中川 靖章

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氏名(漢字／フリガナ／アルファベット表記)
中川 靖章／ナカガワ ヤスアキ／Nakagawa, Yasuaki
所属部署・職名(部局／所属／講座等／職名)
医学部附属病院／内科（循環器内科）／助教
学内兼務
部局 所属 講座等 職名
医学研究科 医学研究科 医学専攻
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士（医学） 京都大学
researchmap URL
https://researchmap.jp/read0201551
研究テーマ
(日本語)
心肥大・心不全の発症・進展におけるメカニズムの解明、及びそれに基づく、新たな診断法・治療法の開発
研究概要
(日本語)
心肥大・心不全時に遺伝子発現が亢進するナトリウム利尿ペプチドの遺伝子発現調節メカニズムの解明に基づき、心肥大・心不全の発症・進展に関わる種々の分子について、ミトコンドリア機能や細胞内環境との関連に着目しながら研究をすすめている。また、BNPのプロセシングにおける糖鎖修飾に関連した分子メカニズムを明らかとするとともに、その病態生理学的意義の解明について研究を進めている。
研究分野（キーワード）
キーワード(日本語) キーワード(英語)
ナトリウム利尿ペプチド Natriuretic Peptide
心不全 Heart failure
心肥大 Cardiac hypertrophy
糖鎖 glycosylation
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Nakagawa Y, Nishikimi T, Kuwahara K Nakagawa Y, Nishikimi T, Kuwahara K Nakagawa Y, Nishikimi T, Kuwahara K Atrial and brain natriuretic peptides: Hormones secreted from the heart. Atrial and brain natriuretic peptides: Hormones secreted from the heart. Atrial and brain natriuretic peptides: Hormones secreted from the heart. Peptides Peptides Peptides 2018/05 有 公開
Takahama H, Takashio S, Nishikimi T, Hayashi T, Nagai-Okatani C, Nakagawa Y, Amaki M, Ohara T, Hasegawa T, Sugano Y, Kanzaki H, Yasuda S, Kangawa K, Minamino N, Anzai T Takahama H, Takashio S, Nishikimi T, Hayashi T, Nagai-Okatani C, Nakagawa Y, Amaki M, Ohara T, Hasegawa T, Sugano Y, Kanzaki H, Yasuda S, Kangawa K, Minamino N, Anzai T Takahama H, Takashio S, Nishikimi T, Hayashi T, Nagai-Okatani C, Nakagawa Y, Amaki M, Ohara T, Hasegawa T, Sugano Y, Kanzaki H, Yasuda S, Kangawa K, Minamino N, Anzai T Ratio of pro-B-type natriuretic peptide (BNP) to total BNP is decreased in mild, but not severe, acute decompensated heart failure patients: A novel compensatory mechanism for acute heart failure. Ratio of pro-B-type natriuretic peptide (BNP) to total BNP is decreased in mild, but not severe, acute decompensated heart failure patients: A novel compensatory mechanism for acute heart failure. Ratio of pro-B-type natriuretic peptide (BNP) to total BNP is decreased in mild, but not severe, acute decompensated heart failure patients: A novel compensatory mechanism for acute heart failure. International journal of cardiology, 258, 165-171 International journal of cardiology, 258, 165-171 International journal of cardiology, 258, 165-171 2018/05 有 公開
Nakagawa Y, Nishikimi T, Sakai H, Ohno S, Kinoshita H, Inazumi H, Moriuchi K, Kuwahara K, Horie M, Kimura T Nakagawa Y, Nishikimi T, Sakai H, Ohno S, Kinoshita H, Inazumi H, Moriuchi K, Kuwahara K, Horie M, Kimura T Nakagawa Y, Nishikimi T, Sakai H, Ohno S, Kinoshita H, Inazumi H, Moriuchi K, Kuwahara K, Horie M, Kimura T Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report. Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report. Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report. Clinical biochemistry, 52, 148-152 Clinical biochemistry, 52, 148-152 Clinical biochemistry, 52, 148-152 2018/02 有 公開
Nishikimi T, Nakagawa Y Nishikimi T, Nakagawa Y Nishikimi T, Nakagawa Y Adrenomedullin as a Biomarker of Heart Failure. Adrenomedullin as a Biomarker of Heart Failure. Adrenomedullin as a Biomarker of Heart Failure. Heart failure clinics, 14, 1, 49-55 Heart failure clinics, 14, 1, 49-55 Heart failure clinics, 14, 1, 49-55 2018/01 有 公開
Nakagawa Y, Nishikimi T, Kuwahara K, Fujishima A, Oka S, Tsutamoto T, Kinoshita H, Nakao K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T, Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE, Kangawa K, Minamino N, Nakao K, Kimura T Nakagawa Y, Nishikimi T, Kuwahara K, Fujishima A, Oka S, Tsutamoto T, Kinoshita H, Nakao K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T, Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE, Kangawa K, Minamino N, Nakao K, Kimura T Nakagawa Y, Nishikimi T, Kuwahara K, Fujishima A, Oka S, Tsutamoto T, Kinoshita H, Nakao K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T, Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE, Kangawa K, Minamino N, Nakao K, Kimura T MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts. MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts. MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts. Journal of the American Heart Association, 6, 2 Journal of the American Heart Association, 6, 2 Journal of the American Heart Association, 6, 2 2017/02 有 公開
Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy. The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy. The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy. Cardiovascular research, 109, 1, 162-173 Cardiovascular research, 109, 1, 162-173 Cardiovascular research, 109, 1, 162-173 2016/01 有 公開
Nishikimi T, Nakagawa Y, Minamino N, Ikeda M, Tabei K, Fujishima A, Takayama K, Akimoto K, Yamada C, Nakao K, Minami T, Kuwabara Y, Kinoshita H, Tsutamoto T, Ishimitsu T, Kangawa K, Kuwahara K, Nakao K Nishikimi T, Nakagawa Y, Minamino N, Ikeda M, Tabei K, Fujishima A, Takayama K, Akimoto K, Yamada C, Nakao K, Minami T, Kuwabara Y, Kinoshita H, Tsutamoto T, Ishimitsu T, Kangawa K, Kuwahara K, Nakao K Nishikimi T, Nakagawa Y, Minamino N, Ikeda M, Tabei K, Fujishima A, Takayama K, Akimoto K, Yamada C, Nakao K, Minami T, Kuwabara Y, Kinoshita H, Tsutamoto T, Ishimitsu T, Kangawa K, Kuwahara K, Nakao K Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites. Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites. Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites. American journal of physiology. Regulatory, integrative and comparative physiology, 309, 6, R639-49 American journal of physiology. Regulatory, integrative and comparative physiology, 309, 6, R639-49 American journal of physiology. Regulatory, integrative and comparative physiology, 309, 6, R639-49 2015/09 有 公開
Nakagawa Y, Yasuno S, Kuwahara K Nakagawa Y, Yasuno S, Kuwahara K Nakagawa Y, Yasuno S, Kuwahara K Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure. Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure. Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure. Circulation journal : official journal of the Japanese Circulation Society, 79, 9, 1893-1894 Circulation journal : official journal of the Japanese Circulation Society, 79, 9, 1893-1894 Circulation journal : official journal of the Japanese Circulation Society, 79, 9, 1893-1894 2015 有 公開
Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami T, Yamada C, Shibata J, Nakao K, Cho K, Arai Y, Yasuno S, Nishikimi T, Ueshima K, Kamakura S, Nishida M, Kiyonaka S, Mori Y, Kimura T, Kangawa K, Nakao K Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami T, Yamada C, Shibata J, Nakao K, Cho K, Arai Y, Yasuno S, Nishikimi T, Ueshima K, Kamakura S, Nishida M, Kiyonaka S, Mori Y, Kimura T, Kangawa K, Nakao K Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami T, Yamada C, Shibata J, Nakao K, Cho K, Arai Y, Yasuno S, Nishikimi T, Ueshima K, Kamakura S, Nishida M, Kiyonaka S, Mori Y, Kimura T, Kangawa K, Nakao K Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure. Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure. Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure. Cardiovascular research, 104, 1, 183-193 Cardiovascular research, 104, 1, 183-193 Cardiovascular research, 104, 1, 183-193 2014/10 有 公開
Nakagawa Y, Nishikimi T, Kuwahara K, Yasuno S, Kinoshita H, Kuwabara Y, Nakao K, Minami T, Yamada C, Ueshima K, Ikeda Y, Okamoto H, Horii K, Nagata K, Kangawa K, Minamino N, Nakao K Nakagawa Y, Nishikimi T, Kuwahara K, Yasuno S, Kinoshita H, Kuwabara Y, Nakao K, Minami T, Yamada C, Ueshima K, Ikeda Y, Okamoto H, Horii K, Nagata K, Kangawa K, Minamino N, Nakao K Nakagawa Y, Nishikimi T, Kuwahara K, Yasuno S, Kinoshita H, Kuwabara Y, Nakao K, Minami T, Yamada C, Ueshima K, Ikeda Y, Okamoto H, Horii K, Nagata K, Kangawa K, Minamino N, Nakao K The effects of super-flux (high performance) dialyzer on plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-Terminal proBNP in end-stage renal disease patients on dialysis. The effects of super-flux (high performance) dialyzer on plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-Terminal proBNP in end-stage renal disease patients on dialysis. The effects of super-flux (high performance) dialyzer on plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-Terminal proBNP in end-stage renal disease patients on dialysis. PloS one, 9, 3, e92314 PloS one, 9, 3, e92314 PloS one, 9, 3, e92314 2014 有 公開
Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK Uosaki H, Magadum A, Seo K, Fukushima H, Takeuchi A, Nakagawa Y, Moyes KW, Narazaki G, Kuwahara K, Laflamme M, Matsuoka S, Nakatsuji N, Nakao K, Kwon C, Kass DA, Engel FB, Yamashita JK Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells. Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells. Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells. Circulation. Cardiovascular genetics, 6, 6, 624-633 Circulation. Cardiovascular genetics, 6, 6, 624-633 Circulation. Cardiovascular genetics, 6, 6, 624-633 2013/12 有 公開
Yasuno S, Kuwahara K, Kinoshita H, Yamada C, Nakagawa Y, Usami S, Kuwabara Y, Ueshima K, Harada M, Nishikimi T, Nakao K Yasuno S, Kuwahara K, Kinoshita H, Yamada C, Nakagawa Y, Usami S, Kuwabara Y, Ueshima K, Harada M, Nishikimi T, Nakao K Yasuno S, Kuwahara K, Kinoshita H, Yamada C, Nakagawa Y, Usami S, Kuwabara Y, Ueshima K, Harada M, Nishikimi T, Nakao K Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy. Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy. Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy. British journal of pharmacology, 170, 7, 1384-1395 British journal of pharmacology, 170, 7, 1384-1395 British journal of pharmacology, 170, 7, 1384-1395 2013/12 有 公開
Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Nakao K Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Nakao K Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Nakao K Adrenomedullin in cardiovascular disease: a useful biomarker, its pathological roles and therapeutic application. Adrenomedullin in cardiovascular disease: a useful biomarker, its pathological roles and therapeutic application. Adrenomedullin in cardiovascular disease: a useful biomarker, its pathological roles and therapeutic application. Current protein & peptide science, 14, 4, 256-267 Current protein & peptide science, 14, 4, 256-267 Current protein & peptide science, 14, 4, 256-267 2013/06 有 公開
Kuwabara Y, Kuwahara K, Takano M, Kinoshita H, Arai Y, Yasuno S, Nakagawa Y, Igata S, Usami S, Minami T, Yamada Y, Nakao K, Yamada C, Shibata J, Nishikimi T, Ueshima K, Nakao K Kuwabara Y, Kuwahara K, Takano M, Kinoshita H, Arai Y, Yasuno S, Nakagawa Y, Igata S, Usami S, Minami T, Yamada Y, Nakao K, Yamada C, Shibata J, Nishikimi T, Ueshima K, Nakao K Kuwabara Y, Kuwahara K, Takano M, Kinoshita H, Arai Y, Yasuno S, Nakagawa Y, Igata S, Usami S, Minami T, Yamada Y, Nakao K, Yamada C, Shibata J, Nishikimi T, Ueshima K, Nakao K Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts. Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts. Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts. Journal of the American Heart Association, 2, 3, e000150 Journal of the American Heart Association, 2, 3, e000150 Journal of the American Heart Association, 2, 3, e000150 2013/05 有 公開
Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Minamino N, Nakao K Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Minamino N, Nakao K Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Minamino N, Nakao K Complexity of molecular forms of B-type natriuretic peptide in heart failure. Complexity of molecular forms of B-type natriuretic peptide in heart failure. Complexity of molecular forms of B-type natriuretic peptide in heart failure. Heart (British Cardiac Society), 99, 10, 677-679 Heart (British Cardiac Society), 99, 10, 677-679 Heart (British Cardiac Society), 99, 10, 677-679 2013/05 有 公開
Nishikimi T, Okamoto H, Nakamura M, Ogawa N, Horii K, Nagata K, Nakagawa Y, Kinoshita H, Yamada C, Nakao K, Minami T, Kuwabara Y, Kuwahara K, Masuda I, Kangawa K, Minamino N, Nakao K Nishikimi T, Okamoto H, Nakamura M, Ogawa N, Horii K, Nagata K, Nakagawa Y, Kinoshita H, Yamada C, Nakao K, Minami T, Kuwabara Y, Kuwahara K, Masuda I, Kangawa K, Minamino N, Nakao K Nishikimi T, Okamoto H, Nakamura M, Ogawa N, Horii K, Nagata K, Nakagawa Y, Kinoshita H, Yamada C, Nakao K, Minami T, Kuwabara Y, Kuwahara K, Masuda I, Kangawa K, Minamino N, Nakao K Direct immunochemiluminescent assay for proBNP and total BNP in human plasma proBNP and total BNP levels in normal and heart failure. Direct immunochemiluminescent assay for proBNP and total BNP in human plasma proBNP and total BNP levels in normal and heart failure. Direct immunochemiluminescent assay for proBNP and total BNP in human plasma proBNP and total BNP levels in normal and heart failure. PloS one, 8, 1, e53233 PloS one, 8, 1, e53233 PloS one, 8, 1, e53233 2013 有 公開
Minami T, Kuwahara K, Nakagawa Y, Takaoka M, Kinoshita H, Nakao K, Kuwabara Y, Yamada Y, Yamada C, Shibata J, Usami S, Yasuno S, Nishikimi T, Ueshima K, Sata M, Nakano H, Seno T, Kawahito Y, Sobue K, Kimura A, Nagai R, Nakao K Minami T, Kuwahara K, Nakagawa Y, Takaoka M, Kinoshita H, Nakao K, Kuwabara Y, Yamada Y, Yamada C, Shibata J, Usami S, Yasuno S, Nishikimi T, Ueshima K, Sata M, Nakano H, Seno T, Kawahito Y, Sobue K, Kimura A, Nagai R, Nakao K Minami T, Kuwahara K, Nakagawa Y, Takaoka M, Kinoshita H, Nakao K, Kuwabara Y, Yamada Y, Yamada C, Shibata J, Usami S, Yasuno S, Nishikimi T, Ueshima K, Sata M, Nakano H, Seno T, Kawahito Y, Sobue K, Kimura A, Nagai R, Nakao K Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice. Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice. Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice. The EMBO journal, 31, 23, 4428-4440 The EMBO journal, 31, 23, 4428-4440 The EMBO journal, 31, 23, 4428-4440 2012/11 有 公開
Yasuno S, Fujimoto A, Nakagawa Y, Kuwahara K, Ueshima K Yasuno S, Fujimoto A, Nakagawa Y, Kuwahara K, Ueshima K Yasuno S, Fujimoto A, Nakagawa Y, Kuwahara K, Ueshima K Fixed-dose combination therapy of candesartan cilexetil and amlodipine besilate for the treatment of hypertension in Japan. Fixed-dose combination therapy of candesartan cilexetil and amlodipine besilate for the treatment of hypertension in Japan. Fixed-dose combination therapy of candesartan cilexetil and amlodipine besilate for the treatment of hypertension in Japan. Expert review of cardiovascular therapy, 10, 5, 577-583 Expert review of cardiovascular therapy, 10, 5, 577-583 Expert review of cardiovascular therapy, 10, 5, 577-583 2012/05 有 公開
Nishikimi T, Ikeda M, Takeda Y, Ishimitsu T, Shibasaki I, Fukuda H, Kinoshita H, Nakagawa Y, Kuwahara K, Nakao K Nishikimi T, Ikeda M, Takeda Y, Ishimitsu T, Shibasaki I, Fukuda H, Kinoshita H, Nakagawa Y, Kuwahara K, Nakao K Nishikimi T, Ikeda M, Takeda Y, Ishimitsu T, Shibasaki I, Fukuda H, Kinoshita H, Nakagawa Y, Kuwahara K, Nakao K The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure. The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure. The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure. Heart (British Cardiac Society), 98, 2, 152-161 Heart (British Cardiac Society), 98, 2, 152-161 Heart (British Cardiac Society), 98, 2, 152-161 2012/01 有 公開
Hata L, Murakami M, Kuwahara K, Nakagawa Y, Kinoshita H, Usami S, Yasuno S, Fujiwara M, Kuwabara Y, Minami T, Yamada Y, Yamada C, Nakao K, Ueshima K, Nishikimi T, Nakao K Hata L, Murakami M, Kuwahara K, Nakagawa Y, Kinoshita H, Usami S, Yasuno S, Fujiwara M, Kuwabara Y, Minami T, Yamada Y, Yamada C, Nakao K, Ueshima K, Nishikimi T, Nakao K Hata L, Murakami M, Kuwahara K, Nakagawa Y, Kinoshita H, Usami S, Yasuno S, Fujiwara M, Kuwabara Y, Minami T, Yamada Y, Yamada C, Nakao K, Ueshima K, Nishikimi T, Nakao K Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes. Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes. Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes. Journal of molecular and cellular cardiology, 50, 6, 972-981 Journal of molecular and cellular cardiology, 50, 6, 972-981 Journal of molecular and cellular cardiology, 50, 6, 972-981 2011/06 有 公開
Kuwahara K, Kinoshita H, Kuwabara Y, Nakagawa Y, Usami S, Minami T, Yamada Y, Fujiwara M, Nakao K Kuwahara K, Kinoshita H, Kuwabara Y, Nakagawa Y, Usami S, Minami T, Yamada Y, Fujiwara M, Nakao K Kuwahara K, Kinoshita H, Kuwabara Y, Nakagawa Y, Usami S, Minami T, Yamada Y, Fujiwara M, Nakao K Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression. Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression. Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression. Molecular and cellular biology, 30, 17, 4134-4148 Molecular and cellular biology, 30, 17, 4134-4148 Molecular and cellular biology, 30, 17, 4134-4148 2010/09 有 公開
Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K Kinoshita H, Kuwahara K, Nishida M, Jian Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Li Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circulation research, 106, 12, 1849-1860 Circulation research, 106, 12, 1849-1860 Circulation research, 106, 12, 1849-1860 2010/06 有 公開
Nakagawa Y, Kuwahara K, Takemura G, Akao M, Kato M, Arai Y, Takano M, Harada M, Murakami M, Nakanishi M, Usami S, Yasuno S, Kinoshita H, Fujiwara M, Ueshima K, Nakao K Nakagawa Y, Kuwahara K, Takemura G, Akao M, Kato M, Arai Y, Takano M, Harada M, Murakami M, Nakanishi M, Usami S, Yasuno S, Kinoshita H, Fujiwara M, Ueshima K, Nakao K Nakagawa Y, Kuwahara K, Takemura G, Akao M, Kato M, Arai Y, Takano M, Harada M, Murakami M, Nakanishi M, Usami S, Yasuno S, Kinoshita H, Fujiwara M, Ueshima K, Nakao K p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. Circulation research, 105, 8, 746-754 Circulation research, 105, 8, 746-754 Circulation research, 105, 8, 746-754 2009/10 有 公開
Kinoshita H, Kuwahara K, Takano M, Arai Y, Kuwabara Y, Yasuno S, Nakagawa Y, Nakanishi M, Harada M, Fujiwara M, Murakami M, Ueshima K, Nakao K Kinoshita H, Kuwahara K, Takano M, Arai Y, Kuwabara Y, Yasuno S, Nakagawa Y, Nakanishi M, Harada M, Fujiwara M, Murakami M, Ueshima K, Nakao K Kinoshita H, Kuwahara K, Takano M, Arai Y, Kuwabara Y, Yasuno S, Nakagawa Y, Nakanishi M, Harada M, Fujiwara M, Murakami M, Ueshima K, Nakao K T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. T-type Ca2+ channel blockade prevents sudden death in mice with heart failure. Circulation, 120, 9, 743-752 Circulation, 120, 9, 743-752 Circulation, 120, 9, 743-752 2009/09 有 公開
Yasuno S, Usami S, Kuwahara K, Nakanishi M, Arai Y, Kinoshita H, Nakagawa Y, Fujiwara M, Murakami M, Ueshima K, Harada M, Nakao K Yasuno S, Usami S, Kuwahara K, Nakanishi M, Arai Y, Kinoshita H, Nakagawa Y, Fujiwara M, Murakami M, Ueshima K, Harada M, Nakao K Yasuno S, Usami S, Kuwahara K, Nakanishi M, Arai Y, Kinoshita H, Nakagawa Y, Fujiwara M, Murakami M, Ueshima K, Harada M, Nakao K Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death. Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death. Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death. American journal of physiology. Heart and circulatory physiology, 296, 6, H1804-10 American journal of physiology. Heart and circulatory physiology, 296, 6, H1804-10 American journal of physiology. Heart and circulatory physiology, 296, 6, H1804-10 2009/06 有 公開
Usami S, Kishimoto I, Saito Y, Harada M, Kuwahara K, Nakagawa Y, Nakanishi M, Yasuno S, Kangawa K, Nakao K Usami S, Kishimoto I, Saito Y, Harada M, Kuwahara K, Nakagawa Y, Nakanishi M, Yasuno S, Kangawa K, Nakao K Usami S, Kishimoto I, Saito Y, Harada M, Kuwahara K, Nakagawa Y, Nakanishi M, Yasuno S, Kangawa K, Nakao K Association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese. Association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese. Association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese. Hypertension research : official journal of the Japanese Society of Hypertension, 31, 1, 89-96 Hypertension research : official journal of the Japanese Society of Hypertension, 31, 1, 89-96 Hypertension research : official journal of the Japanese Society of Hypertension, 31, 1, 89-96 2008/01 有 公開
M. Nakanishi; M. Harada; K. Kuwahara; Y. Nakagawa; S. Usami; H. Kinoshita; M. Fujiwara; K. Nakao; N. Marui; K. Tambara; K. Nishina; M. Komeda; K. Ueshima M. Nakanishi; M. Harada; K. Kuwahara; Y. Nakagawa; S. Usami; H. Kinoshita; M. Fujiwara; K. Nakao; N. Marui; K. Tambara; K. Nishina; M. Komeda; K. Ueshima A case report of right ventricular perforation 6 months after permanent pacemaker implantation A case report of right ventricular perforation 6 months after permanent pacemaker implantation Respiration and Circulation, 56, 8, 861-865 Respiration and Circulation, 56, 8, 861-865 , 56, 8, 861-865 2008 有 日本語 公開
Nakanishi M, Harada M, Kishimoto I, Kuwahara K, Kawakami R, Nakagawa Y, Yasuno S, Usami S, Kinoshita H, Adachi Y, Fukamizu A, Saito Y, Nakao K Nakanishi M, Harada M, Kishimoto I, Kuwahara K, Kawakami R, Nakagawa Y, Yasuno S, Usami S, Kinoshita H, Adachi Y, Fukamizu A, Saito Y, Nakao K Nakanishi M, Harada M, Kishimoto I, Kuwahara K, Kawakami R, Nakagawa Y, Yasuno S, Usami S, Kinoshita H, Adachi Y, Fukamizu A, Saito Y, Nakao K Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation. Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation. Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation. Circulation journal : official journal of the Japanese Circulation Society, 71, 8, 1310-1316 Circulation journal : official journal of the Japanese Circulation Society, 71, 8, 1310-1316 Circulation journal : official journal of the Japanese Circulation Society, 71, 8, 1310-1316 2007/08 有 公開
Nakanishi M, Harada M, Tadamura E, Kotani H, Kawakami R, Kuwahara K, Nakagawa Y, Usami S, Kinoshita H, Fujiwara M, Hosoda K, Ueshima K, Nakao K Nakanishi M, Harada M, Tadamura E, Kotani H, Kawakami R, Kuwahara K, Nakagawa Y, Usami S, Kinoshita H, Fujiwara M, Hosoda K, Ueshima K, Nakao K Nakanishi M, Harada M, Tadamura E, Kotani H, Kawakami R, Kuwahara K, Nakagawa Y, Usami S, Kinoshita H, Fujiwara M, Hosoda K, Ueshima K, Nakao K Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance. Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance. Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance. Circulation, 116, 2, e25-6 Circulation, 116, 2, e25-6 Circulation, 116, 2, e25-6 2007/07 有 公開
Nakagawa Y, Kuwahara K, Harada M, Takahashi N, Yasuno S, Adachi Y, Kawakami R, Nakanishi M, Tanimoto K, Usami S, Kinoshita H, Saito Y, Nakao K Nakagawa Y, Kuwahara K, Harada M, Takahashi N, Yasuno S, Adachi Y, Kawakami R, Nakanishi M, Tanimoto K, Usami S, Kinoshita H, Saito Y, Nakao K Nakagawa Y, Kuwahara K, Harada M, Takahashi N, Yasuno S, Adachi Y, Kawakami R, Nakanishi M, Tanimoto K, Usami S, Kinoshita H, Saito Y, Nakao K Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes. Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes. Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes. Journal of molecular and cellular cardiology, 41, 6, 1010-1022 Journal of molecular and cellular cardiology, 41, 6, 1010-1022 Journal of molecular and cellular cardiology, 41, 6, 1010-1022 2006/12 有 公開
Tanimoto K, Saito Y, Hamanaka I, Kuwahara K, Harada M, Takahashi N, Kawakami R, Nakagawa Y, Nakanishi M, Adachi Y, Shirakami G, Fukuda K, Yoshimura A, Nakao K Tanimoto K, Saito Y, Hamanaka I, Kuwahara K, Harada M, Takahashi N, Kawakami R, Nakagawa Y, Nakanishi M, Adachi Y, Shirakami G, Fukuda K, Yoshimura A, Nakao K Tanimoto K, Saito Y, Hamanaka I, Kuwahara K, Harada M, Takahashi N, Kawakami R, Nakagawa Y, Nakanishi M, Adachi Y, Shirakami G, Fukuda K, Yoshimura A, Nakao K SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo. SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo. SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo. Circulation journal : official journal of the Japanese Circulation Society, 69, 11, 1412-1417 Circulation journal : official journal of the Japanese Circulation Society, 69, 11, 1412-1417 Circulation journal : official journal of the Japanese Circulation Society, 69, 11, 1412-1417 2005/11 有 公開
Nakanishi M, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakagawa Y, Tanimoto K, Yasuno S, Usami S, Li Y, Adachi Y, Fukamizu A, Garbers DL, Nakao K Nakanishi M, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakagawa Y, Tanimoto K, Yasuno S, Usami S, Li Y, Adachi Y, Fukamizu A, Garbers DL, Nakao K Nakanishi M, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakagawa Y, Tanimoto K, Yasuno S, Usami S, Li Y, Adachi Y, Fukamizu A, Garbers DL, Nakao K Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice. Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice. Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice. Hypertension, 46, 2, 441-447 Hypertension, 46, 2, 441-447 Hypertension, 46, 2, 441-447 2005/08 有 公開
Takahashi N, Saito Y, Kuwahara K, Harada M, Tanimoto K, Nakagawa Y, Kawakami R, Nakanishi M, Yasuno S, Usami S, Yoshimura A, Nakao K Takahashi N, Saito Y, Kuwahara K, Harada M, Tanimoto K, Nakagawa Y, Kawakami R, Nakanishi M, Yasuno S, Usami S, Yoshimura A, Nakao K Takahashi N, Saito Y, Kuwahara K, Harada M, Tanimoto K, Nakagawa Y, Kawakami R, Nakanishi M, Yasuno S, Usami S, Yoshimura A, Nakao K Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. Journal of molecular and cellular cardiology, 38, 1, 185-192 Journal of molecular and cellular cardiology, 38, 1, 185-192 Journal of molecular and cellular cardiology, 38, 1, 185-192 2005/01 有 公開
Kawakami R, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Nakagawa Y, Nakanishi M, Tanimoto K, Usami S, Yasuno S, Kinoshita H, Chusho H, Tamura N, Ogawa Y, Nakao K Kawakami R, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Nakagawa Y, Nakanishi M, Tanimoto K, Usami S, Yasuno S, Kinoshita H, Chusho H, Tamura N, Ogawa Y, Nakao K Kawakami R, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Nakagawa Y, Nakanishi M, Tanimoto K, Usami S, Yasuno S, Kinoshita H, Chusho H, Tamura N, Ogawa Y, Nakao K Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction. Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction. Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction. Circulation, 110, 21, 3306-3312 Circulation, 110, 21, 3306-3312 Circulation, 110, 21, 3306-3312 2004/11 有 公開
Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Hamanaka I, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Hamanaka I, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Hamanaka I, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. Endocrinology, 145, 2, 951-958 Endocrinology, 145, 2, 951-958 Endocrinology, 145, 2, 951-958 2004/02 有 公開
Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. The EMBO journal, 22, 23, 6310-6321 The EMBO journal, 22, 23, 6310-6321 The EMBO journal, 22, 23, 6310-6321 2003/12 有 公開
Takahashi N, Saito Y, Kuwahara K, Harada M, Kishimoto I, Ogawa Y, Kawakami R, Nakagawa Y, Nakanishi M, Nakao K Takahashi N, Saito Y, Kuwahara K, Harada M, Kishimoto I, Ogawa Y, Kawakami R, Nakagawa Y, Nakanishi M, Nakao K Takahashi N, Saito Y, Kuwahara K, Harada M, Kishimoto I, Ogawa Y, Kawakami R, Nakagawa Y, Nakanishi M, Nakao K Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation. Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation. Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation. Hypertension research : official journal of the Japanese Society of Hypertension, 26, 10, 847-853 Hypertension research : official journal of the Japanese Society of Hypertension, 26, 10, 847-853 Hypertension research : official journal of the Japanese Society of Hypertension, 26, 10, 847-853 2003/10 有 公開
Adachi Y, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakanishi M, Nakagawa Y, Tanimoto K, Saitoh Y, Yasuno S, Usami S, Iwai M, Horiuchi M, Nakao K Adachi Y, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakanishi M, Nakagawa Y, Tanimoto K, Saitoh Y, Yasuno S, Usami S, Iwai M, Horiuchi M, Nakao K Adachi Y, Saito Y, Kishimoto I, Harada M, Kuwahara K, Takahashi N, Kawakami R, Nakanishi M, Nakagawa Y, Tanimoto K, Saitoh Y, Yasuno S, Usami S, Iwai M, Horiuchi M, Nakao K Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice. Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice. Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice. Circulation, 107, 19, 2406-2408 Circulation, 107, 19, 2406-2408 Circulation, 107, 19, 2406-2408 2003/05 有 公開
Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Li Y, Kishimoto I, Saito Y, Harada M, Kuwahara K, Izumi T, Takahashi N, Kawakami R, Tanimoto K, Nakagawa Y, Nakanishi M, Adachi Y, Garbers DL, Fukamizu A, Nakao K Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart. Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart. Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart. Circulation, 106, 13, 1722-1728 Circulation, 106, 13, 1722-1728 Circulation, 106, 13, 1722-1728 2002/09 有 公開
K. Kuwahara; Y. Saito; E. Ogawa; N. Takahashi; Y. Nakagawa; Y. Naruse; M. Harada; I. Hamanaka; T. Izumi; Y. Miyamoto; I. Kishimoto; R. Kawakami; M. Nakanishi; N. Mori; K. Nakao K. Kuwahara; Y. Saito; E. Ogawa; N. Takahashi; Y. Nakagawa; Y. Naruse; M. Harada; I. Hamanaka; T. Izumi; Y. Miyamoto; I. Kishimoto; R. Kawakami; M. Nakanishi; N. Mori; K. Nakao The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes Molecular and Cellular Biology, 21, 6, 2085-2097 , 21, 6, 2085-2097 Molecular and Cellular Biology, 21, 6, 2085-2097 2001/03 有 英語 公開

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学術賞等
賞の名称(日本語) 賞の名称(英語) 授与組織名(日本語) 授与組織名(英語) 年月
日本臨床分子医学会学術集会学術奨励賞 日本臨床分子医学会 Japanese Society Molecular Medicine 2005/07/
日本心血管内分泌代謝学会YIA 日本心血管内分泌代謝学会 The Society of Cardiovascular Endocrinology and Metabolism 2006/11/
日本心不全学会優秀ポスター演題賞 日本心不全学会 The Japanese Heart Failure Society 2007/09/10
Scientific Session Poster Competition Best Science Award Scientific Session Poster Competition Best Science Award アメリカ心臓協会 American Heart Association 2007/11/06
研究奨励最優秀賞 国際心血管薬物療法学会日本部会 Japan section for International Society of Cardiovascular Pharmacotherapy 2016/06/26
外部資金：競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究（Ｃ） 酸化ストレス感受性カルシウムチャネルＴＲＰＭ２の心不全発症における意義の解明 2010〜2012
基盤研究（Ｃ） 代表 BNPプロセシング機序における糖鎖修飾の病態生理学的意義の解明 2013〜2015
基盤研究（Ｃ） 代表 BNPプロセシング機序における糖鎖修飾の病態生理学的意義の解明 （平成26年度分） 2014/04/01〜2015/03/31
基盤研究（Ｃ） 代表 BNPプロセシング機序における糖鎖修飾の病態生理学的意義の解明 （平成27年度分） 2015/04/01〜2016/03/31
基盤研究(C) 代表 O型糖転移酵素GALNTによる低活性型proBNP糖鎖修飾及び分泌制御機構の解明 2016/04/01〜2019/03/31
基盤研究(C) 代表 O型糖転移酵素GALNTによる低活性型proBNP糖鎖修飾及び分泌制御機構の解明 （平成28年度分） 2016/04/01〜2017/03/31
基盤研究(C) 代表 O型糖転移酵素GALNTによる低活性型proBNP糖鎖修飾及び分泌制御機構の解明 （平成30年度分） 2018/04/01〜2019/03/31
基板研究C 代表 proBNPの糖鎖修飾制御機構の解明に基づく心疾患の新規診断法・治療法の開発 2019/04/01〜2012/03/31
外部資金：競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
武田科学振興財団　医学系研究奨励（生活習慣病） 中川靖章 ヒストンアセチル化酵素の心筋ミトコンドリア形成と細胞生存維持における役割の解明 2011/04/01〜2012/03/31
部局運営（役職等）
役職名 期間
動物実験施設運営委員会 2013/04/01〜2014/03/31

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