河口 浩介

最終更新日時: 2019/06/26 16:38:42

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氏名(漢字/フリガナ/アルファベット表記)
河口 浩介/カワグチ コウスケ/Kawaguchi, Kosuke
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/外科(乳腺外科)/助教
連絡先電話番号
種別 番号
職場 0757513660
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
ORCID ID
https://orcid.org/0000-0002-3161-7981
researchmap URL
https://researchmap.jp/7000024616
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M Alteration of specific cytokine expression patterns in patients with breast cancer. Alteration of specific cytokine expression patterns in patients with breast cancer. Alteration of specific cytokine expression patterns in patients with breast cancer. Scientific reports, 9, 1, 2924 Scientific reports, 9, 1, 2924 Scientific reports, 9, 1, 2924 2019/02 公開
Suzuki E, Sugimoto M, Kawaguchi K, Pu F, Uozumi R, Yamaguchi A, Nishie M, Tsuda M, Kotake T, Morita S, Toi M Suzuki E, Sugimoto M, Kawaguchi K, Pu F, Uozumi R, Yamaguchi A, Nishie M, Tsuda M, Kotake T, Morita S, Toi M Suzuki E, Sugimoto M, Kawaguchi K, Pu F, Uozumi R, Yamaguchi A, Nishie M, Tsuda M, Kotake T, Morita S, Toi M Gene expression profile of peripheral blood mononuclear cells may contribute to the identification and immunological classification of breast cancer patients. Gene expression profile of peripheral blood mononuclear cells may contribute to the identification and immunological classification of breast cancer patients. Gene expression profile of peripheral blood mononuclear cells may contribute to the identification and immunological classification of breast cancer patients. Breast cancer (Tokyo, Japan) Breast cancer (Tokyo, Japan) Breast cancer (Tokyo, Japan) 2018/10 公開
Yukiko Fukui, Masahiro Kawashima, Kosuke Kawaguchi, Megumi Takeuchi, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Masako Kataoka, Shotaro Kanao, Yuji Nakamoto, Kimiko Hirata, Michio Yoshimura, Katsuhiro Yoshikawa, Hiroshi Ishiguro, Masakazu Toi Yukiko Fukui, Masahiro Kawashima, Kosuke Kawaguchi, Megumi Takeuchi, Masahiro Hirata, Tatsuki R. Kataoka, Takaki Sakurai, Masako Kataoka, Shotaro Kanao, Yuji Nakamoto, Kimiko Hirata, Michio Yoshimura, Katsuhiro Yoshikawa, Hiroshi Ishiguro, Masakazu Toi Granulocyte-colony-stimulating factor-producing metaplastic carcinoma of the breast with significant elevation of serum interleukin-17 and vascular endothelial growth factor levels Granulocyte-colony-stimulating factor-producing metaplastic carcinoma of the breast with significant elevation of serum interleukin-17 and vascular endothelial growth factor levels Granulocyte-colony-stimulating factor-producing metaplastic carcinoma of the breast with significant elevation of serum interleukin-17 and vascular endothelial growth factor levels International Cancer Conference Journal, 7, 3, 107-113 International Cancer Conference Journal, 7, 3, 107-113 International Cancer Conference Journal, 7, 3, 107-113 2018/07 英語 研究論文(学術雑誌) 公開
Joao Incio, Jennifer A. Ligibel, Daniel T. McManus, Priya Suboj, Keehoon Jung, Kosuke Kawaguchi, Matthias Pinter, Suboj Babykutty, Shan M. Chin, Trupti D. Vardam, Yuhui Huang, Nuh N. Rahbari, Sylvie Roberge, Dannie Wang, Igor L. Gomes-Santos, Stefan B. Puchner, Christopher L. Schlett, Udo Hoffmman, Marek Ancukiewicz, Sara M. Tolaney, Ian E. Krop, Dan G. Duda, Yves Boucher, Dai Fukumura, Rakesh K. Jain Joao Incio, Jennifer A. Ligibel, Daniel T. McManus, Priya Suboj, Keehoon Jung, Kosuke Kawaguchi, Matthias Pinter, Suboj Babykutty, Shan M. Chin, Trupti D. Vardam, Yuhui Huang, Nuh N. Rahbari, Sylvie Roberge, Dannie Wang, Igor L. Gomes-Santos, Stefan B. Puchner, Christopher L. Schlett, Udo Hoffmman, Marek Ancukiewicz, Sara M. Tolaney, Ian E. Krop, Dan G. Duda, Yves Boucher, Dai Fukumura, Rakesh K. Jain Joao Incio, Jennifer A. Ligibel, Daniel T. McManus, Priya Suboj, Keehoon Jung, Kosuke Kawaguchi, Matthias Pinter, Suboj Babykutty, Shan M. Chin, Trupti D. Vardam, Yuhui Huang, Nuh N. Rahbari, Sylvie Roberge, Dannie Wang, Igor L. Gomes-Santos, Stefan B. Puchner, Christopher L. Schlett, Udo Hoffmman, Marek Ancukiewicz, Sara M. Tolaney, Ian E. Krop, Dan G. Duda, Yves Boucher, Dai Fukumura, Rakesh K. Jain Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 Science Translational Medicine, 10, 432, eaag0945 Science Translational Medicine, 10, 432, eaag0945 Science Translational Medicine, 10, 432, eaag0945 2018/03 公開
Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D Targeting CXCR4-dependent immunosuppressive Ly6C<sup>low</sup> monocytes improves antiangiogenic therapy in colorectal cancer. Targeting CXCR4-dependent immunosuppressive Ly6C<sup>low</sup> monocytes improves antiangiogenic therapy in colorectal cancer. Targeting CXCR4-dependent immunosuppressive Ly6C<sup>low</sup> monocytes improves antiangiogenic therapy in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America, 114, 39, 10455-10460 Proceedings of the National Academy of Sciences of the United States of America, 114, 39, 10455-10460 Proceedings of the National Academy of Sciences of the United States of America, 114, 39, 10455-10460 2017/09 公開
Kawaguchi K, Suzuki E, Yamaguchi A, Yamamoto M, Morita S, Toi M. Kawaguchi K, Suzuki E, Yamaguchi A, Yamamoto M, Morita S, Toi M. Kawaguchi K, Suzuki E, Yamaguchi A, Yamamoto M, Morita S, Toi M. Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer Breast Cancer, 24, 1, 111-120 Breast Cancer, 24, 1, 111-120 Breast Cancer, 24, 1, 111-120 2017 公開
Kawaguchi K, Suzuki E, Nishie M, Kii I, Kataoka T.R, Hirata M, Inoue M, Pu F, Iwaisako K, Tsuda M, Yamaguchi A, Haga H, Hagiwara M, Toi M. Kawaguchi K, Suzuki E, Nishie M, Kii I, Kataoka T.R, Hirata M, Inoue M, Pu F, Iwaisako K, Tsuda M, Yamaguchi A, Haga H, Hagiwara M, Toi M. Kawaguchi K, Suzuki E, Nishie M, Kii I, Kataoka T.R, Hirata M, Inoue M, Pu F, Iwaisako K, Tsuda M, Yamaguchi A, Haga H, Hagiwara M, Toi M. Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity Cancer Immunology, Immunotherapy, 1-12 Cancer Immunology, Immunotherapy, 1-12 Cancer Immunology, Immunotherapy, 1-12 2017 公開
Uehiro N, Sato F, Pu F, Tanaka S, Kawashima M, Kawaguchi K, Sugimoto M, Saji S, Toi M. Uehiro N, Sato F, Pu F, Tanaka S, Kawashima M, Kawaguchi K, Sugimoto M, Saji S, Toi M. Uehiro N, Sato F, Pu F, Tanaka S, Kawashima M, Kawaguchi K, Sugimoto M, Saji S, Toi M. Circulating cell-free DNA-based epigenetic assay can detect early breast cancer Circulating cell-free DNA-based epigenetic assay can detect early breast cancer Circulating cell-free DNA-based epigenetic assay can detect early breast cancer Breast Cancer Research, 18, 1 Breast Cancer Research, 18, 1 Breast Cancer Research, 18, 1 2016 公開
Suzuki E, Kataoka T.R, Hirata M, Kawaguchi K, Nishie M, Haga H, Toi M. Suzuki E, Kataoka T.R, Hirata M, Kawaguchi K, Nishie M, Haga H, Toi M. Suzuki E, Kataoka T.R, Hirata M, Kawaguchi K, Nishie M, Haga H, Toi M. Trogocytosis-mediated expression of HER2 on immune cells may be associated with a pathological complete response to trastuzumab-based primary systemic therapy in HER2-overexpressing breast cancer patients Trogocytosis-mediated expression of HER2 on immune cells may be associated with a pathological complete response to trastuzumab-based primary systemic therapy in HER2-overexpressing breast cancer patients Trogocytosis-mediated expression of HER2 on immune cells may be associated with a pathological complete response to trastuzumab-based primary systemic therapy in HER2-overexpressing breast cancer patients BMC Cancer, 15, 1 BMC Cancer, 15, 1 BMC Cancer, 15, 1 2015 公開
Tsuyuki, S. Yamaguchi, A. Kawata, Y. Kawaguchi, K. Tsuyuki, S. Yamaguchi, A. Kawata, Y. Kawaguchi, K. Assessing the effects of neoadjuvant chemotherapy on lymphatic pathways to sentinel lymph nodes in cases of breast cancer: Usefulness of the indocyanine green-fluorescence method Assessing the effects of neoadjuvant chemotherapy on lymphatic pathways to sentinel lymph nodes in cases of breast cancer: Usefulness of the indocyanine green-fluorescence method Assessing the effects of neoadjuvant chemotherapy on lymphatic pathways to sentinel lymph nodes in cases of breast cancer: Usefulness of the indocyanine green-fluorescence method Breast, 24, 298-301 Breast, 24, 298-301 Breast, 24, 298-301 2015 英語 研究論文(学術雑誌) 公開
Ishiguro H, Kawaguchi K, Nishimura T, Toi M. Ishiguro H, Kawaguchi K, Nishimura T, Toi M. Ishiguro H, Kawaguchi K, Nishimura T, Toi M. Antipsychotics-containing regimen as an alternative to standard antiemetics for delayed nausea induced by highly emetogenic chemotherapy Antipsychotics-containing regimen as an alternative to standard antiemetics for delayed nausea induced by highly emetogenic chemotherapy Antipsychotics-containing regimen as an alternative to standard antiemetics for delayed nausea induced by highly emetogenic chemotherapy Journal of Clinical Oncology, 31, 10, 1377-1378 Journal of Clinical Oncology, 31, 10, 1377-1378 Journal of Clinical Oncology, 31, 10, 1377-1378 2013 公開
Tsuyuki S, Kawaguchi K, Kawata Y, Yamaguchi A, Kanazawa A, Sugitatsu M, Kono Y. Tsuyuki S, Kawaguchi K, Kawata Y, Yamaguchi A, Kanazawa A, Sugitatsu M, Kono Y. Tsuyuki S, Kawaguchi K, Kawata Y, Yamaguchi A, Kanazawa A, Sugitatsu M, Kono Y. Usefulness of antimycotic agents (itraconazole) in chemotherapy-induced mucositis of breast cancer patients Usefulness of antimycotic agents (itraconazole) in chemotherapy-induced mucositis of breast cancer patients Usefulness of antimycotic agents (itraconazole) in chemotherapy-induced mucositis of breast cancer patients Japanese Journal of Cancer and Chemotherapy, 39, 9, 1369-1373 Japanese Journal of Cancer and Chemotherapy, 39, 9, 1369-1373 Japanese Journal of Cancer and Chemotherapy, 39, 9, 1369-1373 2012 公開
Kawaguchi K, Ishiguro H, Morita S, Nakamura S, Ohno S, Masuda N, Iwata H, Aogi K, Kuroi K, Toi M. Kawaguchi K, Ishiguro H, Morita S, Nakamura S, Ohno S, Masuda N, Iwata H, Aogi K, Kuroi K, Toi M. Kawaguchi K, Ishiguro H, Morita S, Nakamura S, Ohno S, Masuda N, Iwata H, Aogi K, Kuroi K, Toi M. Correlation between docetaxel-induced skin toxicity and the use of steroids and H 2 blockers: A multi-institution survey Correlation between docetaxel-induced skin toxicity and the use of steroids and H 2 blockers: A multi-institution survey Correlation between docetaxel-induced skin toxicity and the use of steroids and H 2 blockers: A multi-institution survey Breast Cancer Research and Treatment, 130, 2, 627-634 Breast Cancer Research and Treatment, 130, 2, 627-634 Breast Cancer Research and Treatment, 130, 2, 627-634 2011 公開

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講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
Analysis of tumor infiltrating lymphocytes in HER2 positive primary breast cancer with neoadjuvant Lapatinib and Trastuzumab: The NeoLath study (JBCRG-16) Analysis of tumor infiltrating lymphocytes in HER2 positive primary breast cancer with neoadjuvant Lapatinib and Trastuzumab: The NeoLath study (JBCRG-16) Analysis of tumor infiltrating lymphocytes in HER2 positive primary breast cancer with neoadjuvant Lapatinib and Trastuzumab: The NeoLath study (JBCRG-16) 米国臨床腫瘍学会 米国臨床腫瘍学会 American Society of Clinical Oncology annual meeting 2016 2016/06 英語 ポスター発表 公開
Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis and its correlation with indoleamine 2,3-dioxygenase in breast cancer Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis and its correlation with indoleamine 2,3-dioxygenase in breast cancer Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis and its correlation with indoleamine 2,3-dioxygenase in breast cancer 欧州臨床腫瘍学会アジア会議 欧州臨床腫瘍学会アジア会議 European Society for Medical Oncology ( ESMO) Asia 2015/12 英語 ポスター発表 公開
Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis in breast cancer and its negative association with treatment outcome Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis in breast cancer and its negative association with treatment outcome Upregulation of the interleukin 17/granulocyte-colony stimulating factor/fibroblast growth factor axis in breast cancer and its negative association with treatment outcome 2015 サンアントニオ乳癌学会議 2015 サンアントニオ乳癌学会議 2015 San Antonio Breast Cancer Symposium 2015/12 英語 ポスター発表 公開
Monocyte-expressed neuropilin-1 underlies anti-HER2 antibody-mediated tumoricidal activity in breast cancer Monocyte-expressed neuropilin-1 underlies anti-HER2 antibody-mediated tumoricidal activity in breast cancer Monocyte-expressed neuropilin-1 underlies anti-HER2 antibody-mediated tumoricidal activity in breast cancer he 2nd IFOM-Kyoto University Joint Symposium he 2nd IFOM-Kyoto University Joint Symposium he 2nd IFOM-Kyoto University Joint Symposium 2015/10 英語 ポスター発表 公開
Immune signatures may differ between early operable breast cancer and metastatic breast cancer patients Immune signatures may differ between early operable breast cancer and metastatic breast cancer patients Immune signatures may differ between early operable breast cancer and metastatic breast cancer patients 日本臨床腫瘍学会 日本臨床腫瘍学会 The Japanese Society of Medical Oncology Annual Meeting. 2015 2015/10 英語 シンポジウム・ワークショップパネル(公募) 公開
Knockdown of neuropilin-1 in monocytes impaired lymphocyte migration and anti-tumor activity in a humanized mouse model Knockdown of neuropilin-1 in monocytes impaired lymphocyte migration and anti-tumor activity in a humanized mouse model Knockdown of neuropilin-1 in monocytes impaired lymphocyte migration and anti-tumor activity in a humanized mouse model 米国癌学会 米国癌学会 American Association for Cancer Research Annual Meeting (AACR) 2015/04 英語 ポスター発表 公開
High neuropilin-1 expression on monocytes is positively associated with trastuzumab-mediated antibody-dependent cellular cytotoxicity of the HER2-overexpressing breast cancer cell line High neuropilin-1 expression on monocytes is positively associated with trastuzumab-mediated antibody-dependent cellular cytotoxicity of the HER2-overexpressing breast cancer cell line High neuropilin-1 expression on monocytes is positively associated with trastuzumab-mediated antibody-dependent cellular cytotoxicity of the HER2-overexpressing breast cancer cell line 米国癌学会 米国癌学会 American Association for Cancer Research Annual Meeting Annual Meeting (AACR) 2014/04 英語 ポスター発表 公開
Neuropilin-1 high monocytes play an important role in trastuzumab-mediated antibody-dependent cellular cytotoxicity in HER2-positive breast cancer cell lines Neuropilin-1 high monocytes play an important role in trastuzumab-mediated antibody-dependent cellular cytotoxicity in HER2-positive breast cancer cell lines Neuropilin-1 high monocytes play an important role in trastuzumab-mediated antibody-dependent cellular cytotoxicity in HER2-positive breast cancer cell lines 米国癌学会 米国癌学会 American Association for Cancer Research Annual Meeting (AACR) 2013/04 英語 ポスター発表 公開
Usefulness of an original self-completed questionnaire for screening of cancer-related mental disorder in patients with newly diagnosed early breast cancer Usefulness of an original self-completed questionnaire for screening of cancer-related mental disorder in patients with newly diagnosed early breast cancer Usefulness of an original self-completed questionnaire for screening of cancer-related mental disorder in patients with newly diagnosed early breast cancer 米国臨床腫瘍学会 乳癌シンポジウム 米国臨床腫瘍学会 乳癌シンポジウム American Society of Clinical Oncology (ASCO) Breast Cancer Symposium 2011/09 英語 ポスター発表 公開
Correlation between docetaxel-induced skin toxicity and the use of steroids and H2 blockers Correlation between docetaxel-induced skin toxicity and the use of steroids and H2 blockers Correlation between docetaxel-induced skin toxicity and the use of steroids and H2 blockers 米国臨床腫瘍学会 米国臨床腫瘍学会 American Society of Clinical Oncology (ASCO) Annual Meeting 2009/05 英語 シンポジウム・ワークショップパネル(指名) 公開
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