佐々木 努

最終更新日時: 2019/08/28 21:50:18

印刷する

氏名(漢字／フリガナ／アルファベット表記)
佐々木 努／ササキ ツトム／Sasaki, Tsutomu
所属部署・職名(部局／所属／講座等／職名)
農学研究科／食品生物科学専攻食品健康科学講座／教授
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8502　京都市左京区北白川追分町 Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto 606-8502, JAPAN
所属学会(国内)
学会名(日本語) 学会名(英語)
日本内分泌学会 Japan Endocrine Society
日本肥満学会 Japan Society for the Study of Obesity
日本生理学会 Physiological Society of Japan
日本糖尿病学会 Japan Diabetes Society
日本神経科学学会 Japan Neuroscience Society
日本分子生物学会 Molecular Biology Society of Japan
日本栄養・食糧学会 Japan Society of Nutrition and Food Science
日本農芸化学会 Japan Society for Bioscience, Biotechnology, and Agrochemistry
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
Ph. D. in Neuroscience PhD in Neuroscience バージニア大学 University of Virginia
出身大学院・研究科等
大学名(日本語) 大学名(英語) 研究科名(日本語) 研究科名(英語) 専攻名(日本語) 専攻名(英語) 修了区分
バージニア大学 University of Virginia 大学院神経科学科博士課程 Neuroscience Graduate Program 修了
出身学校・専攻等
大学名(日本語) 大学名(英語) 学部名(日本語) 学部名(英語) 学科名(日本語) 学科名(英語) 卒業区分
東京大学 University of Tokyo 医学部医学科 School of Medicine 卒業
出身高等学校
高等学校名 ふりがな
成蹊高校 せいけいこうこう
職歴
期間 組織名(日本語) 組織名(英語) 職名(日本語) 職名(英語)
1998/07/01〜1999/06/30 Dept of Neurosurgery, University of Virginia Hospital 一般フェロー General Fellow
1999/07/01〜2000/06/30 Dept of Surgery, University of Virginia Hospital インターン Intern
2000/07/01〜2002/12/31 Dept of Neurosurgery, University of Virginia Hospital レジデント Resident Physician
2007/11/1〜2013/03/31 群馬大学生体調節研究所代謝シグナル解析分野 Lab of Metabolic Signal, IMCR, Gunma University 助教 Assistant Professor
2013/04/01〜2019/03/31 群馬大学生体調節研究所代謝シグナル解析分野 Lab of Metabolic Signal, IMCR, Gunma University 准教授 Associate Professor
2019/04/01〜 京都大学大学院農学研究科食品生物科学専攻栄養化学分野 Div. of Food Science and Biotechnology, Grad School of Agriculture, Kyoto University 教授 Professor
使用言語
言語名(japanese) 言語名(english) コード
日本語
英語
個人ホームページ
URL
http://www.nutrchem.kais.kyoto-u.ac.jp/personal_history.html
ORCID ID
https://orcid.org/0000-0001-8041-1915
researchmap URL
https://researchmap.jp/read0145909
研究テーマ
(日本語)
食行動の制御メカニズムの解明
(英語)
Deciphering the mechanisms that control eating behavior
研究概要
(日本語)
食行動の制御メカニズム（しくみ）の全容解明をめざしています。そのために、神経科学・内分泌代謝学・分子生物学・遺伝学など、生命科学のアプローチを幅広く取り入れ、弾力的に取り組んでいます。
(英語)
We are working on completely elucidating the mechanisms that control eating behavior. To achieve the goal, we incorporate various techniques used in biological sciences, such as neuroscience, endocrinology, molecular biology, genetics.
研究分野（キーワード）
キーワード(日本語) キーワード(英語)
食欲 Appetite
食行動 Feeding behavior
生体恒常性 homeostasis
臓器連関 Inter-organ communication
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Takayoshi Suga, Osamu Kikuchi, Masaki Kobayashi, Sho Matsui, Hiromi Yokota-Hashimoto, Eri Wada, Daisuke Kohno, Tsutomu Sasaki, Kazusane Takeuchi, Satoru Kakizaki, Masanobu Yamada, Tadahiro Kitamura Takayoshi Suga, Osamu Kikuchi, Masaki Kobayashi, Sho Matsui, Hiromi Yokota-Hashimoto, Eri Wada, Daisuke Kohno, Tsutomu Sasaki, Kazusane Takeuchi, Satoru Kakizaki, Masanobu Yamada, Tadahiro Kitamura Takayoshi Suga, Osamu Kikuchi, Masaki Kobayashi, Sho Matsui, Hiromi Yokota-Hashimoto, Eri Wada, Daisuke Kohno, Tsutomu Sasaki, Kazusane Takeuchi, Satoru Kakizaki, Masanobu Yamada, Tadahiro Kitamura SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels Molecular Metabolism, 19, 1-12 Molecular Metabolism, 19, 1-12 Molecular Metabolism, 19, 1-12 2019/01 有 英語 研究論文(学術雑誌) 公開
Matsui S, Sasaki T*, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Matsui S, Sasaki T*, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Matsui S, Sasaki T*, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice Nature Communications Nature Communications Nature Communications 2018/11 有 英語 研究論文(学術雑誌) 公開
Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. Aging Cell Aging Cell Aging Cell 2018/06 有 公開
Tsutomu Sasaki, Rika Numano, Hiromi Yokota-Hashimoto, Sho Matsui, Naobumi Kimura, Hideyuki Takeuchi, Tadahiro Kitamura Tsutomu Sasaki, Rika Numano, Hiromi Yokota-Hashimoto, Sho Matsui, Naobumi Kimura, Hideyuki Takeuchi, Tadahiro Kitamura Tsutomu Sasaki, Rika Numano, Hiromi Yokota-Hashimoto, Sho Matsui, Naobumi Kimura, Hideyuki Takeuchi, Tadahiro Kitamura A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice Molecular Brain, 11, 1, 28 Molecular Brain, 11, 1, 28 Molecular Brain, 11, 1, 28 2018/05 有 英語 研究論文(学術雑誌) 公開
Tsutomu Sasaki Tsutomu Sasaki Tsutomu Sasaki Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns Neural and Molecular Mechanisms Involved in Controlling the Quality of Feeding Behavior: Diet Selection and Feeding Patterns Nutrients, 9, 10, 1151 Nutrients, 9, 10, 1151 Nutrients, 9, 10, 1151 2017/10 有 公開
Ishimaru, Yoshiro; Kozuka, Chisayo; Nakajima, Kenichiro; Sasaki, Tsutomu Ishimaru, Yoshiro; Kozuka, Chisayo; Nakajima, Kenichiro; Sasaki, Tsutomu Ishimaru, Yoshiro; Kozuka, Chisayo; Nakajima, Kenichiro; Sasaki, Tsutomu Expanding frontiers in weight-control research explored by young investigators Expanding frontiers in weight-control research explored by young investigators Expanding frontiers in weight-control research explored by young investigators JOURNAL OF PHYSIOLOGICAL SCIENCES, 67, 1, 83-95 JOURNAL OF PHYSIOLOGICAL SCIENCES, 67, 1, 83-95 JOURNAL OF PHYSIOLOGICAL SCIENCES, 67, 1, 83-95 2017 公開
Fukunaka, Ayako; Fukada, Toshiyuki; Bhin, Jinhyuk; Suzuki, Luka; Tsuzuki, Takamasa; Takamine, Yuri; Bin, Bum-Ho; Yoshihara, Toshinori; Ichinoseki-Sekine, Noriko; Naito, Hisashi; Miyatsuka, Takeshi; Takamiya, Shinzaburo; Sasaki, Tsutomu; Inagaki, Takeshi; Kitamura, Tadahiro; Kajimura, Shingo; Watada, Hirotaka; Fujitani, Yoshio Fukunaka, Ayako; Fukada, Toshiyuki; Bhin, Jinhyuk; Suzuki, Luka; Tsuzuki, Takamasa; Takamine, Yuri; Bin, Bum-Ho; Yoshihara, Toshinori; Ichinoseki-Sekine, Noriko; Naito, Hisashi; Miyatsuka, Takeshi; Takamiya, Shinzaburo; Sasaki, Tsutomu; Inagaki, Takeshi; Kitamura, Tadahiro; Kajimura, Shingo; Watada, Hirotaka; Fujitani, Yoshio Fukunaka, Ayako; Fukada, Toshiyuki; Bhin, Jinhyuk; Suzuki, Luka; Tsuzuki, Takamasa; Takamine, Yuri; Bin, Bum-Ho; Yoshihara, Toshinori; Ichinoseki-Sekine, Noriko; Naito, Hisashi; Miyatsuka, Takeshi; Takamiya, Shinzaburo; Sasaki, Tsutomu; Inagaki, Takeshi; Kitamura, Tadahiro; Kajimura, Shingo; Watada, Hirotaka; Fujitani, Yoshio Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-beta expression Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-beta expression Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-beta expression PLOS GENETICS, 13, 8, e1006950 PLOS GENETICS, 13, 8, e1006950 PLOS GENETICS, 13, 8, e1006950 2017 公開
Sasaki, Tsutomu; Yasoshima, Yasunobu; Matsui, Sho; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Kitamura, Tadahiro Sasaki, Tsutomu; Yasoshima, Yasunobu; Matsui, Sho; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Kitamura, Tadahiro Sasaki, Tsutomu; Yasoshima, Yasunobu; Matsui, Sho; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Kitamura, Tadahiro Intraperitoneal injection of d-serine inhibits high-fat diet intake and preference in male mice. Intraperitoneal injection of d-serine inhibits high-fat diet intake and preference in male mice. Intraperitoneal injection of d-serine inhibits high-fat diet intake and preference in male mice. APPETITE, 118, 120-128 APPETITE, 118, 120-128 APPETITE, 118, 120-128 2017 有 公開
Iwakoshi-Ukena, Eiko; Shikano, Kenshiro; Kondo, Kunihiro; Taniuchi, Shusuke; Furumitsu, Megumi; Ochi, Yuta; Sasaki, Tsutomu; Okamoto, Shiki; Bentley, George E.; Kriegsfeld, Lance J.; Minokoshi, Yasuhiko; Ukena, Kazuyoshi Iwakoshi-Ukena, Eiko; Shikano, Kenshiro; Kondo, Kunihiro; Taniuchi, Shusuke; Furumitsu, Megumi; Ochi, Yuta; Sasaki, Tsutomu; Okamoto, Shiki; Bentley, George E.; Kriegsfeld, Lance J.; Minokoshi, Yasuhiko; Ukena, Kazuyoshi Iwakoshi-Ukena, Eiko; Shikano, Kenshiro; Kondo, Kunihiro; Taniuchi, Shusuke; Furumitsu, Megumi; Ochi, Yuta; Sasaki, Tsutomu; Okamoto, Shiki; Bentley, George E.; Kriegsfeld, Lance J.; Minokoshi, Yasuhiko; Ukena, Kazuyoshi Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. ELIFE, 6, e28527 ELIFE, 6, e28527 ELIFE, 6, e28527 2017 有 公開
Sasaki, Tsutomu; Matsui, Sho; Kitamura, Tadahiro Sasaki, Tsutomu; Matsui, Sho; Kitamura, Tadahiro Sasaki, Tsutomu; Matsui, Sho; Kitamura, Tadahiro Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17, 7, 1081 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17, 7, 1081 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17, 7, 1081 2016 公開
佐々木 努 佐々木 努 佐々木 努 中枢神経系SIRT1による体重調節機構 中枢神経系SIRT1による体重調節機構 中枢神経系SIRT1による体重調節機構 内分泌・糖尿病・代謝内科, 41, 1, 14-18 内分泌・糖尿病・代謝内科, 41, 1, 14-18 内分泌・糖尿病・代謝内科, 41, 1, 14-18 2015 公開
佐々木 努 佐々木 努 佐々木 努 日米大学院教育の違いについて (特集 精神医学の未来を切り開く : 大学院教育はこれでよいのか(2)) 日米大学院教育の違いについて (特集 精神医学の未来を切り開く : 大学院教育はこれでよいのか(2)) 日米大学院教育の違いについて (特集 精神医学の未来を切り開く : 大学院教育はこれでよいのか(2)) 精神神経学雑誌, 117, 9, 737-742 精神神経学雑誌, 117, 9, 737-742 精神神経学雑誌, 117, 9, 737-742 2015 公開
Sasaki, Tsutomu Sasaki, Tsutomu Sasaki, Tsutomu Age-associated weight gain, leptin, and SIRT1: a possible role for hypothalamic SIRT1 in the prevention of weight gain and aging through modulation of leptin sensitivity Age-associated weight gain, leptin, and SIRT1: a possible role for hypothalamic SIRT1 in the prevention of weight gain and aging through modulation of leptin sensitivity Age-associated weight gain, leptin, and SIRT1: a possible role for hypothalamic SIRT1 in the prevention of weight gain and aging through modulation of leptin sensitivity FRONTIERS IN ENDOCRINOLOGY, 6, 109 FRONTIERS IN ENDOCRINOLOGY, 6, 109 FRONTIERS IN ENDOCRINOLOGY, 6, 109 2015 公開
Sasaki, Tsutomu; Kinoshita, Yoshihiro; Matsui, Sho; Kakuta, Shigeru; Yokota-Hashimoto, Hiromi; Kinoshita, Kuni; Iwasaki, Yusaku; Kinoshita, Toshio; Yada, Toshihiko; Amano, Naoji; Kitamura, Tadahiro Sasaki, Tsutomu; Kinoshita, Yoshihiro; Matsui, Sho; Kakuta, Shigeru; Yokota-Hashimoto, Hiromi; Kinoshita, Kuni; Iwasaki, Yusaku; Kinoshita, Toshio; Yada, Toshihiko; Amano, Naoji; Kitamura, Tadahiro Sasaki, Tsutomu; Kinoshita, Yoshihiro; Matsui, Sho; Kakuta, Shigeru; Yokota-Hashimoto, Hiromi; Kinoshita, Kuni; Iwasaki, Yusaku; Kinoshita, Toshio; Yada, Toshihiko; Amano, Naoji; Kitamura, Tadahiro N-methyl-D-aspartate receptor coagonist D-serine suppresses intake of high-preference food N-methyl-D-aspartate receptor coagonist D-serine suppresses intake of high-preference food N-methyl-D-aspartate receptor coagonist D-serine suppresses intake of high-preference food AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 309, 5, R561-R575 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 309, 5, R561-R575 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 309, 5, R561-R575 2015 公開
Sasaki, Tsutomu; Kuroko, Mitsutaka; Sekine, Sawako; Matsui, Sho; Kikuchi, Osamu; Susanti, Vina Yanti; Kobayashi, Masaki; Tanaka, Yoshinori; Yuasa, Tomoyuki; Kitamura, Tadahiro Sasaki, Tsutomu; Kuroko, Mitsutaka; Sekine, Sawako; Matsui, Sho; Kikuchi, Osamu; Susanti, Vina Yanti; Kobayashi, Masaki; Tanaka, Yoshinori; Yuasa, Tomoyuki; Kitamura, Tadahiro Sasaki, Tsutomu; Kuroko, Mitsutaka; Sekine, Sawako; Matsui, Sho; Kikuchi, Osamu; Susanti, Vina Yanti; Kobayashi, Masaki; Tanaka, Yoshinori; Yuasa, Tomoyuki; Kitamura, Tadahiro Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice ENDOCRINE JOURNAL, 62, 9, 787-796 ENDOCRINE JOURNAL, 62, 9, 787-796 ENDOCRINE JOURNAL, 62, 9, 787-796 2015 公開
Sasaki, Tsutomu; Hiraga, Haruna; Yokota-Hashimoto, Hiromi; Kitamura, Tadahiro Sasaki, Tsutomu; Hiraga, Haruna; Yokota-Hashimoto, Hiromi; Kitamura, Tadahiro Sasaki, Tsutomu; Hiraga, Haruna; Yokota-Hashimoto, Hiromi; Kitamura, Tadahiro Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue. Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue. Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue. ENDOCRINE JOURNAL, 62, 5, 469-473 ENDOCRINE JOURNAL, 62, 5, 469-473 ENDOCRINE JOURNAL, 62, 5, 469-473 2015 有 公開
Kohno, Daisuke; Lee, Syann; Harper, Matthew J.; Kim, Ki Woo; Sone, Hideyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Fan, Guoping; Elmquist, Joel K. Kohno, Daisuke; Lee, Syann; Harper, Matthew J.; Kim, Ki Woo; Sone, Hideyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Fan, Guoping; Elmquist, Joel K. Kohno, Daisuke; Lee, Syann; Harper, Matthew J.; Kim, Ki Woo; Sone, Hideyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Fan, Guoping; Elmquist, Joel K. Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis Dnmt3a in Sim1 Neurons Is Necessary for Normal Energy Homeostasis JOURNAL OF NEUROSCIENCE, 34, 46, 15288-15296 JOURNAL OF NEUROSCIENCE, 34, 46, 15288-15296 JOURNAL OF NEUROSCIENCE, 34, 46, 15288-15296 2014 公開
Usui, Taro; Kajita, Kazuo; Kajita, Toshiko; Mori, Ichiro; Hanamoto, Takayuki; Ikeda, Takahide; Okada, Hideyuki; Taguchi, Koichiro; Kitada, Yoshihiko; Morita, Hiroyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Sato, Takashi; Kojima, Itaru; Ishizuka, Tatsuo Usui, Taro; Kajita, Kazuo; Kajita, Toshiko; Mori, Ichiro; Hanamoto, Takayuki; Ikeda, Takahide; Okada, Hideyuki; Taguchi, Koichiro; Kitada, Yoshihiko; Morita, Hiroyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Sato, Takashi; Kojima, Itaru; Ishizuka, Tatsuo Usui, Taro; Kajita, Kazuo; Kajita, Toshiko; Mori, Ichiro; Hanamoto, Takayuki; Ikeda, Takahide; Okada, Hideyuki; Taguchi, Koichiro; Kitada, Yoshihiko; Morita, Hiroyuki; Sasaki, Tsutomu; Kitamura, Tadahiro; Sato, Takashi; Kojima, Itaru; Ishizuka, Tatsuo Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice. Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice. Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice. FEBS LETTERS, 588, 10, 1935-1941 FEBS LETTERS, 588, 10, 1935-1941 FEBS LETTERS, 588, 10, 1935-1941 2014 有 公開
Lee, Yong-Soo; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Susanti, Vina Yanti; Kitamura, Yukari Ido; Kitamura, Tadahiro Lee, Yong-Soo; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Susanti, Vina Yanti; Kitamura, Yukari Ido; Kitamura, Tadahiro Lee, Yong-Soo; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Susanti, Vina Yanti; Kitamura, Yukari Ido; Kitamura, Tadahiro ATF3 expression is induced by low glucose in pancreatic alpha and beta cells and regulates glucagon but not insulin gene transcription ATF3 expression is induced by low glucose in pancreatic alpha and beta cells and regulates glucagon but not insulin gene transcription ATF3 expression is induced by low glucose in pancreatic alpha and beta cells and regulates glucagon but not insulin gene transcription ENDOCRINE JOURNAL, 61, 1, 85-90 ENDOCRINE JOURNAL, 61, 1, 85-90 ENDOCRINE JOURNAL, 61, 1, 85-90 2014 公開
Sasaki, Tsutomu; Kikuchi, Osamu; Shimpuku, Mayumi; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Taguchi, Ryo; Shibusawa, Nobuyuki; Sato, Takashi; Tang, Lijun; Amano, Kosuke; Kitazumi, Tomoya; Kuroko, Mitsutaka; Fujita, Yuki; Maruyama, Jun; Lee, Yong-soo; Kobayashi, Masaki; Nakagawa, Takashi; Minokoshi, Yasuhiko; Harada, Akihiro; Yamada, Masanobu; Kitamura, Tadahiro Sasaki, Tsutomu; Kikuchi, Osamu; Shimpuku, Mayumi; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Taguchi, Ryo; Shibusawa, Nobuyuki; Sato, Takashi; Tang, Lijun; Amano, Kosuke; Kitazumi, Tomoya; Kuroko, Mitsutaka; Fujita, Yuki; Maruyama, Jun; Lee, Yong-soo; Kobayashi, Masaki; Nakagawa, Takashi; Minokoshi, Yasuhiko; Harada, Akihiro; Yamada, Masanobu; Kitamura, Tadahiro Sasaki, Tsutomu; Kikuchi, Osamu; Shimpuku, Mayumi; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Taguchi, Ryo; Shibusawa, Nobuyuki; Sato, Takashi; Tang, Lijun; Amano, Kosuke; Kitazumi, Tomoya; Kuroko, Mitsutaka; Fujita, Yuki; Maruyama, Jun; Lee, Yong-soo; Kobayashi, Masaki; Nakagawa, Takashi; Minokoshi, Yasuhiko; Harada, Akihiro; Yamada, Masanobu; Kitamura, Tadahiro Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice DIABETOLOGIA, 57, 4, 819-831 DIABETOLOGIA, 57, 4, 819-831 DIABETOLOGIA, 57, 4, 819-831 2014 公開
Yoshino, Satoshi; Satoh, Tetsurou; Yamada, Masanobu; Hashimoto, Koshi; Tomaru, Takuya; Katano-Toki, Akiko; Kakizaki, Satoru; Okada, Shuichi; Shimizu, Hiroyuki; Ozawa, Atsushi; Tuchiya, Takafumi; Ikota, Hayato; Nakazato, Yoichi; Mori, Munemasa; Matozaki, Takashi; Sasaki, Tsutomu; Kitamura, Tadahiro; Mori, Masatomo Yoshino, Satoshi; Satoh, Tetsurou; Yamada, Masanobu; Hashimoto, Koshi; Tomaru, Takuya; Katano-Toki, Akiko; Kakizaki, Satoru; Okada, Shuichi; Shimizu, Hiroyuki; Ozawa, Atsushi; Tuchiya, Takafumi; Ikota, Hayato; Nakazato, Yoichi; Mori, Munemasa; Matozaki, Takashi; Sasaki, Tsutomu; Kitamura, Tadahiro; Mori, Masatomo Yoshino, Satoshi; Satoh, Tetsurou; Yamada, Masanobu; Hashimoto, Koshi; Tomaru, Takuya; Katano-Toki, Akiko; Kakizaki, Satoru; Okada, Shuichi; Shimizu, Hiroyuki; Ozawa, Atsushi; Tuchiya, Takafumi; Ikota, Hayato; Nakazato, Yoichi; Mori, Munemasa; Matozaki, Takashi; Sasaki, Tsutomu; Kitamura, Tadahiro; Mori, Masatomo Protection Against High-Fat Diet-Induced Obesity in Helz2-Deficient Male Mice Due to Enhanced Expression of Hepatic Leptin Receptor Protection Against High-Fat Diet-Induced Obesity in Helz2-Deficient Male Mice Due to Enhanced Expression of Hepatic Leptin Receptor Protection Against High-Fat Diet-Induced Obesity in Helz2-Deficient Male Mice Due to Enhanced Expression of Hepatic Leptin Receptor ENDOCRINOLOGY, 155, 9, 3459-3472 ENDOCRINOLOGY, 155, 9, 3459-3472 ENDOCRINOLOGY, 155, 9, 3459-3472 2014 公開
Susanti, Vina Yanti; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Matsui, Sho; Lee, Yong-Soo; Kikuchi, Osamu; Shimpuku, Mayumi; Kim, Hye-Jin; Kobayashi, Masaki; Kitamura, Tadahiro Susanti, Vina Yanti; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Matsui, Sho; Lee, Yong-Soo; Kikuchi, Osamu; Shimpuku, Mayumi; Kim, Hye-Jin; Kobayashi, Masaki; Kitamura, Tadahiro Susanti, Vina Yanti; Sasaki, Tsutomu; Yokota-Hashimoto, Hiromi; Matsui, Sho; Lee, Yong-Soo; Kikuchi, Osamu; Shimpuku, Mayumi; Kim, Hye-Jin; Kobayashi, Masaki; Kitamura, Tadahiro Sirt1 Rescues the Obesity Induced by Insulin-Resistant Constitutively-Nuclear FoxO1 in POMC Neurons of Male Mice Sirt1 Rescues the Obesity Induced by Insulin-Resistant Constitutively-Nuclear FoxO1 in POMC Neurons of Male Mice Sirt1 Rescues the Obesity Induced by Insulin-Resistant Constitutively-Nuclear FoxO1 in POMC Neurons of Male Mice OBESITY, 22, 10, 2115-2119 OBESITY, 22, 10, 2115-2119 OBESITY, 22, 10, 2115-2119 2014 公開
Masubuchi, Yosuke; Nakagawa, Yuko; Ma, Jinhui; Sasaki, Tsutomu; Kitamura, Tadahiro; Yamamoto, Yoritsuna; Kurose, Hitoshi; Kojima, Itaru; Shibata, Hiroshi Masubuchi, Yosuke; Nakagawa, Yuko; Ma, Jinhui; Sasaki, Tsutomu; Kitamura, Tadahiro; Yamamoto, Yoritsuna; Kurose, Hitoshi; Kojima, Itaru; Shibata, Hiroshi Masubuchi, Yosuke; Nakagawa, Yuko; Ma, Jinhui; Sasaki, Tsutomu; Kitamura, Tadahiro; Yamamoto, Yoritsuna; Kurose, Hitoshi; Kojima, Itaru; Shibata, Hiroshi A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells PLOS ONE, 8, 1, e54500 PLOS ONE, 8, 1, e54500 PLOS ONE, 8, 1, e54500 2013 公開
Lee, Y. -S.; Sasaki, T.; Kobayashi, M.; Kikuchi, O.; Kim, H. -J.; Yokota-Hashimoto, H.; Shimpuku, M.; Susanti, V. -Y.; Ido-Kitamura, Y.; Kimura, K.; Inoue, H.; Tanaka-Okamoto, M.; Ishizaki, H.; Miyoshi, J.; Ohya, S.; Tanaka, Y.; Kitajima, S.; Kitamura, T. Lee, Y. -S.; Sasaki, T.; Kobayashi, M.; Kikuchi, O.; Kim, H. -J.; Yokota-Hashimoto, H.; Shimpuku, M.; Susanti, V. -Y.; Ido-Kitamura, Y.; Kimura, K.; Inoue, H.; Tanaka-Okamoto, M.; Ishizaki, H.; Miyoshi, J.; Ohya, S.; Tanaka, Y.; Kitajima, S.; Kitamura, T. Lee, Y. -S.; Sasaki, T.; Kobayashi, M.; Kikuchi, O.; Kim, H. -J.; Yokota-Hashimoto, H.; Shimpuku, M.; Susanti, V. -Y.; Ido-Kitamura, Y.; Kimura, K.; Inoue, H.; Tanaka-Okamoto, M.; Ishizaki, H.; Miyoshi, J.; Ohya, S.; Tanaka, Y.; Kitajima, S.; Kitamura, T. Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice DIABETOLOGIA, 56, 6, 1383-1393 DIABETOLOGIA, 56, 6, 1383-1393 DIABETOLOGIA, 56, 6, 1383-1393 2013 公開
Syamsunarno, Mas Rizky A. A.; Iso, Tatsuya; Hanaoka, Hirofumi; Yamaguchi, Aiko; Obokata, Masaru; Koitabashi, Norimichi; Goto, Kosaku; Hishiki, Takako; Nagahata, Yoshiko; Matsui, Hiroki; Sano, Motoaki; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Maeda, Kazuhisa; Murakami, Masami; Kitamura, Tadahiro; Suematsu, Makoto; Tsushima, Yoshito; Endo, Keigo; Hotamisligil, Goekhan S.; Kurabayashi, Masahiko Syamsunarno, Mas Rizky A. A.; Iso, Tatsuya; Hanaoka, Hirofumi; Yamaguchi, Aiko; Obokata, Masaru; Koitabashi, Norimichi; Goto, Kosaku; Hishiki, Takako; Nagahata, Yoshiko; Matsui, Hiroki; Sano, Motoaki; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Maeda, Kazuhisa; Murakami, Masami; Kitamura, Tadahiro; Suematsu, Makoto; Tsushima, Yoshito; Endo, Keigo; Hotamisligil, Goekhan S.; Kurabayashi, Masahiko Syamsunarno, Mas Rizky A. A.; Iso, Tatsuya; Hanaoka, Hirofumi; Yamaguchi, Aiko; Obokata, Masaru; Koitabashi, Norimichi; Goto, Kosaku; Hishiki, Takako; Nagahata, Yoshiko; Matsui, Hiroki; Sano, Motoaki; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Maeda, Kazuhisa; Murakami, Masami; Kitamura, Tadahiro; Suematsu, Makoto; Tsushima, Yoshito; Endo, Keigo; Hotamisligil, Goekhan S.; Kurabayashi, Masahiko A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting PLOS ONE, 8, 11, e79386 PLOS ONE, 8, 11, e79386 PLOS ONE, 8, 11, e79386 2013 公開
Sasaki, Tsutomu; Shimpuku, Mayumi; Kitazumi, Tomoya; Hiraga, Haruna; Nakagawa, Yuko; Shibata, Hiroshi; Okamatsu-Ogura, Yuko; Kikuchi, Osamu; Kim, Hye-jin; Fujita, Yuki; Maruyama, Jun; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Saito, Masayuki; Kitamura, Tadahiro Sasaki, Tsutomu; Shimpuku, Mayumi; Kitazumi, Tomoya; Hiraga, Haruna; Nakagawa, Yuko; Shibata, Hiroshi; Okamatsu-Ogura, Yuko; Kikuchi, Osamu; Kim, Hye-jin; Fujita, Yuki; Maruyama, Jun; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Saito, Masayuki; Kitamura, Tadahiro Sasaki, Tsutomu; Shimpuku, Mayumi; Kitazumi, Tomoya; Hiraga, Haruna; Nakagawa, Yuko; Shibata, Hiroshi; Okamatsu-Ogura, Yuko; Kikuchi, Osamu; Kim, Hye-jin; Fujita, Yuki; Maruyama, Jun; Susanti, Vina Yanti; Yokota-Hashimoto, Hiromi; Kobayashi, Masaki; Saito, Masayuki; Kitamura, Tadahiro Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates ENDOCRINE JOURNAL, 60, 10, 1117-1129 ENDOCRINE JOURNAL, 60, 10, 1117-1129 ENDOCRINE JOURNAL, 60, 10, 1117-1129 2013 公開
Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K. Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K. Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K. Necdin controls foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. Necdin controls foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. Necdin controls foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. Journal of Neuroscience, 32, 16, 5562-72 Journal of Neuroscience, 32, 16, 5562-72 Journal of Neuroscience, 32, 16, 5562-72 2012 公開
Kikuchi O, Kobayashi M, Amano K, Sasaki T, Kitazumi T, Kim HJ, Lee YS, Yokota-Hashimoto H, Kitamura YI, Kitamura T Kikuchi O, Kobayashi M, Amano K, Sasaki T, Kitazumi T, Kim HJ, Lee YS, Yokota-Hashimoto H, Kitamura YI, Kitamura T Kikuchi O, Kobayashi M, Amano K, Sasaki T, Kitazumi T, Kim HJ, Lee YS, Yokota-Hashimoto H, Kitamura YI, Kitamura T FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization. FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization. FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization. PLoS One, 7, 2, e32249 PLoS One, 7, 2, e32249 PLoS One, 7, 2, e32249 2012 公開
Kobayashi M, Kikuchi O, Sasaki T, Kim HJ, Yokota-Hashimoto H, Lee YS, Amano K, Kitazumi T, Susanti VY, Kitamura YI, Kitamura T Kobayashi M, Kikuchi O, Sasaki T, Kim HJ, Yokota-Hashimoto H, Lee YS, Amano K, Kitazumi T, Susanti VY, Kitamura YI, Kitamura T Kobayashi M, Kikuchi O, Sasaki T, Kim HJ, Yokota-Hashimoto H, Lee YS, Amano K, Kitazumi T, Susanti VY, Kitamura YI, Kitamura T FoxO1 as a Double-edged Sword in the Pancreas: Analysis of Pancreas and β Cell-specific FoxO1 Knockout Mice. FoxO1 as a Double-edged Sword in the Pancreas: Analysis of Pancreas and β Cell-specific FoxO1 Knockout Mice. FoxO1 as a Double-edged Sword in the Pancreas: Analysis of Pancreas and β Cell-specific FoxO1 Knockout Mice. Am J Physiol Endocrinol Metab Am J Physiol Endocrinol Metab Am J Physiol Endocrinol Metab 2012 公開
Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T, Lee YS, Yokota-Hashimoto H, Susanti VY, Kitamura YI, Nakae J, Kitamura T Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T, Lee YS, Yokota-Hashimoto H, Susanti VY, Kitamura YI, Nakae J, Kitamura T Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T, Lee YS, Yokota-Hashimoto H, Susanti VY, Kitamura YI, Nakae J, Kitamura T Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance. Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance. Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance. Endocrinology Endocrinology Endocrinology 2012 公開
Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T. Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T. Ido-Kitamura Y, Sasaki T, Kobayashi M, Kim HJ, Lee YS, Kikuchi O, Yokota-Hashimoto H, Iizuka K, Accili D, Kitamura T. Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation. PLoS One, 7, 10, e47231 PLoS One, 7, 10, e47231 PLoS One, 7, 10, e47231 2012 公開
北村忠弘、佐々木努 北村忠弘、佐々木努 北村忠弘、佐々木努 POMC/CART（視床下部におけるFoxO1とSirt1） POMC/CART（視床下部におけるFoxO1とSirt1） POMC/CART（視床下部におけるFoxO1とSirt1） 生体の科学, 62, 1, 26-30 生体の科学, 62, 1, 26-30 生体の科学, 62, 1, 26-30 2011 公開
佐々木　努 北村　忠弘 佐々木　努 北村　忠弘 佐々木　努 北村　忠弘 Sirt1制御と食欲 Sirt1制御と食欲 Sirt1制御と食欲 メディカル・サイエンス・ダイジェスト, 37, 1, 16-19 メディカル・サイエンス・ダイジェスト, 37, 1, 16-19 メディカル・サイエンス・ダイジェスト, 37, 1, 16-19 2011 公開
Hirata M, Suzuki M, Ishii R, Satow R, Uchida T, Kitazumi T, Sasaki T, Kitamura T, Yamaguchi H, Nakamura Y, Fukami K. Hirata M, Suzuki M, Ishii R, Satow R, Uchida T, Kitazumi T, Sasaki T, Kitamura T, Yamaguchi H, Nakamura Y, Fukami K. Hirata M, Suzuki M, Ishii R, Satow R, Uchida T, Kitazumi T, Sasaki T, Kitamura T, Yamaguchi H, Nakamura Y, Fukami K. Genetic Defect in Phospholipase C{delta}1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis. Genetic Defect in Phospholipase C{delta}1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis. Genetic Defect in Phospholipase C{delta}1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis. Diabetes, 60, 7, 1926-37 Diabetes, 60, 7, 1926-37 Diabetes, 60, 7, 1926-37 2011 公開
Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T. Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T. Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T. Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Endocrinology, 151, 6, 2556-66 Endocrinology, 151, 6, 2556-66 Endocrinology, 151, 6, 2556-66 2010 公開
Sasaki T, Kitamura T. Sasaki T, Kitamura T. Sasaki T, Kitamura T. Roles of FoxO1 and Sirt1 in the central regulation of food intake. Roles of FoxO1 and Sirt1 in the central regulation of food intake. Roles of FoxO1 and Sirt1 in the central regulation of food intake. Endocrine Journal, 57, 11, 939-46 Endocrine Journal, 57, 11, 939-46 Endocrine Journal, 57, 11, 939-46 2010 公開
Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D. Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D. Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D. Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1. Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1. Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1. Molecular and Cellular Biology, Epub ahead of print Molecular and Cellular Biology, Epub ahead of print Molecular and Cellular Biology, Epub ahead of print 2009 公開
佐々木努、北村忠弘 佐々木努、北村忠弘 佐々木努、北村忠弘 「インスリンシグナルと老化」 「インスリンシグナルと老化」 「インスリンシグナルと老化」 内分泌・糖尿病科, 26, 601-606 内分泌・糖尿病科, 26, 601-606 内分泌・糖尿病科, 26, 601-606 2008 公開
Hankins GR, Sasaki T, Lieu AS, Saulle D, Karimi K, Li JZ, Helm GA. Hankins GR, Sasaki T, Lieu AS, Saulle D, Karimi K, Li JZ, Helm GA. Hankins GR, Sasaki T, Lieu AS, Saulle D, Karimi K, Li JZ, Helm GA. Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor. Neurosurgery, 63, 771-80 Neurosurgery, 63, 771-80 Neurosurgery, 63, 771-80 2008 公開
Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H. Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H. Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H. Phosphorylation regulates SIRT1 function. Phosphorylation regulates SIRT1 function. Phosphorylation regulates SIRT1 function. PLoS One, 3, e4020 PLoS One, 3, e4020 PLoS One, 3, e4020 2008 公開
Sasaki T, Maier B, Bartke A, Scrable H. Sasaki T, Maier B, Bartke A, Scrable H. Sasaki T, Maier B, Bartke A, Scrable H. Progressive loss of SIRT1 with cell cycle withdrawal. Progressive loss of SIRT1 with cell cycle withdrawal. Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell, 5, 413-422 Aging Cell, 5, 413-422 Aging Cell, 5, 413-422 2006 公開
Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. (Int J Biochem Cell Biol, 37: 913-919, 2005) Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. (Int J Biochem Cell Biol, 37: 913-919, 2005) Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. (Int J Biochem Cell Biol, 37: 913-919, 2005) DeltaNp53 or p44: priming the p53 pump. DeltaNp53 or p44: priming the p53 pump. DeltaNp53 or p44: priming the p53 pump. international journal of biochemistry & cell biology, 37, 913-919 international journal of biochemistry & cell biology, 37, 913-919 international journal of biochemistry & cell biology, 37, 913-919 2005 公開
Li JZ, Li H, Sasaki T, Holman D, Beres B, Dumont RJ, Pittman DD, Hankins GR, Helm GA. Li JZ, Li H, Sasaki T, Holman D, Beres B, Dumont RJ, Pittman DD, Hankins GR, Helm GA. Li JZ, Li H, Sasaki T, Holman D, Beres B, Dumont RJ, Pittman DD, Hankins GR, Helm GA. Osteogenic potential of five different recombinant human bone morphogenetic protein (BMP) vectors in rats. Osteogenic potential of five different recombinant human bone morphogenetic protein (BMP) vectors in rats. Osteogenic potential of five different recombinant human bone morphogenetic protein (BMP) vectors in rats. Gene Therapy, 10, 1735-1743 Gene Therapy, 10, 1735-1743 Gene Therapy, 10, 1735-1743 2003 公開
Sasaki T, Hankins GR, Helm GA. Sasaki T, Hankins GR, Helm GA. Sasaki T, Hankins GR, Helm GA. Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip. Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip. Comparison of gene expression profiles between frozen original meningiomas and primary cultures of the meningiomas by GeneChip. Neurosurgery, 52, 892-899 Neurosurgery, 52, 892-899 Neurosurgery, 52, 892-899 2003 公開
Sasaki T, Lopes MBS, Hankins GR, Helm GA. Sasaki T, Lopes MBS, Hankins GR, Helm GA. Sasaki T, Lopes MBS, Hankins GR, Helm GA. Expression of survivin, inhibitor of apoptosis protein, in tumors of the nervous system. Expression of survivin, inhibitor of apoptosis protein, in tumors of the nervous system. Expression of survivin, inhibitor of apoptosis protein, in tumors of the nervous system. Acta Neuropathologica (Berlin), 104, 105-109 Acta Neuropathologica (Berlin), 104, 105-109 Acta Neuropathologica (Berlin), 104, 105-109 2002 公開
Jane JA Jr, Dunford BA, Kron A, Pittman DD, Sasaki T, Li JZ, Li H, Alden TD, Dayoub H, Hankins GR, Kallmes DF, Helm GA. Jane JA Jr, Dunford BA, Kron A, Pittman DD, Sasaki T, Li JZ, Li H, Alden TD, Dayoub H, Hankins GR, Kallmes DF, Helm GA. Jane JA Jr, Dunford BA, Kron A, Pittman DD, Sasaki T, Li JZ, Li H, Alden TD, Dayoub H, Hankins GR, Kallmes DF, Helm GA. Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer. Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer. Ectopic Osteogenesis Using Adenoviral Bone Morphogenetic Protein (BMP)-4 and BMP-6 Gene Transfer. Molecular Therapy, 6, 464-470 Molecular Therapy, 6, 464-470 Molecular Therapy, 6, 464-470 2002 公開
Sasaki T, Hankins GR, Helm GA. Sasaki T, Hankins GR, Helm GA. Sasaki T, Hankins GR, Helm GA. Major Vault Protein/Lung resistance-related protein (MVP/LRP) expression in nervous system tumors. Major Vault Protein/Lung resistance-related protein (MVP/LRP) expression in nervous system tumors. Major Vault Protein/Lung resistance-related protein (MVP/LRP) expression in nervous system tumors. Brain Tumor Pathology, 19, 59-62 Brain Tumor Pathology, 19, 59-62 Brain Tumor Pathology, 19, 59-62 2002 公開
Sasaki T, Sasaki T, Okamoto K, Ishida T, Kirino T. Sasaki T, Sasaki T, Okamoto K, Ishida T, Kirino T. Sasaki T, Sasaki T, Okamoto K, Ishida T, Kirino T. Cavernous angioma of the internal acoustic meatus--case report. Cavernous angioma of the internal acoustic meatus--case report. Cavernous angioma of the internal acoustic meatus--case report. Neurologia-medico chirurgica (Tokyo), 39, 847-851 Neurologia-medico chirurgica (Tokyo), 39, 847-851 Neurologia-medico chirurgica (Tokyo), 39, 847-851 1999 公開
ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. 有 公開
Expression of survivin, an inhibitor of apoptosis protein, in tumors of the nervous system. Expression of survivin, an inhibitor of apoptosis protein, in tumors of the nervous system. Expression of survivin, an inhibitor of apoptosis protein, in tumors of the nervous system. 有 公開
Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis. Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis. Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis. 有 公開
Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. 有 公開
Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression 有 公開

  • <<
  • >>
  • 表示
タイトル言語:
書籍等出版物
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 出版社 出版社(日本語) 出版社(英語) 出版年月 記述言語 担当区分 公開
佐々木　努 佐々木　努 佐々木　努 New Diet Therapy New Diet Therapy New Diet Therapy 2019/06 公開
佐々木　努 佐々木　努 佐々木　努 Bioscience & Industry Bioscience & Industry Bioscience & Industry 2019/05 公開
佐々木　努 佐々木　努 佐々木　努 糖尿病学2019 糖尿病学2019 糖尿病学2019 2019/05 公開
佐々木　努 佐々木　努 佐々木　努 栄養と料理、2019年５月号 栄養と料理、2019年５月号 栄養と料理、2019年５月号 2019/04 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2019年5月号 実験医学2019年5月号 実験医学2019年5月号 2019/04 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2019年1月号 実験医学2019年1月号 実験医学2019年1月号 羊土社 羊土社 羊土社 2018/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2018年7月号 実験医学2018年7月号 実験医学2018年7月号 羊土社 羊土社 羊土社 2018/06 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2018年1月号 実験医学2018年1月号 実験医学2018年1月号 羊土社 羊土社 羊土社 2017/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2017年7月号 実験医学2017年7月号 実験医学2017年7月号 羊土社 羊土社 羊土社 2017/06 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2017年4月号 実験医学2017年4月号 実験医学2017年4月号 羊土社 羊土社 羊土社 2017/03 公開
佐々木　努 佐々木　努 佐々木　努 月間糖尿病2017年3月号 月間糖尿病2017年3月号 月間糖尿病2017年3月号 医学出版 医学出版 医学出版 2017 公開
佐々木　努 佐々木　努 佐々木　努 肥満と疾患　どこまで解明されたか？ 肥満と疾患　どこまで解明されたか？ 肥満と疾患　どこまで解明されたか？ 上毛新聞社 上毛新聞社 上毛新聞社 2017 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2017年１月号 実験医学2017年１月号 実験医学2017年１月号 羊土社 羊土社 羊土社 2016/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2016年６月号 実験医学2016年６月号 実験医学2016年６月号 羊土社 羊土社 羊土社 2016/05 公開
佐々木努、北村忠弘 佐々木努、北村忠弘 佐々木努、北村忠弘 実験医学別冊「マウス表現型解析スタンダード」 実験医学別冊「マウス表現型解析スタンダード」 実験医学別冊「マウス表現型解析スタンダード」 羊土社 羊土社 羊土社 2016 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2016年１月号 実験医学2016年１月号 実験医学2016年１月号 羊土社 羊土社 羊土社 2015/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2015年7月号 実験医学2015年7月号 実験医学2015年7月号 羊土社 羊土社 羊土社 2015/06 公開
佐々木　努 佐々木　努 佐々木　努 精神神経学雑誌 精神神経学雑誌 精神神経学雑誌 2015 公開
佐々木　努 佐々木　努 佐々木　努 内分泌・糖尿病・代謝内科 内分泌・糖尿病・代謝内科 内分泌・糖尿病・代謝内科 2015 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2015年１月号 実験医学2015年１月号 実験医学2015年１月号 羊土社 羊土社 羊土社 2014/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2014年７月号 実験医学2014年７月号 実験医学2014年７月号 羊土社 羊土社 羊土社 2014/06 公開
佐々木　努 佐々木　努 佐々木　努 実験医学１月号(2014) 実験医学１月号(2014) 実験医学１月号(2014) 羊土社 羊土社 羊土社 2013/12 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2013年10月号 実験医学2013年10月号 実験医学2013年10月号 羊土社 羊土社 羊土社 2013/09 公開
佐々木　努 佐々木　努 佐々木　努 レスベラトロールの基礎と応用 レスベラトロールの基礎と応用 レスベラトロールの基礎と応用 シーエムシー出版 シーエムシー出版 シーエムシー出版 2012 公開
北村　忠弘、佐々木　努 北村　忠弘、佐々木　努 北村　忠弘、佐々木　努 生体の科学 生体の科学 生体の科学 2011 公開
佐々木　努、北村　忠弘 佐々木　努、北村　忠弘 佐々木　努、北村　忠弘 Medical Science Digest Medical Science Digest Medical Science Digest 2011 公開
佐々木　努、北村　忠弘 佐々木　努、北村　忠弘 佐々木　努、北村　忠弘 内分泌・糖尿病科 内分泌・糖尿病科 内分泌・糖尿病科 2008 公開
佐々木　努 佐々木　努 佐々木　努 実験医学2004年11月号 実験医学2004年11月号 実験医学2004年11月号 2004/10 公開

  • <<
  • >>
  • 表示
タイトル言語:
学術賞等
賞の名称(日本語) 賞の名称(英語) 授与組織名(日本語) 授与組織名(英語) 年月
日本内分泌学会YIA Japan Endocrine Society Young Investigator Award 日本内分泌学会 Japan Endocrine Society 2013/04/26
自ら企画した研究集会
集会名 学会名 年月
生理学研究所研究会「食欲・食嗜好の分子神経基盤」 2016
生理学研究所研究会「食欲・食嗜好の分子神経基盤」 2017
生理学研究所研究会「食欲・食嗜好の分子神経基盤」 2018
食の「満足感」を担う分子・神経基盤研究会（食欲・食嗜好研究会） 2019/08/26
外部資金：競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
科研費基盤B (17H01971) 代表 神経系による食嗜好の制御メカニズムの解明；長寿遺伝子SIRT1に着眼して 2017/04/01〜2021/03/31
新学術公募（意志動力学） (17H06050) 代表 社会環境と体内環境の情報を統合する脳のSIRT1の意志力における役割の解明 2017/04/01〜2019/03/31
挑戦的研究（萌芽） (18K19726) 代表 長寿遺伝子SIRT1によるアルコール嗜好性の制御メカニズムの解明とその応用 2018/07/01〜2020/03/31
科研費基盤C (25460310) 代表 視床下部Sirt1とFoxO1による全身エネルギーバランス制御機序の解析 2013/04/01〜2016/03/31
新学術領域「転写代謝システム」公募班 (24116505) 代表 代謝シグナルによる視床下部NAD依存性脱アセチル化酵素SIRT1の制御機構の解明 2012/04/01〜2014/03/31
科研費若手B (23790270) 代表 視床下部Sirt1によるエネルギーバランス制御の分子機構の解明 2011/04/01〜2013/03/31
科研費若手B (20790637) 代表 視床下部におけるSIRT１のエネルギー代謝制御機構の解明 2008/04/01〜2010/03/31
外部資金：競争的資金・科学研究費補助金以外
制度名 代表者名 研究課題(日本語) 研究課題(英語) 期間
京都発革新的医療技術研究開発助成事業 佐々木　努 飲酒欲求の抑制法の開発 2019〜
三島海雲記念財団 佐々木　努 食嗜好を制御する神経ネットワークの解明 2019〜
日本うま味調味料協会　技術部会 佐々木　努 たんぱく質嗜好性の制御メカニズムの解明 2019〜
日本応用酵素協会　酵素研究助成 佐々木　努 SIRT1による栄養素嗜好性の制御機序の解明 2019〜
不二たん白質研究振興財団 佐々木　努 たん白質嗜好性の制御メカニズムの解明 2019〜
担当科目
講義名(日本語) 講義名(英語) 開講期 学部/研究科 年度
栄養化学 Nutrition Chemistry 後期 農学部 2019/04〜2020/03
栄養化学専攻実験１ Experimental Course in Nutrition Chemistry1 通年 農学研究科 2019/04〜2020/03
栄養化学専攻実験２ Experimental Course in Nutrition Chemistry2 通年 農学研究科 2019/04〜2020/03
栄養化学専攻演習１ Nutrition Chemistry Seminar1 通年 農学研究科 2019/04〜2020/03
栄養化学専攻演習２ Nutrition Chemistry Seminar2 通年 農学研究科 2019/04〜2020/03
栄養生理学実験及び実験法 Laboratory course in Nutrition Physiology 後期 農学部 2019/04〜2020/03
栄養生理学特論 I Advanced Course of Nuturitional Physiology I 後期集中 農学研究科 2019/04〜2020/03
栄養・食品科学演習 Seminar on Nutrition and Food Science 後期 農学部 2019/04〜2020/03
部局運営（役職等）
役職名 期間
国際交流委員会　委員 2019/04/01〜2021/03/31
その他活動：その他
活動名 内容 期間
群馬県立高崎高等学校SSH運営指導委員 スーパーサイエンスハイスクール(SSH)の指導助言 2016/04/01〜

前のページへ戻る

このページのTOPへ