山門 穂高

最終更新日時: 2019/04/04 16:35:07

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氏名(漢字/フリガナ/アルファベット表記)
山門 穂高/ヤマカド ホダカ/Hodaka Yamakado
所属部署・職名(部局/所属/講座等/職名)
医学部附属病院/内科(脳神経内科)/特定准教授
連絡先住所
種別 住所(日本語) 住所(英語)
職場 京都市左京区聖護院川原町54 京都大学医学部付属病院神経内科
連絡先電話番号
種別 番号
職場 075-751-3767
所属学会(国内)
学会名(日本語) 学会名(英語)
日本神経学会 Japanese society of neurology
日本内科学会 Japanese Society of Internal Medicine
所属学会(海外)
学会名(英語) 国名
Society For Neuroscience 米国
International Parkinson and Movement Disorder Society
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
京都大学 大学院医学研究科博士課程脳統御医科学専攻 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
京都大学 医学部医学科 卒業
出身高等学校
高等学校名 ふりがな
三重高田高等学校 みえたかだこうとうがっこう
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
2000/4〜2003/3 虎の門病院 内科 Department of Internal Medicine, Toranomon Hospital 研修医 Resident
2003/4〜2005/3 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 医員 Clinical fellow
2009/4〜2010/9 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 助教 Assistant professor
2010/10/〜2011/3 武田総合病院 神経内科 Department of Neurology, Takeda General Hospital 医長 Clinical fellow
2011/4〜 京都大学医学部付属病院 神経内科 Department of Neurology, Kyoto University Hospital 助教 Assistant professor
プロフィール
(日本語)
研究においては、様々なモデル動物を用いたパーキンソン病・多系統委縮症の病態解析・治療法開発、臨床においては京都大学病院においてパーキンソン病を中心とした神経内科の一般診療を行っている。
(英語)
My research interest is focused on the pathomechanism of Parkinson's disease (PD) / multiple system atrophy (MSA) and development of novel therapeutics for PD/MSA. Also, I am working as a general neurologist at Kyoto University Hospital . 
研究テーマ
(日本語)
神経変性疾患の分子生物学的研究
(英語)
Molecular biology of neurodegenerative disorders
研究概要
(日本語)
神経変性疾患、特にパーキンソン病(Parkinson's disease, PD)や多系統萎縮症において、様々なモデル動物(マウス、ラット、メダカ)やiPS細胞を用いてモデル動物の開発、病態メカニズムの解明、新規治療法の開発を目指した研究を行っている。特にα-synucleinやglucocerebrosidase (GBA)といった孤発性PDに深く関与する分子を中心とした研究を行っている。
(英語)
My research is fosused on the development of model for Parkinson's disease and multiple system atrophy using mice, rat, medaka fish and patients-derived iPS cells as well as investigation of pathomechanisms underlying PD and development of novel therapeutics for PD.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
神経内科学 Neurology
研究分野(科研費分類コード)
科研費分類コード
神経内科学
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Ikuno M, Yamakado H, Akiyama H, Parajuli LK, Taguchi K, Hara J, Uemura N, Hatanaka Y, Higaki K, Ohno K, Tanaka M, Koike M, Hirabayashi Y, Takahashi R Ikuno M, Yamakado H, Akiyama H, Parajuli LK, Taguchi K, Hara J, Uemura N, Hatanaka Y, Higaki K, Ohno K, Tanaka M, Koike M, Hirabayashi Y, Takahashi R Ikuno M, Yamakado H, Akiyama H, Parajuli LK, Taguchi K, Hara J, Uemura N, Hatanaka Y, Higaki K, Ohno K, Tanaka M, Koike M, Hirabayashi Y, Takahashi R GBA haploinsufficiency accelerates alpha synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease=. GBA haploinsufficiency accelerates alpha synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease=. GBA haploinsufficiency accelerates alpha synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease=. Human molecular genetics Human molecular genetics Human molecular genetics 2019/01 公開
Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia. Neurology. Genetics, 4, 6, e283 Neurology. Genetics, 4, 6, e283 Neurology. Genetics, 4, 6, e283 2018/12 公開
Sakamoto A, Arai R, Okamoto T, Yamada Y, Yamakado H, Matsuda S Sakamoto A, Arai R, Okamoto T, Yamada Y, Yamakado H, Matsuda S Sakamoto A, Arai R, Okamoto T, Yamada Y, Yamakado H, Matsuda S Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN). Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN). Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN). The American journal of case reports, 19, 1249-1252 The American journal of case reports, 19, 1249-1252 The American journal of case reports, 19, 1249-1252 2018/10 公開
Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation. Molecular neurodegeneration, 13, 1, 43 Molecular neurodegeneration, 13, 1, 43 Molecular neurodegeneration, 13, 1, 43 2018/08 公開
Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. eNeuro, 5, 4 eNeuro, 5, 4 eNeuro, 5, 4 2018/07 公開
Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve. Molecular neurodegeneration, 13, 1, 21 Molecular neurodegeneration, 13, 1, 21 Molecular neurodegeneration, 13, 1, 21 2018/05 公開
Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. Internal medicine (Tokyo, Japan), 57, 13, 1917-1919 Internal medicine (Tokyo, Japan), 57, 13, 1917-1919 Internal medicine (Tokyo, Japan), 57, 13, 1917-1919 2018/02 公開
Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E Ihse E, Yamakado H, van Wijk XM, Lawrence R, Esko JD, Masliah E Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. Scientific reports, 7, 1, 9008 Scientific reports, 7, 1, 9008 Scientific reports, 7, 1, 9008 2017/08 公開
Saito N, Takahata K, Yamakado H, Sawamoto N, Saito S, Takahashi R, Murai T, Takahashi H Saito N, Takahata K, Yamakado H, Sawamoto N, Saito S, Takahashi R, Murai T, Takahashi H Saito N, Takahata K, Yamakado H, Sawamoto N, Saito S, Takahashi R, Murai T, Takahashi H Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures. Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures. Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures. Scientific reports, 7, 1, 8019 Scientific reports, 7, 1, 8019 Scientific reports, 7, 1, 8019 2017/08 公開
Uemura MT, Asano T, Hikawa R, Yamakado H, Takahashi R Uemura MT, Asano T, Hikawa R, Yamakado H, Takahashi R Uemura MT, Asano T, Hikawa R, Yamakado H, Takahashi R Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity. Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity. Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity. Neuroscience research, 124, 25-32 Neuroscience research, 124, 25-32 Neuroscience research, 124, 25-32 2017/06 公開
Kikuchi T, Morizane A, Doi D, Okita K, Nakagawa M, Yamakado H, Inoue H, Takahashi R, Takahashi J Kikuchi T, Morizane A, Doi D, Okita K, Nakagawa M, Yamakado H, Inoue H, Takahashi R, Takahashi J Kikuchi T, Morizane A, Doi D, Okita K, Nakagawa M, Yamakado H, Inoue H, Takahashi R, Takahashi J Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains. Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains. Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains. Journal of neuroscience research, 95, 9, 1829-1837 Journal of neuroscience research, 95, 9, 1829-1837 Journal of neuroscience research, 95, 9, 1829-1837 2017/02 公開
Kinoshita H, Yamakado H, Kitano T, Kitamura A, Yamashita H, Miyamoto M, Hitomi T, Okada T, Nakamoto Y, Sawamoto N, Takaori-Kondo A, Takahashi R Kinoshita H, Yamakado H, Kitano T, Kitamura A, Yamashita H, Miyamoto M, Hitomi T, Okada T, Nakamoto Y, Sawamoto N, Takaori-Kondo A, Takahashi R Kinoshita H, Yamakado H, Kitano T, Kitamura A, Yamashita H, Miyamoto M, Hitomi T, Okada T, Nakamoto Y, Sawamoto N, Takaori-Kondo A, Takahashi R Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases. Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases. Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases. Journal of neurology, 263, 9, 1719-1726 Journal of neurology, 263, 9, 1719-1726 Journal of neurology, 263, 9, 1719-1726 2016/06 公開
Hamatani M, Jingami N, Uemura K, Nakasone N, Kinoshita H, Yamakado H, Ninomiya H, Takahashi R Hamatani M, Jingami N, Uemura K, Nakasone N, Kinoshita H, Yamakado H, Ninomiya H, Takahashi R Hamatani M, Jingami N, Uemura K, Nakasone N, Kinoshita H, Yamakado H, Ninomiya H, Takahashi R A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome. A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome. A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome. Rinsho shinkeigaku = Clinical neurology, 56, 6, 424-429 Rinsho shinkeigaku = Clinical neurology, 56, 6, 424-429 Rinsho shinkeigaku = Clinical neurology, 56, 6, 424-429 2016/06 公開
Uemura N, Koike M, Ansai S, Kinoshita M, Ishikawa-Fujiwara T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R. Uemura N, Koike M, Ansai S, Kinoshita M, Ishikawa-Fujiwara T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R. Uemura N, Koike M, Ansai S, Kinoshita M, Ishikawa-Fujiwara T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R. Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein. Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein. Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein. PLoS Genet, 11, 4, e1005065 PLoS Genet, 11, 4, e1005065 PLoS Genet, 11, 4, e1005065 2015/04 英語 研究論文(学術雑誌) 公開
Yamakado H Yamakado H Yamakado H Advance in PD research explored a new field on ubiquitin biology. Advance in PD research explored a new field on ubiquitin biology. Advance in PD research explored a new field on ubiquitin biology. Movement disorders : official journal of the Movement Disorder Society, 29, 10, 1243 Movement disorders : official journal of the Movement Disorder Society, 29, 10, 1243 Movement disorders : official journal of the Movement Disorder Society, 29, 10, 1243 2014/09 英語 公開
Tojima M, Hitomi T, Jingami N, Tanioka K, Yamakado H, Matsumoto R, Takahashi Y, Ikeda A, Takahashi R Tojima M, Hitomi T, Jingami N, Tanioka K, Yamakado H, Matsumoto R, Takahashi Y, Ikeda A, Takahashi R Tojima M, Hitomi T, Jingami N, Tanioka K, Yamakado H, Matsumoto R, Takahashi Y, Ikeda A, Takahashi R [Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody]. [Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody]. [Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody]. Rinsho shinkeigaku = Clinical neurology, 54, 7, 543-549 Rinsho shinkeigaku = Clinical neurology, 54, 7, 543-549 Rinsho shinkeigaku = Clinical neurology, 54, 7, 543-549 2014 英語 公開
Matsui H, Uemura N, Yamakado H, Takeda S, Takahashi R Matsui H, Uemura N, Yamakado H, Takeda S, Takahashi R Matsui H, Uemura N, Yamakado H, Takeda S, Takahashi R Exploring the pathogenetic mechanisms underlying Parkinson's disease in medaka fish. Exploring the pathogenetic mechanisms underlying Parkinson's disease in medaka fish. Exploring the pathogenetic mechanisms underlying Parkinson's disease in medaka fish. Journal of Parkinson's disease, 4, 2, 301-310 Journal of Parkinson's disease, 4, 2, 301-310 Journal of Parkinson's disease, 4, 2, 301-310 2014 英語 公開
Yamakado H, Takahashi R Yamakado H, Takahashi R Yamakado H, Takahashi R The function of parkin: revisited. The function of parkin: revisited. The function of parkin: revisited. Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1936 Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1936 Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1936 2013/12 英語 公開
Takahashi R, Yamakado H Takahashi R, Yamakado H Takahashi R, Yamakado H Genetic correction will be a standard method for the patient-derived ips cell research? Genetic correction will be a standard method for the patient-derived ips cell research? Genetic correction will be a standard method for the patient-derived ips cell research? Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1935 Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1935 Movement disorders : official journal of the Movement Disorder Society, 28, 14, 1935 2013/12 英語 公開
Minakawa EN, Yamakado H, Tanaka A, Uemura K, Takeda S, Takahashi R Minakawa EN, Yamakado H, Tanaka A, Uemura K, Takeda S, Takahashi R Minakawa EN, Yamakado H, Tanaka A, Uemura K, Takeda S, Takahashi R Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction. Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction. Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction. Neuroscience research, 77, 4, 228-233 Neuroscience research, 77, 4, 228-233 Neuroscience research, 77, 4, 228-233 2013/12 英語 公開
Ageta-Ishihara N, Yamakado H, Morita T, Hattori S, Takao K, Miyakawa T, Takahashi R, Kinoshita M Ageta-Ishihara N, Yamakado H, Morita T, Hattori S, Takao K, Miyakawa T, Takahashi R, Kinoshita M Ageta-Ishihara N, Yamakado H, Morita T, Hattori S, Takao K, Miyakawa T, Takahashi R, Kinoshita M Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice. Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice. Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice. Molecular brain, 6, 35 Molecular brain, 6, 35 Molecular brain, 6, 35 2013/08 英語 公開
Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R Matsui H, Gavinio R, Asano T, Uemura N, Ito H, Taniguchi Y, Kobayashi Y, Maki T, Shen J, Takeda S, Uemura K, Yamakado H, Takahashi R PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates. PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates. PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates. Human molecular genetics, 22, 12, 2423-2434 Human molecular genetics, 22, 12, 2423-2434 Human molecular genetics, 22, 12, 2423-2434 2013/06 英語 公開
Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats. Brain : a journal of neurology, 136, Pt 2, 412-432 Brain : a journal of neurology, 136, Pt 2, 412-432 Brain : a journal of neurology, 136, Pt 2, 412-432 2013/02 英語 公開
Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. Neuroscience research, 73, 2, 173-177 Neuroscience research, 73, 2, 173-177 Neuroscience research, 73, 2, 173-177 2012/06 英語 公開
Kondo T, Yamakado H, Kawamata J, Tomimoto H, Hitomi T, Takahashi R, Ikeda A Kondo T, Yamakado H, Kawamata J, Tomimoto H, Hitomi T, Takahashi R, Ikeda A Kondo T, Yamakado H, Kawamata J, Tomimoto H, Hitomi T, Takahashi R, Ikeda A [Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: a case report]. [Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: a case report]. [Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: a case report]. Rinsho shinkeigaku = Clinical neurology, 49, 1, 43-47 Rinsho shinkeigaku = Clinical neurology, 49, 1, 43-47 Rinsho shinkeigaku = Clinical neurology, 49, 1, 43-47 2009/01 英語 公開
Sawada H, Yamakawa K, Yamakado H, Hosokawa R, Ohba M, Miyamoto K, Kawamura T, Shimohama S Sawada H, Yamakawa K, Yamakado H, Hosokawa R, Ohba M, Miyamoto K, Kawamura T, Shimohama S Sawada H, Yamakawa K, Yamakado H, Hosokawa R, Ohba M, Miyamoto K, Kawamura T, Shimohama S Cocaine and phenylephrine eye drop test for Parkinson disease. Cocaine and phenylephrine eye drop test for Parkinson disease. Cocaine and phenylephrine eye drop test for Parkinson disease. JAMA, 293, 8, 932-934 JAMA, 293, 8, 932-934 JAMA, 293, 8, 932-934 2005/02 英語 公開

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タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
若手研究(B) 代表 新しいシヌクレイン遺伝子導入マウスを用いたパーキンソン病発症メカニズムの解明 Investigation of pathomechanism of Parkinson's disease using novel alpha-synuclein-based genetic mice model 2012〜2014
若手研究(B) 代表 iPS細胞を用いた孤発性パーキンソン病の病態解明と標的分子の同定 Investigation of pathomechanism and identification of therapeutic target of Parkinson's disease using iPS cells 2014〜2016
基盤研究(C) 代表 多系統萎縮症の病態解明と治療法の開発 2016〜2019
基盤研究(C) 代表 多系統萎縮症の病態解明と治療法の開発 (平成29年度分) 2017/04/01〜2018/03/31
部局運営(役職等)
役職名 期間
動物実験施設運営委員会 2013/04/01〜2014/03/31
外来医長・看護師長会議 委員 2014/04/01〜