高橋 めい子

最終更新日時: 2019/06/04 14:59:30

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氏名(漢字/フリガナ/アルファベット表記)
高橋 めい子/タカハシ メイコ/Takahashi, Meiko
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学研究科附属ゲノム医学センター/疾患ゲノム疫学/特定講師
学部兼担
部局 所属 講座等 職名
医学部
所属学会(国内)
学会名(日本語) 学会名(英語)
日本癌学会 Japanese Cancer Association
日本人類遺伝学会 The Japan Society of Human Genetics
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
Ph.D. ロンドン大学
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
2000/08/01〜2003/09/30 東京大学医科学研究所ヒトゲノム解析センター Human Genome Center, University of Tokyo リサーチアソシエイト Research Associate
2003/10/01〜2007/03/31 京都大学医学研究科 先端領域融合研究機構 HMRO, Kyoto University 助手 Assistant Professor
2007/04/01〜2014/03/31 京都大学医学研究科附属ゲノム医学センター 疾患ゲノム疫学解析分野 Center for Genomic Medicine, Kyoto University 助教 Assistant Professor
2014/04/01〜2016/11/30 京都大学学際融合教育研究推進センター Center for the Promotion of Interdisciplinary Education and Research, Kyoto University 特定講師 Senior Lecturer
2016/12/01〜2019/03/31 京都大学大学院医学研究科 Kyoto University Graduate School of Medicine 特定講師 Senior Lecturer
2019/04/01〜2020/03/31 京都大学医学研究科附属ゲノム医学センター Center for Genomic Medicine, Kyoto University Graduate School of Medicine 特定講師 Senior Lecturer
使用言語
言語名
英語
researchmap URL
https://researchmap.jp/7000008426
研究テーマ
(日本語)
癌遺伝学、ゲノムワイド関連解析(GWAS)
(英語)
Cancer Genetics, Genome-wide association study (GWAS)
研究概要
(日本語)
ヒトゲノムの塩基配列には、個人間、人種間で微妙な違いが多数存在する。これら塩基の個体差を多型と呼び、そのうち一塩基の多型 (Single Nucleotide Polymorphism: SNP) はヒトゲノム上で数百塩基に一箇所の割合で存在し、疾患と個人の遺伝的素因の関係を調べる有用なツールとなっている。近年ではDNAチップの開発により全ゲノム関連解析(GWAS)が可能になった。患者と対照群について数十万個のSNP遺伝子型データを一度に決定し、両群で有意差を認めるSNPを探索することにより疾患発症に重要な影響を及ぼす遺伝子多型が同定可能である。我々の目的はGWASを用いて、様々な多因子型遺伝病の感受性遺伝子多型を同定し、その情報を基に高危険群診断法の確立することである。
(英語)
Our principle aim is the identification of genes related to the onset and progression of various human multigenetic diseases by genome-wide association studies (GWAS).
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Imaizumi A, Adachi Y, Kawaguchi T, Higasa K, Tabara Y, Sonomura K, Sato TA, Takahashi M, Mizukoshi T, Yoshida HO, Kageyama N, Okamoto C, Takasu M, Mori M, Noguchi Y, Shimba N, Miyano H, Yamada R, Matsuda F Imaizumi A, Adachi Y, Kawaguchi T, Higasa K, Tabara Y, Sonomura K, Sato TA, Takahashi M, Mizukoshi T, Yoshida HO, Kageyama N, Okamoto C, Takasu M, Mori M, Noguchi Y, Shimba N, Miyano H, Yamada R, Matsuda F Imaizumi A, Adachi Y, Kawaguchi T, Higasa K, Tabara Y, Sonomura K, Sato TA, Takahashi M, Mizukoshi T, Yoshida HO, Kageyama N, Okamoto C, Takasu M, Mori M, Noguchi Y, Shimba N, Miyano H, Yamada R, Matsuda F Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. European journal of human genetics : EJHG, 27, 4, 621-630 European journal of human genetics : EJHG, 27, 4, 621-630 European journal of human genetics : EJHG, 27, 4, 621-630 2019/04 公開
Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A, Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A, Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, Kochi Y, Suda T, Tanemoto K, Meguro A, Okada Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Kuwana M, Mizuki N, Tabara Y, Ueda A, Komuro I, Kimura A, Isobe M, Mimori T, Matsuda F Genetic determinants and an epistasis of <i>LILRA3</i> and HLA-B*52 in Takayasu arteritis. Genetic determinants and an epistasis of <i>LILRA3</i> and HLA-B*52 in Takayasu arteritis. Genetic determinants and an epistasis of <i>LILRA3</i> and HLA-B*52 in Takayasu arteritis. Proceedings of the National Academy of Sciences of the United States of America, 115, 51, 13045-13050 Proceedings of the National Academy of Sciences of the United States of America, 115, 51, 13045-13050 Proceedings of the National Academy of Sciences of the United States of America, 115, 51, 13045-13050 2018/12 公開
Kawaguchi T, Shima T, Mizuno M, Mitsumoto Y, Umemura A, Kanbara Y, Tanaka S, Sumida Y, Yasui K, Takahashi M, Matsuo K, Itoh Y, Tokushige K, Hashimoto E, Kiyosawa K, Kawaguchi M, Itoh H, Uto H, Komorizono Y, Shirabe K, Takami S, Takamura T, Kawanaka M, Yamada R, Matsuda F, Okanoue T Kawaguchi T, Shima T, Mizuno M, Mitsumoto Y, Umemura A, Kanbara Y, Tanaka S, Sumida Y, Yasui K, Takahashi M, Matsuo K, Itoh Y, Tokushige K, Hashimoto E, Kiyosawa K, Kawaguchi M, Itoh H, Uto H, Komorizono Y, Shirabe K, Takami S, Takamura T, Kawanaka M, Yamada R, Matsuda F, Okanoue T Kawaguchi T, Shima T, Mizuno M, Mitsumoto Y, Umemura A, Kanbara Y, Tanaka S, Sumida Y, Yasui K, Takahashi M, Matsuo K, Itoh Y, Tokushige K, Hashimoto E, Kiyosawa K, Kawaguchi M, Itoh H, Uto H, Komorizono Y, Shirabe K, Takami S, Takamura T, Kawanaka M, Yamada R, Matsuda F, Okanoue T Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. PloS one, 13, 1, e0185490 PloS one, 13, 1, e0185490 PloS one, 13, 1, e0185490 2018 公開
Nakatochi M, Lin Y, Ito H, Hara K, Kinoshita F, Kobayashi Y, Ishii H, Ozaka M, Sasaki T, Sasahira N, Morimoto M, Kobayashi S, Ueno M, Ohkawa S, Egawa N, Kuruma S, Mori M, Nakao H, Wang C, Nishiyama T, Kawaguchi T, Takahashi M, Matsuda F, Kikuchi S, Matsuo K Nakatochi M, Lin Y, Ito H, Hara K, Kinoshita F, Kobayashi Y, Ishii H, Ozaka M, Sasaki T, Sasahira N, Morimoto M, Kobayashi S, Ueno M, Ohkawa S, Egawa N, Kuruma S, Mori M, Nakao H, Wang C, Nishiyama T, Kawaguchi T, Takahashi M, Matsuda F, Kikuchi S, Matsuo K Nakatochi M, Lin Y, Ito H, Hara K, Kinoshita F, Kobayashi Y, Ishii H, Ozaka M, Sasaki T, Sasahira N, Morimoto M, Kobayashi S, Ueno M, Ohkawa S, Egawa N, Kuruma S, Mori M, Nakao H, Wang C, Nishiyama T, Kawaguchi T, Takahashi M, Matsuda F, Kikuchi S, Matsuo K Prediction model for pancreatic cancer risk in the general Japanese population. Prediction model for pancreatic cancer risk in the general Japanese population. Prediction model for pancreatic cancer risk in the general Japanese population. PloS one, 13, 9, e0203386 PloS one, 13, 9, e0203386 PloS one, 13, 9, e0203386 2018 公開
Terao, C., Kawaguchi, T., Dieude, P., Varga, J., Kuwana, M., Hudson, M., Kawaguchi, Y., Matucci-Cerinic, M., Ohmura, K., Riemekasten, G., Kawasaki, A., Airo, P., Horita, T., Oka, A., Hachulla, E., Yoshifuji, H., Caramaschi, P., Hunzelmann, N., Baron, M., Atsumi, T., Hassoun, P., Torii, T., Takahashi, M., Tabara, Y., Shimizu, M., Tochimoto, A., Ayuzawa, N., Yanagida, H., Furukawa, H., Tohma, S., Hasegawa, M., Fujimoto, M., Ishikawa, O., Yamamoto, T., Goto, D., Asano, Y., Jinnin, M., Endo, H., Takahashi, H., Takehara, K., Sato, S., Ihn, H., Raychaudhuri, S., Liao, K., Gregersen, P., Tsuchiya, N., Riccieri, V., Melchers, I., Valentini, G., Cauvet, A., Martinez, M., Mimori, T., Matsuda, F., Allanore, Y Terao, C., Kawaguchi, T., Dieude, P., Varga, J., Kuwana, M., Hudson, M., Kawaguchi, Y., Matucci-Cerinic, M., Ohmura, K., Riemekasten, G., Kawasaki, A., Airo, P., Horita, T., Oka, A., Hachulla, E., Yoshifuji, H., Caramaschi, P., Hunzelmann, N., Baron, M., Atsumi, T., Hassoun, P., Torii, T., Takahashi, M., Tabara, Y., Shimizu, M., Tochimoto, A., Ayuzawa, N., Yanagida, H., Furukawa, H., Tohma, S., Hasegawa, M., Fujimoto, M., Ishikawa, O., Yamamoto, T., Goto, D., Asano, Y., Jinnin, M., Endo, H., Takahashi, H., Takehara, K., Sato, S., Ihn, H., Raychaudhuri, S., Liao, K., Gregersen, P., Tsuchiya, N., Riccieri, V., Melchers, I., Valentini, G., Cauvet, A., Martinez, M., Mimori, T., Matsuda, F., Allanore, Y Terao, C., Kawaguchi, T., Dieude, P., Varga, J., Kuwana, M., Hudson, M., Kawaguchi, Y., Matucci-Cerinic, M., Ohmura, K., Riemekasten, G., Kawasaki, A., Airo, P., Horita, T., Oka, A., Hachulla, E., Yoshifuji, H., Caramaschi, P., Hunzelmann, N., Baron, M., Atsumi, T., Hassoun, P., Torii, T., Takahashi, M., Tabara, Y., Shimizu, M., Tochimoto, A., Ayuzawa, N., Yanagida, H., Furukawa, H., Tohma, S., Hasegawa, M., Fujimoto, M., Ishikawa, O., Yamamoto, T., Goto, D., Asano, Y., Jinnin, M., Endo, H., Takahashi, H., Takehara, K., Sato, S., Ihn, H., Raychaudhuri, S., Liao, K., Gregersen, P., Tsuchiya, N., Riccieri, V., Melchers, I., Valentini, G., Cauvet, A., Martinez, M., Mimori, T., Matsuda, F., Allanore, Y Trans-ethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis Trans-ethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis Trans-ethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis Ann Rheum Dis, 76, 6, 1150-1158 Ann Rheum Dis, 76, 6, 1150-1158 Ann Rheum Dis, 76, 6, 1150-1158 2017/06 英語 研究論文(学術雑誌) 公開
Nikitski, A.V., Rogounovitch, T.I., Bychkov, A., Takahashi, M., Yoshiura, K., Mitsutake, N., Kawaguchi ,T., Matsuse, M., Drozd, V.M., Demidchik, Y., Nishihara, E., Hirokawa, M., Miyauchi, A., Rubanovich, A.V., Matsuda, F., Yamashita, S., and Saenko, V.A Nikitski, A.V., Rogounovitch, T.I., Bychkov, A., Takahashi, M., Yoshiura, K., Mitsutake, N., Kawaguchi ,T., Matsuse, M., Drozd, V.M., Demidchik, Y., Nishihara, E., Hirokawa, M., Miyauchi, A., Rubanovich, A.V., Matsuda, F., Yamashita, S., and Saenko, V.A Nikitski, A.V., Rogounovitch, T.I., Bychkov, A., Takahashi, M., Yoshiura, K., Mitsutake, N., Kawaguchi ,T., Matsuse, M., Drozd, V.M., Demidchik, Y., Nishihara, E., Hirokawa, M., Miyauchi, A., Rubanovich, A.V., Matsuda, F., Yamashita, S., and Saenko, V.A Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma , 27, 2, 224-235 , 27, 2, 224-235 , 27, 2, 224-235 2017/02 英語 研究論文(学術雑誌) 公開
Muro, S., Tabara, Y., Matsumoto, H., Setoh, K., Kawaguchi, T., Takahashi, M., Ito, I., Ito, Y., Murase, K., Terao, C., Kosugi, S., Yamada, R., Sekine, A., Nakayama, T., Chin, K., Mishima, M., Matsuda F; Nagahama Study Group Muro, S., Tabara, Y., Matsumoto, H., Setoh, K., Kawaguchi, T., Takahashi, M., Ito, I., Ito, Y., Murase, K., Terao, C., Kosugi, S., Yamada, R., Sekine, A., Nakayama, T., Chin, K., Mishima, M., Matsuda F; Nagahama Study Group Muro, S., Tabara, Y., Matsumoto, H., Setoh, K., Kawaguchi, T., Takahashi, M., Ito, I., Ito, Y., Murase, K., Terao, C., Kosugi, S., Yamada, R., Sekine, A., Nakayama, T., Chin, K., Mishima, M., Matsuda F; Nagahama Study Group Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study Medicine, 95, 15, e3371 Medicine, 95, 15, e3371 Medicine, 95, 15, e3371 2016/04 英語 研究論文(学術雑誌) 公開
Tabara, Y., Takahashi, Y., Kumagai, K., Setoh, K., Kawaguchi, T., Takahashi, M., Muraoka, Y., Tsujikawa, A., Gotoh, N., Terao, C., Yamada, R., Kosugi, S., Sekine, A., Yoshimura, N., Nakayama, T., Matsuda, F.; Nagahama study group Tabara, Y., Takahashi, Y., Kumagai, K., Setoh, K., Kawaguchi, T., Takahashi, M., Muraoka, Y., Tsujikawa, A., Gotoh, N., Terao, C., Yamada, R., Kosugi, S., Sekine, A., Yoshimura, N., Nakayama, T., Matsuda, F.; Nagahama study group Tabara, Y., Takahashi, Y., Kumagai, K., Setoh, K., Kawaguchi, T., Takahashi, M., Muraoka, Y., Tsujikawa, A., Gotoh, N., Terao, C., Yamada, R., Kosugi, S., Sekine, A., Yoshimura, N., Nakayama, T., Matsuda, F.; Nagahama study group Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study J Hypertens, 33, 12, 2407-2413 J Hypertens, 33, 12, 2407-2413 J Hypertens, 33, 12, 2407-2413 2015/12 英語 研究論文(学術雑誌) 公開
Terao, C., Yamakawa, N., Yano, K., Markusse, I.M., Ikari, K., Yoshida, S., Furu, M., Hashimoto, M., Ito, H., Fujii, T., Ohmura, K., Murakami, K., Takahashi, M., Hamaguchi, M., Tabara, Y., Taniguchi, A., Momohara, S., Raychaudhuri, S., Allaart, C.F., Yamanaka, H., Mimori, T., Matsuda, F Terao, C., Yamakawa, N., Yano, K., Markusse, I.M., Ikari, K., Yoshida, S., Furu, M., Hashimoto, M., Ito, H., Fujii, T., Ohmura, K., Murakami, K., Takahashi, M., Hamaguchi, M., Tabara, Y., Taniguchi, A., Momohara, S., Raychaudhuri, S., Allaart, C.F., Yamanaka, H., Mimori, T., Matsuda, F Terao, C., Yamakawa, N., Yano, K., Markusse, I.M., Ikari, K., Yoshida, S., Furu, M., Hashimoto, M., Ito, H., Fujii, T., Ohmura, K., Murakami, K., Takahashi, M., Hamaguchi, M., Tabara, Y., Taniguchi, A., Momohara, S., Raychaudhuri, S., Allaart, C.F., Yamanaka, H., Mimori, T., Matsuda, F Rheumatoid Factor Is Associated With the Distribution of Hand Joint Destruction in Rheumatoid Arthritis Rheumatoid Factor Is Associated With the Distribution of Hand Joint Destruction in Rheumatoid Arthritis Rheumatoid Factor Is Associated With the Distribution of Hand Joint Destruction in Rheumatoid Arthritis Arthritis Rheumatol, 67, 12, 3113-3123 Arthritis Rheumatol, 67, 12, 3113-3123 Arthritis Rheumatol, 67, 12, 3113-3123 2015/12 英語 研究論文(学術雑誌) 公開
Sahasrabudhe, R., Estrada, A., Lott, P., Martin, L., Echeverry, G.P., Velez, A., Neta, G., Takahashi, M., Saenko, V., Mitsutake, N., on behalf of the JTCMS Consortium, Jaeguer, E., Duque, C.S., Rios, A., Bohorquez, M., Prieto, R., Criollo, A., Echeverry, M., Tomlinson, I., on behalf of the TCUKIN and CORGI Consortiums and Carmona, L.G.C Sahasrabudhe, R., Estrada, A., Lott, P., Martin, L., Echeverry, G.P., Velez, A., Neta, G., Takahashi, M., Saenko, V., Mitsutake, N., on behalf of the JTCMS Consortium, Jaeguer, E., Duque, C.S., Rios, A., Bohorquez, M., Prieto, R., Criollo, A., Echeverry, M., Tomlinson, I., on behalf of the TCUKIN and CORGI Consortiums and Carmona, L.G.C Sahasrabudhe, R., Estrada, A., Lott, P., Martin, L., Echeverry, G.P., Velez, A., Neta, G., Takahashi, M., Saenko, V., Mitsutake, N., on behalf of the JTCMS Consortium, Jaeguer, E., Duque, C.S., Rios, A., Bohorquez, M., Prieto, R., Criollo, A., Echeverry, M., Tomlinson, I., on behalf of the TCUKIN and CORGI Consortiums and Carmona, L.G.C The 8q24 rs6983267G variant is associated with increased thyroid cancer risk The 8q24 rs6983267G variant is associated with increased thyroid cancer risk The 8q24 rs6983267G variant is associated with increased thyroid cancer risk Endocr Relat Cancer, 22, 5, 841-849 Endocr Relat Cancer, 22, 5, 841-849 Endocr Relat Cancer, 22, 5, 841-849 2015/10 英語 研究論文(学術雑誌) 公開
Setoh, K., Terao, C., Muro, S., Kawaguchi, T., Tabara, Y., Takahashi, M., Nakayama, T., Kosugi, S., Sekine, A., Yamada, R., Mishima, M., Matsuda, F Setoh, K., Terao, C., Muro, S., Kawaguchi, T., Tabara, Y., Takahashi, M., Nakayama, T., Kosugi, S., Sekine, A., Yamada, R., Mishima, M., Matsuda, F Setoh, K., Terao, C., Muro, S., Kawaguchi, T., Tabara, Y., Takahashi, M., Nakayama, T., Kosugi, S., Sekine, A., Yamada, R., Mishima, M., Matsuda, F Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels Nat Commun, 6, 7754 Nat Commun, 6, 7754 Nat Commun, 6, 7754 2015/07 英語 研究論文(学術雑誌) 公開
Terao C, Asai K, Hashimoto M, Yamazaki T, Ohmura K, Yamaguchi A, Takahashi K, Takei N, Ishii T, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Fujii T, Yamada R, Mimori T, Matsuda F, Bessho K, Nagahama Study Group Terao C, Asai K, Hashimoto M, Yamazaki T, Ohmura K, Yamaguchi A, Takahashi K, Takei N, Ishii T, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Fujii T, Yamada R, Mimori T, Matsuda F, Bessho K, Nagahama Study Group Terao C, Asai K, Hashimoto M, Yamazaki T, Ohmura K, Yamaguchi A, Takahashi K, Takei N, Ishii T, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Fujii T, Yamada R, Mimori T, Matsuda F, Bessho K, Nagahama Study Group Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population - The Nagahama study. Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population - The Nagahama study. Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population - The Nagahama study. Journal of autoimmunity, 59, 85-90 Journal of autoimmunity, 59, 85-90 Journal of autoimmunity, 59, 85-90 2015/05 公開
Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Nakaoka Y, Takahashi M, Amiya E, Tamura N, Nakajima T, Origuchi T, Horita T, Matsukura M, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Nakaoka Y, Takahashi M, Amiya E, Tamura N, Nakajima T, Origuchi T, Horita T, Matsukura M, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Nakaoka Y, Takahashi M, Amiya E, Tamura N, Nakajima T, Origuchi T, Horita T, Matsukura M, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F Takayasu arteritis and ulcerative colitis -high concurrence ratio and genetic overlap. Takayasu arteritis and ulcerative colitis -high concurrence ratio and genetic overlap. Takayasu arteritis and ulcerative colitis -high concurrence ratio and genetic overlap. Arthritis & rheumatology (Hoboken, N.J.) Arthritis & rheumatology (Hoboken, N.J.) Arthritis & rheumatology (Hoboken, N.J.) 2015/04 公開
Terao C, Ohmura K, Kochi Y, Ikari K, Okada Y, Shimizu M, Nishina N, Suzuki A, Myouzen K, Kawaguchi T, Takahashi M, Takasugi K, Murasawa A, Mizuki S, Iwahashi M, Funahashi K, Natsumeda M, Furu M, Hashimoto M, Ito H, Fujii T, Ezawa K, Matsubara T, Takeuchi T, Kubo M, Yamada R, Taniguchi A, Yamanaka H, Momohara S, Yamamoto K, Mimori T, Matsuda F Terao C, Ohmura K, Kochi Y, Ikari K, Okada Y, Shimizu M, Nishina N, Suzuki A, Myouzen K, Kawaguchi T, Takahashi M, Takasugi K, Murasawa A, Mizuki S, Iwahashi M, Funahashi K, Natsumeda M, Furu M, Hashimoto M, Ito H, Fujii T, Ezawa K, Matsubara T, Takeuchi T, Kubo M, Yamada R, Taniguchi A, Yamanaka H, Momohara S, Yamamoto K, Mimori T, Matsuda F Terao C, Ohmura K, Kochi Y, Ikari K, Okada Y, Shimizu M, Nishina N, Suzuki A, Myouzen K, Kawaguchi T, Takahashi M, Takasugi K, Murasawa A, Mizuki S, Iwahashi M, Funahashi K, Natsumeda M, Furu M, Hashimoto M, Ito H, Fujii T, Ezawa K, Matsubara T, Takeuchi T, Kubo M, Yamada R, Taniguchi A, Yamanaka H, Momohara S, Yamamoto K, Mimori T, Matsuda F Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population. Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population. Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population. Arthritis research & therapy, 17, 1, 104 Arthritis research & therapy, 17, 1, 104 Arthritis research & therapy, 17, 1, 104 2015/04 公開
Rogounovitch TI, Bychkov A, Takahashi M, Mitsutake N, Nakashima M, Nikitski AV, Hayashi T, Hirokawa M, Ishigaki K, Shigematsu K, Bogdanova T, Matsuse M, Nishihara E, Minami S, Yamanouchi K, Ito M, Kawaguchi T, Kondo H, Takamura N, Ito Y, Miyauchi A, Matsuda F, Yamashita S, Saenko VA Rogounovitch TI, Bychkov A, Takahashi M, Mitsutake N, Nakashima M, Nikitski AV, Hayashi T, Hirokawa M, Ishigaki K, Shigematsu K, Bogdanova T, Matsuse M, Nishihara E, Minami S, Yamanouchi K, Ito M, Kawaguchi T, Kondo H, Takamura N, Ito Y, Miyauchi A, Matsuda F, Yamashita S, Saenko VA Rogounovitch TI, Bychkov A, Takahashi M, Mitsutake N, Nakashima M, Nikitski AV, Hayashi T, Hirokawa M, Ishigaki K, Shigematsu K, Bogdanova T, Matsuse M, Nishihara E, Minami S, Yamanouchi K, Ito M, Kawaguchi T, Kondo H, Takamura N, Ito Y, Miyauchi A, Matsuda F, Yamashita S, Saenko VA The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population. The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population. The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population. Thyroid : official journal of the American Thyroid Association, 25, 3, 333-340 Thyroid : official journal of the American Thyroid Association, 25, 3, 333-340 Thyroid : official journal of the American Thyroid Association, 25, 3, 333-340 2015/03 英語 研究論文(学術雑誌) 公開
Ebi H, Oze I, Nakagawa T, Ito H, Hosono S, Matsuda F, Takahashi M, Takeuchi S, Sakao Y, Hida T, Faber AC, Tanaka H, Yatabe Y, Mitsudomi T, Yano S, Matsuo K Ebi H, Oze I, Nakagawa T, Ito H, Hosono S, Matsuda F, Takahashi M, Takeuchi S, Sakao Y, Hida T, Faber AC, Tanaka H, Yatabe Y, Mitsudomi T, Yano S, Matsuo K Ebi H, Oze I, Nakagawa T, Ito H, Hosono S, Matsuda F, Takahashi M, Takeuchi S, Sakao Y, Hida T, Faber AC, Tanaka H, Yatabe Y, Mitsudomi T, Yano S, Matsuo K Lack of association between the BIM deletion polymorphism and the risk of lung cancer with and without EGFR mutations. Lack of association between the BIM deletion polymorphism and the risk of lung cancer with and without EGFR mutations. Lack of association between the BIM deletion polymorphism and the risk of lung cancer with and without EGFR mutations. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 10, 1, 59-66 Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 10, 1, 59-66 Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 10, 1, 59-66 2015/01 公開
Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Mimori T, Nagahama Study Group Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Mimori T, Nagahama Study Group Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Mimori T, Nagahama Study Group Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study. Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study. Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study. Arthritis & rheumatology (Hoboken, N.J.), 66, 12, 3395-3403 Arthritis & rheumatology (Hoboken, N.J.), 66, 12, 3395-3403 Arthritis & rheumatology (Hoboken, N.J.), 66, 12, 3395-3403 2014/12 公開
Terao C, Ohmura K, Ikari K, Kawaguchi T, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Tabara Y, Taniguchi A, Momohara S, Yamanaka H, Yamada R, Matsuda F, Mimori T, Nagahama Study Group Terao C, Ohmura K, Ikari K, Kawaguchi T, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Tabara Y, Taniguchi A, Momohara S, Yamanaka H, Yamada R, Matsuda F, Mimori T, Nagahama Study Group Terao C, Ohmura K, Ikari K, Kawaguchi T, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Tabara Y, Taniguchi A, Momohara S, Yamanaka H, Yamada R, Matsuda F, Mimori T, Nagahama Study Group Effects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adult population. Effects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adult population. Effects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adult population. Arthritis care & research, 66, 12, 1818-1827 Arthritis care & research, 66, 12, 1818-1827 Arthritis care & research, 66, 12, 1818-1827 2014/12 公開
Terao C, Terada N, Matsuo K, Kawaguchi T, Yoshimura K, Hayashi N, Shimizu M, Soga N, Takahashi M, Nagahama Cohort Study Group, Kotoura Y, Yamada R, Ogawa O, Matsuda F Terao C, Terada N, Matsuo K, Kawaguchi T, Yoshimura K, Hayashi N, Shimizu M, Soga N, Takahashi M, Nagahama Cohort Study Group, Kotoura Y, Yamada R, Ogawa O, Matsuda F Terao C, Terada N, Matsuo K, Kawaguchi T, Yoshimura K, Hayashi N, Shimizu M, Soga N, Takahashi M, Nagahama Cohort Study Group, Kotoura Y, Yamada R, Ogawa O, Matsuda F A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population. A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population. A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population. Journal of medical genetics, 51, 8, 530-536 Journal of medical genetics, 51, 8, 530-536 Journal of medical genetics, 51, 8, 530-536 2014/08 公開
Tanaka K, Terao C, Ohmura K, Takahashi M, Nakashima R, Imura Y, Yoshifuji H, Yukawa N, Usui T, Fujii T, Mimori T, Matsuda F Tanaka K, Terao C, Ohmura K, Takahashi M, Nakashima R, Imura Y, Yoshifuji H, Yukawa N, Usui T, Fujii T, Mimori T, Matsuda F Tanaka K, Terao C, Ohmura K, Takahashi M, Nakashima R, Imura Y, Yoshifuji H, Yukawa N, Usui T, Fujii T, Mimori T, Matsuda F Significant association between CYP3A5 polymorphism and blood concentration of tacrolimus in patients with connective tissue diseases. Significant association between CYP3A5 polymorphism and blood concentration of tacrolimus in patients with connective tissue diseases. Significant association between CYP3A5 polymorphism and blood concentration of tacrolimus in patients with connective tissue diseases. Journal of human genetics, 59, 2, 107-109 Journal of human genetics, 59, 2, 107-109 Journal of human genetics, 59, 2, 107-109 2014/02 公開
Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H, J-MICC Study Group Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H, J-MICC Study Group Wakai K, Matsuo K, Matsuda F, Yamada R, Takahashi M, Kawaguchi T, Yatabe Y, Ito H, Hosono S, Tajima K, Naito M, Morita E, Yin G, Sakamoto T, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Hamajima N, Tanaka H, J-MICC Study Group Genome-wide association study of genetic factors related to confectionery intake: potential roles of the ADIPOQ gene. Genome-wide association study of genetic factors related to confectionery intake: potential roles of the ADIPOQ gene. Genome-wide association study of genetic factors related to confectionery intake: potential roles of the ADIPOQ gene. Obesity (Silver Spring, Md.), 21, 11, 2413-2419 Obesity (Silver Spring, Md.), 21, 11, 2413-2419 Obesity (Silver Spring, Md.), 21, 11, 2413-2419 2013/11 公開
Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F Terao C, Yoshifuji H, Kimura A, Matsumura T, Ohmura K, Takahashi M, Shimizu M, Kawaguchi T, Chen Z, Naruse TK, Sato-Otsubo A, Ebana Y, Maejima Y, Kinoshita H, Murakami K, Kawabata D, Wada Y, Narita I, Tazaki J, Kawaguchi Y, Yamanaka H, Yurugi K, Miura Y, Maekawa T, Ogawa S, Komuro I, Nagai R, Yamada R, Tabara Y, Isobe M, Mimori T, Matsuda F Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. American journal of human genetics, 93, 2, 289-297 American journal of human genetics, 93, 2, 289-297 American journal of human genetics, 93, 2, 289-297 2013/08 公開
Kawaguchi T, Sumida Y, Umemura A, Matsuo K, Takahashi M, Takamura T, Yasui K, Saibara T, Hashimoto E, Kawanaka M, Watanabe S, Kawata S, Imai Y, Kokubo M, Shima T, Park H, Tanaka H, Tajima K, Yamada R, Matsuda F, Takeshi Okanoue, Japan Study Group of Nonalcoholic Fatty Liver Disease Kawaguchi T, Sumida Y, Umemura A, Matsuo K, Takahashi M, Takamura T, Yasui K, Saibara T, Hashimoto E, Kawanaka M, Watanabe S, Kawata S, Imai Y, Kokubo M, Shima T, Park H, Tanaka H, Tajima K, Yamada R, Matsuda F, Takeshi Okanoue, Japan Study Group of Nonalcoholic Fatty Liver Disease T. Kawaguchi; Y. Sumida; A. Umemura; K. Matsuo; M. Takahashi; T. Takamura; K. Yasui; T. Saibara; E. Hashimoto; M. Kawanaka; S. Watanabe; S. Kawata; Y. Imai; M. Kokubo; T. Shima; H. Park; H. Tanaka; K. Tajima; R. Yamada; F. Matsuda; T. Okanoue Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese. Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese. Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese PloS one, 7, 6, e38322 PloS one, 7, 6, e38322 PLoS ONE, 7, 6, e38322 2012/06/14 英語 公開
Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K Y. Okada; C. Terao; K. Ikari; Y. Kochi; K. Ohmura; A. Suzuki; T. Kawaguchi; E.A. Stahl; F.A.S. Kurreeman; N. Nishida; H. Ohmiya; K. Myouzen; M. Takahashi; T. Sawada; Y. Nishioka; M. Yukioka; T. Matsubara; S. Wakitani; R. Teshima; S. Tohma; K. Takasugi; K. Shimada; A. Murasawa; S. Honjo; K. Matsuo; H. Tanaka; K. Tajima; T. Suzuki; T. Iwamoto; Y. Kawamura; H. Tanii; Y. Okazaki; T. Sasaki; P.K. Gregersen; L. Padyukov; J. Worthington; K.A. Siminovitch; M. Lathrop; A. Taniguchi; A. Takahashi; K. Tokunaga; M. Kubo; Y. Nakamura; N. Kamatani; T. Mimori; R.M. Plenge; H. Yamanaka; S. Momohara; R. Yamada; F. Matsuda; K. Yamamoto Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population Nature genetics, 44, 5, 511-516 Nature genetics, 44, 5, 511-516 Nature Genetics, 44, 5, 511-516 2012/03 英語 公開
Meziani R, Yamada R, Takahashi M, Ohigashi K, Morinobu A, Terao C, Hiratani H, Ohmura K, Yamaguchi M, Nomura T, Vasilescu A, Kokubo M, Renault V, Hirosawa K, Ratanajaraya C, Heath S, Mimori T, Sakaguchi S, Lathrop M, Melchers I, Kumagai S, Matsuda F Meziani R, Yamada R, Takahashi M, Ohigashi K, Morinobu A, Terao C, Hiratani H, Ohmura K, Yamaguchi M, Nomura T, Vasilescu A, Kokubo M, Renault V, Hirosawa K, Ratanajaraya C, Heath S, Mimori T, Sakaguchi S, Lathrop M, Melchers I, Kumagai S, Matsuda F Meziani R, Yamada R, Takahashi M, Ohigashi K, Morinobu A, Terao C, Hiratani H, Ohmura K, Yamaguchi M, Nomura T, Vasilescu A, Kokubo M, Renault V, Hirosawa K, Ratanajaraya C, Heath S, Mimori T, Sakaguchi S, Lathrop M, Melchers I, Kumagai S, Matsuda F A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations. A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations. A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations. Modern rheumatology / the Japan Rheumatism Association, 22, 1, 52-58 Modern rheumatology / the Japan Rheumatism Association, 22, 1, 52-58 Modern rheumatology / the Japan Rheumatism Association, 22, 1, 52-58 2012/02 公開
Akagami M, Kawada K, Kubo H, Kawada M, Takahashi M, Kaganoi J, Kato S, Itami A, Shimada Y, Watanabe G, Sakai Y Akagami M, Kawada K, Kubo H, Kawada M, Takahashi M, Kaganoi J, Kato S, Itami A, Shimada Y, Watanabe G, Sakai Y M. Akagami; K. Kawada; H. Kubo; M. Kawada; M. Takahashi; J. Kaganoi; S. Kato; A. Itami; Y. Shimada; G. Watanabe; Y. Sakai Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells. Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells. Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells Annals of surgical oncology, 18, 13, 3868-3877 Annals of surgical oncology, 18, 13, 3868-3877 Annals of Surgical Oncology, 18, 13, 3868-3877 2011/12 英語 公開
Matsuse M, Takahashi M, Mitsutake N, Nishihara E, Hirokawa M, Kawaguchi T, Rogounovitch T, Saenko V, Bychkov A, Suzuki K, Matsuo K, Tajima K, Miyauchi A, Yamada R, Matsuda F, Yamashita S Matsuse M, Takahashi M, Mitsutake N, Nishihara E, Hirokawa M, Kawaguchi T, Rogounovitch T, Saenko V, Bychkov A, Suzuki K, Matsuo K, Tajima K, Miyauchi A, Yamada R, Matsuda F, Yamashita S Matsuse M, Takahashi M, Mitsutake N, Nishihara E, Hirokawa M, Kawaguchi T, Rogounovitch T, Saenko V, Bychkov A, Suzuki K, Matsuo K, Tajima K, Miyauchi A, Yamada R, Matsuda F, Yamashita S The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population. The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population. The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population. Journal of medical genetics, 48, 9, 645-648 Journal of medical genetics, 48, 9, 645-648 Journal of medical genetics, 48, 9, 645-648 2011/09 公開
Ratanajaraya C, Nishiyama H, Takahashi M, Kawaguchi T, Saito R, Mikami Y, Suyama M, Lathrop M, Yamada R, Ogawa O, Matsuda F Ratanajaraya C, Nishiyama H, Takahashi M, Kawaguchi T, Saito R, Mikami Y, Suyama M, Lathrop M, Yamada R, Ogawa O, Matsuda F C. Ratanajaraya; H. Nishiyama; M. Takahashi; T. Kawaguchi; R. Saito; Y. Mikami; M. Suyama; M. Lathrop; R. Yamada; O. Ogawa; F. Matsuda A polymorphism of the POLG2 gene is genetically associated with the invasiveness of urinary bladder cancer in Japanese males. A polymorphism of the POLG2 gene is genetically associated with the invasiveness of urinary bladder cancer in Japanese males. A polymorphism of the POLG2 gene is genetically associated with the invasiveness of urinary bladder cancer in Japanese males Journal of human genetics, 56, 8, 572-576 Journal of human genetics, 56, 8, 572-576 Journal of Human Genetics, 56, 8, 572-576 2011/08 英語 公開
Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y, Human Disease Genomics Working Group, RA Clinical and Genetic Study Consortium, Okada Y, Nakamura Y, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y, Human Disease Genomics Working Group, RA Clinical and Genetic Study Consortium, Okada Y, Nakamura Y, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y, Human Disease Genomics Working Group, RA Clinical and Genetic Study Consortium, Okada Y, Nakamura Y, Yamamoto K, Melchers I, Lathrop M, Mimori T, Matsuda F The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Human molecular genetics, 20, 13, 2680-2685 Human molecular genetics, 20, 13, 2680-2685 Human molecular genetics, 20, 13, 2680-2685 2011/07 公開
Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, Toda Y, Yamamoto N, Human Disease Genomics Working Group, Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium, Shinkura R, Shimizu M, Gut I, Heath S, Melchers I, Manabe T, Lathrop M, Mimori T, Yamada R, Matsuda F Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, Toda Y, Yamamoto N, Human Disease Genomics Working Group, Rheumatoid Arthritis (RA) Clinical and Genetic Study Consortium, Shinkura R, Shimizu M, Gut I, Heath S, Melchers I, Manabe T, Lathrop M, Mimori T, Yamada R, Matsuda F C. Terao; K. Ohmura; M. Katayama; M. Takahashi; M. Kokubo; G. Diop; Y. Toda; N. Yamamoto; R. Shinkura; M. Shimizu; I. Gut; S. Heath; I. Melchers; T. Manabe; M. Lathrop; T. Mimori; R. Yamada; F. Matsuda Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses. Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses. Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis-a genome-wide study combined with immunological analyses PloS one, 6, 6, e20457 PloS one, 6, 6, e20457 PLoS ONE, 6, 6, e20457 2011/06/03 英語 公開
Takahashi M, Saenko VA, Rogounovitch TI, Kawaguchi T, Drozd VM, Takigawa-Imamura H, Akulevich NM, Ratanajaraya C, Mitsutake N, Takamura N, Danilova LI, Lushchik ML, Demidchik YE, Heath S, Yamada R, Lathrop M, Matsuda F, Yamashita S Takahashi M, Saenko VA, Rogounovitch TI, Kawaguchi T, Drozd VM, Takigawa-Imamura H, Akulevich NM, Ratanajaraya C, Mitsutake N, Takamura N, Danilova LI, Lushchik ML, Demidchik YE, Heath S, Yamada R, Lathrop M, Matsuda F, Yamashita S M. Takahashi; V.A. Saenko; T.I. Rogounovitch; T. Kawaguchi; V.M. Drozd; H. Takigawa-Imamura; N.M. Akulevich; C. Ratanajaraya; N. Mitsutake; N. Takamura; L.I. Danilova; M.L. Lushchik; Y.E. Demidchik; S. Heath; R. Yamada; M. Lathrop; F. Matsuda; S. Yamashita The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl Human molecular genetics, 19, 12, 2516-2523 Human molecular genetics, 19, 12, 2516-2523 Human Molecular Genetics, 19, 12, 2516-2523 2010/06 英語 公開
Kono T, Shimoda M, Takahashi M, Matsumoto K, Yoshimoto T, Mizutani M, Tabata C, Okoshi K, Wada H, Kubo H Kono T, Shimoda M, Takahashi M, Matsumoto K, Yoshimoto T, Mizutani M, Tabata C, Okoshi K, Wada H, Kubo H T. Kono; M. Shimoda; M. Takahashi; K. Matsumoto; T. Yoshimoto; M. Mizutani; C. Tabata; K. Okoshi; H. Wada; H. Kubo Immunohistochemical detection of the lymphatic marker podoplanin in diverse types of human cancer cells using a novel antibody. Immunohistochemical detection of the lymphatic marker podoplanin in diverse types of human cancer cells using a novel antibody. Immunohistochemical detection of the lymphatic marker podoplanin in diverse types of human cancer cells using a novel antibody International journal of oncology, 31, 3, 501-508 International journal of oncology, 31, 3, 501-508 International Journal of Oncology, 31, 3, 501-508 2007/09 英語 公開
Tabata C, Tabata R, Kadokawa Y, Hisamori S, Takahashi M, Mishima M, Nakano T, Kubo H Tabata C, Tabata R, Kadokawa Y, Hisamori S, Takahashi M, Mishima M, Nakano T, Kubo H C. Tabata; R. Tabata; Y. Kadokawa; S. Hisamori; M. Takahashi; M. Mishima; T. Nakano; H. Kubo Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice. Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice. Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice Journal of immunology (Baltimore, Md. : 1950), 179, 1, 708-714 Journal of immunology (Baltimore, Md. : 1950), 179, 1, 708-714 Journal of Immunology, 179, 1, 708-714 2007/07 英語 公開
Yoshimoto T, Takahashi M, Nagayama S, Watanabe G, Shimada Y, Sakasi Y, Kubo H Yoshimoto T, Takahashi M, Nagayama S, Watanabe G, Shimada Y, Sakasi Y, Kubo H T. Yoshimoto; M. Takahashi; S. Nagayama; G. Watanabe; Y. Shimada; Y. Sakasi; H. Kubo RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay. RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay. RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay Biochemical and biophysical research communications, 359, 2, 258-262 Biochemical and biophysical research communications, 359, 2, 258-262 Biochemical and Biophysical Research Communications, 359, 2, 258-262 2007/07 英語 公開
Takahashi M, Yoshimoto T, Shimoda M, Kono T, Koizumi M, Yazumi S, Shimada Y, Doi R, Chiba T, Kubo H Takahashi M, Yoshimoto T, Shimoda M, Kono T, Koizumi M, Yazumi S, Shimada Y, Doi R, Chiba T, Kubo H M. Takahashi; T. Yoshimoto; M. Shimoda; T. Kono; M. Koizumi; S. Yazumi; Y. Shimada; R. Doi; T. Chiba; H. Kubo Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells. Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells. Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells Neoplasia (New York, N.Y.), 8, 12, 1003-1010 Neoplasia (New York, N.Y.), 8, 12, 1003-1010 Neoplasia, 8, 12, 1003-1010 2006/12 英語 公開
Tabata C, Kadokawa Y, Tabata R, Takahashi M, Okoshi K, Sakai Y, Mishima M, Kubo H Tabata C, Kadokawa Y, Tabata R, Takahashi M, Okoshi K, Sakai Y, Mishima M, Kubo H C. Tabata; Y. Kadokawa; R. Tabata; M. Takahashi; K. Okoshi; Y. Sakai; M. Mishima; H. Kubo All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis. All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis. All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis American journal of respiratory and critical care medicine, 174, 12, 1352-1360 American journal of respiratory and critical care medicine, 174, 12, 1352-1360 American Journal of Respiratory and Critical Care Medicine, 174, 12, 1352-1360 2006/12 英語 公開
Shimoda M, Takahashi M, Yoshimoto T, Kono T, Ikai I, Kubo H Shimoda M, Takahashi M, Yoshimoto T, Kono T, Ikai I, Kubo H M. Shimoda; M. Takahashi; T. Yoshimoto; T. Kono; I. Ikai; H. Kubo A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma. A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma. A homeobox protein, Prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma Clinical cancer research : an official journal of the American Association for Cancer Research, 12, 20 Pt 1, 6005-6011 Clinical cancer research : an official journal of the American Association for Cancer Research, 12, 20 Pt 1, 6005-6011 Clinical Cancer Research, 12, 20 Pt 1, 6005-6011 2006/10 英語 公開
Kono T, Kubo H, Shimazu C, Ueda Y, Takahashi M, Yanagi K, Fujita N, Tsuruo T, Wada H, Yamashita JK Kono T, Kubo H, Shimazu C, Ueda Y, Takahashi M, Yanagi K, Fujita N, Tsuruo T, Wada H, Yamashita JK T. Kono; H. Kubo; C. Shimazu; Y. Ueda; M. Takahashi; K. Yanagi; N. Fujita; T. Tsuruo; H. Wada; J.K. Yamashita Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells. Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells. Differentiation of lymphatic endothelial cells from embryonic stem cells on OP9 stromal cells Arteriosclerosis, thrombosis, and vascular biology, 26, 9, 2070-2076 Arteriosclerosis, thrombosis, and vascular biology, 26, 9, 2070-2076 Arteriosclerosis, Thrombosis, and Vascular Biology, 26, 9, 2070-2076 2006/09 英語 公開
Takahashi M, Nakamura Y, Obama K, Furukawa Y Takahashi M, Nakamura Y, Obama K, Furukawa Y Takahashi M, Nakamura Y, Obama K, Furukawa Y Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer. International journal of oncology, 27, 6, 1483-1487 International journal of oncology, 27, 6, 1483-1487 International journal of oncology, 27, 6, 1483-1487 2005/12 公開
Takahashi M, Lin YM, Nakamura Y, Furukawa Y Takahashi M, Lin YM, Nakamura Y, Furukawa Y M. Takahashi; Y.-M. Lin; Y. Nakamura; Y. Furukawa Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer Oncogene, 23, 57, 9289-9294 Oncogene, 23, 57, 9289-9294 Oncogene, 23, 57, 9289-9294 2004/12 英語 公開
Takahashi M, Yoshimoto T, Kubo H Takahashi M, Yoshimoto T, Kubo H M. Takahashi; T. Yoshimoto; H. Kubo Molecular mechanisms of lymphangiogenesis. Molecular mechanisms of lymphangiogenesis. Molecular mechanisms of lymphangiogenesis International journal of hematology, 80, 1, 29-34 International journal of hematology, 80, 1, 29-34 International Journal of Hematology, 80, 1, 29-34 2004/07 英語 公開
Kroes, H.Y., Takahashi, M., Zijlstra, R.J., Baert, J.A.L.L., Kooi, K.A., Hofstra, R.M.W., and van Essen, A.J. Kroes, H.Y., Takahashi, M., Zijlstra, R.J., Baert, J.A.L.L., Kooi, K.A., Hofstra, R.M.W., and van Essen, A.J. Kroes, H.Y., Takahashi, M., Zijlstra, R.J., Baert, J.A.L.L., Kooi, K.A., Hofstra, R.M.W., and van Essen, A.J. Two cases of the caudal duplication anomaly including a discordant monozygotic twin. Two cases of the caudal duplication anomaly including a discordant monozygotic twin. Two cases of the caudal duplication anomaly including a discordant monozygotic twin. Am J Med Genet, 112, 4, 390-393 Am J Med Genet, 112, 4, 390-393 Am J Med Genet, 112, 4, 390-393 2002/11 公開
Takahashi M, Fujita M, Furukawa Y, Hamamoto R, Shimokawa T, Miwa N, Ogawa M, Nakamura Y Takahashi M, Fujita M, Furukawa Y, Hamamoto R, Shimokawa T, Miwa N, Ogawa M, Nakamura Y Takahashi M, Fujita M, Furukawa Y, Hamamoto R, Shimokawa T, Miwa N, Ogawa M, Nakamura Y Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. Cancer research, 62, 20, 5651-5656 Cancer research, 62, 20, 5651-5656 Cancer research, 62, 20, 5651-5656 2002/10 公開
Takahashi M, Tsunoda T, Seiki M, Nakamura Y, Furukawa Y Takahashi M, Tsunoda T, Seiki M, Nakamura Y, Furukawa Y M. Takahashi; T. Tsunoda; M. Seiki; Y. Nakamura; Y. Furukawa Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Identification of membrane-type matrix metalloproteinase-1 as a target of the β-catenin/Tcf4 complex in human colorectal cancers Oncogene, 21, 38, 5861-5867 Oncogene, 21, 38, 5861-5867 Oncogene, 21, 38, 5861-5867 2002/08 英語 公開
Leonard, N., Chagger, R., Jones, C., Takahashi, M., Nikitopoulou, A., and Lakhani, S.R. Leonard, N., Chagger, R., Jones, C., Takahashi, M., Nikitopoulou, A., and Lakhani, S.R. Leonard, N., Chagger, R., Jones, C., Takahashi, M., Nikitopoulou, A., and Lakhani, S.R. Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours J Clin Pathol, 54, 689-692 J Clin Pathol, 54, 689-692 J Clin Pathol, 54, 689-692 2001/09 公開
Furukawa, Y., Kawasoe, T., Daigo, Y., Nishiwaki, T., Ishiguro, H., Takahashi, M., Kitayama, J., and Nakamura, Y Furukawa, Y., Kawasoe, T., Daigo, Y., Nishiwaki, T., Ishiguro, H., Takahashi, M., Kitayama, J., and Nakamura, Y Y. Furukawa; T. Kawasoe; Y. Daigo; T. Nishiwaki; H. Ishiguro; M. Takahashi; J. Kitayama; Y. Nakamura Isolation of a novel human gene, ARHGAP9, encoding a Rho-GTPase activating protein. Isolation of a novel human gene, ARHGAP9, encoding a Rho-GTPase activating protein. Isolation of a novel human gene, ARHGAP9, encoding a Rho-GTPase activating protein Biochem Biophys Res Commun., 284, 3, 643-649 Biochem Biophys Res Commun., 284, 3, 643-649 Biochemical and Biophysical Research Communications, 284, 3, 643-649 2001/06 英語 公開
Bignell, G.R., Warren, W., Seal, S., Takahashi, M., Rapley E., Barfoot, R., Gree, H., Brown, C., Biggs, P.J., Lakhani, S.R., Jones, C., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, G., Schrander-Stumpel, C., Beemer, F.A, van den Ouweland, A., Halley, D., Delpech, B., Cleveland, M.G., Leigh, I., Leisti, J., Rasmussen, S., Wallace, M.R., Fenske, C., Banerjee, P., Oiso, N., Chaggar, R., Merrett, S., Leonard, N., Huber, M., Hohl, D., Chapman, P., Burn, J., Swift, S., Smith, A., Ashworth, A., and Stratton, M.R. Bignell, G.R., Warren, W., Seal, S., Takahashi, M., Rapley E., Barfoot, R., Gree, H., Brown, C., Biggs, P.J., Lakhani, S.R., Jones, C., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, G., Schrander-Stumpel, C., Beemer, F.A, van den Ouweland, A., Halley, D., Delpech, B., Cleveland, M.G., Leigh, I., Leisti, J., Rasmussen, S., Wallace, M.R., Fenske, C., Banerjee, P., Oiso, N., Chaggar, R., Merrett, S., Leonard, N., Huber, M., Hohl, D., Chapman, P., Burn, J., Swift, S., Smith, A., Ashworth, A., and Stratton, M.R. Bignell, G.R., Warren, W., Seal, S., Takahashi, M., Rapley E., Barfoot, R., Gree, H., Brown, C., Biggs, P.J., Lakhani, S.R., Jones, C., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, G., Schrander-Stumpel, C., Beemer, F.A, van den Ouweland, A., Halley, D., Delpech, B., Cleveland, M.G., Leigh, I., Leisti, J., Rasmussen, S., Wallace, M.R., Fenske, C., Banerjee, P., Oiso, N., Chaggar, R., Merrett, S., Leonard, N., Huber, M., Hohl, D., Chapman, P., Burn, J., Swift, S., Smith, A., Ashworth, A., and Stratton, M.R. Identification of the familial cylindromatosis tumour suppressor gene Identification of the familial cylindromatosis tumour suppressor gene Identification of the familial cylindromatosis tumour suppressor gene Nature Genet, 25, 162-165 Nature Genet, 25, 162-165 Nature Genet, 25, 162-165 2000/06 研究論文(学術雑誌) 公開
Takahashi, M., Rapley, E., Biggs, P.J., Lakhani S.R., Cooke, D., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, D.G., Schrander-Stumpel, C., Beemer, F.A., van Vloten, W.A., Breuning, M.H., van den Ouweland, A., Halley, D., Delpech, B. Takahashi, M., Rapley, E., Biggs, P.J., Lakhani S.R., Cooke, D., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, D.G., Schrander-Stumpel, C., Beemer, F.A., van Vloten, W.A., Breuning, M.H., van den Ouweland, A., Halley, D., Delpech, B. Takahashi, M., Rapley, E., Biggs, P.J., Lakhani S.R., Cooke, D., Hansen, J., Blair, E., Hofmann, B., Siebert, R., Turner, G., Evans, D.G., Schrander-Stumpel, C., Beemer, F.A., van Vloten, W.A., Breuning, M.H., van den Ouweland, A., Halley, D., Delpech, B. Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13 Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13 Linkage and LOH studies in 19 cylindromatosis families show no evidence of genetic heterogeneity and refine the CYLD locus on chromosome 16q12-q13 Hum Genet, 106, 58-65 Hum Genet, 106, 58-65 Hum Genet, 106, 58-65 2000/01 公開
Wakai,K., Matsuo,K., Matsuda,F., Yamada,R., Takahashi,M., et al. Wakai,K., Matsuo,K., Matsuda,F., Yamada,R., Takahashi,M., et al. Genome-wide association study of the genetic factors related to confectionery intake: potential roles of the ADIPOQ gene Genome-wide association study of the genetic factors related to confectionery intake: potential roles of the ADIPOQ gene Obesity (Silver Spring). doi: 10.1002 Obesity (Silver Spring). doi: 10.1002 2012/02/14 英語 公開
Matsuse, M., Takahashi, M., Mitsutake, N., Nishihara, E., et al. Matsuse, M., Takahashi, M., Mitsutake, N., Nishihara, E., et al. The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population. J Med Gen, 2011 The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population. J Med Gen, 2011 2011 英語 公開
Terao, C., Yamada, R., Ohmura, K., Takahashi, M., et al. Terao, C., Yamada, R., Ohmura, K., Takahashi, M., et al. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet. 2011 Jul 1;20(13):2680-5. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet. 2011 Jul 1;20(13):2680-5. 2011 英語 公開
Meziani, R., Yamada, R., Takahashi, M., Ohigashi, K., et al. Meziani, R., Yamada, R., Takahashi, M., Ohigashi, K., et al. A Trans-ethnic genetic study of Rheumatoid Arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations. Mod Rheumatol. 2011 May 24. A Trans-ethnic genetic study of Rheumatoid Arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations. Mod Rheumatol. 2011 May 24. 2011 英語 公開
M. Takahashi; M. Fujita; Y. Furukawa; R. Hamamoto; T. Shimokawa; N. Miwa; M. Ogawa; Y. Nakamura M. Takahashi; M. Fujita; Y. Furukawa; R. Hamamoto; T. Shimokawa; N. Miwa; M. Ogawa; Y. Nakamura Isolation of a novel human gene, APCDD1, as a direct target of the β-catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis Isolation of a novel human gene, APCDD1, as a direct target of the β-catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis Cancer Research, 62, 20, 5651-5656 , 62, 20, 5651-5656 Cancer Research, 62, 20, 5651-5656 2002 英語 公開

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タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
若手研究(B) 代表 ES細胞からのリンパ管内皮細胞分化と腫瘍リンパ管特異的な標的分子の探索 2004/__/__〜2005/__/__
基盤研究(C) 代表 新規癌抑制遺伝子PROX1の機能解析と臨床への応用 Characterization of PROX1, a novel tumor suppressor gene 2006〜2007/__/__
若手研究(B) 代表 チェルノブイリコホートの全ゲノム解析による放射線誘発甲状腺がん感受性遺伝子の同定 Identification of genetic determinants for radiation-induced thyroid cancer using the Chernobyl prospective cohort 2009〜2010
基盤研究(C) 代表 日本人におけるEGFR遺伝子変異型肺がんリスクに関連する遺伝子の解明 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 日本人におけるEGFR遺伝子変異型肺がんリスクに関連する遺伝子の解明 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(C) 代表 日本人におけるEGFR遺伝子変異型肺がんリスクに関連する遺伝子の解明 (平成30年度分) 2018/04/01〜2019/03/31
外部資金:競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
財団法人藤原記念財団奨励金 高橋めい子 チェルノブイリコホートの全ゲノム解析による放射線誘発甲状腺がん感受性遺伝子の同定 Identification of genetic determinants for radiation-induced thyroid cancer using the Chernobyl prospective cohort 2010〜2011
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
ゲノムコホート研究(LIMS) Genome Cohort Study 前期集中 医学研究科 2015/04〜2016/03
ゲノムコホート研究(LIMS) Genome Cohort Study 前期集中 医学研究科 2016/04〜2017/03
ゲノムコホート研究 Genomic medicine and comprehensive human bioscience 前期 工学研究科 2017/04〜2018/03
ゲノムコホート研究(LIMS) Genome Cohort Study (LIMS) 前期集中 医学研究科 2017/04〜2018/03
ゲノムコホート研究 Genomic medicine and comprehensive human bioscience 前期 工学研究科 2018/04〜2019/03
ゲノムコホート研究(LIMS) Genome Cohort Study (LIMS) 前期集中 医学研究科 2018/04〜2019/03
ゲノムコホート研究(LIMS) Genome Cohort Study (LIMS) 前期集中 医学研究科 2019/04〜2020/03
海外での滞在歴
滞在機関名 部署 研究テーマ 国名 期間
Institute of Cancer Research Cancer Genetics Identification of the familial cylindromatosis tumour-suppressor gene UK 1996〜2000