山門 穂高

最終更新日時: 2020/09/18 14:17:07

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氏名(漢字/フリガナ/アルファベット表記)
山門 穂高/ヤマカド ホダカ/Yamakado, Hodaka
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/脳神経内科/特定准教授
連絡先住所
種別 住所(日本語) 住所(英語)
職場 京都市左京区聖護院川原町54 京都大学医学部付属病院神経内科
連絡先電話番号
種別 番号
職場 075-751-3767
所属学会(国内)
学会名(日本語) 学会名(英語)
日本神経学会 Japanese society of neurology
日本内科学会 Japanese Society of Internal Medicine
所属学会(海外)
学会名(英語) 国名
Society For Neuroscience 米国
International Parkinson and Movement Disorder Society
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
京都大学 大学院医学研究科博士課程脳統御医科学専攻 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
京都大学 医学部医学科 卒業
出身高等学校
高等学校名 ふりがな
三重高田高等学校 みえたかだこうとうがっこう
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
2000/4〜2003/3 虎の門病院 内科 Department of Internal Medicine, Toranomon Hospital 研修医 Resident
2003/4〜2005/3 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 医員 Clinical fellow
2009/4〜2010/9 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 助教 Assistant professor
2010/10/〜2011/3 武田総合病院 神経内科 Department of Neurology, Takeda General Hospital 医長 Clinical fellow
2011/4〜2019/03/31 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 助教 Assistant professor
2019/04/01〜 京都大学医学部附属病院 脳神経内科 Department of Neurology Kyoto University Hospital 特定准教授 Research Associate Professor
プロフィール
(日本語)
研究においては、様々なモデル動物を用いたパーキンソン病・多系統委縮症の病態解析・治療法開発、臨床においては京都大学病院においてパーキンソン病を中心とした神経内科の一般診療を行っている。
(英語)
My research interest is focused on the pathomechanism of Parkinson's disease (PD) / multiple system atrophy (MSA) and development of novel therapeutics for PD/MSA. Also, I am working as a general neurologist at Kyoto University Hospital . 
使用言語
言語名(japanese) 言語名(english) コード
英語 English eng
researchmap URL
https://researchmap.jp/7000008893
研究テーマ
(日本語)
神経変性疾患の分子生物学的研究
(英語)
Molecular biology of neurodegenerative disorders
研究概要
(日本語)
神経変性疾患、特にパーキンソン病(Parkinson's disease, PD)や多系統萎縮症において、様々なモデル動物(マウス、ラット、メダカ)やiPS細胞を用いてモデル動物の開発、病態メカニズムの解明、新規治療法の開発を目指した研究を行っている。特にα-synucleinやglucocerebrosidase (GBA)といった孤発性PDに深く関与する分子を中心とした研究を行っている。
(英語)
My research is fosused on the development of model for Parkinson's disease and multiple system atrophy using mice, rat, medaka fish and patients-derived iPS cells as well as investigation of pathomechanisms underlying PD and development of novel therapeutics for PD.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
神経内科学 Neurology
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy. BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy. BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy. Acta neuropathologica communications, 8, 1, 120-120 Acta neuropathologica communications, 8, 1, 120-120 Acta neuropathologica communications, 8, 1, 120-120 2020/07/29 英語 研究論文(学術雑誌) 公開
Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line. Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line. Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line. FEBS open bio FEBS open bio FEBS open bio 2020/07/01 英語 研究論文(学術雑誌) 公開
Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease. Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease. Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease. Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429 Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429 Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429 2020/04 英語 研究論文(学術雑誌) 公開
Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi Animal Model for Prodromal Parkinson's Disease. Animal Model for Prodromal Parkinson's Disease. Animal Model for Prodromal Parkinson's Disease. International journal of molecular sciences, 21, 6 International journal of molecular sciences, 21, 6 International journal of molecular sciences, 21, 6 2020/03/13 英語 研究論文(学術雑誌) 公開
Uemura N, Yagi H, Uemura MT, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Yamakado H, Takahashi R Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract. Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract. Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract. Neuroscience letters, 716, 134651-134651 Neuroscience letters, 716, 134651-134651 Neuroscience letters, 716, 134651-134651 2020/01/18 英語 研究論文(学術雑誌) 公開
Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody. Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody. Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody. Muscle & nerve, 61, 1, 81-87 Muscle & nerve, 61, 1, 81-87 Muscle & nerve, 61, 1, 81-87 2020/01 英語 研究論文(学術雑誌) 公開
Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions. Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions. Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions. Translational neurodegeneration, 9, 7-7 Translational neurodegeneration, 9, 7-7 Translational neurodegeneration, 9, 7-7 2020 英語 研究論文(学術雑誌) 公開
Taguchi T, Ikuno M, Hondo M, Parajuli LK, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf OMA, Koike M, Yanagisawa M, Uemura MT, Yamakado H, Takahashi R Taguchi T, Ikuno M, Hondo M, Parajuli LK, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf OMA, Koike M, Yanagisawa M, Uemura MT, Yamakado H, Takahashi R Tomoyuki Taguchi, Masashi Ikuno, Mari Hondo, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Jun Ueda, Masanori Sawamura, Shinya Okuda, Etsuro Nakanishi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Takashi Ayaki, Shuichi Matsuzawa, Masaki Tanaka, Omar M A El-Agnaf, Masato Koike, Masashi Yanagisawa, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi α-Synuclein BAC transgenic mice exhibited RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model. α-Synuclein BAC transgenic mice exhibited RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model. α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model. Brain, 143, 1, 249-265 Brain, 143, 1, 249-265 Brain : a journal of neurology, 143, 1, 249-265 2020/01/01 英語 研究論文(学術雑誌) 公開
Ishimoto T, Yamakado H Ishimoto T, Yamakado H Ishimoto T, Yamakado H TPPP/p25α Is an old and new therapeutic target in multiple system atrophy. TPPP/p25α Is an old and new therapeutic target in multiple system atrophy. TPPP/p25α Is an old and new therapeutic target in multiple system atrophy. Movement disorders Movement disorders Movement disorders 2019/11 公開
Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Yusuke Hatanaka, Hodaka Yamakado, Ryosuke Takahashi Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Mol Neurodegener, 14, 1, 31-31 Mol Neurodegener, 14, 1, 31-31 Molecular neurodegeneration, 14, 1, 31-31 2019/07/26 英語 研究論文(学術雑誌) 公開
Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease. GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease. GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease. Human molecular genetics, 28, 11, 1894-1904 Human molecular genetics, 28, 11, 1894-1904 Human molecular genetics, 28, 11, 1894-1904 2019/06/01 英語 研究論文(学術雑誌) 公開
Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Neurology. Genetics, 4, 6, e283 Neurology. Genetics, 4, 6, e283 Neurology. Genetics, 4, 6, e283 2018/12 公開
Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN) Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN) Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN) American Journal of Case Reports, 19, 1249-1252 American Journal of Case Reports, 19, 1249-1252 American Journal of Case Reports, 19, 1249-1252 2018/10/20 研究論文(学術雑誌) 公開
Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Molecular neurodegeneration, 13, 1, 43 Molecular neurodegeneration, 13, 1, 43 Molecular neurodegeneration, 13, 1, 43 2018/08 公開
Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. eNeuro, 5, 4 eNeuro, 5, 4 eNeuro, 5, 4 2018/07 公開
Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Molecular neurodegeneration, 13, 1, 21 Molecular neurodegeneration, 13, 1, 21 Molecular neurodegeneration, 13, 1, 21 2018/05 公開
Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Internal medicine, 57, 13, 1917-1919 Internal medicine, 57, 13, 1917-1919 Internal medicine, 57, 13, 1917-1919 2018/02 公開
Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity NEUROSCIENCE RESEARCH, 124, 25-32 NEUROSCIENCE RESEARCH, 124, 25-32 NEUROSCIENCE RESEARCH, 124, 25-32 2017/11 英語 研究論文(学術雑誌) 公開
Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837 JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837 JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837 2017/09 英語 研究論文(学術雑誌) 公開
Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures SCIENTIFIC REPORTS, 7, 1, 8019 SCIENTIFIC REPORTS, 7, 1, 8019 SCIENTIFIC REPORTS, 7, 1, 8019 2017/08 英語 研究論文(学術雑誌) 公開
Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type SCIENTIFIC REPORTS, 7, 1, 9008 SCIENTIFIC REPORTS, 7, 1, 9008 SCIENTIFIC REPORTS, 7, 1, 9008 2017/08 英語 研究論文(学術雑誌) 公開
Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases JOURNAL OF NEUROLOGY, 263, 9, 1719-1726 JOURNAL OF NEUROLOGY, 263, 9, 1719-1726 JOURNAL OF NEUROLOGY, 263, 9, 1719-1726 2016/09 英語 研究論文(学術雑誌) 公開
Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome Clinical Neurology, 56, 6, 424-429 Clinical Neurology, 56, 6, 424-429 Clinical Neurology, 56, 6, 424-429 2016 日本語 研究論文(学術雑誌) 公開
Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein PLOS GENETICS, 11, 4, e1005065 PLOS GENETICS, 11, 4, e1005065 PLOS GENETICS, 11, 4, e1005065 2015/04 英語 研究論文(学術雑誌) 公開
Hodaka Yamakado Hodaka Yamakado Hodaka Yamakado Advance in PD Research Explored a New Field on Ubiquitin Biology Advance in PD Research Explored a New Field on Ubiquitin Biology Advance in PD Research Explored a New Field on Ubiquitin Biology MOVEMENT DISORDERS, 29, 10, 1243-1243 MOVEMENT DISORDERS, 29, 10, 1243-1243 MOVEMENT DISORDERS, 29, 10, 1243-1243 2014/09 英語 公開
Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310 JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310 JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310 2014 英語 公開
Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody Clinical Neurology, 54, 7, 543-549 Clinical Neurology, 54, 7, 543-549 Clinical Neurology, 54, 7, 543-549 2014 英語 研究論文(学術雑誌) 公開
Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction NEUROSCIENCE RESEARCH, 77, 4, 228-233 NEUROSCIENCE RESEARCH, 77, 4, 228-233 NEUROSCIENCE RESEARCH, 77, 4, 228-233 2013/12 英語 研究論文(学術雑誌) 公開
Ryosuke Takahashi, Hodaka Yamakado Ryosuke Takahashi, Hodaka Yamakado Ryosuke Takahashi, Hodaka Yamakado Genetic correction will be a standard method for the patient-derived ips cell research? Genetic correction will be a standard method for the patient-derived ips cell research? Genetic correction will be a standard method for the patient-derived ips cell research? Movement Disorders, 28, 14, 1935-1935 Movement Disorders, 28, 14, 1935-1935 Movement Disorders, 28, 14, 1935-1935 2013/12 英語 研究論文(学術雑誌) 公開
Hodaka Yamakado, Ryosuke Takahashi Hodaka Yamakado, Ryosuke Takahashi Hodaka Yamakado, Ryosuke Takahashi The Function of Parkin: Revisited The Function of Parkin: Revisited The Function of Parkin: Revisited MOVEMENT DISORDERS, 28, 14, 1936-1936 MOVEMENT DISORDERS, 28, 14, 1936-1936 MOVEMENT DISORDERS, 28, 14, 1936-1936 2013/12 英語 公開
Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice MOLECULAR BRAIN, 6, 35 MOLECULAR BRAIN, 6, 35 MOLECULAR BRAIN, 6, 35 2013/08 英語 研究論文(学術雑誌) 公開
Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434 HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434 HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434 2013/06 英語 研究論文(学術雑誌) 公開
Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O Silke Nuber, Florian Harmuth, Zacharias Kohl, Anthony Adame, Margaritha Trejo, Kai Schönig, Frank Zimmermann, Claudia Bauer, Nicolas Casadei, Christiane Giel, Carsten Calaminus, Bernd J. Pichler, Poul H. Jensen, Christian P. Müller, Davide Amato, Johannes Kornhuber, Peter Teismann, Hodaka Yamakado, Ryosuke Takahashi, Juergen Winkler, Eliezer Masliah, Olaf Riess A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats Brain, 136, 2, 412-432 Brain, 136, 2, 412-432 Brain, 136, 2, 412-432 2013 英語 研究論文(学術雑誌) 公開
Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Junko Kurisu, Kengo Uemura, Haruhisa Inoue, Makio Takahashi, Ryosuke Takahashi α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. alpha-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion Neuroscience research, 73, 2, 173-177 Neuroscience research, 73, 2, 173-177 NEUROSCIENCE RESEARCH, 73, 2, 173-177 2012/06 英語 研究論文(学術雑誌) 公開
Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report Clinical Neurology, 49, 1, 43-47 Clinical Neurology, 49, 1, 43-47 Clinical Neurology, 49, 1, 43-47 2009 日本語 研究論文(学術雑誌) 公開
H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama Cocaine and phenylephrine eye drop test for Parkinson disease Cocaine and phenylephrine eye drop test for Parkinson disease Cocaine and phenylephrine eye drop test for Parkinson disease JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934 2005/02 英語 公開

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タイトル言語:
Misc
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝 之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔 引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝 之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔 引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝 之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔 FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像:若年発症例を含む4症例の検討 FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像:若年発症例を含む4症例の検討 FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像:若年発症例を含む4症例の検討 56th Annual Meeting of the Japanese Society of Neurology, Niigata. 56th Annual Meeting of the Japanese Society of Neurology, Niigata. 56th Annual Meeting of the Japanese Society of Neurology, Niigata. 2015/05/21 公開
Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi iPS cell modeling of genetic Parkinson's disease iPS cell modeling of genetic Parkinson's disease iPS cell modeling of genetic Parkinson's disease MOVEMENT DISORDERS, 29, S68-S68 MOVEMENT DISORDERS, 29, S68-S68 MOVEMENT DISORDERS, 29, S68-S68 2014/11 英語 研究発表要旨(国際会議) 公開
N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain MOVEMENT DISORDERS, 28, S373-S374 MOVEMENT DISORDERS, 28, S373-S374 MOVEMENT DISORDERS, 28, S373-S374 2013/06 英語 研究発表要旨(国際会議) 公開
H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior MOVEMENT DISORDERS, 27, S498-S498 MOVEMENT DISORDERS, 27, S498-S498 MOVEMENT DISORDERS, 27, S498-S498 2012/06 英語 研究発表要旨(国際会議) 公開
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi Pael-R, a substrate of Parkin, can also be cleared by PINK1 Pael-R, a substrate of Parkin, can also be cleared by PINK1 Pael-R, a substrate of Parkin, can also be cleared by PINK1 NEUROSCIENCE RESEARCH, 71, E192-E192 NEUROSCIENCE RESEARCH, 71, E192-E192 NEUROSCIENCE RESEARCH, 71, E192-E192 2011 英語 研究発表要旨(国際会議) 公開
Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease NEUROSCIENCE RESEARCH, 71, E189-E189 NEUROSCIENCE RESEARCH, 71, E189-E189 NEUROSCIENCE RESEARCH, 71, E189-E189 2011 英語 研究発表要旨(国際会議) 公開
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi PaelR, a substrate of Parkin, can also be decreased by PINK1 PaelR, a substrate of Parkin, can also be decreased by PINK1 PaelR, a substrate of Parkin, can also be decreased by PINK1 NEUROSCIENCE RESEARCH, 68, E258-E258 NEUROSCIENCE RESEARCH, 68, E258-E258 NEUROSCIENCE RESEARCH, 68, E258-E258 2010 英語 研究発表要旨(国際会議) 公開
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures NEUROSCIENCE RESEARCH, 65, S118-S118 NEUROSCIENCE RESEARCH, 65, S118-S118 NEUROSCIENCE RESEARCH, 65, S118-S118 2009 英語 研究発表要旨(国際会議) 公開
Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi PARK4 mouse model PARK4 mouse model PARK4 mouse model NEUROSCIENCE RESEARCH, 61, S265-S265 NEUROSCIENCE RESEARCH, 61, S265-S265 NEUROSCIENCE RESEARCH, 61, S265-S265 2008 英語 研究発表要旨(国際会議) 公開
タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 開催年月日 記述言語 会議種別 公開
Animal model for disease-modifying therapies in Parkinson's disease Animal model for disease-modifying therapies in Parkinson's disease Animal model for disease-modifying therapies in Parkinson's disease 第61回 日本神経学会学術大会 (シンポジウム) 第61回 日本神経学会学術大会 (シンポジウム) 2020/09/01 英語 シンポジウム・ワークショップパネル(指名) 公開
パーキンソン病の前駆期症状を呈するマウスモデルの開発 パーキンソン病の前駆期症状を呈するマウスモデルの開発 日本自律神経学会 日本自律神経学会 2019/11/02 公開
Prodromal PD mice model Prodromal PD mice model Neuro2019 (Symposium) Neuro2019 (Symposium) 2019/07/27 英語 シンポジウム・ワークショップパネル(公募) 公開
α-シヌクレイン凝集抑制治療は、 疾患修飾治療になりうるか? α-シヌクレイン凝集抑制治療は、 疾患修飾治療になりうるか? MDSJ 2019 (Controversy) MDSJ 2019 (Controversy) 2019/07/26 公開
Prodromal PDの動物モデル Prodromal PDの動物モデル MDSJ (Symposium) MDSJ (Symposium) 2018/07/06 公開
タイトル言語:
外部資金:競争的資金 (科学研究費補助金)
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
若手研究(B) 代表 新しいシヌクレイン遺伝子導入マウスを用いたパーキンソン病発症メカニズムの解明 Investigation of pathomechanism of Parkinson's disease using novel alpha-synuclein-based genetic mice model 2012〜2014
若手研究(B) 代表 iPS細胞を用いた孤発性パーキンソン病の病態解明と標的分子の同定 Investigation of pathomechanism and identification of therapeutic target of Parkinson's disease using iPS cells 2014〜2016
基盤研究(C) 代表 多系統萎縮症の病態解明と治療法の開発 2016〜2019
基盤B 代表 パーキンソン病関連疾患のモデル作製と治療薬開発 2020/04/01〜2023/03/31
部局運営(役職等)
役職名 期間
動物実験施設運営委員会 2013/04/01〜2014/03/31
外来医長・看護師長会議 委員 2014/04/01〜