CANDEIAS MarcoMarques

最終更新日時: 2018/06/28 15:39:09

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氏名(漢字/フリガナ/アルファベット表記)
CANDEIAS MarcoMarques/キャンディアス マルコマルケス/Candeias, Marcomarques
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学研究科附属医学教育・国際化推進センター/国際化推進部門/講師
学部兼担
部局 所属 講座等 職名
医学部
国際高等教育院
連絡先電話番号
種別 番号
職場 +81 (0)75-753-9297
全学電子メールアドレス
candeias.marcomarques.8r @ kyoto-u.ac.jp
個人ホームページ
URL
areap53.com
researchmap URL
https://researchmap.jp/7000015494
研究テーマ
(英語)
p53; p53 mRNA; p53 isoforms; mRNA functions in cancer pathways
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Marques-Ramos A, Candeias MM, Menezes J, Lacerda R, Willcocks M, Teixeira A, Locker N, Romão L Marques-Ramos A, Candeias MM, Menezes J, Lacerda R, Willcocks M, Teixeira A, Locker N, Romão L Marques-Ramos A, Candeias MM, Menezes J, Lacerda R, Willcocks M, Teixeira A, Locker N, Romão L Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition. Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition. Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition. RNA (New York, N.Y.), 23, 11, 1712-1728 RNA (New York, N.Y.), 23, 11, 1712-1728 RNA (New York, N.Y.), 23, 11, 1712-1728 2017/11 公開
Candeias MM, Hagiwara M, Matsuda M Candeias MM, Hagiwara M, Matsuda M Candeias MM, Hagiwara M, Matsuda M Cancer-specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis. Cancer-specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis. Cancer-specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis. EMBO reports, 17, 11, 1542-1551 EMBO reports, 17, 11, 1542-1551 EMBO reports, 17, 11, 1542-1551 2016/11 公開
Sumitomo Y, Higashitsuji H, Higashitsuji H, Liu Y, Fujita T, Sakurai T, Candeias MM, Itoh K, Chiba T, Fujita J Sumitomo Y, Higashitsuji H, Higashitsuji H, Liu Y, Fujita T, Sakurai T, Candeias MM, Itoh K, Chiba T, Fujita J Sumitomo Y, Higashitsuji H, Higashitsuji H, Liu Y, Fujita T, Sakurai T, Candeias MM, Itoh K, Chiba T, Fujita J Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells. Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells. Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells. BMC biotechnology, 12, 72 BMC biotechnology, 12, 72 BMC biotechnology, 12, 72 2012/10 公開
Gajjar M, Candeias MM, Malbert-Colas L, Mazars A, Fujita J, Olivares-Illana V, Fåhraeus R Gajjar M, Candeias MM, Malbert-Colas L, Mazars A, Fujita J, Olivares-Illana V, Fåhraeus R Gajjar M, Candeias MM, Malbert-Colas L, Mazars A, Fujita J, Olivares-Illana V, Fåhraeus R The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage. The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage. The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage. Cancer cell, 21, 1, 25-35 Cancer cell, 21, 1, 25-35 Cancer cell, 21, 1, 25-35 2012/01 公開
Candeias MM Candeias MM Candeias MM The can and can't dos of p53 RNA. The can and can't dos of p53 RNA. The can and can't dos of p53 RNA. Biochimie, 93, 11, 1962-1965 Biochimie, 93, 11, 1962-1965 Biochimie, 93, 11, 1962-1965 2011/11 公開
Bourougaa K, Naski N, Boularan C, Mlynarczyk C, Candeias MM, Marullo S, Fåhraeus R Bourougaa K, Naski N, Boularan C, Mlynarczyk C, Candeias MM, Marullo S, Fåhraeus R Bourougaa K, Naski N, Boularan C, Mlynarczyk C, Candeias MM, Marullo S, Fåhraeus R Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Molecular cell, 38, 1, 78-88 Molecular cell, 38, 1, 78-88 Molecular cell, 38, 1, 78-88 2010/04 公開
Bruzzoni-Giovanelli H, Fernandez P, Veiga L, Podgorniak MP, Powell DJ, Candeias MM, Mourah S, Calvo F, Marín M Bruzzoni-Giovanelli H, Fernandez P, Veiga L, Podgorniak MP, Powell DJ, Candeias MM, Mourah S, Calvo F, Marín M Bruzzoni-Giovanelli H, Fernandez P, Veiga L, Podgorniak MP, Powell DJ, Candeias MM, Mourah S, Calvo F, Marín M Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes. Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes. Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes. Journal of experimental & clinical cancer research : CR, 29, 10 Journal of experimental & clinical cancer research : CR, 29, 10 Journal of experimental & clinical cancer research : CR, 29, 10 2010/02 公開
Grover R, Candeias MM, Fåhraeus R, Das S Grover R, Candeias MM, Fåhraeus R, Das S Grover R, Candeias MM, Fåhraeus R, Das S p53 and little brother p53/47: linking IRES activities with protein functions. p53 and little brother p53/47: linking IRES activities with protein functions. p53 and little brother p53/47: linking IRES activities with protein functions. Oncogene, 28, 30, 2766-2772 Oncogene, 28, 30, 2766-2772 Oncogene, 28, 30, 2766-2772 2009/07 公開
Naski N, Gajjar M, Bourougaa K, Malbert-Colas L, Fåhraeus R, Candeias MM Naski N, Gajjar M, Bourougaa K, Malbert-Colas L, Fåhraeus R, Candeias MM Naski N, Gajjar M, Bourougaa K, Malbert-Colas L, Fåhraeus R, Candeias MM The p53 mRNA-Mdm2 interaction. The p53 mRNA-Mdm2 interaction. The p53 mRNA-Mdm2 interaction. Cell cycle (Georgetown, Tex.), 8, 1, 31-34 Cell cycle (Georgetown, Tex.), 8, 1, 31-34 Cell cycle (Georgetown, Tex.), 8, 1, 31-34 2009/01 公開
Daskalogianni C, Apcher S, Candeias MM, Naski N, Calvo F, Fåhraeus R Daskalogianni C, Apcher S, Candeias MM, Naski N, Calvo F, Fåhraeus R Daskalogianni C, Apcher S, Candeias MM, Naski N, Calvo F, Fåhraeus R Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing. Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing. Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing. The Journal of biological chemistry, 283, 44, 30090-30100 The Journal of biological chemistry, 283, 44, 30090-30100 The Journal of biological chemistry, 283, 44, 30090-30100 2008/10 公開
Candeias MM, Malbert-Colas L, Powell DJ, Daskalogianni C, Maslon MM, Naski N, Bourougaa K, Calvo F, Fåhraeus R Candeias MM, Malbert-Colas L, Powell DJ, Daskalogianni C, Maslon MM, Naski N, Bourougaa K, Calvo F, Fåhraeus R Candeias MM, Malbert-Colas L, Powell DJ, Daskalogianni C, Maslon MM, Naski N, Bourougaa K, Calvo F, Fåhraeus R P53 mRNA controls p53 activity by managing Mdm2 functions. P53 mRNA controls p53 activity by managing Mdm2 functions. P53 mRNA controls p53 activity by managing Mdm2 functions. Nature cell biology, 10, 9, 1098-1105 Nature cell biology, 10, 9, 1098-1105 Nature cell biology, 10, 9, 1098-1105 2008/09 公開
Hrstka R, Powell DJ, Kvardova V, Roubalova E, Bourougaa K, Candeias MM, Sova P, Zak F, Fåhraeus R, Vojtĕsek B Hrstka R, Powell DJ, Kvardova V, Roubalova E, Bourougaa K, Candeias MM, Sova P, Zak F, Fåhraeus R, Vojtĕsek B Hrstka R, Powell DJ, Kvardova V, Roubalova E, Bourougaa K, Candeias MM, Sova P, Zak F, Fåhraeus R, Vojtĕsek B The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin. The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin. The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin. Anti-cancer drugs, 19, 4, 369-379 Anti-cancer drugs, 19, 4, 369-379 Anti-cancer drugs, 19, 4, 369-379 2008/04 公開
Powell DJ, Hrstka R, Candeias M, Bourougaa K, Vojtesek B, Fåhraeus R Powell DJ, Hrstka R, Candeias M, Bourougaa K, Vojtesek B, Fåhraeus R Powell DJ, Hrstka R, Candeias M, Bourougaa K, Vojtesek B, Fåhraeus R Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47. Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47. Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47. Cell cycle (Georgetown, Tex.), 7, 7, 950-959 Cell cycle (Georgetown, Tex.), 7, 7, 950-959 Cell cycle (Georgetown, Tex.), 7, 7, 950-959 2008/04 公開
Candeias MM, Powell DJ, Roubalova E, Apcher S, Bourougaa K, Vojtesek B, Bruzzoni-Giovanelli H, Fåhraeus R Candeias MM, Powell DJ, Roubalova E, Apcher S, Bourougaa K, Vojtesek B, Bruzzoni-Giovanelli H, Fåhraeus R Candeias MM, Powell DJ, Roubalova E, Apcher S, Bourougaa K, Vojtesek B, Bruzzoni-Giovanelli H, Fåhraeus R Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation. Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation. Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation. Oncogene, 25, 52, 6936-6947 Oncogene, 25, 52, 6936-6947 Oncogene, 25, 52, 6936-6947 2006/11 公開

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タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
若手研究(B) 代表 Hotspot Synonymous Cancer Mutations Part 1: Effect on Cap-independent Translation of New HRAS Isoform (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 Studying and targeting a proto-oncogenic Internal Ribosome Entry Site (IRES) in p53 mRNA that is activated by the most frequent mutations in cancer 2018/04/01〜2021/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
ILAS Seminar-E2 ILAS Seminar-E2 前期 全学共通科目 2016/04〜2017/03
Introduction to Biochemistry-E2 Introduction to Biochemistry-E2 後期 全学共通科目 2016/04〜2017/03
ILAS Seminar-E2 ILAS Seminar-E2 前期 全学共通科目 2017/04〜2018/03
Introduction to Biochemistry-E2 Introduction to Biochemistry-E2 後期 全学共通科目 2017/04〜2018/03
ILAS Seminar-E2 ILAS Seminar-E2 前期 全学共通科目 2018/04〜2019/03
Introduction to Biochemistry-E2 Introduction to Biochemistry-E2 後期 全学共通科目 2018/04〜2019/03
学外学位論文審査
学位取得者名 学位論文タイトル 大学名 国名 役割 年月
Cristina Maria Botelho da Rocha Barbosa Master University of Lisbon Portugal 主査 2013/12/16