松澤 秀一

最終更新日時: 2019/06/24 16:07:34

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氏名(漢字/フリガナ/アルファベット表記)
松澤 秀一/マツザワ シユウイチ/Matsuzawa, Shuichi
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/内科(脳神経内科)/特定准教授
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
理学修士 北海道大学
博士(理学) 北海道大学
researchmap URL
https://researchmap.jp/7000015430
研究概要
(日本語)
神経変性疾患をターゲットとした創薬開発
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Jiang TX, Zou JB, Zhu QQ, Liu CH, Wang GF, Du TT, Luo ZY, Guo F, Zhou LM, Liu JJ, Zhang W, Shu YS, Yu L, Li P, Ronai ZA, Matsuzawa SI, Goldberg AL, Qiu XB Jiang TX, Zou JB, Zhu QQ, Liu CH, Wang GF, Du TT, Luo ZY, Guo F, Zhou LM, Liu JJ, Zhang W, Shu YS, Yu L, Li P, Ronai ZA, Matsuzawa SI, Goldberg AL, Qiu XB Jiang TX, Zou JB, Zhu QQ, Liu CH, Wang GF, Du TT, Luo ZY, Guo F, Zhou LM, Liu JJ, Zhang W, Shu YS, Yu L, Li P, Ronai ZA, Matsuzawa SI, Goldberg AL, Qiu XB SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation. SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation. SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation. Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America 2019/06 公開
Sanchez M, Xia Z, Rico-Bautista E, Cao X, Cuddy M, Castro DJ, Correa RG, Chen L, Yu J, Bobkov A, Ruvolo V, Andreeff M, Oshima RG, Matsuzawa SI, Reed JC, Zhang XK, Hansel D, Wolf DA, Dawson MI Sanchez M, Xia Z, Rico-Bautista E, Cao X, Cuddy M, Castro DJ, Correa RG, Chen L, Yu J, Bobkov A, Ruvolo V, Andreeff M, Oshima RG, Matsuzawa SI, Reed JC, Zhang XK, Hansel D, Wolf DA, Dawson MI Sanchez M, Xia Z, Rico-Bautista E, Cao X, Cuddy M, Castro DJ, Correa RG, Chen L, Yu J, Bobkov A, Ruvolo V, Andreeff M, Oshima RG, Matsuzawa SI, Reed JC, Zhang XK, Hansel D, Wolf DA, Dawson MI Oxidized analogs of Di(1<i>H</i>-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity. Oxidized analogs of Di(1<i>H</i>-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity. Oxidized analogs of Di(1<i>H</i>-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity. Oncotarget, 9, 38, 25057-25074 Oncotarget, 9, 38, 25057-25074 Oncotarget, 9, 38, 25057-25074 2018/05 公開
Yanagi T, Nagai K, Shimizu H, Matsuzawa SI Yanagi T, Nagai K, Shimizu H, Matsuzawa SI Yanagi T, Nagai K, Shimizu H, Matsuzawa SI Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression. Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression. Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression. Oncotarget, 8, 40, 68448-68459 Oncotarget, 8, 40, 68448-68459 Oncotarget, 8, 40, 68448-68459 2017/09 公開
Joo E, Fukushima T, Harada N, Reed JC, Matsuzawa SI, Inagaki N Joo E, Fukushima T, Harada N, Reed JC, Matsuzawa SI, Inagaki N Joo E, Fukushima T, Harada N, Reed JC, Matsuzawa SI, Inagaki N Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity. Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity. Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity. Scientific reports, 6, 35983 Scientific reports, 6, 35983 Scientific reports, 6, 35983 2016/10 公開
Welsh K, Milutinovic S, Ardecky RJ, Gonzalez-Lopez M, Ganji SR, Teriete P, Finlay D, Riedl S, Matsuzawa S, Pinilla C, Houghten R, Vuori K, Reed JC, Cosford ND Welsh K, Milutinovic S, Ardecky RJ, Gonzalez-Lopez M, Ganji SR, Teriete P, Finlay D, Riedl S, Matsuzawa S, Pinilla C, Houghten R, Vuori K, Reed JC, Cosford ND Welsh K, Milutinovic S, Ardecky RJ, Gonzalez-Lopez M, Ganji SR, Teriete P, Finlay D, Riedl S, Matsuzawa S, Pinilla C, Houghten R, Vuori K, Reed JC, Cosford ND Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis. Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis. Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis. PloS one, 11, 9, e0161952 PloS one, 11, 9, e0161952 PloS one, 11, 9, e0161952 2016/09 公開
Godoi PH, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa S, Reed JC Godoi PH, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa S, Reed JC Godoi PH, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa S, Reed JC Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins. Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins. Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins. The Journal of biological chemistry, 291, 27, 14072-14084 The Journal of biological chemistry, 291, 27, 14072-14084 The Journal of biological chemistry, 291, 27, 14072-14084 2016/07 公開
Yanagi T, Tachikawa K, Wilkie-Grantham R, Hishiki A, Nagai K, Toyonaga E, Chivukula P, Matsuzawa S Yanagi T, Tachikawa K, Wilkie-Grantham R, Hishiki A, Nagai K, Toyonaga E, Chivukula P, Matsuzawa S Yanagi T, Tachikawa K, Wilkie-Grantham R, Hishiki A, Nagai K, Toyonaga E, Chivukula P, Matsuzawa S Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth. Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth. Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth. Molecular therapy. Nucleic acids, 5, 6, e327 Molecular therapy. Nucleic acids, 5, 6, e327 Molecular therapy. Nucleic acids, 5, 6, e327 2016/06 公開
Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC Milutinovic S, Kashyap AK, Yanagi T, Wimer C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, Diaz PW, Matsuzawa S, Horowitz M, Horowitz L, Bhatt RR, Reed JC Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death. Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death. Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death. Molecular cancer therapeutics, 15, 1, 114-124 Molecular cancer therapeutics, 15, 1, 114-124 Molecular cancer therapeutics, 15, 1, 114-124 2016/01 公開
Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA Milutinovic S, Heynen-Genel S, Chao E, Dewing A, Solano R, Milan L, Barron N, He M, Diaz PW, Matsuzawa S, Reed JC, Hassig CA Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML). Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML). Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML). PloS one, 11, 3, e0152692 PloS one, 11, 3, e0152692 PloS one, 11, 3, e0152692 2016 公開
Rong J, Pass I, Diaz PW, Ngo TA, Sauer M, Magnuson G, Zeng FY, Hassig CA, Jackson MR, Cosford ND, Matsuzawa S, Reed JC Rong J, Pass I, Diaz PW, Ngo TA, Sauer M, Magnuson G, Zeng FY, Hassig CA, Jackson MR, Cosford ND, Matsuzawa S, Reed JC Rong J, Pass I, Diaz PW, Ngo TA, Sauer M, Magnuson G, Zeng FY, Hassig CA, Jackson MR, Cosford ND, Matsuzawa S, Reed JC Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1. Journal of biomolecular screening, 20, 10, 1232-1245 Journal of biomolecular screening, 20, 10, 1232-1245 Journal of biomolecular screening, 20, 10, 1232-1245 2015/12 公開
Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC ATG4B (Autophagin-1) phosphorylation modulates autophagy. ATG4B (Autophagin-1) phosphorylation modulates autophagy. ATG4B (Autophagin-1) phosphorylation modulates autophagy. The Journal of biological chemistry, 290, 44, 26549-26561 The Journal of biological chemistry, 290, 44, 26549-26561 The Journal of biological chemistry, 290, 44, 26549-26561 2015/10 公開
Qiao S, Dennis M, Song X, Vadysirisack DD, Salunke D, Nash Z, Yang Z, Liesa M, Yoshioka J, Matsuzawa S, Shirihai OS, Lee RT, Reed JC, Ellisen LW Qiao S, Dennis M, Song X, Vadysirisack DD, Salunke D, Nash Z, Yang Z, Liesa M, Yoshioka J, Matsuzawa S, Shirihai OS, Lee RT, Reed JC, Ellisen LW Qiao S, Dennis M, Song X, Vadysirisack DD, Salunke D, Nash Z, Yang Z, Liesa M, Yoshioka J, Matsuzawa S, Shirihai OS, Lee RT, Reed JC, Ellisen LW A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity. Nature communications, 6, 7014 Nature communications, 6, 7014 Nature communications, 6, 7014 2015/04 公開
D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, Reed JC D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, Reed JC D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, Reed JC Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PloS one, 10, 6, e0130635 PloS one, 10, 6, e0130635 PloS one, 10, 6, e0130635 2015 公開
Yanagi T, Shi R, Aza-Blanc P, Reed JC, Matsuzawa S Yanagi T, Shi R, Aza-Blanc P, Reed JC, Matsuzawa S Yanagi T, Shi R, Aza-Blanc P, Reed JC, Matsuzawa S PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PCTAIRE1-knockdown sensitizes cancer cells to TNF family cytokines. PloS one, 10, 3, e0119404 PloS one, 10, 3, e0119404 PloS one, 10, 3, e0119404 2015 公開
Yanagi T, Matsuzawa S Yanagi T, Matsuzawa S Yanagi T, Matsuzawa S PCTAIRE1/PCTK1/CDK16: a new oncotarget? PCTAIRE1/PCTK1/CDK16: a new oncotarget? PCTAIRE1/PCTK1/CDK16: a new oncotarget? Cell cycle (Georgetown, Tex.), 14, 4, 463-464 Cell cycle (Georgetown, Tex.), 14, 4, 463-464 Cell cycle (Georgetown, Tex.), 14, 4, 463-464 2015 公開
Yanagi T, Krajewska M, Matsuzawa S, Reed JC Yanagi T, Krajewska M, Matsuzawa S, Reed JC Yanagi T, Krajewska M, Matsuzawa S, Reed JC PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. Cancer research, 74, 20, 5795-5807 Cancer research, 74, 20, 5795-5807 Cancer research, 74, 20, 5795-5807 2014/10 公開
Yanagi T, Reed JC, Matsuzawa S Yanagi T, Reed JC, Matsuzawa S Yanagi T, Reed JC, Matsuzawa S PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma. PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma. PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma. Oncoscience, 1, 10, 624-633 Oncoscience, 1, 10, 624-633 Oncoscience, 1, 10, 624-633 2014 公開
Gerlic M, Faustin B, Postigo A, Yu EC, Proell M, Gombosuren N, Krajewska M, Flynn R, Croft M, Way M, Satterthwait A, Liddington RC, Salek-Ardakani S, Matsuzawa S, Reed JC Gerlic M, Faustin B, Postigo A, Yu EC, Proell M, Gombosuren N, Krajewska M, Flynn R, Croft M, Way M, Satterthwait A, Liddington RC, Salek-Ardakani S, Matsuzawa S, Reed JC Gerlic M, Faustin B, Postigo A, Yu EC, Proell M, Gombosuren N, Krajewska M, Flynn R, Croft M, Way M, Satterthwait A, Liddington RC, Salek-Ardakani S, Matsuzawa S, Reed JC Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation. Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation. Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America, 110, 19, 7808-7813 Proceedings of the National Academy of Sciences of the United States of America, 110, 19, 7808-7813 Proceedings of the National Academy of Sciences of the United States of America, 110, 19, 7808-7813 2013/05 公開
Wilkie-Grantham RP, Matsuzawa S, Reed JC Wilkie-Grantham RP, Matsuzawa S, Reed JC Wilkie-Grantham RP, Matsuzawa S, Reed JC Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein. Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein. Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein. The Journal of biological chemistry, 288, 18, 12777-12790 The Journal of biological chemistry, 288, 18, 12777-12790 The Journal of biological chemistry, 288, 18, 12777-12790 2013/05 公開
Benosman S, Ravanan P, Correa RG, Hou YC, Yu M, Gulen MF, Li X, Thomas J, Cuddy M, Matsuzawa Y, Sano R, Diaz P, Matsuzawa S, Reed JC Benosman S, Ravanan P, Correa RG, Hou YC, Yu M, Gulen MF, Li X, Thomas J, Cuddy M, Matsuzawa Y, Sano R, Diaz P, Matsuzawa S, Reed JC Benosman S, Ravanan P, Correa RG, Hou YC, Yu M, Gulen MF, Li X, Thomas J, Cuddy M, Matsuzawa Y, Sano R, Diaz P, Matsuzawa S, Reed JC Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling. Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling. Interleukin-1 receptor-associated kinase-2 (IRAK2) is a critical mediator of endoplasmic reticulum (ER) stress signaling. PloS one, 8, 5, e64256 PloS one, 8, 5, e64256 PloS one, 8, 5, e64256 2013 公開
Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy. Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy. Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy. Genes & development, 26, 10, 1041-1054 Genes & development, 26, 10, 1041-1054 Genes & development, 26, 10, 1041-1054 2012/05 公開
Madiraju C, Welsh K, Cuddy MP, Godoi PH, Pass I, Ngo T, Vasile S, Sergienko EA, Diaz P, Matsuzawa S, Reed JC Madiraju C, Welsh K, Cuddy MP, Godoi PH, Pass I, Ngo T, Vasile S, Sergienko EA, Diaz P, Matsuzawa S, Reed JC Madiraju C, Welsh K, Cuddy MP, Godoi PH, Pass I, Ngo T, Vasile S, Sergienko EA, Diaz P, Matsuzawa S, Reed JC TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors. TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors. TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors. Journal of biomolecular screening, 17, 2, 163-176 Journal of biomolecular screening, 17, 2, 163-176 Journal of biomolecular screening, 17, 2, 163-176 2012/02 公開
Ravanan P, Sano R, Talwar P, Ogasawara S, Matsuzawa S, Cuddy M, Singh SK, Rao GS, Kondaiah P, Reed JC Ravanan P, Sano R, Talwar P, Ogasawara S, Matsuzawa S, Cuddy M, Singh SK, Rao GS, Kondaiah P, Reed JC Ravanan P, Sano R, Talwar P, Ogasawara S, Matsuzawa S, Cuddy M, Singh SK, Rao GS, Kondaiah P, Reed JC Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines. Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines. Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines. Molecular cancer therapeutics, 10, 9, 1635-1643 Molecular cancer therapeutics, 10, 9, 1635-1643 Molecular cancer therapeutics, 10, 9, 1635-1643 2011/09 公開
Nagano Y, Fukushima T, Okemoto K, Tanaka K, Bowtell DD, Ronai Z, Reed JC, Matsuzawa S Nagano Y, Fukushima T, Okemoto K, Tanaka K, Bowtell DD, Ronai Z, Reed JC, Matsuzawa S Nagano Y, Fukushima T, Okemoto K, Tanaka K, Bowtell DD, Ronai Z, Reed JC, Matsuzawa S Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. Cell cycle (Georgetown, Tex.), 10, 15, 2592-2602 Cell cycle (Georgetown, Tex.), 10, 15, 2592-2602 Cell cycle (Georgetown, Tex.), 10, 15, 2592-2602 2011/08 公開
Yip KW, Cuddy M, Pinilla C, Giulanotti M, Heynen-Genel S, Matsuzawa S, Reed JC Yip KW, Cuddy M, Pinilla C, Giulanotti M, Heynen-Genel S, Matsuzawa S, Reed JC Yip KW, Cuddy M, Pinilla C, Giulanotti M, Heynen-Genel S, Matsuzawa S, Reed JC A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs). A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs). A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs). Journal of biomolecular screening, 16, 2, 251-258 Journal of biomolecular screening, 16, 2, 251-258 Journal of biomolecular screening, 16, 2, 251-258 2011/02 公開
Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B Gregory SM, Davis BK, West JA, Taxman DJ, Matsuzawa S, Reed JC, Ting JP, Damania B Discovery of a viral NLR homolog that inhibits the inflammasome. Discovery of a viral NLR homolog that inhibits the inflammasome. Discovery of a viral NLR homolog that inhibits the inflammasome. Science (New York, N.Y.), 331, 6015, 330-334 Science (New York, N.Y.), 331, 6015, 330-334 Science (New York, N.Y.), 331, 6015, 330-334 2011/01 公開
Ardecky R, Madiraj C, Matsuzawa S, Zou J, Ganji S, Pass I, Ngo TA, Pinkerton AB, Sergienko E, Su Y, Stonich D, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Matsuzawa Y, Wimer C, Diaz PW, Reed JC Ardecky R, Madiraj C, Matsuzawa S, Zou J, Ganji S, Pass I, Ngo TA, Pinkerton AB, Sergienko E, Su Y, Stonich D, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Matsuzawa Y, Wimer C, Diaz PW, Reed JC Ardecky R, Madiraj C, Matsuzawa S, Zou J, Ganji S, Pass I, Ngo TA, Pinkerton AB, Sergienko E, Su Y, Stonich D, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Matsuzawa Y, Wimer C, Diaz PW, Reed JC Selective UBC 13 Inhibitors Selective UBC 13 Inhibitors Selective UBC 13 Inhibitors 2010 公開
Bayón Y, Trinidad AG, de la Puerta ML, Del Carmen Rodríguez M, Bogetz J, Rojas A, De Pereda JM, Rahmouni S, Williams S, Matsuzawa S, Reed JC, Crespo MS, Mustelin T, Alonso A Bayón Y, Trinidad AG, de la Puerta ML, Del Carmen Rodríguez M, Bogetz J, Rojas A, De Pereda JM, Rahmouni S, Williams S, Matsuzawa S, Reed JC, Crespo MS, Mustelin T, Alonso A Bayón Y, Trinidad AG, de la Puerta ML, Del Carmen Rodríguez M, Bogetz J, Rojas A, De Pereda JM, Rahmouni S, Williams S, Matsuzawa S, Reed JC, Crespo MS, Mustelin T, Alonso A KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. The FEBS journal, 275, 15, 3900-3910 The FEBS journal, 275, 15, 3900-3910 The FEBS journal, 275, 15, 3900-3910 2008/08 公開
Gdynia G, Lehmann-Koch J, Sieber S, Tagscherer KE, Fassl A, Zentgraf H, Matsuzawa S, Reed JC, Roth W Gdynia G, Lehmann-Koch J, Sieber S, Tagscherer KE, Fassl A, Zentgraf H, Matsuzawa S, Reed JC, Roth W Gdynia G, Lehmann-Koch J, Sieber S, Tagscherer KE, Fassl A, Zentgraf H, Matsuzawa S, Reed JC, Roth W BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. Apoptosis : an international journal on programmed cell death, 13, 3, 437-447 Apoptosis : an international journal on programmed cell death, 13, 3, 437-447 Apoptosis : an international journal on programmed cell death, 13, 3, 437-447 2008/03 公開
Ishioka T, Katayama R, Kikuchi R, Nishimoto M, Takada S, Takada R, Matsuzawa S, Reed JC, Tsuruo T, Naito M Ishioka T, Katayama R, Kikuchi R, Nishimoto M, Takada S, Takada R, Matsuzawa S, Reed JC, Tsuruo T, Naito M Ishioka T, Katayama R, Kikuchi R, Nishimoto M, Takada S, Takada R, Matsuzawa S, Reed JC, Tsuruo T, Naito M Impairment of the ubiquitin-proteasome system by cellular FLIP. Impairment of the ubiquitin-proteasome system by cellular FLIP. Impairment of the ubiquitin-proteasome system by cellular FLIP. Genes to cells : devoted to molecular & cellular mechanisms, 12, 6, 735-744 Genes to cells : devoted to molecular & cellular mechanisms, 12, 6, 735-744 Genes to cells : devoted to molecular & cellular mechanisms, 12, 6, 735-744 2007/06 公開
Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, Xu C, Kress CL, Bailly-Maitre B, Li X, Osterman A, Matsuzawa S, Terskikh AV, Faustin B, Reed JC Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell, 129, 1, 45-56 Cell, 129, 1, 45-56 Cell, 129, 1, 45-56 2007/04 公開
Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, Ronai Z, Reed JC Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses. Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses. Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses. Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6371-6376 Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6371-6376 Proceedings of the National Academy of Sciences of the United States of America, 104, 15, 6371-6376 2007/04 公開
Matsuzawa S, Reed JC Matsuzawa S, Reed JC Matsuzawa S, Reed JC Yeast and mammalian two-hybrid systems for studying protein-protein interactions. Yeast and mammalian two-hybrid systems for studying protein-protein interactions. Yeast and mammalian two-hybrid systems for studying protein-protein interactions. Methods in molecular biology (Clifton, N.J.), 383, 215-225 Methods in molecular biology (Clifton, N.J.), 383, 215-225 Methods in molecular biology (Clifton, N.J.), 383, 215-225 2007 公開
Fujii R, Zhu C, Wen Y, Marusawa H, Bailly-Maitre B, Matsuzawa S, Zhang H, Kim Y, Bennett CF, Jiang W, Reed JC Fujii R, Zhu C, Wen Y, Marusawa H, Bailly-Maitre B, Matsuzawa S, Zhang H, Kim Y, Bennett CF, Jiang W, Reed JC Fujii R, Zhu C, Wen Y, Marusawa H, Bailly-Maitre B, Matsuzawa S, Zhang H, Kim Y, Bennett CF, Jiang W, Reed JC HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis. HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis. HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis. Cancer research, 66, 18, 9099-9107 Cancer research, 66, 18, 9099-9107 Cancer research, 66, 18, 9099-9107 2006/09 公開
Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa S Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa S Fukushima T, Zapata JM, Singha NC, Thomas M, Kress CL, Krajewska M, Krajewski S, Ronai Z, Reed JC, Matsuzawa S Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint. Immunity, 24, 1, 29-39 Immunity, 24, 1, 29-39 Immunity, 24, 1, 29-39 2006/01 公開
Matsuzawa S, Cuddy M, Fukushima T, Reed JC Matsuzawa S, Cuddy M, Fukushima T, Reed JC Matsuzawa S, Cuddy M, Fukushima T, Reed JC Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway. Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway. Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway. Proceedings of the National Academy of Sciences of the United States of America, 102, 42, 14982-14987 Proceedings of the National Academy of Sciences of the United States of America, 102, 42, 14982-14987 Proceedings of the National Academy of Sciences of the United States of America, 102, 42, 14982-14987 2005/10 公開
Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. The Journal of biological chemistry, 280, 40, 34278-34287 The Journal of biological chemistry, 280, 40, 34278-34287 The Journal of biological chemistry, 280, 40, 34278-34287 2005/10 公開
Krajewska M, Kim H, Kim C, Kang H, Welsh K, Matsuzawa S, Tsukamoto M, Thomas RG, Assa-Munt N, Piao Z, Suzuki K, Perucho M, Krajewski S, Reed JC Krajewska M, Kim H, Kim C, Kang H, Welsh K, Matsuzawa S, Tsukamoto M, Thomas RG, Assa-Munt N, Piao Z, Suzuki K, Perucho M, Krajewski S, Reed JC Krajewska M, Kim H, Kim C, Kang H, Welsh K, Matsuzawa S, Tsukamoto M, Thomas RG, Assa-Munt N, Piao Z, Suzuki K, Perucho M, Krajewski S, Reed JC Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers. Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers. Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers. Clinical cancer research : an official journal of the American Association for Cancer Research, 11, 15, 5451-5461 Clinical cancer research : an official journal of the American Association for Cancer Research, 11, 15, 5451-5461 Clinical cancer research : an official journal of the American Association for Cancer Research, 11, 15, 5451-5461 2005/08 公開
Naito M, Katayama R, Ishioka T, Suga A, Takubo K, Nanjo M, Hashimoto C, Taira M, Takada S, Takada R, Kitagawa M, Matsuzawa S, Reed JC, Tsuruo T Naito M, Katayama R, Ishioka T, Suga A, Takubo K, Nanjo M, Hashimoto C, Taira M, Takada S, Takada R, Kitagawa M, Matsuzawa S, Reed JC, Tsuruo T Naito M, Katayama R, Ishioka T, Suga A, Takubo K, Nanjo M, Hashimoto C, Taira M, Takada S, Takada R, Kitagawa M, Matsuzawa S, Reed JC, Tsuruo T Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling. Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling. Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling. Molecular and cellular biology, 24, 19, 8418-8427 Molecular and cellular biology, 24, 19, 8418-8427 Molecular and cellular biology, 24, 19, 8418-8427 2004/10 公開
Iwai A, Marusawa H, Matsuzawa S, Fukushima T, Hijikata M, Reed JC, Shimotohno K, Chiba T Iwai A, Marusawa H, Matsuzawa S, Fukushima T, Hijikata M, Reed JC, Shimotohno K, Chiba T Iwai A, Marusawa H, Matsuzawa S, Fukushima T, Hijikata M, Reed JC, Shimotohno K, Chiba T Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner. Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner. Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner. Oncogene, 23, 45, 7593-7600 Oncogene, 23, 45, 7593-7600 Oncogene, 23, 45, 7593-7600 2004/09 公開
Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, Marusawa H, Zou H, Armstrong R, Matsuzawa S, Salvesen GS, Reed JC, Altieri DC Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, Marusawa H, Zou H, Armstrong R, Matsuzawa S, Salvesen GS, Reed JC, Altieri DC Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, Marusawa H, Zou H, Armstrong R, Matsuzawa S, Salvesen GS, Reed JC, Altieri DC An IAP-IAP complex inhibits apoptosis. An IAP-IAP complex inhibits apoptosis. An IAP-IAP complex inhibits apoptosis. The Journal of biological chemistry, 279, 33, 34087-34090 The Journal of biological chemistry, 279, 33, 34087-34090 The Journal of biological chemistry, 279, 33, 34087-34090 2004/08 公開
Fanelli M, Fantozzi A, De Luca P, Caprodossi S, Matsuzawa S, Lazar MA, Pelicci PG, Minucci S Fanelli M, Fantozzi A, De Luca P, Caprodossi S, Matsuzawa S, Lazar MA, Pelicci PG, Minucci S Fanelli M, Fantozzi A, De Luca P, Caprodossi S, Matsuzawa S, Lazar MA, Pelicci PG, Minucci S The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome. The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome. The coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasome. The Journal of biological chemistry, 279, 7, 5374-5379 The Journal of biological chemistry, 279, 7, 5374-5379 The Journal of biological chemistry, 279, 7, 5374-5379 2004/02 公開
Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A, RIKEN GER Group, GSL Members Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A, RIKEN GER Group, GSL Members Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A, RIKEN GER Group, GSL Members Comparative analysis of apoptosis and inflammation genes of mice and humans. Comparative analysis of apoptosis and inflammation genes of mice and humans. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome research, 13, 6B, 1376-1388 Genome research, 13, 6B, 1376-1388 Genome research, 13, 6B, 1376-1388 2003/06 公開
Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I, Reed JC Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I, Reed JC Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I, Reed JC HBXIP functions as a cofactor of survivin in apoptosis suppression. HBXIP functions as a cofactor of survivin in apoptosis suppression. HBXIP functions as a cofactor of survivin in apoptosis suppression. The EMBO journal, 22, 11, 2729-2740 The EMBO journal, 22, 11, 2729-2740 The EMBO journal, 22, 11, 2729-2740 2003/06 公開
Matsuzawa S, Li C, Ni CZ, Takayama S, Reed JC, Ely KR Matsuzawa S, Li C, Ni CZ, Takayama S, Reed JC, Ely KR Matsuzawa S, Li C, Ni CZ, Takayama S, Reed JC, Ely KR Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). The Journal of biological chemistry, 278, 3, 1837-1840 The Journal of biological chemistry, 278, 3, 1837-1840 The Journal of biological chemistry, 278, 3, 1837-1840 2003/01 公開
Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton. Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton. Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton. The Biochemical journal, 364, Pt 3, 669-677 The Biochemical journal, 364, Pt 3, 669-677 The Biochemical journal, 364, Pt 3, 669-677 2002/06 公開

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