杉本 直志

最終更新日時: 2018/07/05 14:35:41

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氏名(漢字/フリガナ/アルファベット表記)
杉本 直志/スギモト ナオシ/Sugimoto, Naoshi
所属部署・職名(部局/所属/講座等/職名)
iPS細胞研究所/臨床応用研究部門/特定拠点講師
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
ORCID ID
orcid.org/0000-0002-7271-9175
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Stem cells translational medicine, 6, 3, 720-730 Stem cells translational medicine, 6, 3, 720-730 Stem cells translational medicine, 6, 3, 720-730 2017/03 公開
Aihara A, Koike T, Abe N, Nakamura S, Sawaguchi A, Nakamura T, Sugimoto N, Nakauchi H, Nishino T, Eto K Aihara A, Koike T, Abe N, Nakamura S, Sawaguchi A, Nakamura T, Sugimoto N, Nakauchi H, Nishino T, Eto K Aihara A, Koike T, Abe N, Nakamura S, Sawaguchi A, Nakamura T, Sugimoto N, Nakauchi H, Nishino T, Eto K Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. Blood advances, 1, 7, 468-476 Blood advances, 1, 7, 468-476 Blood advances, 1, 7, 468-476 2017/02 公開
Sugimoto N, Eto K Sugimoto N, Eto K Sugimoto N, Eto K Development of iPS cell-derived blood products and production guidelines. Development of iPS cell-derived blood products and production guidelines. Development of iPS cell-derived blood products and production guidelines. [Rinsho ketsueki] The Japanese journal of clinical hematology, 58, 10, 2150-2159 [Rinsho ketsueki] The Japanese journal of clinical hematology, 58, 10, 2150-2159 [Rinsho ketsueki] The Japanese journal of clinical hematology, 58, 10, 2150-2159 2017 公開
Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. Stem cells translational medicine Stem cells translational medicine Stem cells translational medicine 2016/10 公開
Ishiyama K, Takeda J, Kondo T, Sugimoto N, Kawabata H, Kitano T, Takaori-Kondo A Ishiyama K, Takeda J, Kondo T, Sugimoto N, Kawabata H, Kitano T, Takaori-Kondo A Ishiyama K, Takeda J, Kondo T, Sugimoto N, Kawabata H, Kitano T, Takaori-Kondo A Feasibility of salvage cord blood transplantation following fludarabine, melphalan and low-dose TBI for graft rejection after hematopoietic stem cell transplantation. Feasibility of salvage cord blood transplantation following fludarabine, melphalan and low-dose TBI for graft rejection after hematopoietic stem cell transplantation. Feasibility of salvage cord blood transplantation following fludarabine, melphalan and low-dose TBI for graft rejection after hematopoietic stem cell transplantation. Bone marrow transplantation, 51, 7, 985-987 Bone marrow transplantation, 51, 7, 985-987 Bone marrow transplantation, 51, 7, 985-987 2016/07 公開
Sha W, Mitoma H, Hanabuchi S, Bao M, Weng L, Sugimoto N, Liu Y, Zhang Z, Zhong J, Sun B, Liu YJ Sha W, Mitoma H, Hanabuchi S, Bao M, Weng L, Sugimoto N, Liu Y, Zhang Z, Zhong J, Sun B, Liu YJ Sha W, Mitoma H, Hanabuchi S, Bao M, Weng L, Sugimoto N, Liu Y, Zhang Z, Zhong J, Sun B, Liu YJ Human NLRP3 inflammasome senses multiple types of bacterial RNAs. Human NLRP3 inflammasome senses multiple types of bacterial RNAs. Human NLRP3 inflammasome senses multiple types of bacterial RNAs. Proceedings of the National Academy of Sciences of the United States of America, 111, 45, 16059-16064 Proceedings of the National Academy of Sciences of the United States of America, 111, 45, 16059-16064 Proceedings of the National Academy of Sciences of the United States of America, 111, 45, 16059-16064 2014/11 公開
Voo KS, Bover L, Harline ML, Weng J, Sugimoto N, Liu YJ Voo KS, Bover L, Harline ML, Weng J, Sugimoto N, Liu YJ Voo KS, Bover L, Harline ML, Weng J, Sugimoto N, Liu YJ Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. Journal of immunology (Baltimore, Md. : 1950), 193, 2, 627-634 Journal of immunology (Baltimore, Md. : 1950), 193, 2, 627-634 Journal of immunology (Baltimore, Md. : 1950), 193, 2, 627-634 2014/07 公開
Sugimoto N, Mitoma H, Kim T, Hanabuchi S, Liu YJ Sugimoto N, Mitoma H, Kim T, Hanabuchi S, Liu YJ Sugimoto N, Mitoma H, Kim T, Hanabuchi S, Liu YJ Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system. Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system. Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system. Proceedings of the National Academy of Sciences of the United States of America, 111, 21, 7747-7752 Proceedings of the National Academy of Sciences of the United States of America, 111, 21, 7747-7752 Proceedings of the National Academy of Sciences of the United States of America, 111, 21, 7747-7752 2014/05 公開
Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome. The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome. The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome. Immunity, 39, 1, 123-135 Immunity, 39, 1, 123-135 Immunity, 39, 1, 123-135 2013/07 公開
Li HS, Greeley N, Sugimoto N, Liu YJ, Watowich SS Li HS, Greeley N, Sugimoto N, Liu YJ, Watowich SS Li HS, Greeley N, Sugimoto N, Liu YJ, Watowich SS miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. PloS one, 7, 12, e52341 PloS one, 7, 12, e52341 PloS one, 7, 12, e52341 2012 公開
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. The Journal of experimental medicine, 204, 12, 2803-2812 The Journal of experimental medicine, 204, 12, 2803-2812 The Journal of experimental medicine, 204, 12, 2803-2812 2007/11 公開
Kitawaki T, Kadowaki N, Sugimoto N, Kambe N, Hori T, Miyachi Y, Nakahata T, Uchiyama T Kitawaki T, Kadowaki N, Sugimoto N, Kambe N, Hori T, Miyachi Y, Nakahata T, Uchiyama T Kitawaki T, Kadowaki N, Sugimoto N, Kambe N, Hori T, Miyachi Y, Nakahata T, Uchiyama T IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells. IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells. IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells. International immunology, 18, 12, 1789-1799 International immunology, 18, 12, 1789-1799 International immunology, 18, 12, 1789-1799 2006/12 公開
Sugimoto N, Oida T, Hirota K, Nakamura K, Nomura T, Uchiyama T, Sakaguchi S Sugimoto N, Oida T, Hirota K, Nakamura K, Nomura T, Uchiyama T, Sakaguchi S Sugimoto N, Oida T, Hirota K, Nakamura K, Nomura T, Uchiyama T, Sakaguchi S Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. International immunology, 18, 8, 1197-1209 International immunology, 18, 8, 1197-1209 International immunology, 18, 8, 1197-1209 2006/08 公開
Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sugimoto N, Okada N, Maruyama K, Uchiyama T Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sugimoto N, Okada N, Maruyama K, Uchiyama T Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sugimoto N, Okada N, Maruyama K, Uchiyama T Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity. Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity. Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity. Journal of immunotherapy (Hagerstown, Md. : 1997), 29, 2, 165-174 Journal of immunotherapy (Hagerstown, Md. : 1997), 29, 2, 165-174 Journal of immunotherapy (Hagerstown, Md. : 1997), 29, 2, 165-174 2006/03 公開
Watanabe N, Takahashi T, Sugimoto N, Tanaka Y, Kurata M, Matsushita A, Maeda A, Nagai K, Nasu K Watanabe N, Takahashi T, Sugimoto N, Tanaka Y, Kurata M, Matsushita A, Maeda A, Nagai K, Nasu K Watanabe N, Takahashi T, Sugimoto N, Tanaka Y, Kurata M, Matsushita A, Maeda A, Nagai K, Nasu K Excellent response of chemotherapy-resistant B-cell-type chronic lymphocytic leukemia with meningeal involvement to rituximab. Excellent response of chemotherapy-resistant B-cell-type chronic lymphocytic leukemia with meningeal involvement to rituximab. Excellent response of chemotherapy-resistant B-cell-type chronic lymphocytic leukemia with meningeal involvement to rituximab. International journal of clinical oncology, 10, 5, 357-361 International journal of clinical oncology, 10, 5, 357-361 International journal of clinical oncology, 10, 5, 357-361 2005/10 公開
Sugimoto N, Ishikawa T, Gotoh S, Shinzato I, Matsushita A, Nagai K, Ohgoh N, Takahashi T Sugimoto N, Ishikawa T, Gotoh S, Shinzato I, Matsushita A, Nagai K, Ohgoh N, Takahashi T Sugimoto N, Ishikawa T, Gotoh S, Shinzato I, Matsushita A, Nagai K, Ohgoh N, Takahashi T Primary myelofibrosis terminated in basophilic leukemia and successful allogeneic bone marrow transplantation. Primary myelofibrosis terminated in basophilic leukemia and successful allogeneic bone marrow transplantation. Primary myelofibrosis terminated in basophilic leukemia and successful allogeneic bone marrow transplantation. International journal of hematology, 80, 2, 183-185 International journal of hematology, 80, 2, 183-185 International journal of hematology, 80, 2, 183-185 2004/08 公開
Yanai M, Maeda A, Watanabe N, Sugimoto N, Matsushita A, Nagai K, Oida T, Takahashi T Yanai M, Maeda A, Watanabe N, Sugimoto N, Matsushita A, Nagai K, Oida T, Takahashi T Yanai M, Maeda A, Watanabe N, Sugimoto N, Matsushita A, Nagai K, Oida T, Takahashi T Successful treatment of mu-heavy chain disease with fludarabine monophosphate: a case report. Successful treatment of mu-heavy chain disease with fludarabine monophosphate: a case report. Successful treatment of mu-heavy chain disease with fludarabine monophosphate: a case report. International journal of hematology, 79, 2, 174-177 International journal of hematology, 79, 2, 174-177 International journal of hematology, 79, 2, 174-177 2004/02 公開
Watanabe N, Sugimoto N, Matsushita A, Maeda A, Nagai K, Hanioka K, Takahashi T Watanabe N, Sugimoto N, Matsushita A, Maeda A, Nagai K, Hanioka K, Takahashi T Watanabe N, Sugimoto N, Matsushita A, Maeda A, Nagai K, Hanioka K, Takahashi T Association of intestinal malignant lymphoma and ulcerative colitis. Association of intestinal malignant lymphoma and ulcerative colitis. Association of intestinal malignant lymphoma and ulcerative colitis. Internal medicine (Tokyo, Japan), 42, 12, 1183-1187 Internal medicine (Tokyo, Japan), 42, 12, 1183-1187 Internal medicine (Tokyo, Japan), 42, 12, 1183-1187 2003/12 公開
Mochizuki T, Karavanov AA, Curtiss PE, Ault KT, Sugimoto N, Watabe T, Shiokawa K, Jamrich M, Cho KW, Dawid IB, Taira M Mochizuki T, Karavanov AA, Curtiss PE, Ault KT, Sugimoto N, Watabe T, Shiokawa K, Jamrich M, Cho KW, Dawid IB, Taira M Mochizuki T, Karavanov AA, Curtiss PE, Ault KT, Sugimoto N, Watabe T, Shiokawa K, Jamrich M, Cho KW, Dawid IB, Taira M Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter. Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter. Xlim-1 and LIM domain binding protein 1 cooperate with various transcription factors in the regulation of the goosecoid promoter. Developmental biology, 224, 2, 470-485 Developmental biology, 224, 2, 470-485 Developmental biology, 224, 2, 470-485 2000/08 公開

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Misc
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Sugimoto N, Eto K Sugimoto N, Eto K Sugimoto N, Eto K Platelet production from induced pluripotent stem cells Platelet production from induced pluripotent stem cells Platelet production from induced pluripotent stem cells J Thromb Haemost, 15, 9, 1717-1727 J Thromb Haemost, 15, 9, 1717-1727 J Thromb Haemost, 15, 9, 1717-1727 2017/09 英語 総説・解説(学術雑誌) 公開
杉本直志、江藤浩之 杉本直志、江藤浩之 iPS細胞を用いた新たな輸血医療 iPS細胞を用いた新たな輸血医療 日本内科学会雑誌, 106, 4, 843-849 日本内科学会雑誌, 106, 4, 843-849 , 106, 4, 843-849 2017 日本語 総説・解説(学術雑誌) 公開
杉本直志、江藤浩之 杉本直志、江藤浩之 iPS細胞を用いた血液製剤の開発と法整備 iPS細胞を用いた血液製剤の開発と法整備 臨床血液, 58, 10, 2150-2159 臨床血液, 58, 10, 2150-2159 , 58, 10, 2150-2159 日本語 総説・解説(学術雑誌) 公開
タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
iPS細胞からの血小板の作製[招待あり] iPS細胞からの血小板の作製 [招待あり] 第66回日本輸血・細胞治療学会総会 第66回日本輸血・細胞治療学会総会 2018/05/25 日本語 シンポジウム・ワークショップパネル(指名) 公開
HLA gene knockout in human iPS cells: a tool in developing versatile cellular regenerative therapy[招待あり] HLA gene knockout in human iPS cells: a tool in developing versatile cellular regenerative therapy [招待あり] HLA gene knockout in human iPS cells: a tool in developing versatile cellular regenerative therapy [招待あり] 第26回日本組織適合性学会大会 第26回日本組織適合性学会大会 2017/10/28 英語 公開講演、セミナー、チュートリアル、講習、講義 公開
iPS細胞を用いた血液製剤の開発と法整備[招待あり] iPS細胞を用いた血液製剤の開発と法整備 [招待あり] 第79回日本血液学会学術集会 第79回日本血液学会学術集会 2017/10/21 日本語 公開講演、セミナー、チュートリアル、講習、講義 公開
京都大学医学部附属病院における高齢者の同種造血幹細胞移植の成績 京都大学医学部附属病院における高齢者の同種造血幹細胞移植の成績 第77回日本血液学会学術集会 第77回日本血液学会学術集会 2015/10 日本語 口頭発表(一般) 公開
Helicase Proteins DHX29 and RIG-I Cosense Cytosolic Nucleic Acids in the Human Airway System Helicase Proteins DHX29 and RIG-I Cosense Cytosolic Nucleic Acids in the Human Airway System Helicase Proteins DHX29 and RIG-I Cosense Cytosolic Nucleic Acids in the Human Airway System 口演(Best Presentation Award)、第43回日本免疫学会学術集会(2014), Kyoto 口演(Best Presentation Award)、第43回日本免疫学会学術集会(2014), Kyoto 2014/12 英語 口頭発表(一般) 公開
ヘリカーゼ・タンパクDHX29とRIG-Iによるヒト気道組織のウィルス/核酸の細胞質内センシングとサイトカイン産生[招待あり] ヘリカーゼ・タンパクDHX29とRIG-Iによるヒト気道組織のウィルス/核酸の細胞質内センシングとサイトカイン産生 [招待あり] 招待講演、第10回感染症サイトカイン研究会 (2014)、 神戸 招待講演、第10回感染症サイトカイン研究会 (2014)、 神戸 2014 日本語 公開講演、セミナー、チュートリアル、講習、講義 公開
DUSP4 Stabilizes FOXP3 Expression In Human Regulatory T Cells DUSP4 Stabilizes FOXP3 Expression In Human Regulatory T Cells DUSP4 Stabilizes FOXP3 Expression In Human Regulatory T Cells 55th Annual Meeting of the American Society of Hematology (2013), New Orleans 55th Annual Meeting of the American Society of Hematology (2013), New Orleans 55th Annual Meeting of the American Society of Hematology (2013), New Orleans 2013/12 英語 ポスター発表 公開
TGFβによるナイーブCD4+T細胞のFoxp3遺伝子発現誘導の定量的解析 TGFβによるナイーブCD4+T細胞のFoxp3遺伝子発現誘導の定量的解析 第34回日本免疫学会総会 (2004) 第34回日本免疫学会総会 (2004) 2004 口頭発表(一般) 公開
好塩基球性白血病にいたり同種骨髄移植に成功した原発性骨髄線維症の一例 好塩基球性白血病にいたり同種骨髄移植に成功した原発性骨髄線維症の一例 第60回日本免疫学会学術集会 第60回日本免疫学会学術集会 2000 日本語 ポスター発表 公開
細胞質核酸センサーによる感染防御とその臨床的意義 細胞質核酸センサーによる感染防御とその臨床的意義 招待講演、第3回京都血液フォーラム (2015) 招待講演、第3回京都血液フォーラム (2015) 日本語 公開講演、セミナー、チュートリアル、講習、講義 公開
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis 第36回日本免疫学会学術集会 (2006), Osaka 第36回日本免疫学会学術集会 (2006), Osaka 英語 口頭発表(一般) 公開

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書籍等出版物
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 出版社 出版社(日本語) 出版社(英語) 出版年月 記述言語 担当区分 公開
杉本 直志 杉本 直志 ハリソン内科学 ハリソン内科学 2017 共訳 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(C) 代表 血液細胞の免疫反応および造血器腫瘍における核酸センサー分子DHX29の役割 (平成29年度分) 2017/04/01〜2018/03/31