Distinct Cell Surface Expression Patterns of N-Glycosylation Site Mutants of AMPA-Type Glutamate Receptor under the Homo-Oligomeric Expression Conditions.
International journal of molecular sciences, 2020年07月19日
Monitoring the glycosylation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones in mice.
AMPA receptors in the synapse turnover by monomer diffusion.
Jyoji Morise; Kenichi G N Suzuki; Ayaka Kitagawa; Yoshihiko Wakazono; Kogo Takamiya; Taka A Tsunoyama; Yuri L Nemoto; Hiromu Takematsu; Akihiro Kusumi; Shogo Oka
Glycoscience: Basic Science to Applications: Insights from the Japan Consortium for Glycobiology and Glycotechnology (JCGG), 2019年01月01日
Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1.
The role of human natural killer-1 (HNK-1) carbohydrate in neuronal plasticity and disease.
Morise J; Takematsu H; Oka S
Biochimica et biophysica acta, 2017年10月, 査読有り
MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts.
[Dystroglycan glycosylation: structure, synthetic pathway, and in vivo role in the brain development].
Naoki Nakagawa; Shogo Oka
Seikagaku. The Journal of Japanese Biochemical Society, 2016年08月, 査読有り
Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow.
Loss of α1,6-Fucosyltransferase Decreases Hippocampal Long Term Potentiation: IMPLICATIONS FOR CORE FUCOSYLATION IN THE REGULATION OF AMPA RECEPTOR HETEROMERIZATION AND CELLULAR SIGNALING.
Gu W; Fukuda T; Isaji T; Hang Q; Lee HH; Sakai S; Morise J; Mitoma J; Higashi H; Taniguchi N; Yawo H; Oka S, Gu J
The Journal of biological chemistry, 2015年07月10日, 査読有り
Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy.
Naoki Nakagawa; Hirokazu Yagi; Koichi Kato; Hiromu Takematsu; Shogo Oka
Human natural killer-1 sulfotransferase (HNK-1ST)-induced sulfate transfer regulates laminin-binding glycans on α-dystroglycan
N. Nakagawa; H. Manya; T. Toda; T. Endo; S. Oka
Journal of Biological Chemistry, 2012年08月, 査読有り
Role of interaction of mannan-binding protein with meprins at the initial step of complement activation in ischemia/reperfusion injury to mouse kidney
Makoto Hirano; Bruce Y. Ma; Nobuko Kawasaki; Shogo Oka; Toshisuke Kawasaki
GLYCOBIOLOGY, 2012年01月, 査読有り
Sulfation of glucuronic acid in the linkage tetrasaccharide by HNK-1 sulfotransferase is an inhibitory signal for the expression of a chondroitin sulfate chain on thrombomodulin
Naoki Nakagawa; Tomomi Izumikawa; Hiroshi Kitagawa; Shogo Oka
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011年11月, 査読有り
Specific Enzyme Complex of beta-1,4-Galactosyltransferase-II and Glucuronyltransferase-P Facilitates Biosynthesis of N-linked Human Natural Killer-1 (HNK-1) Carbohydrate
Specific enzyme complex of β-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate
T. Kouno; Y. Kizuka; N. Nakagawa; T. Yoshihara; M. Asano; S. Oka
Journal of Biological Chemistry, 2011年09月, 査読有り
HNK-1糖鎖抗原と神経突起の形成
中川直樹; 森田一平; 岡 昌吾
脳21, 14(1), 37-43, 2011年
HNK-1糖鎖によるグルタミン酸受容体の発現レベルの調節
森瀬譲二; 森田一平; 岡 昌吾
生化学 83(3), 205-211, 2011年
Requirement of acidic amino acids in the Glucuronyltransferase-P (GlcAT-P) flexible loop for its enzyme activity.
Y. Kizuka; N. Nakagawa; I. Morita; S. Oka
Glycans: Biochemistry, Characterization and Applications, 2011年, 査読有り
Learning/memory impairment and reduced expression of the HNK-1 carbohydrate in β4-galactosyltransferase-II-deficient mice
T. Yoshihara; K. Sugihara; Y. Kizuka; S. Oka; M. Asano
Journal of Biological Chemistry, 2009年05月, 査読有り
Distinct Transport and Intracellular Activities of Two GlcAT-P Isoforms
Yasuhiko Kizuka; Yasuhiro Tonoyama; Shogo Oka
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009年04月, 査読有り
Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116
Development and application of high performance liquid chromatography map of glucuronyl N-glycans.
H. Yagi; K. Yamada; E. Ohno; M. Utsumi; Y. Yamaguchi; E. Kurimoto; N. Takahashi; S. Oka; T. Kawasaki; K. Kato
Open Glycoscience, 1, 8-18, 2008年, 査読有り
Distributions of glucuronyltransferases, GlcAT-P and GlcAT-S, and their target substrate, the HNK-1 carbohydrate epitope in the adult mouse brain with or without a targeted deletion of the GlcAT-P gene
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2006年11月, 査読有り
Physical and functional association of glucuronyltransferases and sulfotransferase involved in HNK-1 biosynthesis
Y Kizuka; T Matsui; H Takematsu; Y Kozutsumi; T Kawasaki; S Oka
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006年05月, 査読有り
Mannan-binding protein blocks the activation of metalloproteases meprin α and β
M. Hirano; B.Y. Ma; N. Kawasaki; K. Okimura; M. Baba; T. Nakagawa; K. Miwa; N. Kawasaki; S. Oka; T. Kawasaki
Journal of Immunology, 2005年09月, 査読有り
記憶学習機能における糖鎖修飾の関与
岡 昌吾; 角田品子; 川嵜敏祐
生化学, 2005年06月25日
A non-sulfated form of the HNK-1 carbohydrate is expressed in mouse kidney
H Tagawa; Y Kizuka; T Ikeda; S Itoh; N Kawasaki; H Kurihara; ML Onozato; A Tojo; T Sakai; T Kawasaki; S Oka
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005年06月, 査読有り
Involvement of carbohydrate-modification in learning and memory
S Oka; S Kakuda; T Kawasaki
SEIKAGAKU, 2005年06月, 査読有り
Characterization of oligosaccharide ligands expressed on SW1116 cells recognized by mannan-binding protein - A highly fucosylated polylactosamine type N-glycan
M Terada; KH Khoo; R Inoue; CI Chen; K Yamada; H Sakaguchi; N Kadowaki; BY Ma; S Oka; T Kawasaki; N Kawasaki
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005年03月, 査読有り
Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate
Structural basis for acceptor substrate recognition of a human glucuronyltransferase, GlcAT-P, an enzyme critical in the biosynthesis of the carbohydrate epitope HNK-1
S Kakuda; T Shiba; M Ishiguro; H Tagawa; S Oka; Y Kajihara; T Kawasaki; S Wakatsuki; R Kato
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004年05月, 査読有り
Purification and characterization of two recombinant human glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate in Escherichia coli
S Kakuda; S Oka; T Kawasaki
PROTEIN EXPRESSION AND PURIFICATION, 2004年05月, 査読有り
神経系ネットワーク形成における糖鎖シグナルの役割
井上満博; 岡 昌吾; 川嵜敏祐
実験医学,22巻 946-950, 2004年
Superoxide production from human polymorphonuclear leukocytes by human mannan-binding protein (MBP)
K Uemura; H Yamamoto; T Nakagawa; K Nakamura; N Kawasaki; S Oka; BY Ma; T Kawasaki
GLYCOCONJUGATE JOURNAL, 2004年, 査読有り
Role of mannan-binding protein, MBP, in innate immunity
T Nakagawa; BY Ma; K Uemura; S Oka; N Kawasaki; T Kawasaki
ANTICANCER RESEARCH, 2003年11月, 査読有り
疾患との関連,治療への応用 レクチン経路の癌免疫への応用
沖村一満; 岡昌吾; 川崎敏祐
医学のあゆみ, 2003年04月05日
Mixed lineage kinase LZK and antioxidant protein-1 activate NF-κB synergistically
M. Masaki; A. Ikeda; E. Shiraki; S. Oka; T. Kawasaki
European Journal of Biochemistry, 2003年01月, 査読有り
Involvement of acidic carbohydrates in learning and memory
CDNA cloning, genomic structure and chromosomal mapping of the mouse glucuronyltransferase-S involved in the biosynthesis of the HNK-1 carbohydrate epitope
K Imiya; T Ishizaki; T Seiki; F Saito; J Inazawa; S Oka; T Kawasaki
GENE, 2002年08月, 査読有り
Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning
S Yamamoto; S Oka; M Inoue; M Shimuta; T Manabe; M Takahashi; M Miyamoto; M Asano; J Sakagami; K Sudo; Y Iwakura; K Ono; T Kawasaki
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002年07月, 査読有り
Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene
A. Ikeda; H. Sakuma; M. Masaki; Y. Kozutsumi; S. Oka; J. Inazawa; T. Kawasaki
Journal of Biochemistry, Molecular Biology and Biophysics, 2002年04月, 査読有り
Molecular cloning and genomic analysis of mouse glucuronyltransferase involved in biosynthesis of the HNK-1 epitope
S Yamamoto; S Oka; F Saito-Ohara; J Inazawa; T Kawasaki
JOURNAL OF BIOCHEMISTRY, 2002年03月, 査読有り
Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH2-terminal kinase pathway
A Ikeda; K Hasegawa; M Masaki; T Moriguchi; E Nishida; Y Kozutsumi; S Oka; T Kawasaki
JOURNAL OF BIOCHEMISTRY, 2001年12月, 査読有り
神経系特異的糖鎖抗原HNK-1の役割
岡 昌吾; 川嵜敏祐
日本神経精神薬理学雑誌 = Japanese journal of psychopharmacology, 2001年09月25日
Glucuronyltransferases involved in the HNK-1 carbohydrate epitope biosynthesis
S Yamamoto; S Oka
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, 2001年03月, 査読有り
Expression of macrophage asialoglycoprotein-binding protein is induced through MAPK classical pathway
R Katsuyama; A Morioka; S Oka; T Kawasaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001年02月, 査読有り
Identification and characterization of functional domains in a mixed lineage kinase LZK
A Ikeda; M Masaki; Y Kozutsumi; S Oka; T Kawasaki
FEBS LETTERS, 2001年01月, 査読有り
Roles of the HNK-1 carbohydrate epitope in the nervous system
T. Kawasaki; S. Oka
Japanese Journal of Psychopharmacology, 2001年, 査読有り
神経系における糖鎖の役割糖鎖リモデリングによるHNK-1糖質の解析を中心に
川嵜敏祐; 岡 昌吾
細胞工学,20/2,187-192, 2001年
The N-glycan acceptor specificity of a glucuronyltransferase, GlcAT-P, associated with biosynthesis of the HNK-1 epitope
S Oka; K Terayama; K Imiya; S Yamamoto; A Kondo; Kato, I; T Kawasaki
GLYCOCONJUGATE JOURNAL, 2000年12月, 査読有り
Studies on the structure-function relationship of the HNK-1 associated glucuronyltransferase, GlcAT-P, by computer modeling and site-directed mutagenesis
K Ohtsubo; S Imajo; M Ishiguro; T Nakatani; S Oka; T Kawasaki
JOURNAL OF BIOCHEMISTRY, 2000年08月, 査読有り
Cloning and chromosomal mapping of human glucuronyltransferase involved in biosynthesis of the HNK-1 carbohydrate epitope
Y Mitsumoto; S Oka; H Sakuma; J Inazawa; T Kawasaki
GENOMICS, 2000年04月, 査読有り
Characterization of human serum mannan-binding protein promoter
H Naito; A Ikeda; K Hasegawa; S Oka; K Uemura; N Kawasaki; T Kawasaki
JOURNAL OF BIOCHEMISTRY, 1999年12月, 査読有り
Characterization of recombinant human glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans
Y Tone; H Kitagawa; K Imiya; S Oka; T Kawasaki; K Sugahara
FEBS LETTERS, 1999年10月, 査読有り
細胞接着分子に発現するHNK-1糖鎖抗原の生物学的機能 (特集 糖鎖硫酸基のバイオシグナリング)
岡 昌吾; 川嵜 敏祐
細胞工学, 1999年03月
Molecular cloning and expression of a second glucuronyltransferase involved in the biosynthesis of the HNK-1 carbohydrate epitope
T Seiki; S Oka; K Terayama; K Imiya; T Kawasaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999年02月, 査読有り
Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: Mannan-binding protein-dependent cell-mediated cytotoxicity
Y Ma; K Uemura; S Oka; Y Kozutsumi; N Kawasaki; T Kawasaki
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999年01月, 査読有り
Purification and characterization of a glucuronyltransferase involved in the biosynthesis of the HNK-1 epitope on glycoproteins from rat brain
K Terayama; T Seiki; A Nakamura; K Matsumori; S Ohta; S Oka; M Sugita; T Kawasaki
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998年11月, 査読有り
Molecular biological approach to functions of telencephalin, a cell adhesion molecule and HNK-1 carbohydrate epitope, which is commonly expressed on cell adhesion molecules in the nervous system
S Oka
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1998年10月, 査読有り
Biological functions of the neural specific carbohydrate antigen, HNK-1
T Kawasaki; S Oka; K Terayama; T Seiki; A Nakamura; Y Mitumoto; K Ohtsubo; S Yamamoto
FASEB JOURNAL, 1998年04月, 査読有り
Molecular cloning and expression of glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans
H Kitagawa; Y Tone; J Tamura; KW Neumann; T Ogawa; S Oka; T Kawasaki; K Sugahara
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998年03月, 査読有り
Biological roles of HNK-1 carbohydrate epitope in the nervous system
AMPA型グルタミン酸受容体の糖鎖修飾解析から明らかになったN型糖鎖修飾部位への分子シャペロン結合という新規制御メカニズム(Monitoring the glycosylation of AMPA-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones)
緑川 良介; 高倉 大輔; 森瀬 譲二; 川崎 ナナ; 岡 昌吾; 高宮 考悟
日本生化学会大会プログラム・講演要旨集, 2019年09月
腎障害に伴った非硫酸化型HNK-1糖鎖抗原の腎臓内発現変化と早期疾患マーカーとしての可能性の解析
森瀬 譲二; 北野 仁望; 岡 昌吾
臨床化学, 2019年08月
サイコシンによるエンドマイトーシス誘導機構の解明
井谷 有希; 渡邉 寛; 岡 昌吾; 竹松 弘
日本生化学会大会プログラム・講演要旨集, 2018年09月
ヒト特異的に生じる異種自己抗原に対する免疫応答のマウスモデル樹立
佐藤 弓奈; 中島 英規; Laine Roger A.; 岡 昌吾; 竹松 弘
日本生化学会大会プログラム・講演要旨集, 2018年09月
糖尿病性腎症に伴う腎臓内の非硫酸化型HNK-1糖鎖発現変化の解析
北野 仁望; 森瀬 譲二; 岡 昌吾
臨床化学, 2018年07月
抗MAG抗体ニューロパチーにおける抗体affinityと臨床経過の比較
松井 太郎; 濱田 征宏; 桑原 基; 森瀬 譲二; 岡 昌吾; 楠 進
末梢神経, 2017年12月
抗MAG抗体ニューロパチーにおける抗体affinityと臨床経過の比較
松井 太郎; 濱田 征宏; 桑原 基; 森瀬 譲二; 岡 昌吾; 楠 進
末梢神経, 2017年12月
The role of human natural killer-1 (HNK-1) carbohydrate in neuronal plasticity and disease.
Jyoji Morise; Hiromu Takematsu; Shogo Oka
Biochimica et biophysica acta. General subjects, 2017年10月, 査読有り
Relative hypercoagulation induced by suppressed fibrinolysis after tisagenlecleucel infusion in malignant lymphoma(悪性リンパ腫に対するチサゲンレクルユーセル投与後に見られる線溶抑制および相対的凝固亢進状態)