橋田 充

最終更新日時: 2016/07/28 17:14:40

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氏名(漢字/フリガナ/アルファベット表記)
橋田 充/ハシダ ミツル/Hashida, Mitsuru
所属部署・職名(部局/所属/講座等/職名)
高等研究院/物質-細胞統合システム拠点/特定教授
学部兼担
部局 所属 講座等 職名
薬学部
学内兼務
部局 所属 講座等 職名
物質-細胞統合システム拠点 連携主任研究者
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8501 京都市左京区吉田下阿達町46-29 京都大学大学院薬学研究科 薬品動態制御学分野 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan
所属学会(国内)
学会名(日本語) 学会名(英語)
日本薬学会 The Pharmaceutical Society of Japan (PSJ)
日本薬剤学会 The Academy of Pharmaceutical Science and Technology, Japan (APSTJ)
日本薬物動態学会 The Japanese Society for the Study of Xenobiotics (JSSX)
日本DDS学会 The Japan Society of Drug Delivery System (DDS)
日本癌学会 The Japanese Cancer Association (JCA)
日本高分子学会 The Society of Polymer Science, Japan (SPSJ)
日本癌治療学会 The Japan Society of Clinical Oncology (JSCO)
所属学会(海外)
学会名(英語) 国名
Controlled Release Society (CRS) アメリカ
International Pharmaceutical Federation (FIP) オランダ
American Association of Pharmaceutical Scientists (AAPS) アメリカ
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
薬学修士 京都大学
薬学博士 京都大学
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
京都大学 大学院薬学研究科博士課程薬学専攻 修了
京都大学 大学院薬学研究科修士課程薬学専攻 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
京都大学 薬学部薬学科 卒業
出身高等学校
高等学校名 ふりがな
大阪教育大学附属高等学校天王寺校舎 おおさかきょういくだいがくふぞくこうとうがっこうてんのうじこうしゃ
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
1979/10/01〜1980/03/31 カンサス大学薬学部 School of Pharmacy, The University of Kansas 研究員 Postdoctoral Research Associate
1980/04/01〜1983/04/30 京都大学薬学部 Faculty of Pharmaceutical Sciences, Kyoto University 助手 Assistant Professor
1983/05/01〜1992/03/31 京都大学薬学部 Faculty of Pharmaceutical Sciences, Kyoto University 助教授 Associate Professor
1992/04/01〜1997/03/31 京都大学薬学部 Faculty of Pharmaceutical Sciences, Kyoto University 教授 Professor
1997/04/01〜 京都大学大学院薬学研究科 Graduate School of Pharmaceutical Sciences, Kyoto University 教授 Professor
2002/05/01〜2006/04/01 京都大学大学院薬学研究科 Graduate School of Pharmaceutical Sciences, Kyoto University 研究科長・薬学部長 Dean
2008/01/01〜 京都大学物質-細胞統合システム拠点 (iCeMS) Institute for Integrated Cell-Material Sciences, Kyoto University 教授 Principal Investigator
使用言語
言語名
英語
個人ホームページ
URL
http://dds.pharm.kyoto-u.ac.jp/wp_home/
researchmap URL
https://researchmap.jp/read0013263
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Development of a support vector machine-based system to predict whether a compound is a substrate of a given drug transporter using its chemical structure Development of a support vector machine-based system to predict whether a compound is a substrate of a given drug transporter using its chemical structure Development of a support vector machine-based system to predict whether a compound is a substrate of a given drug transporter using its chemical structure Journal of Pharmaceutical Sciences, 105, 7, 2222-2230 Journal of Pharmaceutical Sciences, 105, 7, 2222-2230 Journal of Pharmaceutical Sciences, 105, 7, 2222-2230 2016/07 英語 研究論文(学術雑誌) 公開
Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K Tumor growth suppression by the combination of nanobubbles and ultrasound Tumor growth suppression by the combination of nanobubbles and ultrasound Tumor growth suppression by the combination of nanobubbles and ultrasound Cancer Science, 107, 3, 217-223 Cancer Science, 107, 3, 217-223 Cancer Science, 107, 3, 217-223 2016/03 英語 研究論文(学術雑誌) 公開
Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Optimization of renal transfection using a renal suction-mediated transfection method in mice Optimization of renal transfection using a renal suction-mediated transfection method in mice Optimization of renal transfection using a renal suction-mediated transfection method in mice Journal of Drug Targeting, 24, 5, 450-456 Journal of Drug Targeting, 24, 5, 450-456 Journal of Drug Targeting, 24, 5, 450-456 2016 英語 研究論文(学術雑誌) 公開
Baba H, Takahara JI, Yamashita F, Hashida M Baba H, Takahara JI, Yamashita F, Hashida M Baba H, Takahara JI, Yamashita F, Hashida M Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Pharmaceutical research Pharmaceutical research Pharmaceutical research 2015/06 英語 公開
Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. International journal of pharmaceutics, 487, 1-2, 64-71 International journal of pharmaceutics, 487, 1-2, 64-71 International journal of pharmaceutics, 487, 1-2, 64-71 2015/06 英語 公開
Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Acta biomaterialia, 19, 112-118 Acta biomaterialia, 19, 112-118 Acta biomaterialia, 19, 112-118 2015/06 英語 公開
Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Journal of drug targeting, 23, 5, 427-435 Journal of drug targeting, 23, 5, 427-435 Journal of drug targeting, 23, 5, 427-435 2015/06 英語 公開
Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Carbohydrate research, 405, 78-86 Carbohydrate research, 405, 78-86 Carbohydrate research, 405, 78-86 2015/03 英語 公開
Shimizu K, Araki H, Sakata K, Tonomura W, Hashida M, Konishi S Shimizu K, Araki H, Sakata K, Tonomura W, Hashida M, Konishi S Shimizu K, Araki H, Sakata K, Tonomura W, Hashida M, Konishi S Microfluidic devices for construction of contractile skeletal muscle microtissues. Microfluidic devices for construction of contractile skeletal muscle microtissues. Microfluidic devices for construction of contractile skeletal muscle microtissues. Journal of bioscience and bioengineering, 119, 2, 212-216 Journal of bioscience and bioengineering, 119, 2, 212-216 Journal of bioscience and bioengineering, 119, 2, 212-216 2015/02 英語 公開
Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. The Journal of toxicological sciences, 40, 2, 277-294 The Journal of toxicological sciences, 40, 2, 277-294 The Journal of toxicological sciences, 40, 2, 277-294 2015 英語 公開
Babazada H, Yamashita F, Hashida M Babazada H, Yamashita F, Hashida M Babazada H, Yamashita F, Hashida M Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 2014/11 英語 公開
Babazada H, Yamashita F, Yanamoto S, Hashida M Babazada H, Yamashita F, Yanamoto S, Hashida M Babazada H, Yamashita F, Yanamoto S, Hashida M Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 2014/11 英語 公開
Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. International journal of pharmaceutics, 475, 1-2, 401-407 International journal of pharmaceutics, 475, 1-2, 401-407 International journal of pharmaceutics, 475, 1-2, 401-407 2014/11 英語 公開
Nakanishi H, Higuchi Y, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Yamashita F, Hashida M Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Journal of biotechnology, 186, 139-147 Journal of biotechnology, 186, 139-147 Journal of biotechnology, 186, 139-147 2014/09 英語 公開
Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. International journal of pharmaceutics, 471, 214-223 International journal of pharmaceutics, 471, 214-223 International journal of pharmaceutics, 471, 214-223 2014/08 英語 公開
Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 2014/06 英語 公開
Murakami T, Nakatsuji H, Morone N, Heuser JE, Ishidate F, Hashida M, Imahori H Murakami T, Nakatsuji H, Morone N, Heuser JE, Ishidate F, Hashida M, Imahori H Murakami T, Nakatsuji H, Morone N, Heuser JE, Ishidate F, Hashida M, Imahori H Mesoscopic Metal Nanoparticles Doubly Functionalized with Natural and Engineered Lipidic Dispersants for Therapeutics. Mesoscopic Metal Nanoparticles Doubly Functionalized with Natural and Engineered Lipidic Dispersants for Therapeutics. Mesoscopic Metal Nanoparticles Doubly Functionalized with Natural and Engineered Lipidic Dispersants for Therapeutics. ACS nano, 8, 7, 7370-7376 ACS nano, 8, 7, 7370-7376 ACS nano, 8, 7, 7370-7376 2014/06 英語 公開
Kawakami S, Hashida M Kawakami S, Hashida M Kawakami S, Hashida M Glycosylation-mediated targeting of carriers. Glycosylation-mediated targeting of carriers. Glycosylation-mediated targeting of carriers. Journal of controlled release : official journal of the Controlled Release Society, 190, 542-555 Journal of controlled release : official journal of the Controlled Release Society, 190, 542-555 Journal of controlled release : official journal of the Controlled Release Society, 190, 542-555 2014/06 英語 公開
Unga J, Hashida M Unga J, Hashida M Unga J, Hashida M Ultrasound induced cancer immunotherapy. Ultrasound induced cancer immunotherapy. Ultrasound induced cancer immunotherapy. Advanced drug delivery reviews, 72C, 144-153 Advanced drug delivery reviews, 72C, 144-153 Advanced drug delivery reviews, 72C, 144-153 2014/06 英語 公開
Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Journal of drug targeting, 22, 439-449 Journal of drug targeting, 22, 439-449 Journal of drug targeting, 22, 439-449 2014/06 英語 公開
Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Anti-tumor effect of NF-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Anti-tumor effect of NF-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Anti-tumor effect of NF-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Cancer science, 105, 8, 1049-1055 Cancer science, 105, 8, 1049-1055 Cancer science, 105, 8, 1049-1055 2014/05 英語 公開
Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Journal of drug targeting, 22, 8, 732-738 Journal of drug targeting, 22, 8, 732-738 Journal of drug targeting, 22, 8, 732-738 2014/05 英語 公開
Katsumi H, Nishikawa M, Nishiyama K, Hirosaki R, Nagamine N, Okamoto H, Mizuguchi H, Kusamori K, Yasui H, Yamashita F, Hashida M, Sakane T, Yamamoto A Katsumi H, Nishikawa M, Nishiyama K, Hirosaki R, Nagamine N, Okamoto H, Mizuguchi H, Kusamori K, Yasui H, Yamashita F, Hashida M, Sakane T, Yamamoto A Katsumi H, Nishikawa M, Nishiyama K, Hirosaki R, Nagamine N, Okamoto H, Mizuguchi H, Kusamori K, Yasui H, Yamashita F, Hashida M, Sakane T, Yamamoto A Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice. Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice. Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice. Free radical biology & medicine, 69, 318-323 Free radical biology & medicine, 69, 318-323 Free radical biology & medicine, 69, 318-323 2014/04 英語 公開
Ukawa M, Akita H, Hayashi Y, Ishiba R, Tange K, Arai M, Kubo K, Higuchi Y, Shimizu K, Konishi S, Hashida M, Harashima H Ukawa M, Akita H, Hayashi Y, Ishiba R, Tange K, Arai M, Kubo K, Higuchi Y, Shimizu K, Konishi S, Hashida M, Harashima H Ukawa M, Akita H, Hayashi Y, Ishiba R, Tange K, Arai M, Kubo K, Higuchi Y, Shimizu K, Konishi S, Hashida M, Harashima H Neutralized Nanoparticle Composed of SS-Cleavable and pH-Activated Lipid-Like Material as a Long-Lasting and Liver-Specific Gene Delivery System. Neutralized Nanoparticle Composed of SS-Cleavable and pH-Activated Lipid-Like Material as a Long-Lasting and Liver-Specific Gene Delivery System. Neutralized Nanoparticle Composed of SS-Cleavable and pH-Activated Lipid-Like Material as a Long-Lasting and Liver-Specific Gene Delivery System. Advanced healthcare materials, 3, 8, 1222-1229 Advanced healthcare materials, 3, 8, 1222-1229 Advanced healthcare materials, 3, 8, 1222-1229 2014/03 英語 公開
Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice. Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice. Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice. Journal of controlled release : official journal of the Controlled Release Society, 176, 24-34 Journal of controlled release : official journal of the Controlled Release Society, 176, 24-34 Journal of controlled release : official journal of the Controlled Release Society, 176, 24-34 2014/02 英語 公開
Hashida Y, Tanaka H, Zhou S, Kawakami S, Yamashita F, Murakami T, Umeyama T, Imahori H, Hashida M Hashida Y, Tanaka H, Zhou S, Kawakami S, Yamashita F, Murakami T, Umeyama T, Imahori H, Hashida M Hashida Y, Tanaka H, Zhou S, Kawakami S, Yamashita F, Murakami T, Umeyama T, Imahori H, Hashida M Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite. Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite. Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite. Journal of controlled release : official journal of the Controlled Release Society, 173, 59-66 Journal of controlled release : official journal of the Controlled Release Society, 173, 59-66 Journal of controlled release : official journal of the Controlled Release Society, 173, 59-66 2014/01 英語 公開
Shimizu K, Zhang G, Kawakami S, Taniguchi Y, Hayashi K, Hashida M, Konishi S Shimizu K, Zhang G, Kawakami S, Taniguchi Y, Hayashi K, Hashida M, Konishi S Shimizu K, Zhang G, Kawakami S, Taniguchi Y, Hayashi K, Hashida M, Konishi S Liver suction-mediated transfection in mice using a pressure-controlled computer system. Liver suction-mediated transfection in mice using a pressure-controlled computer system. Liver suction-mediated transfection in mice using a pressure-controlled computer system. Biological & pharmaceutical bulletin, 37, 4, 569-575 Biological & pharmaceutical bulletin, 37, 4, 569-575 Biological & pharmaceutical bulletin, 37, 4, 569-575 2014 英語 公開
Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Biological & pharmaceutical bulletin, 37, 4, 648-653 Biological & pharmaceutical bulletin, 37, 4, 648-653 Biological & pharmaceutical bulletin, 37, 4, 648-653 2014 英語 公開
Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. Biological & pharmaceutical bulletin, 37, 137-144 Biological & pharmaceutical bulletin, 37, 137-144 Biological & pharmaceutical bulletin, 37, 137-144 2014 英語 公開
Mathew S, Murakami T, Nakatsuji H, Okamoto H, Morone N, Heuser JE, Hashida M, Imahori H Mathew S, Murakami T, Nakatsuji H, Okamoto H, Morone N, Heuser JE, Hashida M, Imahori H Mathew S, Murakami T, Nakatsuji H, Okamoto H, Morone N, Heuser JE, Hashida M, Imahori H Exclusive photothermal heat generation by a gadolinium bis(naphthalocyanine) complex and inclusion into modified high-density lipoprotein nanocarriers for therapeutic applications. Exclusive photothermal heat generation by a gadolinium bis(naphthalocyanine) complex and inclusion into modified high-density lipoprotein nanocarriers for therapeutic applications. Exclusive photothermal heat generation by a gadolinium bis(naphthalocyanine) complex and inclusion into modified high-density lipoprotein nanocarriers for therapeutic applications. ACS nano, 7, 8908-8916 ACS nano, 7, 8908-8916 ACS nano, 7, 8908-8916 2013/10 英語 公開
Yoshida S, Yamashita F, Ose A, Maeda K, Sugiyama Y, Hashida M Yoshida S, Yamashita F, Ose A, Maeda K, Sugiyama Y, Hashida M Yoshida S, Yamashita F, Ose A, Maeda K, Sugiyama Y, Hashida M Automated extraction of information on chemical-P-glycoprotein interactions from the literature. Automated extraction of information on chemical-P-glycoprotein interactions from the literature. Automated extraction of information on chemical-P-glycoprotein interactions from the literature. Journal of chemical information and modeling, 53, 2506-2510 Journal of chemical information and modeling, 53, 2506-2510 Journal of chemical information and modeling, 53, 2506-2510 2013/10 英語 公開
Ikemura M, Nishikawa M, Kusamori K, Fukuoka M, Yamashita F, Hashida M Ikemura M, Nishikawa M, Kusamori K, Fukuoka M, Yamashita F, Hashida M Ikemura M, Nishikawa M, Kusamori K, Fukuoka M, Yamashita F, Hashida M Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice. Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice. Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice. Journal of controlled release : official journal of the Controlled Release Society, 170, 191-197 Journal of controlled release : official journal of the Controlled Release Society, 170, 191-197 Journal of controlled release : official journal of the Controlled Release Society, 170, 191-197 2013/09 英語 公開
Yamashita F, Hashida M Yamashita F, Hashida M Yamashita F, Hashida M Pharmacokinetic considerations for targeted drug delivery. Pharmacokinetic considerations for targeted drug delivery. Pharmacokinetic considerations for targeted drug delivery. Advanced drug delivery reviews, 65, 139-147 Advanced drug delivery reviews, 65, 139-147 Advanced drug delivery reviews, 65, 139-147 2013/01 英語 公開
Takafuji Y, Higuchi Y, Muro A, Oshiro K, Kawakami S, Yamashita F, Hashida M Takafuji Y, Higuchi Y, Muro A, Oshiro K, Kawakami S, Yamashita F, Hashida M Takafuji Y, Higuchi Y, Muro A, Oshiro K, Kawakami S, Yamashita F, Hashida M Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids. Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids. Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids. Biological & pharmaceutical bulletin, 36, 1731-1738 Biological & pharmaceutical bulletin, 36, 1731-1738 Biological & pharmaceutical bulletin, 36, 1731-1738 2013 英語 公開
Yamashita F, Sasa Y, Yoshida S, Hisaka A, Asai Y, Kitano H, Hashida M, Suzuki H Yamashita F, Sasa Y, Yoshida S, Hisaka A, Asai Y, Kitano H, Hashida M, Suzuki H Yamashita F, Sasa Y, Yoshida S, Hisaka A, Asai Y, Kitano H, Hashida M, Suzuki H Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data. Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data. Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data. PloS one, 8, e70330 PloS one, 8, e70330 PloS one, 8, e70330 2013 英語 公開
Murakami T, Nakatsuji H, Inada M, Matoba Y, Umeyama T, Tsujimoto M, Isoda S, Hashida M, Imahori H Murakami T, Nakatsuji H, Inada M, Matoba Y, Umeyama T, Tsujimoto M, Isoda S, Hashida M, Imahori H Murakami T, Nakatsuji H, Inada M, Matoba Y, Umeyama T, Tsujimoto M, Isoda S, Hashida M, Imahori H Photodynamic and photothermal effects of semiconducting and metallic-enriched single-walled carbon nanotubes. Photodynamic and photothermal effects of semiconducting and metallic-enriched single-walled carbon nanotubes. Photodynamic and photothermal effects of semiconducting and metallic-enriched single-walled carbon nanotubes. Journal of the American Chemical Society, 134, 17862-17865 Journal of the American Chemical Society, 134, 17862-17865 Journal of the American Chemical Society, 134, 17862-17865 2012/10 英語 公開
Kasai H, Murakami T, Ikuta Y, Koseki Y, Baba K, Oikawa H, Nakanishi H, Okada M, Shoji M, Ueda M, Imahori H, Hashida M Kasai H, Murakami T, Ikuta Y, Koseki Y, Baba K, Oikawa H, Nakanishi H, Okada M, Shoji M, Ueda M, Imahori H, Hashida M Kasai H, Murakami T, Ikuta Y, Koseki Y, Baba K, Oikawa H, Nakanishi H, Okada M, Shoji M, Ueda M, Imahori H, Hashida M Creation of pure nanodrugs and their anticancer properties. Creation of pure nanodrugs and their anticancer properties. Creation of pure nanodrugs and their anticancer properties. Angewandte Chemie (International ed. in English), 51, 10315-10318 Angewandte Chemie (International ed. in English), 51, 10315-10318 Angewandte Chemie (International ed. in English), 51, 10315-10318 2012/10 英語 公開
Hashida Y, Umeyama T, Mihara J, Imahori H, Tsujimoto M, Isoda S, Takano M, Hashida M Hashida Y, Umeyama T, Mihara J, Imahori H, Tsujimoto M, Isoda S, Takano M, Hashida M Hashida Y, Umeyama T, Mihara J, Imahori H, Tsujimoto M, Isoda S, Takano M, Hashida M Development of a novel composite material with carbon nanotubes assisted by self-assembled peptides designed in conjunction with β-sheet formation. Development of a novel composite material with carbon nanotubes assisted by self-assembled peptides designed in conjunction with β-sheet formation. Development of a novel composite material with carbon nanotubes assisted by self-assembled peptides designed in conjunction with β-sheet formation. Journal of pharmaceutical sciences, 101, 3398-3412 Journal of pharmaceutical sciences, 101, 3398-3412 Journal of pharmaceutical sciences, 101, 3398-3412 2012/09 英語 公開
Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Hepatology (Baltimore, Md.), 56, 259-269 Hepatology (Baltimore, Md.), 56, 259-269 Hepatology (Baltimore, Md.), 56, 259-269 2012/07 英語 公開
Miyako E, Deguchi T, Nakajima Y, Yudasaka M, Hagihara Y, Horie M, Shichiri M, Higuchi Y, Yamashita F, Hashida M, Shigeri Y, Yoshida Y, Iijima S Miyako E, Deguchi T, Nakajima Y, Yudasaka M, Hagihara Y, Horie M, Shichiri M, Higuchi Y, Yamashita F, Hashida M, Shigeri Y, Yoshida Y, Iijima S Miyako E, Deguchi T, Nakajima Y, Yudasaka M, Hagihara Y, Horie M, Shichiri M, Higuchi Y, Yamashita F, Hashida M, Shigeri Y, Yoshida Y, Iijima S Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns. Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns. Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns. Proceedings of the National Academy of Sciences of the United States of America, 109, 7523-7528 Proceedings of the National Academy of Sciences of the United States of America, 109, 7523-7528 Proceedings of the National Academy of Sciences of the United States of America, 109, 7523-7528 2012/05 英語 公開
Shimizu K, Kawakami S, Hayashi K, Mori Y, Hashida M, Konishi S Shimizu K, Kawakami S, Hayashi K, Mori Y, Hashida M, Konishi S Shimizu K, Kawakami S, Hayashi K, Mori Y, Hashida M, Konishi S Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice. Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice. Implantable pneumatically actuated microsystem for renal pressure-mediated transfection in mice. Journal of controlled release : official journal of the Controlled Release Society, 159, 85-91 Journal of controlled release : official journal of the Controlled Release Society, 159, 85-91 Journal of controlled release : official journal of the Controlled Release Society, 159, 85-91 2012/04 英語 公開
Zheng Y, Nishikawa M, Ikemura M, Yamashita F, Hashida M Zheng Y, Nishikawa M, Ikemura M, Yamashita F, Hashida M Zheng Y, Nishikawa M, Ikemura M, Yamashita F, Hashida M Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice. Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice. Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice. Journal of pharmaceutical sciences, 101, 552-557 Journal of pharmaceutical sciences, 101, 552-557 Journal of pharmaceutical sciences, 101, 552-557 2012/02 英語 公開
Zhou S, Kawakami S, Higuchi Y, Yamashita F, Hashida M Zhou S, Kawakami S, Higuchi Y, Yamashita F, Hashida M Zhou S, Kawakami S, Higuchi Y, Yamashita F, Hashida M The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice. The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice. The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice. Clinical & experimental metastasis, 29, 63-70 Clinical & experimental metastasis, 29, 63-70 Clinical & experimental metastasis, 29, 63-70 2012/01 英語 公開
Kurosaki T, Higuchi N, Kawakami S, Higuchi Y, Nakamura T, Kitahara T, Hashida M, Sasaki H Kurosaki T, Higuchi N, Kawakami S, Higuchi Y, Nakamura T, Kitahara T, Hashida M, Sasaki H Kurosaki T, Higuchi N, Kawakami S, Higuchi Y, Nakamura T, Kitahara T, Hashida M, Sasaki H Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer. Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer. Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer. Gene, 491, 205-209 Gene, 491, 205-209 Gene, 491, 205-209 2012/01 英語 公開
Saito K, Chang YF, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, Nagai T Saito K, Chang YF, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, Nagai T Saito K, Chang YF, Horikawa K, Hatsugai N, Higuchi Y, Hashida M, Yoshida Y, Matsuda T, Arai Y, Nagai T Luminescent proteins for high-speed single-cell and whole-body imaging. Luminescent proteins for high-speed single-cell and whole-body imaging. Luminescent proteins for high-speed single-cell and whole-body imaging. Nature communications, 3, 1262 Nature communications, 3, 1262 Nature communications, 3, 1262 2012 英語 公開
Shimizu K, Kawakami S, Hayashi K, Kinoshita H, Kuwahara K, Nakao K, Hashida M, Konishi S Shimizu K, Kawakami S, Hayashi K, Kinoshita H, Kuwahara K, Nakao K, Hashida M, Konishi S Shimizu K, Kawakami S, Hayashi K, Kinoshita H, Kuwahara K, Nakao K, Hashida M, Konishi S In vivo site-specific transfection of naked plasmid DNA and siRNAs in mice by using a tissue suction device. In vivo site-specific transfection of naked plasmid DNA and siRNAs in mice by using a tissue suction device. In vivo site-specific transfection of naked plasmid DNA and siRNAs in mice by using a tissue suction device. PloS one, 7, e41319 PloS one, 7, e41319 PloS one, 7, e41319 2012 英語 公開
Umemoto Y, Kawakami S, Otani Y, Higuchi Y, Yamashita F, Hashida M Umemoto Y, Kawakami S, Otani Y, Higuchi Y, Yamashita F, Hashida M Umemoto Y, Kawakami S, Otani Y, Higuchi Y, Yamashita F, Hashida M Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection. Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection. Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection. Biological & pharmaceutical bulletin, 35, 1182-1186 Biological & pharmaceutical bulletin, 35, 1182-1186 Biological & pharmaceutical bulletin, 35, 1182-1186 2012 英語 公開
Tsukamoto M, Okuda T, Okamoto H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Tsukamoto M, Okuda T, Okamoto H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Tsukamoto M, Okuda T, Okamoto H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method. Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method. Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method. Biological & pharmaceutical bulletin, 35, 1178-1181 Biological & pharmaceutical bulletin, 35, 1178-1181 Biological & pharmaceutical bulletin, 35, 1178-1181 2012 英語 公開
Yoshida S, Yamashita F, Itoh T, Hashida M Yoshida S, Yamashita F, Itoh T, Hashida M Yoshida S, Yamashita F, Itoh T, Hashida M Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning. Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning. Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning. Drug metabolism and pharmacokinetics, 27, 506-512 Drug metabolism and pharmacokinetics, 27, 506-512 Drug metabolism and pharmacokinetics, 27, 506-512 2012 英語 公開
Yamashita F, Fujita A, Zhang X, Sasa Y, Mihara K, Hashida M Yamashita F, Fujita A, Zhang X, Sasa Y, Mihara K, Hashida M Yamashita F, Fujita A, Zhang X, Sasa Y, Mihara K, Hashida M Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations. Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations. Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations. Drug metabolism and pharmacokinetics, 27, 280-285 Drug metabolism and pharmacokinetics, 27, 280-285 Drug metabolism and pharmacokinetics, 27, 280-285 2012 英語 公開
Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells. Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells. Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells. Journal of controlled release : official journal of the Controlled Release Society, 156, 195-202 Journal of controlled release : official journal of the Controlled Release Society, 156, 195-202 Journal of controlled release : official journal of the Controlled Release Society, 156, 195-202 2011/12 英語 公開
Un K, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. Journal of controlled release : official journal of the Controlled Release Society, 156, 355-363 Journal of controlled release : official journal of the Controlled Release Society, 156, 355-363 Journal of controlled release : official journal of the Controlled Release Society, 156, 355-363 2011/12 英語 公開
Shimizu K, Higuchi Y, Kozu Y, Hashida M, Konishi S Shimizu K, Higuchi Y, Kozu Y, Hashida M, Konishi S Shimizu K, Higuchi Y, Kozu Y, Hashida M, Konishi S Development of a suction device for stabilizing in vivo real-time imaging of murine tissues. Development of a suction device for stabilizing in vivo real-time imaging of murine tissues. Development of a suction device for stabilizing in vivo real-time imaging of murine tissues. Journal of bioscience and bioengineering, 112, 508-510 Journal of bioscience and bioengineering, 112, 508-510 Journal of bioscience and bioengineering, 112, 508-510 2011/11 英語 公開
Higuchi Y, Wu C, Chang KL, Irie K, Kawakami S, Yamashita F, Hashida M Higuchi Y, Wu C, Chang KL, Irie K, Kawakami S, Yamashita F, Hashida M Higuchi Y, Wu C, Chang KL, Irie K, Kawakami S, Yamashita F, Hashida M Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Biomaterials, 32, 6676-6682 Biomaterials, 32, 6676-6682 Biomaterials, 32, 6676-6682 2011/10 英語 公開
Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. Journal of biotechnology, 154, 205-208 Journal of biotechnology, 154, 205-208 Journal of biotechnology, 154, 205-208 2011/07 英語 公開
Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. Biomaterials, 32, 4659-4669 Biomaterials, 32, 4659-4669 Biomaterials, 32, 4659-4669 2011/07 英語 公開
Wijagkanalan W, Kawakami S, Hashida M Wijagkanalan W, Kawakami S, Hashida M Wijagkanalan W, Kawakami S, Hashida M Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharmaceutical research, 28, 1500-1519 Pharmaceutical research, 28, 1500-1519 Pharmaceutical research, 28, 1500-1519 2011/07 英語 公開
Wijagkanalan W, Kawakami S, Hashida M Wijagkanalan W, Kawakami S, Hashida M Wijagkanalan W, Kawakami S, Hashida M Glycosylated carriers for cell-selective and nuclear delivery of nucleic acids. Glycosylated carriers for cell-selective and nuclear delivery of nucleic acids. Glycosylated carriers for cell-selective and nuclear delivery of nucleic acids. Frontiers in bioscience (Landmark edition), 16, 2970-2987 Frontiers in bioscience (Landmark edition), 16, 2970-2987 Frontiers in bioscience (Landmark edition), 16, 2970-2987 2011/06 英語 公開
Dinh TD, Higuchi Y, Kawakami S, Yamashita F, Hashida M Dinh TD, Higuchi Y, Kawakami S, Yamashita F, Hashida M Dinh TD, Higuchi Y, Kawakami S, Yamashita F, Hashida M Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of pro-inflammatory cytokine production from primary cultured macrophages. Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of pro-inflammatory cytokine production from primary cultured macrophages. Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of pro-inflammatory cytokine production from primary cultured macrophages. Pharmaceutical research, 28, 742-751 Pharmaceutical research, 28, 742-751 Pharmaceutical research, 28, 742-751 2011/04 英語 公開
Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Molecular pharmaceutics, 8, 543-554 Molecular pharmaceutics, 8, 543-554 Molecular pharmaceutics, 8, 543-554 2011/04 英語 公開
Yamashita F, Feng C, Yoshida S, Itoh T, Hashida M Yamashita F, Feng C, Yoshida S, Itoh T, Hashida M Yamashita F, Feng C, Yoshida S, Itoh T, Hashida M Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates. Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates. Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates. Journal of chemical information and modeling, 51, 378-385 Journal of chemical information and modeling, 51, 378-385 Journal of chemical information and modeling, 51, 378-385 2011/02 英語 公開
Wijagkanalan W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Wijagkanalan W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Wijagkanalan W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation. Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation. Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation. Journal of controlled release : official journal of the Controlled Release Society, 149, 42-50 Journal of controlled release : official journal of the Controlled Release Society, 149, 42-50 Journal of controlled release : official journal of the Controlled Release Society, 149, 42-50 2011/01 英語 公開
Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Molecular pharmaceutics, 7, 2069-2076 Molecular pharmaceutics, 7, 2069-2076 Molecular pharmaceutics, 7, 2069-2076 2010/12 英語 公開
Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Biomaterials, 31, 7813-7826 Biomaterials, 31, 7813-7826 Biomaterials, 31, 7813-7826 2010/10 英語 公開
Murakami T, Wijagkanalan W, Hashida M, Tsuchida K Murakami T, Wijagkanalan W, Hashida M, Tsuchida K Murakami T, Wijagkanalan W, Hashida M, Tsuchida K Intracellular drug delivery by genetically engineered high-density lipoprotein nanoparticles. Intracellular drug delivery by genetically engineered high-density lipoprotein nanoparticles. Intracellular drug delivery by genetically engineered high-density lipoprotein nanoparticles. Nanomedicine (London, England), 5, 867-879 Nanomedicine (London, England), 5, 867-879 Nanomedicine (London, England), 5, 867-879 2010/08 英語 公開
Miyano T, Wijagkanalan W, Kawakami S, Yamashita F, Hashida M Miyano T, Wijagkanalan W, Kawakami S, Yamashita F, Hashida M Miyano T, Wijagkanalan W, Kawakami S, Yamashita F, Hashida M Anionic amino acid dendrimer-trastuzumab conjugates for specific internalization in HER2-positive cancer cells. Anionic amino acid dendrimer-trastuzumab conjugates for specific internalization in HER2-positive cancer cells. Anionic amino acid dendrimer-trastuzumab conjugates for specific internalization in HER2-positive cancer cells. Molecular pharmaceutics, 7, 1318-1327 Molecular pharmaceutics, 7, 1318-1327 Molecular pharmaceutics, 7, 1318-1327 2010/08 英語 公開
Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M Hirata K, Maruyama T, Watanabe H, Maeda H, Nakajou K, Iwao Y, Ishima Y, Katsumi H, Hashida M, Otagiri M Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics. Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics. Genetically engineered mannosylated-human serum albumin as a versatile carrier for liver-selective therapeutics. Journal of controlled release : official journal of the Controlled Release Society, 145, 9-16 Journal of controlled release : official journal of the Controlled Release Society, 145, 9-16 Journal of controlled release : official journal of the Controlled Release Society, 145, 9-16 2010/07 英語 公開
Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Bioconjugate chemistry, 21, 1087-1095 Bioconjugate chemistry, 21, 1087-1095 Bioconjugate chemistry, 21, 1087-1095 2010/06 英語 公開
Higuchi Y, Kawakami S, Hashida M Higuchi Y, Kawakami S, Hashida M Higuchi Y, Kawakami S, Hashida M Strategies for in vivo delivery of siRNAs: recent progress. Strategies for in vivo delivery of siRNAs: recent progress. Strategies for in vivo delivery of siRNAs: recent progress. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 24, 195-205 BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 24, 195-205 BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 24, 195-205 2010/06 英語 公開
Murakami T, Tsuchida K, Hashida M, Imahori H Murakami T, Tsuchida K, Hashida M, Imahori H Murakami T, Tsuchida K, Hashida M, Imahori H Size control of lipid-based drug carrier by drug loading. Size control of lipid-based drug carrier by drug loading. Size control of lipid-based drug carrier by drug loading. Molecular bioSystems, 6, 789-791 Molecular bioSystems, 6, 789-791 Molecular bioSystems, 6, 789-791 2010/05 英語 公開
Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M piggyBac transposon-mediated long-term gene expression in mice. piggyBac transposon-mediated long-term gene expression in mice. piggyBac transposon-mediated long-term gene expression in mice. Molecular therapy : the journal of the American Society of Gene Therapy, 18, 707-714 Molecular therapy : the journal of the American Society of Gene Therapy, 18, 707-714 Molecular therapy : the journal of the American Society of Gene Therapy, 18, 707-714 2010/04 英語 公開
Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H Kurosaki T, Kitahara T, Kawakami S, Higuchi Y, Yamaguchi A, Nakagawa H, Kodama Y, Hamamoto T, Hashida M, Sasaki H Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy. Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy. Gamma-polyglutamic acid-coated vectors for effective and safe gene therapy. Journal of controlled release : official journal of the Controlled Release Society, 142, 404-410 Journal of controlled release : official journal of the Controlled Release Society, 142, 404-410 Journal of controlled release : official journal of the Controlled Release Society, 142, 404-410 2010/03 英語 公開
Mizuno Y, Naoi T, Nishikawa M, Rattanakiat S, Hamaguchi N, Hashida M, Takakura Y Mizuno Y, Naoi T, Nishikawa M, Rattanakiat S, Hamaguchi N, Hashida M, Takakura Y Mizuno Y, Naoi T, Nishikawa M, Rattanakiat S, Hamaguchi N, Hashida M, Takakura Y Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice. Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice. Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice. Journal of controlled release : official journal of the Controlled Release Society, 141, 252-259 Journal of controlled release : official journal of the Controlled Release Society, 141, 252-259 Journal of controlled release : official journal of the Controlled Release Society, 141, 252-259 2010/01 英語 公開
Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Human gene therapy, 21, 65-74 Human gene therapy, 21, 65-74 Human gene therapy, 21, 65-74 2010/01 英語 公開
Zhou S, Kawakami S, Yamashita F, Hashida M Zhou S, Kawakami S, Yamashita F, Hashida M Zhou S, Kawakami S, Yamashita F, Hashida M Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Cancer letters, 287, 75-81 Cancer letters, 287, 75-81 Cancer letters, 287, 75-81 2010/01 英語 公開
Mukai H, Kawakami S, Takahashi H, Satake K, Yamashita F, Hashida M Mukai H, Kawakami S, Takahashi H, Satake K, Yamashita F, Hashida M Mukai H, Kawakami S, Takahashi H, Satake K, Yamashita F, Hashida M Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Biological & pharmaceutical bulletin, 33, 1627-1632 Biological & pharmaceutical bulletin, 33, 1627-1632 Biological & pharmaceutical bulletin, 33, 1627-1632 2010 英語 公開
Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M [Development and therapeutic application of transposon-based vectors]. [Development and therapeutic application of transposon-based vectors]. [Development and therapeutic application of transposon-based vectors]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129, 1433-1443 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129, 1433-1443 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129, 1433-1443 2009/12 日本語 公開
Katsumi H, Nishikawa M, Yasui H, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yasui H, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yasui H, Yamashita F, Hashida M Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice. Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice. Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice. Journal of controlled release : official journal of the Controlled Release Society, 140, 12-17 Journal of controlled release : official journal of the Controlled Release Society, 140, 12-17 Journal of controlled release : official journal of the Controlled Release Society, 140, 12-17 2009/11 英語 公開
Mukai H, Kawakami S, Kamiya Y, Ma F, Takahashi H, Satake K, Terao K, Kotera H, Yamashita F, Hashida M Mukai H, Kawakami S, Kamiya Y, Ma F, Takahashi H, Satake K, Terao K, Kotera H, Yamashita F, Hashida M Mukai H, Kawakami S, Kamiya Y, Ma F, Takahashi H, Satake K, Terao K, Kotera H, Yamashita F, Hashida M Pressure-mediated transfection of murine spleen and liver. Pressure-mediated transfection of murine spleen and liver. Pressure-mediated transfection of murine spleen and liver. Human gene therapy, 20, 1157-1167 Human gene therapy, 20, 1157-1167 Human gene therapy, 20, 1157-1167 2009/10 英語 公開
Nakamura K, Kuramoto Y, Mukai H, Kawakami S, Higuchi Y, Hashida M Nakamura K, Kuramoto Y, Mukai H, Kawakami S, Higuchi Y, Hashida M Nakamura K, Kuramoto Y, Mukai H, Kawakami S, Higuchi Y, Hashida M Enhanced gene transfection in macrophages by histidine-conjugated mannosylated cationic liposomes. Enhanced gene transfection in macrophages by histidine-conjugated mannosylated cationic liposomes. Enhanced gene transfection in macrophages by histidine-conjugated mannosylated cationic liposomes. Biological & pharmaceutical bulletin, 32, 1628-1631 Biological & pharmaceutical bulletin, 32, 1628-1631 Biological & pharmaceutical bulletin, 32, 1628-1631 2009/09 英語 公開
Sugao Y, Watanabe K, Higuchi Y, Kurihara R, Kawakami S, Hashida M, Katayama Y, Niidome T Sugao Y, Watanabe K, Higuchi Y, Kurihara R, Kawakami S, Hashida M, Katayama Y, Niidome T Sugao Y, Watanabe K, Higuchi Y, Kurihara R, Kawakami S, Hashida M, Katayama Y, Niidome T NFkappaB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice. NFkappaB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice. NFkappaB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice. Bioorganic & medicinal chemistry, 17, 4990-4995 Bioorganic & medicinal chemistry, 17, 4990-4995 Bioorganic & medicinal chemistry, 17, 4990-4995 2009/07 英語 公開
Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase. Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase. Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase. Journal of controlled release : official journal of the Controlled Release Society, 137, 110-115 Journal of controlled release : official journal of the Controlled Release Society, 137, 110-115 Journal of controlled release : official journal of the Controlled Release Society, 137, 110-115 2009/07 英語 公開
Satoh T, Higuchi Y, Kawakami S, Hashida M, Kagechika H, Shudo K, Yokoyama M Satoh T, Higuchi Y, Kawakami S, Hashida M, Kagechika H, Shudo K, Yokoyama M Satoh T, Higuchi Y, Kawakami S, Hashida M, Kagechika H, Shudo K, Yokoyama M Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control. Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control. Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control. Journal of controlled release : official journal of the Controlled Release Society, 136, 187-195 Journal of controlled release : official journal of the Controlled Release Society, 136, 187-195 Journal of controlled release : official journal of the Controlled Release Society, 136, 187-195 2009/06 英語 公開
Okuda T, Kawakami S, Higuchi Y, Satoh T, Oka Y, Yokoyama M, Yamashita F, Hashida M Okuda T, Kawakami S, Higuchi Y, Satoh T, Oka Y, Yokoyama M, Yamashita F, Hashida M Okuda T, Kawakami S, Higuchi Y, Satoh T, Oka Y, Yokoyama M, Yamashita F, Hashida M Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles. Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles. Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles. International journal of pharmaceutics, 373, 100-106 International journal of pharmaceutics, 373, 100-106 International journal of pharmaceutics, 373, 100-106 2009/05 英語 公開
Nishikawa M, Hashida M, Takakura Y Nishikawa M, Hashida M, Takakura Y Nishikawa M, Hashida M, Takakura Y Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis. Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis. Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis. Advanced drug delivery reviews, 61, 319-326 Advanced drug delivery reviews, 61, 319-326 Advanced drug delivery reviews, 61, 319-326 2009/04 英語 公開
Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice. Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice. Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice. Journal of pharmaceutical sciences, 98, 1193-1197 Journal of pharmaceutical sciences, 98, 1193-1197 Journal of pharmaceutical sciences, 98, 1193-1197 2009/03 英語 公開
Saito Y, Higuchi Y, Kawakami S, Yamashita F, Hashida M Saito Y, Higuchi Y, Kawakami S, Yamashita F, Hashida M Saito Y, Higuchi Y, Kawakami S, Yamashita F, Hashida M Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Human gene therapy, 20, 137-145 Human gene therapy, 20, 137-145 Human gene therapy, 20, 137-145 2009/02 英語 公開
Ito Y, Kawakami S, Charoensit P, Higuchi Y, Hashida M Ito Y, Kawakami S, Charoensit P, Higuchi Y, Hashida M Ito Y, Kawakami S, Charoensit P, Higuchi Y, Hashida M Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice. Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice. Evaluation of proinflammatory cytokine production and liver injury induced by plasmid DNA/cationic liposome complexes with various mixing ratios in mice. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71, 303-309 European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71, 303-309 European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 71, 303-309 2009/02 英語 公開
Shiose Y, Kuga H, Ohki H, Ikeda M, Yamashita F, Hashida M Shiose Y, Kuga H, Ohki H, Ikeda M, Yamashita F, Hashida M Shiose Y, Kuga H, Ohki H, Ikeda M, Yamashita F, Hashida M Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates. Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates. Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates. Bioconjugate chemistry, 20, 60-70 Bioconjugate chemistry, 20, 60-70 Bioconjugate chemistry, 20, 60-70 2009/01 英語 公開
Huang H, Sakurai F, Higuchi Y, Kawakami S, Hashida M, Kawabata K, Mizuguchi H Huang H, Sakurai F, Higuchi Y, Kawakami S, Hashida M, Kawabata K, Mizuguchi H Huang H, Sakurai F, Higuchi Y, Kawakami S, Hashida M, Kawabata K, Mizuguchi H Suppressive effects of sugar-modified cationic liposome/NF-kappaB decoy complexes on adenovirus vector-induced innate immune responses. Suppressive effects of sugar-modified cationic liposome/NF-kappaB decoy complexes on adenovirus vector-induced innate immune responses. Suppressive effects of sugar-modified cationic liposome/NF-kappaB decoy complexes on adenovirus vector-induced innate immune responses. Journal of controlled release : official journal of the Controlled Release Society, 133, 139-145 Journal of controlled release : official journal of the Controlled Release Society, 133, 139-145 Journal of controlled release : official journal of the Controlled Release Society, 133, 139-145 2009/01 英語 公開
Mukai H, Kawakami S, Hashida M Mukai H, Kawakami S, Hashida M Mukai H, Kawakami S, Hashida M [Development of nucleic acid transfection technology to the kidney]. [Development of nucleic acid transfection technology to the kidney]. [Development of nucleic acid transfection technology to the kidney]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 1577-1586 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 1577-1586 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 1577-1586 2008/11 日本語 公開
Wijagkanalan W, Higuchi Y, Kawakami S, Teshima M, Sasaki H, Hashida M Wijagkanalan W, Higuchi Y, Kawakami S, Teshima M, Sasaki H, Hashida M Wijagkanalan W, Higuchi Y, Kawakami S, Teshima M, Sasaki H, Hashida M Enhanced anti-inflammation of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin-induced lung inflammation model. Enhanced anti-inflammation of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin-induced lung inflammation model. Enhanced anti-inflammation of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin-induced lung inflammation model. Molecular pharmacology, 74, 1183-1192 Molecular pharmacology, 74, 1183-1192 Molecular pharmacology, 74, 1183-1192 2008/11 英語 公開
Kobayashi Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Kobayashi Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Kobayashi Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis. Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis. Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis. Cancer science, 99, 1546-1552 Cancer science, 99, 1546-1552 Cancer science, 99, 1546-1552 2008/08 英語 公開
Mukai H, Kawakami S, Hashida M Mukai H, Kawakami S, Hashida M Mukai H, Kawakami S, Hashida M Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney. Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney. Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney. Biochemical and biophysical research communications, 372, 383-387 Biochemical and biophysical research communications, 372, 383-387 Biochemical and biophysical research communications, 372, 383-387 2008/08 英語 公開
Okuda T, Kawakami S, Yokoyama M, Yamamoto T, Yamashita F, Hashida M Okuda T, Kawakami S, Yokoyama M, Yamamoto T, Yamashita F, Hashida M Okuda T, Kawakami S, Yokoyama M, Yamamoto T, Yamashita F, Hashida M Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. International journal of pharmaceutics, 357, 318-322 International journal of pharmaceutics, 357, 318-322 International journal of pharmaceutics, 357, 318-322 2008/06 英語 公開
Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Pharmacokinetic considerations regarding non-viral cancer gene therapy. Pharmacokinetic considerations regarding non-viral cancer gene therapy. Pharmacokinetic considerations regarding non-viral cancer gene therapy. Cancer science, 99, 856-862 Cancer science, 99, 856-862 Cancer science, 99, 856-862 2008/05 英語 公開
Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice. Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice. Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice. The journal of gene medicine, 10, 392-399 The journal of gene medicine, 10, 392-399 The journal of gene medicine, 10, 392-399 2008/04 英語 公開
Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. Journal of controlled release : official journal of the Controlled Release Society, 126, 274-280 Journal of controlled release : official journal of the Controlled Release Society, 126, 274-280 Journal of controlled release : official journal of the Controlled Release Society, 126, 274-280 2008/03 英語 公開
Higuchi Y, Kawakami S, Hashida M Higuchi Y, Kawakami S, Hashida M Higuchi Y, Kawakami S, Hashida M [Development of cell-selective targeting systems of NFkappaB decoy for inflammation therapy]. [Development of cell-selective targeting systems of NFkappaB decoy for inflammation therapy]. [Development of cell-selective targeting systems of NFkappaB decoy for inflammation therapy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 209-218 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 209-218 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 128, 209-218 2008/02 日本語 公開
Yamashita F, Hara H, Ito T, Hashida M Yamashita F, Hara H, Ito T, Hashida M Yamashita F, Hara H, Ito T, Hashida M Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism. Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism. Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism. Journal of chemical information and modeling, 48, 364-369 Journal of chemical information and modeling, 48, 364-369 Journal of chemical information and modeling, 48, 364-369 2008/02 英語 公開
Kawakami S, Higuchi Y, Hashida M Kawakami S, Higuchi Y, Hashida M Kawakami S, Higuchi Y, Hashida M Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide. Journal of pharmaceutical sciences, 97, 726-745 Journal of pharmaceutical sciences, 97, 726-745 Journal of pharmaceutical sciences, 97, 726-745 2008/02 英語 公開
Chansri N, Kawakami S, Yokoyama M, Yamamoto T, Charoensit P, Hashida M Chansri N, Kawakami S, Yokoyama M, Yamamoto T, Charoensit P, Hashida M Chansri N, Kawakami S, Yokoyama M, Yamamoto T, Charoensit P, Hashida M Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice. Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice. Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice. Pharmaceutical research, 25, 428-434 Pharmaceutical research, 25, 428-434 Pharmaceutical research, 25, 428-434 2008/02 英語 公開
Katsumi H, Nishikawa M, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yamashita F, Hashida M Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice. Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice. Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice. Transplantation, 85, 264-269 Transplantation, 85, 264-269 Transplantation, 85, 264-269 2008/01 英語 公開
Higuchi Y, Oka M, Kawakami S, Hashida M Higuchi Y, Oka M, Kawakami S, Hashida M Higuchi Y, Oka M, Kawakami S, Hashida M Mannosylated semiconductor quantum dots for the labeling of macrophages. Mannosylated semiconductor quantum dots for the labeling of macrophages. Mannosylated semiconductor quantum dots for the labeling of macrophages. Journal of controlled release : official journal of the Controlled Release Society, 125, 131-136 Journal of controlled release : official journal of the Controlled Release Society, 125, 131-136 Journal of controlled release : official journal of the Controlled Release Society, 125, 131-136 2008/01 英語 公開
Wijagkanalan W, Kawakami S, Takenaga M, Igarashi R, Yamashita F, Hashida M Wijagkanalan W, Kawakami S, Takenaga M, Igarashi R, Yamashita F, Hashida M Wijagkanalan W, Kawakami S, Takenaga M, Igarashi R, Yamashita F, Hashida M Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. Journal of controlled release : official journal of the Controlled Release Society, 125, 121-130 Journal of controlled release : official journal of the Controlled Release Society, 125, 121-130 Journal of controlled release : official journal of the Controlled Release Society, 125, 121-130 2008/01 英語 公開
Charoensit P, Kawakami S, Higuchi Y, Hashida M Charoensit P, Kawakami S, Higuchi Y, Hashida M Charoensit P, Kawakami S, Higuchi Y, Hashida M Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice. Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice. Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice. The journal of gene medicine, 10, 61-69 The journal of gene medicine, 10, 61-69 The journal of gene medicine, 10, 61-69 2008/01 英語 公開
Thanaketpaisarn O, Nishikawa M, Okabe T, Yamashita F, Hashida M Thanaketpaisarn O, Nishikawa M, Okabe T, Yamashita F, Hashida M Thanaketpaisarn O, Nishikawa M, Okabe T, Yamashita F, Hashida M Insertion of nuclear factor-kappaB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells. Insertion of nuclear factor-kappaB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells. Insertion of nuclear factor-kappaB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells. Journal of biotechnology, 133, 36-41 Journal of biotechnology, 133, 36-41 Journal of biotechnology, 133, 36-41 2008/01 英語 公開
Hyoudou K, Nishikawa M, Kobayashi Y, Ikemura M, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Ikemura M, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Ikemura M, Yamashita F, Hashida M SOD derivatives prevent metastatic tumor growth aggravated by tumor removal. SOD derivatives prevent metastatic tumor growth aggravated by tumor removal. SOD derivatives prevent metastatic tumor growth aggravated by tumor removal. Clinical & experimental metastasis, 25, 531-536 Clinical & experimental metastasis, 25, 531-536 Clinical & experimental metastasis, 25, 531-536 2008 英語 公開
Shiose Y, Ochi Y, Kuga H, Yamashita F, Hashida M Shiose Y, Ochi Y, Kuga H, Yamashita F, Hashida M Shiose Y, Ochi Y, Kuga H, Yamashita F, Hashida M Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors. Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors. Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors. Biological & pharmaceutical bulletin, 30, 2365-2370 Biological & pharmaceutical bulletin, 30, 2365-2370 Biological & pharmaceutical bulletin, 30, 2365-2370 2007/12 英語 公開
Feng C, Yamashita F, Hashida M Feng C, Yamashita F, Hashida M Feng C, Yamashita F, Hashida M Automated extraction of information from the literature on chemical-CYP3A4 interactions. Automated extraction of information from the literature on chemical-CYP3A4 interactions. Automated extraction of information from the literature on chemical-CYP3A4 interactions. Journal of chemical information and modeling, 47, 2449-2455 Journal of chemical information and modeling, 47, 2449-2455 Journal of chemical information and modeling, 47, 2449-2455 2007/11 英語 公開
Kuramoto Y, Hashida M Kuramoto Y, Hashida M Kuramoto Y, Hashida M [Immunotherapy against peritoneal dissemination by immunostimulatory CpG DNA]. [Immunotherapy against peritoneal dissemination by immunostimulatory CpG DNA]. [Immunotherapy against peritoneal dissemination by immunostimulatory CpG DNA]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 127, 1533-1540 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 127, 1533-1540 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 127, 1533-1540 2007/10 日本語 公開
Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells. Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells. Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells. Journal of controlled release : official journal of the Controlled Release Society, 122, 151-158 Journal of controlled release : official journal of the Controlled Release Society, 122, 151-158 Journal of controlled release : official journal of the Controlled Release Society, 122, 151-158 2007/09 英語 公開
Nemoto T, Kawakami S, Yamashita F, Hashida M Nemoto T, Kawakami S, Yamashita F, Hashida M Nemoto T, Kawakami S, Yamashita F, Hashida M Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. Journal of controlled release : official journal of the Controlled Release Society, 121, 74-80 Journal of controlled release : official journal of the Controlled Release Society, 121, 74-80 Journal of controlled release : official journal of the Controlled Release Society, 121, 74-80 2007/08 英語 公開
Lu Y, Kawakami S, Yamashita F, Hashida M Lu Y, Kawakami S, Yamashita F, Hashida M Lu Y, Kawakami S, Yamashita F, Hashida M Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Biomaterials, 28, 3255-3262 Biomaterials, 28, 3255-3262 Biomaterials, 28, 3255-3262 2007/07 英語 公開
Katsumi H, Nishikawa M, Hashida M Katsumi H, Nishikawa M, Hashida M Katsumi H, Nishikawa M, Hashida M Development of nitric oxide donors for the treatment of cardiovascular diseases. Development of nitric oxide donors for the treatment of cardiovascular diseases. Development of nitric oxide donors for the treatment of cardiovascular diseases. Cardiovascular & hematological agents in medicinal chemistry, 5, 204-208 Cardiovascular & hematological agents in medicinal chemistry, 5, 204-208 Cardiovascular & hematological agents in medicinal chemistry, 5, 204-208 2007/07 英語 公開
Kawakami S, Hashida M Kawakami S, Hashida M Kawakami S, Hashida M Targeted delivery systems of small interfering RNA by systemic administration. Targeted delivery systems of small interfering RNA by systemic administration. Targeted delivery systems of small interfering RNA by systemic administration. Drug metabolism and pharmacokinetics, 22, 142-151 Drug metabolism and pharmacokinetics, 22, 142-151 Drug metabolism and pharmacokinetics, 22, 142-151 2007/06 英語 公開
Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Sano K, Yamaguchi H, Maeda A, Saito K, Takakura Y, Hashida M Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Sano K, Yamaguchi H, Maeda A, Saito K, Takakura Y, Hashida M Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Sano K, Yamaguchi H, Maeda A, Saito K, Takakura Y, Hashida M Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL11) by chemical modification with polyethylene glycol. Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL11) by chemical modification with polyethylene glycol. Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL11) by chemical modification with polyethylene glycol. Journal of controlled release : official journal of the Controlled Release Society, 119, 271-278 Journal of controlled release : official journal of the Controlled Release Society, 119, 271-278 Journal of controlled release : official journal of the Controlled Release Society, 119, 271-278 2007/06 英語 公開
Terada T, Mizobata M, Kawakami S, Yamashita F, Hashida M Terada T, Mizobata M, Kawakami S, Yamashita F, Hashida M Terada T, Mizobata M, Kawakami S, Yamashita F, Hashida M Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes. Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes. Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes. Journal of controlled release : official journal of the Controlled Release Society, 119, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 119, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 119, 262-270 2007/06 英語 公開
Hyoudou K, Nishikawa M, Kobayashi Y, Mukai S, Ikemura M, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Mukai S, Ikemura M, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Mukai S, Ikemura M, Kuramoto Y, Yamashita F, Hashida M Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice. Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice. Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice. Journal of controlled release : official journal of the Controlled Release Society, 119, 121-127 Journal of controlled release : official journal of the Controlled Release Society, 119, 121-127 Journal of controlled release : official journal of the Controlled Release Society, 119, 121-127 2007/05 英語 公開
Shigeta K, Kawakami S, Higuchi Y, Okuda T, Yagi H, Yamashita F, Hashida M Shigeta K, Kawakami S, Higuchi Y, Okuda T, Yagi H, Yamashita F, Hashida M Shigeta K, Kawakami S, Higuchi Y, Okuda T, Yagi H, Yamashita F, Hashida M Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. Journal of controlled release : official journal of the Controlled Release Society, 118, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 118, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 118, 262-270 2007/04 英語 公開
Sato A, Takagi M, Shimamoto A, Kawakami S, Hashida M Sato A, Takagi M, Shimamoto A, Kawakami S, Hashida M Sato A, Takagi M, Shimamoto A, Kawakami S, Hashida M Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice. Biomaterials, 28, 1434-1442 Biomaterials, 28, 1434-1442 Biomaterials, 28, 1434-1442 2007/03 英語 公開
Shiose Y, Kuga H, Yamashita F, Hashida M Shiose Y, Kuga H, Yamashita F, Hashida M Shiose Y, Kuga H, Yamashita F, Hashida M Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f. Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f. Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f. Journal of pharmaceutical and biomedical analysis, 43, 1290-1296 Journal of pharmaceutical and biomedical analysis, 43, 1290-1296 Journal of pharmaceutical and biomedical analysis, 43, 1290-1296 2007/03 英語 公開
Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Analysis of in vivo nuclear factor-kappaB activation during liver inflammation in mice: prevention by catalase delivery. Analysis of in vivo nuclear factor-kappaB activation during liver inflammation in mice: prevention by catalase delivery. Analysis of in vivo nuclear factor-kappaB activation during liver inflammation in mice: prevention by catalase delivery. Molecular pharmacology, 71, 446-453 Molecular pharmacology, 71, 446-453 Molecular pharmacology, 71, 446-453 2007/02 英語 公開
Nagayama S, Ogawara K, Minato K, Fukuoka Y, Takakura Y, Hashida M, Higaki K, Kimura T Nagayama S, Ogawara K, Minato K, Fukuoka Y, Takakura Y, Hashida M, Higaki K, Kimura T Nagayama S, Ogawara K, Minato K, Fukuoka Y, Takakura Y, Hashida M, Higaki K, Kimura T Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor. Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor. Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor. International journal of pharmaceutics, 329, 192-198 International journal of pharmaceutics, 329, 192-198 International journal of pharmaceutics, 329, 192-198 2007/02 英語 公開
Higuchi Y, Kawakami S, Yamashita F, Hashida M Higuchi Y, Kawakami S, Yamashita F, Hashida M Higuchi Y, Kawakami S, Yamashita F, Hashida M The potential role of fucosylated cationic liposome/NFkappaB decoy complexes in the treatment of cytokine-related liver disease. The potential role of fucosylated cationic liposome/NFkappaB decoy complexes in the treatment of cytokine-related liver disease. The potential role of fucosylated cationic liposome/NFkappaB decoy complexes in the treatment of cytokine-related liver disease. Biomaterials, 28, 532-539 Biomaterials, 28, 532-539 Biomaterials, 28, 532-539 2007/01 英語 公開
Okuda T, Kawakami S, Akimoto N, Niidome T, Yamashita F, Hashida M Okuda T, Kawakami S, Akimoto N, Niidome T, Yamashita F, Hashida M Okuda T, Kawakami S, Akimoto N, Niidome T, Yamashita F, Hashida M PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. Journal of controlled release : official journal of the Controlled Release Society, 116, 330-336 Journal of controlled release : official journal of the Controlled Release Society, 116, 330-336 Journal of controlled release : official journal of the Controlled Release Society, 116, 330-336 2006/12 英語 公開
Suzuki S, Kawakami S, Chansri N, Yamashita F, Hashida M Suzuki S, Kawakami S, Chansri N, Yamashita F, Hashida M Suzuki S, Kawakami S, Chansri N, Yamashita F, Hashida M Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes. Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes. Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes. Journal of controlled release : official journal of the Controlled Release Society, 116, 58-63 Journal of controlled release : official journal of the Controlled Release Society, 116, 58-63 Journal of controlled release : official journal of the Controlled Release Society, 116, 58-63 2006/11 英語 公開
Hyoudou K, Nishikawa M, Kobayashi Y, Umeyama Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Umeyama Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Umeyama Y, Yamashita F, Hashida M PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal. PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal. PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal. Free radical biology & medicine, 41, 1449-1458 Free radical biology & medicine, 41, 1449-1458 Free radical biology & medicine, 41, 1449-1458 2006/11 英語 公開
Kuramoto Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Kuramoto Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Kuramoto Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex. Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex. Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex. Journal of controlled release : official journal of the Controlled Release Society, 115, 226-233 Journal of controlled release : official journal of the Controlled Release Society, 115, 226-233 Journal of controlled release : official journal of the Controlled Release Society, 115, 226-233 2006/10 英語 公開
Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Nakanishi K, Takemura S, Maeda A, Saito K, Takakura Y, Hashida M Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Nakanishi K, Takemura S, Maeda A, Saito K, Takakura Y, Hashida M Takagi A, Yamashita N, Yoshioka T, Takaishi Y, Nakanishi K, Takemura S, Maeda A, Saito K, Takakura Y, Hashida M Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL11). Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL11). Incorporation into a biodegradable hyaluronic acid matrix enhances in vivo efficacy of recombinant human interleukin 11 (rhIL11). Journal of controlled release : official journal of the Controlled Release Society, 115, 134-139 Journal of controlled release : official journal of the Controlled Release Society, 115, 134-139 Journal of controlled release : official journal of the Controlled Release Society, 115, 134-139 2006/10 英語 公開
Terada T, Mizobata M, Kawakami S, Yabe Y, Yamashita F, Hashida M Terada T, Mizobata M, Kawakami S, Yabe Y, Yamashita F, Hashida M Terada T, Mizobata M, Kawakami S, Yabe Y, Yamashita F, Hashida M Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. Journal of drug targeting, 14, 536-545 Journal of drug targeting, 14, 536-545 Journal of drug targeting, 14, 536-545 2006/09 英語 公開
Saito Y, Kawakami S, Yabe Y, Yamashita F, Hashida M Saito Y, Kawakami S, Yabe Y, Yamashita F, Hashida M Saito Y, Kawakami S, Yabe Y, Yamashita F, Hashida M Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HEPG2 cells. Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HEPG2 cells. Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HEPG2 cells. Biological & pharmaceutical bulletin, 29, 1986-1990 Biological & pharmaceutical bulletin, 29, 1986-1990 Biological & pharmaceutical bulletin, 29, 1986-1990 2006/09 英語 公開
Ma SF, Nishikawa M, Yabe Y, Yamashita F, Hashida M Ma SF, Nishikawa M, Yabe Y, Yamashita F, Hashida M Ma SF, Nishikawa M, Yabe Y, Yamashita F, Hashida M Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution. Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution. Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution. Biological & pharmaceutical bulletin, 29, 1926-1930 Biological & pharmaceutical bulletin, 29, 1926-1930 Biological & pharmaceutical bulletin, 29, 1926-1930 2006/09 英語 公開
Chansri N, Kawakami S, Yamashita F, Hashida M Chansri N, Kawakami S, Yamashita F, Hashida M Chansri N, Kawakami S, Yamashita F, Hashida M Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice. Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice. Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice. International journal of pharmaceutics, 321, 42-49 International journal of pharmaceutics, 321, 42-49 International journal of pharmaceutics, 321, 42-49 2006/09 英語 公開
Yeeprae W, Kawakami S, Yamashita F, Hashida M Yeeprae W, Kawakami S, Yamashita F, Hashida M Yeeprae W, Kawakami S, Yamashita F, Hashida M Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages. Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages. Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages. Journal of controlled release : official journal of the Controlled Release Society, 114, 193-201 Journal of controlled release : official journal of the Controlled Release Society, 114, 193-201 Journal of controlled release : official journal of the Controlled Release Society, 114, 193-201 2006/08 英語 公開
Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. Journal of controlled release : official journal of the Controlled Release Society, 114, 69-77 Journal of controlled release : official journal of the Controlled Release Society, 114, 69-77 Journal of controlled release : official journal of the Controlled Release Society, 114, 69-77 2006/08 英語 公開
Hattori Y, Kawakami S, Nakamura K, Yamashita F, Hashida M Hattori Y, Kawakami S, Nakamura K, Yamashita F, Hashida M Hattori Y, Kawakami S, Nakamura K, Yamashita F, Hashida M Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route. Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route. Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route. The Journal of pharmacology and experimental therapeutics, 318, 828-834 The Journal of pharmacology and experimental therapeutics, 318, 828-834 The Journal of pharmacology and experimental therapeutics, 318, 828-834 2006/08 英語 公開
Higuchi Y, Hashida M Higuchi Y, Hashida M Higuchi Y, Hashida M [Pharmaceutical device of IFN]. [Pharmaceutical device of IFN]. [Pharmaceutical device of IFN]. Nihon rinsho. Japanese journal of clinical medicine, 64, 1374-1379 Nihon rinsho. Japanese journal of clinical medicine, 64, 1374-1379 Nihon rinsho. Japanese journal of clinical medicine, 64, 1374-1379 2006/07 日本語 公開
Higuchi Y, Kawakami S, Fumoto S, Yamashita F, Hashida M Higuchi Y, Kawakami S, Fumoto S, Yamashita F, Hashida M Higuchi Y, Kawakami S, Fumoto S, Yamashita F, Hashida M Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration. Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration. Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration. Biological & pharmaceutical bulletin, 29, 1521-1523 Biological & pharmaceutical bulletin, 29, 1521-1523 Biological & pharmaceutical bulletin, 29, 1521-1523 2006/07 英語 公開
Hattori Y, Kawakami S, Lu Y, Nakamura K, Yamashita F, Hashida M Hattori Y, Kawakami S, Lu Y, Nakamura K, Yamashita F, Hashida M Hattori Y, Kawakami S, Lu Y, Nakamura K, Yamashita F, Hashida M Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration. Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration. Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration. The journal of gene medicine, 8, 824-834 The journal of gene medicine, 8, 824-834 The journal of gene medicine, 8, 824-834 2006/07 英語 公開
Higuchi Y, Kawakami S, Oka M, Yabe Y, Yamashita F, Hashida M Higuchi Y, Kawakami S, Oka M, Yabe Y, Yamashita F, Hashida M Higuchi Y, Kawakami S, Oka M, Yabe Y, Yamashita F, Hashida M Intravenous administration of mannosylated cationic liposome/NFkappaB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. Intravenous administration of mannosylated cationic liposome/NFkappaB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. Intravenous administration of mannosylated cationic liposome/NFkappaB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. FEBS letters, 580, 3706-3714 FEBS letters, 580, 3706-3714 FEBS letters, 580, 3706-3714 2006/06 英語 公開
Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins. Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins. Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins. International journal of pharmaceutics, 316, 117-123 International journal of pharmaceutics, 316, 117-123 International journal of pharmaceutics, 316, 117-123 2006/06 英語 公開
Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy. Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy. Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy. Journal of pharmaceutical and biomedical analysis, 41, 966-972 Journal of pharmaceutical and biomedical analysis, 41, 966-972 Journal of pharmaceutical and biomedical analysis, 41, 966-972 2006/06 英語 公開
Kawakami S, Ito Y, Charoensit P, Yamashita F, Hashida M Kawakami S, Ito Y, Charoensit P, Yamashita F, Hashida M Kawakami S, Ito Y, Charoensit P, Yamashita F, Hashida M Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. The Journal of pharmacology and experimental therapeutics, 317, 1382-1390 The Journal of pharmacology and experimental therapeutics, 317, 1382-1390 The Journal of pharmacology and experimental therapeutics, 317, 1382-1390 2006/06 英語 公開
Yamashita F, Itoh T, Hara H, Hashida M Yamashita F, Itoh T, Hara H, Hashida M Yamashita F, Itoh T, Hara H, Hashida M Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique. Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique. Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique. Journal of chemical information and modeling, 46, 1054-1059 Journal of chemical information and modeling, 46, 1054-1059 Journal of chemical information and modeling, 46, 1054-1059 2006/05 英語 公開
Nishikawa M, Hashida M Nishikawa M, Hashida M Nishikawa M, Hashida M Inhibition of tumour metastasis by targeted delivery of antioxidant enzymes. Inhibition of tumour metastasis by targeted delivery of antioxidant enzymes. Inhibition of tumour metastasis by targeted delivery of antioxidant enzymes. Expert opinion on drug delivery, 3, 355-369 Expert opinion on drug delivery, 3, 355-369 Expert opinion on drug delivery, 3, 355-369 2006/05 英語 公開
Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Terada T, Nishikawa M, Yamashita F, Hashida M Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes. Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes. Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes. Biological & pharmaceutical bulletin, 29, 613-618 Biological & pharmaceutical bulletin, 29, 613-618 Biological & pharmaceutical bulletin, 29, 613-618 2006/04 英語 公開
Terada T, Iwai M, Kawakami S, Yamashita F, Hashida M Terada T, Iwai M, Kawakami S, Yamashita F, Hashida M Terada T, Iwai M, Kawakami S, Yamashita F, Hashida M Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. Journal of controlled release : official journal of the Controlled Release Society, 111, 333-342 Journal of controlled release : official journal of the Controlled Release Society, 111, 333-342 Journal of controlled release : official journal of the Controlled Release Society, 111, 333-342 2006/04 英語 公開
Ishimoto N, Nemoto T, Nagayoshi K, Yamashita F, Hashida M Ishimoto N, Nemoto T, Nagayoshi K, Yamashita F, Hashida M Ishimoto N, Nemoto T, Nagayoshi K, Yamashita F, Hashida M Improved anti-oxidant activity of superoxide dismutase by direct chemical modification. Improved anti-oxidant activity of superoxide dismutase by direct chemical modification. Improved anti-oxidant activity of superoxide dismutase by direct chemical modification. Journal of controlled release : official journal of the Controlled Release Society, 111, 204-211 Journal of controlled release : official journal of the Controlled Release Society, 111, 204-211 Journal of controlled release : official journal of the Controlled Release Society, 111, 204-211 2006/03 英語 公開
Kawakami S, Suzuki S, Yamashita F, Hashida M Kawakami S, Suzuki S, Yamashita F, Hashida M Kawakami S, Suzuki S, Yamashita F, Hashida M Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes. Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes. Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes. Journal of controlled release : official journal of the Controlled Release Society, 110, 514-521 Journal of controlled release : official journal of the Controlled Release Society, 110, 514-521 Journal of controlled release : official journal of the Controlled Release Society, 110, 514-521 2006/02 英語 公開
Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Liver targeting of catalase by cationization for prevention of acute liver failure in mice. Liver targeting of catalase by cationization for prevention of acute liver failure in mice. Liver targeting of catalase by cationization for prevention of acute liver failure in mice. Journal of controlled release : official journal of the Controlled Release Society, 110, 273-282 Journal of controlled release : official journal of the Controlled Release Society, 110, 273-282 Journal of controlled release : official journal of the Controlled Release Society, 110, 273-282 2006/01 英語 公開
Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F, Hashida M Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F, Hashida M Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F, Hashida M Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung. Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung. Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung. The journal of gene medicine, 8, 1, 53-62 The journal of gene medicine, 8, 1, 53-62 The journal of gene medicine, 8, 1, 53-62 2006/01 英語 公開
Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase. Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase. Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase. Clinical & experimental metastasis, 23, 269-278 Clinical & experimental metastasis, 23, 269-278 Clinical & experimental metastasis, 23, 269-278 2006 英語 公開
Yamashita F, Fujiwara S, Wanchana S, Hashida M Yamashita F, Fujiwara S, Wanchana S, Hashida M Yamashita F, Fujiwara S, Wanchana S, Hashida M Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method. Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method. Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method. Journal of drug targeting, 14, 496-504 Journal of drug targeting, 14, 496-504 Journal of drug targeting, 14, 496-504 2006 英語 公開
Kawakami S, Opanasopit P, Yokoyama M, Chansri N, Yamamoto T, Okano T, Yamashita F, Hashida M Kawakami S, Opanasopit P, Yokoyama M, Chansri N, Yamamoto T, Okano T, Yamashita F, Hashida M Kawakami S, Opanasopit P, Yokoyama M, Chansri N, Yamamoto T, Okano T, Yamashita F, Hashida M Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration. Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration. Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration. Journal of pharmaceutical sciences, 94, 2606-2615 Journal of pharmaceutical sciences, 94, 2606-2615 Journal of pharmaceutical sciences, 94, 2606-2615 2005/12 英語 公開
Nishikawa M, Hyoudou K, Kobayashi Y, Umeyama Y, Takakura Y, Hashida M Nishikawa M, Hyoudou K, Kobayashi Y, Umeyama Y, Takakura Y, Hashida M Nishikawa M, Hyoudou K, Kobayashi Y, Umeyama Y, Takakura Y, Hashida M Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes. Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes. Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes. Journal of controlled release : official journal of the Controlled Release Society, 109, 101-107 Journal of controlled release : official journal of the Controlled Release Society, 109, 101-107 Journal of controlled release : official journal of the Controlled Release Society, 109, 101-107 2005/12 英語 公開
Kawakami S, Ito Y, Fumoto S, Yamashita F, Hashida M Kawakami S, Ito Y, Fumoto S, Yamashita F, Hashida M Kawakami S, Ito Y, Fumoto S, Yamashita F, Hashida M Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation. Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation. Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation. The journal of gene medicine, 7, 12, 1526-1533 The journal of gene medicine, 7, 12, 1526-1533 The journal of gene medicine, 7, 12, 1526-1533 2005/12 英語 公開
Hashida M Hashida M Hashida M [In-silico prediction of pharmacokinetic properties]. [In-silico prediction of pharmacokinetic properties]. [In-silico prediction of pharmacokinetic properties]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 125, 853-861 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 125, 853-861 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 125, 853-861 2005/11 日本語 公開
Hattori Y, Suzuki S, Kawakami S, Yamashita F, Hashida M Hattori Y, Suzuki S, Kawakami S, Yamashita F, Hashida M Hattori Y, Suzuki S, Kawakami S, Yamashita F, Hashida M The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route. The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route. The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route. Journal of controlled release : official journal of the Controlled Release Society, 108, 2-3, 484-495 Journal of controlled release : official journal of the Controlled Release Society, 108, 2-3, 484-495 Journal of controlled release : official journal of the Controlled Release Society, 108, 2-3, 484-495 2005/11 英語 公開
Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, Hashida M Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, Hashida M Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, Hashida M Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. The Journal of pharmacology and experimental therapeutics, 315, 2, 484-493 The Journal of pharmacology and experimental therapeutics, 315, 2, 484-493 The Journal of pharmacology and experimental therapeutics, 315, 2, 484-493 2005/11 英語 公開
Harada S, Yamashita F, Hashida M Harada S, Yamashita F, Hashida M Harada S, Yamashita F, Hashida M Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Drug metabolism and pharmacokinetics, 20, 331-336 Drug metabolism and pharmacokinetics, 20, 331-336 Drug metabolism and pharmacokinetics, 20, 331-336 2005/10 英語 公開
Managit C, Kawakami S, Yamashita F, Hashida M Managit C, Kawakami S, Yamashita F, Hashida M Managit C, Kawakami S, Yamashita F, Hashida M Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. Journal of pharmaceutical sciences, 94, 10, 2266-2275 Journal of pharmaceutical sciences, 94, 10, 2266-2275 Journal of pharmaceutical sciences, 94, 10, 2266-2275 2005/10 英語 公開
Higuchi Y, Kawakami S, Nishikawa M, Yamashita F, Hashida M Higuchi Y, Kawakami S, Nishikawa M, Yamashita F, Hashida M Higuchi Y, Kawakami S, Nishikawa M, Yamashita F, Hashida M Intracellular distribution of NFkappaB decoy and its inhibitory effect on TNFalpha production by LPS stimulated RAW 264.7 cells. Intracellular distribution of NFkappaB decoy and its inhibitory effect on TNFalpha production by LPS stimulated RAW 264.7 cells. Intracellular distribution of NFkappaB decoy and its inhibitory effect on TNFalpha production by LPS stimulated RAW 264.7 cells. Journal of controlled release : official journal of the Controlled Release Society, 107, 2, 373-382 Journal of controlled release : official journal of the Controlled Release Society, 107, 2, 373-382 Journal of controlled release : official journal of the Controlled Release Society, 107, 2, 373-382 2005/10 英語 公開
Yeeprae W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Yeeprae W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Yeeprae W, Kawakami S, Higuchi Y, Yamashita F, Hashida M Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice. Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice. Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice. Journal of drug targeting, 13, 479-487 Journal of drug targeting, 13, 479-487 Journal of drug targeting, 13, 479-487 2005/09 英語 公開
Arakawa Y, Kawakami S, Yamashita F, Hashida M Arakawa Y, Kawakami S, Yamashita F, Hashida M Arakawa Y, Kawakami S, Yamashita F, Hashida M Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Biological & pharmaceutical bulletin, 28, 9, 1679-1683 Biological & pharmaceutical bulletin, 28, 9, 1679-1683 Biological & pharmaceutical bulletin, 28, 9, 1679-1683 2005/09 英語 公開
Managit C, Kawakami S, Yamashita F, Hashida M Managit C, Kawakami S, Yamashita F, Hashida M Managit C, Kawakami S, Yamashita F, Hashida M Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. International journal of pharmaceutics, 301, 1-2, 255-261 International journal of pharmaceutics, 301, 1-2, 255-261 International journal of pharmaceutics, 301, 1-2, 255-261 2005/09 英語 公開
Katsumi H, Nishikawa M, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yamashita F, Hashida M Katsumi H, Nishikawa M, Yamashita F, Hashida M Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-Nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo. Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-Nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo. Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-Nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo. The Journal of pharmacology and experimental therapeutics, 314, 3, 1117-1124 The Journal of pharmacology and experimental therapeutics, 314, 3, 1117-1124 The Journal of pharmacology and experimental therapeutics, 314, 3, 1117-1124 2005/09 英語 公開
Hashida M, Kawakami S, Yamashita F Hashida M, Kawakami S, Yamashita F Hashida M, Kawakami S, Yamashita F Lipid carrier systems for targeted drug and gene delivery. Lipid carrier systems for targeted drug and gene delivery. Lipid carrier systems for targeted drug and gene delivery. Chemical & pharmaceutical bulletin, 53, 8, 871-880 Chemical & pharmaceutical bulletin, 53, 8, 871-880 Chemical & pharmaceutical bulletin, 53, 8, 871-880 2005/08 英語 公開
Thanaketpaisarn O, Nishikawa M, Yamashita F, Hashida M Thanaketpaisarn O, Nishikawa M, Yamashita F, Hashida M Thanaketpaisarn O, Nishikawa M, Yamashita F, Hashida M Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. Pharmaceutical research, 22, 6, 883-891 Pharmaceutical research, 22, 6, 883-891 Pharmaceutical research, 22, 6, 883-891 2005/06 英語 公開
Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Theoretical considerations involving the pharmacokinetics of plasmid DNA. Theoretical considerations involving the pharmacokinetics of plasmid DNA. Theoretical considerations involving the pharmacokinetics of plasmid DNA. Advanced drug delivery reviews, 57, 5, 675-688 Advanced drug delivery reviews, 57, 5, 675-688 Advanced drug delivery reviews, 57, 5, 675-688 2005/04 英語 公開
Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M Cationic charge-dependent hepatic delivery of amidated serum albumin. Cationic charge-dependent hepatic delivery of amidated serum albumin. Cationic charge-dependent hepatic delivery of amidated serum albumin. Journal of controlled release : official journal of the Controlled Release Society, 102, 3, 583-594 Journal of controlled release : official journal of the Controlled Release Society, 102, 3, 583-594 Journal of controlled release : official journal of the Controlled Release Society, 102, 3, 583-594 2005/02 英語 公開
Harada S, Nakada Y, Yamashita F, Hashida M Harada S, Nakada Y, Yamashita F, Hashida M Harada S, Nakada Y, Yamashita F, Hashida M Biopharmaceutical considerations on antihistamine effects of topically administered emedastine. Biopharmaceutical considerations on antihistamine effects of topically administered emedastine. Biopharmaceutical considerations on antihistamine effects of topically administered emedastine. Journal of pharmaceutical sciences, 94, 1, 17-24 Journal of pharmaceutical sciences, 94, 1, 17-24 Journal of pharmaceutical sciences, 94, 1, 17-24 2005/01 英語 公開
Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Nishikawa M, Takakura Y, Hashida M Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine. Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine. Pharmacokinetics of Plasmid DNA-Based Non-viral Gene Medicine. Advances in genetics, 53PA, 47-68 Advances in genetics, 53PA, 47-68 Advances in genetics, 53PA, 47-68 2005 英語 公開
Nagayoshi K, Nemoto T, Yokoyama S, Yamashita F, Hashida M Nagayoshi K, Nemoto T, Yokoyama S, Yamashita F, Hashida M Nagayoshi K, Nemoto T, Yokoyama S, Yamashita F, Hashida M Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Drug metabolism and pharmacokinetics, 19, 6, 407-412 Drug metabolism and pharmacokinetics, 19, 6, 407-412 Drug metabolism and pharmacokinetics, 19, 6, 407-412 2004/12 英語 公開
Higuchi Y, Nishikawa M, Kawakami S, Yamashita F, Hashida M Higuchi Y, Nishikawa M, Kawakami S, Yamashita F, Hashida M Higuchi Y, Nishikawa M, Kawakami S, Yamashita F, Hashida M Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells. Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells. Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells. International journal of pharmaceutics, 287, 1-2, 147-154 International journal of pharmaceutics, 287, 1-2, 147-154 International journal of pharmaceutics, 287, 1-2, 147-154 2004/12 英語 公開
Wanchana S, Yamashita F, Hara H, Fujiwara S, Akamatsu M, Hashida M Wanchana S, Yamashita F, Hara H, Fujiwara S, Akamatsu M, Hashida M Wanchana S, Yamashita F, Hara H, Fujiwara S, Akamatsu M, Hashida M Two- and three-dimensional QSAR of carrier-mediated transport of beta-lactam antibiotics in Caco-2 cells. Two- and three-dimensional QSAR of carrier-mediated transport of beta-lactam antibiotics in Caco-2 cells. Two- and three-dimensional QSAR of carrier-mediated transport of beta-lactam antibiotics in Caco-2 cells. Journal of pharmaceutical sciences, 93, 12, 3057-3065 Journal of pharmaceutical sciences, 93, 12, 3057-3065 Journal of pharmaceutical sciences, 93, 12, 3057-3065 2004/12 英語 公開
Hyoudou K, Nishikawa M, Umeyama Y, Kobayashi Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Umeyama Y, Kobayashi Y, Yamashita F, Hashida M Hyoudou K, Nishikawa M, Umeyama Y, Kobayashi Y, Yamashita F, Hashida M Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells. Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells. Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 22, 7685-7691 Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 22, 7685-7691 Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 22, 7685-7691 2004/11 英語 公開
Yamashita F, Hashida M Yamashita F, Hashida M Yamashita F, Hashida M In silico approaches for predicting ADME properties of drugs. In silico approaches for predicting ADME properties of drugs. In silico approaches for predicting ADME properties of drugs. Drug metabolism and pharmacokinetics, 19, 5, 327-338 Drug metabolism and pharmacokinetics, 19, 5, 327-338 Drug metabolism and pharmacokinetics, 19, 5, 327-338 2004/10 英語 公開
Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Molecular therapy : the journal of the American Society of Gene Therapy, 10, 4, 719-729 Molecular therapy : the journal of the American Society of Gene Therapy, 10, 4, 719-729 Molecular therapy : the journal of the American Society of Gene Therapy, 10, 4, 719-729 2004/10 英語 公開
Nakamura M, Yamaguchi S, Watanabe Y, Yamashita F, Takakura Y, Hashida M Nakamura M, Yamaguchi S, Watanabe Y, Yamashita F, Takakura Y, Hashida M Nakamura M, Yamaguchi S, Watanabe Y, Yamashita F, Takakura Y, Hashida M Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells. Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells. Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells. Biological & pharmaceutical bulletin, 27, 9, 1441-1443 Biological & pharmaceutical bulletin, 27, 9, 1441-1443 Biological & pharmaceutical bulletin, 27, 9, 1441-1443 2004/09 英語 公開
Katsumi H, Nishikawa M, Ma SF, Yamashita F, Hashida M Katsumi H, Nishikawa M, Ma SF, Yamashita F, Hashida M Katsumi H, Nishikawa M, Ma SF, Yamashita F, Hashida M Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: delivery of nitric oxide in vivo. Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: delivery of nitric oxide in vivo. Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: delivery of nitric oxide in vivo. Journal of pharmaceutical sciences, 93, 9, 2343-2352 Journal of pharmaceutical sciences, 93, 9, 2343-2352 Journal of pharmaceutical sciences, 93, 9, 2343-2352 2004/09 英語 公開
Yamada M, Nishikawa M, Kawakami S, Hattori Y, Nakano T, Yamashita F, Hashida M Yamada M, Nishikawa M, Kawakami S, Hattori Y, Nakano T, Yamashita F, Hashida M Yamada M, Nishikawa M, Kawakami S, Hattori Y, Nakano T, Yamashita F, Hashida M Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice. Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice. Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice. Journal of controlled release : official journal of the Controlled Release Society, 98, 1, 157-167 Journal of controlled release : official journal of the Controlled Release Society, 98, 1, 157-167 Journal of controlled release : official journal of the Controlled Release Society, 98, 1, 157-167 2004/07 英語 公開
Ishida E, Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Ishida E, Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Ishida E, Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Pharmaceutical research, 21, 6, 932-939 Pharmaceutical research, 21, 6, 932-939 Pharmaceutical research, 21, 6, 932-939 2004/06 英語 公開
Furumoto K, Nagayama S, Ogawara K, Takakura Y, Hashida M, Higaki K, Kimura T Furumoto K, Nagayama S, Ogawara K, Takakura Y, Hashida M, Higaki K, Kimura T Furumoto K, Nagayama S, Ogawara K, Takakura Y, Hashida M, Higaki K, Kimura T Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor. Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor. Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor. Journal of controlled release : official journal of the Controlled Release Society, 97, 1, 133-141 Journal of controlled release : official journal of the Controlled Release Society, 97, 1, 133-141 Journal of controlled release : official journal of the Controlled Release Society, 97, 1, 133-141 2004/05 英語 公開
Hattori Y, Kawakami S, Suzuki S, Yamashita F, Hashida M Hattori Y, Kawakami S, Suzuki S, Yamashita F, Hashida M Hattori Y, Kawakami S, Suzuki S, Yamashita F, Hashida M Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice. Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice. Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice. Biochemical and biophysical research communications, 317, 4, 992-999 Biochemical and biophysical research communications, 317, 4, 992-999 Biochemical and biophysical research communications, 317, 4, 992-999 2004/05 英語 公開
Nakamura M, Maruyama M, Yamashita F, Takakura Y, Hashida M, Watanabe Y Nakamura M, Maruyama M, Yamashita F, Takakura Y, Hashida M, Watanabe Y Nakamura M, Maruyama M, Yamashita F, Takakura Y, Hashida M, Watanabe Y Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells. Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells. Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells. Biological & pharmaceutical bulletin, 27, 3, 411-414 Biological & pharmaceutical bulletin, 27, 3, 411-414 Biological & pharmaceutical bulletin, 27, 3, 411-414 2004/03 英語 公開
Nishikawa M, Tamada A, Hyoudou K, Umeyama Y, Takahashi Y, Kobayashi Y, Kumai H, Ishida E, Staud F, Yabe Y, Takakura Y, Yamashita F, Hashida M Nishikawa M, Tamada A, Hyoudou K, Umeyama Y, Takahashi Y, Kobayashi Y, Kumai H, Ishida E, Staud F, Yabe Y, Takakura Y, Yamashita F, Hashida M Nishikawa M, Tamada A, Hyoudou K, Umeyama Y, Takahashi Y, Kobayashi Y, Kumai H, Ishida E, Staud F, Yabe Y, Takakura Y, Yamashita F, Hashida M Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. Clinical & experimental metastasis, 21, 3, 213-221 Clinical & experimental metastasis, 21, 3, 213-221 Clinical & experimental metastasis, 21, 3, 213-221 2004 英語 公開
Verbaan F, van Dam I, Takakura Y, Hashida M, Hennink W, Storm G, Oussoren C Verbaan F, van Dam I, Takakura Y, Hashida M, Hennink W, Storm G, Oussoren C Verbaan F, van Dam I, Takakura Y, Hashida M, Hennink W, Storm G, Oussoren C Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20, 4-5, 419-427 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20, 4-5, 419-427 European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 20, 4-5, 419-427 2003/12 英語 公開
Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M Targeted and sustained drug delivery using PEGylated galactosylated liposomes. Targeted and sustained drug delivery using PEGylated galactosylated liposomes. Targeted and sustained drug delivery using PEGylated galactosylated liposomes. International journal of pharmaceutics, 266, 1-2, 77-84 International journal of pharmaceutics, 266, 1-2, 77-84 International journal of pharmaceutics, 266, 1-2, 77-84 2003/11 英語 公開
Fujiwara S, Yamashita F, Hashida M Fujiwara S, Yamashita F, Hashida M Fujiwara S, Yamashita F, Hashida M QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept. QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept. QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept. Journal of pharmaceutical sciences, 92, 10, 1939-1946 Journal of pharmaceutical sciences, 92, 10, 1939-1946 Journal of pharmaceutical sciences, 92, 10, 1939-1946 2003/10 英語 公開
Wanchana S, Yamashita F, Hashida M Wanchana S, Yamashita F, Hashida M Wanchana S, Yamashita F, Hashida M QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method. QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method. QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method. Pharmaceutical research, 20, 9, 1401-1408 Pharmaceutical research, 20, 9, 1401-1408 Pharmaceutical research, 20, 9, 1401-1408 2003/09 英語 公開
Nishikawa M, Nakano T, Okabe T, Hamaguchi N, Yamasaki Y, Takakura Y, Yamashita F, Hashida M Nishikawa M, Nakano T, Okabe T, Hamaguchi N, Yamasaki Y, Takakura Y, Yamashita F, Hashida M Nishikawa M, Nakano T, Okabe T, Hamaguchi N, Yamasaki Y, Takakura Y, Yamashita F, Hashida M Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study. Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study. Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study. Bioconjugate chemistry, 14, 5, 955-961 Bioconjugate chemistry, 14, 5, 955-961 Bioconjugate chemistry, 14, 5, 955-961 2003/09 英語 公開
Yamashita F, Hashida M Yamashita F, Hashida M Yamashita F, Hashida M Mechanistic and empirical modeling of skin permeation of drugs. Mechanistic and empirical modeling of skin permeation of drugs. Mechanistic and empirical modeling of skin permeation of drugs. Advanced drug delivery reviews, 55, 9, 1185-1199 Advanced drug delivery reviews, 55, 9, 1185-1199 Advanced drug delivery reviews, 55, 9, 1185-1199 2003/09 英語 公開
Sakurai F, Terada T, Maruyama M, Watanabe Y, Yamashita F, Takakura Y, Hashida M Sakurai F, Terada T, Maruyama M, Watanabe Y, Yamashita F, Takakura Y, Hashida M Sakurai F, Terada T, Maruyama M, Watanabe Y, Yamashita F, Takakura Y, Hashida M Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model. Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model. Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model. Cancer gene therapy, 10, 9, 661-668 Cancer gene therapy, 10, 9, 661-668 Cancer gene therapy, 10, 9, 661-668 2003/09 英語 公開
Kawase A, Nomura T, Yasuda K, Kobayashi N, Hashida M, Takakura Y Kawase A, Nomura T, Yasuda K, Kobayashi N, Hashida M, Takakura Y Kawase A, Nomura T, Yasuda K, Kobayashi N, Hashida M, Takakura Y Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice. Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice. Disposition and gene expression characteristics in solid tumors and skeletal muscle after direct injection of naked plasmid DNA in mice. Journal of pharmaceutical sciences, 92, 6, 1295-1304 Journal of pharmaceutical sciences, 92, 6, 1295-1304 Journal of pharmaceutical sciences, 92, 6, 1295-1304 2003/06 英語 公開
Wu X, Yamashita F, Hashida M, Chen X, Hu Z Wu X, Yamashita F, Hashida M, Chen X, Hu Z Wu X, Yamashita F, Hashida M, Chen X, Hu Z Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Talanta, 59, 965-971 Talanta, 59, 965-971 Talanta, 59, 965-971 2003/04 英語 公開
Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, Hashida M Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, Hashida M Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, Hashida M Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Molecular therapy : the journal of the American Society of Gene Therapy, 7, 2, 254-261 Molecular therapy : the journal of the American Society of Gene Therapy, 7, 2, 254-261 Molecular therapy : the journal of the American Society of Gene Therapy, 7, 2, 254-261 2003/02 英語 公開
Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Drug metabolism and pharmacokinetics, 18, 4, 230-237 Drug metabolism and pharmacokinetics, 18, 4, 230-237 Drug metabolism and pharmacokinetics, 18, 4, 230-237 2003 英語 公開
Nishikawa M, Kawakami S, Yamashita F, Hashida M Nishikawa M, Kawakami S, Yamashita F, Hashida M Nishikawa M, Kawakami S, Yamashita F, Hashida M Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer. Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer. Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer. Methods in enzymology, 373, 384-399 Methods in enzymology, 373, 384-399 Methods in enzymology, 373, 384-399 2003 英語 公開
Yabe Y, Kobayashi N, Nishikawa M, Mihara K, Yamashita F, Takakura Y, Hashida M Yabe Y, Kobayashi N, Nishikawa M, Mihara K, Yamashita F, Takakura Y, Hashida M Yabe Y, Kobayashi N, Nishikawa M, Mihara K, Yamashita F, Takakura Y, Hashida M Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver. Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver. Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver. Pharmaceutical research, 19, 12, 1815-1821 Pharmaceutical research, 19, 12, 1815-1821 Pharmaceutical research, 19, 12, 1815-1821 2002/12 英語 公開
Murao A, Nishikawa M, Managit C, Wong J, Kawakami S, Yamashita F, Hashida M Murao A, Nishikawa M, Managit C, Wong J, Kawakami S, Yamashita F, Hashida M Murao A, Nishikawa M, Managit C, Wong J, Kawakami S, Yamashita F, Hashida M Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: effect of lipid composition. Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: effect of lipid composition. Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: effect of lipid composition. Pharmaceutical research, 19, 12, 1808-1814 Pharmaceutical research, 19, 12, 1808-1814 Pharmaceutical research, 19, 12, 1808-1814 2002/12 英語 公開
Yamashita F, Wanchana S, Hashida M Yamashita F, Wanchana S, Hashida M Yamashita F, Wanchana S, Hashida M Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method. Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method. Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method. Journal of pharmaceutical sciences, 91, 10, 2230-2239 Journal of pharmaceutical sciences, 91, 10, 2230-2239 Journal of pharmaceutical sciences, 91, 10, 2230-2239 2002/10 英語 公開
Akazawa Y, Kawaguchi H, Funahashi M, Watanabe Y, Yamaoka K, Hashida M, Takakura Y Akazawa Y, Kawaguchi H, Funahashi M, Watanabe Y, Yamaoka K, Hashida M, Takakura Y Akazawa Y, Kawaguchi H, Funahashi M, Watanabe Y, Yamaoka K, Hashida M, Takakura Y Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat hepatocytes. Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat hepatocytes. Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat hepatocytes. Journal of pharmaceutical sciences, 91, 10, 2110-2115 Journal of pharmaceutical sciences, 91, 10, 2110-2115 Journal of pharmaceutical sciences, 91, 10, 2110-2115 2002/10 英語 公開
Furumoto K, Ogawara K, Nagayama S, Takakura Y, Hashida M, Higaki K, Kimura T Furumoto K, Ogawara K, Nagayama S, Takakura Y, Hashida M, Higaki K, Kimura T Furumoto K, Ogawara K, Nagayama S, Takakura Y, Hashida M, Higaki K, Kimura T Important role of serum proteins associated on the surface of particles in their hepatic disposition. Important role of serum proteins associated on the surface of particles in their hepatic disposition. Important role of serum proteins associated on the surface of particles in their hepatic disposition. Journal of controlled release : official journal of the Controlled Release Society, 83, 1, 89-96 Journal of controlled release : official journal of the Controlled Release Society, 83, 1, 89-96 Journal of controlled release : official journal of the Controlled Release Society, 83, 1, 89-96 2002/09 英語 公開
Nakanishi K, Watanabe Y, Maruyama M, Yamashita F, Takakura Y, Hashida M Nakanishi K, Watanabe Y, Maruyama M, Yamashita F, Takakura Y, Hashida M Nakanishi K, Watanabe Y, Maruyama M, Yamashita F, Takakura Y, Hashida M Secretion polarity of interferon-beta in epithelial cell lines. Secretion polarity of interferon-beta in epithelial cell lines. Secretion polarity of interferon-beta in epithelial cell lines. Archives of biochemistry and biophysics, 402, 2, 201-207 Archives of biochemistry and biophysics, 402, 2, 201-207 Archives of biochemistry and biophysics, 402, 2, 201-207 2002/06 英語 公開
Nishikawa M, Tamada A, Kumai H, Yamashita F, Hashida M Nishikawa M, Tamada A, Kumai H, Yamashita F, Hashida M Nishikawa M, Tamada A, Kumai H, Yamashita F, Hashida M Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. International journal of cancer. Journal international du cancer, 99, 3, 474-479 International journal of cancer. Journal international du cancer, 99, 3, 474-479 International journal of cancer. Journal international du cancer, 99, 3, 474-479 2002/05 英語 公開
Yamasaki Y, Sumimoto K, Nishikawa M, Yamashita F, Yamaoka K, Hashida M, Takakura Y Yamasaki Y, Sumimoto K, Nishikawa M, Yamashita F, Yamaoka K, Hashida M, Takakura Y Yamasaki Y, Sumimoto K, Nishikawa M, Yamashita F, Yamaoka K, Hashida M, Takakura Y Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: importance of molecular size and negative charge density for in vivo recognition by receptors. Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: importance of molecular size and negative charge density for in vivo recognition by receptors. Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: importance of molecular size and negative charge density for in vivo recognition by receptors. The Journal of pharmacology and experimental therapeutics, 301, 2, 467-477 The Journal of pharmacology and experimental therapeutics, 301, 2, 467-477 The Journal of pharmacology and experimental therapeutics, 301, 2, 467-477 2002/05 英語 公開
Yasuda K, Ogawa Y, Kishimoto M, Takagi T, Hashida M, Takakura Y Yasuda K, Ogawa Y, Kishimoto M, Takagi T, Hashida M, Takakura Y Yasuda K, Ogawa Y, Kishimoto M, Takagi T, Hashida M, Takakura Y Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes. Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes. Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes. Biochemical and biophysical research communications, 293, 1, 344-348 Biochemical and biophysical research communications, 293, 1, 344-348 Biochemical and biophysical research communications, 293, 1, 344-348 2002/04 英語 公開
Fujiwara S, Yamashita F, Hashida M Fujiwara S, Yamashita F, Hashida M Fujiwara S, Yamashita F, Hashida M Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network. Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network. Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network. International journal of pharmaceutics, 237, 95-105 International journal of pharmaceutics, 237, 95-105 International journal of pharmaceutics, 237, 95-105 2002/04 英語 公開
Opanasopit P, Sakai M, Nishikawa M, Kawakami S, Yamashita F, Hashida M Opanasopit P, Sakai M, Nishikawa M, Kawakami S, Yamashita F, Hashida M Opanasopit P, Sakai M, Nishikawa M, Kawakami S, Yamashita F, Hashida M Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers. Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers. Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers. Journal of controlled release : official journal of the Controlled Release Society, 80, 283-294 Journal of controlled release : official journal of the Controlled Release Society, 80, 283-294 Journal of controlled release : official journal of the Controlled Release Society, 80, 283-294 2002/04 英語 公開
Nishikawa M, Hasegawa S, Yamashita F, Takakura Y, Hashida M Nishikawa M, Hasegawa S, Yamashita F, Takakura Y, Hashida M Nishikawa M, Hasegawa S, Yamashita F, Takakura Y, Hashida M Electrical charge on protein regulates its absorption from the rat small intestine. Electrical charge on protein regulates its absorption from the rat small intestine. Electrical charge on protein regulates its absorption from the rat small intestine. American journal of physiology. Gastrointestinal and liver physiology, 282, G711-9 American journal of physiology. Gastrointestinal and liver physiology, 282, G711-9 American journal of physiology. Gastrointestinal and liver physiology, 282, G711-9 2002/04 英語 公開
Takakura Y, Nishikawa M, Yamashita F, Hashida M Takakura Y, Nishikawa M, Yamashita F, Hashida M Takakura Y, Nishikawa M, Yamashita F, Hashida M Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery. Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery. Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery. Journal of drug targeting, 10, 2, 99-104 Journal of drug targeting, 10, 2, 99-104 Journal of drug targeting, 10, 2, 99-104 2002/03 英語 公開
Lim CW, Fujiwara S, Yamashita F, Hashida M Lim CW, Fujiwara S, Yamashita F, Hashida M Lim CW, Fujiwara S, Yamashita F, Hashida M Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network. Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network. Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network. Biological & pharmaceutical bulletin, 25, 361-366 Biological & pharmaceutical bulletin, 25, 361-366 Biological & pharmaceutical bulletin, 25, 361-366 2002/03 英語 公開
Nishikawa M, Hashida M Nishikawa M, Hashida M Nishikawa M, Hashida M Nonviral approaches satisfying various requirements for effective in vivo gene therapy. Nonviral approaches satisfying various requirements for effective in vivo gene therapy. Nonviral approaches satisfying various requirements for effective in vivo gene therapy. Biological & pharmaceutical bulletin, 25, 275-283 Biological & pharmaceutical bulletin, 25, 275-283 Biological & pharmaceutical bulletin, 25, 275-283 2002/03 英語 公開
Yamashita F, Fujiwara S, Hashida M Yamashita F, Fujiwara S, Hashida M Yamashita F, Fujiwara S, Hashida M The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratory variable Caco-2 permeability. The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratory variable Caco-2 permeability. The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratory variable Caco-2 permeability. Journal of chemical information and computer sciences, 42, 408-413 Journal of chemical information and computer sciences, 42, 408-413 Journal of chemical information and computer sciences, 42, 408-413 2002/03 英語 公開
Takagi A, Yabe Y, Oka Y, Takakura Y, Hashida M Takagi A, Yabe Y, Oka Y, Takakura Y, Hashida M Takagi A, Yabe Y, Oka Y, Takakura Y, Hashida M Effect of co-administration of cationic macromolecules on the in vivo disposition and in situ renal disposition characteristics of rhIL-11. Effect of co-administration of cationic macromolecules on the in vivo disposition and in situ renal disposition characteristics of rhIL-11. Effect of co-administration of cationic macromolecules on the in vivo disposition and in situ renal disposition characteristics of rhIL-11. Drug metabolism and pharmacokinetics, 17, 2, 136-141 Drug metabolism and pharmacokinetics, 17, 2, 136-141 Drug metabolism and pharmacokinetics, 17, 2, 136-141 2002 英語 公開
Opanasopit P, Nishikawa M, Hashida M Opanasopit P, Nishikawa M, Hashida M Opanasopit P, Nishikawa M, Hashida M Factors affecting drug and gene delivery: effects of interaction with blood components. Factors affecting drug and gene delivery: effects of interaction with blood components. Factors affecting drug and gene delivery: effects of interaction with blood components. Critical reviews in therapeutic drug carrier systems, 19, 3, 191-233 Critical reviews in therapeutic drug carrier systems, 19, 3, 191-233 Critical reviews in therapeutic drug carrier systems, 19, 3, 191-233 2002 英語 公開
Kawakami S, Yamashita F, Nishida K, Nakamura J, Hashida M Kawakami S, Yamashita F, Nishida K, Nakamura J, Hashida M Kawakami S, Yamashita F, Nishida K, Nakamura J, Hashida M Glycosylated cationic liposomes for cell-selective gene delivery. Glycosylated cationic liposomes for cell-selective gene delivery. Glycosylated cationic liposomes for cell-selective gene delivery. Critical reviews in therapeutic drug carrier systems, 19, 2, 171-190 Critical reviews in therapeutic drug carrier systems, 19, 2, 171-190 Critical reviews in therapeutic drug carrier systems, 19, 2, 171-190 2002 英語 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
振津 尚夫, 高倉 喜信, 橋田 充, 藤田 卓也, 瀬崎 仁 振津 尚夫, 高倉 喜信, 橋田 充, 藤田 卓也, 瀬崎 仁 各種糖修飾superoxide dismutaseの肝障害抑制効果 各種糖修飾superoxide dismutaseの肝障害抑制効果 Drug Delivery System, 8, 1, 49-52 Drug Delivery System, 8, 1, 49-52 , 8, 1, 49-52 1993 公開
山下 富義, 小山 靖夫, 坂東 博人, 高倉 喜信, 橋田 充 山下 富義, 小山 靖夫, 坂東 博人, 高倉 喜信, 橋田 充 機構論に基づく吸収促進剤適用の最適化の試み 機構論に基づく吸収促進剤適用の最適化の試み Drug Delivery System, 8, 4, 243-250 Drug Delivery System, 8, 4, 243-250 , 8, 4, 243-250 1993 公開
Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs. Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs. Journal of Pharmaceutical Sciences, 90, 2, 105-113 , 90, 2, 105-113 Journal of Pharmaceutical Sciences, 90, 2, 105-113 2001 公開
In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein. In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein. American Journal of Physiology, 280, G879-G889 , 280, G879-G889 American Journal of Physiology, 280, G879-G889 2001 公開
Involvement of serum mannan binding proteins and mannose receptors in uptake of mannosylated liposomes by macrophagcs. Involvement of serum mannan binding proteins and mannose receptors in uptake of mannosylated liposomes by macrophagcs. Biochimica et Biophysica Acta., 1511, 134-145 , 1511, 134-145 Biochimica et Biophysica Acta., 1511, 134-145 2001 公開
Interaction between DNA -cationic liposome complexes and erythrocytes is an inportant factor in systemic gene transfer via the intravenous route in mice : The role of the neutral helper lipid. Interaction between DNA -cationic liposome complexes and erythrocytes is an inportant factor in systemic gene transfer via the intravenous route in mice : The role of the neutral helper lipid. Gene Therapy, 8, 9, 677-686 , 8, 9, 677-686 Gene Therapy, 8, 9, 677-686 2001 公開
Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting. Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting. Die Pharmazie, 55, 3, 202-205 , 55, 3, 202-205 Die Pharmazie, 55, 3, 202-205 2000 公開
Intratumoral pharmacokinetics of oligonucleotides in tissue-isolated tumor perfusion system. Intratumoral pharmacokinetics of oligonucleotides in tissue-isolated tumor perfusion system. Antisense and Nucleic Acid Drug Development, 10, 105-110 , 10, 105-110 Antisense and Nucleic Acid Drug Development, 10, 105-110 2000 公開
Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Journal of Drug Targeting, 7, 5, 363-371 , 7, 5, 363-371 Journal of Drug Targeting, 7, 5, 363-371 2000 公開
Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes. Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes. Gene Therapy, 7, 4, 292-299 , 7, 4, 292-299 Gene Therapy, 7, 4, 292-299 2000 公開
Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multifunctional gene delivery system. Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multifunctional gene delivery system. Gene Therapy, 7, 7, 548-555 , 7, 7, 548-555 Gene Therapy, 7, 7, 548-555 2000 公開
Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly (L-Lysine) in mice. Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly (L-Lysine) in mice. Journal of Drug Targeting, 8, 1, 29-38 , 8, 1, 29-38 Journal of Drug Targeting, 8, 1, 29-38 2000 公開
Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular and trafficking of plasmid DNA/ cationic liposome complexes and subsequent gene expression Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular and trafficking of plasmid DNA/ cationic liposome complexes and subsequent gene expression Journal of Controlled Release, 66, 2/3, 255-269 , 66, 2/3, 255-269 Journal of Controlled Release, 66, 2/3, 255-269 2000 公開
In vivo gene delivery to the liver using novel galactosylated cationic liposomes. In vivo gene delivery to the liver using novel galactosylated cationic liposomes. Pharmaceutical Research, 17, 3, 306-313 , 17, 3, 306-313 Pharmaceutical Research, 17, 3, 306-313 2000 公開
Targeted delivery of prostaglandin E1 to hepatocytes using galactosylated liposomes. Targeted delivery of prostaglandin E1 to hepatocytes using galactosylated liposomes. Journal of Drug Targeting, 8, 3, 137-142 , 8, 3, 137-142 Journal of Drug Targeting, 8, 3, 137-142 2000 公開
Biobistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biobistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochimica et Biophysica Acta., 1524, 2-3, 258-265 , 1524, 2-3, 258-265 Biochimica et Biophysica Acta., 1524, 2-3, 258-265 2000 公開
Stimulation side-dependent asymmetrical secretion of poly I : ploy C-induced interferon-β from polarized epithelial cell lines. Stimulation side-dependent asymmetrical secretion of poly I : ploy C-induced interferon-β from polarized epithelial cell lines. Biochemical and Biophysical Research Communications, 254, 1, 5-9 , 254, 1, 5-9 Biochemical and Biophysical Research Communications, 254, 1, 5-9 1999 公開
Gene expression and antitumor effects following direct interfern (IFN)-γ gene transter with naked plasmid DNA and DC-chol liposome complexes in mice. Gene expression and antitumor effects following direct interfern (IFN)-γ gene transter with naked plasmid DNA and DC-chol liposome complexes in mice. Gene Therapy, 6, 1, 121-129 , 6, 1, 121-129 Gene Therapy, 6, 1, 121-129 1999 公開
Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class A scavenger receptor knockout mice. Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class A scavenger receptor knockout mice. Pharmaceutical Research, 16, 4, 503-508 , 16, 4, 503-508 Pharmaceutical Research, 16, 4, 503-508 1999 公開
Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice. Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice. Biochimica et Biophysica Acta, 1426, 3, 420-428 , 1426, 3, 420-428 Biochimica et Biophysica Acta, 1426, 3, 420-428 1999 公開
Targeted delivery and improved therapeutic potential of catolase by chemical modification : combination with superoxide dismutase derivatives Targeted delivery and improved therapeutic potential of catolase by chemical modification : combination with superoxide dismutase derivatives Journal of Pharmacology and Experimental Therapeutics, 289, 2, 1176-1184 , 289, 2, 1176-1184 Journal of Pharmacology and Experimental Therapeutics, 289, 2, 1176-1184 1999 公開
Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1(Keratinocyte transglutaminase). Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1(Keratinocyte transglutaminase). Proceedings of the National Academy of Sciences of the United States of America, 95, 3, 1044-1049 , 95, 3, 1044-1049 Proceedings of the National Academy of Sciences of the United States of America, 95, 3, 1044-1049 1998 公開
Cellular uptake properties of oligonucleotides in LLC-PK, renal epithelial cells. Cellular uptake properties of oligonucleotides in LLC-PK, renal epithelial cells. Antisense and Nucleic Acid Drug Development, 8, 67-73 , 8, 67-73 Antisense and Nucleic Acid Drug Development, 8, 67-73 1998 公開
Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors. Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors. Pharmaceutical Research, 15, 1, 128-132 , 15, 1, 128-132 Pharmaceutical Research, 15, 1, 128-132 1998 公開
Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells. Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells. Biochemical and Biophysical Research Communications, 245, 1, 235-239 , 245, 1, 235-239 Biochemical and Biophysical Research Communications, 245, 1, 235-239 1998 公開
Involvement of specific mechanism in plasmid DNA uptake by mouse peritoneal macrophages. Involvement of specific mechanism in plasmid DNA uptake by mouse peritoneal macrophages. Biochemical and Biophysical Research Communications, 245, 3, 729-733 , 245, 3, 729-733 Biochemical and Biophysical Research Communications, 245, 3, 729-733 1998 公開
Targeted delivery of plasmid DNA to hepatocytes in vivo : optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine)complexes by controlling their physicochemical properties. Targeted delivery of plasmid DNA to hepatocytes in vivo : optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine)complexes by controlling their physicochemical properties. Journal of Pharmacology and Experimental Therapeutics, 287, 1, 408-415 , 287, 1, 408-415 Journal of Pharmacology and Experimental Therapeutics, 287, 1, 408-415 1998 公開
Theoretical design of prodrug-enhancer combination based on a skin diffusion model : Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one. Theoretical design of prodrug-enhancer combination based on a skin diffusion model : Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one. Pharmaceutical Research, 13, 3, 427-432 , 13, 3, 427-432 Pharmaceutical Research, 13, 3, 427-432 1996 公開
Disposition of oligonucleotides in isolated perfused rat kidny : Involvement of scavenger receptors in their renal uptake. Disposition of oligonucleotides in isolated perfused rat kidny : Involvement of scavenger receptors in their renal uptake. The Journal of Pharmacology and Experimental Therapeutics, 279, 1, 284-290 , 279, 1, 284-290 The Journal of Pharmacology and Experimental Therapeutics, 279, 1, 284-290 1996 公開
Pharmacokinetic analysis of drug disposition affter intratumoral injection in a tissue-isolated tumor perfusion system. Pharmacokinetic analysis of drug disposition affter intratumoral injection in a tissue-isolated tumor perfusion system. Pharmaceutical Research, 13, 10, 1438-1444 , 13, 10, 1438-1444 Pharmaceutical Research, 13, 10, 1438-1444 1996 公開
Pharmacokinetics and targeted delivery of proteins and genes. Pharmacokinetics and targeted delivery of proteins and genes. Journal of Controlled Release, 41, 1/2, 91-97 , 41, 1/2, 91-97 Journal of Controlled Release, 41, 1/2, 91-97 1996 公開
Macromolecular drug carrier systems in cancer chemotherapy : macromolecular prodrugs Macromolecular drug carrier systems in cancer chemotherapy : macromolecular prodrugs Critical Reviews in Oncology/Hematology, 18, 207 , 18, 207 Critical Reviews in Oncology/Hematology, 18, 207 1995 公開
Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties American Journal of Physiology, 268, G849 , 268, G849 American Journal of Physiology, 268, G849 1995 公開
Stability and pharmacokinetics of oligonucleotides modified at terminal linkages in mice Stability and pharmacokinetics of oligonucleotides modified at terminal linkages in mice Antisense Research and Development, 5, 115 , 5, 115 Antisense Research and Development, 5, 115 1995 公開
Pharmacokinetics in design of polymeric drug delivery systems Pharmacokinetics in design of polymeric drug delivery systems Journal of Controlled Release, 31, 2, 163-171 , 31, 2, 163-171 Journal of Controlled Release, 31, 2, 163-171 1994 公開
Control of the disposition profiles of Proteins in the kidney via chemical modification Control of the disposition profiles of Proteins in the kidney via chemical modification Journal of Controlled Release, 28, 1/3, 111-119 , 28, 1/3, 111-119 Journal of Controlled Release, 28, 1/3, 111-119 1994 公開
Pharmacokinetics of succinylated proteins and dextran sulfate in mice : Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors Pharmacokinetics of succinylated proteins and dextran sulfate in mice : Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors International Journal of Pharmaceutics, 105, 1, 19-29 , 105, 1, 19-29 International Journal of Pharmaceutics, 105, 1, 19-29 1994 公開
Targeted delivery of superoxide dismutase to macrophages via mannose receptor-mediated mechanism Targeted delivery of superoxide dismutase to macrophages via mannose receptor-mediated mechanism Biochemical Pharmacology, 47, 5, 853-858 , 47, 5, 853-858 Biochemical Pharmacology, 47, 5, 853-858 1994 公開
Improvement of therapeutic effect of human recombinant superoxide dismutase on ischemic acute renal failure in the rat via cationization and conjugation with polyethylene glycol Improvement of therapeutic effect of human recombinant superoxide dismutase on ischemic acute renal failure in the rat via cationization and conjugation with polyethylene glycol Journal of Drug Targeting, 2, 317 , 2, 317 Journal of Drug Targeting, 2, 317 1994 公開
Kiyoshi MIHARA, Mihoko MORI, Takami HOJO, Yoshinobu TAKAKURA, Hitoshi SEZAKI, Mitsuru HASHIDA Kiyoshi MIHARA, Mihoko MORI, Takami HOJO, Yoshinobu TAKAKURA, Hitoshi SEZAKI, Mitsuru HASHIDA Disposition characteristics of model macromolecules in the perfused rat Kidney. Disposition characteristics of model macromolecules in the perfused rat Kidney. Biological & Pharmaceutical Bulletin, 16, 2, 158-162 , 16, 2, 158-162 Biological & Pharmaceutical Bulletin, 16, 2, 158-162 1993 公開
Estimation of a concentration profile of acyclovir in the skin after topical administration. Estimation of a concentration profile of acyclovir in the skin after topical administration. International Journal of Pharmaceutics, 89, 3, 199-206 , 89, 3, 199-206 International Journal of Pharmaceutics, 89, 3, 199-206 1993 公開
Takahiro MORITA, Akira YAMAMOTO, Mitsuru HASHIDA, Hitoshi SEZAKI Takahiro MORITA, Akira YAMAMOTO, Mitsuru HASHIDA, Hitoshi SEZAKI Effects of various absorption promoters on pulmonary absorption of drugs with different molecular weights. Effects of various absorption promoters on pulmonary absorption of drugs with different molecular weights. Biological and Pharmaceutical Bulletin, 16, 3, 259-262 , 16, 3, 259-262 Biological and Pharmaceutical Bulletin, 16, 3, 259-262 1993 公開
Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum : dose-dependent effect of 1-geranylazacycloheptan-2-one-drug with different lipophilicities. Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum : dose-dependent effect of 1-geranylazacycloheptan-2-one-drug with different lipophilicities. Biological and Pharmaceutical Bulletin, 16, 7, 690-697 , 16, 7, 690-697 Biological and Pharmaceutical Bulletin, 16, 7, 690-697 1993 公開
Effect of absorption promoters on the nasal absorption of drugs with various molecular weights. Effect of absorption promoters on the nasal absorption of drugs with various molecular weights. International Journal of Pharmaceutics, 93,91-99 , 93,91-99 International Journal of Pharmaceutics, 93,91-99 1993 公開
Disposition characteristics of protein drugs in the perfused rat kidney. Disposition characteristics of protein drugs in the perfused rat kidney. Pharmaceutical Research, 10, 6, 823-827 , 10, 6, 823-827 Pharmaceutical Research, 10, 6, 823-827 1993 公開
Controlled biodistribution of highly lipophilic drugs with various parenteral formulations. Controlled biodistribution of highly lipophilic drugs with various parenteral formulations. Journal of Drug Targeting, 1, 2, 117-124 , 1, 2, 117-124 Journal of Drug Targeting, 1, 2, 117-124 1993 公開
Synthesis of pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting Synthesis of pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting Pharmaceutical Research, 10, 9, 1253-1261 , 10, 9, 1253-1261 Pharmaceutical Research, 10, 9, 1253-1261 1993 公開
Specific uptake of succinylated proteins via a scavenger receptor-mediated mechanism in cultured brain microvessel endothelial cells. Specific uptake of succinylated proteins via a scavenger receptor-mediated mechanism in cultured brain microvessel endothelial cells. Biochemical and Biophysical Research Communications, 196, 1, 18-24 , 196, 1, 18-24 Biochemical and Biophysical Research Communications, 196, 1, 18-24 1993 公開
Drug Targeting with Macromolecular Carrier Systems in "Perspectives in Medicinal Chemistry" Drug Targeting with Macromolecular Carrier Systems in "Perspectives in Medicinal Chemistry" Verlag Helvetica Chimica Acta(basel), 545-558 , 545-558 Verlag Helvetica Chimica Acta(basel), 545-558 1993 公開
Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation Cancer Research, 52, 16 , 52, 16 Cancer Research, 52, 16 1992 公開
Effect of chronic administration of phenobarbital on the hepatobiliary transport of phanol red : Assessment by statistical moment analysis Effect of chronic administration of phenobarbital on the hepatobiliary transport of phanol red : Assessment by statistical moment analysis Pharmaceutical Research, 9, 7, 908-914 , 9, 7, 908-914 Pharmaceutical Research, 9, 7, 908-914 1992 公開
Demonstration of the receptor-mediated hepatic uptake of dextran in mice Demonstration of the receptor-mediated hepatic uptake of dextran in mice International Journal of Pharmaceutics, 44 , 44 International Journal of Pharmaceutics, 44 1992 公開
Pharmacokinetic analysis of drug absorption from muscle based on physiological diffusion model : Effect of molecular size on absorption Pharmacokinetic analysis of drug absorption from muscle based on physiological diffusion model : Effect of molecular size on absorption Pharmaceutical Research, 9, 2, 161-168 , 9, 2, 161-168 Pharmaceutical Research, 9, 2, 161-168 1992 公開
Preparation and properties of the immunoconjugate composed of anti-human colon cancer monoclonal antibody and mitomycin C-dextran conjugate Preparation and properties of the immunoconjugate composed of anti-human colon cancer monoclonal antibody and mitomycin C-dextran conjugate Bioconjugate Chemistry, 3 , 3 Bioconjugate Chemistry, 3 1992 公開
Pharmacokinetic analysis of uptake process of lactosaminated albumin in the rat liver constant infusion experiment Pharmacokinetic analysis of uptake process of lactosaminated albumin in the rat liver constant infusion experiment International Journal of Pharmaceutics, 80, 2, 3 , 80, 2, 3 International Journal of Pharmaceutics, 80, 2, 3 1992 公開
Permeability of macromolecules in cultured endothelial and tumor cell layers on microporous membranes Permeability of macromolecules in cultured endothelial and tumor cell layers on microporous membranes International Journal of Pharmaceutics, 78, 2, 3 , 78, 2, 3 International Journal of Pharmaceutics, 78, 2, 3 1992 公開
Takuya FUJITA, Yoshihisa YASUDA, Yoshinobu TAKAKURA, Mitsuru HASHIDA, Hitoshi SEZAKI Takuya FUJITA, Yoshihisa YASUDA, Yoshinobu TAKAKURA, Mitsuru HASHIDA, Hitoshi SEZAKI Tissue distribution of <sup>111</sup>In-labeled uricase conjugated with charged dextrans and polyethylene glycol Tissue distribution of <sup>111</sup>In-labeled uricase conjugated with charged dextrans and polyethylene glycol Journal of Pharmacobio- Dynamics, 14, 11, 623-629 , 14, 11, 623-629 Journal of Pharmacobio- Dynamics, 14, 11, 623-629 1991 公開

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タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
医療イノベーションを支えるサイエンス 医療イノベーションを支えるサイエンス 日本薬剤学会第31年会 日本薬剤学会第31年会 2016/05/19 日本語 口頭発表(一般) 公開
薬の体内動態と標的指向化:ドラッグデリバリーシステム 薬の体内動態と標的指向化:ドラッグデリバリーシステム 平成27年度大阪府立高等学校GLHS10校 京都大学キャンパスガイド分科会 平成27年度大阪府立高等学校GLHS10校 京都大学キャンパスガイド分科会 2015/12/12 日本語 公開講演、セミナー、チュートリアル、講習、講義 公開
レギュラトリーサイエンスの動向とセルフメディケーション レギュラトリーサイエンスの動向とセルフメディケーション 日本薬学会レギュラトリーサイエンス部会 第12回医薬品レギュラトリーサイエンスフォーラム 日本薬学会レギュラトリーサイエンス部会 第12回医薬品レギュラトリーサイエンスフォーラム 2015/12/08 日本語 口頭発表(招待・特別) 公開
薬物投与技術の進歩と将来の医療 薬物投与技術の進歩と将来の医療 第25回日本医療薬学会年会 第25回日本医療薬学会年会 2015/11/21 日本語 口頭発表(招待・特別) 公開
第17改正日本薬局方と最近の薬事行政に関する話題 第17改正日本薬局方と最近の薬事行政に関する話題 平成27年度日本薬局方教科担当教員会議 平成27年度日本薬局方教科担当教員会議 2015/11/07 日本語 口頭発表(招待・特別) 公開
薬事行政をめぐる最近の話題 薬事行政をめぐる最近の話題 平成27年度薬剤学教科担当教員会議 平成27年度薬剤学教科担当教員会議 2015/08/28 日本語 口頭発表(招待・特別) 公開
DDS:基礎から開発まで DDS:基礎から開発まで 第2回LUTS治療薬 薬物動態を考える会 第2回LUTS治療薬 薬物動態を考える会 2015/06/14 日本語 口頭発表(招待・特別) 公開
薬学の動向:教育から薬事まで 薬学の動向:教育から薬事まで レギュラトリーサイエンス講演会 レギュラトリーサイエンス講演会 2015/02/21 日本語 口頭発表(基調) 公開
DDS(ドラッグデリバリーシステム) DDS(ドラッグデリバリーシステム) 第5回京都コモンズ会員セミナー 第5回京都コモンズ会員セミナー 2015/01/28 日本語 口頭発表(招待・特別) 公開
Recent advances in dug delivery: Design and evaluation Recent advances in dug delivery: Design and evaluation Recent advances in dug delivery: Design and evaluation Pharma Tech 2014 Pharma Tech 2014 Pharma Tech 2014 2014/12/01 英語 口頭発表(招待・特別) 公開
薬学の動向-教育・職能・薬事から製剤開発まで 薬学の動向-教育・職能・薬事から製剤開発まで 第76回九州山口薬学大会 第76回九州山口薬学大会 2014/11/23 日本語 口頭発表(招待・特別) 公開
From Basic Research to Bio-Ventures (Startup): Japanese Perspective From Basic Research to Bio-Ventures (Startup): Japanese Perspective From Basic Research to Bio-Ventures (Startup): Japanese Perspective 第30回京都賞学生フォーラム 第30回京都賞学生フォーラム 2014/11/14 英語 口頭発表(招待・特別) 公開
糖鎖修飾DDSによる細胞特異的送達とがん治療 糖鎖修飾DDSによる細胞特異的送達とがん治療 文部科学省・次世代がん研究シーズ戦略的育成プログラムDDSシンポジウム 文部科学省・次世代がん研究シーズ戦略的育成プログラムDDSシンポジウム 2014/10/16 日本語 口頭発表(一般) 公開
ターゲティング型DDSの設計と評価 ターゲティング型DDSの設計と評価 第30回日本DDS学会学術集会 第30回日本DDS学会学術集会 2014/07/30 日本語 口頭発表(招待・特別) 公開
製剤開発の最新動向-DDS技術開発から薬事・薬局方まで- 製剤開発の最新動向-DDS技術開発から薬事・薬局方まで- 立命館大学製剤技術研究コンソーシアム2014年度第1回研究会 立命館大学製剤技術研究コンソーシアム2014年度第1回研究会 2014/06/06 日本語 口頭発表(招待・特別) 公開
Advances in Targeted and Gene Delivery Advances in Targeted and Gene Delivery Advances in Targeted and Gene Delivery The 4th International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity (BEW 2014) The 4th International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity (BEW 2014) The 4th International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity (BEW 2014) 2014/05/19 英語 口頭発表(招待・特別) 公開
Cell-specific Delivery of Nucleic Acid Drugs with a Combination of Glycosylated Bubble Lipoplexes and Ultrasound Exposure Cell-specific Delivery of Nucleic Acid Drugs with a Combination of Glycosylated Bubble Lipoplexes and Ultrasound Exposure Cell-specific Delivery of Nucleic Acid Drugs with a Combination of Glycosylated Bubble Lipoplexes and Ultrasound Exposure Emerging Trends in Gene/Cell-based Therapeutics and Nanocarriers for Drug Delivery Emerging Trends in Gene/Cell-based Therapeutics and Nanocarriers for Drug Delivery Emerging Trends in Gene/Cell-based Therapeutics and Nanocarriers for Drug Delivery 2014/04/25 英語 口頭発表(招待・特別) 公開
製剤開発の世界の潮流 製剤開発の世界の潮流 フロイント産業株式会社 創業50周年記念講演会「創業50周年 感謝と友に」 フロイント産業株式会社 創業50周年記念講演会「創業50周年 感謝と友に」 2014/04/22 日本語 口頭発表(招待・特別) 公開
Pharmaceutical Sciences 2020: Cutting Edge Technologies in Drug Delivery Pharmaceutical Sciences 2020: Cutting Edge Technologies in Drug Delivery Pharmaceutical Sciences 2020: Cutting Edge Technologies in Drug Delivery The 5th FIP Pharmaceutical Sciences World Congress The 5th FIP Pharmaceutical Sciences World Congress The 5th FIP Pharmaceutical Sciences World Congress 2014/04/13 英語 口頭発表(招待・特別) 公開
The Role of FIP and Its Relation with WHO in Globalization of Traditional Medicine The Role of FIP and Its Relation with WHO in Globalization of Traditional Medicine The Role of FIP and Its Relation with WHO in Globalization of Traditional Medicine 日本薬学会第133年会 日本薬学会第133年会 2013/03/27 英語 口頭発表(一般) 公開
DDS研究の歩みと共に DDS研究の歩みと共に 第6回次世代を担う若手医療薬科学シンポジウム 第6回次世代を担う若手医療薬科学シンポジウム 2012/11/23 日本語 口頭発表(基調) 公開
DDS製剤概論~薬物治療の最適化実現を図るDDS技術~ DDS製剤概論~薬物治療の最適化実現を図るDDS技術~ 薬事エキスパート研修会「ナノメディシン(ナノ医薬品)によるDDSの現状と展望」 薬事エキスパート研修会「ナノメディシン(ナノ医薬品)によるDDSの現状と展望」 2012/11/13 日本語 口頭発表(一般) 公開
Smart Drug Delivery System Smart Drug Delivery System Smart Drug Delivery System FIP Centennial Congress of Pharmacy and Pharmaceutical Sciences 2012 FIP Centennial Congress of Pharmacy and Pharmaceutical Sciences 2012 FIP Centennial Congress of Pharmacy and Pharmaceutical Sciences 2012 2012/10/03 英語 口頭発表(招待・特別) 公開
New Drug Delivery Systems New Drug Delivery Systems New Drug Delivery Systems The 3rd International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity The 3rd International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity The 3rd International Regulatory Workshop on A to Z on Bioequivalence, Bioanalysis, Dissolution and Biosimilarity 2012/06/04 英語 口頭発表(招待・特別) 公開
薬物治療とドラッグデリバリーシステム 薬物治療とドラッグデリバリーシステム 薬工連携セミナー 薬工連携セミナー 2012/06/01 日本語 口頭発表(一般) 公開
Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure CLS-iCeMS Joint Symposium: "Crossing Boundaries: Stem Cells, Materials, Mesoscopic Sciences, and Beyond" CLS-iCeMS Joint Symposium: "Crossing Boundaries: Stem Cells, Materials, Mesoscopic Sciences, and Beyond" CLS-iCeMS Joint Symposium: "Crossing Boundaries: Stem Cells, Materials, Mesoscopic Sciences, and Beyond" 2012/04/20 英語 口頭発表(招待・特別) 公開
Future prospect of DDS and imaging technology Future prospect of DDS and imaging technology Future prospect of DDS and imaging technology 薬物動態国際シンポジウム 薬物動態国際シンポジウム 2012/01/16 英語 口頭発表(一般) 公開
Nanotechnology for Health Nanotechnology for Health Nanotechnology for Health The Eighth Annual Meeting of the Science and Technology in Society (STS) forum The Eighth Annual Meeting of the Science and Technology in Society (STS) forum The Eighth Annual Meeting of the Science and Technology in Society (STS) forum 2011/10/02 英語 口頭発表(一般) 公開
New technologies impacting drug discovery New technologies impacting drug discovery New technologies impacting drug discovery World Congress of Pharmacy and Pharmaceutical Sciences 2011 World Congress of Pharmacy and Pharmaceutical Sciences 2011 World Congress of Pharmacy and Pharmaceutical Sciences 2011 2011/09/03 英語 口頭発表(一般) 公開
Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure Cell-specific delivery of nucleic acid drugs with a combination of glycosylated bubble lipoplexes and ultrasound exposure The 38th Annual Meeting and Exposition of the Controlled Release Society The 38th Annual Meeting and Exposition of the Controlled Release Society The 38th Annual Meeting and Exposition of the Controlled Release Society 2011/07/30 英語 口頭発表(招待・特別) 公開
薬学教育の在り方に関する日本学術会議の提言 薬学教育の在り方に関する日本学術会議の提言 日本薬剤学会第26年会 日本薬剤学会第26年会 2011/05/29 日本語 口頭発表(一般) 公開

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タイトル言語:
書籍等出版物
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 出版社 出版社(日本語) 出版社(英語) 出版年月 記述言語 担当区分 公開
橋田 充 橋田 充 HASHIDA Mitsuru Trends and Future Perspectives in Peptide and Protein Drug Delivery Trends and Future Perspectives in Peptide and Protein Drug Delivery Trends and Future Perspectives in Peptide and Protein Drug Delivery Harwood Academic Publishers Harwood Academic Publishers Harwood Academic Publishers 1995 共著 公開
橋田 充 橋田 充 HASHIDA Mitsuru Drug Delivery System-Challenge for Drug Development and Therapy Drug Delivery System-Challenge for Drug Development and Therapy Drug Delivery System-Challenge for Drug Development and Therapy 1995 公開
橋田 充 橋田 充 ドラッグデリバリーシステム-創薬と治療への新たなる挑戦 ドラッグデリバリーシステム-創薬と治療への新たなる挑戦 化学同人 化学同人 1995 公開
橋田 充 橋田 充 生体内薬物送達学 生体内薬物送達学 産業図書 産業図書 1994 共著 公開
橋田 充 橋田 充 バイオコンジュゲート医薬品 バイオコンジュゲート医薬品 廣川書店 廣川書店 1993 公開
橋田 充 橋田 充 生体適合材料〈その機能と応用〉 生体適合材料〈その機能と応用〉 日本規格協会 日本規格協会 1993 公開
橋田 充 橋田 充 HASHIDA Mitsuru Chemical Modification and Disposition of Proteins and Peptides: Biopharmaceutical Aspects. in "Topics in Pharmaceutical Sciences 1991" Chemical Modification and Disposition of Proteins and Peptides: Biopharmaceutical Aspects. in "Topics in Pharmaceutical Sciences 1991" Chemical Modification and Disposition of Proteins and Peptides: Biopharmaceutical Aspects. in "Topics in Pharmaceutical Sciences 1991" SDU Publishers SDU Publishers SDU Publishers 1992 公開
橋田 充 橋田 充 HASHIDA Mitsuru Lymphatic Transport after Parenteral Drug Administration. in "Lymphatic Transport of Drugs" Lymphatic Transport after Parenteral Drug Administration. in "Lymphatic Transport of Drugs" Lymphatic Transport after Parenteral Drug Administration. in "Lymphatic Transport of Drugs" CRC Press CRC Press CRC Press 1991 公開
タイトル言語:
学術賞等
賞の名称(日本語) 賞の名称(英語) 授与組織名(日本語) 授与組織名(英語) 年月
タケル・アヤ・ヒグチ記念賞 1990
FIP Pharmaceutical Scientist of the Year Award 1998 国際薬学連合 International Pharmaceutical Federation (FIP) 1998
日本薬剤学会賞 日本薬剤学会 Academy of Pharmaceutical Science and Technology, Japan (APSTJ) 1999
日本薬学会賞 日本薬学会 Pharmaceutical Society of Japan (PSJ) 2005
Founders Award コントロールドリリース学会 Controlled Release Society (CRS) 2005
Research Achievement Award in Pharmaceutics and Drug Delivery アメリカ薬学会 American Association of Pharmaceutical Scientists (AAPS) 2007
日本薬物動態学会賞 日本薬物動態学会 Japanese Society for the Study of Xenobiotics (JSSX) 2010
FIP Fellow Award 国際薬学連合 International Pharmaceutical Federation (FIP) 2010
フェロー称号 日本薬物動態学会 The Japanese Society for the Study of Xenobiotics (JSSX) 2011
Lifetime Achievement Award Journal of Drug Targeting 2012
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
特定領域研究 代表 がん増殖・転移におけるバイオイメージングとターゲティング型DDS開発 2005/04/01〜2010/03/31
基盤研究(A) 代表 体内および細胞内リアルタイム動態解析に基づく遺伝子キャリアデザインの最適化  2006/04/01〜2009/03/31
萌芽研究 代表 免疫細胞指向性ナノ粒子によるNFkB転写制御と移植拒絶抑制への応用 2007/04/01〜2009/03/31
挑戦的萌芽研究 代表 トランスポゾンを用いたin vivo遺伝子発現長期化による新規慢性疾患療法の開発 2009/04/01〜2011/03/31
基盤研究(A) 代表 がん細胞の環境防御機構を標的としたドラッグデリバリーシステム治療戦略 2011/04/01〜2014/03/31
特別研究員奨励費 代表 リポソーム技術を応用した新規細胞特異的遺伝子送達法の開発 2011/04/01〜2013/03/31
新学術領域研究 代表 腫瘍関連マクロファージへの核酸DDSの開発 2011/04/01〜2013/03/31
挑戦的萌芽研究 代表 トランスポゾンによる長期遺伝子発現型初代培養細胞の創製と細胞治療への応用 2011/04/01〜2013/03/31
挑戦的萌芽研究 代表 幹細胞を用いた炎症部位特異的な新規遺伝子発現システムの開発とDDSへの応用 2013/04/01〜2015/03/31
挑戦的萌芽研究 代表 非天然アミノ酸を利用した新規細胞膜表面修飾法の開発とDDSへの応用 (平成27年度分) 2015/04/01〜2016/03/31
外部資金:競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
細胞特異的薬物送達に関する研究 Study on Cell Specific Drug Delivery
遺伝子治療における製剤設計に関する研究 Study on Dosage Form Design for Gene Therapy
経皮治療システムの開発に関する研究 Study on Development of Therapeutic Transdermal System
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
医療薬学I(薬剤学) 後期 薬学部 2011/04〜2012/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and 前期不定 薬学研究科 2011/04〜2012/03
基盤医療薬科学実験技術(秋入学用) Basic Laboratory Techniques in Pharmacy and 後期不定 薬学研究科 2011/04〜2012/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2011/04〜2012/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and 通年不定 薬学研究科 2011/04〜2012/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2011/04〜2012/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2011/04〜2012/03
臨床薬学総論 後期 薬学部 2011/04〜2012/03
薬剤学2(固形製剤論) 前期 薬学部 2011/04〜2012/03
薬剤学1(溶液製剤論) 後期 薬学部 2011/04〜2012/03
薬局方・薬事関連法規 前期 薬学部 2011/04〜2012/03
先端薬学論 Frontier in pharmaceutical science 後期不定 薬学研究科 2012/04〜2013/03
医療薬学IV(医薬品安全性学) Medicinal Pharmacy IV(Drug Safety) 前期 薬学部 2012/04〜2013/03
医療薬学I(薬剤学) Medicinal Pharmacy I(Pharmaceutics) 後期 薬学部 2012/04〜2013/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2012/04〜2013/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2012/04〜2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2012/04〜2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2012/04〜2013/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2012/04〜2013/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2012/04〜2013/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2012/04〜2013/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2012/04〜2013/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2012/04〜2013/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2012/04〜2013/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2012/04〜2013/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2012/04〜2013/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2012/04〜2013/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2012/04〜2013/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2012/04〜2013/03
薬剤学2(固形製剤論) Pharmaceutics 2 (Solid formulations) 前期 薬学部 2012/04〜2013/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2012/04〜2013/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2012/04〜2013/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2012/04〜2013/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2012/04〜2013/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2012/04〜2013/03
医療薬学IV(医薬品安全性学) Medicinal Pharmacy IV(Drug Safety) 前期 薬学部 2013/04〜2014/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2013/04〜2014/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2013/04〜2014/03
薬剤学2(固形製剤論) Pharmaceutics 2 (Solid formulations) 前期 薬学部 2013/04〜2014/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2013/04〜2014/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2013/04〜2014/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2013/04〜2014/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2013/04〜2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2013/04〜2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2013/04〜2014/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2013/04〜2014/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2013/04〜2014/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2013/04〜2014/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2013/04〜2014/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2013/04〜2014/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2013/04〜2014/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2013/04〜2014/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2013/04〜2014/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2013/04〜2014/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2013/04〜2014/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2013/04〜2014/03
先端薬学論 Frontier in pharmaceutical science 後期不定 薬学研究科 2013/04〜2014/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2013/04〜2014/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2013/04〜2014/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2014/04〜2015/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2014/04〜2015/03
薬剤学2(固形製剤論) Pharmaceutics 2 (Solid formulations) 前期 薬学部 2014/04〜2015/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2014/04〜2015/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2014/04〜2015/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2014/04〜2015/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2014/04〜2015/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2014/04〜2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2014/04〜2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2014/04〜2015/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2014/04〜2015/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2014/04〜2015/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2014/04〜2015/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2014/04〜2015/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2014/04〜2015/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2014/04〜2015/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2014/04〜2015/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2014/04〜2015/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2014/04〜2015/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2014/04〜2015/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2014/04〜2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2015/04〜2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2015/04〜2016/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2015/04〜2016/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2015/04〜2016/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2015/04〜2016/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2015/04〜2016/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2015/04〜2016/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2015/04〜2016/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2015/04〜2016/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2015/04〜2016/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2015/04〜2016/03
薬剤学2(固形製剤論) Pharmaceutics 2 (Solid formulations) 前期 薬学部 2015/04〜2016/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2015/04〜2016/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2015/04〜2016/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2015/04〜2016/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2015/04〜2016/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2015/04〜2016/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2015/04〜2016/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2015/04〜2016/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2015/04〜2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2016/04〜2017/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2016/04〜2017/03
基盤医療薬科学概論 Introduction to Basic Pharmacy and Biomedical Sciences 前期不定 薬学研究科 2016/04〜2017/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2016/04〜2017/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2016/04〜2017/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2016/04〜2017/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2016/04〜2017/03
統合科学 Interdisciplinary Sciences 後期 全学共通科目 2016/04〜2017/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2016/04〜2017/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2016/04〜2017/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2016/04〜2017/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2016/04〜2017/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2016/04〜2017/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2016/04〜2017/03
薬剤学2(固形製剤論) Pharmaceutics 2 (Solid formulations) 前期 薬学部 2016/04〜2017/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2016/04〜2017/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2016/04〜2017/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2016/04〜2017/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2016/04〜2017/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2016/04〜2017/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2016/04〜2017/03
薬物動態学(LIMS) Biopharmaceutics 後期集中 医学研究科 2016/04〜2017/03

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全学運営(役職等)
役職名 期間
英文一覧等小委員会 委員 2008/04/01〜2010/10/14
国際交流委員会 委員 2008/04/01〜2010/03/31
教育制度委員会 委員 2010/04/01〜2011/03/31
総長選考会議委員 2004/05/01〜
教育制度委員会 委員 2010/04/01〜2014/03/31
教育制度委員会 委員 2012/04/01〜2014/03/31
国際交流委員会 委員 2013/04/01〜2013/06/30
国際交流委員会 委員 2013/07/01〜2015/06/30
教育制度委員会 委員 2014/04/01〜2016/03/31
教育制度委員会:研究科横断型教育企画実施委員会 委員 2011/04/01〜2012/03/31
教育制度委員会WG2 委員 2012/04/01〜2013/03/31
国際交流委員会 委員 2013/04/01〜2015/06/30
教育制度委員会WG2 委員 2013/04/01〜2014/03/31
教育制度委員会:教務情報システム検討WG 委員 2014/04/01〜2015/03/31
教育制度委員会WG2 委員 2014/04/01〜2015/03/31

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部局運営(役職等)
役職名 期間
寄附講座「医薬産業政策学講座」運営委員長 2011/04/01〜
統合薬学教育開発センター運営委員会 委員 2011/04/01〜
革新的ナノバイオ創薬研究拠点 運営委員会 委員 2011/04/01〜2014/03/31
実務実習委員会 委員 2011/04/01〜2013/03/31
国際交流委員会 委員長 2013/04/01〜
寄附講座「ナノバイオ医薬創成科学講座」運営委員 2013/04/01〜
入試等問題検討委員会 委員 2014/04/01〜2015/03/31
学会活動:学会役員歴
学会名(日本語) 学会名(英語) 役職名(日本語) 役職名(英語) 期間
日本薬剤学会 Academy of Pharmaceutical Sciences and Technology, Japan (APSTJ) 評議員 1990〜
日本薬物動態学会 Japanese Society for the Study of Xenobiotics (JSSX) 評議員 1990〜
国際薬学連合 International Pharmaceutical Federation (FIP) 副会長 Vice-president 2000〜2008
コントロールドリリース学会 Controlled Release Society (CRS) 常任理事 Member-at-Large 2001〜2003
日本DDS学会 Japan Society of Drug Delivery System (JSDDS) 理事長 President 2003〜2009
日本薬剤学会 Academy of Pharmaceutical Sciences and Technology, Japan (APSTJ) 会長 President 2006〜2008
国際薬学連合学術部門 Board of Pharmaceutical Sciences, International Pharmaceutical Federation (FIP) 議長 Chairman 2008〜2012
日本癌学会 Japanese Cancer Association (JCA) 評議員 2008〜2013
日本薬学会 Pharmaceutical Society of Japan (PSJ) 副会頭 Vice-president 2009〜2010
日本医療薬学会 Japanese Society of Pharmaceutical Health Care and Sciences (JSPHCS) 代議員 2009〜2013
日本DDS学会 Japan Society of Drug Delivery System (JSDDS) 顧問 2009〜2018
日本DDS学会 Japan Society of Drug Delivery System (JSDDS) 評議員 2009〜2018
日本レギュラトリーサイエンス学会 Society for Regulatory Science of Medical Products 理事 2010〜2014
日本化学会 Chemical Society of Japan (CSJ) 化学便覧応用化学編編集委員会委員 2011〜2014
国際薬学連合学術部門 Board of Pharmaceutical Sciences, International Pharmaceutical Federation (FIP) 前議長 Immediate Past Chairman 2012〜

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その他活動:国・地方公共団体での活動
委員会名(日本語) 委員会名(英語) 役職名 公共団体の名称 期間
薬学系人材育成の在り方に関する検討会 委員 文部科学省 2006/04/01〜2015/03/31
専門委員 医薬品医療機器総合機構 2006/04/01〜2016/03/31
東京高等裁判所・東京地方裁判所・大阪地方裁判所所属専門委員(知的財産関係) 知的財産高等裁判所 2009/04/01〜2017/03/31
NEDO技術委員 新エネルギー・産業技術総合開発機構 2010/01/18〜2015/03/31
薬事・食品衛生審議会 委員 厚生労働省 2010/12/06〜2017/01/24
革新的医薬品・医療機器・再生医療製品実用化促進事業評価検討会 構成員 厚生労働省 2012/03/13〜2016/03/31
薬事・食品衛生審議会 会長 厚生労働省 2015/01/26〜2017/01/24
国際的機関での活動
活動内容(日本語) 活動内容(英語) 活動機関名 期間
副会長 Vice-president International Pharmaceutical Federation (FIP) 2000〜2008
常務理事 Member-at-large Controlled Release Society (CRS) 2001〜2003
国際薬学連合学術部門議長 Chairman, Board of Pharmaceutical Sciences International Pharmaceutical Federation (FIP) 2008〜2012
外国人滞在者受入れ
滞在者名 所属機関名 部署 研究テーマ 国名 期間
Johan Mikael Unga Drug Delivery System スウェーデン 2012/04/01〜2014/03/31