武田 俊一

最終更新日時: 2019/06/14 14:46:21

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氏名(漢字/フリガナ/アルファベット表記)
武田 俊一/タケダ シユンイチ/Takeda, Shunichi
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学専攻遺伝医学講座放射線遺伝学/教授
学部兼担
部局 所属 講座等 職名
医学部
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8501 京都府京都市左京区吉田近衛町 Yoshidakonoecho, Sakyo-ku, Kyoto-city, Kyoto 606-8501 Japan
連絡先電話番号
種別 番号
職場 075-753-4410/4411
電子メールアドレス
メールアドレス
stakeda @ rg.med.kyoto-u.ac.jp
所属学会(国内)
学会名(日本語) 学会名(英語)
癌学会 The Japan Society of Cancer Biology
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
医学博士 M.D. 大阪大学 Osaka University
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
大阪大学 Osaka University 大学院医学研究科博士課程(生理系) Graduate School of Medicine 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
大阪大学 Osaka University 医学部医学科 School of Medicine 卒業
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
1985/04/〜1986/04/ 京都大学大学院医学研究科医化学I Graduate School of Medicine, Kyoto University 特別研究員 PD
1986/05/〜1988/04/ 京都大学大学院医学研究科医化学I Graduate School of Medicine, Kyoto University 助手 Assistant
1988/05/〜1995/3 スイス・バーゼル免疫研究所 Basel Institute for Immunology, Switzerland 研究員 Research Fellow
1995/04/〜1998/11/ 京都大学大学院医学研究科寄附講座 Graduate School of Medicine, Kyoto University 客員教授 Affiliate professor
1998/12/〜 京都大学大学院医学研究科放射線遺伝学 Department of Radiation Genetics, Graduate School of Medicine, Kyoto University 教授 Professor
使用言語
言語名
英語
個人ホームページ
URL
http://rg4.rg.med.kyoto-u.ac.jp/
researchmap URL
https://researchmap.jp/read0080503
研究テーマ
(日本語)
逆遺伝学的手法を用いた発がんとがん治療の分子メカニズムの研究、遺伝子破壊細胞間のプロテオソームの比較、遺伝子破壊DT40細胞を使った抗がん治療薬シーズの検索
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
DNA修復、DNA組み換え、遺伝子治療、癌の化学療法、放射線生物学 DNA repair, DNA recombination, Gene therapy, Chemotherapy of cancer, Radiation Biology
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes. BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes. Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America Proceedings of the National Academy of Sciences of the United States of America 2018/10 公開
Hu X, Wu X, Liu H, Cheng Z, Zhao Z, Xiang C, Feng X, Takeda S, Qing Y Hu X, Wu X, Liu H, Cheng Z, Zhao Z, Xiang C, Feng X, Takeda S, Qing Y Hu X, Wu X, Liu H, Cheng Z, Zhao Z, Xiang C, Feng X, Takeda S, Qing Y Genistein-induced DNA damage is repaired by nonhomologous end joining and homologous recombination in TK6 cells. Genistein-induced DNA damage is repaired by nonhomologous end joining and homologous recombination in TK6 cells. Genistein-induced DNA damage is repaired by nonhomologous end joining and homologous recombination in TK6 cells. Journal of cellular physiology Journal of cellular physiology Journal of cellular physiology 2018/08 公開
Nakazato A, Kajita K, Ooka M, Akagawa R, Abe T, Takeda S, Branzei D, Hirota K Nakazato A, Kajita K, Ooka M, Akagawa R, Abe T, Takeda S, Branzei D, Hirota K Nakazato A, Kajita K, Ooka M, Akagawa R, Abe T, Takeda S, Branzei D, Hirota K SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells. SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells. SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells. DNA repair, 68, 50-57 DNA repair, 68, 50-57 DNA repair, 68, 50-57 2018/08 公開
Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms. Environmental and molecular mutagenesis, 59, 6, 529-538 Environmental and molecular mutagenesis, 59, 6, 529-538 Environmental and molecular mutagenesis, 59, 6, 529-538 2018/07 公開
Paddock MN, Buelow BD, Takeda S, Scharenberg AM Paddock MN, Buelow BD, Takeda S, Scharenberg AM Paddock MN, Buelow BD, Takeda S, Scharenberg AM Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion. Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion. Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion. PLoS biology, 16, 3, e1002621 PLoS biology, 16, 3, e1002621 PLoS biology, 16, 3, e1002621 2018/03 公開
Rakers C, Najnin RA, Polash AH, Takeda S, Brown JB Rakers C, Najnin RA, Polash AH, Takeda S, Brown JB Rakers C, Najnin RA, Polash AH, Takeda S, Brown JB Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices: A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families. Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices: A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families. Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices: A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families. ChemMedChem, 13, 6, 511-521 ChemMedChem, 13, 6, 511-521 ChemMedChem, 13, 6, 511-521 2018/03 公開
Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga SI Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga SI Sanada Y, Sasanuma H, Takeda S, Tano K, Masunaga SI Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma. Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma. Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma. International journal of radiation biology, 94, 1, 88-96 International journal of radiation biology, 94, 1, 88-96 International journal of radiation biology, 94, 1, 88-96 2018/01 公開
Ooka M, Abe T, Cho K, Koike K, Takeda S, Hirota K Ooka M, Abe T, Cho K, Koike K, Takeda S, Hirota K Ooka M, Abe T, Cho K, Koike K, Takeda S, Hirota K Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression. Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression. Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression. PloS one, 13, 2, e0192421 PloS one, 13, 2, e0192421 PloS one, 13, 2, e0192421 2018 公開
Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH Çaglayan M, Prasad R, Krasich R, Longley MJ, Kadoda K, Tsuda M, Sasanuma H, Takeda S, Tano K, Copeland WC, Wilson SH Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts. Nucleic acids research, 45, 17, 10079-10088 Nucleic acids research, 45, 17, 10079-10088 Nucleic acids research, 45, 17, 10079-10088 2017/09 公開
Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair. PloS one, 12, 11, e0188320 PloS one, 12, 11, e0188320 PloS one, 12, 11, e0188320 2017 公開
S.-I. Chisada; T. Kurokawa; K. Murashita; I. Rønnestad; Y. Taniguchi; A. Toyoda; Y. Sakaki; S. Takeda; Y. Yoshiura S.-I. Chisada; T. Kurokawa; K. Murashita; I. Rønnestad; Y. Taniguchi; A. Toyoda; Y. Sakaki; S. Takeda; Y. Yoshiura Leptin receptor-deficient (knockout) medaka, Oryzias latipes, show chronical up-regulated levels of orexigenic neuropeptides, elevated food intake and stage specific effects on growth and fat allocation Leptin receptor-deficient (knockout) medaka, Oryzias latipes, show chronical up-regulated levels of orexigenic neuropeptides, elevated food intake and stage specific effects on growth and fat allocation General and Comparative Endocrinology, 195, 9-20 , 195, 9-20 General and Comparative Endocrinology, 195, 9-20 2014 英語 公開
Mohiuddin; I.S. Keka; T.J. Evans; K. Hirota; H. Shimizu; K. Kono; S. Takeda; S. Hirano Mohiuddin; I.S. Keka; T.J. Evans; K. Hirota; H. Shimizu; K. Kono; S. Takeda; S. Hirano A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes Archives of Toxicology, 88, 1, 145-160 , 88, 1, 145-160 Archives of Toxicology, 88, 1, 145-160 2014 英語 公開
M. Al Abo; D. Dejsuphong; K. Hirota; Y. Yonetani; M. Yamazoe; H. Kurumizaka; S. Takeda M. Al Abo; D. Dejsuphong; K. Hirota; Y. Yonetani; M. Yamazoe; H. Kurumizaka; S. Takeda Compensatory functions and interdependency of the DNABinding domain of BRCA2 with the BRCA1-PALB2-BRCA2 complex Compensatory functions and interdependency of the DNABinding domain of BRCA2 with the BRCA1-PALB2-BRCA2 complex Cancer Research, 74, 3, 797-807 , 74, 3, 797-807 Cancer Research, 74, 3, 797-807 2014 英語 公開
J. Murai; S.-Y.N. Huang; A. Renaud; Y. Zhang; J. Ji; S. Takeda; J. Morris; B. Teicher; J.H. Doroshow; Y. Pommier J. Murai; S.-Y.N. Huang; A. Renaud; Y. Zhang; J. Ji; S. Takeda; J. Morris; B. Teicher; J.H. Doroshow; Y. Pommier Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib Molecular Cancer Therapeutics, 13, 2, 433-443 , 13, 2, 433-443 Molecular Cancer Therapeutics, 13, 2, 433-443 2014 英語 公開
Y. Hosono; T. Abe; M. Ishiai; M.N. Islam; H. Arakawa; W. Wang; S. Takeda; Y. Ishii; M. Takata; M. Seki; T. Enomoto Y. Hosono; T. Abe; M. Ishiai; M.N. Islam; H. Arakawa; W. Wang; S. Takeda; Y. Ishii; M. Takata; M. Seki; T. Enomoto Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents Biochimica et Biophysica Acta - Molecular Cell Research, 1843, 5, 1002-1012 , 1843, 5, 1002-1012 Biochimica et Biophysica Acta - Molecular Cell Research, 1843, 5, 1002-1012 2014 英語 公開
T. Ishikawa; T. Okada; T. Ishikawa-Fujiwara; T. Todo; Y. Kamei; S. Shigenobu; M. Tanaka; T.L. Saito; J. Yoshimura; S. Morishita; A. Toyoda; Y. Sakaki; Y. Taniguchi; S. Takeda; K. Mori T. Ishikawa; T. Okada; T. Ishikawa-Fujiwara; T. Todo; Y. Kamei; S. Shigenobu; M. Tanaka; T.L. Saito; J. Yoshimura; S. Morishita; A. Toyoda; Y. Sakaki; Y. Taniguchi; S. Takeda; K. Mori ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish Molecular Biology of the Cell, 24, 9, 1387-1395 , 24, 9, 1387-1395 Molecular Biology of the Cell, 24, 9, 1387-1395 2013/05/01 英語 公開
M. Fujita; H. Sasanuma; K.N. Yamamoto; H. Harada; A. Kurosawa; N. Adachi; M. Omura; M. Hiraoka; S. Takeda; K. Hirota M. Fujita; H. Sasanuma; K.N. Yamamoto; H. Harada; A. Kurosawa; N. Adachi; M. Omura; M. Hiraoka; S. Takeda; K. Hirota Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks PLoS ONE, 8, 4 , 8, 4 PLoS ONE, 8, 4 2013 英語 公開
H. Matsui; F. Sato; S. Sato; M. Koike; Y. Taruno; S. Saiki; M. Funayama; H. Ito; Y. Taniguchi; N. Uemura; A. Toyoda; Y. Sakaki; S. Takeda; Y. Uchiyama; N. Hattori; R. Takahashi H. Matsui; F. Sato; S. Sato; M. Koike; Y. Taruno; S. Saiki; M. Funayama; H. Ito; Y. Taniguchi; N. Uemura; A. Toyoda; Y. Sakaki; S. Takeda; Y. Uchiyama; N. Hattori; R. Takahashi ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons FEBS Letters, 587, 9, 1316-1325 , 587, 9, 1316-1325 FEBS Letters, 587, 9, 1316-1325 2013 英語 公開
H. Matsui; R. Gavinio; T. Asano; N. Uemura; H. Ito; Y. Taniguchi; Y. Kobayashi; T. Maki; J. Shen; S. Takeda; K. Uemura; H. Yamakado; R. Takahashi H. Matsui; R. Gavinio; T. Asano; N. Uemura; H. Ito; Y. Taniguchi; Y. Kobayashi; T. Maki; J. Shen; S. Takeda; K. Uemura; H. Yamakado; R. Takahashi PINK1 and parkin complementarily protect dopaminergic neurons in vertebrates PINK1 and parkin complementarily protect dopaminergic neurons in vertebrates Human Molecular Genetics, 22, 12, 2423-2434 , 22, 12, 2423-2434 Human Molecular Genetics, 22, 12, 2423-2434 2013 英語 公開
K. Kikuchi; T. Narita; V.T. Pham; J. Iijima; K. Hirota; I.S. Keka; Mohiuddin; K. Okawa; T. Hori; T. Fukagawa; J. Essers; R. Kanaar; M.C. Whitby; K. Sugasawa; Y. Taniguchi; K. Kitagawa; S. Takeda K. Kikuchi; T. Narita; V.T. Pham; J. Iijima; K. Hirota; I.S. Keka; Mohiuddin; K. Okawa; T. Hori; T. Fukagawa; J. Essers; R. Kanaar; M.C. Whitby; K. Sugasawa; Y. Taniguchi; K. Kitagawa; S. Takeda Structure-specific endonucleases Xpf and Mus81 play overlapping but essential roles in DNA repair by homologous recombination Structure-specific endonucleases Xpf and Mus81 play overlapping but essential roles in DNA repair by homologous recombination Cancer Research, 73, 14, 4362-4371 , 73, 14, 4362-4371 Cancer Research, 73, 14, 4362-4371 2013 英語 公開
S. Lee; X. Liu; S. Takeda; K. Choi S. Lee; X. Liu; S. Takeda; K. Choi Genotoxic potentials and related mechanisms of bisphenol A and other bisphenol compounds: A comparison study employing chicken DT40 cells Genotoxic potentials and related mechanisms of bisphenol A and other bisphenol compounds: A comparison study employing chicken DT40 cells Chemosphere, 93, 2, 434-440 , 93, 2, 434-440 Chemosphere, 93, 2, 434-440 2013 英語 公開
S. Horimoto; S. Ninagawa; T. Okada; H. Koba; T. Sugimoto; Y. Kamiya; K. Kato; S. Takeda; K. Mori S. Horimoto; S. Ninagawa; T. Okada; H. Koba; T. Sugimoto; Y. Kamiya; K. Kato; S. Takeda; K. Mori The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein Journal of Biological Chemistry, 288, 44, 31517-31527 , 288, 44, 31517-31527 Journal of Biological Chemistry, 288, 44, 31517-31527 2013 英語 公開
E.N. Minakawa; H. Yamakado; A. Tanaka; K. Uemura; S. Takeda; R. Takahashi E.N. Minakawa; H. Yamakado; A. Tanaka; K. Uemura; S. Takeda; R. Takahashi Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson\\'s disease, displays mitochondrial dysfunction Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson\\'s disease, displays mitochondrial dysfunction Neuroscience Research, 77, 4, 228-233 , 77, 4, 228-233 Neuroscience Research, 77, 4, 228-233 2013 英語 公開
Y. Maede; H. Shimizu; T. Fukushima; T. Kogame; T. Nakamura; T. Miki; S. Takeda; Y. Pommier; J. Murai Y. Maede; H. Shimizu; T. Fukushima; T. Kogame; T. Nakamura; T. Miki; S. Takeda; Y. Pommier; J. Murai Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel Molecular Cancer Therapeutics, 13, 1, 214-220 , 13, 1, 214-220 Molecular Cancer Therapeutics, 13, 1, 214-220 2013 英語 公開
J. Murai; S.-Y.N. Huang; B.B. Das; A. Renaud; Y. Zhang; J.H. Doroshow; J. Ji; S. Takeda; Y. Pommier J. Murai; S.-Y.N. Huang; B.B. Das; A. Renaud; Y. Zhang; J.H. Doroshow; J. Ji; S. Takeda; Y. Pommier Trapping of PARP1 and PARP2 by clinical PARP inhibitors Trapping of PARP1 and PARP2 by clinical PARP inhibitors Cancer Research, 72, 21, 5588-5599 , 72, 21, 5588-5599 Cancer Research, 72, 21, 5588-5599 2012/11/01 英語 公開
S. Era; T. Abe; H. Arakawa; S. Kobayashi; B. Szakal; Y. Yoshikawa; A. Motegi; S. Takeda; D. Branzei S. Era; T. Abe; H. Arakawa; S. Kobayashi; B. Szakal; Y. Yoshikawa; A. Motegi; S. Takeda; D. Branzei The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment Biochemical and Biophysical Research Communications, 426, 3, 310-316 , 426, 3, 310-316 Biochemical and Biophysical Research Communications, 426, 3, 310-316 2012/09/28 英語 公開
J. Murai; S.-Y.N. Huang; B.B. Das; T.S. Dexheimer; S. Takeda; Y. Pommier J. Murai; S.-Y.N. Huang; B.B. Das; T.S. Dexheimer; S. Takeda; Y. Pommier Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells Journal of Biological Chemistry, 287, 16, 12848-12857 , 287, 16, 12848-12857 Journal of Biological Chemistry, 287, 16, 12848-12857 2012/04/13 英語 公開
G.-L. Moldovan; D. Dejsuphong; M.I.R. Petalcorin; K. Hofmann; S. Takeda; S.J. Boulton; A.D. D'Andrea G.-L. Moldovan; D. Dejsuphong; M.I.R. Petalcorin; K. Hofmann; S. Takeda; S.J. Boulton; A.D. D'Andrea Inhibition of homologous recombination by the PCNA-interacting protein PARI Inhibition of homologous recombination by the PCNA-interacting protein PARI Molecular Cell, 45, 1, 75-86 , 45, 1, 75-86 Molecular Cell, 45, 1, 75-86 2012 英語 公開
X. Liu; J. Lee; K. Ji; S. Takeda; K. Choi X. Liu; J. Lee; K. Ji; S. Takeda; K. Choi Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment Toxicology Letters, 211, 1, 70-76 , 211, 1, 70-76 Toxicology Letters, 211, 1, 70-76 2012 英語 公開
A. Morita; K. Nakahira; T. Hasegawa; K. Uchida; Y. Taniguchi; S. Takeda; A. Toyoda; Y. Sakaki; A. Shimada; H. Takeda; I. Yanagihara A. Morita; K. Nakahira; T. Hasegawa; K. Uchida; Y. Taniguchi; S. Takeda; A. Toyoda; Y. Sakaki; A. Shimada; H. Takeda; I. Yanagihara Establishment and characterization of Roberts syndrome and SC phocomelia model medaka (Oryzias latipes) Establishment and characterization of Roberts syndrome and SC phocomelia model medaka (Oryzias latipes) Development Growth and Differentiation, 54, 5, 588-604 , 54, 5, 588-604 Development Growth and Differentiation, 54, 5, 588-604 2012 英語 公開
M. Kohzaki; M. Chiourea; G. Versini; N. Adachi; S. Takeda; S. Gagos; T.D. Halazonetis M. Kohzaki; M. Chiourea; G. Versini; N. Adachi; S. Takeda; S. Gagos; T.D. Halazonetis The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation Carcinogenesis, 33, 6, 1203-1210 , 33, 6, 1203-1210 Carcinogenesis, 33, 6, 1203-1210 2012 英語 公開
Z. Zeng; A. Sharma; L. Ju; J. Murai; L. Umans; L. Vermeire; Y. Pommier; S. Takeda; D. Huylebroeck; K.W. Caldecott; S.F. El-Khamisy Z. Zeng; A. Sharma; L. Ju; J. Murai; L. Umans; L. Vermeire; Y. Pommier; S. Takeda; D. Huylebroeck; K.W. Caldecott; S.F. El-Khamisy TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 Nucleic Acids Research, 40, 17, 8371-8380 , 40, 17, 8371-8380 Nucleic Acids Research, 40, 17, 8371-8380 2012 英語 公開
J. Murai; K. Yang; D. Dejsuphong; K. Hirota; S. Takeda; A.D. D'Andrea J. Murai; K. Yang; D. Dejsuphong; K. Hirota; S. Takeda; A.D. D'Andrea The USP1/UAF1 complex promotes double-strand break repair through homologous recombination The USP1/UAF1 complex promotes double-strand break repair through homologous recombination Molecular and Cellular Biology, 31, 12, 2462-2469 , 31, 12, 2462-2469 Molecular and Cellular Biology, 31, 12, 2462-2469 2011/06 英語 公開
Qing, Yong;Yamazoe, Mitsuyoshi;Hirota, Kouji;Dejsuphong, Donniphat;Sakai, Wataru;Yamamoto, Kimiyo N;Bishop, Douglas K;Wu, XiaoHua;Takeda, Shunichi Qing, Yong;Yamazoe, Mitsuyoshi;Hirota, Kouji;Dejsuphong, Donniphat;Sakai, Wataru;Yamamoto, Kimiyo N;Bishop, Douglas K;Wu, XiaoHua;Takeda, Shunichi The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. PLoS genetics, 7, 7, e1002148 , 7, 7, e1002148 PLoS genetics, 7, 7, e1002148 2011 英語 公開
J.R. Ridpath; S. Takeda; J.A. Swenberg; J. Nakamura J.R. Ridpath; S. Takeda; J.A. Swenberg; J. Nakamura Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action Environmental and Molecular Mutagenesis, 52, 2, 153-160 , 52, 2, 153-160 Environmental and Molecular Mutagenesis, 52, 2, 153-160 2011 英語 公開
M.N. Paddock; A.T. Bauman; R. Higdon; E. Kolker; S. Takeda; A.M. Scharenberg M.N. Paddock; A.T. Bauman; R. Higdon; E. Kolker; S. Takeda; A.M. Scharenberg Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair DNA Repair, 10, 3, 338-343 , 10, 3, 338-343 DNA Repair, 10, 3, 338-343 2011 英語 公開
V. Quennet; A. Beucher; O. Barton; S. Takeda; M. Löbrich V. Quennet; A. Beucher; O. Barton; S. Takeda; M. Löbrich CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1 CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1 Nucleic Acids Research, 39, 6, 2144-2152 , 39, 6, 2144-2152 Nucleic Acids Research, 39, 6, 2144-2152 2011 英語 公開
K. Ji; K. Choi; J.P. Giesy; J. Musarrat; S. Takeda K. Ji; K. Choi; J.P. Giesy; J. Musarrat; S. Takeda Genotoxicity of several polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDEs, and their mechanisms of toxicity Genotoxicity of several polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDEs, and their mechanisms of toxicity Environmental Science and Technology, 45, 11, 5003-5008 , 45, 11, 5003-5008 Environmental Science and Technology, 45, 11, 5003-5008 2011 英語 公開
S. Takeda; N. Sato; K. Ikimura; H. Nishino; H. Rakugi; R. Morishita S. Takeda; N. Sato; K. Ikimura; H. Nishino; H. Rakugi; R. Morishita Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse Neuroscience, 186, 110-119 , 186, 110-119 Neuroscience, 186, 110-119 2011 英語 公開
K.N. Yamamoto; K. Hirota; K. Kono; S. Takeda; S. Sakamuru; M. Xia; R. Huang; C.P. Austin; K.L. Witt; R.R. Tice K.N. Yamamoto; K. Hirota; K. Kono; S. Takeda; S. Sakamuru; M. Xia; R. Huang; C.P. Austin; K.L. Witt; R.R. Tice Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines Environmental and Molecular Mutagenesis, 52, 7, 547-561 , 52, 7, 547-561 Environmental and Molecular Mutagenesis, 52, 7, 547-561 2011 英語 公開
M. Takaku; T. Tsujita; N. Horikoshi; Y. Takizawa; Y. Qing; K. Hirota; M. Ikura; T. Ikura; S. Takeda; H. Kurumizaka M. Takaku; T. Tsujita; N. Horikoshi; Y. Takizawa; Y. Qing; K. Hirota; M. Ikura; T. Ikura; S. Takeda; H. Kurumizaka Purification of the human SMN-GEMIN2 complex and assessment of its stimulation of RAD51-mediated DNA recombination reactions Purification of the human SMN-GEMIN2 complex and assessment of its stimulation of RAD51-mediated DNA recombination reactions Biochemistry, 50, 32, 6797-6805 , 50, 32, 6797-6805 Biochemistry, 50, 32, 6797-6805 2011 英語 公開
T. Abe; K. Sugimura; Y. Hosono; Y. Takami; M. Akita; A. Yoshimura; S. Tada; T. Nakayama; H. Murofushi; K. Okumura; S. Takeda; M. Horikoshi; M. Seki; T. Enomoto T. Abe; K. Sugimura; Y. Hosono; Y. Takami; M. Akita; A. Yoshimura; S. Tada; T. Nakayama; H. Murofushi; K. Okumura; S. Takeda; M. Horikoshi; M. Seki; T. Enomoto The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates Journal of Biological Chemistry, 286, 35, 30504-30512 , 286, 35, 30504-30512 Journal of Biological Chemistry, 286, 35, 30504-30512 2011 英語 公開
K. Ji; J. Seo; X. Liu; J. Lee; S. Lee; W. Lee; J. Park; J.S. Khim; S. Hong; Y. Choi; W.J. Shim; S. Takeda; J.P. Giesy; K. Choi K. Ji; J. Seo; X. Liu; J. Lee; S. Lee; W. Lee; J. Park; J.S. Khim; S. Hong; Y. Choi; W.J. Shim; S. Takeda; J.P. Giesy; K. Choi Genotoxicity and endocrine-disruption potentials of sediment near an oil spill site: Two years after the hebei spirit oil spill Genotoxicity and endocrine-disruption potentials of sediment near an oil spill site: Two years after the hebei spirit oil spill Environmental Science and Technology, 45, 17, 7481-7488 , 45, 17, 7481-7488 Environmental Science and Technology, 45, 17, 7481-7488 2011 英語 公開
K. Yang; G.-L. Moldovan; P. Vinciguerra; J. Murai; S. Takeda; A.D. D'Andrea K. Yang; G.-L. Moldovan; P. Vinciguerra; J. Murai; S. Takeda; A.D. D'Andrea Regulation of the Fanconi anemia pathway by a SUMO-like delivery network Regulation of the Fanconi anemia pathway by a SUMO-like delivery network Genes and Development, 25, 17, 1847-1858 , 25, 17, 1847-1858 Genes and Development, 25, 17, 1847-1858 2011 英語 公開
S.-I. Chisada; H. Okamoto; Y. Taniguchi; Y. Kimori; A. Toyoda; Y. Sakaki; S. Takeda; Y. Yoshiura S.-I. Chisada; H. Okamoto; Y. Taniguchi; Y. Kimori; A. Toyoda; Y. Sakaki; S. Takeda; Y. Yoshiura Myostatin-deficient medaka exhibit a double-muscling phenotype with hyperplasia and hypertrophy, which occur sequentially during post-hatch development Myostatin-deficient medaka exhibit a double-muscling phenotype with hyperplasia and hypertrophy, which occur sequentially during post-hatch development Developmental Biology, 359, 1, 82-94 , 359, 1, 82-94 Developmental Biology, 359, 1, 82-94 2011 英語 公開
N. Hégarat; E. Smith; G. Nayak; S. Takeda; P.A. Eyers; H. Hochegger N. Hégarat; E. Smith; G. Nayak; S. Takeda; P.A. Eyers; H. Hochegger Aurora A and aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics Aurora A and aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics Journal of Cell Biology, 195, 7, 1103-1113 , 195, 7, 1103-1113 Journal of Cell Biology, 195, 7, 1103-1113 2011 英語 公開
S. Ninagawa; T. Okada; S. Takeda; K. Mori S. Ninagawa; T. Okada; S. Takeda; K. Mori SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line. SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line. Cell structure and function, 36, 2, 187-195 , 36, 2, 187-195 Cell structure and function, 36, 2, 187-195 2011 英語 公開
T. Ishikawa; Y. Taniguchi; T. Okada; S. Takeda; K. Mori T. Ishikawa; Y. Taniguchi; T. Okada; S. Takeda; K. Mori Vertebrate unfolded protein response: mammalian signaling pathways are conserved in Medaka fish. Vertebrate unfolded protein response: mammalian signaling pathways are conserved in Medaka fish. Cell structure and function, 36, 2, 247-259 , 36, 2, 247-259 Cell structure and function, 36, 2, 247-259 2011 英語 公開
T. Narita; T. Tsurimoto; J. Yamamoto; K. Nishihara; K. Ogawa; E. Ohashi; T. Evans; S. Iwai; S. Takeda; K. Hirota T. Narita; T. Tsurimoto; J. Yamamoto; K. Nishihara; K. Ogawa; E. Ohashi; T. Evans; S. Iwai; S. Takeda; K. Hirota Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands Genes to Cells, 15, 12, 1228-1239 , 15, 12, 1228-1239 Genes to Cells, 15, 12, 1228-1239 2010/12 英語 公開
H. Matsui; H. Ito; Y. Taniguchi; S. Takeda; R. Takahashi H. Matsui; H. Ito; Y. Taniguchi; S. Takeda; R. Takahashi Ammonium chloride and tunicamycin are novel toxins for dopaminergic neurons and induce Parkinson\\'s disease-like phenotypes in medaka fish Ammonium chloride and tunicamycin are novel toxins for dopaminergic neurons and induce Parkinson\\'s disease-like phenotypes in medaka fish Journal of Neurochemistry, 115, 5, 1150-1160 , 115, 5, 1150-1160 Journal of Neurochemistry, 115, 5, 1150-1160 2010/12 英語 公開
J. Iijima; Z. Zeng; S. Takeda; Y. Taniguchi J. Iijima; Z. Zeng; S. Takeda; Y. Taniguchi RAP80 acts independently of BRCA1 in repair of topoisomerase II poison-induced DNA damage RAP80 acts independently of BRCA1 in repair of topoisomerase II poison-induced DNA damage Cancer Research, 70, 21, 8467-8474 , 70, 21, 8467-8474 Cancer Research, 70, 21, 8467-8474 2010/11/01 英語 公開
H. Hashimoto; Y. Takami; E. Sonoda; T. Iwasaki; H. Iwano; M. Tachibana; S. Takeda; T. Nakayama; H. Kimura; Y. Shinkai H. Hashimoto; Y. Takami; E. Sonoda; T. Iwasaki; H. Iwano; M. Tachibana; S. Takeda; T. Nakayama; H. Kimura; Y. Shinkai Histone H1 null vertebrate cells exhibit altered nucleosome architecture Histone H1 null vertebrate cells exhibit altered nucleosome architecture Nucleic Acids Research, 38, 11, 3533-3545 , 38, 11, 3533-3545 Nucleic Acids Research, 38, 11, 3533-3545 2010/06 英語 公開
M. Kohzaki; K. Nishihara; K. Hirota; E. Sonoda; M. Yoshimura; S. Ekino; J.E. Butler; M. Watanabe; T.D. Halazonetis; S. Takeda M. Kohzaki; K. Nishihara; K. Hirota; E. Sonoda; M. Yoshimura; S. Ekino; J.E. Butler; M. Watanabe; T.D. Halazonetis; S. Takeda DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken DNA polymerases ν and θ are required for efficient immunoglobulin V gene diversification in chicken Journal of Cell Biology, 189, 7, 1117-1127 , 189, 7, 1117-1127 Journal of Cell Biology, 189, 7, 1117-1127 2010 英語 公開
K. Nakamura; T. Kogame; H. Oshiumi; A. Shinohara; Y. Sumitomo; K. Agama; Y. Pommier; K.M. Tsutsui; K. Tsutsui; E. Hartsuiker; T. Ogi; S. Takeda; Y. Taniguchi K. Nakamura; T. Kogame; H. Oshiumi; A. Shinohara; Y. Sumitomo; K. Agama; Y. Pommier; K.M. Tsutsui; K. Tsutsui; E. Hartsuiker; T. Ogi; S. Takeda; Y. Taniguchi Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair PLoS Genetics, 6, 1 , 6, 1 PLoS Genetics, 6, 1 2010 英語 公開
M. Schartl; B. Wilde; J.A.G.C. Laisney; Y. Taniguchi; S. Takeda; S. Meierjohann M. Schartl; B. Wilde; J.A.G.C. Laisney; Y. Taniguchi; S. Takeda; S. Meierjohann A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies Journal of Investigative Dermatology, 130, 1, 249-258 , 130, 1, 249-258 Journal of Investigative Dermatology, 130, 1, 249-258 2010 英語 公開
H. Matsui; Y. Taniguchi; H. Inoue; Y. Kobayashi; Y. Sakaki; A. Toyoda; K. Uemura; D. Kobayashi; S. Takeda; R. Takahashi H. Matsui; Y. Taniguchi; H. Inoue; Y. Kobayashi; Y. Sakaki; A. Toyoda; K. Uemura; D. Kobayashi; S. Takeda; R. Takahashi Loss of PINK1 in medaka fish (Oryzias latipes) causes late-onset decrease in spontaneous movement Loss of PINK1 in medaka fish (Oryzias latipes) causes late-onset decrease in spontaneous movement Neuroscience Research, 66, 2, 151-161 , 66, 2, 151-161 Neuroscience Research, 66, 2, 151-161 2010 英語 公開
E. Bourke; J.A.L. Brown; S. Takeda; H. Hochegger; C.G. Morrison E. Bourke; J.A.L. Brown; S. Takeda; H. Hochegger; C.G. Morrison DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2 DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2 Oncogene, 29, 4, 616-624 , 29, 4, 616-624 Oncogene, 29, 4, 616-624 2010 英語 公開
K. Asagoshi; K. Tano; P.D. Chastain II; N. Adachi; E. Sonoda; K. Kikuchi; H. Koyama; K. Nagata; D.G. Kaufman; S. Takeda; S.H. Wilson; M. Watanabe; J.A. Swenberg; J. Nakamura K. Asagoshi; K. Tano; P.D. Chastain II; N. Adachi; E. Sonoda; K. Kikuchi; H. Koyama; K. Nagata; D.G. Kaufman; S. Takeda; S.H. Wilson; M. Watanabe; J.A. Swenberg; J. Nakamura FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells Molecular Cancer Research, 8, 2, 204-215 , 8, 2, 204-215 Molecular Cancer Research, 8, 2, 204-215 2010 英語 公開
X. Wang; K. Takenaka; S. Takeda X. Wang; K. Takenaka; S. Takeda PTIP promotes DNA double-strand break repair through homologous recombination PTIP promotes DNA double-strand break repair through homologous recombination Genes to Cells, 15, 3, 243-254 , 15, 3, 243-254 Genes to Cells, 15, 3, 243-254 2010 英語 公開
K. Hara; H. Hashimoto; Y. Murakumo; S. Kobayashi; T. Kogame; S. Unzai; S. Akashi; S. Takeda; T. Shimizu; M. Sato K. Hara; H. Hashimoto; Y. Murakumo; S. Kobayashi; T. Kogame; S. Unzai; S. Akashi; S. Takeda; T. Shimizu; M. Sato Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase ζ and REV1 Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase ζ and REV1 Journal of Biological Chemistry, 285, 16, 12299-12307 , 285, 16, 12299-12307 Journal of Biological Chemistry, 285, 16, 12299-12307 2010 英語 公開
H. Wang; X. Zhang; P. Wang; X. Yu; J. Essers; D. Chen; R. Kanaar; S. Takeda; Y. Wang H. Wang; X. Zhang; P. Wang; X. Yu; J. Essers; D. Chen; R. Kanaar; S. Takeda; Y. Wang Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation Nucleic Acids Research, 38, 10, 3245-3251 , 38, 10, 3245-3251 Nucleic Acids Research, 38, 10, 3245-3251 2010 英語 公開
M.N. Paddock; B.D. Buelow; S. Takeda; A.M. Scharenberg M.N. Paddock; B.D. Buelow; S. Takeda; A.M. Scharenberg The BRCT domain of PARP-1 is required for immunoglobulin gene conversion The BRCT domain of PARP-1 is required for immunoglobulin gene conversion PLoS Biology, 8, 7 , 8, 7 PLoS Biology, 8, 7 2010 英語 公開
Y. Takizawa; Y. Qing; M. Takaku; T. Ishida; Y. Morozumi; T. Tsujita; T. Kogame; K. Hirota; M. Takahashi; T. Shibata; H. Kurumizaka; S. Takeda Y. Takizawa; Y. Qing; M. Takaku; T. Ishida; Y. Morozumi; T. Tsujita; T. Kogame; K. Hirota; M. Takahashi; T. Shibata; H. Kurumizaka; S. Takeda GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination Nucleic Acids Research, 38, 15, 5059-5074 , 38, 15, 5059-5074 Nucleic Acids Research, 38, 15, 5059-5074 2010 英語 公開
H. Matsui; H. Ito; Y. Taniguchi; H. Inoue; S. Takeda; R. Takahashi H. Matsui; H. Ito; Y. Taniguchi; H. Inoue; S. Takeda; R. Takahashi Proteasome inhibition in medaka brain induces the features of Parkinson\\'s disease Proteasome inhibition in medaka brain induces the features of Parkinson\\'s disease Journal of Neurochemistry, 115, 1, 178-187 , 115, 1, 178-187 Journal of Neurochemistry, 115, 1, 178-187 2010 英語 公開
S. Jurado; I. Smyth; B. van Denderen; N. Tenis; A. Hammet; K. Hewitt; J.-L. Ng; C.J. McNees; S.V. Kozlov; H. Oka; M. Kobayashi; L.A. Conlan; T.J. Cole; K.-I. Yamamoto; Y. Taniguchi; S. Takeda; M.F. Lavin; J. Heierhorst S. Jurado; I. Smyth; B. van Denderen; N. Tenis; A. Hammet; K. Hewitt; J.-L. Ng; C.J. McNees; S.V. Kozlov; H. Oka; M. Kobayashi; L.A. Conlan; T.J. Cole; K.-I. Yamamoto; Y. Taniguchi; S. Takeda; M.F. Lavin; J. Heierhorst Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis PLoS Genetics, 6, 10, 1-13 , 6, 10, 1-13 PLoS Genetics, 6, 10, 1-13 2010 英語 公開
K. Hirota; E. Sonoda; T. Kawamoto; A. Motegi; C. Masutani; F. Hanaoka; D. Szüts; S. Iwai; J.E. Sale; A. Lehmann; S. Takeda K. Hirota; E. Sonoda; T. Kawamoto; A. Motegi; C. Masutani; F. Hanaoka; D. Szüts; S. Iwai; J.E. Sale; A. Lehmann; S. Takeda Simultaneous disruption of two DNA polymerases, Polη and Polζ, in avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions Simultaneous disruption of two DNA polymerases, Polη and Polζ, in avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions PLoS Genetics, 6, 10, 1-13 , 6, 10, 1-13 PLoS Genetics, 6, 10, 1-13 2010 英語 公開
T.J. Evans; K.N. Yamamoto; K. Hirota; S. Takeda T.J. Evans; K.N. Yamamoto; K. Hirota; S. Takeda Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity DNA Repair, 9, 12, 1292-1298 , 9, 12, 1292-1298 DNA Repair, 9, 12, 1292-1298 2010 英語 公開
A.M. Luke; P.D. Chastain; B.F. Pachkowski; V. Afonin; S. Takeda; D.G. Kaufman; J.A. Swenberg; J. Nakamura A.M. Luke; P.D. Chastain; B.F. Pachkowski; V. Afonin; S. Takeda; D.G. Kaufman; J.A. Swenberg; J. Nakamura Accumulation of true single strand breaks and AP sites in base excision repair deficient cells Accumulation of true single strand breaks and AP sites in base excision repair deficient cells Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 694, 1-2, 65-71 , 694, 1-2, 65-71 Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 694, 1-2, 65-71 2010 英語 公開
S. Jurado; I. Smyth; B. van Denderen; N. Tenis; A. Hammet; K. Hewitt; J.L. Ng; C.J. McNees; S.V. Kozlov; H. Oka; M. Kobayashi; L.A. Conlan; T.J. Cole; K. Yamamoto; Y. Taniguchi; S. Takeda; M.F. Lavin; J. Heierhorst S. Jurado; I. Smyth; B. van Denderen; N. Tenis; A. Hammet; K. Hewitt; J.L. Ng; C.J. McNees; S.V. Kozlov; H. Oka; M. Kobayashi; L.A. Conlan; T.J. Cole; K. Yamamoto; Y. Taniguchi; S. Takeda; M.F. Lavin; J. Heierhorst Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis. Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis. PLoS genetics, 6, 10, e1001170 , 6, 10, e1001170 PLoS genetics, 6, 10, e1001170 2010 英語 公開
B.F. Pachkowski; K. Tano; V. Afonin; R.H. Elder; S. Takeda; M. Watanabe; J.A. Swenberg; J. Nakamura B.F. Pachkowski; K. Tano; V. Afonin; R.H. Elder; S. Takeda; M. Watanabe; J.A. Swenberg; J. Nakamura Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 671, 1-2, 93-99 , 671, 1-2, 93-99 Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 671, 1-2, 93-99 2009/12/01 英語 公開
A. Motegi; Y. Murakawa; S. Takeda A. Motegi; Y. Murakawa; S. Takeda The vital link between the ubiquitin-proteasome pathway and DNA repair: Impact on cancer therapy The vital link between the ubiquitin-proteasome pathway and DNA repair: Impact on cancer therapy Cancer Letters, 283, 1, 1-9 , 283, 1, 1-9 Cancer Letters, 283, 1, 1-9 2009/09/28 英語 公開
M. Nakahara; E. Sonoda; K. Nojima; J.E. Sale; K. Takenaka; K. Kikuchi; Y. Taniguchi; K. Nakamura; Y. Sumitomo; R.T. Bree; N.F. Lowndes; S. Takeda M. Nakahara; E. Sonoda; K. Nojima; J.E. Sale; K. Takenaka; K. Kikuchi; Y. Taniguchi; K. Nakamura; Y. Sumitomo; R.T. Bree; N.F. Lowndes; S. Takeda Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig V in chicken B lymphocytes Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig V in chicken B lymphocytes PLoS Genetics, 5, 1 , 5, 1 PLoS Genetics, 5, 1 2009 英語 公開
E. Smith; D. Dejsuphong; A. Balestrini; M. Hampel; C. Lenz; S. Takeda; A. Vindigni; V. Costanzo E. Smith; D. Dejsuphong; A. Balestrini; M. Hampel; C. Lenz; S. Takeda; A. Vindigni; V. Costanzo An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63 An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63 Nature Cell Biology, 11, 3, 278-285 , 11, 3, 278-285 Nature Cell Biology, 11, 3, 278-285 2009 英語 公開
X. Kong; A.R. Ball; E. Sonoda; J. Feng; S. Takeda; T. Fukagawa; T.J. Yen; K. Yokomori X. Kong; A.R. Ball; E. Sonoda; J. Feng; S. Takeda; T. Fukagawa; T.J. Yen; K. Yokomori Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells Cohesin associates with spindle poles in a mitosis-specific manner and functions in spindle assembly in vertebrate cells Molecular Biology of the Cell, 20, 5, 1289-1301 , 20, 5, 1289-1301 Molecular Biology of the Cell, 20, 5, 1289-1301 2009 英語 公開
J. Suzuki; K. Yamaguchi; M. Kajikawa; K. Ichiyanagi; N. Adachi; H. Koyama; S. Takeda; N. Okada J. Suzuki; K. Yamaguchi; M. Kajikawa; K. Ichiyanagi; N. Adachi; H. Koyama; S. Takeda; N. Okada Genetic evidence that the non-homologous end-joining repair pathway is involved in LINE retrotransposition Genetic evidence that the non-homologous end-joining repair pathway is involved in LINE retrotransposition PLoS Genetics, 5, 4 , 5, 4 PLoS Genetics, 5, 4 2009 英語 公開
T. Kawasaki; K. Saito; K. Mitsui; M. Ikawa; M. Yamashita; Y. Taniguchi; S. Takeda; K. Mitani; N. Sakai T. Kawasaki; K. Saito; K. Mitsui; M. Ikawa; M. Yamashita; Y. Taniguchi; S. Takeda; K. Mitani; N. Sakai Introduction of a foreign gene into zebrafish and medaka cells using adenoviral vectors Introduction of a foreign gene into zebrafish and medaka cells using adenoviral vectors Zebrafish, 6, 3, 253-258 , 6, 3, 253-258 Zebrafish, 6, 3, 253-258 2009 英語 公開
H. Matsui; Y. Taniguchi; H. Inoue; K. Uemura; S. Takeda; R. Takahashi H. Matsui; Y. Taniguchi; H. Inoue; K. Uemura; S. Takeda; R. Takahashi A chemical neurotoxin, MPTP induces Parkinson\\'s disease like phenotype, movement disorders and persistent loss of dopamine neurons in medaka fish A chemical neurotoxin, MPTP induces Parkinson\\'s disease like phenotype, movement disorders and persistent loss of dopamine neurons in medaka fish Neuroscience Research, 65, 3, 263-271 , 65, 3, 263-271 Neuroscience Research, 65, 3, 263-271 2009 英語 公開
K. Kikuchi; H.I. Abdel-Aziz; Y. Taniguchi; M. Yamazoe; S. Takeda; K. Hirota K. Kikuchi; H.I. Abdel-Aziz; Y. Taniguchi; M. Yamazoe; S. Takeda; K. Hirota Bloom DNA helicase facilitates homologous recombination between diverged homologous sequences Bloom DNA helicase facilitates homologous recombination between diverged homologous sequences Journal of Biological Chemistry, 284, 39, 26360-26367 , 284, 39, 26360-26367 Journal of Biological Chemistry, 284, 39, 26360-26367 2009 英語 公開
K. Ji; T. Kogame; K. Choi; X. Wang; J. Lee; Y. Taniguchi; S. Takeda K. Ji; T. Kogame; K. Choi; X. Wang; J. Lee; Y. Taniguchi; S. Takeda A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants Environmental Health Perspectives, 117, 11, 1737-1744 , 117, 11, 1737-1744 Environmental Health Perspectives, 117, 11, 1737-1744 2009 英語 公開
A. Motegi; S. Takeda A. Motegi; S. Takeda [Function of homologous recombination-mediated DNA repair]. [Function of homologous recombination-mediated DNA repair]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 450-458 , 54, 4 Suppl, 450-458 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54, 4 Suppl, 450-458 2009 英語 公開
T. Abe; M. Ishiai; Y. Hosono; A. Yoshimura; S. Tada; N. Adachi; H. Koyama; M. Takata; S. Takeda; T. Enomoto; M. Seki T. Abe; M. Ishiai; Y. Hosono; A. Yoshimura; S. Tada; N. Adachi; H. Koyama; M. Takata; S. Takeda; T. Enomoto; M. Seki KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation Cellular Signalling, 20, 11, 1978-1985 , 20, 11, 1978-1985 Cellular Signalling, 20, 11, 1978-1985 2008/11 英語 公開
P.U. Devi; H. Utsumi; M. Takata; S. Takeda P.U. Devi; H. Utsumi; M. Takata; S. Takeda Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A Indian Journal of Experimental Biology, 46, 6, 437-442 , 46, 6, 437-442 Indian Journal of Experimental Biology, 46, 6, 437-442 2008/06 英語 公開
V. Faure; T. Wenner; C. Cooley; E. Bourke; C.J. Farr; S. Takeda; C.G. Morrison V. Faure; T. Wenner; C. Cooley; E. Bourke; C.J. Farr; S. Takeda; C.G. Morrison Ku70 prevents genome instability resulting from heterozygosity of the telomerase RNA component in a vertebrate tumour line Ku70 prevents genome instability resulting from heterozygosity of the telomerase RNA component in a vertebrate tumour line DNA Repair, 7, 5, 713-724 , 7, 5, 713-724 DNA Repair, 7, 5, 713-724 2008 英語 公開
H. Oka; W. Sakai; E. Sonoda; J. Nakamura; K. Asagoshi; S.H. Wilson; M. Kobayashi; K. Yamamoto; J. Heierhorst; S. Takeda; Y. Taniguchi H. Oka; W. Sakai; E. Sonoda; J. Nakamura; K. Asagoshi; S.H. Wilson; M. Kobayashi; K. Yamamoto; J. Heierhorst; S. Takeda; Y. Taniguchi DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion Biochemical and Biophysical Research Communications, 371, 2, 225-229 , 371, 2, 225-229 Biochemical and Biophysical Research Communications, 371, 2, 225-229 2008 英語 公開
D. Takeuchi; N. Sato; M. Shimamura; H. Kurinami; S. Takeda; M. Shinohara; S. Suzuki; M. Kojima; T. Ogihara; R. Morishita D. Takeuchi; N. Sato; M. Shimamura; H. Kurinami; S. Takeda; M. Shinohara; S. Suzuki; M. Kojima; T. Ogihara; R. Morishita Alleviation of Aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model Alleviation of Aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model Gene Therapy, 15, 8, 561-571 , 15, 8, 561-571 Gene Therapy, 15, 8, 561-571 2008 英語 公開
D.J. Richard; E. Bolderson; L. Cubeddu; R.I.M. Wadsworth; K. Savage; G.G. Sharma; M.L. Nicolette; S. Tsvetanov; M.J. McIlwraith; R.K. Pandita; S. Takeda; R.T. Hay; J. Gautier; S.C. West; T.T. Paull; T.K. Pandita; M.F. White; K.K. Khanna D.J. Richard; E. Bolderson; L. Cubeddu; R.I.M. Wadsworth; K. Savage; G.G. Sharma; M.L. Nicolette; S. Tsvetanov; M.J. McIlwraith; R.K. Pandita; S. Takeda; R.T. Hay; J. Gautier; S.C. West; T.T. Paull; T.K. Pandita; M.F. White; K.K. Khanna Single-stranded DNA-binding protein hSSB1 is critical for genomic stability Single-stranded DNA-binding protein hSSB1 is critical for genomic stability Nature, 453, 7195, 677-681 , 453, 7195, 677-681 Nature, 453, 7195, 677-681 2008 英語 公開
A. Saberi; M. Nakahara; J.E. Sale; K. Kikuchi; H. Arakawa; J.-M. Buerstedde; K. Yamamoto; S. Takeda; E. Sonoda A. Saberi; M. Nakahara; J.E. Sale; K. Kikuchi; H. Arakawa; J.-M. Buerstedde; K. Yamamoto; S. Takeda; E. Sonoda The 9-1-1 DNA clamp is required for immunoglobulin gene conversion The 9-1-1 DNA clamp is required for immunoglobulin gene conversion Molecular and Cellular Biology, 28, 19, 6113-6122 , 28, 19, 6113-6122 Molecular and Cellular Biology, 28, 19, 6113-6122 2008 英語 公開
H. Oka; W. Sakai; E. Sonoda; J. Nakamura; K. Asagoshi; S.H. Wilson; M. Kobayashi; K. Yamamoto; J. Heierhorst; S. Takeda; Y. Taniguchi H. Oka; W. Sakai; E. Sonoda; J. Nakamura; K. Asagoshi; S.H. Wilson; M. Kobayashi; K. Yamamoto; J. Heierhorst; S. Takeda; Y. Taniguchi Corrigendum to "DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion" [Biochem. Biophys. Res. Commun. 371 (2008) 225-229] (DOI:10.1016/j.bbrc.2008.04.052) Corrigendum to "DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion" [Biochem. Biophys. Res. Commun. 371 (2008) 225-229] (DOI:10.1016/j.bbrc.2008.04.052) Biochemical and Biophysical Research Communications, 377, 1, 326- , 377, 1, 326- Biochemical and Biophysical Research Communications, 377, 1, 326- 2008 英語 公開
H. Hochegger; S. Takeda; T. Hunt H. Hochegger; S. Takeda; T. Hunt Cyclin-dependent kinases and cell-cycle transitions: Does one fit all? Cyclin-dependent kinases and cell-cycle transitions: Does one fit all? Nature Reviews Molecular Cell Biology, 9, 11, 910-916 , 9, 11, 910-916 Nature Reviews Molecular Cell Biology, 9, 11, 910-916 2008 英語 公開
K. Sugimura; S.-I. Takebayashi; H. Taguchi; S. Takeda; K. Okumura K. Sugimura; S.-I. Takebayashi; H. Taguchi; S. Takeda; K. Okumura PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA Journal of Cell Biology, 183, 7, 1203-1212 , 183, 7, 1203-1212 Journal of Cell Biology, 183, 7, 1203-1212 2008 英語 公開
M. Kohzaki; A. Hatanaka; E. Sonoda; M. Yamazoe; K. Kikuchi; V.T. Nguyen; D. Szüts; J.E. Sale; H. Shinagawa; M. Watanabe; S. Takeda M. Kohzaki; A. Hatanaka; E. Sonoda; M. Yamazoe; K. Kikuchi; V.T. Nguyen; D. Szüts; J.E. Sale; H. Shinagawa; M. Watanabe; S. Takeda Cooperative roles of vertebrate Fbh1 and Blm DNA helicases in avoidance of crossovers during recombination initiated by replication fork collapse Cooperative roles of vertebrate Fbh1 and Blm DNA helicases in avoidance of crossovers during recombination initiated by replication fork collapse Molecular and Cellular Biology, 27, 8, 2812-2820 , 27, 8, 2812-2820 Molecular and Cellular Biology, 27, 8, 2812-2820 2007/04 英語 公開
E. Sonoda; G.Y. Zhao; M. Kohzaki; P.K. Dhar; K. Kikuchi; C. Redon; D.R. Pilch; W.M. Bonner; A. Nakano; M. Watanabe; T. Nakayama; S. Takeda; Y. Takami E. Sonoda; G.Y. Zhao; M. Kohzaki; P.K. Dhar; K. Kikuchi; C. Redon; D.R. Pilch; W.M. Bonner; A. Nakano; M. Watanabe; T. Nakayama; S. Takeda; Y. Takami Collaborative roles of γH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair Collaborative roles of γH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair DNA Repair, 6, 3, 280-292 , 6, 3, 280-292 DNA Repair, 6, 3, 280-292 2007/03/01 英語 公開
P. Danoy; E. Sonoda; M. Lathrop; S. Takeda; F. Matsuda P. Danoy; E. Sonoda; M. Lathrop; S. Takeda; F. Matsuda A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage Biochemical and Biophysical Research Communications, 352, 3, 763-768 , 352, 3, 763-768 Biochemical and Biophysical Research Communications, 352, 3, 763-768 2007 英語 公開
B.S.S. Rao; K. Tano; S. Takeda; H. Utsumi B.S.S. Rao; K. Tano; S. Takeda; H. Utsumi Split dose recovery studies using homologous recombination deficient gene knockout chicken B lymphocyte cells Split dose recovery studies using homologous recombination deficient gene knockout chicken B lymphocyte cells Journal of Radiation Research, 48, 1, 77-85 , 48, 1, 77-85 Journal of Radiation Research, 48, 1, 77-85 2007 英語 公開
A. Saberi; H. Hochegger; D. Szuts; L. Lan; A. Yasui; J.E. Sale; Y. Taniguchi; Y. Murakawa; W. Zeng; K. Yokomori; T. Helleday; H. Teraoka; H. Arakawa; J.-M. Buerstedde; S. Takeda A. Saberi; H. Hochegger; D. Szuts; L. Lan; A. Yasui; J.E. Sale; Y. Taniguchi; Y. Murakawa; W. Zeng; K. Yokomori; T. Helleday; H. Teraoka; H. Arakawa; J.-M. Buerstedde; S. Takeda RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair Molecular and Cellular Biology, 27, 7, 2562-2571 , 27, 7, 2562-2571 Molecular and Cellular Biology, 27, 7, 2562-2571 2007 英語 公開
G.Y. Zhao; E. Sonoda; L.J. Barber; H. Oka; Y. Murakawa; K. Yamada; T. Ikura; X. Wang; M. Kobayashi; K. Yamamoto; S.J. Boulton; S. Takeda G.Y. Zhao; E. Sonoda; L.J. Barber; H. Oka; Y. Murakawa; K. Yamada; T. Ikura; X. Wang; M. Kobayashi; K. Yamamoto; S.J. Boulton; S. Takeda A Critical Role for the Ubiquitin-Conjugating Enzyme Ubc13 in Initiating Homologous Recombination A Critical Role for the Ubiquitin-Conjugating Enzyme Ubc13 in Initiating Homologous Recombination Molecular Cell, 25, 5, 663-675 , 25, 5, 663-675 Molecular Cell, 25, 5, 663-675 2007 英語 公開
A.J.L. Cook; J.M. Raftery; K.K.E. Lau; A. Jessup; R.S. Harris; S. Takeda; C.J. Jolly A.J.L. Cook; J.M. Raftery; K.K.E. Lau; A. Jessup; R.S. Harris; S. Takeda; C.J. Jolly DNA-dependent protein kinase inhibits AID-induced antibody gene conversion DNA-dependent protein kinase inhibits AID-induced antibody gene conversion PLoS Biology, 5, 4, 792-799 , 5, 4, 792-799 PLoS Biology, 5, 4, 792-799 2007 英語 公開
K. Tano; J. Nakamura; K. Asagoshi; H. Arakawa; E. Sonoda; E.K. Braithwaite; R. Prasad; J.-M. Buerstedde; S. Takeda; M. Watanabe; S.H. Wilson K. Tano; J. Nakamura; K. Asagoshi; H. Arakawa; E. Sonoda; E.K. Braithwaite; R. Prasad; J.-M. Buerstedde; S. Takeda; M. Watanabe; S.H. Wilson Interplay between DNA polymerases β and λ in repair of oxidation DNA damage in chicken DT40 cells Interplay between DNA polymerases β and λ in repair of oxidation DNA damage in chicken DT40 cells DNA Repair, 6, 6, 869-875 , 6, 6, 869-875 DNA Repair, 6, 6, 869-875 2007 英語 公開
H. Hochegger; D. Dejsuphong; E. Sonoda; A. Saberi; E. Rajendra; J. Kirk; T. Hunt; S. Takeda H. Hochegger; D. Dejsuphong; E. Sonoda; A. Saberi; E. Rajendra; J. Kirk; T. Hunt; S. Takeda An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells Journal of Cell Biology, 178, 2, 257-268 , 178, 2, 257-268 Journal of Cell Biology, 178, 2, 257-268 2007 英語 公開
A.E.O. Fisher; H. Hochegger; S. Takeda; K.W. Caldecott A.E.O. Fisher; H. Hochegger; S. Takeda; K.W. Caldecott Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase Molecular and Cellular Biology, 27, 15, 5597-5605 , 27, 15, 5597-5605 Molecular and Cellular Biology, 27, 15, 5597-5605 2007 英語 公開
M. Kinoshita; S. Takeda M. Kinoshita; S. Takeda Connecting the Dots between Septins and the DNA Damage Checkpoint Connecting the Dots between Septins and the DNA Damage Checkpoint Cell, 130, 5, 777-779 , 130, 5, 777-779 Cell, 130, 5, 777-779 2007 英語 公開
Y. Murakawa; E. Sonoda; L.J. Barber; W. Zeng; K. Yokomori; H. Kimura; A. Niimi; A. Lehmann; Y.Z. Guang; H. Hochegger; S.J. Boulton; S. Takeda Y. Murakawa; E. Sonoda; L.J. Barber; W. Zeng; K. Yokomori; H. Kimura; A. Niimi; A. Lehmann; Y.Z. Guang; H. Hochegger; S.J. Boulton; S. Takeda Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells Cancer Research, 67, 18, 8536-8543 , 67, 18, 8536-8543 Cancer Research, 67, 18, 8536-8543 2007 英語 公開
A.J. Cook; J.M. Raftery; K.K. Lau; A. Jessup; R.S. Harris; S. Takeda; C.J. Jolly A.J. Cook; J.M. Raftery; K.K. Lau; A. Jessup; R.S. Harris; S. Takeda; C.J. Jolly DNA-dependent protein kinase inhibits AID-induced antibody gene conversion. DNA-dependent protein kinase inhibits AID-induced antibody gene conversion. PLoS biology, 5, 4, e80 , 5, 4, e80 PLoS biology, 5, 4, e80 2007 英語 公開
T. Ikura; S. Tashiro; A. Kakino; H. Shima; N. Jacob; R. Amunugama; K. Yoder; S. Izumi; I. Kuraoka; K. Tanaka; H. Kimura; M. Ikura; S. Nishikubo; T. Ito; A. Muto; K. Miyagawa; S. Takeda; R. Fishel; K. Igarashi; K. Kamiya T. Ikura; S. Tashiro; A. Kakino; H. Shima; N. Jacob; R. Amunugama; K. Yoder; S. Izumi; I. Kuraoka; K. Tanaka; H. Kimura; M. Ikura; S. Nishikubo; T. Ito; A. Muto; K. Miyagawa; S. Takeda; R. Fishel; K. Igarashi; K. Kamiya DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics Molecular and Cellular Biology, 27, 20, 7028-7040 , 27, 20, 7028-7040 Molecular and Cellular Biology, 27, 20, 7028-7040 2007 英語 公開
M. Otsuki; M. Seki; E. Inoue; A. Yoshimura; G. Kato; S. Yamanouchi; Y.-I. Kawabe; S. Tada; A. Shinohara; J.-I. Komura; T. Ono; S. Takeda; Y. Ishii; T. Enomoto M. Otsuki; M. Seki; E. Inoue; A. Yoshimura; G. Kato; S. Yamanouchi; Y.-I. Kawabe; S. Tada; A. Shinohara; J.-I. Komura; T. Ono; S. Takeda; Y. Ishii; T. Enomoto Functional interactions between BLM and XRCC3 in the cell Functional interactions between BLM and XRCC3 in the cell Journal of Cell Biology, 179, 1, 53-63 , 179, 1, 53-63 Journal of Cell Biology, 179, 1, 53-63 2007 英語 公開
H. Hashimoto; E. Sonoda; Y. Takami; H. Kimura; T. Nakayama; M. Tachibana; S. Takeda; Y. Shinkai H. Hashimoto; E. Sonoda; Y. Takami; H. Kimura; T. Nakayama; M. Tachibana; S. Takeda; Y. Shinkai Histone H1 variant, H1R is involved in DNA damage response Histone H1 variant, H1R is involved in DNA damage response DNA Repair, 6, 11, 1584-1595 , 6, 11, 1584-1595 DNA Repair, 6, 11, 1584-1595 2007 英語 公開
R.W. Martin; B.J. Orelli; M. Yamazoe; A.J. Minn; S. Takeda; D.K. Bishop R.W. Martin; B.J. Orelli; M. Yamazoe; A.J. Minn; S. Takeda; D.K. Bishop RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors Cancer Research, 67, 20, 9658-9665 , 67, 20, 9658-9665 Cancer Research, 67, 20, 9658-9665 2007 英語 公開
S. Takeda; K. Nakamura; Y. Taniguchi; T.T. Paull S. Takeda; K. Nakamura; Y. Taniguchi; T.T. Paull Ctp1/CtIP and the MRN Complex Collaborate in the Initial Steps of Homologous Recombination Ctp1/CtIP and the MRN Complex Collaborate in the Initial Steps of Homologous Recombination Molecular Cell, 28, 3, 351-352 , 28, 3, 351-352 Molecular Cell, 28, 3, 351-352 2007 英語 公開
M. Wakasugi; K. Matsuura; A. Nagasawa; D. Fu; H. Shimizu; K.-i. Yamamoto; S. Takeda; T. Matsunaga M. Wakasugi; K. Matsuura; A. Nagasawa; D. Fu; H. Shimizu; K.-i. Yamamoto; S. Takeda; T. Matsunaga DDB1 gene disruption causes a severe growth defect and apoptosis in chicken DT40 cells DDB1 gene disruption causes a severe growth defect and apoptosis in chicken DT40 cells Biochemical and Biophysical Research Communications, 364, 4, 771-777 , 364, 4, 771-777 Biochemical and Biophysical Research Communications, 364, 4, 771-777 2007 英語 公開
J.R. Ridpath; A. Nakamura; K. Tano; A.M. Luke; E. Sonoda; H. Arakawa; J.-M. Buerstedde; D.A.F. Gillespie; J.E. Sale; M. Yamazoe; D.K. Bishop; M. Takata; S. Takeda; M. Watanabe; J.A. Swenberg; J. Nakamura J.R. Ridpath; A. Nakamura; K. Tano; A.M. Luke; E. Sonoda; H. Arakawa; J.-M. Buerstedde; D.A.F. Gillespie; J.E. Sale; M. Yamazoe; D.K. Bishop; M. Takata; S. Takeda; M. Watanabe; J.A. Swenberg; J. Nakamura Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde Cancer Research, 67, 23, 11117-11122 , 67, 23, 11117-11122 Cancer Research, 67, 23, 11117-11122 2007 英語 公開
K. Nakamura; W. Sakai; T. Kawamoto; R.T. Bree; N.F. Lowndes; S. Takeda; Y. Taniguchi K. Nakamura; W. Sakai; T. Kawamoto; R.T. Bree; N.F. Lowndes; S. Takeda; Y. Taniguchi Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks Genetic dissection of vertebrate 53BP1: A major role in non-homologous end joining of DNA double strand breaks DNA Repair, 5, 6, 741-749 , 5, 6, 741-749 DNA Repair, 5, 6, 741-749 2006/06/10 英語 公開
S. Sasaki; M. Sato; Y. Katsura; A. Kurimasa; D.J. Chen; S. Takeda; H. Kuwano; J. Yokota; T. Kohno S. Sasaki; M. Sato; Y. Katsura; A. Kurimasa; D.J. Chen; S. Takeda; H. Kuwano; J. Yokota; T. Kohno Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells Rapid assessment of two major repair activities against DNA double-strand breaks in vertebrate cells Biochemical and Biophysical Research Communications, 339, 2, 583-590 , 339, 2, 583-590 Biochemical and Biophysical Research Communications, 339, 2, 583-590 2006 英語 公開
X. Wu; K. Takenaka; E. Sonoda; H. Hochegger; S. Kawanishi; T. Kawamoto; S. Takeda; M. Yamazoe X. Wu; K. Takenaka; E. Sonoda; H. Hochegger; S. Kawanishi; T. Kawamoto; S. Takeda; M. Yamazoe Critical roles for polymerase ζ in cellular tolerance to nitric oxide-induced DNA damage Critical roles for polymerase ζ in cellular tolerance to nitric oxide-induced DNA damage Cancer Research, 66, 2, 748-754 , 66, 2, 748-754 Cancer Research, 66, 2, 748-754 2006 英語 公開
K. Takenaka; T. Ogi; T. Okada; E. Sonoda; C. Guo; E.C. Friedberg; S. Takeda K. Takenaka; T. Ogi; T. Okada; E. Sonoda; C. Guo; E.C. Friedberg; S. Takeda Involvement of vertebrate Polκ in translesion DNA synthesis across DNA monoalkylation damage Involvement of vertebrate Polκ in translesion DNA synthesis across DNA monoalkylation damage Journal of Biological Chemistry, 281, 4, 2000-2004 , 281, 4, 2000-2004 Journal of Biological Chemistry, 281, 4, 2000-2004 2006 英語 公開
H. Hochegger; D. Dejsuphong; T. Fukushima; C. Morrison; E. Sonoda; V. Schreiber; Y.Z. Guang; A. Saberi; M. Masutani; N. Adachi; H. Koyama; G. De Murcia; S. Takeda H. Hochegger; D. Dejsuphong; T. Fukushima; C. Morrison; E. Sonoda; V. Schreiber; Y.Z. Guang; A. Saberi; M. Masutani; N. Adachi; H. Koyama; G. De Murcia; S. Takeda Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells EMBO Journal, 25, 6, 1305-1314 , 25, 6, 1305-1314 EMBO Journal, 25, 6, 1305-1314 2006 英語 公開
C. Guo; E. Sonoda; T.-S. Tang; J.L. Parker; A.B. Bielen; S. Takeda; H.D. Ulrich; E.C. Friedberg C. Guo; E. Sonoda; T.-S. Tang; J.L. Parker; A.B. Bielen; S. Takeda; H.D. Ulrich; E.C. Friedberg REV1 Protein Interacts with PCNA: Significance of the REV1 BRCT Domain In Vitro and In Vivo REV1 Protein Interacts with PCNA: Significance of the REV1 BRCT Domain In Vitro and In Vivo Molecular Cell, 23, 2, 265-271 , 23, 2, 265-271 Molecular Cell, 23, 2, 265-271 2006 英語 公開
E. Sonoda; H. Hochegger; A. Saberi; Y. Taniguchi; S. Takeda E. Sonoda; H. Hochegger; A. Saberi; Y. Taniguchi; S. Takeda Differential usage of non-homologous end-joining and homologous recombination in double strand break repair Differential usage of non-homologous end-joining and homologous recombination in double strand break repair DNA Repair, 5, 9-10, 1021-1029 , 5, 9-10, 1021-1029 DNA Repair, 5, 9-10, 1021-1029 2006 英語 公開
M. Yoshimura; M. Kohzaki; J. Nakamura; K. Asagoshi; E. Sonoda; E. Hou; R. Prasad; S.H. Wilson; K. Tano; A. Yasui; L. Lan; M. Seki; R.D. Wood; H. Arakawa; J.-M. Buerstedde; H. Hochegger; T. Okada; M. Hiraoka; S. Takeda M. Yoshimura; M. Kohzaki; J. Nakamura; K. Asagoshi; E. Sonoda; E. Hou; R. Prasad; S.H. Wilson; K. Tano; A. Yasui; L. Lan; M. Seki; R.D. Wood; H. Arakawa; J.-M. Buerstedde; H. Hochegger; T. Okada; M. Hiraoka; S. Takeda Vertebrate POLQ and POLβ Cooperate in Base Excision Repair of Oxidative DNA Damage Vertebrate POLQ and POLβ Cooperate in Base Excision Repair of Oxidative DNA Damage Molecular Cell, 24, 1, 115-125 , 24, 1, 115-125 Molecular Cell, 24, 1, 115-125 2006 英語 公開
A. Yoshimura; K. Nishino; J. Takezawa; S. Tada; T. Kobayashi; E. Sonoda; T. Kawamoto; S. Takeda; Y. Ishii; K. Yamada; T. Enomoto; M. Seki A. Yoshimura; K. Nishino; J. Takezawa; S. Tada; T. Kobayashi; E. Sonoda; T. Kawamoto; S. Takeda; Y. Ishii; K. Yamada; T. Enomoto; M. Seki A novel Rad18 function involved in protection of the vertebrate genome after exposure to camptothecin A novel Rad18 function involved in protection of the vertebrate genome after exposure to camptothecin DNA Repair, 5, 11, 1307-1316 , 5, 11, 1307-1316 DNA Repair, 5, 11, 1307-1316 2006 英語 公開
C. Guo; T.-S. Tang; M. Bienko; J.L. Parker; A.B. Bielen; E. Sonoda; S. Takeda; H.D. Ulrich; I. Dikic; E.C. Friedberg C. Guo; T.-S. Tang; M. Bienko; J.L. Parker; A.B. Bielen; E. Sonoda; S. Takeda; H.D. Ulrich; I. Dikic; E.C. Friedberg Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage Molecular and Cellular Biology, 26, 23, 8892-8900 , 26, 23, 8892-8900 Molecular and Cellular Biology, 26, 23, 8892-8900 2006 英語 公開
Y. Taniguchi; S. Takeda; M. Furutani-Seiki; Y. Kamei; T. Todo; T. Sasado; T. Deguchi; H. Kondoh; J. Mudde; M. Yamazoe; M. Hidaka; H. Mitani; A. Toyoda; Y. Sakaki; R.H.A. Plasterk; E. Cuppen Y. Taniguchi; S. Takeda; M. Furutani-Seiki; Y. Kamei; T. Todo; T. Sasado; T. Deguchi; H. Kondoh; J. Mudde; M. Yamazoe; M. Hidaka; H. Mitani; A. Toyoda; Y. Sakaki; R.H.A. Plasterk; E. Cuppen Generation of medaka gene knockout models by target-selected mutagenesis Generation of medaka gene knockout models by target-selected mutagenesis Genome Biology, 7, 12 , 7, 12 Genome Biology, 7, 12 2006 英語 公開
H. Hochegger; S. Takeda H. Hochegger; S. Takeda Phenotypic analysis of cellular responses to DNA damage. Phenotypic analysis of cellular responses to DNA damage. Sub-cellular biochemistry, 40, 313-325 , 40, 313-325 Sub-cellular biochemistry, 40, 313-325 2006 英語 公開
K. Nojima; H. Hochegger; A. Saberi; T. Fukushima; K. Kikuchi; M. Yoshimura; B.J. Orelli; D.K. Bishop; S. Hirano; M. Ohzeki; M. Ishiai; K. Yamamoto; M. Takata; H. Arakawa; J.-M. Buerstedde; M. Yamazoe; T. Kawamoto; K. Araki; J.A. Takahashi; N. Hashimoto; S. Takeda; E. Sonoda K. Nojima; H. Hochegger; A. Saberi; T. Fukushima; K. Kikuchi; M. Yoshimura; B.J. Orelli; D.K. Bishop; S. Hirano; M. Ohzeki; M. Ishiai; K. Yamamoto; M. Takata; H. Arakawa; J.-M. Buerstedde; M. Yamazoe; T. Kawamoto; K. Araki; J.A. Takahashi; N. Hashimoto; S. Takeda; E. Sonoda Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells Cancer Research, 65, 24, 11704-11711 , 65, 24, 11704-11711 Cancer Research, 65, 24, 11704-11711 2005/12/15 英語 公開
T. Kawamoto; K. Araki; E. Sonoda; Y.M. Yamashita; K. Harada; K. Kikuchi; C. Masutani; F. Hanaoka; K. Nozaki; N. Hashimoto; S. Takeda T. Kawamoto; K. Araki; E. Sonoda; Y.M. Yamashita; K. Harada; K. Kikuchi; C. Masutani; F. Hanaoka; K. Nozaki; N. Hashimoto; S. Takeda Dual roles for DNA polymerase η in homologous DNA recombination and translesion DNA synthesis Dual roles for DNA polymerase η in homologous DNA recombination and translesion DNA synthesis Molecular Cell, 20, 5, 793-799 , 20, 5, 793-799 Molecular Cell, 20, 5, 793-799 2005/12/09 英語 公開
S. Hirano; K. Yamamoto; M. Ishiai; M. Yamazoe; M. Seki; N. Matsushita; M. Ohzeki; Y.M. Yamashita; H. Arakawa; J.-M. Buerstedde; T. Enomoto; S. Takeda; L.H. Thompson; M. Takata S. Hirano; K. Yamamoto; M. Ishiai; M. Yamazoe; M. Seki; N. Matsushita; M. Ohzeki; Y.M. Yamashita; H. Arakawa; J.-M. Buerstedde; T. Enomoto; S. Takeda; L.H. Thompson; M. Takata Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM EMBO Journal, 24, 2, 418-427 , 24, 2, 418-427 EMBO Journal, 24, 2, 418-427 2005 英語 公開
A. Hatanaka; M. Yamazoe; J.E. Sale; M. Takata; K. Yamamoto; H. Kitao; E. Sonoda; K. Kikuchi; Y. Yonetani; S. Takeda A. Hatanaka; M. Yamazoe; J.E. Sale; M. Takata; K. Yamamoto; H. Kitao; E. Sonoda; K. Kikuchi; Y. Yonetani; S. Takeda Similar effects of Brca2 truncation and Rad51 paralog deficiency on immimoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination Similar effects of Brca2 truncation and Rad51 paralog deficiency on immimoglobulin V gene diversification in DT40 cells support an early role for Rad51 paralogs in homologous recombination Molecular and Cellular Biology, 25, 3, 1124-1134 , 25, 3, 1124-1134 Molecular and Cellular Biology, 25, 3, 1124-1134 2005 英語 公開
T. Okada; E. Sonoda; M. Yoshimura; Y. Kawano; H. Saya; M. Kohzaki; S. Takeda T. Okada; E. Sonoda; M. Yoshimura; Y. Kawano; H. Saya; M. Kohzaki; S. Takeda Multiple roles of vertebrate REV genes in DNA repair and recombination Multiple roles of vertebrate REV genes in DNA repair and recombination Molecular and Cellular Biology, 25, 14, 6103-6111 , 25, 14, 6103-6111 Molecular and Cellular Biology, 25, 14, 6103-6111 2005 英語 公開
K. Kikuchi; Y. Taniguchi; A. Hatanaka; E. Sonoda; H. Hochegger; N. Adachi; Y. Matsuzaki; H. Koyama; D.C. Van Gent; M. Jasin; S. Takeda K. Kikuchi; Y. Taniguchi; A. Hatanaka; E. Sonoda; H. Hochegger; N. Adachi; Y. Matsuzaki; H. Koyama; D.C. Van Gent; M. Jasin; S. Takeda Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends Molecular and Cellular Biology, 25, 16, 6948-6955 , 25, 16, 6948-6955 Molecular and Cellular Biology, 25, 16, 6948-6955 2005 英語 公開
Y. Yonetani; H. Hochegger; E. Sonoda; S. Shinya; H. Yoshikawa; S. Takeda; M. Yamazoe Y. Yonetani; H. Hochegger; E. Sonoda; S. Shinya; H. Yoshikawa; S. Takeda; M. Yamazoe Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage Differential and collaborative actions of Rad51 paralog proteins in cellular response to DNA damage Nucleic Acids Research, 33, 14, 4544-4552 , 33, 14, 4544-4552 Nucleic Acids Research, 33, 14, 4544-4552 2005 英語 公開
H. Seo; M. Masuoka; H. Murofushi; S. Takeda; T. Shibata; K. Ohta H. Seo; M. Masuoka; H. Murofushi; S. Takeda; T. Shibata; K. Ohta Rapid generation of specific antibodies by enhanced homologous recombination Rapid generation of specific antibodies by enhanced homologous recombination Nature Biotechnology, 23, 6, 731-735 , 23, 6, 731-735 Nature Biotechnology, 23, 6, 731-735 2005 英語 公開
M. Ishiai; M. Kimura; K. Namikoshi; M. Yamazoe; K. Yamamoto; H. Arakawa; K. Agematsu; N. Matsushita; S. Takeda; J.-M. Buerstedde; M. Takata M. Ishiai; M. Kimura; K. Namikoshi; M. Yamazoe; K. Yamamoto; H. Arakawa; K. Agematsu; N. Matsushita; S. Takeda; J.-M. Buerstedde; M. Takata DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation Molecular and Cellular Biology, 24, 24, 10733-10741 , 24, 24, 10733-10741 Molecular and Cellular Biology, 24, 24, 10733-10741 2004 英語 公開
H. Hochegger; E. Sonoda; S. Takeda H. Hochegger; E. Sonoda; S. Takeda Post-replication repair in DT40 cells: Translesion polymerases versus recombinases Post-replication repair in DT40 cells: Translesion polymerases versus recombinases BioEssays, 26, 2, 151-158 , 26, 2, 151-158 BioEssays, 26, 2, 151-158 2004 英語 公開
T. Fukao; P. Chen; J. Ren; H. Kaneko; G.X. Zhang; M. Kondo; K.-I. Yamamoto; Y. Furuichi; S. Takeda; N. Kondo; M.F. Lavin T. Fukao; P. Chen; J. Ren; H. Kaneko; G.X. Zhang; M. Kondo; K.-I. Yamamoto; Y. Furuichi; S. Takeda; N. Kondo; M.F. Lavin Disruption of the BLM gene in ATM-null DT40 cells does not exacerbate either phenotype Disruption of the BLM gene in ATM-null DT40 cells does not exacerbate either phenotype Oncogene, 23, 8, 1498-1506 , 23, 8, 1498-1506 Oncogene, 23, 8, 1498-1506 2004 英語 公開
P. Vagnarelli; C. Morrison; H. Dodson; E. Sonoda; S. Takeda; W.C. Earnshaw P. Vagnarelli; C. Morrison; H. Dodson; E. Sonoda; S. Takeda; W.C. Earnshaw Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores EMBO Reports, 5, 2, 167-171 , 5, 2, 167-171 EMBO Reports, 5, 2, 167-171 2004 英語 公開
A. Mizutani; T. Okada; S. Shibutani; E. Sonoda; H. Hochegger; C. Nishigori; Y. Miyachi; S. Takeda; M. Yamazoe A. Mizutani; T. Okada; S. Shibutani; E. Sonoda; H. Hochegger; C. Nishigori; Y. Miyachi; S. Takeda; M. Yamazoe Extensive Chromosomal Breaks Are Induced by Tamoxifen and Estrogen in DNA Repair-Deficient Cells Extensive Chromosomal Breaks Are Induced by Tamoxifen and Estrogen in DNA Repair-Deficient Cells Cancer Research, 64, 9, 3144-3147 , 64, 9, 3144-3147 Cancer Research, 64, 9, 3144-3147 2004 英語 公開
M. Yamazoe; E. Sonoda; H. Hochegger; S. Takeda M. Yamazoe; E. Sonoda; H. Hochegger; S. Takeda Reverse genetic studies of the DNA damage response in the chicken B lymphocyte line DT40 Reverse genetic studies of the DNA damage response in the chicken B lymphocyte line DT40 DNA Repair, 3, 8-9, 1175-1185 , 3, 8-9, 1175-1185 DNA Repair, 3, 8-9, 1175-1185 2004 英語 公開
H. Dodson; E. Bourke; L.J. Jeffers; P. Vagnarelli; E. Sonoda; S. Takeda; W.C. Earnshaw; A. Merdes; C. Morrison H. Dodson; E. Bourke; L.J. Jeffers; P. Vagnarelli; E. Sonoda; S. Takeda; W.C. Earnshaw; A. Merdes; C. Morrison Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM EMBO Journal, 23, 19, 3864-3873 , 23, 19, 3864-3873 EMBO Journal, 23, 19, 3864-3873 2004 英語 公開
M.S. Sasaki; M. Takata; E. Sonoda; A. Tachibana; S. Takeda M.S. Sasaki; M. Takata; E. Sonoda; A. Tachibana; S. Takeda Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks Cytogenetic and Genome Research, 104, 1-4, 28-34 , 104, 1-4, 28-34 Cytogenetic and Genome Research, 104, 1-4, 28-34 2004 英語 公開
E. Sonoda; T. Okada; G.Y. Zhao; S. Tateishi; K. Araki; M. Yamaizumi; T. Yagi; N.S. Verkaik; D.C. Van Gent; M. Takata; S. Takeda E. Sonoda; T. Okada; G.Y. Zhao; S. Tateishi; K. Araki; M. Yamaizumi; T. Yagi; N.S. Verkaik; D.C. Van Gent; M. Takata; S. Takeda Multiple roles of Rev3, the catalytic subunit of polζ in maintaining genome stability in vertebrates Multiple roles of Rev3, the catalytic subunit of polζ in maintaining genome stability in vertebrates EMBO Journal, 22, 12, 3188-3197 , 22, 12, 3188-3197 EMBO Journal, 22, 12, 3188-3197 2003 英語 公開
J. Henry-Mowatt; D. Jackson; J.-Y. Masson; P.A. Johnson; P.M. Clements; F.E. Benson; L.H. Thompson; S. Takeda; S.C. West; K.W. Caldecott J. Henry-Mowatt; D. Jackson; J.-Y. Masson; P.A. Johnson; P.M. Clements; F.E. Benson; L.H. Thompson; S. Takeda; S.C. West; K.W. Caldecott XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes Molecular Cell, 11, 4, 1109-1117 , 11, 4, 1109-1117 Molecular Cell, 11, 4, 1109-1117 2003 英語 公開
D.S. Yu; E. Sonoda; S. Takeda; C.L.H. Huang; L. Pellegrini; T.L. Blundell; A.R. Venkitaraman D.S. Yu; E. Sonoda; S. Takeda; C.L.H. Huang; L. Pellegrini; T.L. Blundell; A.R. Venkitaraman Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2 Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2 Molecular Cell, 12, 4, 1029-1041 , 12, 4, 1029-1041 Molecular Cell, 12, 4, 1029-1041 2003 英語 公開
M. Hashimoto; S. Rao; O. Tokuno; K.-I. Yamamoto; M. Takata; S. Takeda; H. Utsumi M. Hashimoto; S. Rao; O. Tokuno; K.-I. Yamamoto; M. Takata; S. Takeda; H. Utsumi DNA-PK: The major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway DNA-PK: The major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway Journal of Radiation Research, 44, 2, 151-159 , 44, 2, 151-159 Journal of Radiation Research, 44, 2, 151-159 2003 英語 公開
C. Morrison; P. Vagnarelli; E. Sonoda; S. Takeda; W.C. Earnshaw C. Morrison; P. Vagnarelli; E. Sonoda; S. Takeda; W.C. Earnshaw Sister chromatid cohesion and genome stability in vertebrate cells Sister chromatid cohesion and genome stability in vertebrate cells Biochemical Society Transactions, 31, 1, 263-265 , 31, 1, 263-265 Biochemical Society Transactions, 31, 1, 263-265 2003 英語 公開
H. Tauchi; J. Kobayashi; K.-I. Morishima; D.C. Van Gent; T. Shiraishi; T. Shiraishi; N.S. Verkaik; D. VanHeems; E. Ito; A. Nakamura; E. Sonoda; M. Takata; S. Takeda; S. Matsuura; K. Komatsu H. Tauchi; J. Kobayashi; K.-I. Morishima; D.C. Van Gent; T. Shiraishi; T. Shiraishi; N.S. Verkaik; D. VanHeems; E. Ito; A. Nakamura; E. Sonoda; M. Takata; S. Takeda; S. Matsuura; K. Komatsu Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells Nature, 420, 6911, 93-98 , 420, 6911, 93-98 Nature, 420, 6911, 93-98 2002/11/07 英語 公開
T. Tanaka; F. Hosoi; Y. Yamaguchi-Iwai; H. Nakamura; H. Masutani; S. Ueda; A. Nishiyama; S. Takeda; H. Wada; G. Spyrou; J. Yodoi T. Tanaka; F. Hosoi; Y. Yamaguchi-Iwai; H. Nakamura; H. Masutani; S. Ueda; A. Nishiyama; S. Takeda; H. Wada; G. Spyrou; J. Yodoi Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis EMBO Journal, 21, 7, 1695-1703 , 21, 7, 1695-1703 EMBO Journal, 21, 7, 1695-1703 2002/04/02 英語 公開
C. Wei; R. Skopp; M. Takata; S. Takeda; C.M. Price C. Wei; R. Skopp; M. Takata; S. Takeda; C.M. Price Effects of double-strand break repair proteins on vertebrate telomere structure Effects of double-strand break repair proteins on vertebrate telomere structure Nucleic Acids Research, 30, 13, 2862-2870 , 30, 13, 2862-2870 Nucleic Acids Research, 30, 13, 2862-2870 2002 英語 公開
S.J. Cumbers; G.T. Williams; S.L. Davies; R.L. Grenfell; S. Takeda; F.D. Batista; J.E. Sale; M.S. Neuberger S.J. Cumbers; G.T. Williams; S.L. Davies; R.L. Grenfell; S. Takeda; F.D. Batista; J.E. Sale; M.S. Neuberger Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines Nature Biotechnology, 20, 11, 1129-1134 , 20, 11, 1129-1134 Nature Biotechnology, 20, 11, 1129-1134 2002 英語 公開
N.G.J. Jaspers; A. Raams; M.J. Kelner; J.M.Y. Ng; Y.M. Yamashita; S. Takeda; T.C. McMorris; J.H.J. Hoeijmakers N.G.J. Jaspers; A. Raams; M.J. Kelner; J.M.Y. Ng; Y.M. Yamashita; S. Takeda; T.C. McMorris; J.H.J. Hoeijmakers Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways DNA Repair, 1, 12, 1027-1038 , 1, 12, 1027-1038 DNA Repair, 1, 12, 1027-1038 2002 英語 公開
M. Takata; S. Tachiiri; A. Fujimori; L.H. Thompson; Y. Miki; M. Hiraoka; S. Takeda; M. Yamazoe M. Takata; S. Tachiiri; A. Fujimori; L.H. Thompson; Y. Miki; M. Hiraoka; S. Takeda; M. Yamazoe Conserved domains in the chicken homologue of BRCA2 Conserved domains in the chicken homologue of BRCA2 Oncogene, 21, 7, 1130-1134 , 21, 7, 1130-1134 Oncogene, 21, 7, 1130-1134 2002 英語 公開
T. Okada; E. Sonoda; Y.M. Yamashita; S. Koyoshi; S. Tateishi; M. Yamaizumi; M. Takata; O. Ogawa; S. Takeda T. Okada; E. Sonoda; Y.M. Yamashita; S. Koyoshi; S. Tateishi; M. Yamaizumi; M. Takata; O. Ogawa; S. Takeda Involvement of vertebrate Polκ in Rad18-independent postreplication repair of UV damage Involvement of vertebrate Polκ in Rad18-independent postreplication repair of UV damage Journal of Biological Chemistry, 277, 50, 48690-48695 , 277, 50, 48690-48695 Journal of Biological Chemistry, 277, 50, 48690-48695 2002 英語 公開
Y.M. Yamashita; T. Okada; T. Matsusaka; E. Sonoda; G.Y. Zhao; K. Araki; S. Tateishi; M. Yamaizumi; S. Takeda Y.M. Yamashita; T. Okada; T. Matsusaka; E. Sonoda; G.Y. Zhao; K. Araki; S. Tateishi; M. Yamaizumi; S. Takeda RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells RAD18 and RAD54 cooperatively contribute to maintenance of genomic stability in vertebrate cells EMBO Journal, 21, 20, 5558-5566 , 21, 20, 5558-5566 EMBO Journal, 21, 20, 5558-5566 2002 英語 公開
O. Imamura; K. Fujita; C. Itoh; S. Takeda; Y. Furuichi; T. Matsumoto O. Imamura; K. Fujita; C. Itoh; S. Takeda; Y. Furuichi; T. Matsumoto Werner and Bloom helicases are involved in DNA repair in a complementary fashion Werner and Bloom helicases are involved in DNA repair in a complementary fashion Oncogene, 21, 6, 954-963 , 21, 6, 954-963 Oncogene, 21, 6, 954-963 2002 英語 公開
H. Utsumi; K. Tano; M. Takata; S. Takeda; M.M. Elkind H. Utsumi; K. Tano; M. Takata; S. Takeda; M.M. Elkind Requirement for repair of DNA double-strand breaks by homologous recombination in split-dose recovery Requirement for repair of DNA double-strand breaks by homologous recombination in split-dose recovery Radiation Research, 155, 5, 680-686 , 155, 5, 680-686 Radiation Research, 155, 5, 680-686 2001 英語 公開
M. Takata; M.S. Sasaki; S. Tachiiri; T. Fukushima; E. Sonoda; D. Schild; L.H. Thompson; S. Takeda M. Takata; M.S. Sasaki; S. Tachiiri; T. Fukushima; E. Sonoda; D. Schild; L.H. Thompson; S. Takeda Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs Molecular and Cellular Biology, 21, 8, 2858-2866 , 21, 8, 2858-2866 Molecular and Cellular Biology, 21, 8, 2858-2866 2001 英語 公開
J. Kirberg; H. von Boehmer; T. Brocker; H.R. Rodewald; S. Takeda J. Kirberg; H. von Boehmer; T. Brocker; H.R. Rodewald; S. Takeda Class II essential for CD4 survival. Class II essential for CD4 survival. Nature immunology, 2, 2, 136-137 , 2, 2, 136-137 Nature immunology, 2, 2, 136-137 2001 英語 公開
O. Imamura; K. Fujita; A. Shimamoto; H. Tanabe; S. Takeda; Y. Furuichi; T. Matsumoto O. Imamura; K. Fujita; A. Shimamoto; H. Tanabe; S. Takeda; Y. Furuichi; T. Matsumoto Bloom helicase is involved in DNA surveillance in early s phase in vertebrate cells Bloom helicase is involved in DNA surveillance in early s phase in vertebrate cells Oncogene, 20, 10, 1143-1151 , 20, 10, 1143-1151 Oncogene, 20, 10, 1143-1151 2001 英語 公開
T. Sudo; Y. Ota; S. Kotani; M. Nakao; Y. Takami; S. Takeda; H. Saya T. Sudo; Y. Ota; S. Kotani; M. Nakao; Y. Takami; S. Takeda; H. Saya Activation of Cdh1-dependent APC is required for G<sub>1</sub> cell cycle arrest and DNA damage-induced G<sub>2</sub> checkpoint in vertebrate cells Activation of Cdh1-dependent APC is required for G<sub>1</sub> cell cycle arrest and DNA damage-induced G<sub>2</sub> checkpoint in vertebrate cells EMBO Journal, 20, 22, 6499-6508 , 20, 22, 6499-6508 EMBO Journal, 20, 22, 6499-6508 2001 英語 公開
H. Wang; Z.-C. Zeng; T.-A. Bui; E. Sonoda; M. Takata; S. Takeda; G. Iliakis H. Wang; Z.-C. Zeng; T.-A. Bui; E. Sonoda; M. Takata; S. Takeda; G. Iliakis Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group Oncogene, 20, 18, 2212-2224 , 20, 18, 2212-2224 Oncogene, 20, 18, 2212-2224 2001 英語 公開
E. Sonoda; C. Morrison; Y.M. Yamashita; M. Takata; S. Takeda E. Sonoda; C. Morrison; Y.M. Yamashita; M. Takata; S. Takeda Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40 Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40 Philosophical Transactions of the Royal Society B: Biological Sciences, 355, 1405, 111-117 , 355, 1405, 111-117 Philosophical Transactions of the Royal Society B: Biological Sciences, 355, 1405, 111-117 2001 英語 公開
J.E. Sale; D.M. Calandrini; M. Takata; S. Takeda; M.S. Neuberger J.E. Sale; D.M. Calandrini; M. Takata; S. Takeda; M.S. Neuberger Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation [4] Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation [4] Nature, 412, 6850, 921-926 , 412, 6850, 921-926 Nature, 412, 6850, 921-926 2001 英語 公開
T. Fukushima; M. Takata; C. Morrison; R. Araki; A. Fujimori; M. Abe; K. Tatsumi; M. Jasin; P.K. Dhar; E. Sonoda; T. Chiba; S. Takeda T. Fukushima; M. Takata; C. Morrison; R. Araki; A. Fujimori; M. Abe; K. Tatsumi; M. Jasin; P.K. Dhar; E. Sonoda; T. Chiba; S. Takeda Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S-G<sub>2</sub> Phase DNA Double-strand Break Repair Genetic Analysis of the DNA-dependent Protein Kinase Reveals an Inhibitory Role of Ku in Late S-G<sub>2</sub> Phase DNA Double-strand Break Repair Journal of Biological Chemistry, 276, 48, 44413-44418 , 276, 48, 44413-44418 Journal of Biological Chemistry, 276, 48, 44413-44418 2001 英語 公開
A. Fujimori; S. Tachiiri; E. Sonoda; L.H. Thompson; P.K. Dhar; M. Hiraoka; S. Takeda; Y. Zhang; M. Reth; M. Takata A. Fujimori; S. Tachiiri; E. Sonoda; L.H. Thompson; P.K. Dhar; M. Hiraoka; S. Takeda; Y. Zhang; M. Reth; M. Takata Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells EMBO Journal, 20, 19, 5513-5520 , 20, 19, 5513-5520 EMBO Journal, 20, 19, 5513-5520 2001 英語 公開
E. Sonoda; T. Matsusaka; C. Morrison; P. Vagnarelli; O. Hoshi; T. Ushiki; K. Nojima; T. Fukagawa; I.C. Waizenegger; J.-M. Peters; W.C. Earnshaw; S. Takeda E. Sonoda; T. Matsusaka; C. Morrison; P. Vagnarelli; O. Hoshi; T. Ushiki; K. Nojima; T. Fukagawa; I.C. Waizenegger; J.-M. Peters; W.C. Earnshaw; S. Takeda Scc1/Rad21/Mcd1 Is Required for Sister Chromatid Cohesion and Kinetochore Function in Vertebrate Cells Scc1/Rad21/Mcd1 Is Required for Sister Chromatid Cohesion and Kinetochore Function in Vertebrate Cells Developmental Cell, 1, 6, 759-770 , 1, 6, 759-770 Developmental Cell, 1, 6, 759-770 2001 英語 公開
E. Sonoda; M. Takata; Y.M. Yamashita; S. Takeda E. Sonoda; M. Takata; Y.M. Yamashita; S. Takeda Homologous DNA recombination is essential for the proliferation of vertebrate cells Homologous DNA recombination is essential for the proliferation of vertebrate cells Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 46, 8 Suppl, 1046-1054 , 46, 8 Suppl, 1046-1054 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 46, 8 Suppl, 1046-1054 2001 英語 公開
P.K. Dhar; E. Sonoda; A. Fujimori; Y.M. Yamashita; S. Takeda P.K. Dhar; E. Sonoda; A. Fujimori; Y.M. Yamashita; S. Takeda DNA repair studies: Experimental evidence in support of chicken DT40 cell line as a unique model DNA repair studies: Experimental evidence in support of chicken DT40 cell line as a unique model Journal of Environmental Pathology, Toxicology and Oncology, 20, 4, 273-283 , 20, 4, 273-283 Journal of Environmental Pathology, Toxicology and Oncology, 20, 4, 273-283 2001 英語 公開
M. Takata; M.S. Sasaki; E. Sonoda; T. Fukushima; C. Morrison; J.S. Albala; S.M.A. Swagemakers; R. Kanaar; L.H. Thompson; S. Takeda M. Takata; M.S. Sasaki; E. Sonoda; T. Fukushima; C. Morrison; J.S. Albala; S.M.A. Swagemakers; R. Kanaar; L.H. Thompson; S. Takeda The Rad51 paralog Rad51B promotes homologous recombinational repair The Rad51 paralog Rad51B promotes homologous recombinational repair Molecular and Cellular Biology, 20, 17, 6476-6482 , 20, 17, 6476-6482 Molecular and Cellular Biology, 20, 17, 6476-6482 2000 英語 公開
C. Morrison; E. Sonoda; N. Takao; A. Shinohara; K.-I. Yamamoto; S. Takeda C. Morrison; E. Sonoda; N. Takao; A. Shinohara; K.-I. Yamamoto; S. Takeda The controlling role of ATM in homologous recombinational repair of DNA damage The controlling role of ATM in homologous recombinational repair of DNA damage EMBO Journal, 19, 3, 463-471 , 19, 3, 463-471 EMBO Journal, 19, 3, 463-471 2000 英語 公開
C. Morrison; S. Takeda C. Morrison; S. Takeda Genetic analysis of homologous DNA recombination in vertebrate somatic cells Genetic analysis of homologous DNA recombination in vertebrate somatic cells International Journal of Biochemistry and Cell Biology, 32, 8, 817-831 , 32, 8, 817-831 International Journal of Biochemistry and Cell Biology, 32, 8, 817-831 2000 英語 公開
W. Wang; M. Seki; Y. Narita; E. Sonoda; S. Takeda; K. Yamada; T. Masuko; T. Katada; T. Enomoto W. Wang; M. Seki; Y. Narita; E. Sonoda; S. Takeda; K. Yamada; T. Masuko; T. Katada; T. Enomoto Possible association of BLM in decreasing DNA double strand breaks during DNA replication Possible association of BLM in decreasing DNA double strand breaks during DNA replication EMBO Journal, 19, 13, 3428-3435 , 19, 13, 3428-3435 EMBO Journal, 19, 13, 3428-3435 2000 英語 公開
Y. Yamaguchi-Iwai; E. Sonoda; M.S. Sasaki; C. Morrison; T. Haraguchi; Y. Hiraoka; Y.M. Yamashita; T. Yagi; M. Takata; C. Price; N. Kakazu; S. Takeda Y. Yamaguchi-Iwai; E. Sonoda; M.S. Sasaki; C. Morrison; T. Haraguchi; Y. Hiraoka; Y.M. Yamashita; T. Yagi; M. Takata; C. Price; N. Kakazu; S. Takeda Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells EMBO Journal, 18, 23, 6619-6629 , 18, 23, 6619-6629 EMBO Journal, 18, 23, 6619-6629 1999 英語 公開
N. Takao; H. Kato; R. Mori; C. Morrison; E. Sonada; X. Sun; H. Shimizu; K. Yoshioka; S. Takeda; K.-I. Yamamoto N. Takao; H. Kato; R. Mori; C. Morrison; E. Sonada; X. Sun; H. Shimizu; K. Yoshioka; S. Takeda; K.-I. Yamamoto Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation Oncogene, 18, 50, 7002-7009 , 18, 50, 7002-7009 Oncogene, 18, 50, 7002-7009 1999 英語 公開
C. Morrison; A. Shinohara; E. Sonoda; Y. Yamaguchi-Iwai; M. Takata; R.R. Weichselbaum; S. Takeda C. Morrison; A. Shinohara; E. Sonoda; Y. Yamaguchi-Iwai; M. Takata; R.R. Weichselbaum; S. Takeda The essential functions of human Rad51 are independent of ATP hydrolysis The essential functions of human Rad51 are independent of ATP hydrolysis Molecular and Cellular Biology, 19, 10, 6891-6897 , 19, 10, 6891-6897 Molecular and Cellular Biology, 19, 10, 6891-6897 1999 英語 公開
E. Sonoda; M.S. Sasaki; C. Morrison; Y. Yamaguchi-Iwai; M. Takata; S. Takeda E. Sonoda; M.S. Sasaki; C. Morrison; Y. Yamaguchi-Iwai; M. Takata; S. Takeda Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells Molecular and Cellular Biology, 19, 7, 5166-5169 , 19, 7, 5166-5169 Molecular and Cellular Biology, 19, 7, 5166-5169 1999 英語 公開
M. Tanabe; Y. Kawazoe; S. Takeda; R.I. Morimoto; K. Nagata; A. Nakai M. Tanabe; Y. Kawazoe; S. Takeda; R.I. Morimoto; K. Nagata; A. Nakai Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance EMBO Journal, 17, 6, 1750-1758 , 17, 6, 1750-1758 EMBO Journal, 17, 6, 1750-1758 1998/03/16 英語 公開
E. Sonoda; M.S. Sasaki; J.-M. Buerstedde; O. Bezzubova; A. Shinohara; H. Ogawa; M. Takata; Y. Yamaguchi-Iwai; S. Takeda E. Sonoda; M.S. Sasaki; J.-M. Buerstedde; O. Bezzubova; A. Shinohara; H. Ogawa; M. Takata; Y. Yamaguchi-Iwai; S. Takeda Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death EMBO Journal, 17, 2, 598-608 , 17, 2, 598-608 EMBO Journal, 17, 2, 598-608 1998 英語 公開
Y. Kuroiwa; T. Shinohara; T. Notsu; K. Tomizuka; H. Yoshida; S.-I. Takeda; M. Oshimura; I. Ishida Y. Kuroiwa; T. Shinohara; T. Notsu; K. Tomizuka; H. Yoshida; S.-I. Takeda; M. Oshimura; I. Ishida Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells Nucleic Acids Research, 26, 14, 3447-3448 , 26, 14, 3447-3448 Nucleic Acids Research, 26, 14, 3447-3448 1998 英語 公開
M. Takata; M.S. Sasaki; E. Sonoda; C. Morrison; M. Hashimoto; H. Utsumi; Y. Yamaguchi-Iwai; A. Shinohara; S. Takeda M. Takata; M.S. Sasaki; E. Sonoda; C. Morrison; M. Hashimoto; H. Utsumi; Y. Yamaguchi-Iwai; A. Shinohara; S. Takeda Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells EMBO Journal, 17, 18, 5497-5508 , 17, 18, 5497-5508 EMBO Journal, 17, 18, 5497-5508 1998 英語 公開
Y. Yamaguchi-Iwai; E. Sonoda; J.-M. Buerstedde; O. Bezzubova; C. Morrison; M. Takata; A. Shinohara; S. Takeda Y. Yamaguchi-Iwai; E. Sonoda; J.-M. Buerstedde; O. Bezzubova; C. Morrison; M. Takata; A. Shinohara; S. Takeda Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52 Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52 Molecular and Cellular Biology, 18, 11, 6430-6435 , 18, 11, 6430-6435 Molecular and Cellular Biology, 18, 11, 6430-6435 1998 英語 公開
S. Takeda; E. Sonoda; M. Takata; C. Morrison; S. Tachiiri; Y. Yamaguchi-Iwai S. Takeda; E. Sonoda; M. Takata; C. Morrison; S. Tachiiri; Y. Yamaguchi-Iwai Recombinational repair is essential for the maintenance of chromosomal integrity in cycling vertebrate cells Recombinational repair is essential for the maintenance of chromosomal integrity in cycling vertebrate cells Experimental Hematology, 26, 8, 738- , 26, 8, 738- Experimental Hematology, 26, 8, 738- 1998 英語 公開
O. Bezzubova; A. Silbergleit; Y. Yamaguchi-Iwai; S. Takeda; J.-M. Buerstedde O. Bezzubova; A. Silbergleit; Y. Yamaguchi-Iwai; S. Takeda; J.-M. Buerstedde Reduced X-ray resistance and homologous recombination frequencies in a RAD54(-/-) mutant of the chicken DT40 cell line Reduced X-ray resistance and homologous recombination frequencies in a RAD54(-/-) mutant of the chicken DT40 cell line Cell, 89, 2, 185-193 , 89, 2, 185-193 Cell, 89, 2, 185-193 1997 英語 公開
T. Shimizu; S. Takeda T. Shimizu; S. Takeda CD8 T cells from major histocompatibility complex class II-deficient mice respond vigorously to class II molecules in a primary mixed lymphocyte reaction CD8 T cells from major histocompatibility complex class II-deficient mice respond vigorously to class II molecules in a primary mixed lymphocyte reaction European Journal of Immunology, 27, 2, 500-508 , 27, 2, 500-508 European Journal of Immunology, 27, 2, 500-508 1997 英語 公開
Y. Takami; S. Takeda; T. Nakayama Y. Takami; S. Takeda; T. Nakayama An approximately half set of histone genes is enough for cell proliferation and a lack of several histone variants causes protein pattern changes in the DT40 chicken B cell line An approximately half set of histone genes is enough for cell proliferation and a lack of several histone variants causes protein pattern changes in the DT40 chicken B cell line Journal of Molecular Biology, 265, 4, 394-408 , 265, 4, 394-408 Journal of Molecular Biology, 265, 4, 394-408 1997 英語 公開
S. Takeda; T. Shimizu; H.-R. Rodewald S. Takeda; T. Shimizu; H.-R. Rodewald Interactions between c-kit and stem cell factor are not required for B- cell development in vivo Interactions between c-kit and stem cell factor are not required for B- cell development in vivo Blood, 89, 2, 518-525 , 89, 2, 518-525 Blood, 89, 2, 518-525 1997 英語 公開
H. Arakawa; S. Takeda H. Arakawa; S. Takeda Early expression of Ig μ chain from a transgene significantly reduces the duration of the pro-B stage but does not affect the small pre-B stage Early expression of Ig μ chain from a transgene significantly reduces the duration of the pro-B stage but does not affect the small pre-B stage International Immunology, 8, 8, 1319-1328 , 8, 8, 1319-1328 International Immunology, 8, 8, 1319-1328 1996 英語 公開
H. Arakawa; T. Shimizu; S. Takeda H. Arakawa; T. Shimizu; S. Takeda Re-evaluation of the probabilities for productive rearrangements on the κ and λ loci Re-evaluation of the probabilities for productive rearrangements on the κ and λ loci International Immunology, 8, 1, 91-99 , 8, 1, 91-99 International Immunology, 8, 1, 91-99 1996 英語 公開
S. Takeda; H.-R. Rodewald; H. Arakawa; H. Bluethmann; T. Shimizu S. Takeda; H.-R. Rodewald; H. Arakawa; H. Bluethmann; T. Shimizu MHC class II molecules are not required for survival of newly generated CD4<sup>+</sup> T cells, but affect their long-term life span MHC class II molecules are not required for survival of newly generated CD4<sup>+</sup> T cells, but affect their long-term life span Immunity, 5, 3, 217-228 , 5, 3, 217-228 Immunity, 5, 3, 217-228 1996 英語 公開
H.-R. Rodewald; K. Kretzschmar; W. Swat; S. Takeda H.-R. Rodewald; K. Kretzschmar; W. Swat; S. Takeda Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo Immunity, 3, 3, 313-319 , 3, 3, 313-319 Immunity, 3, 3, 313-319 1995 英語 公開
Y. Takami; S. Takeda; T. Nakayama Y. Takami; S. Takeda; T. Nakayama Targeted disruption of H2B-V encoding a particular H2B histone variant causes changes in protein patterns on two-dimensional polyacrylamide gel electrophoresis in the DT40 chicken B cell line Targeted disruption of H2B-V encoding a particular H2B histone variant causes changes in protein patterns on two-dimensional polyacrylamide gel electrophoresis in the DT40 chicken B cell line Journal of Biological Chemistry, 270, 51, 30664-30670 , 270, 51, 30664-30670 Journal of Biological Chemistry, 270, 51, 30664-30670 1995 英語 公開
H.-R. Rodewald; K. Kretzschmar; S. Takeda; C. Hohl; M. Dessing H.-R. Rodewald; K. Kretzschmar; S. Takeda; C. Hohl; M. Dessing Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization EMBO Journal, 13, 18, 4229-4240 , 13, 18, 4229-4240 EMBO Journal, 13, 18, 4229-4240 1994 英語 公開
S. Takeda; Y.-R. Zou; H. Bluethmann; D. Kitamura; U. Muller; K. Rajewsky S. Takeda; Y.-R. Zou; H. Bluethmann; D. Kitamura; U. Muller; K. Rajewsky Deletion of the immunoglobulin κ chain intron enhancer abolishes κ chain gene rearrangement in cis but not λ chain gene rearrangement in trans Deletion of the immunoglobulin κ chain intron enhancer abolishes κ chain gene rearrangement in cis but not λ chain gene rearrangement in trans EMBO Journal, 12, 6, 2329-2336 , 12, 6, 2329-2336 EMBO Journal, 12, 6, 2329-2336 1993 英語 公開
Y.-R. Zou; S. Takeda; K. Rajewsky Y.-R. Zou; S. Takeda; K. Rajewsky Gene targeting in the Igχ locus: Efficient generation of λ chain-expressing B cells, independent of gene rearrangements in Igχ Gene targeting in the Igχ locus: Efficient generation of λ chain-expressing B cells, independent of gene rearrangements in Igχ EMBO Journal, 12, 3, 811-820 , 12, 3, 811-820 EMBO Journal, 12, 3, 811-820 1993 英語 公開
J.-M. Buerstedde; S. Takeda J.-M. Buerstedde; S. Takeda Increased ratio of targeted to random integration after transfection of chicken B cell lines Increased ratio of targeted to random integration after transfection of chicken B cell lines Cell, 67, 1, 179-188 , 67, 1, 179-188 Cell, 67, 1, 179-188 1991 英語 公開
Y. Takemoto; T. Miki; J. Nakura; K. Nishikawa; K. Kamino; S. Takeda; K. Kuzu; M. Osame; M. Nakagawa; I. Higuchi; T. Yamada; T. Takayanagi; S. Matsubara; K. Saita; S.-i. Takai; T. Honjo; T. Ogihara Y. Takemoto; T. Miki; J. Nakura; K. Nishikawa; K. Kamino; S. Takeda; K. Kuzu; M. Osame; M. Nakagawa; I. Higuchi; T. Yamada; T. Takayanagi; S. Matsubara; K. Saita; S.-i. Takai; T. Honjo; T. Ogihara Preclinical detection in Japanese families with myotonic dystrophy using polymorphic DNA markers Preclinical detection in Japanese families with myotonic dystrophy using polymorphic DNA markers The Japanese Journal of Human Genetics, 34, 3, 189-194 , 34, 3, 189-194 The Japanese Journal of Human Genetics, 34, 3, 189-194 1989 英語 公開
J. Fujita; H. Nakayama; H. Onoue; Y. Kanakura; T. Nakano; H. Asai; S.-I. Takeda; T. Honjo; Y. Kitamura J. Fujita; H. Nakayama; H. Onoue; Y. Kanakura; T. Nakano; H. Asai; S.-I. Takeda; T. Honjo; Y. Kitamura Fibroblast-dependent growth of mouse mast cells in vitro: Duplication of mast cell depletion in mutant mice of W/W(v) genotype Fibroblast-dependent growth of mouse mast cells in vitro: Duplication of mast cell depletion in mutant mice of W/W(v) genotype Journal of Cellular Physiology, 134, 1, 78-84 , 134, 1, 78-84 Journal of Cellular Physiology, 134, 1, 78-84 1988/01 英語 公開
S.-I. Takeda; Y. Hamaguchi; S.Q. Zong; K. Kuze; T. Honjo; M. Ishimoto; T. Nakano; Y. Kitamura S.-I. Takeda; Y. Hamaguchi; S.Q. Zong; K. Kuze; T. Honjo; M. Ishimoto; T. Nakano; Y. Kitamura Introduction and expression of the interleukin 2 receptor (Tac) gene in hematopoietic stem cells with retrovirus vectors Introduction and expression of the interleukin 2 receptor (Tac) gene in hematopoietic stem cells with retrovirus vectors Growth Factors, 1, 1, 59-66 , 1, 1, 59-66 Growth Factors, 1, 1, 59-66 1988 英語 公開
S. Takeda; T. Naito; K. Hama; T. Noma; T. Honjo S. Takeda; T. Naito; K. Hama; T. Noma; T. Honjo Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences Nature, 314, 6010, 452-454 , 314, 6010, 452-454 Nature, 314, 6010, 452-454 1985 英語 公開
A. Shimuzu; S. Kondo; S.-I. Takeda; J. Yodoi; N. Ishida; H. Sabe; H. Osawa; T. Diamantstein; T. Nikaido; T. Honjo A. Shimuzu; S. Kondo; S.-I. Takeda; J. Yodoi; N. Ishida; H. Sabe; H. Osawa; T. Diamantstein; T. Nikaido; T. Honjo Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence Nucleic Acids Research, 13, 5, 1505-1516 , 13, 5, 1505-1516 Nucleic Acids Research, 13, 5, 1505-1516 1985 英語 公開
N. Ishida; T. Nikaido; S. Kondo; S. Takeda; A. Shimizu; T. Honjo N. Ishida; T. Nikaido; S. Kondo; S. Takeda; A. Shimizu; T. Honjo II-2 receptor genes II-2 receptor genes Nippon rinsho. Japanese journal of clinical medicine, 43, 6, 1267-1275 , 43, 6, 1267-1275 Nippon rinsho. Japanese journal of clinical medicine, 43, 6, 1267-1275 1985 英語 公開

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細野嘉史,関政幸,阿部拓也,石合正道,武田俊一,石井裕,高田穣,榎本武美 細野嘉史,関政幸,阿部拓也,石合正道,武田俊一,石井裕,高田穣,榎本武美 “RecQLS ヘリガーゼのDNA クロスリンク修復における役割” “RecQLS ヘリガーゼのDNA クロスリンク修復における役割” 第35回日本分子生物学会年会 2012年12月 第35回日本分子生物学会年会 2012年12月 2012 日本語 公開
細野嘉史, 阿部卓也,石合正道,多田周右,武田俊一, 高田穣, 関政幸,榎本武美 細野嘉史, 阿部卓也,石合正道,多田周右,武田俊一, 高田穣, 関政幸,榎本武美 「DNA ヘリカーゼRECQL5 のDNA 組換え・修復における機能の解析」 「DNA ヘリカーゼRECQL5 のDNA 組換え・修復における機能の解析」 第33 回日本分子生物学会年会 2010 年12 月 第33 回日本分子生物学会年会 2010 年12 月 2010 日本語 公開
北尾洋之,ナンタインドラジッド,木野村愛子,山添光芳,シュミットマイケル,武田俊一,吉永敬士, 前原喜彦,高田穣 北尾洋之,ナンタインドラジッド,木野村愛子,山添光芳,シュミットマイケル,武田俊一,吉永敬士, 前原喜彦,高田穣 「ヘリカーゼ欠損により生じるゲノム不安定性表現型」 「ヘリカーゼ欠損により生じるゲノム不安定性表現型」 第67 回日本癌学会学術総会 2008 年10 月 名古屋市 第67 回日本癌学会学術総会 2008 年10 月 名古屋市 2008 日本語 公開
田野恵三,Paul Chastain,園田英一朗,永田憲司,足立典隆,小山秀機,武田俊一,渡邉正己,中村純 田野恵三,Paul Chastain,園田英一朗,永田憲司,足立典隆,小山秀機,武田俊一,渡邉正己,中村純 Fen-1欠損細胞における酸化塩基損傷修復過程の単鎖切断修復能および脱塩基サイトの修復能とカスペース依存的な細胞死について Fen-1欠損細胞における酸化塩基損傷修復過程の単鎖切断修復能および脱塩基サイトの修復能とカスペース依存的な細胞死について 第28回日本分子生物学会年会 第28回日本分子生物学会年会 2005 日本語 公開
K.N. Yamamoto; S. Kobayashi; M. Tsuda; H. Kurumizaka; M. Takata; K. Kono; J. Jiricny; S. Takeda; K. Hirota K.N. Yamamoto; S. Kobayashi; M. Tsuda; H. Kurumizaka; M. Takata; K. Kono; J. Jiricny; S. Takeda; K. Hirota Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway Proceedings of the National Academy of Sciences of the United States of America, 108, 16, 6492-6496 , 108, 16, 6492-6496 Proceedings of the National Academy of Sciences of the United States of America, 108, 16, 6492-6496 2011/04/19 英語 公開
K. Yoshikiyo; K. Kratz; K. Hirota; K. Nishihara; M. Takata; H. Kurumizaka; S. Horimoto; S. Takeda; J. Jiricny K. Yoshikiyo; K. Kratz; K. Hirota; K. Nishihara; M. Takata; H. Kurumizaka; S. Horimoto; S. Takeda; J. Jiricny KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents Proceedings of the National Academy of Sciences of the United States of America, 107, 50, 21553-21557 , 107, 50, 21553-21557 Proceedings of the National Academy of Sciences of the United States of America, 107, 50, 21553-21557 2010/12/14 英語 公開
橋本秀春,園田英一朗,高見恭成,中山健男,武田俊一,置貝洋一 橋本秀春,園田英一朗,高見恭成,中山健男,武田俊一,置貝洋一 Linker Histone HI is involved in Homologous Recombination repair pathway Linker Histone HI is involved in Homologous Recombination repair pathway 日本分子生物学会2006 フォーラム、 名古屋、2 0 0 6 年12 月5-7 日 日本分子生物学会2006 フォーラム、 名古屋、2 0 0 6 年12 月5-7 日 2006 英語 公開
Shunichi Takeda, M. D. Ph.D Shunichi Takeda, M. D. Ph.D Reverse genetic analysis of DNA damage response in the chicken B lymphocyte line DT40 Reverse genetic analysis of DNA damage response in the chicken B lymphocyte line DT40 第1回京都大学/MD アンダーソン癌センター国際ワークショップ:DNA repair and the translational research for radiotherapy (平成17 年1 月28 日、ヒューストン) 第1回京都大学/MD アンダーソン癌センター国際ワークショップ:DNA repair and the translational research for radiotherapy (平成17 年1 月28 日、ヒューストン) 2005 英語 公開
H. Kurumizaka; S. Ikawa; M. Nakada; K. Eda; W. Kagawa; M. Takata; S. Takeda; S. Yokoyama; T. Shibata H. Kurumizaka; S. Ikawa; M. Nakada; K. Eda; W. Kagawa; M. Takata; S. Takeda; S. Yokoyama; T. Shibata Homologous-pairing activity of the human DNA-repair proteins Xrcc3·Rad51C Homologous-pairing activity of the human DNA-repair proteins Xrcc3·Rad51C Proceedings of the National Academy of Sciences of the United States of America, 98, 10, 5538-5543 , 98, 10, 5538-5543 Proceedings of the National Academy of Sciences of the United States of America, 98, 10, 5538-5543 2001 英語 公開
N. Adachi; T. Ishino; Y. Ishii; S. Takeda; H. Koyama N. Adachi; T. Ishino; Y. Ishii; S. Takeda; H. Koyama DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair Proceedings of the National Academy of Sciences of the United States of America, 98, 21, 12109-12113 , 98, 21, 12109-12113 Proceedings of the National Academy of Sciences of the United States of America, 98, 21, 12109-12113 2001 英語 公開
E. Sonoda; M. Takata; Y.M. Yamashita; C. Morrison; S. Takeda E. Sonoda; M. Takata; Y.M. Yamashita; C. Morrison; S. Takeda Homologous DNA recombination in vertebrate cells Homologous DNA recombination in vertebrate cells Proceedings of the National Academy of Sciences of the United States of America, 98, 15, 8388-8394 , 98, 15, 8388-8394 Proceedings of the National Academy of Sciences of the United States of America, 98, 15, 8388-8394 2001 英語 公開
S. Takeda; E.L. Masteller; C.B. Thompson; J.-M. Buerstedde S. Takeda; E.L. Masteller; C.B. Thompson; J.-M. Buerstedde RAG-2 expression is not essential for chicken immunoglobulin gene conversion RAG-2 expression is not essential for chicken immunoglobulin gene conversion Proceedings of the National Academy of Sciences of the United States of America, 89, 9, 4023-4027 , 89, 9, 4023-4027 Proceedings of the National Academy of Sciences of the United States of America, 89, 9, 4023-4027 1992 英語 公開
S. Takeda; S. Gillis; R. Palacios S. Takeda; S. Gillis; R. Palacios In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B and pro-T-lymphocyte clones and fetal thymocyte clones In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B and pro-T-lymphocyte clones and fetal thymocyte clones Proceedings of the National Academy of Sciences of the United States of America, 86, 5, 1634-1638 , 86, 5, 1634-1638 Proceedings of the National Academy of Sciences of the United States of America, 86, 5, 1634-1638 1989 英語 公開
T. Kataoka; S.I. Takeda; T. Honjo T. Kataoka; S.I. Takeda; T. Honjo Escherichia coli extract-catalyzed recombination in switch regions of mouse immunoglobulin genes Escherichia coli extract-catalyzed recombination in switch regions of mouse immunoglobulin genes Proceedings of the National Academy of Sciences of the United States of America, 80, 9 I, 2666-2670 , 80, 9 I, 2666-2670 Proceedings of the National Academy of Sciences of the United States of America, 80, 9 I, 2666-2670 1983 英語 公開
Takaku M, Tsujita T., Horikoshi N., Takizawa Y., Qing Y., Hirota K., Ikura M, Ikura T., Takeda S., Kurumizaka, H. Takaku M, Tsujita T., Horikoshi N., Takizawa Y., Qing Y., Hirota K., Ikura M, Ikura T., Takeda S., Kurumizaka, H. SMN-GEMIN2 comple χ stimulates the RAD51-mediated recombination reactions SMN-GEMIN2 comple χ stimulates the RAD51-mediated recombination reactions 第34 回日本分子生物学会年会 12 月15 日横浜 第34 回日本分子生物学会年会 12 月15 日横浜 英語 公開

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タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
Differential Functional Interactions between the RNF8 and RAD18 E3 ubiquitin ligases in Translesion DNA Synthesis and DSB Repair Differential Functional Interactions between the RNF8 and RAD18 E3 ubiquitin ligases in Translesion DNA Synthesis and DSB Repair EMBO Conference Series, Recombination & connections to SUMO and Ubiquitin modifications EMBO Conference Series, Recombination & connections to SUMO and Ubiquitin modifications EMBO EMBO 2010/05 英語 口頭発表(招待・特別) 公開
Chemical Genetic Method to Detect Environmental Mutagens and to Screen Anti-Malignant Chemical Compounds Chemical Genetic Method to Detect Environmental Mutagens and to Screen Anti-Malignant Chemical Compounds The 40th International Symposium of the Princess Takamatsu Cancer Research Fund The 40th International Symposium of the Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Reserch Fund Princess Takamatsu Cancer Reserch Fund 2009/11/11 英語 口頭発表(招待・特別) 公開
タイトル言語:
特許
発明者 発明者(日本語) 発明者(英語) 発明の名称 発明の名称(日本語) 発明の名称(英語) 審査の段階 番号 年月 公開
発明者 武田俊一、廣田耕志(独立行政法人農業生物資源研究所) 発明者 武田俊一、廣田耕志(独立行政法人農業生物資源研究所) 遺伝的に改変された細胞を製造する方法 遺伝的に改変された細胞を製造する方法 特許出願 特願特願2009-138902 2009/06/10 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(S) 代表 遺伝子破壊細胞を使った、化学物質の生物効果をハイスループットに解析するシステム 2011/04/01〜2016/03/31
挑戦的萌芽研究 代表 次世代プロテオミクスを使った、ユビキチン化によるDNA修復制御機構の生化学的解析 2011/04/01〜2013/03/31
挑戦的萌芽研究 代表 高効率で簡易な遺伝子ターゲッティング技術の開発 2013〜2014
挑戦的萌芽研究 代表 高効率で簡易な遺伝子ターゲッティング技術の開発 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(S) 代表 遺伝子破壊細胞を使った、化学物質の生物効果をハイスループットに解析するシステム (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(S) 代表 遺伝子破壊細胞を使った、化学物質の生物効果をハイスループットに解析するシステム (平成27年度分) 2015/04/01〜2016/03/31
挑戦的萌芽研究 代表 ヒト細胞のゲノム全体でDNA複製の全起点と終結点を解析する国際共同研究 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(A) 代表 ヒトゲノム編集細胞を使った、化学物質の薬理作用・有害性を解析するシステムの構築 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(S) 代表 ヒトゲノム編集細胞を使った、化学物質の薬理作用・有害性を解析するシステムの構築 (平成28年度分) 2016/04/01〜2017/03/31
化学物質リスク研究事業 代表 化審法で規定された変異原性検出試験(チミジンキナーゼ試験)を改善する手法での開発(平成28年度分) 2016/04/01〜2017/03/31
挑戦的萌芽研究 代表 ヒト細胞のゲノム全体でDNA複製の全起点と終結点を解析する国際共同研究 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(S) 代表 ヒトゲノム編集細胞を使った、化学物質の薬理作用・有害性を解析するシステムの構築 (平成29年度分) 2017/04/01〜2018/03/31
化学物質リスク研究事業 代表 (平成29年度分) 2017/04/01〜2018/03/31
化学物質リスク研究事業 代表 (平成30年度分) 2018/04/01〜2019/03/31
基盤研究(S) 代表 ヒトゲノム編集細胞を使った、化学物質の薬理作用・有害性を解析するシステムの構築 (平成30年度分) 2018/04/01〜2019/03/31

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外部資金:競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
JST戦略的国際科学技術協力推進事業 武田俊一 DNA損傷応答機構の遺伝子破壊株を使った、プロテオソーム解析による抗がん治療の為の標的分子の同定 2010/04/01〜2013/03/31
研究拠点形成事業 A.先端拠点形成型 武田 俊一 ビッグデータ解析による診断・治療法開発の国際共同研究ネットワーク (平成28年度分) 2016/04/01〜2017/03/31
研究拠点形成事業 A.先端拠点形成型 武田 俊一 ビッグデータ解析による診断・治療法開発の国際共同研究ネットワーク (平成29年度分) 2017/04/01〜2018/03/31
研究拠点形成事業 A.先端拠点形成型 武田 俊一 ビッグデータ解析による診断・治療法開発の国際共同研究ネットワーク (平成30年度分) 2018/04/01〜2019/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
基礎医学生物学
放射線生物学
B8 放射線生物学 Radiation Biology 前期 医学部 2013/04〜2014/03
放射線生物学 Radiation Biology 前期不定 医学研究科 2013/04〜2014/03
体験的医学研究入門 Hands-on medical research experience 前期集中 全学共通科目 2013/04〜2014/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2014/04〜2015/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2014/04〜2015/03
放射線生物学 Radiation Biology 前期不定 医学研究科 2014/04〜2015/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries 通年集中 医学研究科 2014/04〜2015/03
短期海外インターンシップ Internship in foreign countries 通年 工学研究科 2014/04〜2015/03
体験的医学研究入門 Hands-on medical research experience 前期集中 全学共通科目 2014/04〜2015/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2015/04〜2016/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2015/04〜2016/03
放射線生物学 Radiation Biology 前期不定 医学研究科 2015/04〜2016/03
短期海外インターンシップ Internship in foreign countries 通年 工学研究科 2015/04〜2016/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries 通年集中 医学研究科 2015/04〜2016/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2016/04〜2017/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2016/04〜2017/03
放射線生物学 Radiation Biology 前期不定 医学研究科 2016/04〜2017/03
短期海外インターンシップ Internship in foreign countries 通年 工学研究科 2016/04〜2017/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries 通年集中 医学研究科 2016/04〜2017/03
B2b 生化学実習 Laboratory Course in Biochemistry 前期 医学部 2017/04〜2018/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2017/04〜2018/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2017/04〜2018/03
放射線生物学 Radiation Biology 前期不定 医学研究科 2017/04〜2018/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries (LIMS) 通年集中 医学研究科 2017/04〜2018/03
B2b 生化学実習 Laboratory Course in Biochemistry 前期 医学部 2018/04〜2019/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2018/04〜2019/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2018/04〜2019/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries (LIMS) 通年集中 医学研究科 2018/04〜2019/03
B2b 生化学実習 Laboratory Course in Biochemistry 前期 医学部 2019/04〜2020/03
B8a 放射線生物学 Radiation Biology 前期 医学部 2019/04〜2020/03
B8b 放射線生物学実習 Laboratory Course in Radiation Biology 前期 医学部 2019/04〜2020/03
短期海外インターンシップ(LIMS) Internship in Foreign Countries (LIMS) 通年集中 医学研究科 2019/04〜2020/03

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学外非常勤講師
講義名(日本語) 講義名(英語) 開講期 学校名 学部/研究科名 期間
衛生学・公衆衛生学 大阪医科大学 2019/04/01〜2020/03/31
金沢大学
全学運営(役職等)
役職名 期間
教務体制委員
放射性同位元素等管理委員会 委員 2008/04/01〜2011/02/28
教育制度委員会 委員 2008/04/01〜2011/03/31
教養教育専門委員会 委員 2009/04/01〜2011/03/31
国際交流推進機構協議会・幹事
医学部で申請した組織的若手派遣プログラムのコーディネータ
外国人留学生奨学金等選考委員会 委員 2009/04/01〜2013/03/31
国際交流推進機構協議会 2011/04/01〜2013/03/31
国際交流推進機構協議会・幹事会 2011/04/01〜2013/03/31
京都大学公開講座等企画委員会 委員 2012/04/01〜2014/03/31
京都大学公開講座等企画委員会 委員 2013/04/01〜2014/03/31
国際交流推進機構協議会・幹事会 委員 2013/04/01〜2015/03/31
外国人留学生奨学金等選考委員会 委員 2013/04/01〜2015/03/31
京都大学国際交流推進機構協議会 協議員 2011/04/01〜2013/06/17
京都大学国際交流推進機構協議会幹事会 協議員 2011/04/01〜2013/06/17
国際関係危機管理体制検討ワーキング 委員 2014/09/19〜
外国人留学生奨学金等選考委員会 3号委員 2015/04/01〜2017/03/31
国際教育委員会留学生受入専門委員会外国人留学生奨学金等選考小委員会 委員 2016/04/01〜2018/03/31
国際教育委員会国際学生交流委員会 委員 2017/04/01〜2019/03/31
国際教育委員会国際学生交流委員会派遣小委員会 委員 2017/04/01〜2018/03/31
国際教育委員会国際学生交流委員会交換留学小委員会 委員 2018/04/01〜2019/03/31
国際教育委員会国際学生交流委員会 委員 2019/04/01〜2021/03/31
国際教育委員会国際学生交流委員会派遣小委員会 委員 2019/04/01〜2020/03/31
放射性同位元素等専門委員会 委員 2019/04/01〜2021/03/31
放射性同位元素総合センター共同利用検討委員会 2018/04/01〜2020/03/31
国際学生交流委員会 2019/04/01〜2021/03/31

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部局運営(役職等)
役職名 期間
教育体制委員会・委員
教育制度委員会・委員
医学研究科医科学専攻運営委員会・委員長
医の倫理委員会小委員会・委員
国際交流委員会・委員 〜2020/09/30
医の倫理委員会(親委員会)・委員
動物実験施設運営委員会
医学研究科・医学部放射性同位元素等管理委員会
医学研究科等安全衛生委員会 2013/04/01〜2020/03/31
医学研究科運営委員会 〜2014/09/30
医学部学務委員会 2012/05/10〜2018/03/31
放射性同位元素等管理委員会
環境安全保健機構附属放射性同位元素総合センター共同利用検討委員会 2016/04/01〜2018/03/31
放射線障害防止委員会

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