永安 一樹

最終更新日時: 2018/06/29 15:48:00

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氏名(漢字/フリガナ/アルファベット表記)
永安 一樹/ナガヤス カズキ/Kazuki Nagayasu
所属部署・職名(部局/所属/講座等/職名)
薬学研究科/薬学専攻病態機能解析学講座/助教
学部兼担
部局 所属 講座等 職名
薬学部
連絡先住所
種別 住所(日本語) 住所(英語)
職場 京都市左京区吉田下阿達町46-29 46-29 Yoshidashimoadachicho, Sakyo, Kyoto
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
修士(薬学) 京都大学
博士(薬学) 京都大学
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Asaoka N, Nishitani N, Kinoshita H, Kawai H, Shibui N, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nishitani N, Kinoshita H, Kawai H, Shibui N, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nishitani N, Kinoshita H, Kawai H, Shibui N, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABA<sub>B</sub> receptor-mediated inhibition of L-type calcium channels. Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABA<sub>B</sub> receptor-mediated inhibition of L-type calcium channels. Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABA<sub>B</sub> receptor-mediated inhibition of L-type calcium channels. Scientific reports, 7, 1, 13609 Scientific reports, 7, 1, 13609 Scientific reports, 7, 1, 13609 2017/10 公開
Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue KI, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue KI, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue KI, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates. High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates. High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates. Neuron, 94, 6, 1085-1100.e6 Neuron, 94, 6, 1085-1100.e6 Neuron, 94, 6, 1085-1100.e6 2017/06 公開
Shirakawa H, Katsumoto R, Iida S, Miyake T, Higuchi T, Nagashima T, Nagayasu K, Nakagawa T, Kaneko S Shirakawa H, Katsumoto R, Iida S, Miyake T, Higuchi T, Nagashima T, Nagayasu K, Nakagawa T, Kaneko S Shirakawa H, Katsumoto R, Iida S, Miyake T, Higuchi T, Nagashima T, Nagayasu K, Nakagawa T, Kaneko S Sphingosine-1-phosphate induces Ca<sup>2+</sup> signaling and CXCL1 release via TRPC6 channel in astrocytes. Sphingosine-1-phosphate induces Ca<sup>2+</sup> signaling and CXCL1 release via TRPC6 channel in astrocytes. Sphingosine-1-phosphate induces Ca<sup>2+</sup> signaling and CXCL1 release via TRPC6 channel in astrocytes. Glia, 65, 6, 1005-1016 Glia, 65, 6, 1005-1016 Glia, 65, 6, 1005-1016 2017/06 公開
Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Schizophrenia research, 181, 75-82 Schizophrenia research, 181, 75-82 Schizophrenia research, 181, 75-82 2017/03 公開
Sukeishi A, Isami K, Hiyama H, Imai S, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Sukeishi A, Isami K, Hiyama H, Imai S, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Sukeishi A, Isami K, Hiyama H, Imai S, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S [EXPRESS] Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages. [EXPRESS] Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages. [EXPRESS] Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages. Molecular pain, 13, 1744806917743680 Molecular pain, 13, 1744806917743680 Molecular pain, 13, 1744806917743680 2017/01 公開
Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide. Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide. Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide. Frontiers in physiology, 8, 877 Frontiers in physiology, 8, 877 Frontiers in physiology, 8, 877 2017 公開
Miyake T, Nakamura S, Meng Z, Hamano S, Inoue K, Numata T, Takahashi N, Nagayasu K, Shirakawa H, Mori Y, Nakagawa T, Kaneko S Miyake T, Nakamura S, Meng Z, Hamano S, Inoue K, Numata T, Takahashi N, Nagayasu K, Shirakawa H, Mori Y, Nakagawa T, Kaneko S Miyake T, Nakamura S, Meng Z, Hamano S, Inoue K, Numata T, Takahashi N, Nagayasu K, Shirakawa H, Mori Y, Nakagawa T, Kaneko S Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin. Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin. Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin. Frontiers in physiology, 8, 878 Frontiers in physiology, 8, 878 Frontiers in physiology, 8, 878 2017 公開
Nagayasu K Nagayasu K Nagayasu K Elucidation of the Role of Dorsal Raphe Serotonergic Neurons in Mood Regulation Using Pharmacological and Viral Vector-based Approaches. Elucidation of the Role of Dorsal Raphe Serotonergic Neurons in Mood Regulation Using Pharmacological and Viral Vector-based Approaches. Elucidation of the Role of Dorsal Raphe Serotonergic Neurons in Mood Regulation Using Pharmacological and Viral Vector-based Approaches. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 137, 3, 341-346 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 137, 3, 341-346 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 137, 3, 341-346 2017 公開
Nagayasu K, Kaneko S Nagayasu K, Kaneko S Nagayasu K, Kaneko S Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation. Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation. Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 149, 1, 44-47 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 149, 1, 44-47 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 149, 1, 44-47 2017 公開
Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction. Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction. Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction. Behavioural brain research, 314, 77-86 Behavioural brain research, 314, 77-86 Behavioural brain research, 314, 77-86 2016/11 公開
Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawashima H, Yamamori H, Fujimoto M, Ohi K, Umeda-Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawashima H, Yamamori H, Fujimoto M, Ohi K, Umeda-Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawashima H, Yamamori H, Fujimoto M, Ohi K, Umeda-Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder. Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder. Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder. Journal of human genetics, 61, 3, 199-206 Journal of human genetics, 61, 3, 199-206 Journal of human genetics, 61, 3, 199-206 2016/03 公開
Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons. A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons. A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons. The Journal of toxicological sciences, 41, 6, 813-816 The Journal of toxicological sciences, 41, 6, 813-816 The Journal of toxicological sciences, 41, 6, 813-816 2016 公開
Matsumura K, Nakazawa T, Nagayasu K, Gotoda-Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H Matsumura K, Nakazawa T, Nagayasu K, Gotoda-Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H Matsumura K, Nakazawa T, Nagayasu K, Gotoda-Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ. De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ. De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ. Journal of molecular psychiatry, 4, 1 Journal of molecular psychiatry, 4, 1 Journal of molecular psychiatry, 4, 1 2016 公開
Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus. Neuropharmacology, 95, 261-268 Neuropharmacology, 95, 261-268 Neuropharmacology, 95, 261-268 2015/08 公開
Ikeda K, Tomimoto S, Tsuchiya S, Hamagami KI, Shintani N, Sugimoto Y, Ichikawa A, Kasai A, Nakazawa T, Nagayasu K, Hayata-Takano A, Baba A, Hashimoto H Ikeda K, Tomimoto S, Tsuchiya S, Hamagami KI, Shintani N, Sugimoto Y, Ichikawa A, Kasai A, Nakazawa T, Nagayasu K, Hayata-Takano A, Baba A, Hashimoto H Ikeda K, Tomimoto S, Tsuchiya S, Hamagami KI, Shintani N, Sugimoto Y, Ichikawa A, Kasai A, Nakazawa T, Nagayasu K, Hayata-Takano A, Baba A, Hashimoto H Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice. Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice. Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice. Biochemistry and biophysics reports, 2, 179-183 Biochemistry and biophysics reports, 2, 179-183 Biochemistry and biophysics reports, 2, 179-183 2015/07 公開
Higashi S, Katagi K, Shintani N, Ikeda K, Sugimoto Y, Tsuchiya S, Inoue N, Tanaka S, Koumoto M, Kasai A, Nakazawa T, Hayata-Takano A, Hamagami K, Tomimoto S, Yoshida T, Ohkubo T, Nagayasu K, Ago Y, Onaka Y, Hashimoto R, Ichikawa A, Baba A, Hashimoto H Higashi S, Katagi K, Shintani N, Ikeda K, Sugimoto Y, Tsuchiya S, Inoue N, Tanaka S, Koumoto M, Kasai A, Nakazawa T, Hayata-Takano A, Hamagami K, Tomimoto S, Yoshida T, Ohkubo T, Nagayasu K, Ago Y, Onaka Y, Hashimoto R, Ichikawa A, Baba A, Hashimoto H Higashi S, Katagi K, Shintani N, Ikeda K, Sugimoto Y, Tsuchiya S, Inoue N, Tanaka S, Koumoto M, Kasai A, Nakazawa T, Hayata-Takano A, Hamagami K, Tomimoto S, Yoshida T, Ohkubo T, Nagayasu K, Ago Y, Onaka Y, Hashimoto R, Ichikawa A, Baba A, Hashimoto H p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice. p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice. p13 overexpression in pancreatic β-cells ameliorates type 2 diabetes in high-fat-fed mice. Biochemical and biophysical research communications, 461, 4, 612-617 Biochemical and biophysical research communications, 461, 4, 612-617 Biochemical and biophysical research communications, 461, 4, 612-617 2015/06 公開
Imoto Y, Kira T, Sukeno M, Nishitani N, Nagayasu K, Nakagawa T, Kaneko S, Kobayashi K, Segi-Nishida E Imoto Y, Kira T, Sukeno M, Nishitani N, Nagayasu K, Nakagawa T, Kaneko S, Kobayashi K, Segi-Nishida E Imoto Y, Kira T, Sukeno M, Nishitani N, Nagayasu K, Nakagawa T, Kaneko S, Kobayashi K, Segi-Nishida E Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Molecular brain, 8, 1 Molecular brain, 8, 1 Molecular brain, 8, 1 2015/05 公開
Onaka Y, Shintani N, Nakazawa T, Haba R, Ago Y, Wang H, Kanoh T, Hayata-Takano A, Hirai H, Nagata KY, Nakamura M, Hashimoto R, Matsuda T, Waschek JA, Kasai A, Nagayasu K, Baba A, Hashimoto H Onaka Y, Shintani N, Nakazawa T, Haba R, Ago Y, Wang H, Kanoh T, Hayata-Takano A, Hirai H, Nagata KY, Nakamura M, Hashimoto R, Matsuda T, Waschek JA, Kasai A, Nagayasu K, Baba A, Hashimoto H Onaka Y, Shintani N, Nakazawa T, Haba R, Ago Y, Wang H, Kanoh T, Hayata-Takano A, Hirai H, Nagata KY, Nakamura M, Hashimoto R, Matsuda T, Waschek JA, Kasai A, Nagayasu K, Baba A, Hashimoto H CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice. CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice. CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice. Behavioural brain research, 284, 131-137 Behavioural brain research, 284, 131-137 Behavioural brain research, 284, 131-137 2015/05 公開
Nakagawa T, Nagayasu K, Kaneko S Nakagawa T, Nagayasu K, Kaneko S Nakagawa T, Nagayasu K, Kaneko S [Utility of organotypic raphe slice cultures to investigate the effects of psychotropic drugs on the function of serotoninergic neurons]. [Utility of organotypic raphe slice cultures to investigate the effects of psychotropic drugs on the function of serotoninergic neurons]. [Utility of organotypic raphe slice cultures to investigate the effects of psychotropic drugs on the function of serotoninergic neurons]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 35, 2, 39-44 Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 35, 2, 39-44 Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 35, 2, 39-44 2015/04 公開
Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures. Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures. Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures. Neuroscience letters, 593, 72-77 Neuroscience letters, 593, 72-77 Neuroscience letters, 593, 72-77 2015/04 公開
Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H Simultaneous neuron- and astrocyte-specific fluorescent marking. Simultaneous neuron- and astrocyte-specific fluorescent marking. Simultaneous neuron- and astrocyte-specific fluorescent marking. Biochemical and biophysical research communications, 459, 1, 81-86 Biochemical and biophysical research communications, 459, 1, 81-86 Biochemical and biophysical research communications, 459, 1, 81-86 2015/03 公開
Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, Matsuda T, Baba A, Hashimoto H Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, Matsuda T, Baba A, Hashimoto H Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, Matsuda T, Baba A, Hashimoto H Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro. Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro. Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro. Journal of neurochemistry, 132, 4, 418-428 Journal of neurochemistry, 132, 4, 418-428 Journal of neurochemistry, 132, 4, 418-428 2015/02 公開
Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. PloS one, 10, 3 PloS one, 10, 3 PloS one, 10, 3 2015 公開
Ogata K, Shintani N, Hayata-Takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudry D, Vaudry H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, Matsuda T, Baba A, Hashimoto H Ogata K, Shintani N, Hayata-Takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudry D, Vaudry H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, Matsuda T, Baba A, Hashimoto H Ogata K, Shintani N, Hayata-Takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudry D, Vaudry H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, Matsuda T, Baba A, Hashimoto H PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. PACAP enhances axon outgrowth in cultured hippocampal neurons to a comparable extent as BDNF. PloS one, 10, 3 PloS one, 10, 3 PloS one, 10, 3 2015 公開
Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H Behavioral characterization of mice overexpressing human dysbindin-1. Behavioral characterization of mice overexpressing human dysbindin-1. Behavioral characterization of mice overexpressing human dysbindin-1. Molecular brain, 7, 1 Molecular brain, 7, 1 Molecular brain, 7, 1 2014/10 公開
Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex. Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex. Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 17, 8, 1321-1326 The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 17, 8, 1321-1326 The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 17, 8, 1321-1326 2014/08 公開
Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Hashimoto R, Nagayasu K, Nakazawa T, Hashimoto H, Baba A Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Hashimoto R, Nagayasu K, Nakazawa T, Hashimoto H, Baba A Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Hashimoto R, Nagayasu K, Nakazawa T, Hashimoto H, Baba A Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model. Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model. Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34, 7, 2514-2523 The Journal of neuroscience : the official journal of the Society for Neuroscience, 34, 7, 2514-2523 The Journal of neuroscience : the official journal of the Society for Neuroscience, 34, 7, 2514-2523 2014/02 公開
Takahashi A, Nagayasu K, Nishitani N, Kaneko S, Koide T Takahashi A, Nagayasu K, Nishitani N, Kaneko S, Koide T Takahashi A, Nagayasu K, Nishitani N, Kaneko S, Koide T Control of intermale aggression by medial prefrontal cortex activation in the mouse. Control of intermale aggression by medial prefrontal cortex activation in the mouse. Control of intermale aggression by medial prefrontal cortex activation in the mouse. PloS one, 9, 4, e94657 PloS one, 9, 4, e94657 PloS one, 9, 4, e94657 2014 公開
Hazama K, Hayata-Takano A, Uetsuki K, Kasai A, Encho N, Shintani N, Nagayasu K, Hashimoto R, Reglodi D, Miyakawa T, Nakazawa T, Baba A, Hashimoto H Hazama K, Hayata-Takano A, Uetsuki K, Kasai A, Encho N, Shintani N, Nagayasu K, Hashimoto R, Reglodi D, Miyakawa T, Nakazawa T, Baba A, Hashimoto H Hazama K, Hayata-Takano A, Uetsuki K, Kasai A, Encho N, Shintani N, Nagayasu K, Hashimoto R, Reglodi D, Miyakawa T, Nakazawa T, Baba A, Hashimoto H Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice. PloS one, 9, 2 PloS one, 9, 2 PloS one, 9, 2 2014 公開
Nagayasu K, Kitaichi M, Nishitani N, Asaoka N, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Kitaichi M, Nishitani N, Asaoka N, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Kitaichi M, Nishitani N, Asaoka N, Shirakawa H, Nakagawa T, Kaneko S Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: high potency of milnacipran in the augmentation of serotonin release. Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: high potency of milnacipran in the augmentation of serotonin release. Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: high potency of milnacipran in the augmentation of serotonin release. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 16, 10, 2295-2306 The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 16, 10, 2295-2306 The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 16, 10, 2295-2306 2013/11 公開
Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice. Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice. Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice. Stroke; a journal of cerebral circulation, 44, 7, 1981-1987 Stroke; a journal of cerebral circulation, 44, 7, 1981-1987 Stroke; a journal of cerebral circulation, 44, 7, 1981-1987 2013/07 公開
Nakagawa T, Nagayasu K, Nishitani N, Shirakawa H, Sekiguchi K, Ikarashi Y, Kase Y, Kaneko S Nakagawa T, Nagayasu K, Nishitani N, Shirakawa H, Sekiguchi K, Ikarashi Y, Kase Y, Kaneko S Nakagawa T, Nagayasu K, Nishitani N, Shirakawa H, Sekiguchi K, Ikarashi Y, Kase Y, Kaneko S Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α₂A-adrenoceptor. Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α₂A-adrenoceptor. Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α₂A-adrenoceptor. Neuroscience, 227, 336-349 Neuroscience, 227, 336-349 Neuroscience, 227, 336-349 2012/12 公開
Nakagawa T, Suzuki Y, Nagayasu K, Kitaichi M, Shirakawa H, Kaneko S Nakagawa T, Suzuki Y, Nagayasu K, Kitaichi M, Shirakawa H, Kaneko S Nakagawa T, Suzuki Y, Nagayasu K, Kitaichi M, Shirakawa H, Kaneko S Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures. Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures. Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures. PloS one, 6, 9 PloS one, 6, 9 PloS one, 6, 9 2011 公開
Nagayasu K, Yatani Y, Kitaichi M, Kitagawa Y, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Yatani Y, Kitaichi M, Kitagawa Y, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Yatani Y, Kitaichi M, Kitagawa Y, Shirakawa H, Nakagawa T, Kaneko S Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective 5-HT reuptake inhibitors on 5-HT release. Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective 5-HT reuptake inhibitors on 5-HT release. Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective 5-HT reuptake inhibitors on 5-HT release. British journal of pharmacology, 161, 7, 1527-1541 British journal of pharmacology, 161, 7, 1527-1541 British journal of pharmacology, 161, 7, 1527-1541 2010/12 公開
Nagayasu K, Kitaichi M, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Kitaichi M, Shirakawa H, Nakagawa T, Kaneko S Nagayasu K, Kitaichi M, Shirakawa H, Nakagawa T, Kaneko S Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures. Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures. Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures. Journal of pharmacological sciences, 113, 2, 197-201 Journal of pharmacological sciences, 113, 2, 197-201 Journal of pharmacological sciences, 113, 2, 197-201 2010 公開
Higuchi M, Suzuki Y, Yatani Y, Kitagawa Y, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Higuchi M, Suzuki Y, Yatani Y, Kitagawa Y, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Higuchi M, Suzuki Y, Yatani Y, Kitagawa Y, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. Journal of neurochemistry, 106, 6, 2410-2420 Journal of neurochemistry, 106, 6, 2410-2420 Journal of neurochemistry, 106, 6, 2410-2420 2008/09 公開

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外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
挑戦的萌芽研究 代表 細胞体セロトニン遊離を選択的に阻害する遺伝学的ツールの開発と神経回路創薬への応用 (平成28年度分) 2016/04/01〜2017/03/31
挑戦的萌芽研究 代表 細胞体セロトニン遊離を選択的に阻害する遺伝学的ツールの開発と神経回路創薬への応用 (平成29年度分) 2017/04/01〜2018/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2017/04〜2018/03
基礎化学実験 Fundamental Chemical Experiments 後期 全学共通科目 2018/04〜2019/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2018/04〜2019/03