大橋 真也

最終更新日時: 2019/06/26 18:28:25

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氏名(漢字/フリガナ/アルファベット表記)
大橋 真也/オオハシ シンヤ/Oohashi, Shinya
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/内科(腫瘍内科)/助教
電子メールアドレス
メールアドレス
ohashish @ kuhp.kyoto-u.ac.jp
所属学会(国内)
学会名(日本語) 学会名(英語)
日本内科学会
日本消化器病学会
日本消化器内視鏡学会
日本癌学会
日本食道学会
日本消化管学会
日本消化器がん検診学会
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
researchmap URL
https://researchmap.jp/7000009271
研究テーマ
(日本語)
食道扁平上皮癌発がんのメカニズム
(英語)
Elucidation a mechanism of esophageal cancer development
研究概要
(日本語)
食道扁平上皮発がんのメカニズムについて、特にアルコールの代謝過程で生成されるアセトアルデヒドによる発がん機序についてヒト食道扁平上皮細胞を用いたin vitro研究、ALDH2遺伝子改変マウスを用いたin vivo研究を行っている。また食道癌に対する新たな抗がん療法の開発を目指した基礎研究、臨床研究を実施している。
(英語)
We are conducting in vitro studies using human esophageal epithelial cells, and in vivo studies using ALDH2 genetically modified mice to elucidate the molecular mechanisms of esophageal squamous carcinogenesis, in particularly focusing on acetaldehyde which is generated from alcohol metabolism. We are also conducting basic and/or clinical research aimed at developing novel anticancer therapy for esophageal cancer.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
食道癌 Esophageal cancer
アルコール発がん Alcohol-related carcinogenesis
アセトアルデヒド acetaldehyde
アルデヒド脱水素酵素(ALDH2) ALDH2
DNA修復応答 DNA damage response
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
大橋 真也 大橋 真也 Hirohashi K, Ohashi S, Amanuma Y, Nakai Y, Ida T, Baba K, Mitani Y, Mizumoto A, Yamamoto Y, Kikuchi O, Matsubara J, Yamada A, Miyamoto S, Seno H, Matsuda T, Muto M. Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2(Glu504Lys) knock-in mice. Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2(Glu504Lys) knock-in mice. Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2(Glu504Lys) knock-in mice. Carcinogenesis Carcinogenesis Carcinogenesis 2019 英語 公開
大橋 真也 大橋 真也 Mizumoto A, Ohashi S, Kamada M, Saito T, Nakai Y, Baba K, Hirohashi K, Mitani Y, Kikuchi O, Matsubara J, Yamada A, Takahashi T, Lee H, Okuno Y, Kanai M, Muto M. Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma. Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma. Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma. J Gastroenterology J Gastroenterology J Gastroenterology 2019 英語 研究論文(学術雑誌) 公開
大橋 真也 大橋 真也 Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y, Shiozawa Y, Sato Y, Aoki K, Kim SK, Fujii Y, Yoshida K, Kataoka K, Nakagawa M, Inoue S, Hirano T, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Nishikawa Y, Amanuma Y, Ohashi S, Aoyama I, Horimatsu T, Miyamoto S, Tsunoda S, Sakai Y, Narahara M, Brown JB, Sato Y, Sawada G, Mimori K, Minamiguchi S, Haga S, Seno H, Miyano S, Makishima H, Muto M, Ogawa S. Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature Nature Nature 2019 英語 公開
大橋 真也 大橋 真也 Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, Shinden Y, Sasaki K, Omoto I, Kita Y, Muto M, Bass AJ, Diehl JA, Ginsberg GG, Doki Y, Mori M, Uchikado Y, Arigami T, Avadhani NG, Basu D, Rustgi AK, Natsugoe S Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells. Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells. Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells. Cell Mel Gastroenterol Hepatol, 7, 1, 73-91 Cell Mel Gastroenterol Hepatol, 7, 1, 73-91 Cell Mel Gastroenterol Hepatol, 7, 1, 73-91 2019 英語 公開
大橋 真也 大橋 真也 Karakasheva TA, Lin EW, Tang Q, Qiao E, Waldron TJ, Soni M, Klein-Szanto AJ, Sahu V, Basu D, Ohashi S, Baba K, Giaccone ZT, Wallker SR, Frank DA, Wileyto EP, Long Q, Dunagin M, Raj A, Diehl JA, Bass AJ, Rustgi AK. IL-6 mediates cross-talk between activated fibroblasts and tumor cells in the tumor microenvironment. IL-6 mediates cross-talk between activated fibroblasts and tumor cells in the tumor microenvironment. IL-6 mediates cross-talk between activated fibroblasts and tumor cells in the tumor microenvironment. Cancer Res, 78, 17, 4957-4970 Cancer Res, 78, 17, 4957-4970 Cancer Res, 78, 17, 4957-4970 2018 公開
大橋 真也 大橋 真也 アルコール代謝と頭頚部癌 -広域発がん現象ー アルコール代謝と頭頚部癌 -広域発がん現象ー 日本臨床増刊号, 75, 96-101 日本臨床増刊号, 75, 96-101 , 75, 96-101 2017/02 日本語 公開
大橋 真也 大橋 真也 Aoyama I, Ohashi S, Amanuma Y, Hirohashi K, Mizumoto A, Funakoshi M, Tsurumaki M, Nakai Y, Tanaka K, hanada M, Uesaka A, Chiba T, Muto M Establishment of a quick and highly available accurate breath test for ALDH2 genotyping Establishment of a quick and highly available accurate breath test for ALDH2 genotyping Establishment of a quick and highly available accurate breath test for ALDH2 genotyping Clinical and Translational Gastroenterology, 8, 6, e96 Clinical and Translational Gastroenterology, 8, 6, e96 Clinical and Translational Gastroenterology, 8, 6, e96 2017 英語 研究論文(学術雑誌) 公開
大橋 真也 大橋 真也 Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M. Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells J Exp Clin Cancer Res, 36, 1, 101 J Exp Clin Cancer Res, 36, 1, 101 J Exp Clin Cancer Res, 36, 1, 101 2017 英語 公開
大橋 真也 大橋 真也 Mizumoto A, Ohashi S, Hirohashi K, Amanuma Y, Matsuda T, Muto M. Molecular mechanisms of acetaldehyde-mediated carcinogenesis in squamous epithelium Molecular mechanisms of acetaldehyde-mediated carcinogenesis in squamous epithelium. Molecular mechanisms of acetaldehyde-mediated carcinogenesis in squamous epithelium. Molecular mechanisms of acetaldehyde-mediated carcinogenesis in squamous epithelium. Int J Mol Sci, 18, 1943 Int J Mol Sci, 18, 1943 Int J Mol Sci, 18, 1943 2017 英語 公開
大橋 真也 大橋 真也 食道扁平上皮発がんと遺伝子異常 食道扁平上皮発がんと遺伝子異常 日本消化器病学会雑誌, 113, 11, 1857-67 日本消化器病学会雑誌, 113, 11, 1857-67 , 113, 11, 1857-67 2016/11 日本語 公開
Kikuchi O, Ohashi S, Nakai Y, Nakagawa S, Matsuoka K, Kobunai T, Takechi T, Amanuma Y, Yoshioka M, Ida T, Yamamoto Y, Okuno Y, Miyamoto S, Nakagawa H, Matsubara K, Chiba T, Muto M. Kikuchi O, Ohashi S, Nakai Y, Nakagawa S, Matsuoka K, Kobunai T, Takechi T, Amanuma Y, Yoshioka M, Ida T, Yamamoto Y, Okuno Y, Miyamoto S, Nakagawa H, Matsubara K, Chiba T, Muto M. Kikuchi O, Ohashi S, Nakai Y, Nakagawa S, Matsuoka K, Kobunai T, Takechi T, Amanuma Y, Yoshioka M, Ida T, Yamamoto Y, Okuno Y, Miyamoto S, Nakagawa H, Matsubara K, Chiba T, Muto M. ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds Am J Cancer Res, 6, 4, 781-796 , 6, 4, 781-796 Am J Cancer Res, 6, 4, 781-796 2016/03 英語 公開
大橋 真也 大橋 真也 Kikuchi O, Ohashi S, Horibe T, Kohno M, Nakai Y, Miyamoto S, Chiba T, Muto M, Kawakami K. Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma Scientific Reports, 6, 22452 Scientific Reports, 6, 22452 Scientific Reports, 6, 22452 2016/03 英語 公開
大橋 真也 大橋 真也 Katada C, Yokoyama T, Yano T, Kaneko T, Oda I, Shimizu Y, Doyama H, Koike T, Takizawa K, Hirao M, Okada H, Yoshii T, Konishi K, Yamanouchi T, Tsuda T, Omori T, Kobayashi N, Shimoda T, Ochiai A, Amanuma Y, Ohashi S, Matsuda T, Ishikawa H, Yokoyama A, Muto M Alcohol consumption and multiple dysplastic lesions increase risk of squamous cell carcinoma in the esophagus, head, and neck Alcohol consumption and multiple dysplastic lesions increase risk of squamous cell carcinoma in the esophagus, head, and neck Alcohol consumption and multiple dysplastic lesions increase risk of squamous cell carcinoma in the esophagus, head, and neck Gastroenterology, 151, 860-869 Gastroenterology, 151, 860-869 Gastroenterology, 151, 860-869 2016 英語 公開
大橋 真也 大橋 真也 Shinya Ohashi Recent Advances from Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma. Recent Advances from Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma. Recent Advances from Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma. Gastroenterology, 149, 7, 1700-1715 Gastroenterology, 149, 7, 1700-1715 Gastroenterology, 149, 7, 1700-1715 2015/12 英語 公開
Yusuke Amanuma, Shinya Ohashi, et al. Yusuke Amanuma, Shinya Ohashi, et al. Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium. Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium. Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium. Scientific Reports, 5, 14142 Scientific Reports, 5, 14142 Scientific Reports, 5, 14142 2015/09 英語 公開
大橋 真也 大橋 真也 Sato F, Kubota Y, Natsuizaka M, Maehara O, Hatanaka Y, Marukawa K, Terashita K, Suda G, Ohnishi S, Shimizu Y, Komatsu Y, Ohashi S, Kagawa S, Kinugasa H, Whelan KA, Nakagawa H, Sakamoto N EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial mesenchymal transition EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial mesenchymal transition EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial mesenchymal transition Cancer Biology & Therapy, 16, 6, 933-940 Cancer Biology & Therapy, 16, 6, 933-940 Cancer Biology & Therapy, 16, 6, 933-940 2015/06 英語 研究論文(学術雑誌) 公開
大橋 真也 大橋 真也 Kagawa S, Natsuizaka M, Whelan KA,Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities Oncogene, 34, 18, 2347-2359 Oncogene, 34, 18, 2347-2359 Oncogene, 34, 18, 2347-2359 2015/04 英語 研究論文(学術雑誌) 公開
大橋 真也 大橋 真也 Shinya Ohashi Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression Am J Cancer Res, 5, 8, 2431-2440 Am J Cancer Res, 5, 8, 2431-2440 Am J Cancer Res, 5, 8, 2431-2440 2015 英語 公開
大橋 真也 大橋 真也 Yukawa Y, Ohashi S, Amanuma Y, Nakai Y, Tsurumaki M, Kikuchi O, Miyamoto S, Oyama T, Kawamoto T, Chiba T, Matsuda T, Muto M Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion American Journal of Cancer Research, 4, 3, 279-284 American Journal of Cancer Research, 4, 3, 279-284 American Journal of Cancer Research, 4, 3, 279-284 2014/04 英語 研究論文(学術雑誌) 公開
大橋 真也 大橋 真也 Ohashi S, Kikuchi O, Tsurumaki M, Nakai Y, Kasai H, Horimatsu T, Miyamoto S, Shimizu A, Chiba T, Muto M Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma PLOS ONE, 9, 8, e103126 PLOS ONE, 9, 8, e103126 PLOS ONE, 9, 8, e103126 2014 英語 研究論文(学術雑誌) 公開
M. Natsuizaka; S. Naganuma; S. Kagawa; S. Ohashi; A. Ahmadi; H. Subramanian; S. Chang; K.J. Nakagawa; X. Ji; S.A. Liebhaber; A.J. Klein-Szanto; H. Nakagawa M. Natsuizaka; S. Naganuma; S. Kagawa; S. Ohashi; A. Ahmadi; H. Subramanian; S. Chang; K.J. Nakagawa; X. Ji; S.A. Liebhaber; A.J. Klein-Szanto; H. Nakagawa M. Natsuizaka; S. Naganuma; S. Kagawa; S. Ohashi; A. Ahmadi; H. Subramanian; S. Chang; K.J. Nakagawa; X. Ji; S.A. Liebhaber; A.J. Klein-Szanto; H. Nakagawa Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis FASEB Journal, 26, 6, 2620-2630 FASEB Journal, 26, 6, 2620-2630 FASEB Journal, 26, 6, 2620-2630 2012/06 英語 公開
Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhodes B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, klein-Szanto AJ, Nakagawa H Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhodes B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, klein-Szanto AJ, Nakagawa H Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhodes B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, klein-Szanto AJ, Nakagawa H Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma Am J Cancer Res Am J Cancer Res Am J Cancer Res 2012 英語 公開
S. Ohashi; M. Natsuizaka; S. Naganuma; S. Kagawa; S. Kimura; H. Itoh; R.A. Kalman; M. Nakagawa; D.S. Darling; D. Basu; P.A. Gimotty; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; H. Nakagawa S. Ohashi; M. Natsuizaka; S. Naganuma; S. Kagawa; S. Kimura; H. Itoh; R.A. Kalman; M. Nakagawa; D.S. Darling; D. Basu; P.A. Gimotty; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; H. Nakagawa S. Ohashi; M. Natsuizaka; S. Naganuma; S. Kagawa; S. Kimura; H. Itoh; R.A. Kalman; M. Nakagawa; D.S. Darling; D. Basu; P.A. Gimotty; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; H. Nakagawa A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors Cancer Research, 71, 21, 6836-6847 Cancer Research, 71, 21, 6836-6847 Cancer Research, 71, 21, 6836-6847 2011 英語 公開
S. Ohashi; M. Natsuizaka; H. Nakagawa S. Ohashi; M. Natsuizaka; H. Nakagawa S. Ohashi; M. Natsuizaka; H. Nakagawa MMP7 and activation of IGF1R A new insight into anti-EGFR therapeutic resistance in metastatic colorectal cancer MMP7 and activation of IGF1R A new insight into anti-EGFR therapeutic resistance in metastatic colorectal cancer MMP7 and activation of IGF1R A new insight into anti-EGFR therapeutic resistance in metastatic colorectal cancer Cancer Biology and Therapy, 11, 2, 184-187 Cancer Biology and Therapy, 11, 2, 184-187 Cancer Biology and Therapy, 11, 2, 184-187 2011 英語 公開
M. Watanabe; T. Kou; Y. Nishikawa; Y. Sakuma; N. Kumagai; Y. Oda; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; S. Yazumi M. Watanabe; T. Kou; Y. Nishikawa; Y. Sakuma; N. Kumagai; Y. Oda; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; S. Yazumi M. Watanabe; T. Kou; Y. Nishikawa; Y. Sakuma; N. Kumagai; Y. Oda; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; S. Yazumi Perforation of the sigmoid colon by an ingested fish bone Perforation of the sigmoid colon by an ingested fish bone Perforation of the sigmoid colon by an ingested fish bone Internal Medicine, 49, 11, 1041-1042 Internal Medicine, 49, 11, 1041-1042 Internal Medicine, 49, 11, 1041-1042 2010 英語 公開
S. Ohashi; M. Natsuizaka; Y. Yashiroohtani; R.A. Kalman; M. Nakagawa; L. Wu; A.J. Kleinszanto; M. Herlyn; J.A. Diehl; J.P. Katz; W.S. Pear; J.T. Seykora; H. Nakagawa S. Ohashi; M. Natsuizaka; Y. Yashiroohtani; R.A. Kalman; M. Nakagawa; L. Wu; A.J. Kleinszanto; M. Herlyn; J.A. Diehl; J.P. Katz; W.S. Pear; J.T. Seykora; H. Nakagawa S. Ohashi; M. Natsuizaka; Y. Yashiroohtani; R.A. Kalman; M. Nakagawa; L. Wu; A.J. Kleinszanto; M. Herlyn; J.A. Diehl; J.P. Katz; W.S. Pear; J.T. Seykora; H. Nakagawa NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a csl-dependent transcriptional network NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a csl-dependent transcriptional network NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a csl-dependent transcriptional network Gastroenterology, 139, 6, 2113-2123 Gastroenterology, 139, 6, 2113-2123 Gastroenterology, 139, 6, 2113-2123 2010 英語 公開
M. Natsuizaka; S. Ohashi; G.S. Wong; A. Ahmadi; R.A. Kalman; D. Budo; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; H. Nakagawa M. Natsuizaka; S. Ohashi; G.S. Wong; A. Ahmadi; R.A. Kalman; D. Budo; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; H. Nakagawa M. Natsuizaka; S. Ohashi; G.S. Wong; A. Ahmadi; R.A. Kalman; D. Budo; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; H. Nakagawa Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells Carcinogenesis, 31, 8, 1344-1353 Carcinogenesis, 31, 8, 1344-1353 Carcinogenesis, 31, 8, 1344-1353 2010 英語 公開
S. Ohashi; M. Natsuizaka; G.S. Wong; C.Z. Michaylira; K.D. Grugan; D.B. Stairs; J. Kalabis; M.E. Vega; R.A. Kalman; M. Nakagawa; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; A.K. Rustgi; H. Nakagawa S. Ohashi; M. Natsuizaka; G.S. Wong; C.Z. Michaylira; K.D. Grugan; D.B. Stairs; J. Kalabis; M.E. Vega; R.A. Kalman; M. Nakagawa; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; A.K. Rustgi; H. Nakagawa S. Ohashi; M. Natsuizaka; G.S. Wong; C.Z. Michaylira; K.D. Grugan; D.B. Stairs; J. Kalabis; M.E. Vega; R.A. Kalman; M. Nakagawa; A.J. Klein-Szanto; M. Herlyn; J.A. Diehl; A.K. Rustgi; H. Nakagawa Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors Cancer Research, 70, 10, 4174-4184 Cancer Research, 70, 10, 4174-4184 Cancer Research, 70, 10, 4174-4184 2010 英語 公開
J.J. Lee; M. Natsuizaka; S. Ohashi; G.S. Wong; M. Takaoka; C.Z. Michaylira; D. Budo; J.W. Tobias; M. Kanai; Y. Shirakawa; Y. Naomoto; A.J.P. Klein-Szanto; V.H. Haase; H. Nakagawa J.J. Lee; M. Natsuizaka; S. Ohashi; G.S. Wong; M. Takaoka; C.Z. Michaylira; D. Budo; J.W. Tobias; M. Kanai; Y. Shirakawa; Y. Naomoto; A.J.P. Klein-Szanto; V.H. Haase; H. Nakagawa J.J. Lee; M. Natsuizaka; S. Ohashi; G.S. Wong; M. Takaoka; C.Z. Michaylira; D. Budo; J.W. Tobias; M. Kanai; Y. Shirakawa; Y. Naomoto; A.J.P. Klein-Szanto; V.H. Haase; H. Nakagawa Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis Carcinogenesis, 31, 3, 427-434 Carcinogenesis, 31, 3, 427-434 Carcinogenesis, 31, 3, 427-434 2010 英語 公開
Y. Oda; T. Kou; M. Watanabe; Y. Sakuma; N. Taguchi; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; H. Ito; T. Nakamura; S. Yazumi Y. Oda; T. Kou; M. Watanabe; Y. Sakuma; N. Taguchi; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; H. Ito; T. Nakamura; S. Yazumi Y. Oda; T. Kou; M. Watanabe; Y. Sakuma; N. Taguchi; Y. Kato; Y. Kudo; A. Yamauchi; Y. Sugiura; S. Ohashi; M. Asada; T. Fukunaga; K. Kawaguchi; H. Ito; T. Nakamura; S. Yazumi Regression of B-cell lymphoma of the liver with hepatitis C virus infection after treatment with pegylated interferon-α and ribavirin Regression of B-cell lymphoma of the liver with hepatitis C virus infection after treatment with pegylated interferon-α and ribavirin Regression of B-cell lymphoma of the liver with hepatitis C virus infection after treatment with pegylated interferon-α and ribavirin Digestive Diseases and Sciences, 55, 6, 1791-1793 Digestive Diseases and Sciences, 55, 6, 1791-1793 Digestive Diseases and Sciences, 55, 6, 1791-1793 2010 英語 公開
D.B. Stairs; S. Ohashi; H. Nakagawa D.B. Stairs; S. Ohashi; H. Nakagawa D.B. Stairs; S. Ohashi; H. Nakagawa Cellular biometrics in the postgenomics era Cellular biometrics in the postgenomics era Cellular biometrics in the postgenomics era Cancer Biology and Therapy, 7, 11, 1756-1757 Cancer Biology and Therapy, 7, 11, 1756-1757 Cancer Biology and Therapy, 7, 11, 1756-1757 2008 英語 公開
K. Kiriya; N. Watanabe; A. Nishio; K. Okazaki; M. Kido; K. Saga; J. Tanaka; T. Akamatsu; S. Ohashi; M. Asada; T. Fukui; T. Chiba K. Kiriya; N. Watanabe; A. Nishio; K. Okazaki; M. Kido; K. Saga; J. Tanaka; T. Akamatsu; S. Ohashi; M. Asada; T. Fukui; T. Chiba K. Kiriya; N. Watanabe; A. Nishio; K. Okazaki; M. Kido; K. Saga; J. Tanaka; T. Akamatsu; S. Ohashi; M. Asada; T. Fukui; T. Chiba Essential role of Peyer\\'s patches in the development of Helicobacter-induced gastritis Essential role of Peyer\\'s patches in the development of Helicobacter-induced gastritis Essential role of Peyer\\'s patches in the development of Helicobacter-induced gastritis International Immunology, 19, 4, 435-446 International Immunology, 19, 4, 435-446 International Immunology, 19, 4, 435-446 2007 英語 公開
T. Fukui; A. Nishio; K. Okazaki; K. Kasahara; K. Saga; J. Tanaka; N. Uza; S. Ueno; M. Kido; S. Ohashi; M. Asada; H. Nakase; N. Watanabe; T. Chiba T. Fukui; A. Nishio; K. Okazaki; K. Kasahara; K. Saga; J. Tanaka; N. Uza; S. Ueno; M. Kido; S. Ohashi; M. Asada; H. Nakase; N. Watanabe; T. Chiba T. Fukui; A. Nishio; K. Okazaki; K. Kasahara; K. Saga; J. Tanaka; N. Uza; S. Ueno; M. Kido; S. Ohashi; M. Asada; H. Nakase; N. Watanabe; T. Chiba Cross-primed CD8<sup>+</sup> cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4<sup>+</sup> T cells Cross-primed CD8<sup>+</sup> cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4<sup>+</sup> T cells Cross-primed CD8<sup>+</sup> cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4<sup>+</sup> T cells Helicobacter, 12, 5, 486-497 Helicobacter, 12, 5, 486-497 Helicobacter, 12, 5, 486-497 2007 英語 公開
S. Ohashi; A. Nishio; H. Nakamura; M. Kido; S. Ueno; N. Uza; S. Inoue; H. Kitamura; K. Kiriya; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; T. Fukui; N. Watanabe; H. Nakase; J. Yodoi; K. Okazaki; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Kido; S. Ueno; N. Uza; S. Inoue; H. Kitamura; K. Kiriya; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; T. Fukui; N. Watanabe; H. Nakase; J. Yodoi; K. Okazaki; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Kido; S. Ueno; N. Uza; S. Inoue; H. Kitamura; K. Kiriya; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; T. Fukui; N. Watanabe; H. Nakase; J. Yodoi; K. Okazaki; T. Chiba Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis American Journal of Physiology - Gastrointestinal and Liver Physiology, 290, 4, G772-G781 American Journal of Physiology - Gastrointestinal and Liver Physiology, 290, 4, G772-G781 American Journal of Physiology - Gastrointestinal and Liver Physiology, 290, 4, G772-G781 2006 英語 公開
T. Fukui; A. Nishio; K. Okazaki; N. Uza; S. Ueno; M. Kido; S. Inoue; H. Kitamura; K. Kiriya; S. Ohashi; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; K. Suzuki; K. Uchida; H. Fukui; H. Nakase; N. Watanabe; T. Chiba T. Fukui; A. Nishio; K. Okazaki; N. Uza; S. Ueno; M. Kido; S. Inoue; H. Kitamura; K. Kiriya; S. Ohashi; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; K. Suzuki; K. Uchida; H. Fukui; H. Nakase; N. Watanabe; T. Chiba T. Fukui; A. Nishio; K. Okazaki; N. Uza; S. Ueno; M. Kido; S. Inoue; H. Kitamura; K. Kiriya; S. Ohashi; M. Asada; H. Tamaki; M. Matsuura; K. Kawasaki; K. Suzuki; K. Uchida; H. Fukui; H. Nakase; N. Watanabe; T. Chiba Gastric mucosal hyperplasia via upregulation of gastrin induced by persistent activation of gastric innate immunity in major histocompatibility complex class II deficient mice Gastric mucosal hyperplasia via upregulation of gastrin induced by persistent activation of gastric innate immunity in major histocompatibility complex class II deficient mice Gastric mucosal hyperplasia via upregulation of gastrin induced by persistent activation of gastric innate immunity in major histocompatibility complex class II deficient mice Gut, 55, 5, 607-615 Gut, 55, 5, 607-615 Gut, 55, 5, 607-615 2006 英語 公開
S. Ohashi; A. Nishio; H. Nakamura; M. Kido; K. Kiriya; M. Asada; H. Tamaki; T. Fukui; K. Kawasaki; N. Watanabe; J. Yodoi; K. Okazaki; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Kido; K. Kiriya; M. Asada; H. Tamaki; T. Fukui; K. Kawasaki; N. Watanabe; J. Yodoi; K. Okazaki; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Kido; K. Kiriya; M. Asada; H. Tamaki; T. Fukui; K. Kawasaki; N. Watanabe; J. Yodoi; K. Okazaki; T. Chiba Clinical significance of serum thioredoxin 1 levels in patients with acute pancreatitis Clinical significance of serum thioredoxin 1 levels in patients with acute pancreatitis Clinical significance of serum thioredoxin 1 levels in patients with acute pancreatitis Pancreas, 32, 3, 264-270 Pancreas, 32, 3, 264-270 Pancreas, 32, 3, 264-270 2006 英語 公開
M. Asada; A. Nishio; K. Uchida; M. Kido; S. Ueno; N. Uza; K. Kiriya; S. Inoue; H. Kitamura; S. Ohashi; H. Tamaki; T. Fukui; M. Matsuura; K. Kawasaki; T. Nishi; N. Watanabe; H. Nakase; T. Chiba; K. Okazaki M. Asada; A. Nishio; K. Uchida; M. Kido; S. Ueno; N. Uza; K. Kiriya; S. Inoue; H. Kitamura; S. Ohashi; H. Tamaki; T. Fukui; M. Matsuura; K. Kawasaki; T. Nishi; N. Watanabe; H. Nakase; T. Chiba; K. Okazaki M. Asada; A. Nishio; K. Uchida; M. Kido; S. Ueno; N. Uza; K. Kiriya; S. Inoue; H. Kitamura; S. Ohashi; H. Tamaki; T. Fukui; M. Matsuura; K. Kawasaki; T. Nishi; N. Watanabe; H. Nakase; T. Chiba; K. Okazaki Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis Pancreas, 33, 1, 20-26 Pancreas, 33, 1, 20-26 Pancreas, 33, 1, 20-26 2006 英語 公開
S. Ohashi; S. Yazumi; N. Watanabe; S. Matsumoto; T. Fukui; A. Nishio; T. Chiba S. Ohashi; S. Yazumi; N. Watanabe; S. Matsumoto; T. Fukui; A. Nishio; T. Chiba S. Ohashi; S. Yazumi; N. Watanabe; S. Matsumoto; T. Fukui; A. Nishio; T. Chiba Gastrointestinal: MALT lymphoma of the terminal ileum Gastrointestinal: MALT lymphoma of the terminal ileum Gastrointestinal: MALT lymphoma of the terminal ileum Journal of Gastroenterology and Hepatology (Australia), 21, 9, 1495- Journal of Gastroenterology and Hepatology (Australia), 21, 9, 1495- Journal of Gastroenterology and Hepatology (Australia), 21, 9, 1495- 2006 英語 公開
T. Fukui; T. Sakurai; S. Miyamoto; S. Ueno; M. Kido; K. Kiriya; S. Inoue; S. Ohashi; A. Nishio; T. Chiba T. Fukui; T. Sakurai; S. Miyamoto; S. Ueno; M. Kido; K. Kiriya; S. Inoue; S. Ohashi; A. Nishio; T. Chiba T. Fukui; T. Sakurai; S. Miyamoto; S. Ueno; M. Kido; K. Kiriya; S. Inoue; S. Ohashi; A. Nishio; T. Chiba Gastrointestinal: Epidermal metaplasia of the esophagus Gastrointestinal: Epidermal metaplasia of the esophagus Gastrointestinal: Epidermal metaplasia of the esophagus Journal of Gastroenterology and Hepatology (Australia), 21, 10, 1627- Journal of Gastroenterology and Hepatology (Australia), 21, 10, 1627- Journal of Gastroenterology and Hepatology (Australia), 21, 10, 1627- 2006 英語 公開
H. Tamaki; H. Nakamura; A. Nishio; H. Nakase; S. Ueno; N. Uza; M. Kido; S. Inoue; S. Mikami; M. Asada; K. Kiriya; H. Kitamura; S. Ohashi; T. Fukui; K. Kawasaki; M. Matsuura; Y. Ishii; K. Okazaki; J. Yodoi; T. Chiba H. Tamaki; H. Nakamura; A. Nishio; H. Nakase; S. Ueno; N. Uza; M. Kido; S. Inoue; S. Mikami; M. Asada; K. Kiriya; H. Kitamura; S. Ohashi; T. Fukui; K. Kawasaki; M. Matsuura; Y. Ishii; K. Okazaki; J. Yodoi; T. Chiba H. Tamaki; H. Nakamura; A. Nishio; H. Nakase; S. Ueno; N. Uza; M. Kido; S. Inoue; S. Mikami; M. Asada; K. Kiriya; H. Kitamura; S. Ohashi; T. Fukui; K. Kawasaki; M. Matsuura; Y. Ishii; K. Okazaki; J. Yodoi; T. Chiba Human Thioredoxin-1 Ameliorates Experimental Murine Colitis in Association With Suppressed Macrophage Inhibitory Factor Production Human Thioredoxin-1 Ameliorates Experimental Murine Colitis in Association With Suppressed Macrophage Inhibitory Factor Production Human Thioredoxin-1 Ameliorates Experimental Murine Colitis in Association With Suppressed Macrophage Inhibitory Factor Production Gastroenterology, 131, 4, 1110-1121 Gastroenterology, 131, 4, 1110-1121 Gastroenterology, 131, 4, 1110-1121 2006 英語 公開
S. Ohashi; S. Yazumi; A. Nishio; T. Fukui; M. Asada; T. Chiba S. Ohashi; S. Yazumi; A. Nishio; T. Fukui; M. Asada; T. Chiba S. Ohashi; S. Yazumi; A. Nishio; T. Fukui; M. Asada; T. Chiba Acute cerebral infarction during combination chemotherapy with S-1 cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach Acute cerebral infarction during combination chemotherapy with S-1 cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach Acute cerebral infarction during combination chemotherapy with S-1 cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach Internal Medicine, 45, 18, 1049-1053 Internal Medicine, 45, 18, 1049-1053 Internal Medicine, 45, 18, 1049-1053 2006 英語 公開
S. Ohashi; A. Nishio; H. Nakamura; M. Asada; H. Tamaki; K. Kawasaki; T. Fukui; J. Yodoi; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Asada; H. Tamaki; K. Kawasaki; T. Fukui; J. Yodoi; T. Chiba S. Ohashi; A. Nishio; H. Nakamura; M. Asada; H. Tamaki; K. Kawasaki; T. Fukui; J. Yodoi; T. Chiba Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice Antioxidants and Redox Signaling, 8, 9-10, 1835-1845 Antioxidants and Redox Signaling, 8, 9-10, 1835-1845 Antioxidants and Redox Signaling, 8, 9-10, 1835-1845 2006 英語 公開
M. Matsuura; K. Okazaki; A. Nishio; H. Nakase; H. Tamaki; K. Uchida; T. Nishi; M. Asada; K. Kawasaki; T. Fukui; H. Yoshizawa; S. Ohashi; S. Inoue; C. Kawanami; H. Hiai; Y. Tabata; T. Chiba M. Matsuura; K. Okazaki; A. Nishio; H. Nakase; H. Tamaki; K. Uchida; T. Nishi; M. Asada; K. Kawasaki; T. Fukui; H. Yoshizawa; S. Ohashi; S. Inoue; C. Kawanami; H. Hiai; Y. Tabata; T. Chiba M. Matsuura; K. Okazaki; A. Nishio; H. Nakase; H. Tamaki; K. Uchida; T. Nishi; M. Asada; K. Kawasaki; T. Fukui; H. Yoshizawa; S. Ohashi; S. Inoue; C. Kawanami; H. Hiai; Y. Tabata; T. Chiba Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis Gastroenterology, 128, 4, 975-986 Gastroenterology, 128, 4, 975-986 Gastroenterology, 128, 4, 975-986 2005/04 英語 公開
T. Fukui; K. Okazaki; H. Yoshizawa; S. Ohashi; H. Tamaki; K. Kawasaki; M. Matsuura; M. Asada; H. Nakase; Y. Nakashima; A. Nishio; T. Chiba T. Fukui; K. Okazaki; H. Yoshizawa; S. Ohashi; H. Tamaki; K. Kawasaki; M. Matsuura; M. Asada; H. Nakase; Y. Nakashima; A. Nishio; T. Chiba T. Fukui; K. Okazaki; H. Yoshizawa; S. Ohashi; H. Tamaki; K. Kawasaki; M. Matsuura; M. Asada; H. Nakase; Y. Nakashima; A. Nishio; T. Chiba A case of autoimmune pancreatitis associated with sclerosing cholangitis, retroperitoneal fibrosis and Sjögren\\'s syndrome A case of autoimmune pancreatitis associated with sclerosing cholangitis, retroperitoneal fibrosis and Sjögren\\'s syndrome A case of autoimmune pancreatitis associated with sclerosing cholangitis, retroperitoneal fibrosis and Sjögren\\'s syndrome Pancreatology, 5, 1, 86-91 Pancreatology, 5, 1, 86-91 Pancreatology, 5, 1, 86-91 2005 英語 公開
K. Kawasaki; A. Nishio; H. Nakamura; K. Uchida; T. Fukui; M. Ohana; H. Yoshizawa; S. Ohashi; H. Tamaki; M. Matsuura; M. Asada; T. Nishi; H. Nakase; S. Toyokuni; W. Liu; J. Yodoi; K. Okazaki; T. Chiba K. Kawasaki; A. Nishio; H. Nakamura; K. Uchida; T. Fukui; M. Ohana; H. Yoshizawa; S. Ohashi; H. Tamaki; M. Matsuura; M. Asada; T. Nishi; H. Nakase; S. Toyokuni; W. Liu; J. Yodoi; K. Okazaki; T. Chiba K. Kawasaki; A. Nishio; H. Nakamura; K. Uchida; T. Fukui; M. Ohana; H. Yoshizawa; S. Ohashi; H. Tamaki; M. Matsuura; M. Asada; T. Nishi; H. Nakase; S. Toyokuni; W. Liu; J. Yodoi; K. Okazaki; T. Chiba Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1 Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1 Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1 Laboratory Investigation, 85, 9, 1104-1117 Laboratory Investigation, 85, 9, 1104-1117 Laboratory Investigation, 85, 9, 1104-1117 2005 英語 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
K.D. Grugan; C.G. Miller; Y. Yao; C.Z. Michaylira; S. Ohashi; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; M. Han; H. Nakagawa; A.K. Rustgi K.D. Grugan; C.G. Miller; Y. Yao; C.Z. Michaylira; S. Ohashi; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; M. Han; H. Nakagawa; A.K. Rustgi K.D. Grugan; C.G. Miller; Y. Yao; C.Z. Michaylira; S. Ohashi; A.J. Klein-Szanto; J.A. Diehl; M. Herlyn; M. Han; H. Nakagawa; A.K. Rustgi Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion Proceedings of the National Academy of Sciences of the United States of America, 107, 24, 11026-11031 Proceedings of the National Academy of Sciences of the United States of America, 107, 24, 11026-11031 Proceedings of the National Academy of Sciences of the United States of America, 107, 24, 11026-11031 2010 英語 公開
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大橋 真也、武藤 学 大橋 真也、武藤 学 PDTのメカニズムーとくに食道癌細胞株におけるアポトーシスについて PDTのメカニズムーとくに食道癌細胞株におけるアポトーシスについて G.I.Reserach G.I.Reserach 2015/08 共著 公開
廣橋研志郎、大橋 真也、武藤 学 廣橋研志郎、大橋 真也、武藤 学 アルコール摂取と食道癌 アルコール摂取と食道癌 Medicina Medicina 2015/03 共著 公開
大橋真也、夏井坂光輝、長沼誠二、中川裕 大橋真也、夏井坂光輝、長沼誠二、中川裕 食道扁平上皮の分化と癌化はどこまでわかったか 食道扁平上皮の分化と癌化はどこまでわかったか 分子消化器病 先端医学社 分子消化器病 先端医学社 2012/12 日本語 公開
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基盤研究(C) 代表 EGFRシグナル阻害による細胞分化誘導を用いた食道癌に対する新しい治療法の開発 2013〜2015
基盤研究(C) 代表 EGFRシグナル阻害による細胞分化誘導を用いた食道癌に対する新しい治療法の開発 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(C) 代表 EGFRシグナル阻害による細胞分化誘導を用いた食道癌に対する新しい治療法の開発 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(C) 代表 アセトアルデヒド代謝機能改善に基づく食道発がん予防法の開発 2016/04/01〜2018/03/31
基盤研究(C) 代表 アセトアルデヒド代謝機能改善に基づく食道発がん予防法の開発 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 アセトアルデヒド代謝機能改善に基づく食道発がん予防法の開発 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(C) 代表 アセトアルデヒド代謝機能改善に基づく食道発がん予防法の開発 (平成30年度分) 2018/04/01〜2019/03/31