VANDENBON Alexis

最終更新日時: 2019/09/25 11:09:40

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氏名(漢字/フリガナ/アルファベット表記)
VANDENBON Alexis/バンデンボン アレクシス/Vandenbon, Alexis
所属部署・職名(部局/所属/講座等/職名)
ウイルス・再生医科学研究所/生命システム研究部門/講師
学部兼担
部局 所属 講座等 職名
国際高等教育院
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
M.S. Katholieke HogeschoolBrugge-Oostende
M.S. Ghent University
博士(生命科学) 東京大学
researchmap URL
https://researchmap.jp/alexisvdb
研究テーマ
(日本語)
エピジェネティクス・転写・転写後レベルにわたる遺伝子発現の制御機構の予測
(英語)
Prediction of regulatory mechanisms of gene expression at the epigenetic, transcriptional, and post-transcriptional level.
研究概要
(英語)
Biological data is often high-dimensional, and therefore difficult to process, visualize, and analyze. The goal of my research is the discovery of new insights in biological data using bioinformatics approaches. Recent projects include the prediction of new regulators from thousands of gene expression samples (RNA-seq), and understanding the timing of epigenetic modifications from ChIP-seq data. Currently, I am developing a bioinformatics method for finding interesting genes in single-cell RNA-seq data.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
バイオインフォマティクス Bioinformatics
システムゲノム科学 System genome science
エピジェネティクス Epigenetics
転写後調節 Transcriptional regulation
シングルセル解析 Single-cell analysis
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Hia F, Yang SF, Shichino Y, Yoshinaga M, Murakawa Y, Vandenbon A, Fukao A, Fujiwara T, Landthaler M, Natsume T, Adachi S, Iwasaki S, Takeuchi O Hia F, Yang SF, Shichino Y, Yoshinaga M, Murakawa Y, Vandenbon A, Fukao A, Fujiwara T, Landthaler M, Natsume T, Adachi S, Iwasaki S, Takeuchi O Hia F, Yang SF, Shichino Y, Yoshinaga M, Murakawa Y, Vandenbon A, Fukao A, Fujiwara T, Landthaler M, Natsume T, Adachi S, Iwasaki S, Takeuchi O Codon bias confers stability to human mRNAs. Codon bias confers stability to human mRNAs. Codon bias confers stability to human mRNAs. EMBO reports, e48220 EMBO reports, e48220 EMBO reports, e48220 2019/09 公開
Vandenbon A.*†, Kumagai Y.†, Lin M., Suzuki Y., Nakai K.* Vandenbon A.*†, Kumagai Y.†, Lin M., Suzuki Y., Nakai K.* Vandenbon A.*†, Kumagai Y.†, Lin M., Suzuki Y., Nakai K.* Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation Genome Biology, 19, 1, 138 Genome Biology, 19, 1, 138 Genome Biology, 19, 1, 138 2018/09 英語 研究論文(学術雑誌) 公開
Nakatsuka Y, Vandenbon A, Mino T, Yoshinaga M, Uehata T, Cui X, Sato A, Tsujimura T, Suzuki Y, Sato A, Handa T, Chin K, Sawa T, Hirai T, Takeuchi O Nakatsuka Y, Vandenbon A, Mino T, Yoshinaga M, Uehata T, Cui X, Sato A, Tsujimura T, Suzuki Y, Sato A, Handa T, Chin K, Sawa T, Hirai T, Takeuchi O Nakatsuka Y, Vandenbon A, Mino T, Yoshinaga M, Uehata T, Cui X, Sato A, Tsujimura T, Suzuki Y, Sato A, Handa T, Chin K, Sawa T, Hirai T, Takeuchi O Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia. Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia. Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia. Mucosal immunology Mucosal immunology Mucosal immunology 2018/04 公開
Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nature immunology, 18, 11, 1270 Nature immunology, 18, 11, 1270 Nature immunology, 18, 11, 1270 2017/10 公開
Yoshinaga M, Nakatsuka Y, Vandenbon A, Ori D, Uehata T, Tsujimura T, Suzuki Y, Mino T, Takeuchi O Yoshinaga M, Nakatsuka Y, Vandenbon A, Ori D, Uehata T, Tsujimura T, Suzuki Y, Mino T, Takeuchi O Yoshinaga M, Nakatsuka Y, Vandenbon A, Ori D, Uehata T, Tsujimura T, Suzuki Y, Mino T, Takeuchi O Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs. Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs. Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs. Cell reports, 19, 8, 1614-1630 Cell reports, 19, 8, 1614-1630 Cell reports, 19, 8, 1614-1630 2017/05 公開
Kadena M, Kumagai Y, Vandenbon A, Matsushima H, Fukamachi H, Maruta N, Kataoka H, Arimoto T, Morisaki H, Funatsu T, Kuwata H Kadena M, Kumagai Y, Vandenbon A, Matsushima H, Fukamachi H, Maruta N, Kataoka H, Arimoto T, Morisaki H, Funatsu T, Kuwata H Kadena M, Kumagai Y, Vandenbon A, Matsushima H, Fukamachi H, Maruta N, Kataoka H, Arimoto T, Morisaki H, Funatsu T, Kuwata H Microarray and gene co-expression analysis reveals that melatonin attenuates immune responses and modulates actin rearrangement in macrophages. Microarray and gene co-expression analysis reveals that melatonin attenuates immune responses and modulates actin rearrangement in macrophages. Microarray and gene co-expression analysis reveals that melatonin attenuates immune responses and modulates actin rearrangement in macrophages. Biochemical and biophysical research communications, 485, 2, 414-420 Biochemical and biophysical research communications, 485, 2, 414-420 Biochemical and biophysical research communications, 485, 2, 414-420 2017/04 公開
Matsushima H, Kumagai Y, Vandenbon A, Kataoka H, Kadena M, Fukamachi H, Arimoto T, Morisaki H, Fujiwara N, Okahashi N, Kuwata H Matsushima H, Kumagai Y, Vandenbon A, Kataoka H, Kadena M, Fukamachi H, Arimoto T, Morisaki H, Fujiwara N, Okahashi N, Kuwata H Matsushima H, Kumagai Y, Vandenbon A, Kataoka H, Kadena M, Fukamachi H, Arimoto T, Morisaki H, Fujiwara N, Okahashi N, Kuwata H Microarray analysis of macrophage response to infection with Streptococcus oralis reveals the immunosuppressive effect of hydrogen peroxide. Microarray analysis of macrophage response to infection with Streptococcus oralis reveals the immunosuppressive effect of hydrogen peroxide. Microarray analysis of macrophage response to infection with Streptococcus oralis reveals the immunosuppressive effect of hydrogen peroxide. Biochemical and biophysical research communications, 485, 2, 461-467 Biochemical and biophysical research communications, 485, 2, 461-467 Biochemical and biophysical research communications, 485, 2, 461-467 2017/04 公開
Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nature immunology, 18, 4, 474 Nature immunology, 18, 4, 474 Nature immunology, 18, 4, 474 2017/03 公開
Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M, Taniuchi I, Kohwi-Shigematsu T, Sakaguchi S Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment. Nature immunology, 18, 2, 173-183 Nature immunology, 18, 2, 173-183 Nature immunology, 18, 2, 173-183 2017/02 公開
López Y, Vandenbon A, Nose A, Nakai K López Y, Vandenbon A, Nose A, Nakai K López Y, Vandenbon A, Nose A, Nakai K Modeling the <i>cis</i>-regulatory modules of genes expressed in developmental stages of <i>Drosophila melanogaster</i>. Modeling the <i>cis</i>-regulatory modules of genes expressed in developmental stages of <i>Drosophila melanogaster</i>. Modeling the <i>cis</i>-regulatory modules of genes expressed in developmental stages of <i>Drosophila melanogaster</i>. PeerJ, 5, e3389 PeerJ, 5, e3389 PeerJ, 5, e3389 2017 公開
Nosirov B, Billaud J, Vandenbon A, Diez D, Wijaya E, Ishii KJ, Teraguchi S, Standley DM Nosirov B, Billaud J, Vandenbon A, Diez D, Wijaya E, Ishii KJ, Teraguchi S, Standley DM Nosirov B, Billaud J, Vandenbon A, Diez D, Wijaya E, Ishii KJ, Teraguchi S, Standley DM Mapping circulating serum miRNAs to their immune-related target mRNAs. Mapping circulating serum miRNAs to their immune-related target mRNAs. Mapping circulating serum miRNAs to their immune-related target mRNAs. Advances and applications in bioinformatics and chemistry : AABC, 10, 1-9 Advances and applications in bioinformatics and chemistry : AABC, 10, 1-9 Advances and applications in bioinformatics and chemistry : AABC, 10, 1-9 2017 公開
Kumagai Y, Vandenbon A, Teraguchi S, Akira S, Suzuki Y Kumagai Y, Vandenbon A, Teraguchi S, Akira S, Suzuki Y Kumagai Y, Vandenbon A, Teraguchi S, Akira S, Suzuki Y Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs. Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs. Genome-wide map of RNA degradation kinetics patterns in dendritic cells after LPS stimulation facilitates identification of primary sequence and secondary structure motifs in mRNAs. BMC genomics, 17, Suppl 13, 1032 BMC genomics, 17, Suppl 13, 1032 BMC genomics, 17, Suppl 13, 1032 2016/12 公開
Ikebuchi R, Teraguchi S, Vandenbon A, Honda T, Shand FH, Nakanishi Y, Watanabe T, Tomura M Ikebuchi R, Teraguchi S, Vandenbon A, Honda T, Shand FH, Nakanishi Y, Watanabe T, Tomura M Ikebuchi R, Teraguchi S, Vandenbon A, Honda T, Shand FH, Nakanishi Y, Watanabe T, Tomura M A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response. A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response. A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response. Scientific reports, 6, 35002 Scientific reports, 6, 35002 Scientific reports, 6, 35002 2016/10 公開
Vandenbon A, Dinh VH, Mikami N, Kitagawa Y, Teraguchi S, Ohkura N, Sakaguchi S Vandenbon A, Dinh VH, Mikami N, Kitagawa Y, Teraguchi S, Ohkura N, Sakaguchi S Vandenbon A, Dinh VH, Mikami N, Kitagawa Y, Teraguchi S, Ohkura N, Sakaguchi S Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system. Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system. Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system. Proceedings of the National Academy of Sciences of the United States of America, 113, 17, E2393-402 Proceedings of the National Academy of Sciences of the United States of America, 113, 17, E2393-402 Proceedings of the National Academy of Sciences of the United States of America, 113, 17, E2393-402 2016/04 公開
Mino T, Murakawa Y, Fukao A, Vandenbon A, Wessels HH, Ori D, Uehata T, Tartey S, Akira S, Suzuki Y, Vinuesa CG, Ohler U, Standley DM, Landthaler M, Fujiwara T, Takeuchi O Mino T, Murakawa Y, Fukao A, Vandenbon A, Wessels HH, Ori D, Uehata T, Tartey S, Akira S, Suzuki Y, Vinuesa CG, Ohler U, Standley DM, Landthaler M, Fujiwara T, Takeuchi O Mino T, Murakawa Y, Fukao A, Vandenbon A, Wessels HH, Ori D, Uehata T, Tartey S, Akira S, Suzuki Y, Vinuesa CG, Ohler U, Standley DM, Landthaler M, Fujiwara T, Takeuchi O Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms. Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms. Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms. Cell, 161, 5, 1058-1073 Cell, 161, 5, 1058-1073 Cell, 161, 5, 1058-1073 2015/05 公開
Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley DM, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii KJ Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley DM, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii KJ Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley DM, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii KJ Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen. Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen. Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen. Journal of immunology (Baltimore, Md. : 1950), 194, 6, 2673-2682 Journal of immunology (Baltimore, Md. : 1950), 194, 6, 2673-2682 Journal of immunology (Baltimore, Md. : 1950), 194, 6, 2673-2682 2015/03 公開
Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira S, Takeuchi O Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex. The EMBO journal, 33, 20, 2332-2348 The EMBO journal, 33, 20, 2332-2348 The EMBO journal, 33, 20, 2332-2348 2014/10 公開
Morikawa H, Ohkura N, Vandenbon A, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Standley DM, Date H, Sakaguchi S, FANTOM Consortium. Morikawa H, Ohkura N, Vandenbon A, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Standley DM, Date H, Sakaguchi S, FANTOM Consortium. Morikawa H, Ohkura N, Vandenbon A, Itoh M, Nagao-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Standley DM, Date H, Sakaguchi S, FANTOM Consortium. Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation. Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation. Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation. Proceedings of the National Academy of Sciences of the United States of America, 111, 14, 5289-5294 Proceedings of the National Academy of Sciences of the United States of America, 111, 14, 5289-5294 Proceedings of the National Academy of Sciences of the United States of America, 111, 14, 5289-5294 2014/04 公開
Vandenbon A, Teraguchi S, Takeuchi O, Suzuki Y, Standley DM Vandenbon A, Teraguchi S, Takeuchi O, Suzuki Y, Standley DM Vandenbon A, Teraguchi S, Takeuchi O, Suzuki Y, Standley DM Dynamics of enhancers in myeloid antigen presenting cells upon LPS stimulation. Dynamics of enhancers in myeloid antigen presenting cells upon LPS stimulation. Dynamics of enhancers in myeloid antigen presenting cells upon LPS stimulation. BMC genomics, 15 Suppl 10, S4 BMC genomics, 15 Suppl 10, S4 BMC genomics, 15 Suppl 10, S4 2014 公開
López Y, Vandenbon A, Nakai K López Y, Vandenbon A, Nakai K López Y, Vandenbon A, Nakai K A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. PloS one, 9, 8, e104342 PloS one, 9, 8, e104342 PloS one, 9, 8, e104342 2014 公開
Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira S Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira S Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira S Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation. Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation. Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation. Cell, 153, 5, 1036-1049 Cell, 153, 5, 1036-1049 Cell, 153, 5, 1036-1049 2013/05 公開
Vandenbon A, Kumagai Y, Teraguchi S, Amada KM, Akira S, Standley DM Vandenbon A, Kumagai Y, Teraguchi S, Amada KM, Akira S, Standley DM Vandenbon A, Kumagai Y, Teraguchi S, Amada KM, Akira S, Standley DM A Parzen window-based approach for the detection of locally enriched transcription factor binding sites. A Parzen window-based approach for the detection of locally enriched transcription factor binding sites. A Parzen window-based approach for the detection of locally enriched transcription factor binding sites. BMC bioinformatics, 14, 26 BMC bioinformatics, 14, 26 BMC bioinformatics, 14, 26 2013/01 公開
Maruyama K, Fukasaka M, Vandenbon A, Saitoh T, Kawasaki T, Kondo T, Yokoyama KK, Kidoya H, Takakura N, Standley D, Takeuchi O, Akira S Maruyama K, Fukasaka M, Vandenbon A, Saitoh T, Kawasaki T, Kondo T, Yokoyama KK, Kidoya H, Takakura N, Standley D, Takeuchi O, Akira S Maruyama K, Fukasaka M, Vandenbon A, Saitoh T, Kawasaki T, Kondo T, Yokoyama KK, Kidoya H, Takakura N, Standley D, Takeuchi O, Akira S The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation. The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation. The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation. Immunity, 37, 6, 1024-1036 Immunity, 37, 6, 1024-1036 Immunity, 37, 6, 1024-1036 2012/12 公開
Vandenbon A, Teraguchi S, Akira S, Takeda K, Standley DM Vandenbon A, Teraguchi S, Akira S, Takeda K, Standley DM Vandenbon A, Teraguchi S, Akira S, Takeda K, Standley DM Systems biology approaches to toll-like receptor signaling. Systems biology approaches to toll-like receptor signaling. Systems biology approaches to toll-like receptor signaling. Wiley interdisciplinary reviews. Systems biology and medicine, 4, 5, 497-507 Wiley interdisciplinary reviews. Systems biology and medicine, 4, 5, 497-507 Wiley interdisciplinary reviews. Systems biology and medicine, 4, 5, 497-507 2012/09 公開
Vandenbon A, Kumagai Y, Akira S, Standley DM Vandenbon A, Kumagai Y, Akira S, Standley DM Vandenbon A, Kumagai Y, Akira S, Standley DM A novel unbiased measure for motif co-occurrence predicts combinatorial regulation of transcription. A novel unbiased measure for motif co-occurrence predicts combinatorial regulation of transcription. A novel unbiased measure for motif co-occurrence predicts combinatorial regulation of transcription. BMC genomics, 13 Suppl 7, S11 BMC genomics, 13 Suppl 7, S11 BMC genomics, 13 Suppl 7, S11 2012 公開
Teraguchi S, Kumagai Y, Vandenbon A, Akira S, Standley DM Teraguchi S, Kumagai Y, Vandenbon A, Akira S, Standley DM Teraguchi S, Kumagai Y, Vandenbon A, Akira S, Standley DM Stochastic binary modeling of cells in continuous time as an alternative to biochemical reaction equations. Stochastic binary modeling of cells in continuous time as an alternative to biochemical reaction equations. Stochastic binary modeling of cells in continuous time as an alternative to biochemical reaction equations. Physical review. E, Statistical, nonlinear, and soft matter physics, 84, 6 Pt 1, 062903 Physical review. E, Statistical, nonlinear, and soft matter physics, 84, 6 Pt 1, 062903 Physical review. E, Statistical, nonlinear, and soft matter physics, 84, 6 Pt 1, 062903 2011/12 公開
Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18. IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18. IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18. Proceedings of the National Academy of Sciences of the United States of America, 107, 41, 17680-17685 Proceedings of the National Academy of Sciences of the United States of America, 107, 41, 17680-17685 Proceedings of the National Academy of Sciences of the United States of America, 107, 41, 17680-17685 2010/10 公開
Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nature immunology, 11, 10, 936-944 Nature immunology, 11, 10, 936-944 Nature immunology, 11, 10, 936-944 2010/10 公開
Vandenbon A, Nakai K Vandenbon A, Nakai K Vandenbon A, Nakai K Modeling tissue-specific structural patterns in human and mouse promoters. Modeling tissue-specific structural patterns in human and mouse promoters. Modeling tissue-specific structural patterns in human and mouse promoters. Nucleic acids research, 38, 1, 17-25 Nucleic acids research, 38, 1, 17-25 Nucleic acids research, 38, 1, 17-25 2010/01 公開
Vandenbon A, Miyamoto Y, Takimoto N, Kusakabe T, Nakai K Vandenbon A, Miyamoto Y, Takimoto N, Kusakabe T, Nakai K Vandenbon A, Miyamoto Y, Takimoto N, Kusakabe T, Nakai K Markov chain-based promoter structure modeling for tissue-specific expression pattern prediction. Markov chain-based promoter structure modeling for tissue-specific expression pattern prediction. Markov chain-based promoter structure modeling for tissue-specific expression pattern prediction. DNA research : an international journal for rapid publication of reports on genes and genomes, 15, 1, 3-11 DNA research : an international journal for rapid publication of reports on genes and genomes, 15, 1, 3-11 DNA research : an international journal for rapid publication of reports on genes and genomes, 15, 1, 3-11 2008/02 公開
Vandenbon A, Nakai K Vandenbon A, Nakai K Vandenbon A, Nakai K Using simple rules on presence and positioning of motifs for promoter structure modeling and tissue-specific expression prediction. Using simple rules on presence and positioning of motifs for promoter structure modeling and tissue-specific expression prediction. Using simple rules on presence and positioning of motifs for promoter structure modeling and tissue-specific expression prediction. Genome informatics. International Conference on Genome Informatics, 21, 188-199 Genome informatics. International Conference on Genome Informatics, 21, 188-199 Genome informatics. International Conference on Genome Informatics, 21, 188-199 2008 公開

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タイトル言語:
学術賞等
賞の名称(日本語) 賞の名称(英語) 授与組織名(日本語) 授与組織名(英語) 年月
Oxford Journals - Japanese Society for Bioinformatics Prize Oxford Journals - Japanese Society for Bioinformatics Prize 日本バイオインフォマティクス学会 Japanese Society for Bioinformatics 2019/09/10
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
科学研究費補助金 代表 免疫応答の制御に関与するプロモータの網羅的な構造特徴の抽出とモデル化 Comprehensive feature extraction and modeling of promoters controlling the immune response 2011/04/01〜2012/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
Basic Data Analysis-E2 Basic Data Analysis-E2 前期 全学共通科目 2018/04〜2019/03
ILAS Seminar-E2 ILAS Seminar-E2 前期 全学共通科目 2018/04〜2019/03
ILAS Seminar-E2 ILAS Seminar-E2 後期 全学共通科目 2018/04〜2019/03
Introductory Statistics-E2 Introductory Statistics-E2 後期 全学共通科目 2018/04〜2019/03
Basic Data Analysis-E2 Basic Data Analysis-E2 前期 全学共通科目 2019/04〜2020/03
ILAS Seminar-E2 ILAS Seminar-E2 前期 全学共通科目 2019/04〜2020/03
ILAS Seminar-E2 ILAS Seminar-E2 後期 全学共通科目 2019/04〜2020/03
Introductory Statistics-E2 Introductory Statistics-E2 後期 全学共通科目 2019/04〜2020/03