藤田 恭之

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氏名(漢字/フリガナ/アルファベット表記)
藤田 恭之/フジタ ヤスユキ/Fujita, Yasuyuki
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学専攻分子生体統御学講座分子腫瘍学/教授
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学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
researchmap URL
https://researchmap.jp/1234munc
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Nanami Sato, Yuta Yako, Takeshi Maruyama, Susumu Ishikawa, Keisuke Kuromiya, Suzumi M. Tokuoka, Yoshihiro Kita, Yasuyuki Fujita Nanami Sato, Yuta Yako, Takeshi Maruyama, Susumu Ishikawa, Keisuke Kuromiya, Suzumi M. Tokuoka, Yoshihiro Kita, Yasuyuki Fujita Nanami Sato, Yuta Yako, Takeshi Maruyama, Susumu Ishikawa, Keisuke Kuromiya, Suzumi M. Tokuoka, Yoshihiro Kita, Yasuyuki Fujita The COX-2/PGE2 pathway suppresses apical elimination of RasV12-transformed cells from epithelia The COX-2/PGE2 pathway suppresses apical elimination of RasV12-transformed cells from epithelia The COX-2/PGE2 pathway suppresses apical elimination of RasV12-transformed cells from epithelia Communications Biology, 3, 1 Communications Biology, 3, 1 Communications Biology, 3, 1 2020/03/18 研究論文(学術雑誌) 公開
Erika Ishihara, Yuya Nagaoka, Toshiaki Okuno, Satoshi Kofuji, Mari Ishigami‐Yuasa, Hiroyuki Kagechika, Kenya Kamimura, Shuji Terai, Takehiko Yokomizo, Yukihiko Sugimoto, Yasuyuki Fujita, Akira Suzuki, Hiroshi Nishina Erika Ishihara, Yuya Nagaoka, Toshiaki Okuno, Satoshi Kofuji, Mari Ishigami‐Yuasa, Hiroyuki Kagechika, Kenya Kamimura, Shuji Terai, Takehiko Yokomizo, Yukihiko Sugimoto, Yasuyuki Fujita, Akira Suzuki, Hiroshi Nishina Erika Ishihara, Yuya Nagaoka, Toshiaki Okuno, Satoshi Kofuji, Mari Ishigami‐Yuasa, Hiroyuki Kagechika, Kenya Kamimura, Shuji Terai, Takehiko Yokomizo, Yukihiko Sugimoto, Yasuyuki Fujita, Akira Suzuki, Hiroshi Nishina Prostaglandin E 2 and its receptor EP2 trigger signaling that contributes to YAP‐mediated cell competition Prostaglandin E 2 and its receptor EP2 trigger signaling that contributes to YAP‐mediated cell competition Prostaglandin E 2 and its receptor EP2 trigger signaling that contributes to YAP‐mediated cell competition Genes to Cells, 25, 3, 197-214 Genes to Cells, 25, 3, 197-214 Genes to Cells, 25, 3, 197-214 2020/03 研究論文(学術雑誌) 公開
Yasuto Takeuchi, Rika Narumi, Ryutaro Akiyama, Elisa Vitiello, Takanobu Shirai, Nobuyuki Tanimura, Keisuke Kuromiya, Susumu Ishikawa, Mihoko Kajita, Masazumi Tada, Yukinari Haraoka, Yuki Akieda, Tohru Ishitani, Yoichiro Fujioka, Yusuke Ohba, Sohei Yamada, Yoichiroh Hosokawa, Yusuke Toyama, Takaaki Matsui, Yasuyuki Fujita Yasuto Takeuchi, Rika Narumi, Ryutaro Akiyama, Elisa Vitiello, Takanobu Shirai, Nobuyuki Tanimura, Keisuke Kuromiya, Susumu Ishikawa, Mihoko Kajita, Masazumi Tada, Yukinari Haraoka, Yuki Akieda, Tohru Ishitani, Yoichiro Fujioka, Yusuke Ohba, Sohei Yamada, Yoichiroh Hosokawa, Yusuke Toyama, Takaaki Matsui, Yasuyuki Fujita Yasuto Takeuchi, Rika Narumi, Ryutaro Akiyama, Elisa Vitiello, Takanobu Shirai, Nobuyuki Tanimura, Keisuke Kuromiya, Susumu Ishikawa, Mihoko Kajita, Masazumi Tada, Yukinari Haraoka, Yuki Akieda, Tohru Ishitani, Yoichiro Fujioka, Yusuke Ohba, Sohei Yamada, Yoichiroh Hosokawa, Yusuke Toyama, Takaaki Matsui, Yasuyuki Fujita Calcium Wave Promotes Cell Extrusion. Calcium Wave Promotes Cell Extrusion. Calcium Wave Promotes Cell Extrusion. Current biology : CB, 30, 4, 670-681 Current biology : CB, 30, 4, 670-681 Current biology : CB, 30, 4, 670-681 2020/02/24 英語 公開
Fujita Y Fujita Y Fujita Y Flower power as human cancer cells compete with normal cells. Flower power as human cancer cells compete with normal cells. Flower power as human cancer cells compete with normal cells. Nature, 572, 7768, 181-182 Nature, 572, 7768, 181-182 Nature, 572, 7768, 181-182 2019/08 公開
Tanimura N, Fujita Y Tanimura N, Fujita Y Tanimura N, Fujita Y Epithelial defense against cancer (EDAC). Epithelial defense against cancer (EDAC). Epithelial defense against cancer (EDAC). Seminars in cancer biology Seminars in cancer biology Seminars in cancer biology 2019/07 公開
Nargess Khalilgharibi, Jonathan Fouchard, Nina Asadipour, Ricardo Barrientos, Maria Duda, Alessandra Bonfanti, Amina Yonis, Andrew Harris, Payman Mosaffa, Yasuyuki Fujita, Alexandre Kabla, Yanlan Mao, Buzz Baum, José J Muñoz, Mark Miodownik, Guillaume Charras Nargess Khalilgharibi, Jonathan Fouchard, Nina Asadipour, Ricardo Barrientos, Maria Duda, Alessandra Bonfanti, Amina Yonis, Andrew Harris, Payman Mosaffa, Yasuyuki Fujita, Alexandre Kabla, Yanlan Mao, Buzz Baum, José J Muñoz, Mark Miodownik, Guillaume Charras Nargess Khalilgharibi, Jonathan Fouchard, Nina Asadipour, Ricardo Barrientos, Maria Duda, Alessandra Bonfanti, Amina Yonis, Andrew Harris, Payman Mosaffa, Yasuyuki Fujita, Alexandre Kabla, Yanlan Mao, Buzz Baum, José J Muñoz, Mark Miodownik, Guillaume Charras Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex Nature Physics, 15, 8, 839-847 Nature Physics, 15, 8, 839-847 Nature Physics, 15, 8, 839-847 2019/05/13 研究論文(学術雑誌) 公開
Miki Nishio, Yousuke Miyachi, Junji Otani, Shoji Tane, Hirofumi Omori, Fumihito Ueda, Hideru Togashi, Takehiko Sasaki, Tak Wah Mak, Kazuwa Nakao, Yasuyuki Fujita, Hiroshi Nishina, Tomohiko Maehama, Akira Suzuki Miki Nishio, Yousuke Miyachi, Junji Otani, Shoji Tane, Hirofumi Omori, Fumihito Ueda, Hideru Togashi, Takehiko Sasaki, Tak Wah Mak, Kazuwa Nakao, Yasuyuki Fujita, Hiroshi Nishina, Tomohiko Maehama, Akira Suzuki Miki Nishio, Yousuke Miyachi, Junji Otani, Shoji Tane, Hirofumi Omori, Fumihito Ueda, Hideru Togashi, Takehiko Sasaki, Tak Wah Mak, Kazuwa Nakao, Yasuyuki Fujita, Hiroshi Nishina, Tomohiko Maehama, Akira Suzuki Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency. Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency. Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, 4, 5548-5560 FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, 4, 5548-5560 FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, 4, 5548-5560 2019/04 英語 研究論文(学術雑誌) 公開
Yuki Fujii, Yuki Ochi, Masahiro Tuchiya, Mihoko Kajita, Yasuyuki Fujita, Yukitaka Ishimoto, Takaharu Okajima Yuki Fujii, Yuki Ochi, Masahiro Tuchiya, Mihoko Kajita, Yasuyuki Fujita, Yukitaka Ishimoto, Takaharu Okajima Yuki Fujii, Yuki Ochi, Masahiro Tuchiya, Mihoko Kajita, Yasuyuki Fujita, Yukitaka Ishimoto, Takaharu Okajima Spontaneous Spatial Correlation of Elastic Modulus in Jammed Epithelial Monolayers Observed by AFM. Spontaneous Spatial Correlation of Elastic Modulus in Jammed Epithelial Monolayers Observed by AFM. Spontaneous Spatial Correlation of Elastic Modulus in Jammed Epithelial Monolayers Observed by AFM. Biophysical journal, 116, 6, 1152-1158 Biophysical journal, 116, 6, 1152-1158 Biophysical journal, 116, 6, 1152-1158 2019/03/19 英語 研究論文(学術雑誌) 公開
Koso H, Tsuhako A, Matsubara D, Fujita Y, Watanabe S Koso H, Tsuhako A, Matsubara D, Fujita Y, Watanabe S Koso H, Tsuhako A, Matsubara D, Fujita Y, Watanabe S Ras activation in retinal progenitor cells induces tumor formation in the eye. Ras activation in retinal progenitor cells induces tumor formation in the eye. Ras activation in retinal progenitor cells induces tumor formation in the eye. Experimental eye research, 180, 39-42 Experimental eye research, 180, 39-42 Experimental eye research, 180, 39-42 2019/03 公開
Søgaard PP, Ito N, Sato N, Fujita Y, Matter K, Itoh Y Søgaard PP, Ito N, Sato N, Fujita Y, Matter K, Itoh Y Søgaard PP, Ito N, Sato N, Fujita Y, Matter K, Itoh Y Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility. Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility. Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility. Life science alliance, 2, 1 Life science alliance, 2, 1 Life science alliance, 2, 1 2019/02 公開
Takagi M, Ikegawa M, Shimada T, Ishikawa S, Kajita M, Maruyama T, Kamasaki T, Fujita Y Takagi M, Ikegawa M, Shimada T, Ishikawa S, Kajita M, Maruyama T, Kamasaki T, Fujita Y Takagi M, Ikegawa M, Shimada T, Ishikawa S, Kajita M, Maruyama T, Kamasaki T, Fujita Y Accumulation of the myosin-II-spectrin complex plays a positive role in apical extrusion of Src-transformed epithelial cells. Accumulation of the myosin-II-spectrin complex plays a positive role in apical extrusion of Src-transformed epithelial cells. Accumulation of the myosin-II-spectrin complex plays a positive role in apical extrusion of Src-transformed epithelial cells. Genes to cells : devoted to molecular & cellular mechanisms, 23, 11, 974-981 Genes to cells : devoted to molecular & cellular mechanisms, 23, 11, 974-981 Genes to cells : devoted to molecular & cellular mechanisms, 23, 11, 974-981 2018/11 公開
Anton KA, Kajita M, Narumi R, Fujita Y, Tada M Anton KA, Kajita M, Narumi R, Fujita Y, Tada M Anton KA, Kajita M, Narumi R, Fujita Y, Tada M Src-transformed cells hijack mitosis to extrude from the epithelium. Src-transformed cells hijack mitosis to extrude from the epithelium. Src-transformed cells hijack mitosis to extrude from the epithelium. Nature communications, 9, 1, 4695 Nature communications, 9, 1, 4695 Nature communications, 9, 1, 4695 2018/11 公開
Yako Y, Hayashi T, Takeuchi Y, Ishibashi K, Kasai N, Sato N, Kuromiya K, Ishikawa S, Fujita Y Yako Y, Hayashi T, Takeuchi Y, Ishibashi K, Kasai N, Sato N, Kuromiya K, Ishikawa S, Fujita Y Yako Y, Hayashi T, Takeuchi Y, Ishibashi K, Kasai N, Sato N, Kuromiya K, Ishikawa S, Fujita Y ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells. ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells. ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells. Scientific reports, 8, 1, 9639 Scientific reports, 8, 1, 9639 Scientific reports, 8, 1, 9639 2018/06 公開
Watanabe H, Ishibashi K, Mano H, Kitamoto S, Sato N, Hoshiba K, Kato M, Matsuzawa F, Takeuchi Y, Shirai T, Ishikawa S, Morioka Y, Imagawa T, Sakaguchi K, Yonezawa S, Kon S, Fujita Y Watanabe H, Ishibashi K, Mano H, Kitamoto S, Sato N, Hoshiba K, Kato M, Matsuzawa F, Takeuchi Y, Shirai T, Ishikawa S, Morioka Y, Imagawa T, Sakaguchi K, Yonezawa S, Kon S, Fujita Y Watanabe H, Ishibashi K, Mano H, Kitamoto S, Sato N, Hoshiba K, Kato M, Matsuzawa F, Takeuchi Y, Shirai T, Ishikawa S, Morioka Y, Imagawa T, Sakaguchi K, Yonezawa S, Kon S, Fujita Y Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells. Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells. Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells. Cell reports, 23, 13, 3721-3729 Cell reports, 23, 13, 3721-3729 Cell reports, 23, 13, 3721-3729 2018/06 公開
Sasaki A, Nagatake T, Egami R, Gu G, Takigawa I, Ikeda W, Nakatani T, Kunisawa J, Fujita Y Sasaki A, Nagatake T, Egami R, Gu G, Takigawa I, Ikeda W, Nakatani T, Kunisawa J, Fujita Y Sasaki A, Nagatake T, Egami R, Gu G, Takigawa I, Ikeda W, Nakatani T, Kunisawa J, Fujita Y Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues. Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues. Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues. Cell reports, 23, 4, 974-982 Cell reports, 23, 4, 974-982 Cell reports, 23, 4, 974-982 2018/04 公開
Kasai N, Kadeer A, Kajita M, Saitoh S, Ishikawa S, Maruyama T, Fujita Y Kasai N, Kadeer A, Kajita M, Saitoh S, Ishikawa S, Maruyama T, Fujita Y Kasai N, Kadeer A, Kajita M, Saitoh S, Ishikawa S, Maruyama T, Fujita Y The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. Scientific reports, 8, 1, 2097 Scientific reports, 8, 1, 2097 Scientific reports, 8, 1, 2097 2018/02 公開
Anna Bove, Daniel Gradeci, Yasuyuki Fujita, Shiladitya Banerjee, Guillaume Charras, Alan R. Lowe Anna Bove, Daniel Gradeci, Yasuyuki Fujita, Shiladitya Banerjee, Guillaume Charras, Alan R. Lowe Anna Bove, Daniel Gradeci, Yasuyuki Fujita, Shiladitya Banerjee, Guillaume Charras, Alan R. Lowe Local cellular neighborhood controls proliferation in cell competition Local cellular neighborhood controls proliferation in cell competition Local cellular neighborhood controls proliferation in cell competition MOLECULAR BIOLOGY OF THE CELL, 28, 23, 3215-3228 MOLECULAR BIOLOGY OF THE CELL, 28, 23, 3215-3228 MOLECULAR BIOLOGY OF THE CELL, 28, 23, 3215-3228 2017/11 英語 研究論文(学術雑誌) 公開
Takeshi Maruyama, Yasuyuki Fujita Takeshi Maruyama, Yasuyuki Fujita Takeshi Maruyama, Yasuyuki Fujita Cell competition in mammals - novel homeostatic machinery for embryonic development and cancer prevention Cell competition in mammals - novel homeostatic machinery for embryonic development and cancer prevention Cell competition in mammals - novel homeostatic machinery for embryonic development and cancer prevention CURRENT OPINION IN CELL BIOLOGY, 48, 106-112 CURRENT OPINION IN CELL BIOLOGY, 48, 106-112 CURRENT OPINION IN CELL BIOLOGY, 48, 106-112 2017/10 英語 研究論文(学術雑誌) 公開
Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y Shunsuke Kon, Kojiro Ishibashi, Hiroto Katoh, Sho Kitamoto, Takanobu Shirai, Shinya Tanaka, Mihoko Kajita, Susumu Ishikawa, Hajime Yamauchi, Yuta Yako, Tomoko Kamasaki, Tomohiro Matsumoto, Hirotaka Watanabe, Riku Egami, Ayana Sasaki, Atsuko Nishikawa, Ikumi Kameda, Takeshi Maruyama, Rika Narumi, Tomoko Morita, Yoshiteru Sasaki, Ryosuke Enoki, Sato Honma, Hiromi Imamura, Masanobu Oshima, Tomoyoshi Soga, Jun-ichi Miyazaki, Michael R. Duchen, Jin-Min Nam, Yasuhito Onodera, Shingo Yoshioka, Junichi Kikuta, Masaru Ishii, Masamichi Imajo, Eisuke Nishida, Yoichiro Fujioka, Yusuke Ohba, Toshiro Sato, Yasuyuki Fujita Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes. Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes. Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes Nature cell biology, 19, 5, 530-+ Nature cell biology, 19, 5, 530-+ NATURE CELL BIOLOGY, 19, 5, 530-+ 2017/05 英語 研究論文(学術雑誌) 公開
Sayaka Saitoh, Takeshi Maruyama, Yuta Yako, Mihoko Kajita, Yoichiro Fujioka, Yusuke Ohba, Nobuhiro Kasai, Natsu Sugama, Shunsuke Kon, Susumu Ishikawa, Takashi Hayashi, Tomohiro Yamazaki, Masazumi Tada, Yasuyuki Fujita Sayaka Saitoh, Takeshi Maruyama, Yuta Yako, Mihoko Kajita, Yoichiro Fujioka, Yusuke Ohba, Nobuhiro Kasai, Natsu Sugama, Shunsuke Kon, Susumu Ishikawa, Takashi Hayashi, Tomohiro Yamazaki, Masazumi Tada, Yasuyuki Fujita Sayaka Saitoh, Takeshi Maruyama, Yuta Yako, Mihoko Kajita, Yoichiro Fujioka, Yusuke Ohba, Nobuhiro Kasai, Natsu Sugama, Shunsuke Kon, Susumu Ishikawa, Takashi Hayashi, Tomohiro Yamazaki, Masazumi Tada, Yasuyuki Fujita Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 12, E2327-E2336 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 12, E2327-E2336 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114, 12, E2327-E2336 2017/03 英語 研究論文(学術雑誌) 公開
Ailijiang Kadeer, Takeshi Maruyama, Mihoko Kajita, Tomoko Morita, Ayana Sasaki, Atsuko Ohoka, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Ailijiang Kadeer, Takeshi Maruyama, Mihoko Kajita, Tomoko Morita, Ayana Sasaki, Atsuko Ohoka, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Ailijiang Kadeer, Takeshi Maruyama, Mihoko Kajita, Tomoko Morita, Ayana Sasaki, Atsuko Ohoka, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Plectin is a novel regulator for apical extrusion of RasV12-transformed cells Plectin is a novel regulator for apical extrusion of RasV12-transformed cells Plectin is a novel regulator for apical extrusion of RasV12-transformed cells SCIENTIFIC REPORTS, 7, 44328 SCIENTIFIC REPORTS, 7, 44328 SCIENTIFIC REPORTS, 7, 44328 2017/03 英語 研究論文(学術雑誌) 公開
藤田 恭之 藤田 恭之 Fujita Yasuyuki The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation. 2017 公開
Sean Porazinski, Joaquin de Navascues, Yuta Yako, William Hill, Matthew Robert Jones, Robert Maddison, Yasuyuki Fujita, Catherine Hogan Sean Porazinski, Joaquin de Navascues, Yuta Yako, William Hill, Matthew Robert Jones, Robert Maddison, Yasuyuki Fujita, Catherine Hogan Sean Porazinski, Joaquin de Navascues, Yuta Yako, William Hill, Matthew Robert Jones, Robert Maddison, Yasuyuki Fujita, Catherine Hogan EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors CURRENT BIOLOGY, 26, 23, 3220-3229 CURRENT BIOLOGY, 26, 23, 3220-3229 CURRENT BIOLOGY, 26, 23, 3220-3229 2016/12 英語 研究論文(学術雑誌) 公開
Takanori Chiba, Erika Ishihara, Norio Miyamura, Rika Narumi, Mihoko Kajita, Yasuyuki Fujita, Akira Suzuki, Yoshihiro Ogawa, Hiroshi Nishina Takanori Chiba, Erika Ishihara, Norio Miyamura, Rika Narumi, Mihoko Kajita, Yasuyuki Fujita, Akira Suzuki, Yoshihiro Ogawa, Hiroshi Nishina Takanori Chiba, Erika Ishihara, Norio Miyamura, Rika Narumi, Mihoko Kajita, Yasuyuki Fujita, Akira Suzuki, Yoshihiro Ogawa, Hiroshi Nishina MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status SCIENTIFIC REPORTS, 6, 28383 SCIENTIFIC REPORTS, 6, 28383 SCIENTIFIC REPORTS, 6, 28383 2016/06 英語 研究論文(学術雑誌) 公開
Sayaka Yamamoto, Yuta Yako, Yoichiro Fujioka, Mihoko Kajita, Takeshi Kameyama, Shunsuke Kon, Susumu Ishikawa, Yusuke Ohba, Yusuke Ohno, Akio Kihara, Yasuyuki Fujita Sayaka Yamamoto, Yuta Yako, Yoichiro Fujioka, Mihoko Kajita, Takeshi Kameyama, Shunsuke Kon, Susumu Ishikawa, Yusuke Ohba, Yusuke Ohno, Akio Kihara, Yasuyuki Fujita Sayaka Yamamoto, Yuta Yako, Yoichiro Fujioka, Mihoko Kajita, Takeshi Kameyama, Shunsuke Kon, Susumu Ishikawa, Yusuke Ohba, Yusuke Ohno, Akio Kihara, Yasuyuki Fujita A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC). Molecular biology of the cell, 27, 3, 491-9 Molecular biology of the cell, 27, 3, 491-9 Molecular biology of the cell, 27, 3, 491-9 2016/02/01 英語 公開
Hajime Yamauchi, Takanori Matsumaru, Tomoko Morita, Susumu Ishikawa, Katsumi Maenaka, Ichigaku Takigawa, Kentaro Semba, Shunsuke Kon, Yasuyuki Fujita Hajime Yamauchi, Takanori Matsumaru, Tomoko Morita, Susumu Ishikawa, Katsumi Maenaka, Ichigaku Takigawa, Kentaro Semba, Shunsuke Kon, Yasuyuki Fujita Hajime Yamauchi, Takanori Matsumaru, Tomoko Morita, Susumu Ishikawa, Katsumi Maenaka, Ichigaku Takigawa, Kentaro Semba, Shunsuke Kon, Yasuyuki Fujita The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia The cell competition-based high-throughput screening identifies small compounds that promote the elimination of RasV12-transformed cells from epithelia SCIENTIFIC REPORTS, 5, 15336 SCIENTIFIC REPORTS, 5, 15336 SCIENTIFIC REPORTS, 5, 15336 2015/10 英語 研究論文(学術雑誌) 公開
Mihoko Kajita, Yasuyuki Fujita Mihoko Kajita, Yasuyuki Fujita Mihoko Kajita, Yasuyuki Fujita EDAC: Epithelial defence against cancer-cell competition between normal and transformed epithelial cells in mammals EDAC: Epithelial defence against cancer-cell competition between normal and transformed epithelial cells in mammals EDAC: Epithelial defence against cancer-cell competition between normal and transformed epithelial cells in mammals JOURNAL OF BIOCHEMISTRY, 158, 1, 15-23 JOURNAL OF BIOCHEMISTRY, 158, 1, 15-23 JOURNAL OF BIOCHEMISTRY, 158, 1, 15-23 2015/07 英語 公開
Atsuko Ohoka, Mihoko Kajita, Junichi Ikenouchi, Yuta Yako, Sho Kitamoto, Shunsuke Kon, Masaya Ikegawa, Takashi Shimada, Susumu Ishikawa, Yasuyuki Fujita Atsuko Ohoka, Mihoko Kajita, Junichi Ikenouchi, Yuta Yako, Sho Kitamoto, Shunsuke Kon, Masaya Ikegawa, Takashi Shimada, Susumu Ishikawa, Yasuyuki Fujita Atsuko Ohoka, Mihoko Kajita, Junichi Ikenouchi, Yuta Yako, Sho Kitamoto, Shunsuke Kon, Masaya Ikegawa, Takashi Shimada, Susumu Ishikawa, Yasuyuki Fujita EPLIN is a crucial regulator for extrusion of RasV12-transformed cells EPLIN is a crucial regulator for extrusion of RasV12-transformed cells EPLIN is a crucial regulator for extrusion of RasV12-transformed cells JOURNAL OF CELL SCIENCE, 128, 4, 781-789 JOURNAL OF CELL SCIENCE, 128, 4, 781-789 JOURNAL OF CELL SCIENCE, 128, 4, 781-789 2015/02 英語 研究論文(学術雑誌) 公開
Laura P. Ivers, Brendan Cummings, Funke Owolabi, Katarzyna Welzel, Rut Klinger, Sayaka Saitoh, Darran O'Connor, Yasuyuki Fujita, Dimitri Scholz, Nobue Itasaki Laura P. Ivers, Brendan Cummings, Funke Owolabi, Katarzyna Welzel, Rut Klinger, Sayaka Saitoh, Darran O'Connor, Yasuyuki Fujita, Dimitri Scholz, Nobue Itasaki Laura P. Ivers, Brendan Cummings, Funke Owolabi, Katarzyna Welzel, Rut Klinger, Sayaka Saitoh, Darran O'Connor, Yasuyuki Fujita, Dimitri Scholz, Nobue Itasaki Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture CANCER CELL INTERNATIONAL, 14, 1, 108 CANCER CELL INTERNATIONAL, 14, 1, 108 CANCER CELL INTERNATIONAL, 14, 1, 108 2014/10 英語 研究論文(学術雑誌) 公開
Katarzyna A. Anton, John Sinclair, Atsuko Ohoka, Mihoko Kajita, Susumu Ishikawa, Peter M. Benz, Thomas Renne, Maria Balda, Claus Jorgensen, Karl Matter, Yasuyuki Fujita Katarzyna A. Anton, John Sinclair, Atsuko Ohoka, Mihoko Kajita, Susumu Ishikawa, Peter M. Benz, Thomas Renne, Maria Balda, Claus Jorgensen, Karl Matter, Yasuyuki Fujita Katarzyna A. Anton, John Sinclair, Atsuko Ohoka, Mihoko Kajita, Susumu Ishikawa, Peter M. Benz, Thomas Renne, Maria Balda, Claus Jorgensen, Karl Matter, Yasuyuki Fujita PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium JOURNAL OF CELL SCIENCE, 127, 16, 3425-3433 JOURNAL OF CELL SCIENCE, 127, 16, 3425-3433 JOURNAL OF CELL SCIENCE, 127, 16, 3425-3433 2014/08 英語 研究論文(学術雑誌) 公開
Mihoko Kajita, Kaoru Sugimura, Atsuko Ohoka, Jemima Burden, Hitomi Suganuma, Masaya Ikegawa, Takashi Shimada, Tetsuya Kitamura, Masanobu Shindoh, Susumu Ishikawa, Sayaka Yamamoto, Sayaka Saitoh, Yuta Yako, Ryosuke Takahashi, Takaharu Okajima, Junichi Kikuta, Yumiko Maijima, Masaru Ishii, Masazumi Tada, Yasuyuki Fujita Mihoko Kajita, Kaoru Sugimura, Atsuko Ohoka, Jemima Burden, Hitomi Suganuma, Masaya Ikegawa, Takashi Shimada, Tetsuya Kitamura, Masanobu Shindoh, Susumu Ishikawa, Sayaka Yamamoto, Sayaka Saitoh, Yuta Yako, Ryosuke Takahashi, Takaharu Okajima, Junichi Kikuta, Yumiko Maijima, Masaru Ishii, Masazumi Tada, Yasuyuki Fujita Mihoko Kajita, Kaoru Sugimura, Atsuko Ohoka, Jemima Burden, Hitomi Suganuma, Masaya Ikegawa, Takashi Shimada, Tetsuya Kitamura, Masanobu Shindoh, Susumu Ishikawa, Sayaka Yamamoto, Sayaka Saitoh, Yuta Yako, Ryosuke Takahashi, Takaharu Okajima, Junichi Kikuta, Yumiko Maijima, Masaru Ishii, Masazumi Tada, Yasuyuki Fujita Filamin acts as a key regulator in epithelial defence against transformed cells Filamin acts as a key regulator in epithelial defence against transformed cells Filamin acts as a key regulator in epithelial defence against transformed cells NATURE COMMUNICATIONS, 5, 4428 NATURE COMMUNICATIONS, 5, 4428 NATURE COMMUNICATIONS, 5, 4428 2014/07 英語 研究論文(学術雑誌) 公開
Dorothy Kuipers, Aida Mehonic, Mihoko Kajita, Loic Peter, Yasuyuki Fujita, Tom Duke, Guillaume Charras, Jonathan E. Gale Dorothy Kuipers, Aida Mehonic, Mihoko Kajita, Loic Peter, Yasuyuki Fujita, Tom Duke, Guillaume Charras, Jonathan E. Gale Dorothy Kuipers, Aida Mehonic, Mihoko Kajita, Loic Peter, Yasuyuki Fujita, Tom Duke, Guillaume Charras, Jonathan E. Gale Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours JOURNAL OF CELL SCIENCE, 127, 6, 1229-1241 JOURNAL OF CELL SCIENCE, 127, 6, 1229-1241 JOURNAL OF CELL SCIENCE, 127, 6, 1229-1241 2014/03 英語 研究論文(学術雑誌) 公開
Alexandre Benedetto, Giovanni Accetta, Yasuyuki Fujita, Guillaume Charras Alexandre Benedetto, Giovanni Accetta, Yasuyuki Fujita, Guillaume Charras Alexandre Benedetto, Giovanni Accetta, Yasuyuki Fujita, Guillaume Charras Spatiotemporal control of gene expression using microfluidics Spatiotemporal control of gene expression using microfluidics Spatiotemporal control of gene expression using microfluidics LAB ON A CHIP, 14, 7, 1336-1347 LAB ON A CHIP, 14, 7, 1336-1347 LAB ON A CHIP, 14, 7, 1336-1347 2014 英語 研究論文(学術雑誌) 公開
Masao Saitoh, Takuya Shirakihara, Akira Fukasawa, Kana Horiguchi, Kei Sakamoto, Hiroshi Sugiya, Hideyuki Beppu, Yasuyuki Fujita, Ikuo Morita, Kohei Miyazono, Keiji Miyazawa Masao Saitoh, Takuya Shirakihara, Akira Fukasawa, Kana Horiguchi, Kei Sakamoto, Hiroshi Sugiya, Hideyuki Beppu, Yasuyuki Fujita, Ikuo Morita, Kohei Miyazono, Keiji Miyazawa Masao Saitoh, Takuya Shirakihara, Akira Fukasawa, Kana Horiguchi, Kei Sakamoto, Hiroshi Sugiya, Hideyuki Beppu, Yasuyuki Fujita, Ikuo Morita, Kohei Miyazono, Keiji Miyazawa Basolateral BMP Signaling in Polarized Epithelial Cells Basolateral BMP Signaling in Polarized Epithelial Cells Basolateral BMP Signaling in Polarized Epithelial Cells PLOS ONE, 8, 5, e62659 PLOS ONE, 8, 5, e62659 PLOS ONE, 8, 5, e62659 2013/05 英語 研究論文(学術雑誌) 公開
梶田美穂子, 藤田恭之 梶田美穂子, 藤田恭之 Kajita, M, Fujita, Y Competition between normal anc transformed epithelial cells-a novel dimension of cancer heterogeneity Competition between normal anc transformed epithelial cells-a novel dimension of cancer heterogeneity Competition between normal anc transformed epithelial cells-a novel dimension of cancer heterogeneity 実験医学, 31, 1, 39-44 実験医学, 31, 1, 39-44 Jikkenigaku, 31, 1, 39-44 2013/01 日本語 公開
Hajime Yamauchi, Yasuyuki Fujita Hajime Yamauchi, Yasuyuki Fujita Hajime Yamauchi, Yasuyuki Fujita Epithelial self-defense against cancer Epithelial self-defense against cancer Epithelial self-defense against cancer CELL RESEARCH, 22, 11, 1527-1529 CELL RESEARCH, 22, 11, 1527-1529 CELL RESEARCH, 22, 11, 1527-1529 2012/11 英語 公開
Kajita M, Fujita Y Kajita M, Fujita Y Kajita M, Fujita Y [Interactions between normal and transformed epithelial cells: their clinical applications]. [Interactions between normal and transformed epithelial cells: their clinical applications]. [Interactions between normal and transformed epithelial cells: their clinical applications]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 140, 2, 76-80 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 140, 2, 76-80 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 140, 2, 76-80 2012/08 公開
Hiroto Katoh, Yasuyuki Fujita Hiroto Katoh, Yasuyuki Fujita Hiroto Katoh, Yasuyuki Fujita Epithelial Homeostasis: Elimination by Live Cell Extrusion Epithelial Homeostasis: Elimination by Live Cell Extrusion Epithelial Homeostasis: Elimination by Live Cell Extrusion CURRENT BIOLOGY, 22, 11, R453-R455 CURRENT BIOLOGY, 22, 11, R453-R455 CURRENT BIOLOGY, 22, 11, R453-R455 2012/06 英語 公開
Mark Norman, Katarzyna A. Wisniewska, Kate Lawrenson, Pablo Garcia-Miranda, Masazumi Tada, Mihoko Kajita, Hiroki Mano, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Mark Norman, Katarzyna A. Wisniewska, Kate Lawrenson, Pablo Garcia-Miranda, Masazumi Tada, Mihoko Kajita, Hiroki Mano, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Mark Norman, Katarzyna A. Wisniewska, Kate Lawrenson, Pablo Garcia-Miranda, Masazumi Tada, Mihoko Kajita, Hiroki Mano, Susumu Ishikawa, Masaya Ikegawa, Takashi Shimada, Yasuyuki Fujita Loss of Scribble causes cell competition in mammalian cells Loss of Scribble causes cell competition in mammalian cells Loss of Scribble causes cell competition in mammalian cells JOURNAL OF CELL SCIENCE, 125, 1, 59-66 JOURNAL OF CELL SCIENCE, 125, 1, 59-66 JOURNAL OF CELL SCIENCE, 125, 1, 59-66 2012/01 英語 研究論文(学術雑誌) 公開
Yasuyuki Fujita Yasuyuki Fujita Yasuyuki Fujita Interface between normal and transformed epithelial cells: A road to a novel type of cancer prevention and treatment Interface between normal and transformed epithelial cells: A road to a novel type of cancer prevention and treatment Interface between normal and transformed epithelial cells: A road to a novel type of cancer prevention and treatment CANCER SCIENCE, 102, 10, 1749-1755 CANCER SCIENCE, 102, 10, 1749-1755 CANCER SCIENCE, 102, 10, 1749-1755 2011/10 英語 公開
Howard S, Deroo T, Fujita Y, Itasaki N Howard S, Deroo T, Fujita Y, Itasaki N Sara Howard, Tom Deroo, Yasuyuki Fujita, Nobue Itasaki A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition. A positive role of cadherin in Wnt/β-catenin signalling during epithelial-mesenchymal transition. A Positive Role of Cadherin in Wnt/beta-Catenin Signalling during Epithelial-Mesenchymal Transition PloS one, 6, 8, e23899 PloS one, 6, 8, e23899 PLOS ONE, 6, 8, e23899 2011/08 英語 研究論文(学術雑誌) 公開
Catherine Hogan, Mihoko Kajita, Kate Lawrenson, Yasuyuki Fujita Catherine Hogan, Mihoko Kajita, Kate Lawrenson, Yasuyuki Fujita Catherine Hogan, Mihoko Kajita, Kate Lawrenson, Yasuyuki Fujita Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 43, 4, 496-503 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 43, 4, 496-503 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 43, 4, 496-503 2011/04 英語 公開
Sophie Dupre-Crochet, Catherine Hogan, Yasuyuki Fujita Sophie Dupre-Crochet, Catherine Hogan, Yasuyuki Fujita Sophie Dupre-Crochet, Catherine Hogan, Yasuyuki Fujita Interactions between normal and transformed epithelial cells Interactions between normal and transformed epithelial cells Interactions between normal and transformed epithelial cells M S-MEDECINE SCIENCES, 26, 5, 457-458 M S-MEDECINE SCIENCES, 26, 5, 457-458 M S-MEDECINE SCIENCES, 26, 5, 457-458 2010/05 フランス語 公開
Mihoko Kajita, Catherine Hogan, Andrew R. Harris, Sophie Dupre-Crochet, Nobue Itasaki, Koichi Kawakami, Guillaume Charras, Masazumi Tada, Yasuyuki Fujita Mihoko Kajita, Catherine Hogan, Andrew R. Harris, Sophie Dupre-Crochet, Nobue Itasaki, Koichi Kawakami, Guillaume Charras, Masazumi Tada, Yasuyuki Fujita Mihoko Kajita, Catherine Hogan, Andrew R. Harris, Sophie Dupre-Crochet, Nobue Itasaki, Koichi Kawakami, Guillaume Charras, Masazumi Tada, Yasuyuki Fujita Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells JOURNAL OF CELL SCIENCE, 123, 2, 171-180 JOURNAL OF CELL SCIENCE, 123, 2, 171-180 JOURNAL OF CELL SCIENCE, 123, 2, 171-180 2010/01 英語 研究論文(学術雑誌) 公開
Fujita Y, Kajita M Fujita Y, Kajita M Fujita Y, Kajita M [Interface between normal and transformed epithelial cells]. [Interface between normal and transformed epithelial cells]. [Interface between normal and transformed epithelial cells]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 55, 48-54 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 55, 48-54 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 55, 48-54 2010/01 公開
Angelica Figueroa, Yasuyuki Fujita, Myriam Gorospe Angelica Figueroa, Yasuyuki Fujita, Myriam Gorospe Angelica Figueroa, Yasuyuki Fujita, Myriam Gorospe Hacking RNA Hakai promotes tumorigenesis by enhancing the RNA-binding function of PSF Hacking RNA Hakai promotes tumorigenesis by enhancing the RNA-binding function of PSF Hacking RNA Hakai promotes tumorigenesis by enhancing the RNA-binding function of PSF CELL CYCLE, 8, 22, 3648-3651 CELL CYCLE, 8, 22, 3648-3651 CELL CYCLE, 8, 22, 3648-3651 2009/11 英語 研究論文(学術雑誌) 公開
Angelica Figueroa, Hirokazu Kotani, Yoshinobu Toda, Krystyna Mazan-Mamczarz, Eva-Christina Mueller, Albrecht Otto, Lena Disch, Mark Norman, Rasika Mohan Ramdasi, Mohammed Keshtgar, Myriam Gorospe, Yasuyuki Fujita Angelica Figueroa, Hirokazu Kotani, Yoshinobu Toda, Krystyna Mazan-Mamczarz, Eva-Christina Mueller, Albrecht Otto, Lena Disch, Mark Norman, Rasika Mohan Ramdasi, Mohammed Keshtgar, Myriam Gorospe, Yasuyuki Fujita Angelica Figueroa, Hirokazu Kotani, Yoshinobu Toda, Krystyna Mazan-Mamczarz, Eva-Christina Mueller, Albrecht Otto, Lena Disch, Mark Norman, Rasika Mohan Ramdasi, Mohammed Keshtgar, Myriam Gorospe, Yasuyuki Fujita Novel Roles of Hakai in Cell Proliferation and Oncogenesis Novel Roles of Hakai in Cell Proliferation and Oncogenesis Novel Roles of Hakai in Cell Proliferation and Oncogenesis MOLECULAR BIOLOGY OF THE CELL, 20, 15, 3533-3542 MOLECULAR BIOLOGY OF THE CELL, 20, 15, 3533-3542 MOLECULAR BIOLOGY OF THE CELL, 20, 15, 3533-3542 2009/08 英語 研究論文(学術雑誌) 公開
Catherine Hogan, Sophie Dupre-Crochet, Mark Norman, Mihoko Kajita, Carola Zimmermann, Andrew E. Pelling, Eugenia Piddini, Luis Alberto Baena-Lopez, Jean-Paul Vincent, Yoshifumi Itoh, Hiroshi Hosoya, Franck Pichaud, Yasuyuki Fujita Catherine Hogan, Sophie Dupre-Crochet, Mark Norman, Mihoko Kajita, Carola Zimmermann, Andrew E. Pelling, Eugenia Piddini, Luis Alberto Baena-Lopez, Jean-Paul Vincent, Yoshifumi Itoh, Hiroshi Hosoya, Franck Pichaud, Yasuyuki Fujita Catherine Hogan, Sophie Dupre-Crochet, Mark Norman, Mihoko Kajita, Carola Zimmermann, Andrew E. Pelling, Eugenia Piddini, Luis Alberto Baena-Lopez, Jean-Paul Vincent, Yoshifumi Itoh, Hiroshi Hosoya, Franck Pichaud, Yasuyuki Fujita Characterization of the interface between normal and transformed epithelial cells Characterization of the interface between normal and transformed epithelial cells Characterization of the interface between normal and transformed epithelial cells NATURE CELL BIOLOGY, 11, 4, 460-U234 NATURE CELL BIOLOGY, 11, 4, 460-U234 NATURE CELL BIOLOGY, 11, 4, 460-U234 2009/04 英語 研究論文(学術雑誌) 公開
Kajita M, Fujita Y Kajita M, Fujita Y Kajita M, Fujita Y [Interaction between normal and transformed epithelial cells]. [Interaction between normal and transformed epithelial cells]. [Interaction between normal and transformed epithelial cells]. Seikagaku. The Journal of Japanese Biochemical Society, 81, 267-276 Seikagaku. The Journal of Japanese Biochemical Society, 81, 267-276 Seikagaku. The Journal of Japanese Biochemical Society, 81, 267-276 2009/04 公開
Filipa Carreira-Barbosa, Mihiko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Filipa Carreira-Barbosa, Mihiko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Filipa Carreira-Barbosa, Mihiko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation DEVELOPMENT, 136, 3, 383-392 DEVELOPMENT, 136, 3, 383-392 DEVELOPMENT, 136, 3, 383-392 2009/02 英語 研究論文(学術雑誌) 公開
Emma C. Ferber, Mihoko Kajita, Anthony Wadlow, Lara Tobiansky, Carien Niessen, Hiroyoshi Ariga, Juliet Daniel, Yasuyuki Fujita Emma C. Ferber, Mihoko Kajita, Anthony Wadlow, Lara Tobiansky, Carien Niessen, Hiroyoshi Ariga, Juliet Daniel, Yasuyuki Fujita Emma C. Ferber, Mihoko Kajita, Anthony Wadlow, Lara Tobiansky, Carien Niessen, Hiroyoshi Ariga, Juliet Daniel, Yasuyuki Fujita A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus JOURNAL OF BIOLOGICAL CHEMISTRY, 283, 19, 12691-12700 JOURNAL OF BIOLOGICAL CHEMISTRY, 283, 19, 12691-12700 JOURNAL OF BIOLOGICAL CHEMISTRY, 283, 19, 12691-12700 2008/05 英語 研究論文(学術雑誌) 公開
Carl U. Bialucha, Emma C. Ferber, Franck Pichaud, Sew Y. Peak-Chew, Yasuyuki Fujita Carl U. Bialucha, Emma C. Ferber, Franck Pichaud, Sew Y. Peak-Chew, Yasuyuki Fujita Carl U. Bialucha, Emma C. Ferber, Franck Pichaud, Sew Y. Peak-Chew, Yasuyuki Fujita p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase C zeta and regulates cell polarity p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase C zeta and regulates cell polarity p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase C zeta and regulates cell polarity JOURNAL OF CELL BIOLOGY, 178, 4, 575-581 JOURNAL OF CELL BIOLOGY, 178, 4, 575-581 JOURNAL OF CELL BIOLOGY, 178, 4, 575-581 2007/08 英語 研究論文(学術雑誌) 公開
Catherine Rose Hosking, Fausto Ulloa, Catherine Hogan, Emma C. Ferber, Anglica Figueroa, Kris Gevaert, Walter Birchmeier, James Briscoe, Yasuyuki Fujita Catherine Rose Hosking, Fausto Ulloa, Catherine Hogan, Emma C. Ferber, Anglica Figueroa, Kris Gevaert, Walter Birchmeier, James Briscoe, Yasuyuki Fujita Catherine Rose Hosking, Fausto Ulloa, Catherine Hogan, Emma C. Ferber, Anglica Figueroa, Kris Gevaert, Walter Birchmeier, James Briscoe, Yasuyuki Fujita The transcriptional repressor Glis2 is a novel binding partner for p120 catenin The transcriptional repressor Glis2 is a novel binding partner for p120 catenin The transcriptional repressor Glis2 is a novel binding partner for p120 catenin MOLECULAR BIOLOGY OF THE CELL, 18, 5, 1918-1927 MOLECULAR BIOLOGY OF THE CELL, 18, 5, 1918-1927 MOLECULAR BIOLOGY OF THE CELL, 18, 5, 1918-1927 2007/05 英語 研究論文(学術雑誌) 公開
Sophie Dupre-Crochet, Angelica Figueroa, Catherine Hogan, Emma C. Ferber, Carl Uli Bialucha, Joanna Adams, Emily C. N. Richardson, Yasuyuki Fujita Sophie Dupre-Crochet, Angelica Figueroa, Catherine Hogan, Emma C. Ferber, Carl Uli Bialucha, Joanna Adams, Emily C. N. Richardson, Yasuyuki Fujita Sophie Dupre-Crochet, Angelica Figueroa, Catherine Hogan, Emma C. Ferber, Carl Uli Bialucha, Joanna Adams, Emily C. N. Richardson, Yasuyuki Fujita Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts MOLECULAR AND CELLULAR BIOLOGY, 27, 10, 3804-3816 MOLECULAR AND CELLULAR BIOLOGY, 27, 10, 3804-3816 MOLECULAR AND CELLULAR BIOLOGY, 27, 10, 3804-3816 2007/05 英語 研究論文(学術雑誌) 公開
N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud Regulated and polarized Ptdlns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells Regulated and polarized Ptdlns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells Regulated and polarized Ptdlns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells CURRENT BIOLOGY, 16, 2, 140-149 CURRENT BIOLOGY, 16, 2, 140-149 CURRENT BIOLOGY, 16, 2, 140-149 2006/01 英語 研究論文(学術雑誌) 公開
Yasuyuki Fujita, Catherine Hogan, Vania M. M. Braga Yasuyuki Fujita, Catherine Hogan, Vania M. M. Braga Yasuyuki Fujita, Catherine Hogan, Vania M. M. Braga Regulation of cell-cell adhesion by Rap1 Regulation of cell-cell adhesion by Rap1 Regulation of cell-cell adhesion by Rap1 REGULATORS AND EFFECTORS OF SMALL GTPASES: RAS FAMILY, 407, 359-+ REGULATORS AND EFFECTORS OF SMALL GTPASES: RAS FAMILY, 407, 359-+ REGULATORS AND EFFECTORS OF SMALL GTPASES: RAS FAMILY, 407, 359-+ 2006 英語 公開
F Palacios, JS Tushir, Y Fujita, C D'Souza-Schorey F Palacios, JS Tushir, Y Fujita, C D'Souza-Schorey F Palacios, JS Tushir, Y Fujita, C D'Souza-Schorey Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 389-402 MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 389-402 MOLECULAR AND CELLULAR BIOLOGY, 25, 1, 389-402 2005/01 英語 研究論文(学術雑誌) 公開
Fujita Y, Braga V Fujita Y, Braga V Fujita Y, Braga V Epithelial cell shape and Rho small GTPases. Epithelial cell shape and Rho small GTPases. Epithelial cell shape and Rho small GTPases. Novartis Foundation symposium, 269, 144-55; discussion 155 Novartis Foundation symposium, 269, 144-55; discussion 155 Novartis Foundation symposium, 269, 144-55; discussion 155 2005 公開
C Hogan, N Serpente, P Cogram, CR Hosking, CU Bialucha, SM Feller, VMM Braga, W Birchmeier, Y Fujita C Hogan, N Serpente, P Cogram, CR Hosking, CU Bialucha, SM Feller, VMM Braga, W Birchmeier, Y Fujita C Hogan, N Serpente, P Cogram, CR Hosking, CU Bialucha, SM Feller, VMM Braga, W Birchmeier, Y Fujita Rap1 regulates the formation of E-cadherin-based cell-cell contacts Rap1 regulates the formation of E-cadherin-based cell-cell contacts Rap1 regulates the formation of E-cadherin-based cell-cell contacts MOLECULAR AND CELLULAR BIOLOGY, 24, 15, 6690-6700 MOLECULAR AND CELLULAR BIOLOGY, 24, 15, 6690-6700 MOLECULAR AND CELLULAR BIOLOGY, 24, 15, 6690-6700 2004/08 英語 研究論文(学術雑誌) 公開
M Yanagisawa, IN Kaverina, AX Wang, Y Fujita, AB Reynolds, PZ Anastasiadis M Yanagisawa, IN Kaverina, AX Wang, Y Fujita, AB Reynolds, PZ Anastasiadis M Yanagisawa, IN Kaverina, AX Wang, Y Fujita, AB Reynolds, PZ Anastasiadis A novel interaction between kinesin and p120 modulates p120 localization and function A novel interaction between kinesin and p120 modulates p120 localization and function A novel interaction between kinesin and p120 modulates p120 localization and function JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 10, 9512-9521 JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 10, 9512-9521 JOURNAL OF BIOLOGICAL CHEMISTRY, 279, 10, 9512-9521 2004/03 英語 研究論文(学術雑誌) 公開
D Zechner, Y Fujita, J Hulsken, T Muller, Walther, I, MM Taketo, EB Crenshaw, W Birchmeier, C Birchmeier D Zechner, Y Fujita, J Hulsken, T Muller, Walther, I, MM Taketo, EB Crenshaw, W Birchmeier, C Birchmeier D Zechner, Y Fujita, J Hulsken, T Muller, Walther, I, MM Taketo, EB Crenshaw, W Birchmeier, C Birchmeier beta-catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system beta-catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system beta-catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system DEVELOPMENTAL BIOLOGY, 258, 2, 406-418 DEVELOPMENTAL BIOLOGY, 258, 2, 406-418 DEVELOPMENTAL BIOLOGY, 258, 2, 406-418 2003/06 英語 研究論文(学術雑誌) 公開
Y Fujita, G Krause, M Scheffner, D Zechner, HEM Leddy, J Behrens, T Sommer, W Birchmeier Y Fujita, G Krause, M Scheffner, D Zechner, HEM Leddy, J Behrens, T Sommer, W Birchmeier Y Fujita, G Krause, M Scheffner, D Zechner, HEM Leddy, J Behrens, T Sommer, W Birchmeier Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex NATURE CELL BIOLOGY, 4, 3, 222-231 NATURE CELL BIOLOGY, 4, 3, 222-231 NATURE CELL BIOLOGY, 4, 3, 222-231 2002/03 英語 研究論文(学術雑誌) 公開
Fujita Yasuyuki Fujita Yasuyuki Fujita Yasuyuki The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
梶田 美穂子, 藤田 恭之 梶田 美穂子, 藤田 恭之 KAJITA Mihoko, FUJITA Yasuyuki 正常上皮細胞と変異上皮細胞間の相互作用とその臨床応用 正常上皮細胞と変異上皮細胞間の相互作用とその臨床応用 Interactions between normal and transformed epithelial cells : their clinical applications 日本薬理學雜誌 = Folia pharmacologica Japonica, 140, 2, 76-80 日本薬理學雜誌 = Folia pharmacologica Japonica, 140, 2, 76-80 Folia Pharmacologica Japonica, 140, 2, 76-80 2012/08/01 日本語 公開
FUJITA Yasuyuki FUJITA Yasuyuki FUJITA Yasuyuki Interface between normal and transformed epithelial cells : A road to a novel type of cancer prevention and treatment Interface between normal and transformed epithelial cells : A road to a novel type of cancer prevention and treatment Interface between normal and transformed epithelial cells : A road to a novel type of cancer prevention and treatment Cancer science, 102, 10, 1749-1755 Cancer science, 102, 10, 1749-1755 Cancer Science, 102, 10, 1749-1755 2011/10/10 英語 公開
田守 洋一郎, 藤田 恭之, Deng Wu-Min 田守 洋一郎, 藤田 恭之, Deng Wu-Min 田守 洋一郎, 藤田 恭之, Deng Wu-Min 組織構築とがん化を制御する細胞競合の分子機構 マージャンによる細胞競合 組織構築とがん化を制御する細胞競合の分子機構 マージャンによる細胞競合 組織構築とがん化を制御する細胞競合の分子機構 マージャンによる細胞競合 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回, 4W18-5 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回, 4W18-5 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回, 4W18-5 2010/12 日本語 公開
Yoichiro Tamori, Carl Uli Bialucha, Ai-Guo Tian, Mihoko Kajita, Yi-Chun Huang, Mark Norman, Nicholas Harrison, John Poulton, Kenzo Ivanovitch, Lena Disch, Tao Liu, Wu-Min Deng, Yasuyuki Fujita Yoichiro Tamori, Carl Uli Bialucha, Ai-Guo Tian, Mihoko Kajita, Yi-Chun Huang, Mark Norman, Nicholas Harrison, John Poulton, Kenzo Ivanovitch, Lena Disch, Tao Liu, Wu-Min Deng, Yasuyuki Fujita Yoichiro Tamori, Carl Uli Bialucha, Ai-Guo Tian, Mihoko Kajita, Yi-Chun Huang, Mark Norman, Nicholas Harrison, John Poulton, Kenzo Ivanovitch, Lena Disch, Tao Liu, Wu-Min Deng, Yasuyuki Fujita Involvement of Lgl and Mahjong/VprBP in Cell Competition Involvement of Lgl and Mahjong/VprBP in Cell Competition Involvement of Lgl and Mahjong/VprBP in Cell Competition PLOS BIOLOGY, 8, 7, e1000422 PLOS BIOLOGY, 8, 7, e1000422 PLOS BIOLOGY, 8, 7, e1000422 2010/07 英語 公開
田守洋一郎, 藤田恭之, DENG Wu‐Min 田守洋一郎, 藤田恭之, DENG Wu‐Min 田守洋一郎, 藤田恭之, DENG Wu‐Min マージャンによる細胞競合 マージャンによる細胞競合 マージャンによる細胞競合 生化学, ROMBUNNO.4W18-5 生化学, ROMBUNNO.4W18-5 生化学, ROMBUNNO.4W18-5 2010 日本語 公開
梶田 美穂子, 藤田 恭之 梶田 美穂子, 藤田 恭之 KAJITA Mihoko, FUJITA Yasuyuki 正常上皮細胞と変異上皮細胞間の相互作用 正常上皮細胞と変異上皮細胞間の相互作用 Interaction between normal and transformed epithelial cells 生化學, 81, 4, 267-276 生化學, 81, 4, 267-276 , 81, 4, 267-276 2009/04/25 日本語 公開
Filipa Carreira-Barbosa, Mihoko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Filipa Carreira-Barbosa, Mihoko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Filipa Carreira-Barbosa, Mihoko Kajita, Veronique Morel, Hironori Wada, Hitoshi Okamoto, Alfonso Martinez Arias, Yasuyuki Fujita, Stephen W. Wilson, Masazumi Tada Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation (vol 136, pg 383, 2009) Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation (vol 136, pg 383, 2009) Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation (vol 136, pg 383, 2009) DEVELOPMENT, 136, 5, 877-877 DEVELOPMENT, 136, 5, 877-877 DEVELOPMENT, 136, 5, 877-877 2009/03 英語 その他記事 公開
N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud N Pinal, DCI Goberdhan, L Collinson, Y Fujita, IM Cox, C Wilson, F Pichaud Regulated and polarized Ptdins(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells (vol 16, pg 140, 2006) Regulated and polarized Ptdins(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells (vol 16, pg 140, 2006) Regulated and polarized Ptdins(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells (vol 16, pg 140, 2006) CURRENT BIOLOGY, 16, 3, 332-332 CURRENT BIOLOGY, 16, 3, 332-332 CURRENT BIOLOGY, 16, 3, 332-332 2006/02 英語 その他記事 公開
藤田恭之, 高井義美 藤田恭之, 高井義美 細胞内シグナル伝達 G蛋白質 Rab3Aと神経伝達物質の放出機構 細胞内シグナル伝達 G蛋白質 Rab3Aと神経伝達物質の放出機構 蛋白質 核酸 酵素, 42, 3, 364-370 蛋白質 核酸 酵素, 42, 3, 364-370 , 42, 3, 364-370 1997/02 日本語 公開
タイトル言語:
外部資金:競争的資金 (科学研究費補助金)
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(A) 代表 細胞競合と接触阻害を統合的に制御する分子メカニズムの解明 (2019年度分) 2019/04/01〜2020/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
細胞と分子の基礎生物学 Fundamentals of Cell and Molecular Biology 前期 全学共通科目 2020/04〜2021/03
部局運営(役職等)
役職名 期間
動物実験施設管理委員会 2020/04/01〜2022/03/31