岡本 郁弘

最終更新日時: 2019/06/05 17:15:21

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氏名(漢字/フリガナ/アルファベット表記)
岡本 郁弘/オカモト イクヒロ/Okamoto, Ikuhiro
所属部署・職名(部局/所属/講座等/職名)
高等研究院/ヒト生物学高等研究拠点/特定講師
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
修士(地球環境科学) 北海道大学
博士(地球環境科学) 北海道大学
ORCID ID
https://orcid.org/https://orcid.org/0000-0002-2870-8321
researchmap URL
https://researchmap.jp/7000009233
研究テーマ
(日本語)
哺乳類の雌におけるX染色体の不活性化
(英語)
X chromosome inactivation in mammals
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
X 染色体 X chromosome
エピジェネティクス epigenetics
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG A symmetric toggle switch explains the onset of random X inactivation in different mammals. A symmetric toggle switch explains the onset of random X inactivation in different mammals. A symmetric toggle switch explains the onset of random X inactivation in different mammals. Nature structural & molecular biology, 26, 5, 350-360 Nature structural & molecular biology, 26, 5, 350-360 Nature structural & molecular biology, 26, 5, 350-360 2019/05 公開
Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T, Saitou M Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Science (New York, N.Y.), 362, 6412, 356-360 Science (New York, N.Y.), 362, 6412, 356-360 Science (New York, N.Y.), 362, 6412, 356-360 2018/10 公開
Okamoto I Okamoto I Okamoto I Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Combined Immunofluorescence, RNA FISH, and DNA FISH in Preimplantation Mouse Embryos. Methods in molecular biology (Clifton, N.J.), 1861, 149-159 Methods in molecular biology (Clifton, N.J.), 1861, 149-159 Methods in molecular biology (Clifton, N.J.), 1861, 149-159 2018 公開
Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass. Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass. Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass. Nature communications, 8, 1, 1297 Nature communications, 8, 1, 1297 Nature communications, 8, 1, 1297 2017/11 公開
Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, Hagiwara M, Shirane K, Sasaki H, Saitou M <i>In vitro</i> expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. <i>In vitro</i> expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. <i>In vitro</i> expansion of mouse primordial germ cell-like cells recapitulates an epigenetic blank slate. The EMBO journal, 36, 13, 1888-1907 The EMBO journal, 36, 13, 1888-1907 The EMBO journal, 36, 13, 1888-1907 2017/07 公開
Nakamura T, Yabuta Y, Okamoto I, Sasaki K, Iwatani C, Tsuchiya H, Saitou M Nakamura T, Yabuta Y, Okamoto I, Sasaki K, Iwatani C, Tsuchiya H, Saitou M Nakamura T, Yabuta Y, Okamoto I, Sasaki K, Iwatani C, Tsuchiya H, Saitou M Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys. Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys. Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys. Scientific data, 4, 170067 Scientific data, 4, 170067 Scientific data, 4, 170067 2017 公開
Ranisavljevic N, Okamoto I, Heard E, Ancelin K Ranisavljevic N, Okamoto I, Heard E, Ancelin K Ranisavljevic N, Okamoto I, Heard E, Ancelin K RNA FISH to Study Zygotic Genome Activation in Early Mouse Embryos. RNA FISH to Study Zygotic Genome Activation in Early Mouse Embryos. RNA FISH to Study Zygotic Genome Activation in Early Mouse Embryos. Methods in molecular biology (Clifton, N.J.), 1605, 133-145 Methods in molecular biology (Clifton, N.J.), 1605, 133-145 Methods in molecular biology (Clifton, N.J.), 1605, 133-145 2017 公開
Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M Ishikura Y, Yabuta Y, Ohta H, Hayashi K, Nakamura T, Okamoto I, Yamamoto T, Kurimoto K, Shirane K, Sasaki H, Saitou M In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells. Cell reports, 17, 10, 2789-2804 Cell reports, 17, 10, 2789-2804 Cell reports, 17, 10, 2789-2804 2016/12 公開
Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. Developmental cell, 39, 2, 169-185 Developmental cell, 39, 2, 169-185 Developmental cell, 39, 2, 169-185 2016/10 公開
Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M A developmental coordinate of pluripotency among mice, monkeys and humans. A developmental coordinate of pluripotency among mice, monkeys and humans. A developmental coordinate of pluripotency among mice, monkeys and humans. Nature, 537, 7618, 57-62 Nature, 537, 7618, 57-62 Nature, 537, 7618, 57-62 2016/09 公開
Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 2015/08 公開
Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M Nakamura T, Yabuta Y, Okamoto I, Aramaki S, Yokobayashi S, Kurimoto K, Sekiguchi K, Nakagawa M, Yamamoto T, Saitou M SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression. Nucleic acids research, 43, 9, e60 Nucleic acids research, 43, 9, e60 Nucleic acids research, 43, 9, e60 2015/05 公開
R. Duffié; S. Ajjan; M.V. Greenberg; N. Zamudio; M. del Arenal Escamilla; J. Iranzo; I. Okamoto; S. Barbaux; P. Fauque; D. Bourc'his R. Duffié; S. Ajjan; M.V. Greenberg; N. Zamudio; M. del Arenal Escamilla; J. Iranzo; I. Okamoto; S. Barbaux; P. Fauque; D. Bourc'his R. Duffié; S. Ajjan; M.V. Greenberg; N. Zamudio; M. del Arenal Escamilla; J. Iranzo; I. Okamoto; S. Barbaux; P. Fauque; D. Bourc'his The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals Genes and Development, 28, 5, 463-478 Genes and Development, 28, 5, 463-478 Genes and Development, 28, 5, 463-478 2014/03 英語 公開
E.G. Schulz; J. Meisig; T. Nakamura; I. Okamoto; A. Sieber; C. Picard; M. Borensztein; M. Saitou; N. Blüthgen; E. Heard E.G. Schulz; J. Meisig; T. Nakamura; I. Okamoto; A. Sieber; C. Picard; M. Borensztein; M. Saitou; N. Blüthgen; E. Heard E.G. Schulz; J. Meisig; T. Nakamura; I. Okamoto; A. Sieber; C. Picard; M. Borensztein; M. Saitou; N. Blüthgen; E. Heard The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network Cell Stem Cell, 14, 2, 203-216 Cell Stem Cell, 14, 2, 203-216 Cell Stem Cell, 14, 2, 203-216 2014 英語 公開
Patrat C, Okamoto I, Heard E Patrat C, Okamoto I, Heard E Patrat C, Okamoto I, Heard E [Initiation of X chromosome inactivation during early embryogenesis in mice and in humans]. [Initiation of X chromosome inactivation during early embryogenesis in mice and in humans]. [Initiation of X chromosome inactivation during early embryogenesis in mice and in humans]. Bulletin de l'Academie nationale de medecine, 197, 3, 609-617 Bulletin de l'Academie nationale de medecine, 197, 3, 609-617 Bulletin de l'Academie nationale de medecine, 197, 3, 609-617 2013/03 公開
C. Ciaudo; F. Jay; I. Okamoto; C.-J. Chen; A. Sarazin; N. Servant; E. Barillot; E. Heard; O. Voinnet C. Ciaudo; F. Jay; I. Okamoto; C.-J. Chen; A. Sarazin; N. Servant; E. Barillot; E. Heard; O. Voinnet C. Ciaudo; F. Jay; I. Okamoto; C.-J. Chen; A. Sarazin; N. Servant; E. Barillot; E. Heard; O. Voinnet RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells PLoS Genetics, 9, 11 PLoS Genetics, 9, 11 PLoS Genetics, 9, 11 2013 英語 公開
E.P. Nora; B.R. Lajoie; E.G. Schulz; L. Giorgetti; I. Okamoto; N. Servant; T. Piolot; N.L. Van Berkum; J. Meisig; J. Sedat; J. Gribnau; E. Barillot; N. Blüthgen; J. Dekker; E. Heard E.P. Nora; B.R. Lajoie; E.G. Schulz; L. Giorgetti; I. Okamoto; N. Servant; T. Piolot; N.L. Van Berkum; J. Meisig; J. Sedat; J. Gribnau; E. Barillot; N. Blüthgen; J. Dekker; E. Heard E.P. Nora; B.R. Lajoie; E.G. Schulz; L. Giorgetti; I. Okamoto; N. Servant; T. Piolot; N.L. Van Berkum; J. Meisig; J. Sedat; J. Gribnau; E. Barillot; N. Blüthgen; J. Dekker; E. Heard Spatial partitioning of the regulatory landscape of the X-inactivation centre Spatial partitioning of the regulatory landscape of the X-inactivation centre Spatial partitioning of the regulatory landscape of the X-inactivation centre Nature, 485, 7398, 381-385 Nature, 485, 7398, 381-385 Nature, 485, 7398, 381-385 2012 英語 公開
I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development Nature, 472, 7343, 370-374 Nature, 472, 7343, 370-374 Nature, 472, 7343, 370-374 2011 英語 公開
I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard I. Okamoto; C. Patrat; D. Thépot; N. Peynot; P. Fauque; N. Daniel; P. Diabangouaya; J.-P. Wolf; J.-P. Renard; V. Duranthon; E. Heard Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (Nature (2011) 472 (370-374)) Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (Nature (2011) 472 (370-374)) Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development (Nature (2011) 472 (370-374)) Nature, 474, 7350, 239-240 Nature, 474, 7350, 239-240 Nature, 474, 7350, 239-240 2011 英語 公開
A. Probst; I. Okamoto; M. Casanova; F. El Marjou; P. Le Baccon; G. Almouzni A. Probst; I. Okamoto; M. Casanova; F. El Marjou; P. Le Baccon; G. Almouzni A. Probst; I. Okamoto; M. Casanova; F. El Marjou; P. Le Baccon; G. Almouzni A Strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development A Strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development A Strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development Developmental Cell, 19, 4, 625-638 Developmental Cell, 19, 4, 625-638 Developmental Cell, 19, 4, 625-638 2010 英語 公開
H. Oda; I. Okamoto; N. Murphy; J. Chu; S.M. Price; M.M. Shen; M.E. Torres-Padilla; E. Heard; D. Reinberg H. Oda; I. Okamoto; N. Murphy; J. Chu; S.M. Price; M.M. Shen; M.E. Torres-Padilla; E. Heard; D. Reinberg H. Oda; I. Okamoto; N. Murphy; J. Chu; S.M. Price; M.M. Shen; M.E. Torres-Padilla; E. Heard; D. Reinberg Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development Molecular and Cellular Biology, 29, 8, 2278-2295 Molecular and Cellular Biology, 29, 8, 2278-2295 Molecular and Cellular Biology, 29, 8, 2278-2295 2009 英語 公開
I. Okamoto; E. Heard I. Okamoto; E. Heard I. Okamoto; E. Heard Lessons from comparative analysis of X-chromosome inactivation in mammals Lessons from comparative analysis of X-chromosome inactivation in mammals Lessons from comparative analysis of X-chromosome inactivation in mammals Chromosome Research, 17, 5, 659-669 Chromosome Research, 17, 5, 659-669 Chromosome Research, 17, 5, 659-669 2009 英語 公開
I. Okamoto; E. Heard I. Okamoto; E. Heard I. Okamoto; E. Heard The dynamics of imprinted X inactivation during preimplantation development in mice The dynamics of imprinted X inactivation during preimplantation development in mice The dynamics of imprinted X inactivation during preimplantation development in mice Cytogenetic and Genome Research, 113, 1-4, 318-324 Cytogenetic and Genome Research, 113, 1-4, 318-324 Cytogenetic and Genome Research, 113, 1-4, 318-324 2006 英語 公開
T. Kunath; D. Arnaud; G.D. Uy; I. Okamoto; C. Chureau; Y. Yamanaka; E. Heard; R.L. Gardner; P. Avner; J. Rossant T. Kunath; D. Arnaud; G.D. Uy; I. Okamoto; C. Chureau; Y. Yamanaka; E. Heard; R.L. Gardner; P. Avner; J. Rossant T. Kunath; D. Arnaud; G.D. Uy; I. Okamoto; C. Chureau; Y. Yamanaka; E. Heard; R.L. Gardner; P. Avner; J. Rossant Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Development, 132, 7, 1649-1661 Development, 132, 7, 1649-1661 Development, 132, 7, 1649-1661 2005 英語 公開
S. Bao; N. Miyoshi; I. Okamoto; T. Jenuwein; E. Heard; M. Azim Surani S. Bao; N. Miyoshi; I. Okamoto; T. Jenuwein; E. Heard; M. Azim Surani S. Bao; N. Miyoshi; I. Okamoto; T. Jenuwein; E. Heard; M. Azim Surani Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte EMBO Reports, 6, 8, 748-754 EMBO Reports, 6, 8, 748-754 EMBO Reports, 6, 8, 748-754 2005 英語 公開
I. Okamoto; D. Arnaud; P. Le Baccon; A.P. Otte; C.M. Disteche; P. Avner; E. Heard I. Okamoto; D. Arnaud; P. Le Baccon; A.P. Otte; C.M. Disteche; P. Avner; E. Heard I. Okamoto; D. Arnaud; P. Le Baccon; A.P. Otte; C.M. Disteche; P. Avner; E. Heard Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice Nature, 438, 7066, 369-373 Nature, 438, 7066, 369-373 Nature, 438, 7066, 369-373 2005 英語 公開
I. Okamoto; A.P. Otte; C.D. Allis; D. Reinberg; E. Heard I. Okamoto; A.P. Otte; C.D. Allis; D. Reinberg; E. Heard I. Okamoto; A.P. Otte; C.D. Allis; D. Reinberg; E. Heard Epigenetic Dynamics of Imprinted X Inactivation during Early Mouse Development Epigenetic Dynamics of Imprinted X Inactivation during Early Mouse Development Epigenetic Dynamics of Imprinted X Inactivation during Early Mouse Development Science, 303, 5658, 644-649 Science, 303, 5658, 644-649 Science, 303, 5658, 644-649 2004 英語 公開
J. Chaumeil; I. Okamoto; E. Heard J. Chaumeil; I. Okamoto; E. Heard J. Chaumeil; I. Okamoto; E. Heard X-Chromosome Inactivation in Mouse Embryonic Stem Cells: Analysis of Histone Modifications and Transcriptional Activity Using Immunofluorescence and FISH X-Chromosome Inactivation in Mouse Embryonic Stem Cells: Analysis of Histone Modifications and Transcriptional Activity Using Immunofluorescence and FISH X-Chromosome Inactivation in Mouse Embryonic Stem Cells: Analysis of Histone Modifications and Transcriptional Activity Using Immunofluorescence and FISH Methods in Enzymology, 376, 405-419 Methods in Enzymology, 376, 405-419 Methods in Enzymology, 376, 405-419 2004 英語 公開
E. Heard; J. Chaumeil; O. Masui; I. Okamoto E. Heard; J. Chaumeil; O. Masui; I. Okamoto E. Heard; J. Chaumeil; O. Masui; I. Okamoto Mammalian X-chromosome inactivation: An epigenetics paradigm Mammalian X-chromosome inactivation: An epigenetics paradigm Mammalian X-chromosome inactivation: An epigenetics paradigm Cold Spring Harbor Symposia on Quantitative Biology, 69, 89-102 Cold Spring Harbor Symposia on Quantitative Biology, 69, 89-102 Cold Spring Harbor Symposia on Quantitative Biology, 69, 89-102 2004 英語 公開
H. Mizuno; I. Okamoto; N. Takagi H. Mizuno; I. Okamoto; N. Takagi H. Mizuno; I. Okamoto; N. Takagi Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome Developmental abnormalities in mouse embryos tetrasomic for chromosome 11: Apparent similarity to embryos functionally disomic for the X chromosome Genes and Genetic Systems, 77, 4, 269-276 Genes and Genetic Systems, 77, 4, 269-276 Genes and Genetic Systems, 77, 4, 269-276 2002 英語 公開
J. Chaumeil; I. Okamoto; M. Guggiari; E. Heard J. Chaumeil; I. Okamoto; M. Guggiari; E. Heard J. Chaumeil; I. Okamoto; M. Guggiari; E. Heard Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells Cytogenetic and Genome Research, 99, 1-4, 75-84 Cytogenetic and Genome Research, 99, 1-4, 75-84 Cytogenetic and Genome Research, 99, 1-4, 75-84 2002 英語 公開
I. Okamoto; S.-S. Tan; N. Takagi I. Okamoto; S.-S. Tan; N. Takagi I. Okamoto; S.-S. Tan; N. Takagi X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation Development, 127, 19, 4137-4145 Development, 127, 19, 4137-4145 Development, 127, 19, 4137-4145 2000 英語 公開

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タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 2013〜2016
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(B) 代表 始原生殖細胞における不活性X染色体再活性化メカニズムの解明 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 霊長類におけるX染色体不活性化機構の解明 (平成30年度分) 2018/04/01〜2019/03/31
学外非常勤講師
講義名(日本語) 講義名(英語) 開講期 学校名 学部/研究科名 期間
分子生物学特論 前期 北海道大学 大学院生命科学院 2013/06/21〜2013/06/21
大学院特別セミナー 医学特論 後期 富山大学 医学薬学教育部 2018/10/01〜2018/10/01