医学研究科博士課程生理系専攻 Graduate School of Medicine 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
京都大学 Kyoto University 医学部医学科 Faculty of Medicine 卒業
プロフィール
(日本語)
私たちは日々新しい事を記憶していきます。しかも驚くべき事に、一旦記憶されたことは何十年にもわたって思い出すことが出来ます。このような記憶を脳の中に保持し続けるメカニズムは何でしょうか。私たちは特に、海馬という部分に着目し、研究を進めています。この部位では、一過性の刺激によって長期間シナプス反応が増強する、長期増強(LTP)という現象が知られています。私たちはLTPが記憶の細胞モデルと考え、その分子メカニズムを解明しようとしています。
(英語)
We daily form new memory. Surprisingly, we can still recall old memory even decades later. What is the mechanism that allows us to form, store, and recall memory? We are interested in a brain structure called hippocampus. In this area, a brief but strong stimulation can cause a long-lasting change in synaptic transmission. We consider this phenomena, long-term potentiation or LTP, is a cellular counterpart of learning and memory and focus our effort to elucidating its molecular mechanisms.
個人ホームページ
URL
glutamate.med.kyoto-u.ac.jp/e/
ORCID ID
https://orcid.org/0000-0002-7560-3004
researchmap URL
https://researchmap.jp/2rikenbsi
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Hayashi Y Hayashi Y Hayashi Y Drebrin-Homer Interaction at An Atomic Scale. Drebrin-Homer Interaction at An Atomic Scale. Drebrin-Homer Interaction at An Atomic Scale. Structure (London, England : 1993), 27, 1, 3-5 Structure (London, England : 1993), 27, 1, 3-5 Structure (London, England : 1993), 27, 1, 3-5 2019/01 研究論文(学術雑誌) 公開
Kim K, Suzuki A, Kojima H, Kawamura M, Miya K, Abe M, Yamada I, Furuse T, Wakana S, Sakimura K, Hayashi Y Kim K, Suzuki A, Kojima H, Kawamura M, Miya K, Abe M, Yamada I, Furuse T, Wakana S, Sakimura K, Hayashi Y Kim K, Suzuki A, Kojima H, Kawamura M, Miya K, Abe M, Yamada I, Furuse T, Wakana S, Sakimura K, Hayashi Y Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning. Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning. Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning. Neurobiology of learning and memory Neurobiology of learning and memory Neurobiology of learning and memory 2018/12 公開
Kobayashi T, Islam T, Sato M, Ohkura M, Nakai J, Hayashi Y, Okamoto H Kobayashi T, Islam T, Sato M, Ohkura M, Nakai J, Hayashi Y, Okamoto H Kobayashi T, Islam T, Sato M, Ohkura M, Nakai J, Hayashi Y, Okamoto H Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex Wide and Deep Imaging of Neuronal Activities by a Wearable NeuroImager Reveals Premotor Activity in the Whole Motor Cortex 2018/10 公開
Yurina Kashino, Yutaro Obara, Yosuke Okamoto, Takeo Saneyoshi, Yasunori Hayashi, Kuniaki Ishii Yurina Kashino, Yutaro Obara, Yosuke Okamoto, Takeo Saneyoshi, Yasunori Hayashi, Kuniaki Ishii Yurina Kashino, Yutaro Obara, Yosuke Okamoto, Takeo Saneyoshi, Yasunori Hayashi, Kuniaki Ishii ERK5 Phosphorylates K<sub>v</sub>4.2 and Inhibits Inactivation of the A-Type Current in PC12 Cells ERK5 Phosphorylates K<sub>v</sub>4.2 and Inhibits Inactivation of the A-Type Current in PC12 Cells ERK5 Phosphorylates K<sub>v</sub>4.2 and Inhibits Inactivation of the A-Type Current in PC12 Cells International Journal of Molecular Sciences, 19, 7, 2008 International Journal of Molecular Sciences, 19, 7, 2008 International Journal of Molecular Sciences, 19, 7, 2008 2018/07 公開
Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Grødem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Grødem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Grødem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities. Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities. Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities. Journal of neurochemistry Journal of neurochemistry Journal of neurochemistry 2018/07 公開
Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Groedem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Groedem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Hallin EI, Eriksen MS, Baryshnikov S, Nikolaienko O, Groedem S, Hosokawa T, Hayashi Y, Bramham CR, Kursula P Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities 2018/05 公開
Sato M, Mizuta K, Islam T, Kawano M, Takekawa T, Gomez-Dominguez D, Kim K, Yamakawa H, Ohkura M, Fukai T, Nakai J, Hayashi Y Sato M, Mizuta K, Islam T, Kawano M, Takekawa T, Gomez-Dominguez D, Kim K, Yamakawa H, Ohkura M, Fukai T, Nakai J, Hayashi Y Sato M, Mizuta K, Islam T, Kawano M, Takekawa T, Gomez-Dominguez D, Kim K, Yamakawa H, Ohkura M, Fukai T, Nakai J, Hayashi Y Dynamic embedding of salience coding in hippocampal spatial maps Dynamic embedding of salience coding in hippocampal spatial maps Dynamic embedding of salience coding in hippocampal spatial maps 2018/02 公開
Takekawa T, Asai H, Ohkawa N, Nomoto M, Okubo-Suzuki R, Ghandour K, Sato M, Hayashi Y, Inokuchi K, Fukai T Takekawa T, Asai H, Ohkawa N, Nomoto M, Okubo-Suzuki R, Ghandour K, Sato M, Hayashi Y, Inokuchi K, Fukai T Takekawa T, Asai H, Ohkawa N, Nomoto M, Okubo-Suzuki R, Ghandour K, Sato M, Hayashi Y, Inokuchi K, Fukai T Automatic sorting system for large calcium imaging data Automatic sorting system for large calcium imaging data Automatic sorting system for large calcium imaging data 2017/11 公開
Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Hasan MT Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Hasan MT Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Hasan MT Building Bridges through Science. Building Bridges through Science. Building Bridges through Science. Neuron, 96, 4, 730-735 Neuron, 96, 4, 730-735 Neuron, 96, 4, 730-735 2017/11 公開
Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality. Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality. Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality. eNeuro eNeuro eNeuro 2017 公開
Photomarking Relocalization Technique for Correlated Two-Photon and Electron Microcopy Imaging of Single Stimulated Synapses. Photomarking Relocalization Technique for Correlated Two-Photon and Electron Microcopy Imaging of Single Stimulated Synapses. Photomarking Relocalization Technique for Correlated Two-Photon and Electron Microcopy Imaging of Single Stimulated Synapses. Methods in molecular biology (Clifton, N.J.) Methods in molecular biology (Clifton, N.J.) Methods in molecular biology (Clifton, N.J.) 2017 公開
Interplay of enzymatic and structural functions of CaMKII in long-term potentiation. Interplay of enzymatic and structural functions of CaMKII in long-term potentiation. Interplay of enzymatic and structural functions of CaMKII in long-term potentiation. Journal of neurochemistry Journal of neurochemistry Journal of neurochemistry 2016/12 公開
In vivo two-photon imaging of striatal neuronal circuits in mice. In vivo two-photon imaging of striatal neuronal circuits in mice. In vivo two-photon imaging of striatal neuronal circuits in mice. Neurobiology of learning and memory Neurobiology of learning and memory Neurobiology of learning and memory 2016/07 公開
A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. Neuron Neuron Neuron 2015/10 公開
A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII. Neuron Neuron Neuron 2015/08 公開
A Top-Down Cortical Circuit for Accurate Sensory Perception. A Top-Down Cortical Circuit for Accurate Sensory Perception. A Top-Down Cortical Circuit for Accurate Sensory Perception. Neuron Neuron Neuron 2015/06 公開
Stoichiometry and phosphoisotypes of hippocampal AMPA-type glutamate receptor phosphorylation. Stoichiometry and phosphoisotypes of hippocampal AMPA-type glutamate receptor phosphorylation. Stoichiometry and phosphoisotypes of hippocampal AMPA-type glutamate receptor phosphorylation. Neuron Neuron Neuron 2015/01 公開
A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia. A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia. A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia. PloS one PloS one PloS one 2015 公開
Generation and Imaging of Transgenic Mice that Express G-CaMP7 under a Tetracycline Response Element. Generation and Imaging of Transgenic Mice that Express G-CaMP7 under a Tetracycline Response Element. Generation and Imaging of Transgenic Mice that Express G-CaMP7 under a Tetracycline Response Element. PloS one PloS one PloS one 2015 公開
Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice. Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice. Inhibiting the Activity of CA1 Hippocampal Neurons Prevents the Recall of Contextual Fear Memory in Inducible ArchT Transgenic Mice. PloS one PloS one PloS one 2015 公開
CaMKII: the Swiss army knife of synaptic plasticity. CaMKII: the Swiss army knife of synaptic plasticity. CaMKII: the Swiss army knife of synaptic plasticity. The Journal of physiology The Journal of physiology The Journal of physiology 2014/11 公開
Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain. Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain. Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain. Glia Glia Glia 2014/09 公開
Synapse reorganization-a new partnership revealed. Synapse reorganization-a new partnership revealed. Synapse reorganization-a new partnership revealed. The EMBO Journal The EMBO Journal The EMBO Journal 2014/06 公開
Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Neuron Neuron Neuron 2014/04 公開
PIP₃ regulates spinule formation in dendritic spines during structural long-term potentiation. PIP₃ regulates spinule formation in dendritic spines during structural long-term potentiation. PIP₃ regulates spinule formation in dendritic spines during structural long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience The Journal of neuroscience : the official journal of the Society for Neuroscience The Journal of neuroscience : the official journal of the Society for Neuroscience 2013/07 公開
Application of FRET probes in the analysis of neuronal plasticity. Application of FRET probes in the analysis of neuronal plasticity. Application of FRET probes in the analysis of neuronal plasticity. Frontiers in neural circuits Frontiers in neural circuits Frontiers in neural circuits 2013 公開
Wang D.O, Matsuno H, Ikeda S, Nakamura A, Yanagisawa H, Hayashi Y, Okamoto A. Wang D.O, Matsuno H, Ikeda S, Nakamura A, Yanagisawa H, Hayashi Y, Okamoto A. Wang D.O, Matsuno H, Ikeda S, Nakamura A, Yanagisawa H, Hayashi Y, Okamoto A. A quick and simple FISH protocol with hybridization-sensitive fluorescent linear oligodeoxynucleotide probes A quick and simple FISH protocol with hybridization-sensitive fluorescent linear oligodeoxynucleotide probes A quick and simple FISH protocol with hybridization-sensitive fluorescent linear oligodeoxynucleotide probes RNA, 18, 1, 166-175 RNA, 18, 1, 166-175 RNA, 18, 1, 166-175 2012 公開
Sakaguchi M, Hayashi Y. Sakaguchi M, Hayashi Y. Sakaguchi M, Hayashi Y. Catching the engram: Strategies to examine the memory trace Catching the engram: Strategies to examine the memory trace Catching the engram: Strategies to examine the memory trace Molecular Brain, 5, 1 Molecular Brain, 5, 1 Molecular Brain, 5, 1 2012 公開
Hayashi Y, Okamoto K.-I, Bosch M, Futai K. Hayashi Y, Okamoto K.-I, Bosch M, Futai K. Hayashi Y, Okamoto K.-I, Bosch M, Futai K. Roles of neuronal activity-induced gene products in hebbian and homeostatic synaptic plasticity, tagging, and capture Roles of neuronal activity-induced gene products in hebbian and homeostatic synaptic plasticity, tagging, and capture Roles of neuronal activity-induced gene products in hebbian and homeostatic synaptic plasticity, tagging, and capture Advances in Experimental Medicine and Biology, 970, 335-354 Advances in Experimental Medicine and Biology, 970, 335-354 Advances in Experimental Medicine and Biology, 970, 335-354 2012 公開
Bosch M, Hayashi Y. Bosch M, Hayashi Y. Bosch M, Hayashi Y. Structural plasticity of dendritic spines Structural plasticity of dendritic spines Structural plasticity of dendritic spines Current Opinion in Neurobiology, 22, 3, 383-388 Current Opinion in Neurobiology, 22, 3, 383-388 Current Opinion in Neurobiology, 22, 3, 383-388 2012 公開
Saneyoshi T, Hayashi Y. Saneyoshi T, Hayashi Y. Saneyoshi T, Hayashi Y. The ca 2+ and rho gtpase signaling pathways underlying activity-dependent actin remodeling at dendritic spines The ca 2+ and rho gtpase signaling pathways underlying activity-dependent actin remodeling at dendritic spines The ca 2+ and rho gtpase signaling pathways underlying activity-dependent actin remodeling at dendritic spines Cytoskeleton, 69, 8, 545-554 Cytoskeleton, 69, 8, 545-554 Cytoskeleton, 69, 8, 545-554 2012 公開
Tomohisa Hosokawa, Yasunori Hayashi Tomohisa Hosokawa, Yasunori Hayashi Tomohisa Hosokawa, Yasunori Hayashi A quantitative analysis of AMPA receptor GluR1 phospho-isotypes A quantitative analysis of AMPA receptor GluR1 phospho-isotypes A quantitative analysis of AMPA receptor GluR1 phospho-isotypes Neuroscience Research, 71 Neuroscience Research, 71 Neuroscience Research, 71 2011 公開
Mower A.F, Kwok S, Yu H, Majewska A.K, Okamoto K.-I, Hayashi Y, Sur M. Mower A.F, Kwok S, Yu H, Majewska A.K, Okamoto K.-I, Hayashi Y, Sur M. Mower A.F, Kwok S, Yu H, Majewska A.K, Okamoto K.-I, Hayashi Y, Sur M. Experience-dependent regulation of CaMKII activity within single visual cortex synapses in vivo Experience-dependent regulation of CaMKII activity within single visual cortex synapses in vivo Experience-dependent regulation of CaMKII activity within single visual cortex synapses in vivo Proceedings of the National Academy of Sciences of the United States of America, 108, 52, 21241-21246 Proceedings of the National Academy of Sciences of the United States of America, 108, 52, 21241-21246 Proceedings of the National Academy of Sciences of the United States of America, 108, 52, 21241-21246 2011 公開
Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Esteban JA, Osten P, Seidenman K Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Esteban JA, Osten P, Seidenman K Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Esteban JA, Osten P, Seidenman K Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harbor protocols, 2010, 4, pdb.prot5406 Cold Spring Harbor protocols, 2010, 4, pdb.prot5406 Cold Spring Harbor protocols, 2010, 4, pdb.prot5406 2010/04 公開
Karam Kim, Kenichi Okamoto, Kaoru Matsuura, Yasunori Hayashi Karam Kim, Kenichi Okamoto, Kaoru Matsuura, Yasunori Hayashi Karam Kim, Kenichi Okamoto, Kaoru Matsuura, Yasunori Hayashi Structural plasticity mediated by CaMKII Structural plasticity mediated by CaMKII Structural plasticity mediated by CaMKII Neuroscience Research, 68 Neuroscience Research, 68 Neuroscience Research, 68 2010 公開
Okamoto K, Bosch M, Hayashi Y Okamoto K, Bosch M, Hayashi Y Okamoto K, Bosch M, Hayashi Y The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag? The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag? The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag? Physiology (Bethesda, Md.), 24, 357-366 Physiology (Bethesda, Md.), 24, 357-366 Physiology (Bethesda, Md.), 24, 357-366 2009/12 公開
Hayashi Y Hayashi Y Hayashi Y Long-term potentiation: two pathways meet at neurogranin. Long-term potentiation: two pathways meet at neurogranin. Long-term potentiation: two pathways meet at neurogranin. The EMBO journal, 28, 19, 2859-2860 The EMBO journal, 28, 19, 2859-2860 The EMBO journal, 28, 19, 2859-2860 2009/10 公開
Kishi K, van Vugt MA, Okamoto K, Hayashi Y, Yaffe MB Kishi K, van Vugt MA, Okamoto K, Hayashi Y, Yaffe MB Kishi K, van Vugt MA, Okamoto K, Hayashi Y, Yaffe MB Functional dynamics of Polo-like kinase 1 at the centrosome. Functional dynamics of Polo-like kinase 1 at the centrosome. Functional dynamics of Polo-like kinase 1 at the centrosome. Molecular and cellular biology, 29, 11, 3134-3150 Molecular and cellular biology, 29, 11, 3134-3150 Molecular and cellular biology, 29, 11, 3134-3150 2009/06 公開
Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu RM, Li H, Sala C, Hayashi Y Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu RM, Li H, Sala C, Hayashi Y Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu RM, Li H, Sala C, Hayashi Y The postsynaptic density proteins Homer and Shank form a polymeric network structure. The postsynaptic density proteins Homer and Shank form a polymeric network structure. The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell, 137, 1, 159-171 Cell, 137, 1, 159-171 Cell, 137, 1, 159-171 2009/04 公開
Okamoto K, Bosch M, Hayashi Y. Okamoto K, Bosch M, Hayashi Y. Okamoto K, Bosch M, Hayashi Y. The roles of CaMKII and F-Actin in the structural plasticity of dendritic Spines: A potential molecular identity of a synaptic tag? The roles of CaMKII and F-Actin in the structural plasticity of dendritic Spines: A potential molecular identity of a synaptic tag? The roles of CaMKII and F-Actin in the structural plasticity of dendritic Spines: A potential molecular identity of a synaptic tag? Physiology, 24, 6, 357-366 Physiology, 24, 6, 357-366 Physiology, 24, 6, 357-366 2009 公開
Poo MM, Sander L, Fivaz M, Hayashi Y Poo MM, Sander L, Fivaz M, Hayashi Y Poo MM, Sander L, Fivaz M, Hayashi Y Asian promise: the state and future of collaborations in neuroscience. Asian promise: the state and future of collaborations in neuroscience. Asian promise: the state and future of collaborations in neuroscience. Nature reviews. Neuroscience, 9, 11, 881-884 Nature reviews. Neuroscience, 9, 11, 881-884 Nature reviews. Neuroscience, 9, 11, 881-884 2008/11 公開
Kwok S, Lee C, Sánchez SA, Hazlett TL, Gratton E, Hayashi Y Kwok S, Lee C, Sánchez SA, Hazlett TL, Gratton E, Hayashi Y Kwok S, Lee C, Sánchez SA, Hazlett TL, Gratton E, Hayashi Y Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochemical and biophysical research communications, 369, 2, 519-525 Biochemical and biophysical research communications, 369, 2, 519-525 Biochemical and biophysical research communications, 369, 2, 519-525 2008/05 公開
Futai K, Jong Kim M, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y. Futai K, Jong Kim M, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y. Futai K, Jong Kim M, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y. Corrigendum: Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin (Nature Neuroscience (2007) 10 (186-195)) Corrigendum: Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin (Nature Neuroscience (2007) 10 (186-195)) Corrigendum: Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin (Nature Neuroscience (2007) 10 (186-195)) Nature Neuroscience, 11, 2 Nature Neuroscience, 11, 2 Nature Neuroscience, 11, 2 2008 公開
Kwok S, Lee C, Sánchez S.A, Hazlett T.L, Gratton E, Hayashi Y. Kwok S, Lee C, Sánchez S.A, Hazlett T.L, Gratton E, Hayashi Y. Kwok S, Lee C, Sánchez S.A, Hazlett T.L, Gratton E, Hayashi Y. Erratum to "Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity" [Biochem. Biophys. Res. Commun. 369 (2008) 519-525] (DOI:10.1016/j.bbrc.2008.02.070) Erratum to "Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity" [Biochem. Biophys. Res. Commun. 369 (2008) 519-525] (DOI:10.1016/j.bbrc.2008.02.070) Erratum to "Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity" [Biochem. Biophys. Res. Commun. 369 (2008) 519-525] (DOI:10.1016/j.bbrc.2008.02.070) Biochemical and Biophysical Research Communications, 373, 1 Biochemical and Biophysical Research Communications, 373, 1 Biochemical and Biophysical Research Communications, 373, 1 2008 公開
Niemann S, Landers J.E, Churchill M.J, Hosler B, Sapp P, Speed W.C, Lahn B.T, Kidd K.K, Brown Jr. R.H, Hayashi Y. Niemann S, Landers J.E, Churchill M.J, Hosler B, Sapp P, Speed W.C, Lahn B.T, Kidd K.K, Brown Jr. R.H, Hayashi Y. Niemann S, Landers J.E, Churchill M.J, Hosler B, Sapp P, Speed W.C, Lahn B.T, Kidd K.K, Brown Jr. R.H, Hayashi Y. Motoneuron-specific NR3B gene: no association with ALS and evidence for a common null allele. Motoneuron-specific NR3B gene: no association with ALS and evidence for a common null allele. Motoneuron-specific NR3B gene: no association with ALS and evidence for a common null allele. Neurology, 70, 9, 666-676 Neurology, 70, 9, 666-676 Neurology, 70, 9, 666-676 2008 公開
Kim M.J, Futai K, Jo J, Hayashi Y, Cho K, Sheng M. Kim M.J, Futai K, Jo J, Hayashi Y, Cho K, Sheng M. Kim M.J, Futai K, Jo J, Hayashi Y, Cho K, Sheng M. Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95 (DOI:10.1016/j.neuron.2007.09.007) Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95 (DOI:10.1016/j.neuron.2007.09.007) Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95 (DOI:10.1016/j.neuron.2007.09.007) Neuron, 57, 2, 326-327 Neuron, 57, 2, 326-327 Neuron, 57, 2, 326-327 2008 公開
Kim MJ, Futai K, Jo J, Hayashi Y, Cho K, Sheng M Kim MJ, Futai K, Jo J, Hayashi Y, Cho K, Sheng M Kim MJ, Futai K, Jo J, Hayashi Y, Cho K, Sheng M Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Neuron, 56, 3, 488-502 Neuron, 56, 3, 488-502 Neuron, 56, 3, 488-502 2007/11 公開
Niemann S, Kanki H, Fukui Y, Takao K, Fukaya M, Hynynen MN, Churchill MJ, Shefner JM, Bronson RT, Brown RH Jr, Watanabe M, Miyakawa T, Itohara S, Hayashi Y Niemann S, Kanki H, Fukui Y, Takao K, Fukaya M, Hynynen MN, Churchill MJ, Shefner JM, Bronson RT, Brown RH Jr, Watanabe M, Miyakawa T, Itohara S, Hayashi Y Niemann S, Kanki H, Fukui Y, Takao K, Fukaya M, Hynynen MN, Churchill MJ, Shefner JM, Bronson RT, Brown RH Jr, Watanabe M, Miyakawa T, Itohara S, Hayashi Y Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. The European journal of neuroscience, 26, 6, 1407-1420 The European journal of neuroscience, 26, 6, 1407-1420 The European journal of neuroscience, 26, 6, 1407-1420 2007/09 公開
Okamoto K, Narayanan R, Lee SH, Murata K, Hayashi Y Okamoto K, Narayanan R, Lee SH, Murata K, Hayashi Y Okamoto K, Narayanan R, Lee SH, Murata K, Hayashi Y The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6418-6423 Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6418-6423 Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6418-6423 2007/04 公開
Futai K, Kim MJ, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y Futai K, Kim MJ, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y Futai K, Kim MJ, Hashikawa T, Scheiffele P, Sheng M, Hayashi Y Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nature neuroscience, 10, 2, 186-195 Nature neuroscience, 10, 2, 186-195 Nature neuroscience, 10, 2, 186-195 2007/02 公開
Hayashi MK, Ames HM, Hayashi Y Hayashi MK, Ames HM, Hayashi Y Hayashi MK, Ames HM, Hayashi Y Tetrameric hub structure of postsynaptic scaffolding protein homer. Tetrameric hub structure of postsynaptic scaffolding protein homer. Tetrameric hub structure of postsynaptic scaffolding protein homer. The Journal of neuroscience : the official journal of the Society for Neuroscience, 26, 33, 8492-8501 The Journal of neuroscience : the official journal of the Society for Neuroscience, 26, 33, 8492-8501 The Journal of neuroscience : the official journal of the Society for Neuroscience, 26, 33, 8492-8501 2006/08 公開
Okamoto K, Hayashi Y Okamoto K, Hayashi Y Okamoto K, Hayashi Y Visualization of F-actin and G-actin equilibrium using fluorescence resonance energy transfer (FRET) in cultured cells and neurons in slices. Visualization of F-actin and G-actin equilibrium using fluorescence resonance energy transfer (FRET) in cultured cells and neurons in slices. Visualization of F-actin and G-actin equilibrium using fluorescence resonance energy transfer (FRET) in cultured cells and neurons in slices. Nature protocols, 1, 2, 911-919 Nature protocols, 1, 2, 911-919 Nature protocols, 1, 2, 911-919 2006 公開
Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). Journal of the American Chemical Society, 127, 48, 16812-16823 Journal of the American Chemical Society, 127, 48, 16812-16823 Journal of the American Chemical Society, 127, 48, 16812-16823 2005/12 公開
Hayashi Y, Majewska AK Hayashi Y, Majewska AK Hayashi Y, Majewska AK Dendritic spine geometry: functional implication and regulation. Dendritic spine geometry: functional implication and regulation. Dendritic spine geometry: functional implication and regulation. Neuron, 46, 4, 529-532 Neuron, 46, 4, 529-532 Neuron, 46, 4, 529-532 2005/05 公開
Howarth M, Takao K, Hayashi Y, Ting AY Howarth M, Takao K, Hayashi Y, Ting AY Howarth M, Takao K, Hayashi Y, Ting AY Targeting quantum dots to surface proteins in living cells with biotin ligase. Targeting quantum dots to surface proteins in living cells with biotin ligase. Targeting quantum dots to surface proteins in living cells with biotin ligase. Proceedings of the National Academy of Sciences of the United States of America, 102, 21, 7583-7588 Proceedings of the National Academy of Sciences of the United States of America, 102, 21, 7583-7588 Proceedings of the National Academy of Sciences of the United States of America, 102, 21, 7583-7588 2005/05 公開
Fukaya M, Hayashi Y, Watanabe M Fukaya M, Hayashi Y, Watanabe M Fukaya M, Hayashi Y, Watanabe M NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. The European journal of neuroscience, 21, 5, 1432-1436 The European journal of neuroscience, 21, 5, 1432-1436 The European journal of neuroscience, 21, 5, 1432-1436 2005/03 公開
Takao K, Okamoto K, Nakagawa T, Neve RL, Nagai T, Miyawaki A, Hashikawa T, Kobayashi S, Hayashi Y Takao K, Okamoto K, Nakagawa T, Neve RL, Nagai T, Miyawaki A, Hashikawa T, Kobayashi S, Hayashi Y Takao K, Okamoto K, Nakagawa T, Neve RL, Nagai T, Miyawaki A, Hashikawa T, Kobayashi S, Hayashi Y Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 25, 12, 3107-3112 The Journal of neuroscience : the official journal of the Society for Neuroscience, 25, 12, 3107-3112 The Journal of neuroscience : the official journal of the Society for Neuroscience, 25, 12, 3107-3112 2005/03 公開
Li Z, Okamoto K, Hayashi Y, Sheng M Li Z, Okamoto K, Hayashi Y, Sheng M Li Z, Okamoto K, Hayashi Y, Sheng M The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell, 119, 6, 873-887 Cell, 119, 6, 873-887 Cell, 119, 6, 873-887 2004/12 公開
Nakagawa T, Futai K, Lashuel HA, Lo I, Okamoto K, Walz T, Hayashi Y, Sheng M Nakagawa T, Futai K, Lashuel HA, Lo I, Okamoto K, Walz T, Hayashi Y, Sheng M Nakagawa T, Futai K, Lashuel HA, Lo I, Okamoto K, Walz T, Hayashi Y, Sheng M Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions. Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions. Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions. Neuron, 44, 3, 453-467 Neuron, 44, 3, 453-467 Neuron, 44, 3, 453-467 2004/10 公開
Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorganic chemistry, 43, 21, 6774-6779 Inorganic chemistry, 43, 21, 6774-6779 Inorganic chemistry, 43, 21, 6774-6779 2004/10 公開
Okamoto K, Nagai T, Miyawaki A, Hayashi Y Okamoto K, Nagai T, Miyawaki A, Hayashi Y Okamoto K, Nagai T, Miyawaki A, Hayashi Y Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nature neuroscience, 7, 10, 1104-1112 Nature neuroscience, 7, 10, 1104-1112 Nature neuroscience, 7, 10, 1104-1112 2004/10 公開
Semino CE, Kasahara J, Hayashi Y, Zhang S Semino CE, Kasahara J, Hayashi Y, Zhang S Semino CE, Kasahara J, Hayashi Y, Zhang S Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Tissue engineering, 10, 3-4, 643-655 Tissue engineering, 10, 3-4, 643-655 Tissue engineering, 10, 3-4, 643-655 2004/03 公開
Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons. Developmental biology, 263, 2, 216-230 Developmental biology, 263, 2, 216-230 Developmental biology, 263, 2, 216-230 2003/11 公開
Sala C, Futai K, Yamamoto K, Worley PF, Hayashi Y, Sheng M Sala C, Futai K, Yamamoto K, Worley PF, Hayashi Y, Sheng M Sala C, Futai K, Yamamoto K, Worley PF, Hayashi Y, Sheng M Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a. Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a. Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a. The Journal of neuroscience : the official journal of the Society for Neuroscience, 23, 15, 6327-6337 The Journal of neuroscience : the official journal of the Society for Neuroscience, 23, 15, 6327-6337 The Journal of neuroscience : the official journal of the Society for Neuroscience, 23, 15, 6327-6337 2003/07 公開
Shi S.-H, Hayashi Y, Esteban J.A, Malinow R. Shi S.-H, Hayashi Y, Esteban J.A, Malinow R. Shi S.-H, Hayashi Y, Esteban J.A, Malinow R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons Cell, 105, 3, 331-343 Cell, 105, 3, 331-343 Cell, 105, 3, 331-343 2001 公開
Carlezon Jr. W.A, Haile C.N, Coppersmith R, Hayashi Y, Malinow R, Neve R.L, Nestler E.J. Carlezon Jr. W.A, Haile C.N, Coppersmith R, Hayashi Y, Malinow R, Neve R.L, Nestler E.J. Carlezon Jr. W.A, Haile C.N, Coppersmith R, Hayashi Y, Malinow R, Neve R.L, Nestler E.J. Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20, 5 The Journal of neuroscience : the official journal of the Society for Neuroscience, 20, 5 The Journal of neuroscience : the official journal of the Society for Neuroscience, 20, 5 2000 公開
Hayashi Y, Shi S.-H, Esteban J.A, Piccini A, Poncer J.-C, Malinow R. Hayashi Y, Shi S.-H, Esteban J.A, Piccini A, Poncer J.-C, Malinow R. Hayashi Y, Shi S.-H, Esteban J.A, Piccini A, Poncer J.-C, Malinow R. Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction Science, 287, 5461, 2262-2267 Science, 287, 5461, 2262-2267 Science, 287, 5461, 2262-2267 2000 公開
Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Erratum: Postnatal synaptic potentiation: Delivery of glur4-containing ampa receptors by spontaneous activity (nature neuroscience (2000) 3 (1098-1106)) Erratum: Postnatal synaptic potentiation: Delivery of glur4-containing ampa receptors by spontaneous activity (nature neuroscience (2000) 3 (1098-1106)) Erratum: Postnatal synaptic potentiation: Delivery of glur4-containing ampa receptors by spontaneous activity (nature neuroscience (2000) 3 (1098-1106)) Nature Neuroscience, 3, 12 Nature Neuroscience, 3, 12 Nature Neuroscience, 3, 12 2000 公開
Malinow R, Mainen Z.F, Hayashi Y. Malinow R, Mainen Z.F, Hayashi Y. Malinow R, Mainen Z.F, Hayashi Y. LTP mechanisms: From silence to four-lane traffic LTP mechanisms: From silence to four-lane traffic LTP mechanisms: From silence to four-lane traffic Current Opinion in Neurobiology, 10, 3, 352-357 Current Opinion in Neurobiology, 10, 3, 352-357 Current Opinion in Neurobiology, 10, 3, 352-357 2000 公開
Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Zhu J.J, Esteban J.A, Hayashi Y, Malinow R. Postnatal synaptic potentiation: Delivery of GluR4-containing AMPA receptors by spontaneous activity Postnatal synaptic potentiation: Delivery of GluR4-containing AMPA receptors by spontaneous activity Postnatal synaptic potentiation: Delivery of GluR4-containing AMPA receptors by spontaneous activity Nature Neuroscience, 3, 11, 1098-1106 Nature Neuroscience, 3, 11, 1098-1106 Nature Neuroscience, 3, 11, 1098-1106 2000 公開
Shi S.-H, Hayashi Y, Petralia R.S, Zaman S.H, Wenthold R.J, Svoboda K, Malinow R. Shi S.-H, Hayashi Y, Petralia R.S, Zaman S.H, Wenthold R.J, Svoboda K, Malinow R. Shi S.-H, Hayashi Y, Petralia R.S, Zaman S.H, Wenthold R.J, Svoboda K, Malinow R. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation Science, 284, 5412, 1811-1816 Science, 284, 5412, 1811-1816 Science, 284, 5412, 1811-1816 1999 公開
Mainen Z.F, Maletic-Savatic M, Shi S.H, Hayashi Y, Malinow R, Svoboda K. Mainen Z.F, Maletic-Savatic M, Shi S.H, Hayashi Y, Malinow R, Svoboda K. Mainen Z.F, Maletic-Savatic M, Shi S.H, Hayashi Y, Malinow R, Svoboda K. Two-photon imaging in living brain slices Two-photon imaging in living brain slices Two-photon imaging in living brain slices Methods: A Companion to Methods in Enzymology, 18, 2, 231-239 Methods: A Companion to Methods in Enzymology, 18, 2, 231-239 Methods: A Companion to Methods in Enzymology, 18, 2, 231-239 1999 公開
Hayashi Y, Ishida A, Katagiri H, Mishina M, Fujisawa H, Manabe T, Takahashi T. Hayashi Y, Ishida A, Katagiri H, Mishina M, Fujisawa H, Manabe T, Takahashi T. Hayashi Y, Ishida A, Katagiri H, Mishina M, Fujisawa H, Manabe T, Takahashi T. Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density Molecular Brain Research, 46, 1-2, 338-342 Molecular Brain Research, 46, 1-2, 338-342 Molecular Brain Research, 46, 1-2, 338-342 1997 公開
Hayashi Y, Sekiyama N, Nakanishi S, Jane D.E, Sunter D.C, Birse E.F, Udvarhelyi P.M, Watkins J.C. Hayashi Y, Sekiyama N, Nakanishi S, Jane D.E, Sunter D.C, Birse E.F, Udvarhelyi P.M, Watkins J.C. Hayashi Y, Sekiyama N, Nakanishi S, Jane D.E, Sunter D.C, Birse E.F, Udvarhelyi P.M, Watkins J.C. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes Journal of Neuroscience, 14, 5 II, 3370-3377 Journal of Neuroscience, 14, 5 II, 3370-3377 Journal of Neuroscience, 14, 5 II, 3370-3377 1994 公開
Kaba H, Hayashi Y, Higuchi T, Nakanishi S. Kaba H, Hayashi Y, Higuchi T, Nakanishi S. Kaba H, Hayashi Y, Higuchi T, Nakanishi S. Induction of an olfactory memory by the activation of a metabotropic glutamate receptor Induction of an olfactory memory by the activation of a metabotropic glutamate receptor Induction of an olfactory memory by the activation of a metabotropic glutamate receptor Science, 265, 5169, 262-264 Science, 265, 5169, 262-264 Science, 265, 5169, 262-264 1994 公開
Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, Nakanishi S. Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, Nakanishi S. Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, Nakanishi S. Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction Journal of Biological Chemistry, 269, 2, 1231-1236 Journal of Biological Chemistry, 269, 2, 1231-1236 Journal of Biological Chemistry, 269, 2, 1231-1236 1994 公開
Nakanishi S, Masu M, Bessho Y, Nakajima Y, Hayashi Y, Shigemoto R. Nakanishi S, Masu M, Bessho Y, Nakajima Y, Hayashi Y, Shigemoto R. Nakanishi S, Masu M, Bessho Y, Nakajima Y, Hayashi Y, Shigemoto R. Molecular diversity of glutamate receptors and their physiological functions. Molecular diversity of glutamate receptors and their physiological functions. Molecular diversity of glutamate receptors and their physiological functions. EXS, 71, 71-80 EXS, 71, 71-80 EXS, 71, 71-80 1994 公開
Negishi M, Sugimoto Y, Hayashi Y, Namba T, Honda A, Watabe A, Narumiya S, Ichikawa A. Negishi M, Sugimoto Y, Hayashi Y, Namba T, Honda A, Watabe A, Narumiya S, Ichikawa A. Negishi M, Sugimoto Y, Hayashi Y, Namba T, Honda A, Watabe A, Narumiya S, Ichikawa A. Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding Functional interaction of prostaglandin E receptor EP3 subtype with guanine nucleotide-binding proteins, showing low-affinity ligand binding BBA - Molecular Cell Research, 1175, 3, 343-350 BBA - Molecular Cell Research, 1175, 3, 343-350 BBA - Molecular Cell Research, 1175, 3, 343-350 1993 公開
Hayashi Y, Momiyama A, Takahashi T, Ohishi H, Ogawa-Meguro R, Shigemoto R, Mizuno N, Nakanishi S. Hayashi Y, Momiyama A, Takahashi T, Ohishi H, Ogawa-Meguro R, Shigemoto R, Mizuno N, Nakanishi S. Hayashi Y, Momiyama A, Takahashi T, Ohishi H, Ogawa-Meguro R, Shigemoto R, Mizuno N, Nakanishi S. Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb Nature, 366, 6456, 687-690 Nature, 366, 6456, 687-690 Nature, 366, 6456, 687-690 1993 公開
Sugimoto Y, Negishi M, Hayashi Y, Namba T, Honda A, Watabe A, Hirata M, Narumiya S, Ichikawa A. Sugimoto Y, Negishi M, Hayashi Y, Namba T, Honda A, Watabe A, Hirata M, Narumiya S, Ichikawa A. Sugimoto Y, Negishi M, Hayashi Y, Namba T, Honda A, Watabe A, Hirata M, Narumiya S, Ichikawa A. Two isoforms of the EP3 receptor with different carboxyl-terminal domains: Identical ligand binding properties and different coupling properties with Gi proteins Two isoforms of the EP3 receptor with different carboxyl-terminal domains: Identical ligand binding properties and different coupling properties with Gi proteins Two isoforms of the EP3 receptor with different carboxyl-terminal domains: Identical ligand binding properties and different coupling properties with Gi proteins Journal of Biological Chemistry, 268, 4, 2712-2718 Journal of Biological Chemistry, 268, 4, 2712-2718 Journal of Biological Chemistry, 268, 4, 2712-2718 1993 公開
Hayashi Y, Tanabe Y, Aramori I, Masu M, Shimamoto K, Ohfune Y, Nakanishi S. Hayashi Y, Tanabe Y, Aramori I, Masu M, Shimamoto K, Ohfune Y, Nakanishi S. Hayashi Y, Tanabe Y, Aramori I, Masu M, Shimamoto K, Ohfune Y, Nakanishi S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells British Journal of Pharmacology, 107, 2, 539-543 British Journal of Pharmacology, 107, 2, 539-543 British Journal of Pharmacology, 107, 2, 539-543 1992 公開
Sugimoto Y, Namba T, Honda A, Hayashi Y, Negishi M, Ichikawa A, Narumiya S. Sugimoto Y, Namba T, Honda A, Hayashi Y, Negishi M, Ichikawa A, Narumiya S. Sugimoto Y, Namba T, Honda A, Hayashi Y, Negishi M, Ichikawa A, Narumiya S. Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype Journal of Biological Chemistry, 267, 10, 6463-6466 Journal of Biological Chemistry, 267, 10, 6463-6466 Journal of Biological Chemistry, 267, 10, 6463-6466 1992 公開
Namba T, Sugimoto Y, Hirata M, Hayashi Y, Honda A, Watabe A, Negishi M, Ichikawa A, Narumiya S. Namba T, Sugimoto Y, Hirata M, Hayashi Y, Honda A, Watabe A, Negishi M, Ichikawa A, Narumiya S. Namba T, Sugimoto Y, Hirata M, Hayashi Y, Honda A, Watabe A, Negishi M, Ichikawa A, Narumiya S. Mouse thromboxane A2 receptor: cDNA cloning, expression and Northern blot analysis Mouse thromboxane A2 receptor: cDNA cloning, expression and Northern blot analysis Mouse thromboxane A2 receptor: cDNA cloning, expression and Northern blot analysis Biochemical and Biophysical Research Communications, 184, 3, 1197-1203 Biochemical and Biophysical Research Communications, 184, 3, 1197-1203 Biochemical and Biophysical Research Communications, 184, 3, 1197-1203 1992 公開
Hirata M, Hayashi Y, Ushikubi F, Yokota Y, Kageyama R, Nakanishi S, Narumiya S. Hirata M, Hayashi Y, Ushikubi F, Yokota Y, Kageyama R, Nakanishi S, Narumiya S. Hirata M, Hayashi Y, Ushikubi F, Yokota Y, Kageyama R, Nakanishi S, Narumiya S. Cloning and expression of cDNA for a human thromboxane A2 receptor Cloning and expression of cDNA for a human thromboxane A2 receptor Cloning and expression of cDNA for a human thromboxane A2 receptor Nature, 349, 6310, 617-620 Nature, 349, 6310, 617-620 Nature, 349, 6310, 617-620 1991 公開
Koshimura K, Miwa S, Lee K, Hayashi Y, Hasegawa H, Hamahata K, Fujiwara M, Kimura M, Itokawa Y. Koshimura K, Miwa S, Lee K, Hayashi Y, Hasegawa H, Hamahata K, Fujiwara M, Kimura M, Itokawa Y. Koshimura K, Miwa S, Lee K, Hayashi Y, Hasegawa H, Hamahata K, Fujiwara M, Kimura M, Itokawa Y. Effects of choline administration on in vivo release and biosynthesis of acetylcholine in the rat striatum as studied by in vivo brain microdialysis Effects of choline administration on in vivo release and biosynthesis of acetylcholine in the rat striatum as studied by in vivo brain microdialysis Effects of choline administration on in vivo release and biosynthesis of acetylcholine in the rat striatum as studied by in vivo brain microdialysis Journal of Neurochemistry, 54, 2, 533-539 Journal of Neurochemistry, 54, 2, 533-539 Journal of Neurochemistry, 54, 2, 533-539 1990 公開
Hayashi Y, Miwa S, Lee K, Koshimura K, Hamahata K, Hasegawa H, Fujiwara M, Watanabe Y. Hayashi Y, Miwa S, Lee K, Koshimura K, Hamahata K, Hasegawa H, Fujiwara M, Watanabe Y. Hayashi Y, Miwa S, Lee K, Koshimura K, Hamahata K, Hasegawa H, Fujiwara M, Watanabe Y. Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions Journal of Neurochemistry, 54, 4, 1115-1121 Journal of Neurochemistry, 54, 4, 1115-1121 Journal of Neurochemistry, 54, 4, 1115-1121 1990 公開
Lee K, Miwa S, Hayashi Y, Koshimura K, Fujiwara M, Orii Y. Lee K, Miwa S, Hayashi Y, Koshimura K, Fujiwara M, Orii Y. Lee K, Miwa S, Hayashi Y, Koshimura K, Fujiwara M, Orii Y. Effects of hypoxia on noradrenaline release and neuronal reuptake in isolated rabbit thoracic aortic strips Effects of hypoxia on noradrenaline release and neuronal reuptake in isolated rabbit thoracic aortic strips Effects of hypoxia on noradrenaline release and neuronal reuptake in isolated rabbit thoracic aortic strips Naunyn-Schmiedeberg's Archives of Pharmacology, 339, 5, 503-508 Naunyn-Schmiedeberg's Archives of Pharmacology, 339, 5, 503-508 Naunyn-Schmiedeberg's Archives of Pharmacology, 339, 5, 503-508 1989 公開
Hayashi Y, Miwa S, Lee K, Koshimura K, Kamei A, Hamahata K, Fujiwara M. Hayashi Y, Miwa S, Lee K, Koshimura K, Kamei A, Hamahata K, Fujiwara M. Hayashi Y, Miwa S, Lee K, Koshimura K, Kamei A, Hamahata K, Fujiwara M. A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland A nonisotopic method for determination of the in vivo activities of tyrosine hydroxylase in the rat adrenal gland Analytical Biochemistry, 168, 1, 176-183 Analytical Biochemistry, 168, 1, 176-183 Analytical Biochemistry, 168, 1, 176-183 1988 公開
Lee K, Miwa S, Hayashi Y, Koshimura K, Taniguchi T, Orii Y, Fujiwara M. Lee K, Miwa S, Hayashi Y, Koshimura K, Taniguchi T, Orii Y, Fujiwara M. Lee K, Miwa S, Hayashi Y, Koshimura K, Taniguchi T, Orii Y, Fujiwara M. Effects of hypoxia on contractile responses of rabbit aortic strips to transmural electrical stimulation Effects of hypoxia on contractile responses of rabbit aortic strips to transmural electrical stimulation Effects of hypoxia on contractile responses of rabbit aortic strips to transmural electrical stimulation Naunyn-Schmiedeberg's Archives of Pharmacology, 338, 3, 275-281 Naunyn-Schmiedeberg's Archives of Pharmacology, 338, 3, 275-281 Naunyn-Schmiedeberg's Archives of Pharmacology, 338, 3, 275-281 1988 公開

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タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
Molecular mechanism of structural plasticity of dendritic spine[招待あり] Molecular mechanism of structural plasticity of dendritic spine [招待あり] Molecular mechanism of structural plasticity of dendritic spine [招待あり] Universidad autonoma de Madrid, Spain Universidad autonoma de Madrid, Spain 2011/07 英語 公開
Phosphoisotype analysis of AMPA receptor GluR1 Phosphoisotype analysis of AMPA receptor GluR1 Phosphoisotype analysis of AMPA receptor GluR1 Gordon Research Conference Excitatory Synapsese & Brain Function Gordon Research Conference Excitatory Synapsese & Brain Function Gordon Research Conference Excitatory Synapsese & Brain Function 2011/06 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
挑戦的研究(萌芽) 代表 意思決定における海馬の行動予想発火の役割 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(A) 代表 記憶形成、固定化と想起においてNMDA受容体依存性LTPがおこる時間枠の探索 (平成29年度分) 2017/04/01〜2018/03/31
新学術領域研究(研究領域提案型) 代表 NMDA受容体依存性LTPの制御のための光プローブの作成 (平成29年度分) 2017/04/01〜2018/03/31
新学術領域研究(研究領域提案型) 代表 記憶形成、固定、想起における海馬背側CA1セルアセンブリの長期可視化 (平成29年度分) 2017/04/01〜2018/03/31
挑戦的研究(萌芽) 代表 意思決定における海馬の行動予想発火の役割 (平成30年度分) 2018/04/01〜2019/03/31
基盤研究(A) 代表 記憶形成、固定化と想起においてNMDA受容体依存性LTPがおこる時間枠の探索 (平成30年度分) 2018/04/01〜2019/03/31
新学術領域研究(研究領域提案型) 代表 光による特定の神経細胞への記憶のエンコーディング (平成30年度分) 2018/04/01〜2019/03/31
新学術領域研究(研究領域提案型) 代表 シナプス操作によるPTSDの構成的理解 (平成30年度分) 2018/04/01〜2019/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
B7a 薬理学 Pharmacology 後期前半 医学部 2017/04〜2018/03
B7b 薬理学実習 Laboratory Course in Pharmacology 後期前半 医学部 2017/04〜2018/03
医科学研究 Laboratory visit 前期不定 医学研究科 2017/04〜2018/03
薬理学 II Pharmacology II 後期不定 医学研究科 2017/04〜2018/03
薬理学 I Pharmacology I 後期不定 医学研究科 2017/04〜2018/03
薬理学 Pharmacology 後期不定 医学研究科 2017/04〜2018/03
薬理学 II Pharmacology II 前期不定 医学研究科 2019/04〜2020/03
薬理学 I Pharmacology I 前期不定 医学研究科 2019/04〜2020/03
薬理学 Pharmacology 前期不定 医学研究科 2019/04〜2020/03
全学運営(役職等)
役職名 期間
学生生活委員会 委員 2019/03/01〜2021/03/31
学生生活委員会第三小委員会 委員 2019/03/01〜2021/03/31
部局運営(役職等)
役職名 期間
教授選考方針検討委員会 2016/11/01〜2018/10/31
兼業審査委員会 2017/09/25〜2019/09/24
兼業審査小委員会 2017/09/25〜2019/09/24
大学評価部局委員会 2018/04/01〜2020/03/31
医学研究科運営委員会 〜2020/09/30
学務委員会委員 2018/04/01〜2020/03/31
国際交流委員会 2018/10/01〜2020/09/30
動物実験委員会 2018/10/01〜2020/09/30
動物実験施設管理委員会 2018/10/01〜2020/03/31
医学図書館運営委員会 2019/04/01〜2021/03/31
図書連絡委員名簿
医学研究科等防犯カメラ設置運用委員会 2019/04/01〜2021/03/31
大倉辰三郎・喜美奨学金選考小委員会 2018/04/01〜2020/03/31
京都大学医学部・病院構内交通委員会(基礎系) 2018/04/01〜2020/03/31

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