原 雄二

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氏名(漢字/フリガナ/アルファベット表記)
原 雄二/ハラ ユウジ/Hara, Yuji
所属部署・職名(部局/所属/講座等/職名)
工学研究科/合成・生物化学専攻生物化学講座/准教授
学部兼担
部局 所属 講座等 職名
工学部
学内兼務
部局 所属 講座等 職名
学際融合教育研究推進センター スーパーグローバルコース 化学系ユニット
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
修士(薬学) 京都大学
博士(理学) 総合研究大学院大学
ORCID ID
https://orcid.org/0000-0003-0021-1740
researchmap URL
https://researchmap.jp/yuji-hara
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Takuto Suito, Kohjiro Nagao, Masataka Hatano, Kenichi Kohashi, Aiko Tanabe, Hiromichi Ozaki, Jun Kawamoto, Tatsuo Kurihara, Tetsuo Mioka, Kazuma Tanaka, Yuji Hara, Masato Umeda Takuto Suito, Kohjiro Nagao, Masataka Hatano, Kenichi Kohashi, Aiko Tanabe, Hiromichi Ozaki, Jun Kawamoto, Tatsuo Kurihara, Tetsuo Mioka, Kazuma Tanaka, Yuji Hara, Masato Umeda Takuto Suito, Kohjiro Nagao, Masataka Hatano, Kenichi Kohashi, Aiko Tanabe, Hiromichi Ozaki, Jun Kawamoto, Tatsuo Kurihara, Tetsuo Mioka, Kazuma Tanaka, Yuji Hara, Masato Umeda Synthesis of omega-3 long-chain polyunsaturated fatty acid-rich triacylglycerols in an endemic goby, Gymnogobius isaza, from Lake Biwa, Japan Synthesis of omega-3 long-chain polyunsaturated fatty acid-rich triacylglycerols in an endemic goby, Gymnogobius isaza, from Lake Biwa, Japan Synthesis of omega-3 long-chain polyunsaturated fatty acid-rich triacylglycerols in an endemic goby, Gymnogobius isaza, from Lake Biwa, Japan JOURNAL OF BIOCHEMISTRY, 164, 2, 127-140 JOURNAL OF BIOCHEMISTRY, 164, 2, 127-140 JOURNAL OF BIOCHEMISTRY, 164, 2, 127-140 2018/08 英語 研究論文(学術雑誌) 公開
Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, Umeda M Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, Umeda M Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, Umeda M Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Nature communications, 9, 1, 2049 Nature communications, 9, 1, 2049 Nature communications, 9, 1, 2049 2018/05 公開
Sravani Banerjee, David Aponte-Diaz, Calvin Yeager, Suresh D. Sharma, Gang Ning, Hyung S. Oh, Qingxia Han, Masato Umeda, Yuji Hara, Robert Y. L. Wang, Craig E. Cameron Sravani Banerjee, David Aponte-Diaz, Calvin Yeager, Suresh D. Sharma, Gang Ning, Hyung S. Oh, Qingxia Han, Masato Umeda, Yuji Hara, Robert Y. L. Wang, Craig E. Cameron Sravani Banerjee, David Aponte-Diaz, Calvin Yeager, Suresh D. Sharma, Gang Ning, Hyung S. Oh, Qingxia Han, Masato Umeda, Yuji Hara, Robert Y. L. Wang, Craig E. Cameron Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein PLOS PATHOGENS, 14, 5, e1007086 PLOS PATHOGENS, 14, 5, e1007086 PLOS PATHOGENS, 14, 5, e1007086 2018/05 英語 研究論文(学術雑誌) 公開
Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga, Masato Umeda Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga, Masato Umeda Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga, Masato Umeda Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation NATURE COMMUNICATIONS, 9 NATURE COMMUNICATIONS, 9 NATURE COMMUNICATIONS, 9 2018/05 英語 研究論文(学術雑誌) 公開
Murakami A, Nagao K, Juni N, Hara Y, Umeda M Murakami A, Nagao K, Juni N, Hara Y, Umeda M Murakami A, Nagao K, Juni N, Hara Y, Umeda M An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in <i>Drosophila</i>. An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in <i>Drosophila</i>. An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in <i>Drosophila</i>. The Journal of biological chemistry, 292, 49, 19976-19986 The Journal of biological chemistry, 292, 49, 19976-19986 The Journal of biological chemistry, 292, 49, 19976-19986 2017/12 公開
Akira Murakami, Kohjiro Nagao, Naoto Juni, Yuji Hara, Masato Umeda Akira Murakami, Kohjiro Nagao, Naoto Juni, Yuji Hara, Masato Umeda Akira Murakami, Kohjiro Nagao, Naoto Juni, Yuji Hara, Masato Umeda An N-terminal di-proline motif is essential for fatty acid-dependent degradation of 9-desaturase in Drosophila An N-terminal di-proline motif is essential for fatty acid-dependent degradation of 9-desaturase in Drosophila An N-terminal di-proline motif is essential for fatty acid-dependent degradation of 9-desaturase in Drosophila JOURNAL OF BIOLOGICAL CHEMISTRY, 292, 49 JOURNAL OF BIOLOGICAL CHEMISTRY, 292, 49 JOURNAL OF BIOLOGICAL CHEMISTRY, 292, 49 2017/12 英語 研究論文(学術雑誌) 公開
F. Saito, H. Okuma, J. Mitsui, Y. Hara, Y. Hatanaka, M. Ikada, T. Shimizu, K. Matsumura, J. Shimizu, S. Tsuji, M. Sonoo F. Saito, H. Okuma, J. Mitsui, Y. Hara, Y. Hatanaka, M. Ikada, T. Shimizu, K. Matsumura, J. Shimizu, S. Tsuji, M. Sonoo F. Saito, H. Okuma, J. Mitsui, Y. Hara, Y. Hatanaka, M. Ikada, T. Shimizu, K. Matsumura, J. Shimizu, S. Tsuji, M. Sonoo Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1 Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1 Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1 NEUROMUSCULAR DISORDERS, 26 NEUROMUSCULAR DISORDERS, 26 NEUROMUSCULAR DISORDERS, 26 2016/10 英語 研究論文(学術雑誌) 公開
Okuma H, Saito F, Mitsui J, Hara Y, Hatanaka Y, Ikeda M, Shimizu T, Matsumura K, Shimizu J, Tsuji S, Sonoo M Okuma H, Saito F, Mitsui J, Hara Y, Hatanaka Y, Ikeda M, Shimizu T, Matsumura K, Shimizu J, Tsuji S, Sonoo M Okuma H, Saito F, Mitsui J, Hara Y, Hatanaka Y, Ikeda M, Shimizu T, Matsumura K, Shimizu J, Tsuji S, Sonoo M Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1. Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1. Tubular aggregate myopathy caused by a novel mutation in the cytoplasmic domain of STIM1. Neurology. Genetics, 2, 1, e50 Neurology. Genetics, 2, 1, e50 Neurology. Genetics, 2, 1, e50 2016/02 公開
土谷 正樹, 原 雄二, 梅田 眞郷 土谷 正樹, 原 雄二, 梅田 眞郷 生体膜におけるリン脂質ダイナミクスとその生物機能 生体膜におけるリン脂質ダイナミクスとその生物機能 膜, 41, 5 膜, 41, 5 , 41, 5 2016/01 日本語 研究論文(学術雑誌) 公開
土谷 正樹, 原 雄二, 梅田 眞郷 土谷 正樹, 原 雄二, 梅田 眞郷 特集 第38年会生体膜特別講演 生体膜におけるリン脂質ダイナミクスとその生物機能 特集 第38年会生体膜特別講演 生体膜におけるリン脂質ダイナミクスとその生物機能 膜 = Membrane, 41, 5 膜 = Membrane, 41, 5 , 41, 5 2016/01 日本語 研究論文(学術雑誌) 公開
Ogawa R, Nagao K, Taniuchi K, Tsuchiya M, Kato U, Hara Y, Inaba T, Kobayashi T, Sasaki Y, Akiyoshi K, Watanabe-Takahashi M, Nishikawa K, Umeda M Ogawa R, Nagao K, Taniuchi K, Tsuchiya M, Kato U, Hara Y, Inaba T, Kobayashi T, Sasaki Y, Akiyoshi K, Watanabe-Takahashi M, Nishikawa K, Umeda M Ogawa R, Nagao K, Taniuchi K, Tsuchiya M, Kato U, Hara Y, Inaba T, Kobayashi T, Sasaki Y, Akiyoshi K, Watanabe-Takahashi M, Nishikawa K, Umeda M Development of a Novel Tetravalent Synthetic Peptide That Binds to Phosphatidic Acid. Development of a Novel Tetravalent Synthetic Peptide That Binds to Phosphatidic Acid. Development of a Novel Tetravalent Synthetic Peptide That Binds to Phosphatidic Acid. PloS one, 10, 7, e0131668 PloS one, 10, 7, e0131668 PloS one, 10, 7, e0131668 2015 公開
Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, Beltrán Valero de Bernabé D, Yu L, Wright KM, Campbell KP Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, Beltrán Valero de Bernabé D, Yu L, Wright KM, Campbell KP Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, Beltrán Valero de Bernabé D, Yu L, Wright KM, Campbell KP The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. eLife, 3 eLife, 3 eLife, 3 2014/10 公開
Inamori K, Willer T, Hara Y, Venzke D, Anderson ME, Clarke NF, Guicheney P, Bönnemann CG, Moore SA, Campbell KP Inamori K, Willer T, Hara Y, Venzke D, Anderson ME, Clarke NF, Guicheney P, Bönnemann CG, Moore SA, Campbell KP Inamori K, Willer T, Hara Y, Venzke D, Anderson ME, Clarke NF, Guicheney P, Bönnemann CG, Moore SA, Campbell KP Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues. Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues. Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues. The Journal of biological chemistry, 289, 41, 28138-28148 The Journal of biological chemistry, 289, 41, 28138-28148 The Journal of biological chemistry, 289, 41, 28138-28148 2014/10 公開
Tobias Willer, Kei-ichiro Inamori, David Venzke, Corinne Harvey, Greg Morgensen, Yuji Hara, Daniel Beltrán Valero de Bernabé, Liping Yu, Kevin M Wright, Kevin P Campbell Tobias Willer, Kei-ichiro Inamori, David Venzke, Corinne Harvey, Greg Morgensen, Yuji Hara, Daniel Beltrán Valero de Bernabé, Liping Yu, Kevin M Wright, Kevin P Campbell Tobias Willer, Kei-ichiro Inamori, David Venzke, Corinne Harvey, Greg Morgensen, Yuji Hara, Daniel Beltrán Valero de Bernabé, Liping Yu, Kevin M Wright, Kevin P Campbell The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation eLife, 3 eLife, 3 eLife, 3 2014/10 英語 研究論文(学術雑誌) 公開
Y. Endo, S. Noguchi, Y. Hara, Y. K. Hayashi, K. Motomura, S. Miyatake, N. Murakami, S. Tanaka, S. Yamashita, R. Kizu, M. Bamba, Y.-i. Goto, N. Matsumoto, I. Nonaka, I. Nishino Y. Endo, S. Noguchi, Y. Hara, Y. K. Hayashi, K. Motomura, S. Miyatake, N. Murakami, S. Tanaka, S. Yamashita, R. Kizu, M. Bamba, Y.-i. Goto, N. Matsumoto, I. Nonaka, I. Nishino Y. Endo, S. Noguchi, Y. Hara, Y. K. Hayashi, K. Motomura, S. Miyatake, N. Murakami, S. Tanaka, S. Yamashita, R. Kizu, M. Bamba, Y.-i. Goto, N. Matsumoto, I. Nonaka, I. Nishino Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channels Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channels Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channels Human Molecular Genetics, 24, 3, 637-648 Human Molecular Genetics, 24, 3, 637-648 Human Molecular Genetics, 24, 3, 637-648 2014/09 英語 研究論文(学術雑誌) 公開
Kei-ichiro Inamori, Tobias Willer, Yuji Hara, David Venzke, Mary E. Anderson, Nigel F. Clarke, Pascale Guicheney, Carsten G. Bönnemann, Steven A. Moore, Kevin P. Campbell Kei-ichiro Inamori, Tobias Willer, Yuji Hara, David Venzke, Mary E. Anderson, Nigel F. Clarke, Pascale Guicheney, Carsten G. Bönnemann, Steven A. Moore, Kevin P. Campbell Kei-ichiro Inamori, Tobias Willer, Yuji Hara, David Venzke, Mary E. Anderson, Nigel F. Clarke, Pascale Guicheney, Carsten G. Bönnemann, Steven A. Moore, Kevin P. Campbell Endogenous Glucuronyltransferase Activity of LARGE or LARGE2 Required for Functional Modification of α-Dystroglycan in Cells and Tissues Endogenous Glucuronyltransferase Activity of LARGE or LARGE2 Required for Functional Modification of α-Dystroglycan in Cells and Tissues Endogenous Glucuronyltransferase Activity of LARGE or LARGE2 Required for Functional Modification of α-Dystroglycan in Cells and Tissues JOURNAL OF BIOLOGICAL CHEMISTRY, 289 JOURNAL OF BIOLOGICAL CHEMISTRY, 289 JOURNAL OF BIOLOGICAL CHEMISTRY, 289 2014/08 英語 研究論文(学術雑誌) 公開
K.-i. Inamori, Y. Hara, T. Willer, M. E. Anderson, Z. Zhu, T. Yoshida-Moriguchi, K. P. Campbell K.-i. Inamori, Y. Hara, T. Willer, M. E. Anderson, Z. Zhu, T. Yoshida-Moriguchi, K. P. Campbell K.-i. Inamori, Y. Hara, T. Willer, M. E. Anderson, Z. Zhu, T. Yoshida-Moriguchi, K. P. Campbell Xylosyl- and glucuronyltransferase functions of LARGE in  -dystroglycan modification are conserved in LARGE2 Xylosyl- and glucuronyltransferase functions of LARGE in  -dystroglycan modification are conserved in LARGE2 Xylosyl- and glucuronyltransferase functions of LARGE in  -dystroglycan modification are conserved in LARGE2 Glycobiology, 23, 3, 295-302 Glycobiology, 23, 3, 295-302 Glycobiology, 23, 3, 295-302 2012/11 英語 研究論文(学術雑誌) 公開
Katano M, Numata T, Aguan K, Hara Y, Kiyonaka S, Yamamoto S, Miki T, Sawamura S, Suzuki T, Yamakawa K, Mori Y Katano M, Numata T, Aguan K, Hara Y, Kiyonaka S, Yamamoto S, Miki T, Sawamura S, Suzuki T, Yamakawa K, Mori Y Katano M, Numata T, Aguan K, Hara Y, Kiyonaka S, Yamamoto S, Miki T, Sawamura S, Suzuki T, Yamakawa K, Mori Y The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death. The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death. The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death. Cell calcium, 51, 2, 179-185 Cell calcium, 51, 2, 179-185 Cell calcium, 51, 2, 179-185 2012/02 公開
Inamori K, Yoshida-Moriguchi T, Hara Y, Anderson ME, Yu L, Campbell KP Inamori K, Yoshida-Moriguchi T, Hara Y, Anderson ME, Yu L, Campbell KP Inamori K, Yoshida-Moriguchi T, Hara Y, Anderson ME, Yu L, Campbell KP Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Science (New York, N.Y.), 335, 6064, 93-96 Science (New York, N.Y.), 335, 6064, 93-96 Science (New York, N.Y.), 335, 6064, 93-96 2012/01 公開
Hara Y, Furutani T, Murakami A, Palijon AM, Yokohari M Hara Y, Furutani T, Murakami A, Palijon AM, Yokohari M Hara Y, Furutani T, Murakami A, Palijon AM, Yokohari M Current organic waste recycling and the potential for local recycling through urban agriculture in Metro Manila. Current organic waste recycling and the potential for local recycling through urban agriculture in Metro Manila. Current organic waste recycling and the potential for local recycling through urban agriculture in Metro Manila. Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 29, 11, 1213-1221 Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 29, 11, 1213-1221 Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 29, 11, 1213-1221 2011/11 公開
Hara Y, Kanagawa M, Kunz S, Yoshida-Moriguchi T, Satz JS, Kobayashi YM, Zhu Z, Burden SJ, Oldstone MB, Campbell KP Hara Y, Kanagawa M, Kunz S, Yoshida-Moriguchi T, Satz JS, Kobayashi YM, Zhu Z, Burden SJ, Oldstone MB, Campbell KP Hara Y, Kanagawa M, Kunz S, Yoshida-Moriguchi T, Satz JS, Kobayashi YM, Zhu Z, Burden SJ, Oldstone MB, Campbell KP Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection. Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection. Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection. Proceedings of the National Academy of Sciences of the United States of America, 108, 42, 17426-17431 Proceedings of the National Academy of Sciences of the United States of America, 108, 42, 17426-17431 Proceedings of the National Academy of Sciences of the United States of America, 108, 42, 17426-17431 2011/10 公開
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, Beltrán-Valero de Bernabé D, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ, Kunz S, Oldstone MB, Accardi A, Talim B, Muntoni F, Topaloğlu H, Dinçer P, Campbell KP Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, Beltrán-Valero de Bernabé D, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ, Kunz S, Oldstone MB, Accardi A, Talim B, Muntoni F, Topaloğlu H, Dinçer P, Campbell KP Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, Beltrán-Valero de Bernabé D, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ, Kunz S, Oldstone MB, Accardi A, Talim B, Muntoni F, Topaloğlu H, Dinçer P, Campbell KP A dystroglycan mutation associated with limb-girdle muscular dystrophy. A dystroglycan mutation associated with limb-girdle muscular dystrophy. A dystroglycan mutation associated with limb-girdle muscular dystrophy. The New England journal of medicine, 364, 10, 939-946 The New England journal of medicine, 364, 10, 939-946 The New England journal of medicine, 364, 10, 939-946 2011/03 公開
Hiramatsu A, Hara Y, Sekiyama M, Honda R, Chiemchaisri C Hiramatsu A, Hara Y, Sekiyama M, Honda R, Chiemchaisri C Hiramatsu A, Hara Y, Sekiyama M, Honda R, Chiemchaisri C Municipal solid waste flow and waste generation characteristics in an urban--rural fringe area in Thailand. Municipal solid waste flow and waste generation characteristics in an urban--rural fringe area in Thailand. Municipal solid waste flow and waste generation characteristics in an urban--rural fringe area in Thailand. Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 27, 10, 951-960 Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 27, 10, 951-960 Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA, 27, 10, 951-960 2009/12 公開
Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nature medicine, 14, 7, 738-747 Nature medicine, 14, 7, 738-747 Nature medicine, 14, 7, 738-747 2008/07 公開
Yamamoto S, Wajima T, Hara Y, Nishida M, Mori Y Yamamoto S, Wajima T, Hara Y, Nishida M, Mori Y Yamamoto S, Wajima T, Hara Y, Nishida M, Mori Y Transient receptor potential channels in Alzheimer's disease. Transient receptor potential channels in Alzheimer's disease. Transient receptor potential channels in Alzheimer's disease. Biochimica et biophysica acta, 1772, 8, 958-967 Biochimica et biophysica acta, 1772, 8, 958-967 Biochimica et biophysica acta, 1772, 8, 958-967 2007/08 公開
Kiyonaka S, Wakamori M, Miki T, Uriu Y, Nonaka M, Bito H, Beedle AM, Mori E, Hara Y, De Waard M, Kanagawa M, Itakura M, Takahashi M, Campbell KP, Mori Y Kiyonaka S, Wakamori M, Miki T, Uriu Y, Nonaka M, Bito H, Beedle AM, Mori E, Hara Y, De Waard M, Kanagawa M, Itakura M, Takahashi M, Campbell KP, Mori Y Kiyonaka S, Wakamori M, Miki T, Uriu Y, Nonaka M, Bito H, Beedle AM, Mori E, Hara Y, De Waard M, Kanagawa M, Itakura M, Takahashi M, Campbell KP, Mori Y RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nature neuroscience, 10, 6, 691-701 Nature neuroscience, 10, 6, 691-701 Nature neuroscience, 10, 6, 691-701 2007/06 公開
Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nature chemical biology, 2, 11, 596-607 Nature chemical biology, 2, 11, 596-607 Nature chemical biology, 2, 11, 596-607 2006/11 公開
Nishida M, Hara Y, Yoshida T, Inoue R, Mori Y Nishida M, Hara Y, Yoshida T, Inoue R, Mori Y Nishida M, Hara Y, Yoshida T, Inoue R, Mori Y TRP channels: molecular diversity and physiological function. TRP channels: molecular diversity and physiological function. TRP channels: molecular diversity and physiological function. Microcirculation (New York, N.Y. : 1994), 13, 7, 535-550 Microcirculation (New York, N.Y. : 1994), 13, 7, 535-550 Microcirculation (New York, N.Y. : 1994), 13, 7, 535-550 2006/10 公開
Ishii M, Shimizu S, Hara Y, Hagiwara T, Miyazaki A, Mori Y, Kiuchi Y Ishii M, Shimizu S, Hara Y, Hagiwara T, Miyazaki A, Mori Y, Kiuchi Y Ishii M, Shimizu S, Hara Y, Hagiwara T, Miyazaki A, Mori Y, Kiuchi Y Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F. Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F. Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F. Cell calcium, 39, 6, 487-494 Cell calcium, 39, 6, 487-494 Cell calcium, 39, 6, 487-494 2006/06 公開
Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. Journal of pharmacological sciences, 101, 1, 66-76 Journal of pharmacological sciences, 101, 1, 66-76 Journal of pharmacological sciences, 101, 1, 66-76 2006/05 公開
Togashi K, Hara Y, Tominaga T, Higashi T, Konishi Y, Mori Y, Tominaga M Togashi K, Hara Y, Tominaga T, Higashi T, Konishi Y, Mori Y, Tominaga M Togashi K, Hara Y, Tominaga T, Higashi T, Konishi Y, Mori Y, Tominaga M TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. The EMBO journal, 25, 9, 1804-1815 The EMBO journal, 25, 9, 1804-1815 The EMBO journal, 25, 9, 1804-1815 2006/05 公開
Kang MG, Chen CC, Wakamori M, Hara Y, Mori Y, Campbell KP Kang MG, Chen CC, Wakamori M, Hara Y, Mori Y, Campbell KP Kang MG, Chen CC, Wakamori M, Hara Y, Mori Y, Campbell KP A functional AMPA receptor-calcium channel complex in the postsynaptic membrane. A functional AMPA receptor-calcium channel complex in the postsynaptic membrane. A functional AMPA receptor-calcium channel complex in the postsynaptic membrane. Proceedings of the National Academy of Sciences of the United States of America, 103, 14, 5561-5566 Proceedings of the National Academy of Sciences of the United States of America, 103, 14, 5561-5566 Proceedings of the National Academy of Sciences of the United States of America, 103, 14, 5561-5566 2006/04 公開
Lievremont JP, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Moss SE, Bird GS, Mori Y, Putney JW Jr Lievremont JP, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Moss SE, Bird GS, Mori Y, Putney JW Jr Lievremont JP, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Moss SE, Bird GS, Mori Y, Putney JW Jr The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. The Journal of biological chemistry, 280, 42, 35346-35351 The Journal of biological chemistry, 280, 42, 35346-35351 The Journal of biological chemistry, 280, 42, 35346-35351 2005/10 公開
Mio K, Ogura T, Hara Y, Mori Y, Sato C Mio K, Ogura T, Hara Y, Mori Y, Sato C Mio K, Ogura T, Hara Y, Mori Y, Sato C The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end. The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end. The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end. Biochemical and biophysical research communications, 333, 3, 768-777 Biochemical and biophysical research communications, 333, 3, 768-777 Biochemical and biophysical research communications, 333, 3, 768-777 2005/08 公開
Okamura Y, Nishino A, Murata Y, Nakajo K, Iwasaki H, Ohtsuka Y, Tanaka-Kunishima M, Takahashi N, Hara Y, Yoshida T, Nishida M, Okado H, Watari H, Meinertzhagen IA, Satoh N, Takahashi K, Satou Y, Okada Y, Mori Y Okamura Y, Nishino A, Murata Y, Nakajo K, Iwasaki H, Ohtsuka Y, Tanaka-Kunishima M, Takahashi N, Hara Y, Yoshida T, Nishida M, Okado H, Watari H, Meinertzhagen IA, Satoh N, Takahashi K, Satou Y, Okada Y, Mori Y Okamura Y, Nishino A, Murata Y, Nakajo K, Iwasaki H, Ohtsuka Y, Tanaka-Kunishima M, Takahashi N, Hara Y, Yoshida T, Nishida M, Okado H, Watari H, Meinertzhagen IA, Satoh N, Takahashi K, Satou Y, Okada Y, Mori Y Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Physiological genomics, 22, 3, 269-282 Physiological genomics, 22, 3, 269-282 Physiological genomics, 22, 3, 269-282 2005/08 公開
Suzuki T, Delgado-Escueta AV, Aguan K, Alonso ME, Shi J, Hara Y, Nishida M, Numata T, Medina MT, Takeuchi T, Morita R, Bai D, Ganesh S, Sugimoto Y, Inazawa J, Bailey JN, Ochoa A, Jara-Prado A, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Inoue Y, Osawa M, Kaneko S, Oguni H, Mori Y, Yamakawa K Suzuki T, Delgado-Escueta AV, Aguan K, Alonso ME, Shi J, Hara Y, Nishida M, Numata T, Medina MT, Takeuchi T, Morita R, Bai D, Ganesh S, Sugimoto Y, Inazawa J, Bailey JN, Ochoa A, Jara-Prado A, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Inoue Y, Osawa M, Kaneko S, Oguni H, Mori Y, Yamakawa K Suzuki T, Delgado-Escueta AV, Aguan K, Alonso ME, Shi J, Hara Y, Nishida M, Numata T, Medina MT, Takeuchi T, Morita R, Bai D, Ganesh S, Sugimoto Y, Inazawa J, Bailey JN, Ochoa A, Jara-Prado A, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Inoue Y, Osawa M, Kaneko S, Oguni H, Mori Y, Yamakawa K Mutations in EFHC1 cause juvenile myoclonic epilepsy. Mutations in EFHC1 cause juvenile myoclonic epilepsy. Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nature genetics, 36, 8, 842-849 Nature genetics, 36, 8, 842-849 Nature genetics, 36, 8, 842-849 2004/08 公開
Ogimoto A, Hamada M, Ohtsuka T, Hara Y, Shigematsu Y, Yokoyama A, Imagawa H, Kawachi K, Kito K, Higaki J Ogimoto A, Hamada M, Ohtsuka T, Hara Y, Shigematsu Y, Yokoyama A, Imagawa H, Kawachi K, Kito K, Higaki J Ogimoto A, Hamada M, Ohtsuka T, Hara Y, Shigematsu Y, Yokoyama A, Imagawa H, Kawachi K, Kito K, Higaki J Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis. Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis. Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis. Internal medicine (Tokyo, Japan), 42, 9, 827-830 Internal medicine (Tokyo, Japan), 42, 9, 827-830 Internal medicine (Tokyo, Japan), 42, 9, 827-830 2003/09 公開
Nishida M, Sugimoto K, Hara Y, Mori E, Morii T, Kurosaki T, Mori Y Nishida M, Sugimoto K, Hara Y, Mori E, Morii T, Kurosaki T, Mori Y Nishida M, Sugimoto K, Hara Y, Mori E, Morii T, Kurosaki T, Mori Y Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. The EMBO journal, 22, 18, 4677-4688 The EMBO journal, 22, 18, 4677-4688 The EMBO journal, 22, 18, 4677-4688 2003/09 公開
Nishida M, Hara Y, Inoue R, Mori Y Nishida M, Hara Y, Inoue R, Mori Y Nishida M, Hara Y, Inoue R, Mori Y TRP channels: formation of signal complex and regulation of cellular functions. TRP channels: formation of signal complex and regulation of cellular functions. TRP channels: formation of signal complex and regulation of cellular functions. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 121, 4, 223-232 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 121, 4, 223-232 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 121, 4, 223-232 2003/04 公開
Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, Kurosaki T Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, Kurosaki T Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, Kurosaki T Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. The Journal of experimental medicine, 195, 6, 673-681 The Journal of experimental medicine, 195, 6, 673-681 The Journal of experimental medicine, 195, 6, 673-681 2002/03 公開
Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T, Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T, Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T, Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Molecular cell, 9, 1, 163-173 Molecular cell, 9, 1, 163-173 Molecular cell, 9, 1, 163-173 2002/01 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 出版社 出版社(日本語) 出版社(英語) 出版年月 記述言語 担当区分 公開
Yuji Hara Yuji Hara Yuji Hara Glycoscience: Biology and Medicine Glycoscience: Biology and Medicine Dystroglycan: Extracellular Matrix Receptor that Links to Cytoskeleton Springer International Publishing Springer International Publishing 2014/10 分担執筆 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
挑戦的萌芽研究 代表 自閉症発症機構解明を志向した細胞接着因子結合タンパク質群の同定 2013〜2014
挑戦的萌芽研究 代表 自閉症発症機構解明を志向した細胞接着因子結合タンパク質群の同定 (平成26年度分) 2014/04/01〜2015/03/31
挑戦的萌芽研究 代表 筋ジストロフィー克服を志向したペプチド医薬創生 (平成27年度分) 2015/04/01〜2016/03/31
挑戦的萌芽研究 代表 筋ジストロフィー克服を志向したペプチド医薬創生 (平成28年度分) 2016/04/01〜2017/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
生物化学工学 Biochemical Engineering 後期 工学部 2014/04〜2015/03
生化学II Basic Biochemistry II 後期 工学部 2014/04〜2015/03
生命化学基礎(工業基礎化学) Chemical Basis of Life(Fundamental Chemistry) 後期 工学部 2014/04〜2015/03
先端生物化学 Advanced Biological Chemistry 前期 工学研究科 2014/04〜2015/03
先端生物化学 Advanced Biological Chemistry 前期 工学研究科 2015/04〜2016/03
先端生物化学続論 Advanced Biological Chemistry 2 Continued 前期 工学研究科 2015/04〜2016/03
生体認識化学 Biorecognics 前期 工学研究科 2015/04〜2016/03
生化学II Basic Biochemistry II 後期 工学部 2015/04〜2016/03
生化学I(工業基礎化学) Basic Biochemistry I (Fundamental Chemistry) 前期 工学部 2015/04〜2016/03
生命化学基礎(工業基礎化学) Chemical Basis of Life(Fundamental Chemistry) 後期 工学部 2015/04〜2016/03
生物化学工学 Biochemical Engineering 後期 工学部 2015/04〜2016/03
先端生物化学 Advanced Biological Chemistry 前期 工学研究科 2016/04〜2017/03
先端生物化学続論 Advanced Biological Chemistry 2 Continued 前期 工学研究科 2016/04〜2017/03
生化学II Basic Biochemistry II 後期 工学部 2016/04〜2017/03
生化学I(工業基礎化学) Basic Biochemistry I (Fundamental Chemistry) 前期 工学部 2016/04〜2017/03
生命化学基礎(工業基礎化学) Chemical Basis of Life(Fundamental Chemistry) 後期 工学部 2016/04〜2017/03
生物化学工学 Biochemical Engineering 後期 工学部 2016/04〜2017/03
先端生物化学 Advanced Biological Chemistry 前期 工学研究科 2017/04〜2018/03
先端生物化学続論 Advanced Biological Chemistry 2 Continued 前期 工学研究科 2017/04〜2018/03
生体認識化学 Biorecognics 前期 工学研究科 2017/04〜2018/03
生化学II Basic Biochemistry II 後期 工学部 2017/04〜2018/03
生化学I(工業基礎化学) Basic Biochemistry I (Fundamental Chemistry) 前期 工学部 2017/04〜2018/03
生命化学基礎(工業基礎化学) Chemical Basis of Life(Fundamental Chemistry) 後期 工学部 2017/04〜2018/03
生物化学工学 Biochemical Engineering 後期 工学部 2017/04〜2018/03
先端生物化学 Advanced Biological Chemistry 前期 工学研究科 2018/04〜2019/03
先端生物化学続論 Advanced Biological Chemistry 2 Continued 前期 工学研究科 2018/04〜2019/03
生化学II Basic Biochemistry II 後期 工学部 2018/04〜2019/03
生化学I(工業基礎化学) Basic Biochemistry I (Fundamental Chemistry) 前期 工学部 2018/04〜2019/03
生命化学基礎(工業基礎化学) Chemical Basis of Life(Fundamental Chemistry) 後期 工学部 2018/04〜2019/03
生物化学工学 Biochemical Engineering 後期 工学部 2018/04〜2019/03

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部局運営(役職等)
役職名 期間
工学研究科・工学部図書委員会 委員 2015/04/01〜2017/03/31