山田 亮

最終更新日時: 2019/06/03 15:03:36

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氏名(漢字/フリガナ/アルファベット表記)
山田 亮/ヤマダ リョウ/Yamada, Ryo
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学研究科附属ゲノム医学センター/統計遺伝学分野/教授
学部兼担
部局 所属 講座等 職名
医学部
学内兼務
部局 所属 講座等 職名
数理解析研究所 数学連携センター 特任教授
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8507 京都市左京区聖護院川原町53 南部総合研究1号館5階 統計遺伝学分野 Unit of Statistical Genetics Center for Genomic Medicine Graduate School of Medicine Kyoto University 53, Syogoin-kawaramachi, Sakyo-ku, Kyoto 606-0815, JAPAN
連絡先電話番号
種別 番号
職場 075-366-7403
全学電子メールアドレス
yamada.ryo.5u @ kyoto-u.ac.jp
所属学会(国内)
学会名(日本語) 学会名(英語)
日本人類遺伝学会
所属学会(海外)
学会名(英語) 国名
International Genetic Epidemiology Society U.S.A.
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 東京大学
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
東京大学 医学部医学科 卒業
出身高等学校
高等学校名 ふりがな
山口県立山口高等学校 やまぐちけんりつやまぐちこうとうがっこう
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
2000/04/01〜2005/03/31 理化学研究所横浜研究所遺伝子多型研究センター SNP Research Center, RIKEN 研究員・上級研究員 Researcher, Senior researcher
2005/04/01〜2007/03/31 京都大学大学院医学研究科 Graduate School of Medicine, Kyoto University 准教授 Associate professor
2007/04/01〜2009/07/31 東京大学医科学研究所 Institute of medical science, University of Tokyo 准教授 Associate professor
2009/08/01〜 京都大学大学院医学研究科 Graduate School of Medicine, Kyoto University 教授 Professor
プロフィール
(日本語)
ゲノム・オミクス研究を進める上での統計解析手法を研究をしています。具体的には、遺伝的多様性と形質多様性とのとらえ方・データ構造に興味をもっています。また、高次元データ、形態・時系列データの解析手法にも重点を置いています。
(英語)
We study statistical methods for genomic and various omic analyses. We are interested in heterogeneity and structure of genetic and phenotypic heterogeneity as well as geometrical/chronological traits and high-dimensional data sets.
使用言語
言語名
英語
個人ホームページ
URL
https://www.facebook.com/statgenetKyoto
http://statgenet-kyotouniv.wikidot.com/
researchmap URL
https://researchmap.jp/7000008855
研究テーマ
(日本語)
遺伝的多様性の計量方法、遺伝因子マッピング
(英語)
Statistical methods to measure genetic heterogeneity and genetic epidemiology.
研究概要
(日本語)
多様性は生物・生命現象の根本ですが、ゲノム学をはじめとする大量データ科学の隆盛とともに、生物の多様性を理解することの重要性が高まっています。健康・疾病も生命個体に現れる多様性そのものであり、医学的見地から生物多様性の理解に挑戦することが求められています。統計遺伝学は生物多様性を遺伝的多様性と環境的多様性との組み合わせとして数理的に表現し解明することを目指します。メンデルの時代からの伝統があるにもかかわらず、日本国内では統計遺伝学の名を冠した講座は極めてまれで、京都大学においても平成21年8月に発足しました。また、21世紀に入って、非常に学際的な色彩が濃くなった学問分野であることも特徴で、数学・統計学・情報科学・計算機学・遺伝学・分子生物学・医学のどれを土台にして取り組むことが可能です。
(英語)
Diversity is a fundamental feature of biology. Recent developments in genomics and related research fields with massive data have provided great opportunities to investigate biological diversity. The concept of health and diseases is an aspect of phenotypic heterogeneity itself, which means medical approach to the diversity is important. Statistical genetics is the study to understand biological diversity by expressing the diversity by combining genetic and environmental components with mathematical methods. Although it has a long and sound history since Gregor Johann Mendel, there are few laboratories titled “statistical genetics” in Japan. This laboratory in graduate school of medicine, Kyoto University, has just started in August, 2009. Another feature of statistical genetics is that it is becoming more and more interdisciplinary encompassing mathematics, statistics, information science, computer science, genetics, molecular biology and medicine and therefore you can start statistical genetics from any one of these basic fields.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
遺伝学 Genetics
統計学 Statistics
疫学 Epidemiology
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Y. Tabara; S. Muro; Y. Takahashi; K. Setoh; T. Kawaguchi; C. Terao; S. Kosugi; A. Sekine; R. Yamada; T. Nakayama; M. Mishima; F. Matsuda Y. Tabara; S. Muro; Y. Takahashi; K. Setoh; T. Kawaguchi; C. Terao; S. Kosugi; A. Sekine; R. Yamada; T. Nakayama; M. Mishima; F. Matsuda Airflow limitation in smokers is associated with arterial stiffness: The Nagahama Study Airflow limitation in smokers is associated with arterial stiffness: The Nagahama Study Atherosclerosis, 232, 1, 59-64 , 232, 1, 59-64 Atherosclerosis, 232, 1, 59-64 2014/01 英語 公開
M. Miyake; K. Yamashiro; Y. Akagi-Kurashige; K. Kumagai; I. Nakata; H. Nakanishi; A. Oishi; A. Tsujikawa; R. Yamada; F. Matsuda; N. Yoshimura M. Miyake; K. Yamashiro; Y. Akagi-Kurashige; K. Kumagai; I. Nakata; H. Nakanishi; A. Oishi; A. Tsujikawa; R. Yamada; F. Matsuda; N. Yoshimura Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia Ophthalmology, 121, 1, 225-233 , 121, 1, 225-233 Ophthalmology, 121, 1, 225-233 2014 英語 公開
S. Nanayakkara; S.T.M.L.D. Senevirathna; T. Abeysekera; R. Chandrajith; N. Ratnatunga; E.D.L. Gunarathne; J. Yan; T. Hitomi; E. Muso; T. Komiya; K.H. Harada; W. Liu; H. Kobayashi; H. Okuda; H. Sawatari; F. Matsuda; R. Yamada; T. Watanabe; H. Miyataka; S. Himeno; A. Koizumi S. Nanayakkara; S.T.M.L.D. Senevirathna; T. Abeysekera; R. Chandrajith; N. Ratnatunga; E.D.L. Gunarathne; J. Yan; T. Hitomi; E. Muso; T. Komiya; K.H. Harada; W. Liu; H. Kobayashi; H. Okuda; H. Sawatari; F. Matsuda; R. Yamada; T. Watanabe; H. Miyataka; S. Himeno; A. Koizumi An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka Journal of Occupational Health, 56, 1, 28-38 , 56, 1, 28-38 Journal of Occupational Health, 56, 1, 28-38 2014 英語 公開
K. Tanizawa; T. Handa; S. Nagai; H. Sato; R. Yamada; I. Ito; T. Kubo; Y. Ito; K. Watanabe; K. Aihara; K. Ikezoe; M. Mishima; T. Izumi K. Tanizawa; T. Handa; S. Nagai; H. Sato; R. Yamada; I. Ito; T. Kubo; Y. Ito; K. Watanabe; K. Aihara; K. Ikezoe; M. Mishima; T. Izumi Interferon regulatory factor 5 polymorphisms in sarcoidosis Interferon regulatory factor 5 polymorphisms in sarcoidosis Modern Rheumatology, 23, 6, 1158-1165 , 23, 6, 1158-1165 Modern Rheumatology, 23, 6, 1158-1165 2013/11 英語 公開
Y. Tabara; Y. Takahashi; K. Setoh; S. Muro; T. Kawaguchi; C. Terao; S. Kosugi; A. Sekine; R. Yamada; M. Mishima; T. Nakayama; F. Matsuda Y. Tabara; Y. Takahashi; K. Setoh; S. Muro; T. Kawaguchi; C. Terao; S. Kosugi; A. Sekine; R. Yamada; M. Mishima; T. Nakayama; F. Matsuda Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: The Nagahama Study Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: The Nagahama Study International Journal of Cardiology, 168, 3, 2673-2677 , 168, 3, 2673-2677 International Journal of Cardiology, 168, 3, 2673-2677 2013/10/03 英語 公開
C. Terao; H. Yoshifuji; A. Kimura; T. Matsumura; K. Ohmura; M. Takahashi; M. Shimizu; T. Kawaguchi; Z. Chen; T.K. Naruse; A. Sato-Otsubo; Y. Ebana; Y. Maejima; H. Kinoshita; K. Murakami; D. Kawabata; Y. Wada; I. Narita; J. Tazaki; Y. Kawaguchi; H. Yamanaka; K. Yurugi; Y. Miura; T. Maekawa; S. Ogawa; I. Komuro; R. Nagai; R. Yamada; Y. Tabara; M. Isobe; T. Mimori; F. Matsuda C. Terao; H. Yoshifuji; A. Kimura; T. Matsumura; K. Ohmura; M. Takahashi; M. Shimizu; T. Kawaguchi; Z. Chen; T.K. Naruse; A. Sato-Otsubo; Y. Ebana; Y. Maejima; H. Kinoshita; K. Murakami; D. Kawabata; Y. Wada; I. Narita; J. Tazaki; Y. Kawaguchi; H. Yamanaka; K. Yurugi; Y. Miura; T. Maekawa; S. Ogawa; I. Komuro; R. Nagai; R. Yamada; Y. Tabara; M. Isobe; T. Mimori; F. Matsuda Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population American Journal of Human Genetics, 93, 2, 289-297 , 93, 2, 289-297 American Journal of Human Genetics, 93, 2, 289-297 2013/08/08 英語 公開
C. Terao; K. Ohmura; Y. Kawaguchi; T. Nishimoto; A. Kawasaki; K. Takehara; H. Furukawa; Y. Kochi; Y. Ota; K. Ikari; S. Sato; S. Tohma; R. Yamada; K. Yamamoto; M. Kubo; H. Yamanaka; M. Kuwana; N. Tsuchiya; F. Matsuda; T. Mimori C. Terao; K. Ohmura; Y. Kawaguchi; T. Nishimoto; A. Kawasaki; K. Takehara; H. Furukawa; Y. Kochi; Y. Ota; K. Ikari; S. Sato; S. Tohma; R. Yamada; K. Yamamoto; M. Kubo; H. Yamanaka; M. Kuwana; N. Tsuchiya; F. Matsuda; T. Mimori PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population Arthritis and Rheumatism, 65, 2, 472-480 , 65, 2, 472-480 Arthritis and Rheumatism, 65, 2, 472-480 2013 英語 公開
C. Terao; M. Hashimoto; K. Yamamoto; K. Murakami; K. Ohmura; R. Nakashima; N. Yamakawa; H. Yoshifuji; N. Yukawa; D. Kawabata; T. Usui; H. Yoshitomi; M. Furu; R. Yamada; F. Matsuda; H. Ito; T. Fujii; T. Mimori C. Terao; M. Hashimoto; K. Yamamoto; K. Murakami; K. Ohmura; R. Nakashima; N. Yamakawa; H. Yoshifuji; N. Yukawa; D. Kawabata; T. Usui; H. Yoshitomi; M. Furu; R. Yamada; F. Matsuda; H. Ito; T. Fujii; T. Mimori Three Groups in the 28 Joints for Rheumatoid Arthritis Synovitis - Analysis Using More than 17,000 Assessments in the KURAMA Database Three Groups in the 28 Joints for Rheumatoid Arthritis Synovitis - Analysis Using More than 17,000 Assessments in the KURAMA Database PLoS ONE, 8, 3 , 8, 3 PLoS ONE, 8, 3 2013 英語 公開
Y. Hamaguchi; M. Fujimoto; T. Matsushita; K. Kaji; K. Komura; M. Hasegawa; M. Kodera; E. Muroi; K. Fujikawa; M. Seishima; H. Yamada; R. Yamada; S. Sato; K. Takehara; M. Kuwana Y. Hamaguchi; M. Fujimoto; T. Matsushita; K. Kaji; K. Komura; M. Hasegawa; M. Kodera; E. Muroi; K. Fujikawa; M. Seishima; H. Yamada; R. Yamada; S. Sato; K. Takehara; M. Kuwana Common and Distinct Clinical Features in Adult Patients with Anti-Aminoacyl-tRNA Synthetase Antibodies: Heterogeneity within the Syndrome Common and Distinct Clinical Features in Adult Patients with Anti-Aminoacyl-tRNA Synthetase Antibodies: Heterogeneity within the Syndrome PLoS ONE, 8, 4 , 8, 4 PLoS ONE, 8, 4 2013 英語 公開
K. Shimane; Y. Kochi; A. Suzuki; Y. Okada; T. Ishii; T. Horita; K. Saito; A. Okamoto; N. Nishimoto; K. Myouzen; M. Kubo; M. Hirakata; T. Sumida; Y. Takasaki; R. Yamada; Y. Nakamura; N. Kamatani; K. Yamamoto K. Shimane; Y. Kochi; A. Suzuki; Y. Okada; T. Ishii; T. Horita; K. Saito; A. Okamoto; N. Nishimoto; K. Myouzen; M. Kubo; M. Hirakata; T. Sumida; Y. Takasaki; R. Yamada; Y. Nakamura; N. Kamatani; K. Yamamoto An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: Effects of *09:01 allele on disease phenotypes An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: Effects of *09:01 allele on disease phenotypes Rheumatology (United Kingdom), 52, 7, 1172-1182 , 52, 7, 1172-1182 Rheumatology (United Kingdom), 52, 7, 1172-1182 2013 英語 公開
Y. Tabara; Y. Takahashi; K. Kohara; K. Setoh; T. Kawaguchi; C. Terao; M. Igase; R. Yamada; S. Kosugi; A. Sekine; T. Miki; T. Nakayama; F. Matsuda Y. Tabara; Y. Takahashi; K. Kohara; K. Setoh; T. Kawaguchi; C. Terao; M. Igase; R. Yamada; S. Kosugi; A. Sekine; T. Miki; T. Nakayama; F. Matsuda Association of longer QT interval with arterial waveform and lower pulse pressure amplification: The nagahama study Association of longer QT interval with arterial waveform and lower pulse pressure amplification: The nagahama study American Journal of Hypertension, 26, 8, 973-980 , 26, 8, 973-980 American Journal of Hypertension, 26, 8, 973-980 2013 英語 公開
M. Narahara; K. Tamaki; R. Yamada M. Narahara; K. Tamaki; R. Yamada Application of permanents of square matrices for DNA identification in multiple-fatality cases Application of permanents of square matrices for DNA identification in multiple-fatality cases BMC Genetics, 14 , 14 BMC Genetics, 14 2013 英語 公開
I. Nakata; K. Yamashiro; T. Kawaguchi; N. Gotoh; H. Nakanishi; Y. Akagi-Kurashige; M. Miyake; A. Tsujikawa; A. Oishi; M. Saito; T. Iida; R. Yamada; F. Matsuda; N. Yoshimura I. Nakata; K. Yamashiro; T. Kawaguchi; N. Gotoh; H. Nakanishi; Y. Akagi-Kurashige; M. Miyake; A. Tsujikawa; A. Oishi; M. Saito; T. Iida; R. Yamada; F. Matsuda; N. Yoshimura Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy Investigative Ophthalmology and Visual Science, 54, 9, 6068-6073 , 54, 9, 6068-6073 Investigative Ophthalmology and Visual Science, 54, 9, 6068-6073 2013 英語 公開
K. Wakai; K. Matsuo; F. Matsuda; R. Yamada; M. Takahashi; T. Kawaguchi; Y. Yatabe; H. Ito; S. Hosono; K. Tajima; M. Naito; E. Morita; G. Yin; T. Sakamoto; N. Takashima; S. Suzuki; N. Nakahata; H. Mikami; K. Ohnaka; Y. Watanabe; K. Arisawa; M. Kubo; N. Hamajima; H. Tanaka K. Wakai; K. Matsuo; F. Matsuda; R. Yamada; M. Takahashi; T. Kawaguchi; Y. Yatabe; H. Ito; S. Hosono; K. Tajima; M. Naito; E. Morita; G. Yin; T. Sakamoto; N. Takashima; S. Suzuki; N. Nakahata; H. Mikami; K. Ohnaka; Y. Watanabe; K. Arisawa; M. Kubo; N. Hamajima; H. Tanaka Genome-wide association study of genetic factors related to confectionery intake: Potential roles of the ADIPOQ gene Genome-wide association study of genetic factors related to confectionery intake: Potential roles of the ADIPOQ gene Obesity, 21, 11, 2413-2419 , 21, 11, 2413-2419 Obesity, 21, 11, 2413-2419 2013 英語 公開
M. Oishi; K. Yamashiro; M. Miyake; Y. Akagi-Kurashige; K. Kumagai; I. Nakata; H. Nakanishi; M. Yoshikawa; A. Oishi; N. Gotoh; A. Tsujikawa; R. Yamada; F. Matsuda; N. Yoshimura M. Oishi; K. Yamashiro; M. Miyake; Y. Akagi-Kurashige; K. Kumagai; I. Nakata; H. Nakanishi; M. Yoshikawa; A. Oishi; N. Gotoh; A. Tsujikawa; R. Yamada; F. Matsuda; N. Yoshimura Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects Investigative Ophthalmology and Visual Science, 54, 12, 7492-7497 , 54, 12, 7492-7497 Investigative Ophthalmology and Visual Science, 54, 12, 7492-7497 2013 英語 公開
M. Miyake; K. Yamashiro; H. Nakanishi; I. Nakata; Y. Akagi-Kurashige; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; R. Yamada; F. Matsuda; N. Yoshimura M. Miyake; K. Yamashiro; H. Nakanishi; I. Nakata; Y. Akagi-Kurashige; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; R. Yamada; F. Matsuda; N. Yoshimura Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort Molecular Vision, 19, 1074-1081 , 19, 1074-1081 Molecular Vision, 19, 1074-1081 2013 英語 公開
T. Kawaguchi; Y. Sumida; A. Umemura; K. Matsuo; M. Takahashi; T. Takamura; K. Yasui; T. Saibara; E. Hashimoto; M. Kawanaka; S. Watanabe; S. Kawata; Y. Imai; M. Kokubo; T. Shima; H. Park; H. Tanaka; K. Tajima; R. Yamada; F. Matsuda; T. Okanoue T. Kawaguchi; Y. Sumida; A. Umemura; K. Matsuo; M. Takahashi; T. Takamura; K. Yasui; T. Saibara; E. Hashimoto; M. Kawanaka; S. Watanabe; S. Kawata; Y. Imai; M. Kokubo; T. Shima; H. Park; H. Tanaka; K. Tajima; R. Yamada; F. Matsuda; T. Okanoue Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese PLoS ONE, 7, 6 , 7, 6 PLoS ONE, 7, 6 2012/06/14 英語 公開
Y. Okada; C. Terao; K. Ikari; Y. Kochi; K. Ohmura; A. Suzuki; T. Kawaguchi; E.A. Stahl; F.A.S. Kurreeman; N. Nishida; H. Ohmiya; K. Myouzen; M. Takahashi; T. Sawada; Y. Nishioka; M. Yukioka; T. Matsubara; S. Wakitani; R. Teshima; S. Tohma; K. Takasugi; K. Shimada; A. Murasawa; S. Honjo; K. Matsuo; H. Tanaka; K. Tajima; T. Suzuki; T. Iwamoto; Y. Kawamura; H. Tanii; Y. Okazaki; T. Sasaki; P.K. Gregersen; L. Padyukov; J. Worthington; K.A. Siminovitch; M. Lathrop; A. Taniguchi; A. Takahashi; K. Tokunaga; M. Kubo; Y. Nakamura; N. Kamatani; T. Mimori; R.M. Plenge; H. Yamanaka; S. Momohara; R. Yamada; F. Matsuda; K. Yamamoto Y. Okada; C. Terao; K. Ikari; Y. Kochi; K. Ohmura; A. Suzuki; T. Kawaguchi; E.A. Stahl; F.A.S. Kurreeman; N. Nishida; H. Ohmiya; K. Myouzen; M. Takahashi; T. Sawada; Y. Nishioka; M. Yukioka; T. Matsubara; S. Wakitani; R. Teshima; S. Tohma; K. Takasugi; K. Shimada; A. Murasawa; S. Honjo; K. Matsuo; H. Tanaka; K. Tajima; T. Suzuki; T. Iwamoto; Y. Kawamura; H. Tanii; Y. Okazaki; T. Sasaki; P.K. Gregersen; L. Padyukov; J. Worthington; K.A. Siminovitch; M. Lathrop; A. Taniguchi; A. Takahashi; K. Tokunaga; M. Kubo; Y. Nakamura; N. Kamatani; T. Mimori; R.M. Plenge; H. Yamanaka; S. Momohara; R. Yamada; F. Matsuda; K. Yamamoto Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population Nature Genetics, 44, 5, 511-+ , 44, 5, 511-+ Nature Genetics, 44, 5, 511-+ 2012/05 英語 公開
R. Meziani; R. Yamada; M. Takahashi; K. Ohigashi; A. Morinobu; C. Terao; H. Hiratani; K. Ohmura; M. Yamaguchi; T. Nomura; A. Vasilescu; M. Kokubo; V. Renault; K. Hirosawa; C. Ratanajaraya; S. Heath; T. Mimori; S. Sakaguchi; M. Lathrop; I. Melchers; S. Kumagai; F. Matsuda R. Meziani; R. Yamada; M. Takahashi; K. Ohigashi; A. Morinobu; C. Terao; H. Hiratani; K. Ohmura; M. Yamaguchi; T. Nomura; A. Vasilescu; M. Kokubo; V. Renault; K. Hirosawa; C. Ratanajaraya; S. Heath; T. Mimori; S. Sakaguchi; M. Lathrop; I. Melchers; S. Kumagai; F. Matsuda A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations Modern Rheumatology, 22, 1, 52-58 , 22, 1, 52-58 Modern Rheumatology, 22, 1, 52-58 2012/02 英語 公開
R. Onuki; R. Yamada; R. Yamaguchi; M. Kanehisa; T. Shibuya R. Onuki; R. Yamada; R. Yamaguchi; M. Kanehisa; T. Shibuya Population model-based inter-diplotype similarity measure for accurate diplotype clustering Population model-based inter-diplotype similarity measure for accurate diplotype clustering Journal of Computational Biology, 19, 1, 55-67 , 19, 1, 55-67 Journal of Computational Biology, 19, 1, 55-67 2012 英語 公開
Y. Okada; K. Shimane; Y. Kochi; T. Tahira; A. Suzuki; K. Higasa; A. Takahashi; T. Horita; T. Atsumi; T. Ishii; A. Okamoto; K. Fujio; M. Hirakata; H. Amano; Y. Kondo; S. Ito; K. Takada; A. Mimori; K. Saito; M. Kamachi; Y. Kawaguchi; K. Ikari; O.W. Mohammed; K. Matsuda; C. Terao; K. Ohmura; K. Myouzen; N. Hosono; T. Tsunoda; N. Nishimoto; T. Mimori; F. Matsuda; Y. Tanaka; T. Sumida; H. Yamanaka; Y. Takasaki; T. Koike; T. Horiuchi; K. Hayashi; M. Kubo; N. Kamatani; R. Yamada; Y. Nakamura; K. Yamamoto Y. Okada; K. Shimane; Y. Kochi; T. Tahira; A. Suzuki; K. Higasa; A. Takahashi; T. Horita; T. Atsumi; T. Ishii; A. Okamoto; K. Fujio; M. Hirakata; H. Amano; Y. Kondo; S. Ito; K. Takada; A. Mimori; K. Saito; M. Kamachi; Y. Kawaguchi; K. Ikari; O.W. Mohammed; K. Matsuda; C. Terao; K. Ohmura; K. Myouzen; N. Hosono; T. Tsunoda; N. Nishimoto; T. Mimori; F. Matsuda; Y. Tanaka; T. Sumida; H. Yamanaka; Y. Takasaki; T. Koike; T. Horiuchi; K. Hayashi; M. Kubo; N. Kamatani; R. Yamada; Y. Nakamura; K. Yamamoto A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese PLoS Genetics, 8, 1 , 8, 1 PLoS Genetics, 8, 1 2012 英語 公開
I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; Y. Akagi-Kurashige; A. Tsujikawa; A. Otani; M. Saito; T. Iida; A. Oishi; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; Y. Akagi-Kurashige; A. Tsujikawa; A. Otani; M. Saito; T. Iida; A. Oishi; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura Significance of C2/CFB variants in age-related macular degeneration and polypoidal choroidal vasculopathy in a Japanese population Significance of C2/CFB variants in age-related macular degeneration and polypoidal choroidal vasculopathy in a Japanese population Investigative Ophthalmology and Visual Science, 53, 2, 794-798 , 53, 2, 794-798 Investigative Ophthalmology and Visual Science, 53, 2, 794-798 2012 英語 公開
Y. Akagi-Kurashige; K. Kumagai; K. Yamashiro; H. Nakanishi; I. Nakata; M. Miyake; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; R. Yamada; F. Matsuda; N. Yoshimura Y. Akagi-Kurashige; K. Kumagai; K. Yamashiro; H. Nakanishi; I. Nakata; M. Miyake; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; R. Yamada; F. Matsuda; N. Yoshimura Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes Investigative Ophthalmology and Visual Science, 53, 4, 2349-2353 , 53, 4, 2349-2353 Investigative Ophthalmology and Visual Science, 53, 4, 2349-2353 2012 英語 公開
C. Terao; K. Ohmura; K. Ikari; Y. Kochi; E. Maruya; M. Katayama; K. Yurugi; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; K. Matsuo; K. Tajima; A. Suzuki; K. Yamamoto; S. Momohara; H. Yamanaka; R. Yamada; H. Saji; F. Matsuda; T. Mimori C. Terao; K. Ohmura; K. Ikari; Y. Kochi; E. Maruya; M. Katayama; K. Yurugi; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; K. Matsuo; K. Tajima; A. Suzuki; K. Yamamoto; S. Momohara; H. Yamanaka; R. Yamada; H. Saji; F. Matsuda; T. Mimori ACPA-negative RA consists of two genetically distinct subsets based on rf positivity in japanese ACPA-negative RA consists of two genetically distinct subsets based on rf positivity in japanese PLoS ONE, 7, 7 , 7, 7 PLoS ONE, 7, 7 2012 英語 公開
B. Desalegn; H. Beyene; R. Yamada B. Desalegn; H. Beyene; R. Yamada Patients-to-healthcare workers HIV transmission risk from sharp injuries, Southern Ethiopia Patients-to-healthcare workers HIV transmission risk from sharp injuries, Southern Ethiopia Sahara J, 9, 1, 1-5 , 9, 1, 1-5 Sahara J, 9, 1, 1-5 2012 英語 公開
V.J.M. Verhoeven; P.G. Hysi; S.-M. Saw; V. Vitart; A. Mirshahi; J.A. Guggenheim; M.F. Cotch; K. Yamashiro; P.N. Baird; D.A. Mackey; R. Wojciechowski; M. Kamran Ikram; A.W. Hewitt; P. Duggal; S. Janmahasatian; C.-C. Khor; Q. Fan; X. Zhou; T.L. Young; E.-S. Tai; L.-K. Goh; Y.-J. Li; T. Aung; E. Vithana; Y.-Y. Teo; W. Tay; X. Sim; I. Rudan; C. Hayward; A.F. Wright; O. Polasek; H. Campbell; J.F. Wilson; B.W. Fleck; I. Nakata; N. Yoshimura; R. Yamada; F. Matsuda; K. Ohno-Matsui; A. Nag; G. McMahon; B. St. Pourcain; Y. Lu; J.S. Rahi; P.M. Cumberland; S. Bhattacharya; C.L. Simpson; L.D. Atwood; X. Li; L.J. Raffel; F. Murgia; L. Portas; D.D.G. Despriet; L.M.E. Van Koolwijk; C. Wolfram; K.J. Lackner; A. Tönjes; R. Mägi; T. Lehtimäki; M. Kähönen; T. Esko; A. Metspalu; T. Rantanen; O. Pärssinen; B.E. Klein; T. Meitinger; T.D. Spector; B.A. Oostra; A.V. Smith; P.T.V.M. De Jong; A. Hofman; N. Amin; L.C. Karssen; F. Rivadeneira; J.R. Vingerling; G. Eiríksdóttir; V. Gudnason; A. Döring; T. Bettecken; A.G. Uitterlinden; C. Williams; T. Zeller; R. Castagné; K. Oexle; C.M. Van Duijn; S.K. Iyengar; P. Mitchell; J.J. Wang; R. Höhn; N. Pfeiffer; J.E. Bailey-Wilson; D. Stambolian; T.-Y. Wong; C.J. Hammond; C.C.W. Klaver V.J.M. Verhoeven; P.G. Hysi; S.-M. Saw; V. Vitart; A. Mirshahi; J.A. Guggenheim; M.F. Cotch; K. Yamashiro; P.N. Baird; D.A. Mackey; R. Wojciechowski; M. Kamran Ikram; A.W. Hewitt; P. Duggal; S. Janmahasatian; C.-C. Khor; Q. Fan; X. Zhou; T.L. Young; E.-S. Tai; L.-K. Goh; Y.-J. Li; T. Aung; E. Vithana; Y.-Y. Teo; W. Tay; X. Sim; I. Rudan; C. Hayward; A.F. Wright; O. Polasek; H. Campbell; J.F. Wilson; B.W. Fleck; I. Nakata; N. Yoshimura; R. Yamada; F. Matsuda; K. Ohno-Matsui; A. Nag; G. McMahon; B. St. Pourcain; Y. Lu; J.S. Rahi; P.M. Cumberland; S. Bhattacharya; C.L. Simpson; L.D. Atwood; X. Li; L.J. Raffel; F. Murgia; L. Portas; D.D.G. Despriet; L.M.E. Van Koolwijk; C. Wolfram; K.J. Lackner; A. Tönjes; R. Mägi; T. Lehtimäki; M. Kähönen; T. Esko; A. Metspalu; T. Rantanen; O. Pärssinen; B.E. Klein; T. Meitinger; T.D. Spector; B.A. Oostra; A.V. Smith; P.T.V.M. De Jong; A. Hofman; N. Amin; L.C. Karssen; F. Rivadeneira; J.R. Vingerling; G. Eiríksdóttir; V. Gudnason; A. Döring; T. Bettecken; A.G. Uitterlinden; C. Williams; T. Zeller; R. Castagné; K. Oexle; C.M. Van Duijn; S.K. Iyengar; P. Mitchell; J.J. Wang; R. Höhn; N. Pfeiffer; J.E. Bailey-Wilson; D. Stambolian; T.-Y. Wong; C.J. Hammond; C.C.W. Klaver Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium Human Genetics, 131, 9, 1467-1480 , 131, 9, 1467-1480 Human Genetics, 131, 9, 1467-1480 2012 英語 公開
K. Myouzen; Y. Kochi; Y. Okada; C. Terao; A. Suzuki; K. Ikari; T. Tsunoda; A. Takahashi; M. Kubo; A. Taniguchi; F. Matsuda; K. Ohmura; S. Momohara; T. Mimori; H. Yamanaka; N. Kamatani; R. Yamada; Y. Nakamura; K. Yamamoto K. Myouzen; Y. Kochi; Y. Okada; C. Terao; A. Suzuki; K. Ikari; T. Tsunoda; A. Takahashi; M. Kubo; A. Taniguchi; F. Matsuda; K. Ohmura; S. Momohara; T. Mimori; H. Yamanaka; N. Kamatani; R. Yamada; Y. Nakamura; K. Yamamoto Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese PLoS Genetics, 8, 9 , 8, 9 PLoS Genetics, 8, 9 2012 英語 公開
K. Yoshimura; T. Nakayama; A. Sekine; F. Matsuda; S. Kosugi; R. Yamada; Y. Shimizu; A. Kanematsu; K. Yoshimura; O. Ogawa K. Yoshimura; T. Nakayama; A. Sekine; F. Matsuda; S. Kosugi; R. Yamada; Y. Shimizu; A. Kanematsu; K. Yoshimura; O. Ogawa B-type natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women B-type natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women Neurourology and Urodynamics, 31, 8, 1266-1271 , 31, 8, 1266-1271 Neurourology and Urodynamics, 31, 8, 1266-1271 2012 英語 公開
C. Terao; K. Ohmura; Y. Kochi; K. Ikari; E. Maruya; M. Katayama; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; K. Matsuo; K. Tajima; A. Suzuki; K. Yamamoto; S. Momohara; H. Yamanaka; R. Yamada; H. Saji; F. Matsuda; T. Mimori C. Terao; K. Ohmura; Y. Kochi; K. Ikari; E. Maruya; M. Katayama; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; K. Matsuo; K. Tajima; A. Suzuki; K. Yamamoto; S. Momohara; H. Yamanaka; R. Yamada; H. Saji; F. Matsuda; T. Mimori A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects Annals of the Rheumatic Diseases, 70, 12, 2134-2139 , 70, 12, 2134-2139 Annals of the Rheumatic Diseases, 70, 12, 2134-2139 2011/12 英語 公開
C. Ratanajaraya; H. Nishiyama; M. Takahashi; T. Kawaguchi; R. Saito; Y. Mikami; M. Suyama; M. Lathrop; R. Yamada; O. Ogawa; F. Matsuda C. Ratanajaraya; H. Nishiyama; M. Takahashi; T. Kawaguchi; R. Saito; Y. Mikami; M. Suyama; M. Lathrop; R. Yamada; O. Ogawa; F. Matsuda A polymorphism of the POLG2 gene is genetically associated with the invasiveness of urinary bladder cancer in Japanese males A polymorphism of the POLG2 gene is genetically associated with the invasiveness of urinary bladder cancer in Japanese males Journal of Human Genetics, 56, 8, 572-576 , 56, 8, 572-576 Journal of Human Genetics, 56, 8, 572-576 2011/08 英語 公開
C. Terao; R. Yamada; K. Ohmura; M. Takahashi; T. Kawaguchi; Y. Kochi; Y. Okada; Y. Nakamura; K. Yamamoto; I. Melchers; M. Lathrop; T. Mimori; F. Matsuda C. Terao; R. Yamada; K. Ohmura; M. Takahashi; T. Kawaguchi; Y. Kochi; Y. Okada; Y. Nakamura; K. Yamamoto; I. Melchers; M. Lathrop; T. Mimori; F. Matsuda The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population Human Molecular Genetics, 20, 13, 2680-2685 , 20, 13, 2680-2685 Human Molecular Genetics, 20, 13, 2680-2685 2011/07/01 英語 公開
I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; A. Tsujikawa; A. Otani; S. Ooto; H. Tamura; M. Saito; K. Saito; T. Iida; A. Oishi; Y. Kurimoto; F. Matsuda; N. Yoshimura I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; A. Tsujikawa; A. Otani; S. Ooto; H. Tamura; M. Saito; K. Saito; T. Iida; A. Oishi; Y. Kurimoto; F. Matsuda; N. Yoshimura Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy Ophthalmology, 118, 7, 1408-1415 , 118, 7, 1408-1415 Ophthalmology, 118, 7, 1408-1415 2011/07 英語 公開
Y. Kochi; M.M. Thabet; A. Suzuki; Y. Okada; N.A. Daha; R.E.M. Toes; T.W.J. Huizinga; K. Myouzen; M. Kubo; R. Yamada; Y. Nakamura; K. Yamamoto Y. Kochi; M.M. Thabet; A. Suzuki; Y. Okada; N.A. Daha; R.E.M. Toes; T.W.J. Huizinga; K. Myouzen; M. Kubo; R. Yamada; Y. Nakamura; K. Yamamoto PADI4 polymorphism predisposes male smokers to rheumatoid arthritis PADI4 polymorphism predisposes male smokers to rheumatoid arthritis Annals of the Rheumatic Diseases, 70, 3, 512-515 , 70, 3, 512-515 Annals of the Rheumatic Diseases, 70, 3, 512-515 2011 英語 公開
I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; A. Tsujikawa; A. Otani; M. Saito; T. Iida; A. Oishi; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura I. Nakata; K. Yamashiro; R. Yamada; N. Gotoh; H. Nakanishi; H. Hayashi; A. Tsujikawa; A. Otani; M. Saito; T. Iida; A. Oishi; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura Association between the serping1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in japanese Association between the serping1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in japanese PLoS ONE, 6, 4 , 6, 4 PLoS ONE, 6, 4 2011 英語 公開
R. Cui; Y. Okada; S.G. Jang; J.L. Ku; J.G. Park; Y. Kamatani; N. Hosono; T. Tsunoda; V. Kumar; C. Tanikawa; N. Kamatani; R. Yamada; M. Kubo; Y. Nakamura; K. Matsuda R. Cui; Y. Okada; S.G. Jang; J.L. Ku; J.G. Park; Y. Kamatani; N. Hosono; T. Tsunoda; V. Kumar; C. Tanikawa; N. Kamatani; R. Yamada; M. Kubo; Y. Nakamura; K. Matsuda Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population Gut, 60, 6, 799-805 , 60, 6, 799-805 Gut, 60, 6, 799-805 2011 英語 公開
C. Terao; K. Ohmura; M. Katayama; M. Takahashi; M. Kokubo; G. Diop; Y. Toda; N. Yamamoto; R. Shinkura; M. Shimizu; I. Gut; S. Heath; I. Melchers; T. Manabe; M. Lathrop; T. Mimori; R. Yamada; F. Matsuda C. Terao; K. Ohmura; M. Katayama; M. Takahashi; M. Kokubo; G. Diop; Y. Toda; N. Yamamoto; R. Shinkura; M. Shimizu; I. Gut; S. Heath; I. Melchers; T. Manabe; M. Lathrop; T. Mimori; R. Yamada; F. Matsuda Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis-a genome-wide study combined with immunological analyses Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis-a genome-wide study combined with immunological analyses PLoS ONE, 6, 6 , 6, 6 PLoS ONE, 6, 6 2011 英語 公開
H. Hayashi; K. Yamashiro; H. Nakanishi; I. Nakata; Y. Kurashige; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; M. Ozaki; R. Yamada; F. Matsuda; N. Yoshimura H. Hayashi; K. Yamashiro; H. Nakanishi; I. Nakata; Y. Kurashige; A. Tsujikawa; M. Moriyama; K. Ohno-Matsui; M. Mochizuki; M. Ozaki; R. Yamada; F. Matsuda; N. Yoshimura Association of 15q14 and 15q25 with high myopia in Japanese Association of 15q14 and 15q25 with high myopia in Japanese Investigative Ophthalmology and Visual Science, 52, 7, 4853-4858 , 52, 7, 4853-4858 Investigative Ophthalmology and Visual Science, 52, 7, 4853-4858 2011 英語 公開
M. Matsuse; M. Takahashi; N. Mitsutake; E. Nishihara; M. Hirokawa; T. Kawaguchi; T. Rogounovitch; V. Saenko; A. Bychkov; K. Suzuki; K. Matsuo; K. Tajima; A. Miyauchi; R. Yamada; F. Matsuda; S. Yamashita M. Matsuse; M. Takahashi; N. Mitsutake; E. Nishihara; M. Hirokawa; T. Kawaguchi; T. Rogounovitch; V. Saenko; A. Bychkov; K. Suzuki; K. Matsuo; K. Tajima; A. Miyauchi; R. Yamada; F. Matsuda; S. Yamashita The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population Journal of Medical Genetics, 48, 9, 645-648 , 48, 9, 645-648 Journal of Medical Genetics, 48, 9, 645-648 2011 英語 公開
K. Yamashiro; K. Mori; I. Nakata; T. Tsuchihashi; K. Horie-Inoue; H. Nakanishi; A. Tsujikawa; M. Saito; T. Iida; R. Yamada; F. Matsuda; S. Inoue; T. Awata; S. Yoneya; N. Yoshimura K. Yamashiro; K. Mori; I. Nakata; T. Tsuchihashi; K. Horie-Inoue; H. Nakanishi; A. Tsujikawa; M. Saito; T. Iida; R. Yamada; F. Matsuda; S. Inoue; T. Awata; S. Yoneya; N. Yoshimura Association of elastin gene polymorphism to age-related macular degeneration and polypoidal choroidal vasculopathy Association of elastin gene polymorphism to age-related macular degeneration and polypoidal choroidal vasculopathy Investigative Ophthalmology and Visual Science, 52, 12, 8780-8784 , 52, 12, 8780-8784 Investigative Ophthalmology and Visual Science, 52, 12, 8780-8784 2011 英語 公開
K. Ohmura; C. Terao; E. Maruya; M. Katayama; K. Matoba; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; S. Tohma; K. Matsuo; K. Tajima; N. Yukawa; D. Kawabata; T. Nojima; T. Fujii; R. Yamada; H. Saji; F. Matsuda; T. Mimori K. Ohmura; C. Terao; E. Maruya; M. Katayama; K. Matoba; K. Shimada; A. Murasawa; S. Honjo; K. Takasugi; S. Tohma; K. Matsuo; K. Tajima; N. Yukawa; D. Kawabata; T. Nojima; T. Fujii; R. Yamada; H. Saji; F. Matsuda; T. Mimori Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: A definitive study using only bone-erosive ACPA-negative rheumatoid arthritis Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: A definitive study using only bone-erosive ACPA-negative rheumatoid arthritis Rheumatology, 49, 12, 2298-2304 , 49, 12, 2298-2304 Rheumatology, 49, 12, 2298-2304 2010/12 英語 公開
K. Hirosawa; T. Kawaguchi; F. Matsuda; R. Yamada K. Hirosawa; T. Kawaguchi; F. Matsuda; R. Yamada Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables Genetic Epidemiology, 34, 6, 543-551 , 34, 6, 543-551 Genetic Epidemiology, 34, 6, 543-551 2010/09 英語 公開
M. Takahashi; V.A. Saenko; T.I. Rogounovitch; T. Kawaguchi; V.M. Drozd; H. Takigawa-Imamura; N.M. Akulevich; C. Ratanajaraya; N. Mitsutake; N. Takamura; L.I. Danilova; M.L. Lushchik; Y.E. Demidchik; S. Heath; R. Yamada; M. Lathrop; F. Matsuda; S. Yamashita M. Takahashi; V.A. Saenko; T.I. Rogounovitch; T. Kawaguchi; V.M. Drozd; H. Takigawa-Imamura; N.M. Akulevich; C. Ratanajaraya; N. Mitsutake; N. Takamura; L.I. Danilova; M.L. Lushchik; Y.E. Demidchik; S. Heath; R. Yamada; M. Lathrop; F. Matsuda; S. Yamashita The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl Human Molecular Genetics, 19, 12, 2516-2523 , 19, 12, 2516-2523 Human Molecular Genetics, 19, 12, 2516-2523 2010/06/15 英語 公開
K. Shimane; Y. Kochi; T. Horita; K. Ikari; H. Amano; M. Hirakata; A. Okamoto; R. Yamada; K. Myouzen; A. Suzuki; M. Kubo; T. Atsumi; T. Koike; Y. Takasaki; S. Momohara; H. Yamanaka; Y. Nakamura; K. Yamamoto K. Shimane; Y. Kochi; T. Horita; K. Ikari; H. Amano; M. Hirakata; A. Okamoto; R. Yamada; K. Myouzen; A. Suzuki; M. Kubo; T. Atsumi; T. Koike; Y. Takasaki; S. Momohara; H. Yamanaka; Y. Nakamura; K. Yamamoto The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the japanese population The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the japanese population Arthritis and Rheumatism, 62, 2, 574-579 , 62, 2, 574-579 Arthritis and Rheumatism, 62, 2, 574-579 2010 英語 公開
Y. Kochi; A. Suzuki; R. Yamada; K. Yamamoto Y. Kochi; A. Suzuki; R. Yamada; K. Yamamoto Ethnogenetic heterogeneity of rheumatoid arthritisimplications for pathogenesis Ethnogenetic heterogeneity of rheumatoid arthritisimplications for pathogenesis Nature Reviews Rheumatology, 6, 5, 290-295 , 6, 5, 290-295 Nature Reviews Rheumatology, 6, 5, 290-295 2010 英語 公開
Y. Kochi; Y. Okada; A. Suzuki; K. Ikari; C. Terao; A. Takahashi; K. Yamazaki; N. Hosono; K. Myouzen; T. Tsunoda; N. Kamatani; T. Furuichi; S. Ikegawa; K. Ohmura; T. Mimori; F. Matsuda; T. Iwamoto; S. Momohara; H. Yamanaka; R. Yamada; M. Kubo; Y. Nakamura; K. Yamamoto Y. Kochi; Y. Okada; A. Suzuki; K. Ikari; C. Terao; A. Takahashi; K. Yamazaki; N. Hosono; K. Myouzen; T. Tsunoda; N. Kamatani; T. Furuichi; S. Ikegawa; K. Ohmura; T. Mimori; F. Matsuda; T. Iwamoto; S. Momohara; H. Yamanaka; R. Yamada; M. Kubo; Y. Nakamura; K. Yamamoto A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility Nature Genetics, 42, 6, 515-519 , 42, 6, 515-519 Nature Genetics, 42, 6, 515-519 2010 英語 公開
K. Myouzen; Y. Kochi; K. Shimane; K. Fujio; T. Okamura; Y. Okada; A. Suzuki; T. Atsumi; S. Ito; K. Takada; A. Mimori; S. Ikegawa; R. Yamada; Y. Nakamura; K. Yamamoto K. Myouzen; Y. Kochi; K. Shimane; K. Fujio; T. Okamura; Y. Okada; A. Suzuki; T. Atsumi; S. Ito; K. Takada; A. Mimori; S. Ikegawa; R. Yamada; Y. Nakamura; K. Yamamoto Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus Human Molecular Genetics, 19, 11, 2313-2320 , 19, 11, 2313-2320 Human Molecular Genetics, 19, 11, 2313-2320 2010 英語 公開
H. Nakanishi; N. Gotoh; R. Yamada; K. Yamashiro; A. Otani; H. Hayashi; A. Tsujikawa; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura H. Nakanishi; N. Gotoh; R. Yamada; K. Yamashiro; A. Otani; H. Hayashi; A. Tsujikawa; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population ARMS2/HTRA1 and CFH polymorphisms are not associated with choroidal neovascularization in highly myopic eyes of the elderly Japanese population Eye, 24, 6, 1078-1084 , 24, 6, 1078-1084 Eye, 24, 6, 1078-1084 2010 英語 公開
Y. Okada; A. Suzuki; R. Yamada; Y. Kochi; K. Shimane; K. Myouzen; M. Kubo; Y. Nakamura; K. Yamamoto Y. Okada; A. Suzuki; R. Yamada; Y. Kochi; K. Shimane; K. Myouzen; M. Kubo; Y. Nakamura; K. Yamamoto HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis Annals of the Rheumatic Diseases, 69, 8, 1569-1570 , 69, 8, 1569-1570 Annals of the Rheumatic Diseases, 69, 8, 1569-1570 2010 英語 公開
H. Nakanishi; H. Hayashi; R. Yamada; K. Yamashiro; I. Nakata; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Ozaki; S. Yoshitake; S. Kuriyama; M. Saito; T. Iida; K. Matsuo; F. Matsuda; N. Yoshimura H. Nakanishi; H. Hayashi; R. Yamada; K. Yamashiro; I. Nakata; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Ozaki; S. Yoshitake; S. Kuriyama; M. Saito; T. Iida; K. Matsuo; F. Matsuda; N. Yoshimura Single-nucleotide polymorphisms in the promoter region of matrix metalloproteinase-1, -2, and -3 in Japanese with high myopia Single-nucleotide polymorphisms in the promoter region of matrix metalloproteinase-1, -2, and -3 in Japanese with high myopia Investigative Ophthalmology and Visual Science, 51, 9, 4432-4436 , 51, 9, 4432-4436 Investigative Ophthalmology and Visual Science, 51, 9, 4432-4436 2010 英語 公開
M. Tsuda; R. Kawaida; K. Kobayashi; A. Shinagawa; T. Sawada; R. Yamada; K. Yamamoto; T. Aigaki M. Tsuda; R. Kawaida; K. Kobayashi; A. Shinagawa; T. Sawada; R. Yamada; K. Yamamoto; T. Aigaki POSH promotes cell survival in Drosophila and in human RASF cells POSH promotes cell survival in Drosophila and in human RASF cells FEBS Letters, 584, 22, 4689-4694 , 584, 22, 4689-4694 FEBS Letters, 584, 22, 4689-4694 2010 英語 公開
H. Hayashi; K. Yamashiro; N. Gotoh; H. Nakanishi; I. Nakata; A. Tsujikawa; A. Otani; M. Saito; T. Iida; K. Matsuo; K. Tajima; R. Yamada; N. Yoshimura H. Hayashi; K. Yamashiro; N. Gotoh; H. Nakanishi; I. Nakata; A. Tsujikawa; A. Otani; M. Saito; T. Iida; K. Matsuo; K. Tajima; R. Yamada; N. Yoshimura CFH and ARMS2 variations in age-related macular degeneration, polypoidal choroidal vasculopathy, and retinal angiomatous proliferation CFH and ARMS2 variations in age-related macular degeneration, polypoidal choroidal vasculopathy, and retinal angiomatous proliferation Investigative Ophthalmology and Visual Science, 51, 11, 5914-5919 , 51, 11, 5914-5919 Investigative Ophthalmology and Visual Science, 51, 11, 5914-5919 2010 英語 公開
H. Nakanishi; K. Yamashiro; R. Yamada; N. Gotoh; H. Hayashi; I. Nakata; M. Saito; T. Iida; A. Oishi; Y. Kurimoto; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura H. Nakanishi; K. Yamashiro; R. Yamada; N. Gotoh; H. Hayashi; I. Nakata; M. Saito; T. Iida; A. Oishi; Y. Kurimoto; K. Matsuo; K. Tajima; F. Matsuda; N. Yoshimura Joint effect of cigarette smoking and CFH and LOC387715/HTRA1 polymorphisms on polypoidal choroidal vasculopathy Joint effect of cigarette smoking and CFH and LOC387715/HTRA1 polymorphisms on polypoidal choroidal vasculopathy Investigative Ophthalmology and Visual Science, 51, 12, 6183-6187 , 51, 12, 6183-6187 Investigative Ophthalmology and Visual Science, 51, 12, 6183-6187 2010 英語 公開
Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, et al. Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, et al. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet. 2010 May 9. Nat Genet. 2010 May 9. 2010 英語 公開
Y. Okada; R. Yamada; A. Suzuki; Y. Kochi; K. Shimane; K. Myouzen; M. Kubo; Y. Nakamura; K. Yamamoto Y. Okada; R. Yamada; A. Suzuki; Y. Kochi; K. Shimane; K. Myouzen; M. Kubo; Y. Nakamura; K. Yamamoto Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1 Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1 Arthritis and Rheumatism, 60, 12, 3582-3590 , 60, 12, 3582-3590 Arthritis and Rheumatism, 60, 12, 3582-3590 2009/12 英語 公開
Y. Kochi; K. Myouzen; R. Yamada; A. Suzuki; T. Kurosaki; Y. Nakamura; K. Yamamoto Y. Kochi; K. Myouzen; R. Yamada; A. Suzuki; T. Kurosaki; Y. Nakamura; K. Yamamoto FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling Journal of Immunology, 183, 9, 5502-5510 , 183, 9, 5502-5510 Journal of Immunology, 183, 9, 5502-5510 2009/11/01 英語 公開
H. Nakanishi; R. Yamada; N. Gotoh; H. Hayashi; K. Yamashiro; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; T. Iida; K. Matsuo; K. Tajima; N. Yoshimura; F. Matsuda H. Nakanishi; R. Yamada; N. Gotoh; H. Hayashi; K. Yamashiro; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; T. Iida; K. Matsuo; K. Tajima; N. Yoshimura; F. Matsuda A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1 A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1 PLoS Genetics, 5, 9 , 5, 9 PLoS Genetics, 5, 9 2009/09 英語 公開
N. Gotoh; H. Nakanishi; H. Hayashi; R. Yamada; A. Otani; A. Tsujikawa; K. Yamashiro; H. Tamura; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura N. Gotoh; H. Nakanishi; H. Hayashi; R. Yamada; A. Otani; A. Tsujikawa; K. Yamashiro; H. Tamura; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura ARMS2 (LOC387715) Variants in Japanese Patients with Exudative Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy ARMS2 (LOC387715) Variants in Japanese Patients with Exudative Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy American Journal of Ophthalmology, 147, 6, 1037-1041 , 147, 6, 1037-1041 American Journal of Ophthalmology, 147, 6, 1037-1041 2009/06 英語 公開
R. Yamada; Y. Okada R. Yamada; Y. Okada An optimal dose-effect mode trend test for SNP genotype tables An optimal dose-effect mode trend test for SNP genotype tables Genetic Epidemiology, 33, 2, 114-127 , 33, 2, 114-127 Genetic Epidemiology, 33, 2, 114-127 2009/02 英語 公開
H. Nakanishi; R. Yamada; N. Gotoh; H. Hayashi; A. Otani; A. Tsujikawa; K. Yamashiro; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura H. Nakanishi; R. Yamada; N. Gotoh; H. Hayashi; A. Otani; A. Tsujikawa; K. Yamashiro; N. Shimada; K. Ohno-Matsui; M. Mochizuki; M. Saito; K. Saito; T. Iida; F. Matsuda; N. Yoshimura Absence of association between COL1A1 polymorphisms and high myopia in the Japanese population Absence of association between COL1A1 polymorphisms and high myopia in the Japanese population Investigative Ophthalmology and Visual Science, 50, 2, 544-550 , 50, 2, 544-550 Investigative Ophthalmology and Visual Science, 50, 2, 544-550 2009 英語 公開
K. Shimane; Y. Kochi; R. Yamada; Y. Okada; A. Suzuki; A. Miyatake; M. Kubo; Y. Nakamura; K. Yamamoto K. Shimane; Y. Kochi; R. Yamada; Y. Okada; A. Suzuki; A. Miyatake; M. Kubo; Y. Nakamura; K. Yamamoto A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population Annals of the Rheumatic Diseases, 68, 3, 377-383 , 68, 3, 377-383 Annals of the Rheumatic Diseases, 68, 3, 377-383 2009 英語 公開
M. Wada; H. Marusawa; R. Yamada; A. Nasu; Y. Osaki; M. Kudo; M. Nabeshima; Y. Fukuda; T. Chiba; F. Matsuda M. Wada; H. Marusawa; R. Yamada; A. Nasu; Y. Osaki; M. Kudo; M. Nabeshima; Y. Fukuda; T. Chiba; F. Matsuda Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients Journal of Viral Hepatitis, 16, 6, 388-396 , 16, 6, 388-396 Journal of Viral Hepatitis, 16, 6, 388-396 2009 英語 公開
Y. Kochi; A. Suzuki; R. Yamada; K. Yamamoto Y. Kochi; A. Suzuki; R. Yamada; K. Yamamoto Genetics of rheumatoid arthritis: Underlying evidence of ethnic differences Genetics of rheumatoid arthritis: Underlying evidence of ethnic differences Journal of Autoimmunity, 32, 3-4, 158-162 , 32, 3-4, 158-162 Journal of Autoimmunity, 32, 3-4, 158-162 2009 英語 公開
T. Sawada; T. Kanzaki; S. Hashimoto; A. Suzuki; R. Yamada; M. Odawara; K. Yamamoto T. Sawada; T. Kanzaki; S. Hashimoto; A. Suzuki; R. Yamada; M. Odawara; K. Yamamoto Citrullinated antigens as C1q-binding and monoclonal rheumatoid factor (mRF)-binding peptides in synovial fluids from rheumatoid arthritis patients Citrullinated antigens as C1q-binding and monoclonal rheumatoid factor (mRF)-binding peptides in synovial fluids from rheumatoid arthritis patients Clinical and Experimental Rheumatology, 27, 6, 989-992 , 27, 6, 989-992 Clinical and Experimental Rheumatology, 27, 6, 989-992 2009 英語 公開
A. Suzuki; R. Yamada; Y. Kochi; T. Sawada; Y. Okada; K. Matsuda; Y. Kamatani; M. Mori; K. Shimane; Y. Hirabayashi; A. Takahashi; T. Tsunoda; A. Miyatake; M. Kubo; N. Kamatani; Y. Nakamura; K. Yamamoto A. Suzuki; R. Yamada; Y. Kochi; T. Sawada; Y. Okada; K. Matsuda; Y. Kamatani; M. Mori; K. Shimane; Y. Hirabayashi; A. Takahashi; T. Tsunoda; A. Miyatake; M. Kubo; N. Kamatani; Y. Nakamura; K. Yamamoto Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population Nature Genetics, 40, 10, 1224-1229 , 40, 10, 1224-1229 Nature Genetics, 40, 10, 1224-1229 2008/10 英語 公開
N. Gotoh; R. Yamada; F. Matsuda; N. Yoshimura; T. Iida N. Gotoh; R. Yamada; F. Matsuda; N. Yoshimura; T. Iida Manganese Superoxide Dismutase Gene (SOD2) Polymorphism and Exudative Age-related Macular Degeneration in the Japanese Population Manganese Superoxide Dismutase Gene (SOD2) Polymorphism and Exudative Age-related Macular Degeneration in the Japanese Population American Journal of Ophthalmology, 146, 1, 146- , 146, 1, 146- American Journal of Ophthalmology, 146, 1, 146- 2008 英語 公開
R. Yamada R. Yamada Primer: SNP-associated studies and what they can teach us Primer: SNP-associated studies and what they can teach us Nature Clinical Practice Rheumatology, 4, 4, 210-217 , 4, 4, 210-217 Nature Clinical Practice Rheumatology, 4, 4, 210-217 2008 英語 公開
N. Gotoh; R. Yamada; H. Nakanishi; M. Saito; T. Iida; F. Matsuda; N. Yoshimura N. Gotoh; R. Yamada; H. Nakanishi; M. Saito; T. Iida; F. Matsuda; N. Yoshimura Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population Clinical and Experimental Ophthalmology, 36, 5, 437-442 , 36, 5, 437-442 Clinical and Experimental Ophthalmology, 36, 5, 437-442 2008 英語 公開
M. Nakayama-Hamada; A. Suzuki; H. Furukawa; R. Yamada; K. Yamamoto M. Nakayama-Hamada; A. Suzuki; H. Furukawa; R. Yamada; K. Yamamoto Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization Journal of Biochemistry, 144, 3, 393-398 , 144, 3, 393-398 Journal of Biochemistry, 144, 3, 393-398 2008 英語 公開
Y. Okada; M. Mori; R. Yamada; A. Suzuki; K. Kobayashi; M. Kubo; Y. Nakamura; K. Yamamoto Y. Okada; M. Mori; R. Yamada; A. Suzuki; K. Kobayashi; M. Kubo; Y. Nakamura; K. Yamamoto SLC22A4 polymorphism and rheumatoid arthritis susceptibility: A replication study in a Japanese population and a metaanalysis SLC22A4 polymorphism and rheumatoid arthritis susceptibility: A replication study in a Japanese population and a metaanalysis Journal of Rheumatology, 35, 9, 1723-1728 , 35, 9, 1723-1728 Journal of Rheumatology, 35, 9, 1723-1728 2008 英語 公開
K. Yamamoto; R. Yamada K. Yamamoto; R. Yamada Lessons from a genomewide association study of rheumatoid arthritis Lessons from a genomewide association study of rheumatoid arthritis New England Journal of Medicine, 357, 12, 1250-1251 , 357, 12, 1250-1251 New England Journal of Medicine, 357, 12, 1250-1251 2007 英語 公開
A. Suzuki; R. Yamada; K. Yamamoto A. Suzuki; R. Yamada; K. Yamamoto Citrullination by peptidylarginine deiminase in rheumatoid arthritis Citrullination by peptidylarginine deiminase in rheumatoid arthritis Annals of the New York Academy of Sciences, 1108, 323-339 , 1108, 323-339 Annals of the New York Academy of Sciences, 1108, 323-339 2007 英語 公開
R. Yamada; K. Yamamoto R. Yamada; K. Yamamoto Mechanisms of disease: Genetics of rheumatoid arthritis - Ethnic differences in disease-associated genes Mechanisms of disease: Genetics of rheumatoid arthritis - Ethnic differences in disease-associated genes Nature Clinical Practice Rheumatology, 3, 11, 644-650 , 3, 11, 644-650 Nature Clinical Practice Rheumatology, 3, 11, 644-650 2007 英語 公開
R. Yamada; F. Matsuda R. Yamada; F. Matsuda A novel method to express SNP-based genetic heterogeneity, Ψ, and its use to measure linkage disequilibrium for multiple SNPs, D<sub>g</sub>, and to estimate absolute maximum of haplotype frequency A novel method to express SNP-based genetic heterogeneity, Ψ, and its use to measure linkage disequilibrium for multiple SNPs, D<sub>g</sub>, and to estimate absolute maximum of haplotype frequency Genetic Epidemiology, 31, 7, 709-726 , 31, 7, 709-726 Genetic Epidemiology, 31, 7, 709-726 2007 英語 公開
K. Yamamoto; A. Suzuki; Y. Kochi; M. Mori; R. Yamada K. Yamamoto; A. Suzuki; Y. Kochi; M. Mori; R. Yamada Studies on the genes related to rheumatoid arthritis and the application of the results to clinical medicine Studies on the genes related to rheumatoid arthritis and the application of the results to clinical medicine Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 96, 9, 1845-1855 , 96, 9, 1845-1855 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 96, 9, 1845-1855 2007 英語 公開
Y. Okazaki; A. Suzuki; T. Sawada; M. Ohtake-Yamanaka; T. Inoue; T. Hasebe; R. Yamada; K. Yamamoto Y. Okazaki; A. Suzuki; T. Sawada; M. Ohtake-Yamanaka; T. Inoue; T. Hasebe; R. Yamada; K. Yamamoto Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis Biochemical and Biophysical Research Communications, 341, 1, 94-100 , 341, 1, 94-100 Biochemical and Biophysical Research Communications, 341, 1, 94-100 2006 英語 公開
N. Gotoh; R. Yamada; H. Hiratani; V. Renault; S. Kuroiwa; M. Monet; S. Toyoda; S. Chida; M. Mandai; A. Otani; N. Yoshimura; F. Matsuda N. Gotoh; R. Yamada; H. Hiratani; V. Renault; S. Kuroiwa; M. Monet; S. Toyoda; S. Chida; M. Mandai; A. Otani; N. Yoshimura; F. Matsuda No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese Human Genetics, 120, 1, 139-143 , 120, 1, 139-143 Human Genetics, 120, 1, 139-143 2006 英語 公開
Y. Takizawa; A. Suzuki; T. Sawada; M. Ohsaka; T. Inoue; R. Yamada; K. Yamamoto Y. Takizawa; A. Suzuki; T. Sawada; M. Ohsaka; T. Inoue; R. Yamada; K. Yamamoto Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids Annals of the Rheumatic Diseases, 65, 8, 1013-1020 , 65, 8, 1013-1020 Annals of the Rheumatic Diseases, 65, 8, 1013-1020 2006 英語 公開
X. Chang; R. Yamada; A. Suzuki; T. Sawada; S. Yoshino; S. Tokuhiro; K. Yamamoto X. Chang; R. Yamada; A. Suzuki; T. Sawada; S. Yoshino; S. Tokuhiro; K. Yamamoto Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis Rheumatology, 44, 1, 40-50 , 44, 1, 40-50 Rheumatology, 44, 1, 40-50 2005 英語 公開
S. Ohtsubo; A. Iida; K. Nitta; T. Tanaka; R. Yamada; Y. Ohnishi; S. Maeda; T. Tsunoda; T. Takei; W. Obara; F. Akiyama; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; W. Yumura; T. Ujiie; Y. Nagane; S. Miyano; Y. Suzuki; I. Narita; F. Gejyo; T. Fujioka; H. Nihei; Y. Nakamura S. Ohtsubo; A. Iida; K. Nitta; T. Tanaka; R. Yamada; Y. Ohnishi; S. Maeda; T. Tsunoda; T. Takei; W. Obara; F. Akiyama; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; W. Yumura; T. Ujiie; Y. Nagane; S. Miyano; Y. Suzuki; I. Narita; F. Gejyo; T. Fujioka; H. Nihei; Y. Nakamura Association of a single-nucleotide polymorphism in the immunoglobulin μ-binding protein 2 gene with immunoglobulin a nephropathy Association of a single-nucleotide polymorphism in the immunoglobulin μ-binding protein 2 gene with immunoglobulin a nephropathy Journal of Human Genetics, 50, 1, 30-35 , 50, 1, 30-35 Journal of Human Genetics, 50, 1, 30-35 2005 英語 公開
X. Chang; R. Yamada; T. Sawada; A. Suzuki; Y. Kochi; K. Yamamoto X. Chang; R. Yamada; T. Sawada; A. Suzuki; Y. Kochi; K. Yamamoto The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritis The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritis Rheumatology, 44, 3, 293-298 , 44, 3, 293-298 Rheumatology, 44, 3, 293-298 2005 英語 公開
R. Yamada; K. Ymamoto R. Yamada; K. Ymamoto Recent findings on genes associated with inflammatory disease Recent findings on genes associated with inflammatory disease Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 573, 1-2, 136-151 , 573, 1-2, 136-151 Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 573, 1-2, 136-151 2005 英語 公開
R. Yamada R. Yamada Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis Autoimmunity Reviews, 4, 4, 201-206 , 4, 4, 201-206 Autoimmunity Reviews, 4, 4, 201-206 2005 英語 公開
M. Nakayama-Hamada; A. Suzuki; K. Kubota; T. Takazawa; M. Ohsaka; R. Kawaida; M. Ono; A. Kasuya; H. Furukawa; R. Yamada; K. Yamamoto M. Nakayama-Hamada; A. Suzuki; K. Kubota; T. Takazawa; M. Ohsaka; R. Kawaida; M. Ono; A. Kasuya; H. Furukawa; R. Yamada; K. Yamamoto Comparison of enzymatic properties between hPADI2 and hPADI4 Comparison of enzymatic properties between hPADI2 and hPADI4 Biochemical and Biophysical Research Communications, 327, 1, 192-200 , 327, 1, 192-200 Biochemical and Biophysical Research Communications, 327, 1, 192-200 2005 英語 公開
A. Suzuki; R. Yamada; M. Ohtake-Yamanaka; Y. Okazaki; T. Sawada; K. Yamamoto A. Suzuki; R. Yamada; M. Ohtake-Yamanaka; Y. Okazaki; T. Sawada; K. Yamamoto Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis Biochemical and Biophysical Research Communications, 333, 2, 418-426 , 333, 2, 418-426 Biochemical and Biophysical Research Communications, 333, 2, 418-426 2005 英語 公開
R. Kawaida; R. Yamada; K. Kobayashi; S. Tokuhiro; A. Suzuki; Y. Kochi; X. Chang; A. Sekine; T. Tsunoda; T. Sawada; H. Furukawa; Y. Nakamura; K. Yamamoto R. Kawaida; R. Yamada; K. Kobayashi; S. Tokuhiro; A. Suzuki; Y. Kochi; X. Chang; A. Sekine; T. Tsunoda; T. Sawada; H. Furukawa; Y. Nakamura; K. Yamamoto CUL1, a component of E3 ubiquitin ligase, alters lymphocyte signal transduction with possible effect on rheumatoid arthritis CUL1, a component of E3 ubiquitin ligase, alters lymphocyte signal transduction with possible effect on rheumatoid arthritis Genes and Immunity, 6, 3, 194-202 , 6, 3, 194-202 Genes and Immunity, 6, 3, 194-202 2005 英語 公開
Y. Kochi; R. Yamada; A. Suzuki; J.B. Harley; S. Shirasawa; T. Sawada; S.-C. Bae; S. Tokuhiro; X. Chang; A. Sekine; A. Takahashi; T. Tsunoda; Y. Ohnishi; K.M. Kaufman; C.P. Kang; C. Kang; S. Otsubo; W. Yumura; A. Mimori; T. Koike; Y. Nakamura; T. Sasazuki; K. Yamamoto Y. Kochi; R. Yamada; A. Suzuki; J.B. Harley; S. Shirasawa; T. Sawada; S.-C. Bae; S. Tokuhiro; X. Chang; A. Sekine; A. Takahashi; T. Tsunoda; Y. Ohnishi; K.M. Kaufman; C.P. Kang; C. Kang; S. Otsubo; W. Yumura; A. Mimori; T. Koike; Y. Nakamura; T. Sasazuki; K. Yamamoto A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities Nature Genetics, 37, 5, 478-485 , 37, 5, 478-485 Nature Genetics, 37, 5, 478-485 2005 英語 公開
M. Mori; R. Yamada; K. Kobayashi; R. Kawaida; K. Yamamoto M. Mori; R. Yamada; K. Kobayashi; R. Kawaida; K. Yamamoto Ethnic differences in allele frequency of autoimmune-disease-associated SNPs Ethnic differences in allele frequency of autoimmune-disease-associated SNPs Journal of Human Genetics, 50, 5, 264-266 , 50, 5, 264-266 Journal of Human Genetics, 50, 5, 264-266 2005 英語 公開
Y. Takizawa; T. Sawada; A. Suzuki; R. Yamada; T. Inoue; K. Yamamoto Y. Takizawa; T. Sawada; A. Suzuki; R. Yamada; T. Inoue; K. Yamamoto Peptidylarginine deiminase 4 (PADI4) identified as a conformation-dependent autoantigen in rheumatoid arthritis Peptidylarginine deiminase 4 (PADI4) identified as a conformation-dependent autoantigen in rheumatoid arthritis Scandinavian Journal of Rheumatology, 34, 3, 212-215 , 34, 3, 212-215 Scandinavian Journal of Rheumatology, 34, 3, 212-215 2005 英語 公開
X. Chang; R. Yamada; A. Suzuki; Y. Kochi; T. Sawada; K. Yamamoto X. Chang; R. Yamada; A. Suzuki; Y. Kochi; T. Sawada; K. Yamamoto Citrullination of fibronectin in rheumatoid arthritis synovial tissue Citrullination of fibronectin in rheumatoid arthritis synovial tissue Rheumatology, 44, 11, 1374-1382 , 44, 11, 1374-1382 Rheumatology, 44, 11, 1374-1382 2005 英語 公開
K. Yamamoto; R. Yamada K. Yamamoto; R. Yamada Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis Journal of Autoimmunity, 25, SUPPL., 12-15 , 25, SUPPL., 12-15 Journal of Autoimmunity, 25, SUPPL., 12-15 2005 英語 公開
X. Chang; R. Yamada; K. Yamamoto X. Chang; R. Yamada; K. Yamamoto Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis. Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis. Arthritis research & therapy., 7, 2, R268-273 , 7, 2, R268-273 Arthritis research & therapy., 7, 2, R268-273 2005 英語 公開
R. Yamada; A. Suzuki; X. Chang; K. Yamamoto R. Yamada; A. Suzuki; X. Chang; K. Yamamoto Citrullinated proteins in rheumatoid arthritis Citrullinated proteins in rheumatoid arthritis Frontiers in Bioscience, 10, 1, 54-64 , 10, 1, 54-64 Frontiers in Bioscience, 10, 1, 54-64 2005 英語 公開
R. Yamada R. Yamada Susceptibility genes in rheumatoid arthritis: peptidylarginine deiminase (PADI) type 4 Susceptibility genes in rheumatoid arthritis: peptidylarginine deiminase (PADI) type 4 Nippon rinsho. Japanese journal of clinical medicine, 63 Suppl 1, 127-130 , 63 Suppl 1, 127-130 Nippon rinsho. Japanese journal of clinical medicine, 63 Suppl 1, 127-130 2005 英語 公開
K. Yamamoto; R. Yamada K. Yamamoto; R. Yamada Rheumatoid arthritis nd citrullinated antigens Rheumatoid arthritis nd citrullinated antigens [Zasshi] Journal. Nihon Naika Gakkai, 94, 5, 984-989 , 94, 5, 984-989 [Zasshi] Journal. Nihon Naika Gakkai, 94, 5, 984-989 2005 英語 公開
R. Yamada R. Yamada Identification of disease-susceptible genes of rheumatic diseases Identification of disease-susceptible genes of rheumatic diseases Nippon rinsho. Japanese journal of clinical medicine, 63 Suppl 5, 193-198 , 63 Suppl 5, 193-198 Nippon rinsho. Japanese journal of clinical medicine, 63 Suppl 5, 193-198 2005 英語 公開
T. Tsunoda; G.M. Lathrop; A. Sekine; R. Yamada; A. Takahashi; Y. Ohnishi; T. Tanaka; Y. Nakamura T. Tsunoda; G.M. Lathrop; A. Sekine; R. Yamada; A. Takahashi; Y. Ohnishi; T. Tanaka; Y. Nakamura Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome Human Molecular Genetics, 13, 15, 1623-1632 , 13, 15, 1623-1632 Human Molecular Genetics, 13, 15, 1623-1632 2004 英語 公開
R. Yamada; S. Tokuhiro; X. Chang; K. Yamamoto R. Yamada; S. Tokuhiro; X. Chang; K. Yamamoto SLC22A4 and RUNX1: Identification of RA susceptible genes SLC22A4 and RUNX1: Identification of RA susceptible genes Journal of Molecular Medicine, 82, 9, 558-564 , 82, 9, 558-564 Journal of Molecular Medicine, 82, 9, 558-564 2004 英語 公開
P.-C. Cha; R. Yamada; A. Sekine; Y. Nakamura; C.-L. Koh P.-C. Cha; R. Yamada; A. Sekine; Y. Nakamura; C.-L. Koh Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations Journal of Human Genetics, 49, 10, 558-572 , 49, 10, 558-572 Journal of Human Genetics, 49, 10, 558-572 2004 英語 公開
Y. Kochi; R. Yamada; K. Kobayashi; A. Takahashi; A. Suzuki; A. Sekine; A. Mabuchi; F. Akiyama; T. Tsunoda; Y. Nakamura; K. Yamamoto Y. Kochi; R. Yamada; K. Kobayashi; A. Takahashi; A. Suzuki; A. Sekine; A. Mabuchi; F. Akiyama; T. Tsunoda; Y. Nakamura; K. Yamamoto Analysis of Single-Nucleotide Polymorphisms in Japanese Rheumatoid Arthritis Patients Shows Additional Susceptibility Markers Besides the Classic Shared Epitope Susceptibility Sequences Analysis of Single-Nucleotide Polymorphisms in Japanese Rheumatoid Arthritis Patients Shows Additional Susceptibility Markers Besides the Classic Shared Epitope Susceptibility Sequences Arthritis and Rheumatism, 50, 1, 63-71 , 50, 1, 63-71 Arthritis and Rheumatism, 50, 1, 63-71 2004 英語 公開
A. Suzuki; R. Yamada; X. Chang; S. Tokuhiro; T. Sawada; M. Suzuki; M. Nagasaki; M. Nakayama-Hamada; R. Kawaida; M. Ono; M. Ohtsuki; H. Furukawa; S. Yoshino; M. Yukioka; S. Tohma; T. Matsubara; S. Wakitani; R. Teshima; Y. Nishioka; A. Sekine; A. Iida; A. Takahashi; T. Tsunoda; Y. Nakamura; K. Yamamoto A. Suzuki; R. Yamada; X. Chang; S. Tokuhiro; T. Sawada; M. Suzuki; M. Nagasaki; M. Nakayama-Hamada; R. Kawaida; M. Ono; M. Ohtsuki; H. Furukawa; S. Yoshino; M. Yukioka; S. Tohma; T. Matsubara; S. Wakitani; R. Teshima; Y. Nishioka; A. Sekine; A. Iida; A. Takahashi; T. Tsunoda; Y. Nakamura; K. Yamamoto Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis Nature Genetics, 34, 4, 395-402 , 34, 4, 395-402 Nature Genetics, 34, 4, 395-402 2003 英語 公開
S. Tokuhiro; R. Yamada; X. Chang; A. Suzuki; Y. Kochi; T. Sawada; M. Suzuki; M. Nagasaki; M. Ohtsuki; M. Ono; H. Furukawa; M. Nagashima; S. Yoshino; A. Mabuchi; A. Sekine; S. Saito; A. Takahashi; T. Tsunoda; Y. Nakamura; K. Yamamoto S. Tokuhiro; R. Yamada; X. Chang; A. Suzuki; Y. Kochi; T. Sawada; M. Suzuki; M. Nagasaki; M. Ohtsuki; M. Ono; H. Furukawa; M. Nagashima; S. Yoshino; A. Mabuchi; A. Sekine; S. Saito; A. Takahashi; T. Tsunoda; Y. Nakamura; K. Yamamoto An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis Nature Genetics, 35, 4, 341-348 , 35, 4, 341-348 Nature Genetics, 35, 4, 341-348 2003 英語 公開
R. Yamada; A. Suzuki; X. Chang; K. Yamamoto R. Yamada; A. Suzuki; X. Chang; K. Yamamoto Peptidylarginine deiminase type 4: Identification of a rheumatoid arthritis-susceptible gene Peptidylarginine deiminase type 4: Identification of a rheumatoid arthritis-susceptible gene Trends in Molecular Medicine, 9, 11, 503-508 , 9, 11, 503-508 Trends in Molecular Medicine, 9, 11, 503-508 2003 英語 公開
W. Obara; A. Iida; Y. Suzuki; T. Tanaka; F. Akiyama; S. Maeda; Y. Ohnishi; R. Yamada; T. Tsunoda; T. Takei; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; W. Yumura; T. Ujiie; Y. Nagane; K. Nitta; S. Miyano; I. Narita; F. Gejyo; H. Nihei; T. Fujioka; Y. Nakamura W. Obara; A. Iida; Y. Suzuki; T. Tanaka; F. Akiyama; S. Maeda; Y. Ohnishi; R. Yamada; T. Tsunoda; T. Takei; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; W. Yumura; T. Ujiie; Y. Nagane; K. Nitta; S. Miyano; I. Narita; F. Gejyo; H. Nihei; T. Fujioka; Y. Nakamura Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients Journal of Human Genetics, 48, 6, 293-299 , 48, 6, 293-299 Journal of Human Genetics, 48, 6, 293-299 2003 英語 公開
T. Ikeda; A. Mabuchi; A. Fukuda; A. Kawakami; R. Yamada; S. Yamamoto; K. Miyoshi; N. Haga; H. Hiraoka; Y. Takatori; H. Kawaguchi; K. Nakamura; S. Ikegawa T. Ikeda; A. Mabuchi; A. Fukuda; A. Kawakami; R. Yamada; S. Yamamoto; K. Miyoshi; N. Haga; H. Hiraoka; Y. Takatori; H. Kawaguchi; K. Nakamura; S. Ikegawa Association analysis of single nucleotide polymorphisms in cartilage-specific collagen genes with knee and hip osteoarthritis in the Japanese population Association analysis of single nucleotide polymorphisms in cartilage-specific collagen genes with knee and hip osteoarthritis in the Japanese population Journal of Bone and Mineral Research, 17, 7, 1290-1296 , 17, 7, 1290-1296 Journal of Bone and Mineral Research, 17, 7, 1290-1296 2002 英語 公開
T. Takei; A. Iida; K. Nitta; T. Tanaka; Y. Ohnishi; R. Yamada; S. Maeda; T. Tsunoda; S. Takeoka; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; Y. Suzuki; T. Fujioka; T. Ujiie; Y. Nagane; S. Miyano; I. Narita; F. Gejyo; H. Nihei; Y. Nakamura T. Takei; A. Iida; K. Nitta; T. Tanaka; Y. Ohnishi; R. Yamada; S. Maeda; T. Tsunoda; S. Takeoka; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; Y. Suzuki; T. Fujioka; T. Ujiie; Y. Nagane; S. Miyano; I. Narita; F. Gejyo; H. Nihei; Y. Nakamura Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin a nephropathy Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin a nephropathy American Journal of Human Genetics, 70, 3, 781-786 , 70, 3, 781-786 American Journal of Human Genetics, 70, 3, 781-786 2002 英語 公開
F. Akiyama; T. Tanaka; R. Yamada; Y. Ohnishi; T. Tsunoda; S. Maeda; T. Takei; W. Obara; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; K. Nitta; W. Yumura; H. Nihei; T. Ujiie; Y. Nagane; S. Miyano; Y. Suzuki; T. Fujioka; I. Narita; F. Gejyo; Y. Nakamura F. Akiyama; T. Tanaka; R. Yamada; Y. Ohnishi; T. Tsunoda; S. Maeda; T. Takei; W. Obara; K. Ito; K. Honda; K. Uchida; K. Tsuchiya; K. Nitta; W. Yumura; H. Nihei; T. Ujiie; Y. Nagane; S. Miyano; Y. Suzuki; T. Fujioka; I. Narita; F. Gejyo; Y. Nakamura Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy Journal of Human Genetics, 47, 10, 532-538 , 47, 10, 532-538 Journal of Human Genetics, 47, 10, 532-538 2002 英語 公開
K. Ozaki; Y. Ohnishi; A. Iida; A. Sekine; R. Yamada; T. Tsunoda; H. Sato; H. Sato; M. Hori; Y. Nakamura; T. Tanaka K. Ozaki; Y. Ohnishi; A. Iida; A. Sekine; R. Yamada; T. Tsunoda; H. Sato; H. Sato; M. Hori; Y. Nakamura; T. Tanaka Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction Nature Genetics, 32, 4, 650-654 , 32, 4, 650-654 Nature Genetics, 32, 4, 650-654 2002 英語 公開
H. Haga; R. Yamada; Y. Ohnishi; Y. Nakamura; T. Tanaka H. Haga; R. Yamada; Y. Ohnishi; Y. Nakamura; T. Tanaka Gene-based SNP discovery as part of the Japanese Millennium Genome Project: Identification of 190 562 genetic variations in the human genome Gene-based SNP discovery as part of the Japanese Millennium Genome Project: Identification of 190 562 genetic variations in the human genome Journal of Human Genetics, 47, 11, 605-610 , 47, 11, 605-610 Journal of Human Genetics, 47, 11, 605-610 2002 英語 公開
Y. Ohnishi; T. Tanaka; K. Ozaki; R. Yamada; H. Suzuki; Y. Nakamura Y. Ohnishi; T. Tanaka; K. Ozaki; R. Yamada; H. Suzuki; Y. Nakamura A high-throughput SNP typing system for genome-wide association studies A high-throughput SNP typing system for genome-wide association studies Journal of Human Genetics, 46, 8, 471-477 , 46, 8, 471-477 Journal of Human Genetics, 46, 8, 471-477 2001 英語 公開
R. Yamada; T. Tanaka; M. Unoki; T. Nagai; T. Sawada; Y. Ohnishi; T. Tsunoda; M. Yukioka; A. Maeda; K. Suzuki; H. Tateishi; T. Ochi; Y. Nakamura; K. Yamamoto R. Yamada; T. Tanaka; M. Unoki; T. Nagai; T. Sawada; Y. Ohnishi; T. Tsunoda; M. Yukioka; A. Maeda; K. Suzuki; H. Tateishi; T. Ochi; Y. Nakamura; K. Yamamoto Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to t Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to t American Journal of Human Genetics, 68, 3, 674-685 , 68, 3, 674-685 American Journal of Human Genetics, 68, 3, 674-685 2001 英語 公開
R. Yamada; T. Tanaka; Y. Ohnishi; K. Suematsu; M. Minami; T. Seki; M. Yukioka; A. Maeda; N. Murata; O. Saiki; R. Teshima; O. Kudo; K. Ishikawa; A. Ueyosi; H. Tateishi; M. Inaba; H. Goto; Y. Nishizawa; S. Tohma; T. Ochi; K. Yamamoto; Y. Nakamura R. Yamada; T. Tanaka; Y. Ohnishi; K. Suematsu; M. Minami; T. Seki; M. Yukioka; A. Maeda; N. Murata; O. Saiki; R. Teshima; O. Kudo; K. Ishikawa; A. Ueyosi; H. Tateishi; M. Inaba; H. Goto; Y. Nishizawa; S. Tohma; T. Ochi; K. Yamamoto; Y. Nakamura Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population Human Genetics, 106, 3, 293-297 , 106, 3, 293-297 Human Genetics, 106, 3, 293-297 2000 英語 公開
Y. Ohnishi; T. Tanaka; R. Yamada; K. Suematsu; M. Minami; K. Fujii; N. Hoki; K. Kodama; S. Nagata; T. Hayashi; N. Kinoshita; H. Sato; H. Sato; T. Kuzuya; H. Takeda; M. Hori; Y. Nakamura Y. Ohnishi; T. Tanaka; R. Yamada; K. Suematsu; M. Minami; K. Fujii; N. Hoki; K. Kodama; S. Nagata; T. Hayashi; N. Kinoshita; H. Sato; H. Sato; T. Kuzuya; H. Takeda; M. Hori; Y. Nakamura Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population Human Genetics, 106, 3, 288-292 , 106, 3, 288-292 Human Genetics, 106, 3, 288-292 2000 英語 公開

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タイトル言語:
Misc
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
R. Yamada R. Yamada How to measure genetic heterogeneity How to measure genetic heterogeneity Journal of Physics: Conference Series, 197 , 197 Journal of Physics: Conference Series, 197 2009 英語 公開
T. Tsunoda; R. Yamada; T. Tanaka; Y. Ohnishi; N. Kamatani T. Tsunoda; R. Yamada; T. Tanaka; Y. Ohnishi; N. Kamatani Environmental factor dependent maximum likelihood method for association study targeted to personalized medicine. Environmental factor dependent maximum likelihood method for association study targeted to personalized medicine. Genome informatics series : proceedings of the . Workshop on Genome Informatics. Workshop on Genome Informatics, 11, 96-105 , 11, 96-105 Genome informatics series : proceedings of the . Workshop on Genome Informatics. Workshop on Genome Informatics, 11, 96-105 2000 英語 公開
タイトル言語:
書籍等出版物
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 出版社 出版社(日本語) 出版社(英語) 出版年月 記述言語 担当区分 公開
山田 亮 山田 亮 遺伝統計学の基礎 遺伝統計学の基礎 オーム社 オーム社 2010/09/04 日本語 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
H23 基盤研究(A)加齢黄斑変性 分担
H23 厚生労働科学研究費補助金(創薬基盤推進研究事業) 分担 ゲノム網羅的関連解析の大規模メタ解析を基盤としたcommon diseaseのテーラーメード医療実用化に関する研究班
H23 厚生労働科学研究費補助金(難治性疾患克服研究事業) 分担 自己免疫疾患に関する調査研究班
基盤研究(C) 代表 複数の臨床診断項目が定義する疾患形質の遺伝疫学解析手法に関する研究 2011〜2013
特別研究員奨励費 代表 集団遺伝学的アプローチによる疾患関連遺伝子の同定 2013〜2015
特別研究員奨励費 代表 集団遺伝学的アプローチによる疾患関連遺伝子の同定 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(C) 代表 個別化する意思決定を支援する医療情報提供手法の開発 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(C) 代表 個別化する意思決定を支援する医療情報提供手法の開発 (平成27年度分) 2015/04/01〜2016/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) 分担 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(C) 代表 個別化する意思決定を支援する医療情報提供手法の開発 (平成28年度分) 2016/04/01〜2017/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) 分担 (平成28年度分) 2016/04/01〜2017/03/31
基盤研究(C) 代表 多層オミクスデータ統合解析のための情報幾何的ベイズ推定法の開発 (平成29年度分) 2017/04/01〜2018/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) 分担 (平成29年度分) 2017/04/01〜2018/03/31
難治性疾患等政策研究事業(難治性疾患政策研究事業) 分担 (平成30年度分) 2018/04/01〜2019/03/31
基盤研究(C) 代表 多層オミクスデータ統合解析のための情報幾何的ベイズ推定法の開発 (平成30年度分) 2018/04/01〜2019/03/31

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担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
ゲノム疫学のためのインフォマティクスI 前期不定 医学研究科 2012/04〜2013/03
ゲノム疫学のためのインフォマティクスII 後期不定 医学研究科 2012/04〜2013/03
統計遺伝学 I 前期不定 医学研究科 2013/04〜2014/03
統計遺伝学 II 後期不定 医学研究科 2013/04〜2014/03
オミックス統計学入門 I Introductory Omics-Statistics I 前期不定 医学研究科 2014/04〜2015/03
オミックス統計学入門 II Introductory Omics-Statistics II 後期不定 医学研究科 2014/04〜2015/03
医学のための数学基礎 Basic Mathematics for Medicine with Free Application R 前期集中 全学共通科目 2015/04〜2016/03
多細胞体ネットワーク特論 Advanced Course in Multicellular Network 前期集中 生命科学研究科 2015/04〜2016/03
ゲノム・オミックス統計解析コース(実習) Genome and Omics Statistical Analysis (Practice) 通年不定 医学研究科 2015/04〜2016/03
ゲノム・オミックス統計解析(演習) Genome and Omics Statistical Analysis (Seminar) 通年不定 医学研究科 2015/04〜2016/03
統計遺伝学基礎 II Introductory Genetics-Statistics II 後期不定 医学研究科 2015/04〜2016/03
統計遺伝学基礎 I Introductory Genetics-Statistics I 前期不定 医学研究科 2015/04〜2016/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2016/04〜2017/03
ゲノム・オミックス統計解析(実習) Genome and Omics Statistical Analysis (Practice) 通年不定 医学研究科 2016/04〜2017/03
ゲノム・オミックス統計解析(演習) Genome and Omics Statistical Analysis (Seminar) 通年不定 医学研究科 2016/04〜2017/03
統計遺伝学 II Statistical Genetics II 後期不定 医学研究科 2016/04〜2017/03
統計遺伝学 I Statistical Genetics I 前期不定 医学研究科 2016/04〜2017/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2017/04〜2018/03
ゲノム・オミックス統計解析(実習) Genome and Omics Statistical Analysis (Practice) 通年不定 医学研究科 2017/04〜2018/03
ゲノム・オミックス統計解析(演習) Genome and Omics Statistical Analysis (Seminar) 通年不定 医学研究科 2017/04〜2018/03
統計遺伝学基礎 II Introductory Genetics-Statistics II 後期不定 医学研究科 2017/04〜2018/03
統計遺伝学基礎 I Introductory Genetics-Statistics I 前期不定 医学研究科 2017/04〜2018/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2018/04〜2019/03
統計的学習II Statistical Learning II 後期 全学共通科目 2018/04〜2019/03
統計的学習 II Statistical Learning II 後期 医学研究科 2018/04〜2019/03
統計的学習 I Statistical Learning I 前期 医学研究科 2018/04〜2019/03
統計的学習I Statistical Learning I 前期 全学共通科目 2018/04〜2019/03
ゲノム・オミックス統計解析(実習) Genome and Omics Statistical Analysis (Practice) 通年不定 医学研究科 2018/04〜2019/03
ゲノム・オミックス統計解析(演習) Genome and Omics Statistical Analysis (Seminar) 通年不定 医学研究科 2018/04〜2019/03
統計遺伝学II Statistical Genetics II 後期 全学共通科目 2018/04〜2019/03
統計遺伝学 II Statistical Genetics II 後期 医学研究科 2018/04〜2019/03
統計遺伝学 I Statistical Genetics I 前期 医学研究科 2018/04〜2019/03
統計遺伝学I Statistical Genetics I 前期 全学共通科目 2018/04〜2019/03
ゲノム・オミックス解析手法I Genome/Omics Analysis Method I 前期 全学共通科目 2018/04〜2019/03
ゲノム・オミックス解析手法II Genome/Omics Analysis Method II 後期 全学共通科目 2018/04〜2019/03
ゲノム・オミックス解析手法 II Methods of Genome and Omics Analysis II 後期 医学研究科 2018/04〜2019/03
ゲノム・オミックス解析手法 I Methods of Genome and Omics Analysis I 前期 医学研究科 2018/04〜2019/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2019/04〜2020/03
統計的学習II Statistical Learning II 後期 全学共通科目 2019/04〜2020/03
統計的学習 II Statistical Learning II 後期 医学研究科 2019/04〜2020/03
統計的学習 I Statistical Learning I 前期 医学研究科 2019/04〜2020/03
統計的学習I Statistical Learning I 前期 全学共通科目 2019/04〜2020/03
ゲノム・オミックス統計解析(修士実習) Genome and Omics Statistical Analysis (Practice for Master Program) 通年不定 医学研究科 2019/04〜2020/03
ゲノム・オミックス統計解析(修士演習) Genome and Omics Statistical Analysis (Seminar for Master Program) 通年不定 医学研究科 2019/04〜2020/03
ゲノム・オミックス統計解析(実習) Genome and Omics Statistical Analysis (Practice) 通年不定 医学研究科 2019/04〜2020/03
ゲノム・オミックス統計解析(演習) Genome and Omics Statistical Analysis (Seminar) 通年不定 医学研究科 2019/04〜2020/03
統計遺伝学II Statistical Genetics II 後期 全学共通科目 2019/04〜2020/03
統計遺伝学 II Statistical Genetics II 後期 医学研究科 2019/04〜2020/03
統計遺伝学 I Statistical Genetics I 前期 医学研究科 2019/04〜2020/03
統計遺伝学I Statistical Genetics I 前期 全学共通科目 2019/04〜2020/03
ゲノム・オミックス解析手法I Genome/Omics Analysis Method I 前期 全学共通科目 2019/04〜2020/03
ゲノム・オミックス解析手法 II Methods of Genome and Omics Analysis II 後期 医学研究科 2019/04〜2020/03
ゲノム・オミックス解析手法 I Methods of Genome and Omics Analysis I 前期 医学研究科 2019/04〜2020/03

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学外非常勤講師
講義名(日本語) 講義名(英語) 開講期 学校名 学部/研究科名 期間
ゲノムサイエンス概論 久留米大学 2019/04/01〜2020/03/31
ゲノム統計学大意 久留米大学 2019/04/01〜2020/03/31
サークルの顧問
サークル名(日本語) サークル名(英語) 期間
MIKU Medicoinformatics Kyoto University (MIKU) 2010/11/19〜
医学部バドミントン部 2018/04/01〜
全学運営(役職等)
役職名 期間
情報環境機構教育用コンピュータシステム運用委員
全学共通教育システム委員 
KUINS利用負担金検討委員会
国際教育委員会留学生受入専門委員会アムジェン・スカラーズ・プログラム小委員会 委員 2016/04/01〜2018/03/31
スーパーグローバルコース実施運営協議会企画運営幹事会 委員 2016/04/01〜2017/03/31
スーパーグローバルコース実施運営協議会 委員 2015/12/01〜2018/03/31
スーパーグローバルコース企画運営幹事会 委員 2016/04/01〜2018/03/31
情報セキュリティ委員会幹事会
国際高等教育院 企画評価専門委員会 数学部会 委員 2015/05/01〜2019/03/31
スーパーグローバルコース企画運営幹事会 委員 2016/04/01〜2019/03/31
スーパーグローバルコース実施運営協議会 委員 2015/12/01〜2019/03/31
臨床研究審査委員会 副委員長 2018/04/01〜2019/03/31

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部局運営(役職等)
役職名 期間
研究倫理委員会委員 
論文調査委員選定委員
医学図書館運営委員 
医学図書館図書連絡委員 2013/04/01〜2019/03/31
医学広報委員会 2013/10/01〜2017/09/30
医学研究科・医学部及び医学部附属病院医の倫理委員会 2013/04/01〜2019/03/31
医学研究科学術情報システム・情報セキュリティ委員会 2014/04/01〜2020/03/31
管理体制委員会 2012/10/01〜2014/09/30
附属ゲノム医学センター運営委員会 2010/04/01〜
学務委員会 2016/04/01〜2018/09/30
京都大学特定認定再生医療等委員会 2017/04/01〜2019/03/31
副研究科長 2017/10/01〜2018/09/30
専攻長会議・関係学系長会議
国際交流委員会 2017/10/01〜2018/09/30
医の倫理委員会 2013/04/01〜2019/03/31
大倉辰三郎・喜美奨学金選考小委員会 2017/10/01〜2018/09/30
医学研究科教員人事活性化委員会 2017/10/01〜
医学教育・国際化推進センター運営委員会
京都大学臨床研究審査委員会 2018/04/01〜2019/03/31

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