杉山 弘

最終更新日時: 2016/07/27 18:07:10

印刷する

氏名(漢字/フリガナ/アルファベット表記)
杉山 弘/スギヤマ ヒロシ/Sugiyama, Hiroshi
所属部署・職名(部局/所属/講座等/職名)
理学研究科/化学専攻生物化学講座/教授
学部兼担
部局 所属 講座等 職名
理学部
学内兼務
部局 所属 講座等 職名
物質-細胞統合システム拠点 連携主任研究者
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8502 京都市左京区北白川追分町 Kitashirakawa-Oiwakecho, Sakyo-ku, Kyoto, 606-8502
連絡先電話番号
種別 番号
職場 075-753-4002
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
工学修士 京都大学
工学博士 京都大学
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
researchmap URL
https://researchmap.jp/7000009721
研究テーマ
(日本語)
DNAを中心としたケミカルバイオロジー研究
(英語)
Chemical Biology of DNA
研究概要
(日本語)
杉山グループでは核酸の生物有機化学を行っている。合成化学と分子生物学の手法を用いて、核酸の分子認識、反応性と構造について研究している。核酸を物質としてこのように一般的にそして基本的に研究しているグループは他にない。グループでは以下の領域での研究を具体的に行っている。DNAの塩基のアルキル化、水素引き抜き、電子移動によるDNAの修飾についての分子機構の解明。抗癌性抗生物質の作用機構の理解に基づいた配列特異的なアルキル化剤の開発。DNAの局所構造の解析法の開発。細胞の分化や病気の治療を目指した人工遺伝子スイッチの開発を長期的な目標としている。
(英語)
Professor Sugiyama's research interests involve the bioorganic chemistry of nucleic acids. Using the tools of synthetic physical organic chemistry and molecular biology, the Sugiyama group is defining the chemical principles underlying the recognition, reactivity and structure of nucleic acids. There are no other research groups on such a general and fundamental aspect of nucleic acids as a substance.The group utilizes a chemical approach in following areas: Molecular mechanism of DNA modification by DNA base alkylation, hydrogen abstraction and charge transfer. Design of highly efficient sequence-specific DNA acting agents based on understanding of the action mechanism of antitumor antibiotics. Design of unnatural nucleic acid for understanding of nucleic acid structure and function. Development of a method probing DNA local conformation in vivo. The long-range goal is creation of artificial genetic switches for targeted cell differentiation and treatment of many diseases.
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Ohtsuki S, Matsuzaki N, Mohri K, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Ishiyama K, Kadowaki N, Takakura Y, Nishikawa M Ohtsuki S, Matsuzaki N, Mohri K, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Ishiyama K, Kadowaki N, Takakura Y, Nishikawa M Ohtsuki S, Matsuzaki N, Mohri K, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Ishiyama K, Kadowaki N, Takakura Y, Nishikawa M Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells. Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells. Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells. Nucleic acid therapeutics, 25, 5, 245-253 Nucleic acid therapeutics, 25, 5, 245-253 Nucleic acid therapeutics, 25, 5, 245-253 2015/10 公開
Endo M, Takeuchi Y, Suzuki Y, Emura T, Hidaka K, Wang F, Willner I, Sugiyama H Endo M, Takeuchi Y, Suzuki Y, Emura T, Hidaka K, Wang F, Willner I, Sugiyama H Endo M, Takeuchi Y, Suzuki Y, Emura T, Hidaka K, Wang F, Willner I, Sugiyama H Single-Molecule Visualization of the Activity of a Zn(2+) -Dependent DNAzyme. Single-Molecule Visualization of the Activity of a Zn(2+) -Dependent DNAzyme. Single-Molecule Visualization of the Activity of a Zn(2+) -Dependent DNAzyme. Angewandte Chemie (International ed. in English), 54, 36, 10550-10554 Angewandte Chemie (International ed. in English), 54, 36, 10550-10554 Angewandte Chemie (International ed. in English), 54, 36, 10550-10554 2015/09 公開
Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Studying RNAP-promoter interactions using atomic force microscopy. Studying RNAP-promoter interactions using atomic force microscopy. Studying RNAP-promoter interactions using atomic force microscopy. Methods (San Diego, Calif.), 86, 4-9 Methods (San Diego, Calif.), 86, 4-9 Methods (San Diego, Calif.), 86, 4-9 2015/09 公開
Endo M, Xing X, Zhou X, Emura T, Hidaka K, Tuesuwan B, Sugiyama H Endo M, Xing X, Zhou X, Emura T, Hidaka K, Tuesuwan B, Sugiyama H Endo M, Xing X, Zhou X, Emura T, Hidaka K, Tuesuwan B, Sugiyama H Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure. Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure. Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure. ACS nano ACS nano ACS nano 2015/09 公開
Nishida Y, Ohtsuki S, Araie Y, Umeki Y, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Nishida Y, Ohtsuki S, Araie Y, Umeki Y, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Nishida Y, Ohtsuki S, Araie Y, Umeki Y, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells. Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells. Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells. Nanomedicine : nanotechnology, biology, and medicine Nanomedicine : nanotechnology, biology, and medicine Nanomedicine : nanotechnology, biology, and medicine 2015/09 公開
Yang Y, Goetzfried MA, Hidaka K, You M, Tan W, Sugiyama H, Endo M Yang Y, Goetzfried MA, Hidaka K, You M, Tan W, Sugiyama H, Endo M Yang Y, Goetzfried MA, Hidaka K, You M, Tan W, Sugiyama H, Endo M Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure. Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure. Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure. Nano letters Nano letters Nano letters 2015/09 公開
Saha A, Hashiya F, Kizaki S, Asamitsu S, Hashiya K, Bando T, Sugiyama H Saha A, Hashiya F, Kizaki S, Asamitsu S, Hashiya K, Bando T, Sugiyama H Saha A, Hashiya F, Kizaki S, Asamitsu S, Hashiya K, Bando T, Sugiyama H A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA. A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA. A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA. Chemical communications (Cambridge, England), 51, 77, 14485-14488 Chemical communications (Cambridge, England), 51, 77, 14485-14488 Chemical communications (Cambridge, England), 51, 77, 14485-14488 2015/09 公開
Tashiro R, Iwamoto M, Morinaga H, Emura T, Hidaka K, Endo M, Sugiyama H Tashiro R, Iwamoto M, Morinaga H, Emura T, Hidaka K, Endo M, Sugiyama H Tashiro R, Iwamoto M, Morinaga H, Emura T, Hidaka K, Endo M, Sugiyama H Linking two DNA duplexes with a rigid linker for DNA nanotechnology. Linking two DNA duplexes with a rigid linker for DNA nanotechnology. Linking two DNA duplexes with a rigid linker for DNA nanotechnology. Nucleic acids research, 43, 14, 6692-6700 Nucleic acids research, 43, 14, 6692-6700 Nucleic acids research, 43, 14, 6692-6700 2015/08 公開
Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Lipid-bilayer-assisted two-dimensional self-assembly of DNA origami nanostructures. Lipid-bilayer-assisted two-dimensional self-assembly of DNA origami nanostructures. Lipid-bilayer-assisted two-dimensional self-assembly of DNA origami nanostructures. Nature communications, 6, 8052 Nature communications, 6, 8052 Nature communications, 6, 8052 2015/08 公開
Taylor RD, Chandran A, Kashiwazaki G, Hashiya K, Bando T, Nagase H, Sugiyama H Taylor RD, Chandran A, Kashiwazaki G, Hashiya K, Bando T, Nagase H, Sugiyama H Taylor RD, Chandran A, Kashiwazaki G, Hashiya K, Bando T, Nagase H, Sugiyama H Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates. Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates. Selective Targeting of the KRAS Codon 12 Mutation Sequence by Pyrrole-Imidazole Polyamide seco-CBI Conjugates. Chemistry (Weinheim an der Bergstrasse, Germany) Chemistry (Weinheim an der Bergstrasse, Germany) Chemistry (Weinheim an der Bergstrasse, Germany) 2015/08 公開
Patel S, Chueng SD, Yin PT, Dardir K, Song Z, Pasquale N, Kwan K, Sugiyama H, Lee KB Patel S, Chueng SD, Yin PT, Dardir K, Song Z, Pasquale N, Kwan K, Sugiyama H, Lee KB Patel S, Chueng SD, Yin PT, Dardir K, Song Z, Pasquale N, Kwan K, Sugiyama H, Lee KB Induction of Stem-Cell-Derived Functional Neurons by NanoScript-Based Gene Repression. Induction of Stem-Cell-Derived Functional Neurons by NanoScript-Based Gene Repression. Induction of Stem-Cell-Derived Functional Neurons by NanoScript-Based Gene Repression. Angewandte Chemie (International ed. in English) Angewandte Chemie (International ed. in English) Angewandte Chemie (International ed. in English) 2015/08 公開
Endo M, Sugiyama H Endo M, Sugiyama H Endo M, Sugiyama H DNA nanotechnology: Measuring chloride in live cells. DNA nanotechnology: Measuring chloride in live cells. DNA nanotechnology: Measuring chloride in live cells. Nature nanotechnology, 10, 7, 569-570 Nature nanotechnology, 10, 7, 569-570 Nature nanotechnology, 10, 7, 569-570 2015/07 公開
Goto N, Bazar G, Kovacs Z, Kunisada M, Morita H, Kizaki S, Sugiyama H, Tsenkova R, Nishigori C Goto N, Bazar G, Kovacs Z, Kunisada M, Morita H, Kizaki S, Sugiyama H, Tsenkova R, Nishigori C Goto N, Bazar G, Kovacs Z, Kunisada M, Morita H, Kizaki S, Sugiyama H, Tsenkova R, Nishigori C Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics. Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics. Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics. Scientific reports, 5, 11808 Scientific reports, 5, 11808 Scientific reports, 5, 11808 2015/07 公開
Patel S, Yin PT, Sugiyama H, Lee KB Patel S, Yin PT, Sugiyama H, Lee KB Patel S, Yin PT, Sugiyama H, Lee KB Inducing Stem Cell Myogenesis Using NanoScript. Inducing Stem Cell Myogenesis Using NanoScript. Inducing Stem Cell Myogenesis Using NanoScript. ACS nano, 9, 7, 6909-6917 ACS nano, 9, 7, 6909-6917 ACS nano, 9, 7, 6909-6917 2015/07 公開
Han L, Pandian GN, Chandran A, Sato S, Taniguchi J, Kashiwazaki G, Sawatani Y, Hashiya K, Bando T, Xu Y, Qian X, Sugiyama H Han L, Pandian GN, Chandran A, Sato S, Taniguchi J, Kashiwazaki G, Sawatani Y, Hashiya K, Bando T, Xu Y, Qian X, Sugiyama H Han L, Pandian GN, Chandran A, Sato S, Taniguchi J, Kashiwazaki G, Sawatani Y, Hashiya K, Bando T, Xu Y, Qian X, Sugiyama H A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network. A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network. A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network. Angewandte Chemie (International ed. in English), 54, 30, 8700-8703 Angewandte Chemie (International ed. in English), 54, 30, 8700-8703 Angewandte Chemie (International ed. in English), 54, 30, 8700-8703 2015/07 公開
Syed J, Chandran A, Pandian GN, Taniguchi J, Sato S, Hashiya K, Kashiwazaki G, Bando T, Sugiyama H Syed J, Chandran A, Pandian GN, Taniguchi J, Sato S, Hashiya K, Kashiwazaki G, Bando T, Sugiyama H Syed J, Chandran A, Pandian GN, Taniguchi J, Sato S, Hashiya K, Kashiwazaki G, Bando T, Sugiyama H A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts. Chembiochem : a European journal of chemical biology, 16, 10, 1497-1501 Chembiochem : a European journal of chemical biology, 16, 10, 1497-1501 Chembiochem : a European journal of chemical biology, 16, 10, 1497-1501 2015/07 公開
Rajendran A, Endo M, Hidaka K, Teulade-Fichou MP, Mergny JL, Sugiyama H Rajendran A, Endo M, Hidaka K, Teulade-Fichou MP, Mergny JL, Sugiyama H Rajendran A, Endo M, Hidaka K, Teulade-Fichou MP, Mergny JL, Sugiyama H Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions. Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions. Small molecule binding to a G-hairpin and a G-triplex: a new insight into anticancer drug design targeting G-rich regions. Chemical communications (Cambridge, England), 51, 44, 9181-9184 Chemical communications (Cambridge, England), 51, 44, 9181-9184 Chemical communications (Cambridge, England), 51, 44, 9181-9184 2015/06 公開
Li Y, Sugiyama H Li Y, Sugiyama H Li Y, Sugiyama H Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA. Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA. Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA. Chemical communications (Cambridge, England), 51, 42, 8861-8864 Chemical communications (Cambridge, England), 51, 42, 8861-8864 Chemical communications (Cambridge, England), 51, 42, 8861-8864 2015/05 公開
Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate. Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate. Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate. Nature communications, 6, 6706 Nature communications, 6, 6706 Nature communications, 6, 6706 2015/04 公開
Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Suzuki Y, Endo M, Sugiyama H Mimicking membrane-related biological events by DNA origami nanotechnology. Mimicking membrane-related biological events by DNA origami nanotechnology. Mimicking membrane-related biological events by DNA origami nanotechnology. ACS nano, 9, 4, 3418-3420 ACS nano, 9, 4, 3418-3420 ACS nano, 9, 4, 3418-3420 2015/04 公開
Patel S, Pongkulapa T, Yin PT, Pandian GN, Rathnam C, Bando T, Vaijayanthi T, Sugiyama H, Lee KB Patel S, Pongkulapa T, Yin PT, Pandian GN, Rathnam C, Bando T, Vaijayanthi T, Sugiyama H, Lee KB Patel S, Pongkulapa T, Yin PT, Pandian GN, Rathnam C, Bando T, Vaijayanthi T, Sugiyama H, Lee KB Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells. Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells. Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells. Journal of the American Chemical Society, 137, 14, 4598-4601 Journal of the American Chemical Society, 137, 14, 4598-4601 Journal of the American Chemical Society, 137, 14, 4598-4601 2015/04 公開
Mohri K, Kusuki E, Ohtsuki S, Takahashi N, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Mohri K, Kusuki E, Ohtsuki S, Takahashi N, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Mohri K, Kusuki E, Ohtsuki S, Takahashi N, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells. Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells. Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells. Biomacromolecules, 16, 4, 1095-1101 Biomacromolecules, 16, 4, 1095-1101 Biomacromolecules, 16, 4, 1095-1101 2015/04 公開
Guo C, Kawamoto Y, Asamitsu S, Sawatani Y, Hashiya K, Bando T, Sugiyama H Guo C, Kawamoto Y, Asamitsu S, Sawatani Y, Hashiya K, Bando T, Sugiyama H Guo C, Kawamoto Y, Asamitsu S, Sawatani Y, Hashiya K, Bando T, Sugiyama H Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences. Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences. Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences. Bioorganic & medicinal chemistry, 23, 4, 855-860 Bioorganic & medicinal chemistry, 23, 4, 855-860 Bioorganic & medicinal chemistry, 23, 4, 855-860 2015/02 公開
Anandhakumar C, Kizaki S, Bando T, Pandian GN, Sugiyama H Anandhakumar C, Kizaki S, Bando T, Pandian GN, Sugiyama H Anandhakumar C, Kizaki S, Bando T, Pandian GN, Sugiyama H Advancing small-molecule-based chemical biology with next-generation sequencing technologies. Advancing small-molecule-based chemical biology with next-generation sequencing technologies. Advancing small-molecule-based chemical biology with next-generation sequencing technologies. Chembiochem : a European journal of chemical biology, 16, 1, 20-38 Chembiochem : a European journal of chemical biology, 16, 1, 20-38 Chembiochem : a European journal of chemical biology, 16, 1, 20-38 2015/01 公開
Shibata T, Suzuki Y, Sugiyama H, Endo M, Saito H Shibata T, Suzuki Y, Sugiyama H, Endo M, Saito H Shibata T, Suzuki Y, Sugiyama H, Endo M, Saito H Folding RNA-Protein Complex into Designed Nanostructures. Folding RNA-Protein Complex into Designed Nanostructures. Folding RNA-Protein Complex into Designed Nanostructures. Methods in molecular biology (Clifton, N.J.), 1316, 169-179 Methods in molecular biology (Clifton, N.J.), 1316, 169-179 Methods in molecular biology (Clifton, N.J.), 1316, 169-179 2015 公開
Igarashi J, Fukuda N, Inoue T, Nakai S, Saito K, Fujiwara K, Matsuda H, Ueno T, Matsumoto Y, Watanabe T, Nagase H, Bando T, Sugiyama H, Itoh T, Soma M Igarashi J, Fukuda N, Inoue T, Nakai S, Saito K, Fujiwara K, Matsuda H, Ueno T, Matsumoto Y, Watanabe T, Nagase H, Bando T, Sugiyama H, Itoh T, Soma M Igarashi J, Fukuda N, Inoue T, Nakai S, Saito K, Fujiwara K, Matsuda H, Ueno T, Matsumoto Y, Watanabe T, Nagase H, Bando T, Sugiyama H, Itoh T, Soma M Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model. Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model. Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model. PloS one, 10, 5, e0125295 PloS one, 10, 5, e0125295 PloS one, 10, 5, e0125295 2015 公開
Umemura A, Oeda T, Yamamoto K, Tomita S, Kohsaka M, Park K, Sugiyama H, Sawada H Umemura A, Oeda T, Yamamoto K, Tomita S, Kohsaka M, Park K, Sugiyama H, Sawada H Umemura A, Oeda T, Yamamoto K, Tomita S, Kohsaka M, Park K, Sugiyama H, Sawada H Baseline Plasma C-Reactive Protein Concentrations and Motor Prognosis in Parkinson Disease. Baseline Plasma C-Reactive Protein Concentrations and Motor Prognosis in Parkinson Disease. Baseline Plasma C-Reactive Protein Concentrations and Motor Prognosis in Parkinson Disease. PloS one, 10, 8, e0136722 PloS one, 10, 8, e0136722 PloS one, 10, 8, e0136722 2015 公開
Hashiya F, Saha A, Kizaki S, Li Y, Sugiyama H Hashiya F, Saha A, Kizaki S, Li Y, Sugiyama H Hashiya F, Saha A, Kizaki S, Li Y, Sugiyama H Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA. Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA. Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA. Nucleic acids research, 42, 22, 13469-13473 Nucleic acids research, 42, 22, 13469-13473 Nucleic acids research, 42, 22, 13469-13473 2014/12 公開
Anandhakumar C, Li Y, Kizaki S, Pandian GN, Hashiya K, Bando T, Sugiyama H Anandhakumar C, Li Y, Kizaki S, Pandian GN, Hashiya K, Bando T, Sugiyama H Anandhakumar C, Li Y, Kizaki S, Pandian GN, Hashiya K, Bando T, Sugiyama H Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine. Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine. Next-generation sequencing studies guide the design of pyrrole-imidazole polyamides with improved binding specificity by the addition of β-alanine. Chembiochem : a European journal of chemical biology, 15, 18, 2647-2651 Chembiochem : a European journal of chemical biology, 15, 18, 2647-2651 Chembiochem : a European journal of chemical biology, 15, 18, 2647-2651 2014/12 公開
Pandian GN, Sato S, Anandhakumar C, Taniguchi J, Takashima K, Syed J, Han L, Saha A, Bando T, Nagase H, Sugiyama H Pandian GN, Sato S, Anandhakumar C, Taniguchi J, Takashima K, Syed J, Han L, Saha A, Bando T, Nagase H, Sugiyama H Pandian GN, Sato S, Anandhakumar C, Taniguchi J, Takashima K, Syed J, Han L, Saha A, Bando T, Nagase H, Sugiyama H Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts. Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts. Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts. ACS chemical biology, 9, 12, 2729-2736 ACS chemical biology, 9, 12, 2729-2736 ACS chemical biology, 9, 12, 2729-2736 2014/12 公開
Endo M, Takeuchi Y, Emura T, Hidaka K, Sugiyama H Endo M, Takeuchi Y, Emura T, Hidaka K, Sugiyama H Endo M, Takeuchi Y, Emura T, Hidaka K, Sugiyama H Preparation of chemically modified RNA origami nanostructures. Preparation of chemically modified RNA origami nanostructures. Preparation of chemically modified RNA origami nanostructures. Chemistry (Weinheim an der Bergstrasse, Germany), 20, 47, 15330-15333 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 47, 15330-15333 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 47, 15330-15333 2014/11 公開
Ghimire C, Park S, Iida K, Yangyuoru P, Otomo H, Yu Z, Nagasawa K, Sugiyama H, Mao H Ghimire C, Park S, Iida K, Yangyuoru P, Otomo H, Yu Z, Nagasawa K, Sugiyama H, Mao H Ghimire C, Park S, Iida K, Yangyuoru P, Otomo H, Yu Z, Nagasawa K, Sugiyama H, Mao H Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. Journal of the American Chemical Society, 136, 44, 15537-15544 Journal of the American Chemical Society, 136, 44, 15537-15544 Journal of the American Chemical Society, 136, 44, 15537-15544 2014/11 公開
Takenaka T, Endo M, Suzuki Y, Yang Y, Emura T, Hidaka K, Kato T, Miyata T, Namba K, Sugiyama H Takenaka T, Endo M, Suzuki Y, Yang Y, Emura T, Hidaka K, Kato T, Miyata T, Namba K, Sugiyama H Takenaka T, Endo M, Suzuki Y, Yang Y, Emura T, Hidaka K, Kato T, Miyata T, Namba K, Sugiyama H Photoresponsive DNA nanocapsule having an open/close system for capture and release of nanomaterials. Photoresponsive DNA nanocapsule having an open/close system for capture and release of nanomaterials. Photoresponsive DNA nanocapsule having an open/close system for capture and release of nanomaterials. Chemistry (Weinheim an der Bergstrasse, Germany), 20, 46, 14951-14954 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 46, 14951-14954 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 46, 14951-14954 2014/11 公開
Syed J, Pandian GN, Sato S, Taniguchi J, Chandran A, Hashiya K, Bando T, Sugiyama H Syed J, Pandian GN, Sato S, Taniguchi J, Chandran A, Hashiya K, Bando T, Sugiyama H Syed J, Pandian GN, Sato S, Taniguchi J, Chandran A, Hashiya K, Bando T, Sugiyama H Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide. Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide. Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide. Chemistry & biology, 21, 10, 1370-1380 Chemistry & biology, 21, 10, 1370-1380 Chemistry & biology, 21, 10, 1370-1380 2014/10 公開
Saha A, Pandian GN, Sato S, Taniguchi J, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Saha A, Pandian GN, Sato S, Taniguchi J, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Saha A, Pandian GN, Sato S, Taniguchi J, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Chemical modification of a synthetic small molecule boosts its biological efficacy against pluripotency genes in mouse fibroblasts. Chemical modification of a synthetic small molecule boosts its biological efficacy against pluripotency genes in mouse fibroblasts. Chemical modification of a synthetic small molecule boosts its biological efficacy against pluripotency genes in mouse fibroblasts. ChemMedChem, 9, 10, 2374-2380 ChemMedChem, 9, 10, 2374-2380 ChemMedChem, 9, 10, 2374-2380 2014/10 公開
Patel S, Jung D, Yin PT, Carlton P, Yamamoto M, Bando T, Sugiyama H, Lee KB Patel S, Jung D, Yin PT, Carlton P, Yamamoto M, Bando T, Sugiyama H, Lee KB Patel S, Jung D, Yin PT, Carlton P, Yamamoto M, Bando T, Sugiyama H, Lee KB NanoScript: a nanoparticle-based artificial transcription factor for effective gene regulation. NanoScript: a nanoparticle-based artificial transcription factor for effective gene regulation. NanoScript: a nanoparticle-based artificial transcription factor for effective gene regulation. ACS nano, 8, 9, 8959-8967 ACS nano, 8, 9, 8959-8967 ACS nano, 8, 9, 8959-8967 2014/09 公開
Asamitsu S, Kawamoto Y, Hashiya F, Hashiya K, Yamamoto M, Kizaki S, Bando T, Sugiyama H Asamitsu S, Kawamoto Y, Hashiya F, Hashiya K, Yamamoto M, Kizaki S, Bando T, Sugiyama H Asamitsu S, Kawamoto Y, Hashiya F, Hashiya K, Yamamoto M, Kizaki S, Bando T, Sugiyama H Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats. Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats. Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats. Bioorganic & medicinal chemistry, 22, 17, 4646-4657 Bioorganic & medicinal chemistry, 22, 17, 4646-4657 Bioorganic & medicinal chemistry, 22, 17, 4646-4657 2014/09 公開
Taylor RD, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Taylor RD, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Taylor RD, Kawamoto Y, Hashiya K, Bando T, Sugiyama H Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates. Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates. Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates. Chemistry, an Asian journal, 9, 9, 2527-2533 Chemistry, an Asian journal, 9, 9, 2527-2533 Chemistry, an Asian journal, 9, 9, 2527-2533 2014/09 公開
Osada E, Suzuki Y, Hidaka K, Ohno H, Sugiyama H, Endo M, Saito H Osada E, Suzuki Y, Hidaka K, Ohno H, Sugiyama H, Endo M, Saito H Osada E, Suzuki Y, Hidaka K, Ohno H, Sugiyama H, Endo M, Saito H Engineering RNA-protein complexes with different shapes for imaging and therapeutic applications. Engineering RNA-protein complexes with different shapes for imaging and therapeutic applications. Engineering RNA-protein complexes with different shapes for imaging and therapeutic applications. ACS nano, 8, 8, 8130-8140 ACS nano, 8, 8, 8130-8140 ACS nano, 8, 8, 8130-8140 2014/08 公開
Hirata A, Nokihara K, Kawamoto Y, Bando T, Sasaki A, Ide S, Maeshima K, Kasama T, Sugiyama H Hirata A, Nokihara K, Kawamoto Y, Bando T, Sasaki A, Ide S, Maeshima K, Kasama T, Sugiyama H Hirata A, Nokihara K, Kawamoto Y, Bando T, Sasaki A, Ide S, Maeshima K, Kasama T, Sugiyama H Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. Structural evaluation of tandem hairpin pyrrole-imidazole polyamides recognizing human telomeres. Journal of the American Chemical Society, 136, 32, 11546-11554 Journal of the American Chemical Society, 136, 32, 11546-11554 Journal of the American Chemical Society, 136, 32, 11546-11554 2014/08 公開
Rajendran A, Endo M, Hidaka K, Shimada N, Maruyama A, Sugiyama H Rajendran A, Endo M, Hidaka K, Shimada N, Maruyama A, Sugiyama H Rajendran A, Endo M, Hidaka K, Shimada N, Maruyama A, Sugiyama H A lock-and-key mechanism for the controllable fabrication of DNA origami structures. A lock-and-key mechanism for the controllable fabrication of DNA origami structures. A lock-and-key mechanism for the controllable fabrication of DNA origami structures. Chemical communications (Cambridge, England), 50, 63, 8743-8746 Chemical communications (Cambridge, England), 50, 63, 8743-8746 Chemical communications (Cambridge, England), 50, 63, 8743-8746 2014/08 公開
Koirala D, Shrestha P, Emura T, Hidaka K, Mandal S, Endo M, Sugiyama H, Mao H Koirala D, Shrestha P, Emura T, Hidaka K, Mandal S, Endo M, Sugiyama H, Mao H Koirala D, Shrestha P, Emura T, Hidaka K, Mandal S, Endo M, Sugiyama H, Mao H Single-molecule mechanochemical sensing using DNA origami nanostructures. Single-molecule mechanochemical sensing using DNA origami nanostructures. Single-molecule mechanochemical sensing using DNA origami nanostructures. Angewandte Chemie (International ed. in English), 53, 31, 8137-8141 Angewandte Chemie (International ed. in English), 53, 31, 8137-8141 Angewandte Chemie (International ed. in English), 53, 31, 8137-8141 2014/07 公開
Endo M, Yamamoto S, Emura T, Hidaka K, Morone N, Heuser JE, Sugiyama H Endo M, Yamamoto S, Emura T, Hidaka K, Morone N, Heuser JE, Sugiyama H Endo M, Yamamoto S, Emura T, Hidaka K, Morone N, Heuser JE, Sugiyama H Helical DNA origami tubular structures with various sizes and arrangements. Helical DNA origami tubular structures with various sizes and arrangements. Helical DNA origami tubular structures with various sizes and arrangements. Angewandte Chemie (International ed. in English), 53, 29, 7484-7490 Angewandte Chemie (International ed. in English), 53, 29, 7484-7490 Angewandte Chemie (International ed. in English), 53, 29, 7484-7490 2014/07 公開
Suzuki Y, Endo M, Cañas C, Ayora S, Alonso JC, Sugiyama H, Takeyasu K Suzuki Y, Endo M, Cañas C, Ayora S, Alonso JC, Sugiyama H, Takeyasu K Suzuki Y, Endo M, Cañas C, Ayora S, Alonso JC, Sugiyama H, Takeyasu K Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure. Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure. Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure. Nucleic acids research, 42, 11, 7421-7428 Nucleic acids research, 42, 11, 7421-7428 Nucleic acids research, 42, 11, 7421-7428 2014/06 公開
Endo M, Sugiyama H Endo M, Sugiyama H Endo M, Sugiyama H Single-molecule imaging of dynamic motions of biomolecules in DNA origami nanostructures using high-speed atomic force microscopy. Single-molecule imaging of dynamic motions of biomolecules in DNA origami nanostructures using high-speed atomic force microscopy. Single-molecule imaging of dynamic motions of biomolecules in DNA origami nanostructures using high-speed atomic force microscopy. Accounts of chemical research, 47, 6, 1645-1653 Accounts of chemical research, 47, 6, 1645-1653 Accounts of chemical research, 47, 6, 1645-1653 2014/06 公開
Yamamoto S, De D, Hidaka K, Kim KK, Endo M, Sugiyama H Yamamoto S, De D, Hidaka K, Kim KK, Endo M, Sugiyama H Yamamoto S, De D, Hidaka K, Kim KK, Endo M, Sugiyama H Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame. Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame. Single molecule visualization and characterization of Sox2-Pax6 complex formation on a regulatory DNA element using a DNA origami frame. Nano letters, 14, 5, 2286-2292 Nano letters, 14, 5, 2286-2292 Nano letters, 14, 5, 2286-2292 2014/05 公開
Yang Y, Endo M, Suzuki Y, Hidaka K, Sugiyama H Yang Y, Endo M, Suzuki Y, Hidaka K, Sugiyama H Yang Y, Endo M, Suzuki Y, Hidaka K, Sugiyama H Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe. Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe. Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe. Chemical communications (Cambridge, England), 50, 32, 4211-4213 Chemical communications (Cambridge, England), 50, 32, 4211-4213 Chemical communications (Cambridge, England), 50, 32, 4211-4213 2014/04 公開
Rajendran A, Endo M, Hidaka K, Sugiyama H Rajendran A, Endo M, Hidaka K, Sugiyama H Rajendran A, Endo M, Hidaka K, Sugiyama H Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates. Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates. Direct and single-molecule visualization of the solution-state structures of G-hairpin and G-triplex intermediates. Angewandte Chemie (International ed. in English), 53, 16, 4107-4112 Angewandte Chemie (International ed. in English), 53, 16, 4107-4112 Angewandte Chemie (International ed. in English), 53, 16, 4107-4112 2014/04 公開
Pandian GN, Taniguchi J, Sugiyama H Pandian GN, Taniguchi J, Sugiyama H Pandian GN, Taniguchi J, Sugiyama H Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control. Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control. Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control. Clinical and translational medicine, 3, 1, 6 Clinical and translational medicine, 3, 1, 6 Clinical and translational medicine, 3, 1, 6 2014/03 公開
Yamamoto M, Bando T, Kawamoto Y, Taylor RD, Hashiya K, Sugiyama H Yamamoto M, Bando T, Kawamoto Y, Taylor RD, Hashiya K, Sugiyama H M. Yamamoto; T. Bando; Y. Kawamoto; R.D. Taylor; K. Hashiya; H. Sugiyama Specific alkylation of human telomere repeat sequences by a tandem-hairpin motif of pyrrole-imidazole polyamides with indole-seco-CBI. Specific alkylation of human telomere repeat sequences by a tandem-hairpin motif of pyrrole-imidazole polyamides with indole-seco-CBI. Specific alkylation of human telomere repeat sequences by a tandem-hairpin motif of pyrrole-imidazole polyamides with indole-seco-CBI Bioconjugate chemistry, 25, 3, 552-559 Bioconjugate chemistry, 25, 3, 552-559 Bioconjugate Chemistry, 25, 3, 552-559 2014/03 英語 公開
Suzuki Y, Endo M, Yang Y, Sugiyama H Suzuki Y, Endo M, Yang Y, Sugiyama H Y. Suzuki; M. Endo; Y. Yang; H. Sugiyama Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface. Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface. Dynamic assembly/disassembly processes of photoresponsive DNA origami nanostructures directly visualized on a lipid membrane surface Journal of the American Chemical Society, 136, 5, 1714-1717 Journal of the American Chemical Society, 136, 5, 1714-1717 Journal of the American Chemical Society, 136, 5, 1714-1717 2014/02 英語 公開
Park S, Otomo H, Zheng L, Sugiyama H Park S, Otomo H, Zheng L, Sugiyama H S. Park; H. Otomo; L. Zheng; H. Sugiyama Highly emissive deoxyguanosine analogue capable of direct visualization of B-Z transition. Highly emissive deoxyguanosine analogue capable of direct visualization of B-Z transition. Highly emissive deoxyguanosine analogue capable of direct visualization of B-Z transition Chemical communications (Cambridge, England), 50, 13, 1573-1575 Chemical communications (Cambridge, England), 50, 13, 1573-1575 Chemical Communications, 50, 13, 1573-1575 2014/02 英語 公開
Pandian GN, Taniguchi J, Junetha S, Sato S, Han L, Saha A, AnandhaKumar C, Bando T, Nagase H, Vaijayanthi T, Taylor RD, Sugiyama H Pandian GN, Taniguchi J, Junetha S, Sato S, Han L, Saha A, AnandhaKumar C, Bando T, Nagase H, Vaijayanthi T, Taylor RD, Sugiyama H G.N. Pandian; J. Taniguchi; S. Junetha; S. Sato; L. Han; A. Saha; C. Anandhakumar; T. Bando; H. Nagase; T. Vaijayanthi; R.D. Taylor; H. Sugiyama Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts. Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts. Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts Scientific reports, 4, 3843 Scientific reports, 4, 3843 Scientific Reports, 4, 3843 2014/01 英語 公開
Taylor RD, Asamitsu S, Takenaka T, Yamamoto M, Hashiya K, Kawamoto Y, Bando T, Nagase H, Sugiyama H Taylor RD, Asamitsu S, Takenaka T, Yamamoto M, Hashiya K, Kawamoto Y, Bando T, Nagase H, Sugiyama H Taylor RD, Asamitsu S, Takenaka T, Yamamoto M, Hashiya K, Kawamoto Y, Bando T, Nagase H, Sugiyama H Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates. Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates. Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates. Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1310-1317 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1310-1317 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1310-1317 2014/01 公開
Sannohe Y, Kizaki S, Kanesato S, Fujiwara A, Li Y, Morinaga H, Tashiro R, Sugiyama H Sannohe Y, Kizaki S, Kanesato S, Fujiwara A, Li Y, Morinaga H, Tashiro R, Sugiyama H Sannohe Y, Kizaki S, Kanesato S, Fujiwara A, Li Y, Morinaga H, Tashiro R, Sugiyama H Controlling electron rebound within four-base π-stacks in Z-DNA by changing the sugar moiety from deoxy- to ribonucleotide. Controlling electron rebound within four-base π-stacks in Z-DNA by changing the sugar moiety from deoxy- to ribonucleotide. Controlling electron rebound within four-base π-stacks in Z-DNA by changing the sugar moiety from deoxy- to ribonucleotide. Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1223-1225 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1223-1225 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 5, 1223-1225 2014/01 公開
Yamamoto M, Bando T, Morinaga H, Kawamoto Y, Hashiya K, Sugiyama H Yamamoto M, Bando T, Morinaga H, Kawamoto Y, Hashiya K, Sugiyama H M. Yamamoto; T. Bando; H. Morinaga; Y. Kawamoto; K. Hashiya; H. Sugiyama Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers. Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers. Sequence-specific DNA recognition by cyclic pyrrole-imidazole cysteine-derived polyamide dimers Chemistry (Weinheim an der Bergstrasse, Germany), 20, 3, 752-759 Chemistry (Weinheim an der Bergstrasse, Germany), 20, 3, 752-759 Chemistry - A European Journal, 20, 3, 752-759 2014/01 英語 公開
Suzuki Y, Endo M, Katsuda Y, Ou K, Hidaka K, Sugiyama H Suzuki Y, Endo M, Katsuda Y, Ou K, Hidaka K, Sugiyama H Y. Suzuki; M. Endo; Y. Katsuda; K. Ou; K. Hidaka; H. Sugiyama DNA origami based visualization system for studying site-specific recombination events. DNA origami based visualization system for studying site-specific recombination events. DNA origami based visualization system for studying site-specific recombination events Journal of the American Chemical Society, 136, 1, 211-218 Journal of the American Chemical Society, 136, 1, 211-218 Journal of the American Chemical Society, 136, 1, 211-218 2014/01 英語 公開
Rajendran A, Endo M, Sugiyama H Rajendran A, Endo M, Sugiyama H A. Rajendran; M. Endo; H. Sugiyama State-of-the-art high-speed atomic force microscopy for investigation of single-molecular dynamics of proteins. State-of-the-art high-speed atomic force microscopy for investigation of single-molecular dynamics of proteins. State-of-the-art high-speed atomic force microscopy for investigation of single-molecular dynamics of proteins Chemical reviews, 114, 2, 1493-1520 Chemical reviews, 114, 2, 1493-1520 Chemical Reviews, 114, 2, 1493-1520 2014/01 英語 公開
Kizaki S, Sugiyama H Kizaki S, Sugiyama H S. Kizaki; H. Sugiyama CGmCGCG is a versatile substrate with which to evaluate Tet protein activity. CGmCGCG is a versatile substrate with which to evaluate Tet protein activity. CGmCGCG is a versatile substrate with which to evaluate Tet protein activity Organic & biomolecular chemistry, 12, 1, 104-107 Organic & biomolecular chemistry, 12, 1, 104-107 Organic and Biomolecular Chemistry, 12, 1, 104-107 2014/01 英語 公開
Chen FY, Park S, Otomo H, Sakashita S, Sugiyama H Chen FY, Park S, Otomo H, Sakashita S, Sugiyama H Chen FY, Park S, Otomo H, Sakashita S, Sugiyama H Investigation of B-Z transitions with DNA oligonucleotides containing 8-methylguanine. Investigation of B-Z transitions with DNA oligonucleotides containing 8-methylguanine. Investigation of B-Z transitions with DNA oligonucleotides containing 8-methylguanine. Artificial DNA, PNA & XNA, 5, 1, e28226 Artificial DNA, PNA & XNA, 5, 1, e28226 Artificial DNA, PNA & XNA, 5, 1, e28226 2014 公開
Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Gorelick RJ, Sugiyama H Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Gorelick RJ, Sugiyama H A. Rajendran; M. Endo; K. Hidaka; P.L.T. Tran; J.-L. Mergny; R.J. Gorelick; H. Sugiyama HIV-1 nucleocapsid proteins as molecular chaperones for tetramolecular antiparallel G-quadruplex formation. HIV-1 nucleocapsid proteins as molecular chaperones for tetramolecular antiparallel G-quadruplex formation. HIV-1 nucleocapsid proteins as molecular chaperones for tetramolecular antiparallel g-quadruplex formation Journal of the American Chemical Society, 135, 49, 18575-18585 Journal of the American Chemical Society, 135, 49, 18575-18585 Journal of the American Chemical Society, 135, 49, 18575-18585 2013/12 英語 公開
Endo M, Inoue M, Suzuki Y, Masui C, Morinaga H, Hidaka K, Sugiyama H Endo M, Inoue M, Suzuki Y, Masui C, Morinaga H, Hidaka K, Sugiyama H M. Endo; M. Inoue; Y. Suzuki; C. Masui; H. Morinaga; K. Hidaka; H. Sugiyama Regulation of B-Z conformational transition and complex formation with a Z-form binding protein by introduction of constraint to double-stranded DNA by using a DNA nanoscaffold. Regulation of B-Z conformational transition and complex formation with a Z-form binding protein by introduction of constraint to double-stranded DNA by using a DNA nanoscaffold. Regulation of B-Z conformational transition and complex formation with a z-form binding protein by introduction of constraint to double-stranded DNA by using a DNA nanoscaffold Chemistry (Weinheim an der Bergstrasse, Germany), 19, 50, 16887-16890 Chemistry (Weinheim an der Bergstrasse, Germany), 19, 50, 16887-16890 Chemistry - A European Journal, 19, 50, 16887-16890 2013/12 英語 公開
Kameshima W, Ishizuka T, Minoshima M, Yamamoto M, Sugiyama H, Xu Y, Komiyama M Kameshima W, Ishizuka T, Minoshima M, Yamamoto M, Sugiyama H, Xu Y, Komiyama M W. Kameshima; T. Ishizuka; M. Minoshima; M. Yamamoto; H. Sugiyama; Y. Xu; M. Komiyama Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA. Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA. Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA Angewandte Chemie (International ed. in English), 52, 51, 13681-13684 Angewandte Chemie (International ed. in English), 52, 51, 13681-13684 Angewandte Chemie - International Edition, 52, 51, 13681-13684 2013/12 英語 公開
Han L, Pandian GN, Junetha S, Sato S, Anandhakumar C, Taniguchi J, Saha A, Bando T, Nagase H, Sugiyama H Han L, Pandian GN, Junetha S, Sato S, Anandhakumar C, Taniguchi J, Saha A, Bando T, Nagase H, Sugiyama H L. Han; G.N. Pandian; S. Junetha; S. Sato; C. Anandhakumar; J. Taniguchi; A. Saha; T. Bando; H. Nagase; H. Sugiyama A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell. A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell. A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell Angewandte Chemie (International ed. in English), 52, 50, 13410-13413 Angewandte Chemie (International ed. in English), 52, 50, 13410-13413 Angewandte Chemie - International Edition, 52, 50, 13410-13413 2013/12 英語 公開
Wu YL, Pandian GN, Ding YP, Zhang W, Tanaka Y, Sugiyama H Wu YL, Pandian GN, Ding YP, Zhang W, Tanaka Y, Sugiyama H Y.-L. Wu; G.N. Pandian; Y.-P. Ding; W. Zhang; Y. Tanaka; H. Sugiyama Clinical grade iPS cells: need for versatile small molecules and optimal cell sources. Clinical grade iPS cells: need for versatile small molecules and optimal cell sources. Clinical grade iPS cells: Need for versatile small molecules and optimal cell sources Chemistry & biology, 20, 11, 1311-1322 Chemistry & biology, 20, 11, 1311-1322 Chemistry and Biology, 20, 11, 1311-1322 2013/11 英語 公開
Kawamoto Y, Bando T, Kamada F, Li Y, Hashiya K, Maeshima K, Sugiyama H Kawamoto Y, Bando T, Kamada F, Li Y, Hashiya K, Maeshima K, Sugiyama H Y. Kawamoto; T. Bando; F. Kamada; Y. Li; K. Hashiya; K. Maeshima; H. Sugiyama Development of a new method for synthesis of tandem hairpin pyrrole-imidazole polyamide probes targeting human telomeres. Development of a new method for synthesis of tandem hairpin pyrrole-imidazole polyamide probes targeting human telomeres. Development of a new method for synthesis of tandem hairpin pyrrole-imidazole polyamide probes targeting human telomeres Journal of the American Chemical Society, 135, 44, 16468-16477 Journal of the American Chemical Society, 135, 44, 16468-16477 Journal of the American Chemical Society, 135, 44, 16468-16477 2013/11 英語 公開
Masuda S, Wu J, Hishida T, Pandian GN, Sugiyama H, Izpisua Belmonte JC Masuda S, Wu J, Hishida T, Pandian GN, Sugiyama H, Izpisua Belmonte JC S. Masuda; J. Wu; T. Hishida; G.N. Pandian; H. Sugiyama; J.C. Izpisua Belmonte Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach. Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach. Chemically induced pluripotent stem cells (CiPSCs): A transgene-free approach Journal of molecular cell biology, 5, 5, 354-355 Journal of molecular cell biology, 5, 5, 354-355 Journal of Molecular Cell Biology, 5, 5, 354-355 2013/10 英語 公開
Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Sugiyama H Rajendran A, Endo M, Hidaka K, Tran PL, Mergny JL, Sugiyama H A. Rajendran; M. Endo; K. Hidaka; P. Lan Thao Tran; J.-L. Mergny; H. Sugiyama Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame. Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame. Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame Nucleic acids research, 41, 18, 8738-8747 Nucleic acids research, 41, 18, 8738-8747 Nucleic Acids Research, 41, 18, 8738-8747 2013/10 英語 公開
Han YW, Kashiwazaki G, Morinaga H, Matsumoto T, Hashiya K, Bando T, Harada Y, Sugiyama H Han YW, Kashiwazaki G, Morinaga H, Matsumoto T, Hashiya K, Bando T, Harada Y, Sugiyama H Y.-W. Han; G. Kashiwazaki; H. Morinaga; T. Matsumoto; K. Hashiya; T. Bando; Y. Harada; H. Sugiyama Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5′-GCGC-3′ Bioorganic & medicinal chemistry, 21, 17, 5436-5441 Bioorganic & medicinal chemistry, 21, 17, 5436-5441 Bioorganic and Medicinal Chemistry, 21, 17, 5436-5441 2013/09 英語 公開
Yatsunyk LA, Piétrement O, Albrecht D, Tran PL, Renčiuk D, Sugiyama H, Arbona JM, Aimé JP, Mergny JL Yatsunyk LA, Piétrement O, Albrecht D, Tran PL, Renčiuk D, Sugiyama H, Arbona JM, Aimé JP, Mergny JL L.A. Yatsunyk; O. Piétrement; D. Albrecht; P.L.T. Tran; D. Renčiuk; H. Sugiyama; J.-M. Arbona; J.-P. Aimé; J.-L. Mergny Guided assembly of tetramolecular G-quadruplexes. Guided assembly of tetramolecular G-quadruplexes. Guided assembly of tetramolecular G-quadruplexes ACS nano, 7, 7, 5701-5710 ACS nano, 7, 7, 5701-5710 ACS Nano, 7, 7, 5701-5710 2013/07 英語 公開
Saha A, Pandian GN, Sato S, Taniguchi J, Hashiya K, Bando T, Sugiyama H Saha A, Pandian GN, Sato S, Taniguchi J, Hashiya K, Bando T, Sugiyama H A. Saha; G.N. Pandian; S. Sato; J. Taniguchi; K. Hashiya; T. Bando; H. Sugiyama Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity. Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity. Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity Bioorganic & medicinal chemistry, 21, 14, 4201-4209 Bioorganic & medicinal chemistry, 21, 14, 4201-4209 Bioorganic and Medicinal Chemistry, 21, 14, 4201-4209 2013/07 英語 公開
Kunisada M, Masaki T, Ono R, Morinaga H, Nakano E, Yogianti F, Okunishi K, Sugiyama H, Nishigori C Kunisada M, Masaki T, Ono R, Morinaga H, Nakano E, Yogianti F, Okunishi K, Sugiyama H, Nishigori C M. Kunisada; T. Masaki; R. Ono; H. Morinaga; E. Nakano; F. Yogianti; K. Okunishi; H. Sugiyama; C. Nishigori Hydrochlorothiazide enhances UVA-induced DNA damage. Hydrochlorothiazide enhances UVA-induced DNA damage. Hydrochlorothiazide enhances UVA-induced DNA damage Photochemistry and photobiology, 89, 3, 649-654 Photochemistry and photobiology, 89, 3, 649-654 Photochemistry and Photobiology, 89, 3, 649-654 2013/05 英語 公開
Endo M, Yamamoto S, Tatsumi K, Emura T, Hidaka K, Sugiyama H Endo M, Yamamoto S, Tatsumi K, Emura T, Hidaka K, Sugiyama H M. Endo; S. Yamamoto; K. Tatsumi; T. Emura; K. Hidaka; H. Sugiyama RNA-templated DNA origami structures. RNA-templated DNA origami structures. RNA-templated DNA origami structures Chemical communications (Cambridge, England), 49, 28, 2879-2881 Chemical communications (Cambridge, England), 49, 28, 2879-2881 Chemical Communications, 49, 28, 2879-2881 2013/04 英語 公開
Morinaga H, Takenaka T, Hashiya F, Kizaki S, Hashiya K, Bando T, Sugiyama H Morinaga H, Takenaka T, Hashiya F, Kizaki S, Hashiya K, Bando T, Sugiyama H H. Morinaga; T. Takenaka; F. Hashiya; S. Kizaki; K. Hashiya; T. Bando; H. Sugiyama Sequence-specific electron injection into DNA from an intermolecular electron donor. Sequence-specific electron injection into DNA from an intermolecular electron donor. Sequence-specific electron injection into DNA from an intermolecular electron donor Nucleic acids research, 41, 8, 4724-4728 Nucleic acids research, 41, 8, 4724-4728 Nucleic Acids Research, 41, 8, 4724-4728 2013/04 英語 公開
Koirala D, Ghimire C, Bohrer C, Sannohe Y, Sugiyama H, Mao H Koirala D, Ghimire C, Bohrer C, Sannohe Y, Sugiyama H, Mao H D. Koirala; C. Ghimire; C. Bohrer; Y. Sannohe; H. Sugiyama; H. Mao Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences. Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences. Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences Journal of the American Chemical Society, 135, 6, 2235-2241 Journal of the American Chemical Society, 135, 6, 2235-2241 Journal of the American Chemical Society, 135, 6, 2235-2241 2013/02 英語 公開
Vaijayanthi T, Bando T, Hashiya K, Pandian GN, Sugiyama H Vaijayanthi T, Bando T, Hashiya K, Pandian GN, Sugiyama H T. Vaijayanthi; T. Bando; K. Hashiya; G.N. Pandian; H. Sugiyama Design of a new fluorescent probe: pyrrole/imidazole hairpin polyamides with pyrene conjugation at their γ-turn. Design of a new fluorescent probe: pyrrole/imidazole hairpin polyamides with pyrene conjugation at their γ-turn. Design of a new fluorescent probe: Pyrrole/imidazole hairpin polyamides with pyrene conjugation at their γ-turn Bioorganic & medicinal chemistry, 21, 4, 852-855 Bioorganic & medicinal chemistry, 21, 4, 852-855 Bioorganic and Medicinal Chemistry, 21, 4, 852-855 2013/02 英語 公開
Rajendran A, Endo M, Hidaka K, Sugiyama H Rajendran A, Endo M, Hidaka K, Sugiyama H A. Rajendran; M. Endo; K. Hidaka; H. Sugiyama Direct and real-time observation of rotary movement of a DNA nanomechanical device. Direct and real-time observation of rotary movement of a DNA nanomechanical device. Direct and real-time observation of rotary movement of a DNA nanomechanical device Journal of the American Chemical Society, 135, 3, 1117-1123 Journal of the American Chemical Society, 135, 3, 1117-1123 Journal of the American Chemical Society, 135, 3, 1117-1123 2013/01 英語 公開
Morinaga H, Kizaki S, Takenaka T, Kanesato S, Sannohe Y, Tashiro R, Sugiyama H Morinaga H, Kizaki S, Takenaka T, Kanesato S, Sannohe Y, Tashiro R, Sugiyama H H. Morinaga; S. Kizaki; T. Takenaka; S. Kanesato; Y. Sannohe; R. Tashiro; H. Sugiyama Photoreactivities of 5-bromouracil-containing RNAs. Photoreactivities of 5-bromouracil-containing RNAs. Photoreactivities of 5-Bromouracil-containing RNAs Bioorganic & medicinal chemistry, 21, 2, 466-469 Bioorganic & medicinal chemistry, 21, 2, 466-469 Bioorganic and Medicinal Chemistry, 21, 2, 466-469 2013/01 英語 公開
Miyahara T, Nakatsuji H, Sugiyama H Miyahara T, Nakatsuji H, Sugiyama H T. Miyahara; H. Nakatsuji; H. Sugiyama Helical structure and circular dichroism spectra of DNA: a theoretical study. Helical structure and circular dichroism spectra of DNA: a theoretical study. Helical structure and circular dichroism spectra of DNA: A theoretical study The journal of physical chemistry. A, 117, 1, 42-55 The journal of physical chemistry. A, 117, 1, 42-55 Journal of Physical Chemistry A, 117, 1, 42-55 2013/01 英語 公開
Rajendran A, Endo M, Hidaka K, Sugiyama H Rajendran A, Endo M, Hidaka K, Sugiyama H A. Rajendran; M. Endo; K. Hidaka; H. Sugiyama Control of the two-dimensional crystallization of DNA origami with various loop arrangements. Control of the two-dimensional crystallization of DNA origami with various loop arrangements. Control of the two-dimensional crystallization of DNA origami with various loop arrangements Chemical communications (Cambridge, England), 49, 7, 686-688 Chemical communications (Cambridge, England), 49, 7, 686-688 Chemical Communications, 49, 7, 686-688 2013/01 英語 公開
Liang J, Wu YL, Chen BJ, Zhang W, Tanaka Y, Sugiyama H Liang J, Wu YL, Chen BJ, Zhang W, Tanaka Y, Sugiyama H J. Liang; Y.-L. Wu; B.-J. Chen; W. Zhang; Y. Tanaka; H. Sugiyama The C-kit receptor-mediated signal transduction and tumor-related diseases. The C-kit receptor-mediated signal transduction and tumor-related diseases. The C-Kit receptor-mediated signal transduction and tumor-related diseases International journal of biological sciences, 9, 5, 435-443 International journal of biological sciences, 9, 5, 435-443 International Journal of Biological Sciences, 9, 5, 435-443 2013 英語 公開
Iguchi A, Fukuda N, Takahashi T, Watanabe T, Matsuda H, Nagase H, Bando T, Sugiyama H, Shimizu K Iguchi A, Fukuda N, Takahashi T, Watanabe T, Matsuda H, Nagase H, Bando T, Sugiyama H, Shimizu K A. Iguchi; N. Fukuda; T. Takahashi; T. Watanabe; H. Matsuda; H. Nagase; T. Bando; H. Sugiyama; K. Shimizu RNA binding properties of novel gene silencing pyrrole-imidazole polyamides. RNA binding properties of novel gene silencing pyrrole-imidazole polyamides. RNA binding properties of novel gene silencing pyrrole-imidazole polyamides Biological & pharmaceutical bulletin, 36, 7, 1152-1158 Biological & pharmaceutical bulletin, 36, 7, 1152-1158 Biological and Pharmaceutical Bulletin, 36, 7, 1152-1158 2013 英語 公開
Yang Y, Endo M, Hidaka K, Sugiyama H Yang Y, Endo M, Hidaka K, Sugiyama H Y. Yang; M. Endo; K. Hidaka; H. Sugiyama Photo-controllable DNA origami nanostructures assembling into predesigned multiorientational patterns. Photo-controllable DNA origami nanostructures assembling into predesigned multiorientational patterns. Photo-controllable DNA origami nanostructures assembling into predesigned multiorientational patterns Journal of the American Chemical Society, 134, 51, 20645-20653 Journal of the American Chemical Society, 134, 51, 20645-20653 Journal of the American Chemical Society, 134, 51, 20645-20653 2012/12 英語 公開
Han YW, Matsumoto T, Yokota H, Kashiwazaki G, Morinaga H, Hashiya K, Bando T, Harada Y, Sugiyama H Han YW, Matsumoto T, Yokota H, Kashiwazaki G, Morinaga H, Hashiya K, Bando T, Harada Y, Sugiyama H Y.-W. Han; T. Matsumoto; H. Yokota; G. Kashiwazaki; H. Morinaga; K. Hashiya; T. Bando; Y. Harada; H. Sugiyama Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants. Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants. Binding of hairpin pyrrole and imidazole polyamides to DNA: Relationship between torsion angle and association rate constants Nucleic acids research, 40, 22, 11510-11517 Nucleic acids research, 40, 22, 11510-11517 Nucleic Acids Research, 40, 22, 11510-11517 2012/12 英語 公開
Pandian GN, Sugiyama H Pandian GN, Sugiyama H G.N. Pandian; H. Sugiyama Strategies to modulate heritable epigenetic defects in cellular machinery: lessons from nature. Strategies to modulate heritable epigenetic defects in cellular machinery: lessons from nature. Strategies to modulate heritable epigenetic defects in cellular machinery: Lessons from nature Pharmaceuticals (Basel, Switzerland), 6, 1, 1-24 Pharmaceuticals (Basel, Switzerland), 6, 1, 1-24 Pharmaceuticals, 6, 1, 1-24 2012/12 英語 公開
Park S, Sugiyama H Park S, Sugiyama H S. Park; H. Sugiyama DNA as a chiral scaffold for asymmetric synthesis. DNA as a chiral scaffold for asymmetric synthesis. DNA as a chiral scaffold for asymmetric synthesis Molecules (Basel, Switzerland), 17, 11, 12792-12803 Molecules (Basel, Switzerland), 17, 11, 12792-12803 Molecules, 17, 11, 12792-12803 2012/10 英語 公開
Vaijayanthi T, Bando T, Pandian GN, Sugiyama H Vaijayanthi T, Bando T, Pandian GN, Sugiyama H T. Vaijayanthi; T. Bando; G.N. Pandian; H. Sugiyama Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes. Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes. Progress and Prospects of Pyrrole-Imidazole Polyamide-Fluorophore Conjugates as Sequence-Selective DNA Probes Chembiochem : a European journal of chemical biology, 13, 15, 2170-2185 Chembiochem : a European journal of chemical biology, 13, 15, 2170-2185 ChemBioChem, 13, 15, 2170-2185 2012/10 英語 公開
Park S, Ikehata K, Watabe R, Hidaka Y, Rajendran A, Sugiyama H Park S, Ikehata K, Watabe R, Hidaka Y, Rajendran A, Sugiyama H S. Park; K. Ikehata; R. Watabe; Y. Hidaka; A. Rajendran; H. Sugiyama Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations. Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations. Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations Chemical communications (Cambridge, England), 48, 84, 10398-10400 Chemical communications (Cambridge, England), 48, 84, 10398-10400 Chemical Communications, 48, 84, 10398-10400 2012/10 英語 公開
Endo M, Yang Y, Suzuki Y, Hidaka K, Sugiyama H Endo M, Yang Y, Suzuki Y, Hidaka K, Sugiyama H M. Endo; Y. Yang; Y. Suzuki; K. Hidaka; H. Sugiyama Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure. Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure. Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure Angewandte Chemie (International ed. in English), 51, 42, 10518-10522 Angewandte Chemie (International ed. in English), 51, 42, 10518-10522 Angewandte Chemie - International Edition, 51, 42, 10518-10522 2012/10 英語 公開
Endo M, Tatsumi K, Terushima K, Katsuda Y, Hidaka K, Harada Y, Sugiyama H Endo M, Tatsumi K, Terushima K, Katsuda Y, Hidaka K, Harada Y, Sugiyama H M. Endo; K. Tatsumi; K. Terushima; Y. Katsuda; K. Hidaka; Y. Harada; H. Sugiyama Direct visualization of the movement of a single T7 RNA polymerase and transcription on a DNA nanostructure. Direct visualization of the movement of a single T7 RNA polymerase and transcription on a DNA nanostructure. Direct visualization of the movement of a single T7 RNA polymerase and transcription on a DNA nanostructure Angewandte Chemie (International ed. in English), 51, 35, 8778-8782 Angewandte Chemie (International ed. in English), 51, 35, 8778-8782 Angewandte Chemie - International Edition, 51, 35, 8778-8782 2012/08 英語 公開
Takagaki T, Bando T, Sugiyama H Takagaki T, Bando T, Sugiyama H T. Takagaki; T. Bando; H. Sugiyama Synthesis of pyrrole-imidazole polyamide seco-1-chloromethyl-5-hydroxy-1,2-dihydro-3h-benz[e]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence. Synthesis of pyrrole-imidazole polyamide seco-1-chloromethyl-5-hydroxy-1,2-dihydro-3h-benz[e]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence. Synthesis of pyrrole-imidazole polyamide seco -1-chloromethyl-5-hydroxy-1, 2-dihydro-3 H -benz[ e ]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence Journal of the American Chemical Society, 134, 31, 13074-13081 Journal of the American Chemical Society, 134, 31, 13074-13081 Journal of the American Chemical Society, 134, 31, 13074-13081 2012/08 英語 公開
Pandian GN, Nakano Y, Sato S, Morinaga H, Bando T, Nagase H, Sugiyama H Pandian GN, Nakano Y, Sato S, Morinaga H, Bando T, Nagase H, Sugiyama H G.N. Pandian; Y. Nakano; S. Sato; H. Morinaga; T. Bando; H. Nagase; H. Sugiyama A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts. A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts. A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts Scientific reports, 2, 544 Scientific reports, 2, 544 Scientific Reports, 2, 544 2012/07/30 英語 公開
Mohri K, Nishikawa M, Takahashi N, Shiomi T, Matsuoka N, Ogawa K, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y Mohri K, Nishikawa M, Takahashi N, Shiomi T, Matsuoka N, Ogawa K, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y K. Mohri; M. Nishikawa; N. Takahashi; T. Shiomi; N. Matsuoka; K. Ogawa; M. Endo; K. Hidaka; H. Sugiyama; Y. Takahashi; Y. Takakura Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory CpG motifs to immune cells. Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory CpG motifs to immune cells. Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory cpg motifs to immune cells ACS nano, 6, 7, 5931-5940 ACS nano, 6, 7, 5931-5940 ACS Nano, 6, 7, 5931-5940 2012/07 英語 公開
Zhang HF, Wu YL, Jiang SK, Wang P, Sugiyama H, Chen XL, Zhang W, Ji YJ, Guo CX Zhang HF, Wu YL, Jiang SK, Wang P, Sugiyama H, Chen XL, Zhang W, Ji YJ, Guo CX H.-F. Zhang; Y.-L. Wu; S.-K. Jiang; P. Wang; H. Sugiyama; X.-L. Chen; W. Zhang; Y.-J. Ji; C.-X. Guo Recognition by nonaromatic and stereochemical subunit-containing polyamides of the four Watson-Crick base pairs in the DNA minor groove. Recognition by nonaromatic and stereochemical subunit-containing polyamides of the four Watson-Crick base pairs in the DNA minor groove. Recognition by Nonaromatic and Stereochemical Subunit-Containing Polyamides of the Four Watson-Crick Base Pairs in the DNA Minor Groove Chembiochem : a European journal of chemical biology, 13, 9, 1366-1374 Chembiochem : a European journal of chemical biology, 13, 9, 1366-1374 ChemBioChem, 13, 9, 1366-1374 2012/06 英語 公開
Pandian GN, Sugiyama H Pandian GN, Sugiyama H G.N. Pandian; H. Sugiyama Programmable genetic switches to control transcriptional machinery of pluripotency. Programmable genetic switches to control transcriptional machinery of pluripotency. Programmable genetic switches to control transcriptional machinery of pluripotency Biotechnology journal, 7, 6, 798-809 Biotechnology journal, 7, 6, 798-809 Biotechnology Journal, 7, 6, 798-809 2012/06 英語 公開
Pandian GN, Ohtsuki A, Bando T, Sato S, Hashiya K, Sugiyama H Pandian GN, Ohtsuki A, Bando T, Sato S, Hashiya K, Sugiyama H G.N. Pandian; A. Ohtsuki; T. Bando; S. Sato; K. Hashiya; H. Sugiyama Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes. Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes. Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes Bioorganic & medicinal chemistry, 20, 8, 2656-2660 Bioorganic & medicinal chemistry, 20, 8, 2656-2660 Bioorganic and Medicinal Chemistry, 20, 8, 2656-2660 2012/04 英語 公開
Rajendran A, Endo M, Sugiyama H Rajendran A, Endo M, Sugiyama H A. Rajendran; M. Endo; H. Sugiyama DNA origami: synthesis and self-assembly. DNA origami: synthesis and self-assembly. DNA origami: synthesis and self-assembly. Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 48, Unit 12.9.1-18 Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 48, Unit 12.9.1-18 Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 48, Unit 12.9.1-18 2012/03 英語 公開
Sannohe Y, Sugiyama H Sannohe Y, Sugiyama H Y. Sannohe; H. Sugiyama Single strand DNA catenane synthesis using the formation of G-quadruplex structure. Single strand DNA catenane synthesis using the formation of G-quadruplex structure. Single strand DNA catenane synthesis using the formation of G-quadruplex structure Bioorganic & medicinal chemistry, 20, 6, 2030-2034 Bioorganic & medicinal chemistry, 20, 6, 2030-2034 Bioorganic and Medicinal Chemistry, 20, 6, 2030-2034 2012/03 英語 公開
Yoshidome T, Endo M, Kashiwazaki G, Hidaka K, Bando T, Sugiyama H Yoshidome T, Endo M, Kashiwazaki G, Hidaka K, Bando T, Sugiyama H T. Yoshidome; M. Endo; G. Kashiwazaki; K. Hidaka; T. Bando; H. Sugiyama Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold. Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold. Sequence-selective single-molecule alkylation with a pyrrole-imidazole polyamide visualized in a DNA nanoscaffold Journal of the American Chemical Society, 134, 10, 4654-4660 Journal of the American Chemical Society, 134, 10, 4654-4660 Journal of the American Chemical Society, 134, 10, 4654-4660 2012/03 英語 公開
Kashiwazaki G, Bando T, Yoshidome T, Masui S, Takagaki T, Hashiya K, Pandian GN, Yasuoka J, Akiyoshi K, Sugiyama H Kashiwazaki G, Bando T, Yoshidome T, Masui S, Takagaki T, Hashiya K, Pandian GN, Yasuoka J, Akiyoshi K, Sugiyama H G. Kashiwazaki; T. Bando; T. Yoshidome; S. Masui; T. Takagaki; K. Hashiya; G.N. Pandian; J. Yasuoka; K. Akiyoshi; H. Sugiyama Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates. Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates. Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole- N -methylimidazole polyamide conjugates Journal of medicinal chemistry, 55, 5, 2057-2066 Journal of medicinal chemistry, 55, 5, 2057-2066 Journal of Medicinal Chemistry, 55, 5, 2057-2066 2012/03 英語 公開
Nakata E, Liew FF, Uwatoko C, Kiyonaka S, Mori Y, Katsuda Y, Endo M, Sugiyama H, Morii T Nakata E, Liew FF, Uwatoko C, Kiyonaka S, Mori Y, Katsuda Y, Endo M, Sugiyama H, Morii T E. Nakata; F.F. Liew; C. Uwatoko; S. Kiyonaka; Y. Mori; Y. Katsuda; M. Endo; H. Sugiyama; T. Morii Zinc-finger proteins for site-specific protein positioning on DNA-origami structures. Zinc-finger proteins for site-specific protein positioning on DNA-origami structures. Zinc-finger proteins for site-specific protein positioning on DNA-origami structures Angewandte Chemie (International ed. in English), 51, 10, 2421-2424 Angewandte Chemie (International ed. in English), 51, 10, 2421-2424 Angewandte Chemie - International Edition, 51, 10, 2421-2424 2012/03 英語 公開
Endo M, Miyazaki R, Emura T, Hidaka K, Sugiyama H Endo M, Miyazaki R, Emura T, Hidaka K, Sugiyama H M. Endo; R. Miyazaki; T. Emura; K. Hidaka; H. Sugiyama Transcription regulation system mediated by mechanical operation of a DNA nanostructure. Transcription regulation system mediated by mechanical operation of a DNA nanostructure. Transcription regulation system mediated by mechanical operation of a DNA nanostructure Journal of the American Chemical Society, 134, 6, 2852-2855 Journal of the American Chemical Society, 134, 6, 2852-2855 Journal of the American Chemical Society, 134, 6, 2852-2855 2012/02 英語 公開
Koirala D, Mashimo T, Sannohe Y, Yu Z, Mao H, Sugiyama H Koirala D, Mashimo T, Sannohe Y, Yu Z, Mao H, Sugiyama H D. Koirala; T. Mashimo; Y. Sannohe; Z. Yu; H. Mao; H. Sugiyama Intramolecular folding in three tandem guanine repeats of human telomeric DNA. Intramolecular folding in three tandem guanine repeats of human telomeric DNA. Intramolecular folding in three tandem guanine repeats of human telomeric DNA Chemical communications (Cambridge, England), 48, 14, 2006-2008 Chemical communications (Cambridge, England), 48, 14, 2006-2008 Chemical Communications, 48, 14, 2006-2008 2012/02 英語 公開
Wickham SF, Bath J, Katsuda Y, Endo M, Hidaka K, Sugiyama H, Turberfield AJ Wickham SF, Bath J, Katsuda Y, Endo M, Hidaka K, Sugiyama H, Turberfield AJ S.F.J. Wickham; J. Bath; Y. Katsuda; M. Endo; K. Hidaka; H. Sugiyama; A.J. Turberfield A DNA-based molecular motor that can navigate a network of tracks. A DNA-based molecular motor that can navigate a network of tracks. A DNA-based molecular motor that can navigate a network of tracks Nature nanotechnology, 7, 3, 169-173 Nature nanotechnology, 7, 3, 169-173 Nature Nanotechnology, 7, 3, 169-173 2012/01 英語 公開
Mulholland N, Xu Y, Sugiyama H, Zhao K Mulholland N, Xu Y, Sugiyama H, Zhao K N. Mulholland; Y. Xu; H. Sugiyama; K. Zhao SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome. SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome. SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome Cell & bioscience, 2, 1, 3 Cell & bioscience, 2, 1, 3 Cell and Bioscience, 2, 1, 3 2012/01 英語 公開
Rajendran A, Endo M, Sugiyama H Rajendran A, Endo M, Sugiyama H A. Rajendran; M. Endo; H. Sugiyama Single-molecule analysis using DNA origami. Single-molecule analysis using DNA origami. Single-molecule analysis using DNA origami Angewandte Chemie (International ed. in English), 51, 4, 874-890 Angewandte Chemie (International ed. in English), 51, 4, 874-890 Angewandte Chemie - International Edition, 51, 4, 874-890 2012/01 英語 公開
Zhang W, Jiang SK, Wu YL, Guo CX, Zhang HF, Sugiyama H, Chen XL Zhang W, Jiang SK, Wu YL, Guo CX, Zhang HF, Sugiyama H, Chen XL W. Zhang; S.-K. Jiang; Y.-L. Wu; C.-X. Guo; H.-F. Zhang; H. Sugiyama; X.-L. Chen Discrimination between T/A and A/T base pairs of pyrrole-imidazole polyamides substituted with chiral β-hydroxy-γ-aminobutyric acid/β-alanine pairs. Discrimination between T/A and A/T base pairs of pyrrole-imidazole polyamides substituted with chiral β-hydroxy-γ-aminobutyric acid/β-alanine pairs. Discrimination between T/A and A/T Base Pairs of Pyrrole-Imidazole Polyamides Substituted with Chiral β-Hydroxy-γ-Aminobutyric Acid/β-Alanine Pairs Chembiochem : a European journal of chemical biology, 13, 1, 47-50 Chembiochem : a European journal of chemical biology, 13, 1, 47-50 ChemBioChem, 13, 1, 47-50 2012/01 英語 公開
Rajendran A, Endo M, Sugiyama H Rajendran A, Endo M, Sugiyama H A. Rajendran; M. Endo; H. Sugiyama Structural and functional analysis of proteins by high-speed atomic force microscopy. Structural and functional analysis of proteins by high-speed atomic force microscopy. Structural and functional analysis of proteins by high-speed atomic force microscopy Advances in protein chemistry and structural biology, 87, 5-55 Advances in protein chemistry and structural biology, 87, 5-55 Advances in Protein Chemistry and Structural Biology, 87, 5-55 2012 英語 公開
Pandian GN, Shinohara K, Ohtsuki A, Nakano Y, Masafumi M, Bando T, Nagase H, Yamada Y, Watanabe A, Terada N, Sato S, Morinaga H, Sugiyama H Pandian GN, Shinohara K, Ohtsuki A, Nakano Y, Masafumi M, Bando T, Nagase H, Yamada Y, Watanabe A, Terada N, Sato S, Morinaga H, Sugiyama H G.N. Pandian; K.-I. Shinohara; A. Ohtsuki; Y. Nakano; M. Masafumi; T. Bando; H. Nagase; Y. Yamada; A. Watanabe; N. Terada; S. Sato; H. Morinaga; H. Sugiyama Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts. Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts. Synthetic small molecules for epigenetic activation of pluripotency genes in mouse embryonic fibroblasts Chembiochem : a European journal of chemical biology, 12, 18, 2822-2828 Chembiochem : a European journal of chemical biology, 12, 18, 2822-2828 ChemBioChem, 12, 18, 2822-2828 2011/12 英語 公開
Yasuda A, Noguchi K, Minoshima M, Kashiwazaki G, Kanda T, Katayama K, Mitsuhashi J, Bando T, Sugiyama H, Sugimoto Y Yasuda A, Noguchi K, Minoshima M, Kashiwazaki G, Kanda T, Katayama K, Mitsuhashi J, Bando T, Sugiyama H, Sugimoto Y A. Yasuda; K. Noguchi; M. Minoshima; G. Kashiwazaki; T. Kanda; K. Katayama; J. Mitsuhashi; T. Bando; H. Sugiyama; Y. Sugimoto DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization. DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization. DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization Cancer science, 102, 12, 2221-2230 Cancer science, 102, 12, 2221-2230 Cancer Science, 102, 12, 2221-2230 2011/12 英語 公開
Morinaga H, Bando T, Takagaki T, Yamamoto M, Hashiya K, Sugiyama H Morinaga H, Bando T, Takagaki T, Yamamoto M, Hashiya K, Sugiyama H H. Morinaga; T. Bando; T. Takagaki; M. Yamamoto; K. Hashiya Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove. Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove. Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove Journal of the American Chemical Society, 133, 46, 18924-18930 Journal of the American Chemical Society, 133, 46, 18924-18930 Journal of the American Chemical Society, 133, 46, 18924-18930 2011/11 英語 公開
Takagaki T, Bando T, Kitano M, Hashiya K, Kashiwazaki G, Sugiyama H Takagaki T, Bando T, Kitano M, Hashiya K, Kashiwazaki G, Sugiyama H T. Takagaki; T. Bando; M. Kitano; K. Hashiya; G. Kashiwazaki; H. Sugiyama Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation. Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation. Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation Bioorganic & medicinal chemistry, 19, 19, 5896-5902 Bioorganic & medicinal chemistry, 19, 19, 5896-5902 Bioorganic and Medicinal Chemistry, 19, 19, 5896-5902 2011/10 英語 公開
Endo M, Yang Y, Emura T, Hidaka K, Sugiyama H Endo M, Yang Y, Emura T, Hidaka K, Sugiyama H M. Endo; Y. Yang; T. Emura; K. Hidaka; H. Sugiyama Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold. Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold. Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold Chemical communications (Cambridge, England), 47, 38, 10743-10745 Chemical communications (Cambridge, England), 47, 38, 10743-10745 Chemical Communications, 47, 38, 10743-10745 2011/10 英語 公開
Rajendran A, Endo M, Katsuda Y, Hidaka K, Sugiyama H Rajendran A, Endo M, Katsuda Y, Hidaka K, Sugiyama H A. Rajendran; M. Endo; Y. Katsuda; K. Hidaka; H. Sugiyama Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly. Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly. Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly Journal of the American Chemical Society, 133, 37, 14488-14491 Journal of the American Chemical Society, 133, 37, 14488-14491 Journal of the American Chemical Society, 133, 37, 14488-14491 2011/09 英語 公開
Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao H Koirala D, Dhakal S, Ashbridge B, Sannohe Y, Rodriguez R, Sugiyama H, Balasubramanian S, Mao H D. Koirala; S. Dhakal; B. Ashbridge; Y. Sannohe; R. Rodriguez; H. Sugiyama; S. Balasubramanian; H. Mao A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands Nature chemistry, 3, 10, 782-787 Nature chemistry, 3, 10, 782-787 Nature Chemistry, 3, 10, 782-787 2011/08 英語 公開
Endo M, Sugiyama H Endo M, Sugiyama H M. Endo; H. Sugiyama Recent progress in DNA origami technology. Recent progress in DNA origami technology. Recent progress in DNA origami technology. Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 45, Unit12.8 Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 45, Unit12.8 Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 12, SUPPL. 45, Unit12.8 2011/06 英語 公開
Endo M, Hidaka K, Sugiyama H Endo M, Hidaka K, Sugiyama H M. Endo; K. Hidaka; H. Sugiyama Direct AFM observation of an opening event of a DNA cuboid constructed via a prism structure. Direct AFM observation of an opening event of a DNA cuboid constructed via a prism structure. Direct AFM observation of an opening event of a DNA cuboid constructed via a prism structure Organic & biomolecular chemistry, 9, 7, 2075-2077 Organic & biomolecular chemistry, 9, 7, 2075-2077 Organic and Biomolecular Chemistry, 9, 7, 2075-2077 2011/04 英語 公開
Wickham SF, Endo M, Katsuda Y, Hidaka K, Bath J, Sugiyama H, Turberfield AJ Wickham SF, Endo M, Katsuda Y, Hidaka K, Bath J, Sugiyama H, Turberfield AJ S.F.J. Wickham; M. Endo; Y. Katsuda; K. Hidaka; J. Bath; H. Sugiyama; A.J. Turberfield Direct observation of stepwise movement of a synthetic molecular transporter. Direct observation of stepwise movement of a synthetic molecular transporter. Direct observation of stepwise movement of a synthetic molecular transporter Nature nanotechnology, 6, 3, 166-169 Nature nanotechnology, 6, 3, 166-169 Nature Nanotechnology, 6, 3, 166-169 2011/03 英語 公開
Endo M, Sugita T, Rajendran A, Katsuda Y, Emura T, Hidaka K, Sugiyama H Endo M, Sugita T, Rajendran A, Katsuda Y, Emura T, Hidaka K, Sugiyama H M. Endo; T. Sugita; A. Rajendran; Y. Katsuda; T. Emura; K. Hidaka; H. Sugiyama Two-dimensional DNA origami assemblies using a four-way connector. Two-dimensional DNA origami assemblies using a four-way connector. Two-dimensional DNA origami assemblies using a four-way connector Chemical communications (Cambridge, England), 47, 11, 3213-3215 Chemical communications (Cambridge, England), 47, 11, 3213-3215 Chemical Communications, 47, 11, 3213-3215 2011/03 英語 公開
Park S, Bando T, Shinohara K, Nishijima S, Sugiyama H Park S, Bando T, Shinohara K, Nishijima S, Sugiyama H S. Park; T. Bando; K.-I. Shinohara; S. Nishijima; H. Sugiyama Photocontrollable sequence-specific DNA alkylation by a pyrrole-imidazole polyamide seco-CBI conjugate. Photocontrollable sequence-specific DNA alkylation by a pyrrole-imidazole polyamide seco-CBI conjugate. Photocontrollable sequence-specific DNA alkylation by a pyrrole-imidazole polyamide seco-CBI conjugate Bioconjugate chemistry, 22, 2, 120-124 Bioconjugate chemistry, 22, 2, 120-124 Bioconjugate Chemistry, 22, 2, 120-124 2011/02 英語 公開
Rajendran A, Endo M, Katsuda Y, Hidaka K, Sugiyama H Rajendran A, Endo M, Katsuda Y, Hidaka K, Sugiyama H A. Rajendran; M. Endo; Y. Katsuda; K. Hidaka; H. Sugiyama Programmed two-dimensional self-assembly of multiple DNA origami jigsaw pieces. Programmed two-dimensional self-assembly of multiple DNA origami jigsaw pieces. Programmed two-dimensional self-assembly of multiple DNA origami jigsaw pieces ACS nano, 5, 1, 665-671 ACS nano, 5, 1, 665-671 ACS Nano, 5, 1, 665-671 2011/01 英語 公開
Matsuda H, Fukuda N, Ueno T, Katakawa M, Wang X, Watanabe T, Matsui S, Aoyama T, Saito K, Bando T, Matsumoto Y, Nagase H, Matsumoto K, Sugiyama H Matsuda H, Fukuda N, Ueno T, Katakawa M, Wang X, Watanabe T, Matsui S, Aoyama T, Saito K, Bando T, Matsumoto Y, Nagase H, Matsumoto K, Sugiyama H H. Matsuda; N. Fukuda; T. Ueno; M. Katakawa; X. Wang; T. Watanabe; S.-I. Matsui; T. Aoyama; K. Saito; T. Bando; Y. Matsumoto; H. Nagase; K. Matsumoto; H. Sugiyama Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter. Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter. Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-Β1 promoter Kidney international, 79, 1, 46-56 Kidney international, 79, 1, 46-56 Kidney International, 79, 1, 46-56 2011/01 英語 公開
M. Endo; H. Sugiyama M. Endo; H. Sugiyama M. Endo; H. Sugiyama DNA origami-based construction of meso-scale multi-dimensional architects and expression of the functionality in the designed DNA nanospace DNA origami-based construction of meso-scale multi-dimensional architects and expression of the functionality in the designed DNA nanospace DNA origami-based construction of meso-scale multi-dimensional architects and expression of the functionality in the designed DNA nanospace Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 69, 12, 1352-1362 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 69, 12, 1352-1362 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 69, 12, 1352-1362 2011 日本語 公開
Endo M, Katsuda Y, Hidaka K, Sugiyama H Endo M, Katsuda Y, Hidaka K, Sugiyama H M. Endo; Y. Katsuda; K. Hidaka; H. Sugiyama A versatile DNA nanochip for direct analysis of DNA base-excision repair. A versatile DNA nanochip for direct analysis of DNA base-excision repair. A versatile DNA nanochip for direct analysis of DNA base-excision repair Angewandte Chemie (International ed. in English), 49, 49, 9412-9416 Angewandte Chemie (International ed. in English), 49, 49, 9412-9416 Angewandte Chemie - International Edition, 49, 49, 9412-9416 2010/12 英語 公開
Sannohe Y, Endo M, Katsuda Y, Hidaka K, Sugiyama H Sannohe Y, Endo M, Katsuda Y, Hidaka K, Sugiyama H Y. Sannohe; M. Endo; Y. Katsuda; K. Hidaka; H. Sugiyama Visualization of dynamic conformational switching of the G-quadruplex in a DNA nanostructure. Visualization of dynamic conformational switching of the G-quadruplex in a DNA nanostructure. Visualization of dynamic conformational switching of the G-quadruplex in a DNA nanostructure Journal of the American Chemical Society, 132, 46, 16311-16313 Journal of the American Chemical Society, 132, 46, 16311-16313 Journal of the American Chemical Society, 132, 46, 16311-16313 2010/11 英語 公開
Mashimo T, Yagi H, Sannohe Y, Rajendran A, Sugiyama H Mashimo T, Yagi H, Sannohe Y, Rajendran A, Sugiyama H T. Mashimo; H. Yagi; Y. Sannohe; A. Rajendran; H. Sugiyama Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures. Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures. Folding pathways of human telomeric type-1 and type-2 G-Quadruplex structures Journal of the American Chemical Society, 132, 42, 14910-14918 Journal of the American Chemical Society, 132, 42, 14910-14918 Journal of the American Chemical Society, 132, 42, 14910-14918 2010/10 英語 公開
Tashiro R, Ohtsuki A, Sugiyama H Tashiro R, Ohtsuki A, Sugiyama H R. Tashiro; A. Ohtsuki; H. Sugiyama The distance between donor and acceptor affects the proportion of C1' and C2' oxidation products of DNA in a BrU-containing excess electron transfer system. The distance between donor and acceptor affects the proportion of C1' and C2' oxidation products of DNA in a BrU-containing excess electron transfer system. The distance between donor and acceptor affects the proportion of C1′ and C2′ oxidation products of DNA in a <sup>Br</sup>U-containing excess electron transfer system Journal of the American Chemical Society, 132, 41, 14361-14363 Journal of the American Chemical Society, 132, 41, 14361-14363 Journal of the American Chemical Society, 132, 41, 14361-14363 2010/10 英語 公開
Hori M, Yonekura S, Nohmi T, Gruz P, Sugiyama H, Yonei S, Zhang-Akiyama QM Hori M, Yonekura S, Nohmi T, Gruz P, Sugiyama H, Yonei S, Zhang-Akiyama QM M. Hori; S.-I. Yonekura; T. Nohmi; P. Gruz; H. Sugiyama; S. Yonei; Q.-M. Zhang-Akiyama Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine. Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine. Error-prone translesion DNA synthesis by Escherichia coli DNA polymerase IV (DinB) on templates containing 1,2-dihydro-2-oxoadenine Journal of nucleic acids, 2010, 807579 Journal of nucleic acids, 2010, 807579 Journal of Nucleic Acids, 2010, 807579 2010/09 英語 公開
Tanaka H, Tanaka Y, Minoshima M, Yamaguchi S, Fuse S, Doi T, Kawauchi S, Sugiyama H, Takahashi T Tanaka H, Tanaka Y, Minoshima M, Yamaguchi S, Fuse S, Doi T, Kawauchi S, Sugiyama H, Takahashi T H. Tanaka; Y. Tanaka; M. Minoshima; S. Yamaguchi; S. Fuse; T. Doi; S. Kawauchi; H. Sugiyama; T. Takahashi Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity. Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity. Synthesis of bicyclic enediynes that possess a photosensitive triggering device and exhibit strong DNA cleaving activity Chemical communications (Cambridge, England), 46, 32, 5942-5944 Chemical communications (Cambridge, England), 46, 32, 5942-5944 Chemical Communications, 46, 32, 5942-5944 2010/08 英語 公開
Park S, Sugiyama H Park S, Sugiyama H S. Park; H. Sugiyama DNA-based hybrid catalysts for asymmetric organic synthesis. DNA-based hybrid catalysts for asymmetric organic synthesis. DNA-based hybrid catalysts for asymmetric organic synthesis Angewandte Chemie (International ed. in English), 49, 23, 3870-3878 Angewandte Chemie (International ed. in English), 49, 23, 3870-3878 Angewandte Chemie - International Edition, 49, 23, 3870-3878 2010/05 英語 公開
Endo M, Sugita T, Katsuda Y, Hidaka K, Sugiyama H Endo M, Sugita T, Katsuda Y, Hidaka K, Sugiyama H M. Endo; T. Sugita; Y. Katsuda; K. Hidaka; H. Sugiyama Programmed-assembly system using DNA jigsaw pieces. Programmed-assembly system using DNA jigsaw pieces. Programmed-assembly system using DNA jigsaw pieces Chemistry (Weinheim an der Bergstrasse, Germany), 16, 18, 5362-5368 Chemistry (Weinheim an der Bergstrasse, Germany), 16, 18, 5362-5368 Chemistry - A European Journal, 16, 18, 5362-5368 2010/05 英語 公開
Kashiwazaki G, Bando T, Shinohara K, Minoshima M, Kumamoto H, Nishijima S, Sugiyama H Kashiwazaki G, Bando T, Shinohara K, Minoshima M, Kumamoto H, Nishijima S, Sugiyama H G. Kashiwazaki; T. Bando; K.-i. Shinohara; M. Minoshima; H. Kumamoto; S. Nishijima; H. Sugiyama Alkylation of a human telomere sequence by heterotrimeric chlorambucil PI polyamide conjugates. Alkylation of a human telomere sequence by heterotrimeric chlorambucil PI polyamide conjugates. Alkylation of a human telomere sequence by heterotrimeric chlorambucil PI polyamide conjugates Bioorganic & medicinal chemistry, 18, 8, 2887-2893 Bioorganic & medicinal chemistry, 18, 8, 2887-2893 Bioorganic and Medicinal Chemistry, 18, 8, 2887-2893 2010/04 英語 公開
Sannohe Y, Sugiyama H Sannohe Y, Sugiyama H Y. Sannohe; H. Sugiyama Overview of formation of G-quadruplex structures. Overview of formation of G-quadruplex structures. Overview of formation of G-quadruplex structures Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 17, SUPPL. 40, Unit 17.2.1-17 Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.], Chapter 17, SUPPL. 40, Unit 17.2.1-17 Current Protocols in Nucleic Acid Chemistry, Chapter 17, SUPPL. 40, Unit 17.2.1-17 2010/03 英語 公開
Shinohara K, Sannohe Y, Kaieda S, Tanaka K, Osuga H, Tahara H, Xu Y, Kawase T, Bando T, Sugiyama H Shinohara K, Sannohe Y, Kaieda S, Tanaka K, Osuga H, Tahara H, Xu Y, Kawase T, Bando T, Sugiyama H K.-I. Shinohara; Y. Sannohe; S. Kaieda; K.-I. Tanaka; H. Osuga; H. Tahara; Y. Xu; T. Kawase; T. Bando; H. Sugiyama A chiral wedge molecule inhibits telomerase activity. A chiral wedge molecule inhibits telomerase activity. A chiral wedge molecule inhibits telomerase activity Journal of the American Chemical Society, 132, 11, 3778-3782 Journal of the American Chemical Society, 132, 11, 3778-3782 Journal of the American Chemical Society, 132, 11, 3778-3782 2010/03 英語 公開
Wang X, Nagase H, Watanabe T, Nobusue H, Suzuki T, Asami Y, Shinojima Y, Kawashima H, Takagi K, Mishra R, Igarashi J, Kimura M, Takayama T, Fukuda N, Sugiyama H Wang X, Nagase H, Watanabe T, Nobusue H, Suzuki T, Asami Y, Shinojima Y, Kawashima H, Takagi K, Mishra R, Igarashi J, Kimura M, Takayama T, Fukuda N, Sugiyama H X. Wang; H. Nagase; T. Watanabe; H. Nobusue; T. Suzuki; Y. Asami; Y. Shinojima; H. Kawashima; K. Takagi; R. Mishra; J. Igarashi; M. Kimura; T. Takayama; N. Fukuda; H. Sugiyama Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide. Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide. Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide Cancer science, 101, 3, 759-766 Cancer science, 101, 3, 759-766 Cancer Science, 101, 3, 759-766 2010/03 英語 公開
Shinohara K, Bando T, Sugiyama H Shinohara K, Bando T, Sugiyama H K.-I. Shinohara; T. Bando; H. Sugiyama Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition Anti-cancer drugs, 21, 3, 228-242 Anti-cancer drugs, 21, 3, 228-242 Anti-Cancer Drugs, 21, 3, 228-242 2010/03 英語 公開
Minoshima M, Bando T, Shinohara K, Kashiwazaki G, Nishijima S, Sugiyama H Minoshima M, Bando T, Shinohara K, Kashiwazaki G, Nishijima S, Sugiyama H M. Minoshima; T. Bando; K.-i. Shinohara; G. Kashiwazaki; S. Nishijima; H. Sugiyama Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI. Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI. Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI Bioorganic & medicinal chemistry, 18, 3, 1236-1243 Bioorganic & medicinal chemistry, 18, 3, 1236-1243 Bioorganic and Medicinal Chemistry, 18, 3, 1236-1243 2010/02/01 英語 公開
Endo M, Katsuda Y, Hidaka K, Sugiyama H Endo M, Katsuda Y, Hidaka K, Sugiyama H M. Endo; Y. Katsuda; K. Hidaka; H. Sugiyama Regulation of DNA methylation using different tensions of double strands constructed in a defined DNA nanostructure. Regulation of DNA methylation using different tensions of double strands constructed in a defined DNA nanostructure. Regulation of DNA methylation using different tensions of double strands constructed in a defined DNA nanostructure Journal of the American Chemical Society, 132, 5, 1592-1597 Journal of the American Chemical Society, 132, 5, 1592-1597 Journal of the American Chemical Society, 132, 5, 1592-1597 2010/02 英語 公開
Nishijima S, Shinohara K, Bando T, Minoshima M, Kashiwazaki G, Sugiyama H Nishijima S, Shinohara K, Bando T, Minoshima M, Kashiwazaki G, Sugiyama H S. Nishijima; K.-i. Shinohara; T. Bando; M. Minoshima; G. Kashiwazaki; H. Sugiyama Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content. Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content. Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content Bioorganic & medicinal chemistry, 18, 2, 978-983 Bioorganic & medicinal chemistry, 18, 2, 978-983 Bioorganic and Medicinal Chemistry, 18, 2, 978-983 2010/01 英語 公開
Minoshima M, Chou JC, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H Minoshima M, Chou JC, Lefebvre S, Bando T, Shinohara K, Gottesfeld JM, Sugiyama H M. Minoshima; J.C. Chou; S. Lefebvre; T. Bando; K.-i. Shinohara; J.M. Gottesfeld; H. Sugiyama Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes Bioorganic & medicinal chemistry, 18, 1, 168-174 Bioorganic & medicinal chemistry, 18, 1, 168-174 Bioorganic and Medicinal Chemistry, 18, 1, 168-174 2010/01 英語 公開
照島功祐,遠藤政幸,勝田陽介,日高久美,杉山弘 照島功祐,遠藤政幸,勝田陽介,日高久美,杉山弘 照島功祐,遠藤政幸,勝田陽介,日高久美,杉山弘 RNA ポリメラーゼのDNA ナノ構造上 での1分子観測 RNA ポリメラーゼのDNA ナノ構造上 での1分子観測 RNA ポリメラーゼのDNA ナノ構造上 での1分子観測 日本化学会第90 春季年会, 大阪,2010年3 月26 日-3 月 29 日 日本化学会第90 春季年会, 大阪,2010年3 月26 日-3 月 29 日 日本化学会第90 春季年会, 大阪,2010年3 月26 日-3 月 29 日 2010 日本語 公開
Endo M, Hidaka K, Kato T, Namba K, Sugiyama H Endo M, Hidaka K, Kato T, Namba K, Sugiyama H M. Endo; K. Hidaka; T. Kato; K. Namba; H. Sugiyama DNA prism structures constructed by folding of multiple rectangular arms. DNA prism structures constructed by folding of multiple rectangular arms. DNA prism structures constructed by folding of multiple rectangular arms Journal of the American Chemical Society, 131, 43, 15570-15571 Journal of the American Chemical Society, 131, 43, 15570-15571 Journal of the American Chemical Society, 131, 43, 15570-15571 2009/11 英語 公開
Kino K, Sugasawa K, Mizuno T, Bando T, Sugiyama H, Akita M, Miyazawa H, Hanaoka F Kino K, Sugasawa K, Mizuno T, Bando T, Sugiyama H, Akita M, Miyazawa H, Hanaoka F K. Kino; K. Sugasawa; T. Mizuno; T. Bando; H. Sugiyama; M. Akita; H. Miyazawa; F. Hanaoka Eukaryotic DNA polymerases alpha, beta and epsilon incorporate guanine opposite 2,2,4-triamino-5(2H)-oxazolone. Eukaryotic DNA polymerases alpha, beta and epsilon incorporate guanine opposite 2,2,4-triamino-5(2H)-oxazolone. Eukaryotic DNA polymerases α, β and ε incorporate guanine opposite 2,2,4-triamino-5(2H)-oxazolone Chembiochem : a European journal of chemical biology, 10, 16, 2613-2616 Chembiochem : a European journal of chemical biology, 10, 16, 2613-2616 ChemBioChem, 10, 16, 2613-2616 2009/11 英語 公開
Endo M, Sugiyama H Endo M, Sugiyama H M. Endo; H. Sugiyama Chemical approaches to DNA nanotechnology. Chemical approaches to DNA nanotechnology. Chemical approaches to DNA nanotechnology Chembiochem : a European journal of chemical biology, 10, 15, 2420-2443 Chembiochem : a European journal of chemical biology, 10, 15, 2420-2443 ChemBioChem, 10, 15, 2420-2443 2009/10 英語 公開
Webba da Silva M, Trajkovski M, Sannohe Y, Ma'ani Hessari N, Sugiyama H, Plavec J Webba da Silva M, Trajkovski M, Sannohe Y, Ma'ani Hessari N, Sugiyama H, Plavec J M. Webba da Silva; M. Trajkovski; Y. Sannohe; N.M. Hessari; H. Sugiyama; J. Plavec Design of a G-quadruplex topology through glycosidic bond angles. Design of a G-quadruplex topology through glycosidic bond angles. Design of a G-quadruplex topology through glycosidic bond angles Angewandte Chemie (International ed. in English), 48, 48, 9167-9170 Angewandte Chemie (International ed. in English), 48, 48, 9167-9170 Angewandte Chemie - International Edition, 48, 48, 9167-9170 2009 英語 公開
E.-H. Yao; N. Fukuda; T. Ueno; H. Matsuda; H. Nagase; Y. Matsumoto; H. Sugiyama; K. Matsumoto E.-H. Yao; N. Fukuda; T. Ueno; H. Matsuda; H. Nagase; Y. Matsumoto; H. Sugiyama; K. Matsumoto E.-H. Yao; N. Fukuda; T. Ueno; H. Matsuda; H. Nagase; Y. Matsumoto; H. Sugiyama; K. Matsumoto A pyrrole-imidazole polyamide targeting transforming growth factor-β1 inhibits restenosis and preserves endothelialization in the injured artery A pyrrole-imidazole polyamide targeting transforming growth factor-β1 inhibits restenosis and preserves endothelialization in the injured artery A pyrrole-imidazole polyamide targeting transforming growth factor-β1 inhibits restenosis and preserves endothelialization in the injured artery Cardiovascular Research, 81, 4, 797-804 Cardiovascular Research, 81, 4, 797-804 Cardiovascular Research, 81, 4, 797-804 2009 日本語 公開
R. Tashiro; H. Sugiyama R. Tashiro; H. Sugiyama R. Tashiro; H. Sugiyama Photochemistry of 5-Bromouracil- Or 5-Iodouracil-containing DNA: Probe for DNA structure and charge transfer along DNA Photochemistry of 5-Bromouracil- Or 5-Iodouracil-containing DNA: Probe for DNA structure and charge transfer along DNA Photochemistry of 5-Bromouracil- Or 5-Iodouracil-containing DNA: Probe for DNA structure and charge transfer along DNA Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 67, 12, 1261-1273 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 67, 12, 1261-1273 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 67, 12, 1261-1273 2009 日本語 公開
Xu Y, Sato H, Sannohe Y, Shinohara K, Sugiyama H Xu Y, Sato H, Sannohe Y, Shinohara K, Sugiyama H Y. Xu; H. Sato; Y. Sannohe; K.-I. Shinohara; H. Sugiyama Stable lariat formation based on a G-quadruplex scaffold. Stable lariat formation based on a G-quadruplex scaffold. Stable lariat formation based on a G-quadruplex scaffold Journal of the American Chemical Society, 130, 49, 16470-16471 Journal of the American Chemical Society, 130, 49, 16470-16471 Journal of the American Chemical Society, 130, 49, 16470-16471 2008/12 英語 公開
T. Bando; H. Sugiyama T. Bando; H. Sugiyama T. Bando; H. Sugiyama The chemical biology that controls DNA function and structure The chemical biology that controls DNA function and structure The chemical biology that controls DNA function and structure Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 63, 10, 1016-1027 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 63, 10, 1016-1027 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 63, 10, 1016-1027 2005 日本語 公開
H. Iida; H. Sugiyama H. Iida; H. Sugiyama H. Iida; H. Sugiyama Recognition of DNA sequences by pyrrole-imidazole polyamide: Rational drug design in the post-genome era Recognition of DNA sequences by pyrrole-imidazole polyamide: Rational drug design in the post-genome era Recognition of DNA sequences by pyrrole-imidazole polyamide: Rational drug design in the post-genome era Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 58, 10, 975-987 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 58, 10, 975-987 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 58, 10, 975-987 2000 日本語 公開
H. Sugiyama H. Sugiyama H. Sugiyama Mechanism of oxidative DNA strand scission Mechanism of oxidative DNA strand scission Mechanism of oxidative DNA strand scission Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 40, 10, 1444-1456 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 40, 10, 1444-1456 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 40, 10, 1444-1456 1995 日本語 公開

  • <<
  • >>
  • 表示
タイトル言語:
Misc
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
中田栄司,上床知佐奈,劉芳芳,清中茂樹,森泰生,勝田陽介,遠藤政幸,杉山弘,森井孝 中田栄司,上床知佐奈,劉芳芳,清中茂樹,森泰生,勝田陽介,遠藤政幸,杉山弘,森井孝 中田栄司,上床知佐奈,劉芳芳,清中茂樹,森泰生,勝田陽介,遠藤政幸,杉山弘,森井孝 DNA origami上への機能性タンパク質固定化技術の開発 DNA origami上への機能性タンパク質固定化技術の開発 DNA origami上への機能性タンパク質固定化技術の開発 第5回バイオ関連化学シンポジウム,つくば国際会議場「エポカルつくば」,2011.9.12-14 第5回バイオ関連化学シンポジウム,つくば国際会議場「エポカルつくば」,2011.9.12-14 第5回バイオ関連化学シンポジウム,つくば国際会議場「エポカルつくば」,2011.9.12-14 2011 日本語 公開
タイトル言語:
外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
特定領域研究 DNA配列に基づくテーラーメード抗癌剤 2005〜2009
基盤研究(A) DNAの構造と反応性に関するケミカルバイオロジー研究 2007〜2010
特別研究員奨励費 代表 DNAオリガミを用いた生体分子ナノシステムの構築 2011〜2013
基盤研究(S) 代表 分子科学的アプローチによる遺伝子発現の制御と機構の解明 2012〜2016
基盤研究(S) 代表 分子科学的アプローチによる遺伝子発現の制御と機構の解明 2012/04/01〜2017/03/31
基盤研究(S) 代表 分子科学的アプローチによる遺伝子発現の制御と機構の解明 (平成26年度分) 2014/04/01〜2015/03/31
基盤研究(S) 代表 分子科学的アプローチによる遺伝子発現の制御と機構の解明 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(S) 代表 分子科学的アプローチによる遺伝子発現の制御と機構の解明 (平成27年度分) 2015/04/01〜2016/03/31
外部資金:競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
国際共同研究事業国際化学研究協力事業 杉山 弘 完全長ヒトテロメア突出末端の構造のダイナミクスとサブドメインの安定性 (平成26年度分) 2014/04/01〜2015/03/31
国際共同研究事業国際化学研究協力事業 杉山 弘 完全長ヒトテロメア突出末端の構造のダイナミクスとサブドメインの安定性 (平成27年度分) 2015/04/01〜2016/03/31
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
生物化学ゼミナールⅠA 前期 理学研究科 2011/04〜2012/03
生物化学ゼミナールⅠB 後期 理学研究科 2011/04〜2012/03
生物化学ゼミナールⅠC 前期 理学研究科 2011/04〜2012/03
生物化学ゼミナールⅠD 後期 理学研究科 2011/04〜2012/03
ケミカルバイオロジー概論 前期 理学研究科 2011/04〜2012/03
生物化学演習ⅠA 前期 理学研究科 2011/04〜2012/03
生物化学演習ⅠB 後期 理学研究科 2011/04〜2012/03
生物化学演習ⅠC 前期 理学研究科 2011/04〜2012/03
生物化学演習ⅠD 後期 理学研究科 2011/04〜2012/03
ケミカル・バイオロジー 前期 理学部 2011/04〜2012/03
現代化学入門A Introduction to Modern Chemistry 前期 全学共通科目 2011/04〜2012/03
化学課題研究16 通年 理学部 2011/04〜2012/03
ケミカル・バイオロジー Chemical Biology 前期 理学部 2012/04〜2013/03
化学課題研究16 Special study course II (Chemistry) 16 通年 理学部 2012/04〜2013/03
生物化学演習 Exercises in Biochemistry 後期 理学部 2012/04〜2013/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2012/04〜2013/03
ケミカル・バイオロジー Chemical Biology 前期 理学部 2013/04〜2014/03
生物化学演習 Exercises in Biochemistry 後期 理学部 2013/04〜2014/03
化学課題研究16 Special study course II (Chemistry) 16 通年 理学部 2013/04〜2014/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2013/04〜2014/03
ケミカル・バイオロジー Chemical Biology 前期 理学部 2014/04〜2015/03
生物化学演習 Exercises in Biochemistry 後期 理学部 2014/04〜2015/03
化学課題研究16 Special study course II (Chemistry) 16 通年 理学部 2014/04〜2015/03
ケミカルバイオロジー概論 Principles of Chemical Biology 前期 理学研究科 2014/04〜2015/03
生体分子機能論 Advanced Course in Molecular Biology and Biochemistry 後期 理学研究科 2014/04〜2015/03
生物化学ゼミナールIA Seminar on Biochemistry IA 前期 理学研究科 2014/04〜2015/03
生物化学ゼミナールIB Seminar on Biochemistry IB 後期 理学研究科 2014/04〜2015/03
生物化学ゼミナールIC Seminar on Biochemistry IC 前期 理学研究科 2014/04〜2015/03
生物化学ゼミナールID Seminar on Biochemistry ID 後期 理学研究科 2014/04〜2015/03
生物化学演習IA Advanced Biochemistry IA 前期 理学研究科 2014/04〜2015/03
生物化学演習IB Advanced Biochemistry IB 後期 理学研究科 2014/04〜2015/03
生物化学演習IC Advanced Biochemistry IC 前期 理学研究科 2014/04〜2015/03
生物化学演習ID Advanced Biochemistry ID 後期 理学研究科 2014/04〜2015/03
化学課題研究16 Special study course II (Chemistry) 16 通年 理学部 2015/04〜2016/03
ケミカルバイオロジー概論 Principles of Chemical Biology 前期 理学研究科 2015/04〜2016/03
生物化学II Biochemistry II 前期 理学部 2015/04〜2016/03
生物化学IV Biochemistry IV 前期 理学部 2015/04〜2016/03
生物化学ゼミナールIA Seminar on Biochemistry IA 前期 理学研究科 2015/04〜2016/03
生物化学ゼミナールIB Seminar on Biochemistry IB 後期 理学研究科 2015/04〜2016/03
生物化学ゼミナールIC Seminar on Biochemistry IC 前期 理学研究科 2015/04〜2016/03
生物化学ゼミナールID Seminar on Biochemistry ID 後期 理学研究科 2015/04〜2016/03
生物化学演習IA Advanced Biochemistry IA 前期 理学研究科 2015/04〜2016/03
生物化学演習IB Advanced Biochemistry IB 後期 理学研究科 2015/04〜2016/03
生物化学演習IC Advanced Biochemistry IC 前期 理学研究科 2015/04〜2016/03
生物化学演習ID Advanced Biochemistry ID 後期 理学研究科 2015/04〜2016/03
生物化学演習 Exercises in Biochemistry 後期 理学部 2015/04〜2016/03
化学課題研究16 Special study course II (Chemistry) 16 通年 理学部 2016/04〜2017/03
ケミカルバイオロジー概論 Principles of Chemical Biology 前期 理学研究科 2016/04〜2017/03
生体分子機能論 Advanced Course in Molecular Biology and Biochemistry 後期 理学研究科 2016/04〜2017/03
生物化学II Biochemistry II 前期 理学部 2016/04〜2017/03
生物化学IV Biochemistry IV 前期 理学部 2016/04〜2017/03
生物化学ゼミナールIA Seminar on Biochemistry IA 前期 理学研究科 2016/04〜2017/03
生物化学ゼミナールIB Seminar on Biochemistry IB 後期 理学研究科 2016/04〜2017/03
生物化学ゼミナールIC Seminar on Biochemistry IC 前期 理学研究科 2016/04〜2017/03
生物化学ゼミナールID Seminar on Biochemistry ID 後期 理学研究科 2016/04〜2017/03
生物化学演習IA Advanced Biochemistry IA 前期 理学研究科 2016/04〜2017/03
生物化学演習IB Advanced Biochemistry IB 後期 理学研究科 2016/04〜2017/03
生物化学演習IC Advanced Biochemistry IC 前期 理学研究科 2016/04〜2017/03
生物化学演習ID Advanced Biochemistry ID 後期 理学研究科 2016/04〜2017/03
生物化学演習 Exercises in Biochemistry 後期 理学部 2016/04〜2017/03

  • <<
  • >>
  • 表示
部局運営(役職等)
役職名 期間
理学部・教育委員会委員 2016/04/01〜2017/03/31
理学部・教育委員会 少人数担任委員会委員 2016/04/01〜2017/03/31