山口 建

最終更新日時: 2019/06/07 13:59:16

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氏名(漢字/フリガナ/アルファベット表記)
山口 建/ヤマグチ ケン/Yamaguchi, Ken
所属部署・職名(部局/所属/講座等/職名)
医学研究科/医学専攻器官外科学講座婦人科学・産科学/講師
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 京都大学
ORCID ID
https://orcid.org/0000-0002-7669-1405
researchmap URL
https://researchmap.jp/7000009446
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
M. Koshiyama; N. Matsumura; T. Baba; K. Yamaguchi; Y. Yoshioka; I. Konishi M. Koshiyama; N. Matsumura; T. Baba; K. Yamaguchi; Y. Yoshioka; I. Konishi M. Koshiyama; N. Matsumura; T. Baba; K. Yamaguchi; Y. Yoshioka; I. Konishi Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib Cancer Biology and Therapy, 15, 1, 22-25 Cancer Biology and Therapy, 15, 1, 22-25 Cancer Biology and Therapy, 15, 1, 22-25 2014 英語 公開
K. Yamaguchi; Z. Huang; N. Matsumura; M. Mandai; T. Okamoto; T. Baba; I. Konishi; A. Berchuck; S.K. Murphy K. Yamaguchi; Z. Huang; N. Matsumura; M. Mandai; T. Okamoto; T. Baba; I. Konishi; A. Berchuck; S.K. Murphy K. Yamaguchi; Z. Huang; N. Matsumura; M. Mandai; T. Okamoto; T. Baba; I. Konishi; A. Berchuck; S.K. Murphy Epigenetic determinants of ovarian clear cell carcinoma biology Epigenetic determinants of ovarian clear cell carcinoma biology Epigenetic determinants of ovarian clear cell carcinoma biology International Journal of Cancer International Journal of Cancer International Journal of Cancer 2014 英語 公開
K. Abiko; M. Mandai; J. Hamanishi; Y. Yoshioka; N. Matsumura; T. Baba; K. Yamaguchi; R. Murakami; A. Yamamoto; B. Kharma; K. Kosaka; I. Konishi K. Abiko; M. Mandai; J. Hamanishi; Y. Yoshioka; N. Matsumura; T. Baba; K. Yamaguchi; R. Murakami; A. Yamamoto; B. Kharma; K. Kosaka; I. Konishi K. Abiko; M. Mandai; J. Hamanishi; Y. Yoshioka; N. Matsumura; T. Baba; K. Yamaguchi; R. Murakami; A. Yamamoto; B. Kharma; K. Kosaka; I. Konishi PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction Clinical Cancer Research, 19, 6, 1363-1374 Clinical Cancer Research, 19, 6, 1363-1374 Clinical Cancer Research, 19, 6, 1363-1374 2013/03/15 英語 公開
B. Kharma; T. Baba; M. Mandai; N. Matsumura; S.K. Murphy; H.S. Kang; K. Yamanoi; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; I. Konishi B. Kharma; T. Baba; M. Mandai; N. Matsumura; S.K. Murphy; H.S. Kang; K. Yamanoi; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; I. Konishi B. Kharma; T. Baba; M. Mandai; N. Matsumura; S.K. Murphy; H.S. Kang; K. Yamanoi; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; I. Konishi Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers International Journal of Cancer, 133, 9, 2234-2244 International Journal of Cancer, 133, 9, 2234-2244 International Journal of Cancer, 133, 9, 2234-2244 2013 英語 公開
A. Nishikawa; E. Kondoh; J. Hamanishi; K. Yamaguchi; A. Ueda; Y. Sato; I. Konishi A. Nishikawa; E. Kondoh; J. Hamanishi; K. Yamaguchi; A. Ueda; Y. Sato; I. Konishi A. Nishikawa; E. Kondoh; J. Hamanishi; K. Yamaguchi; A. Ueda; Y. Sato; I. Konishi Ileal perforation and massive intestinal haemorrhage from endometriosis in pregnancy: Case report and literature review Ileal perforation and massive intestinal haemorrhage from endometriosis in pregnancy: Case report and literature review Ileal perforation and massive intestinal haemorrhage from endometriosis in pregnancy: Case report and literature review European Journal of Obstetrics Gynecology and Reproductive Biology, 170, 1, 20-24 European Journal of Obstetrics Gynecology and Reproductive Biology, 170, 1, 20-24 European Journal of Obstetrics Gynecology and Reproductive Biology, 170, 1, 20-24 2013 英語 公開
T. Okamoto; M. Mandai; N. Matsumura; K. Yamaguchi; H. Kondoh; Y. Amano; T. Baba; J. Hamanishi; K. Abiko; K. Kosaka; S.K. Murphy; S. Mori; I. Konishi T. Okamoto; M. Mandai; N. Matsumura; K. Yamaguchi; H. Kondoh; Y. Amano; T. Baba; J. Hamanishi; K. Abiko; K. Kosaka; S.K. Murphy; S. Mori; I. Konishi T. Okamoto; M. Mandai; N. Matsumura; K. Yamaguchi; H. Kondoh; Y. Amano; T. Baba; J. Hamanishi; K. Abiko; K. Kosaka; S.K. Murphy; S. Mori; I. Konishi Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma Molecular Carcinogenesis Molecular Carcinogenesis Molecular Carcinogenesis 2013 英語 公開
K. Yamanoi; N. Matsumura; A. Kido; T. Baba; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; H.A. Taleb; K. Togashi; I. Konishi K. Yamanoi; N. Matsumura; A. Kido; T. Baba; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; H.A. Taleb; K. Togashi; I. Konishi K. Yamanoi; N. Matsumura; A. Kido; T. Baba; J. Hamanishi; K. Yamaguchi; Y. Yoshioka; H.A. Taleb; K. Togashi; I. Konishi A novel diagnostic criterion for lymph node metastasis in cervical cancer using multi-detector computed tomography A novel diagnostic criterion for lymph node metastasis in cervical cancer using multi-detector computed tomography A novel diagnostic criterion for lymph node metastasis in cervical cancer using multi-detector computed tomography Gynecologic Oncology, 131, 3, 701-707 Gynecologic Oncology, 131, 3, 701-707 Gynecologic Oncology, 131, 3, 701-707 2013 英語 公開
S. Yamamura; N. Matsumura; M. Mandai; Z. Huang; T. Oura; T. Baba; J. Hamanishi; K. Yamaguchi; H.S. Kang; T. Okamoto; K. Abiko; S. Mori; S.K. Murphy; I. Konishi S. Yamamura; N. Matsumura; M. Mandai; Z. Huang; T. Oura; T. Baba; J. Hamanishi; K. Yamaguchi; H.S. Kang; T. Okamoto; K. Abiko; S. Mori; S.K. Murphy; I. Konishi S. Yamamura; N. Matsumura; M. Mandai; Z. Huang; T. Oura; T. Baba; J. Hamanishi; K. Yamaguchi; H.S. Kang; T. Okamoto; K. Abiko; S. Mori; S.K. Murphy; I. Konishi The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer International Journal of Cancer, 130, 1, 20-28 International Journal of Cancer, 130, 1, 20-28 International Journal of Cancer, 130, 1, 20-28 2012 英語 公開
M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; J. Hamanishi; I. Konishi M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; J. Hamanishi; I. Konishi M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; J. Hamanishi; I. Konishi Ovarian clear cell carcinoma as a stress-responsive cancer: Influence of the microenvironment on the carcinogenesis and cancer phenotype Ovarian clear cell carcinoma as a stress-responsive cancer: Influence of the microenvironment on the carcinogenesis and cancer phenotype Ovarian clear cell carcinoma as a stress-responsive cancer: Influence of the microenvironment on the carcinogenesis and cancer phenotype Cancer Letters, 310, 2, 129-133 Cancer Letters, 310, 2, 129-133 Cancer Letters, 310, 2, 129-133 2011 英語 公開
E. Kondoh; S. Mori; K. Yamaguchi; T. Baba; N. Matsumura; J.C. Barnett; R.S. Whitaker; I. Konishi; S. Fujii; A. Berchuck; S.K. Murphy E. Kondoh; S. Mori; K. Yamaguchi; T. Baba; N. Matsumura; J.C. Barnett; R.S. Whitaker; I. Konishi; S. Fujii; A. Berchuck; S.K. Murphy E. Kondoh; S. Mori; K. Yamaguchi; T. Baba; N. Matsumura; J.C. Barnett; R.S. Whitaker; I. Konishi; S. Fujii; A. Berchuck; S.K. Murphy Targeting slow-proliferating ovarian cancer cells Targeting slow-proliferating ovarian cancer cells Targeting slow-proliferating ovarian cancer cells International Journal of Cancer, 126, 10, 2448-2456 International Journal of Cancer, 126, 10, 2448-2456 International Journal of Cancer, 126, 10, 2448-2456 2010/05/15 英語 公開
K. Yamaguchi; M. Mandai; T. Oura; N. Matsumura; J. Hamanishi; T. Baba; S. Matsui; S.K. Murphy; I. Konishi K. Yamaguchi; M. Mandai; T. Oura; N. Matsumura; J. Hamanishi; T. Baba; S. Matsui; S.K. Murphy; I. Konishi K. Yamaguchi; M. Mandai; T. Oura; N. Matsumura; J. Hamanishi; T. Baba; S. Matsui; S.K. Murphy; I. Konishi Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes Oncogene, 29, 12, 1741-1752 Oncogene, 29, 12, 1741-1752 Oncogene, 29, 12, 1741-1752 2010/03 英語 公開
J. Hamanishi; M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; S. Fujii; I. Konishi J. Hamanishi; M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; S. Fujii; I. Konishi J. Hamanishi; M. Mandai; N. Matsumura; T. Baba; K. Yamaguchi; S. Fujii; I. Konishi Activated local immunity by CC chemokine ligand 19-transduced embryonic endothelial progenitor cells suppresses metastasis of murine ovarian cancer Activated local immunity by CC chemokine ligand 19-transduced embryonic endothelial progenitor cells suppresses metastasis of murine ovarian cancer Activated local immunity by CC chemokine ligand 19-transduced embryonic endothelial progenitor cells suppresses metastasis of murine ovarian cancer Stem Cells, 28, 1, 164-173 Stem Cells, 28, 1, 164-173 Stem Cells, 28, 1, 164-173 2010/01 英語 公開
N. Matsumura; M. Mandai; T. Okamoto; K. Yamaguchi; S. Yamamura; T. Oura; T. Baba; J. Hamanishi; H.S. Kang; S. Matsui; S. Mori; S.K. Murphy; I. Konishi N. Matsumura; M. Mandai; T. Okamoto; K. Yamaguchi; S. Yamamura; T. Oura; T. Baba; J. Hamanishi; H.S. Kang; S. Matsui; S. Mori; S.K. Murphy; I. Konishi N. Matsumura; M. Mandai; T. Okamoto; K. Yamaguchi; S. Yamamura; T. Oura; T. Baba; J. Hamanishi; H.S. Kang; S. Matsui; S. Mori; S.K. Murphy; I. Konishi Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling Cancer Science, 101, 12, 2658-2663 Cancer Science, 101, 12, 2658-2663 Cancer Science, 101, 12, 2658-2663 2010 英語 公開
M. Mandai; K. Yamaguchi; N. Matsumura; T. Baba; I. Konishi M. Mandai; K. Yamaguchi; N. Matsumura; T. Baba; I. Konishi M. Mandai; K. Yamaguchi; N. Matsumura; T. Baba; I. Konishi Ovarian cancer in endometriosis: Molecular biology, pathology, and clinical management Ovarian cancer in endometriosis: Molecular biology, pathology, and clinical management Ovarian cancer in endometriosis: Molecular biology, pathology, and clinical management International Journal of Clinical Oncology, 14, 5, 383-391 International Journal of Clinical Oncology, 14, 5, 383-391 International Journal of Clinical Oncology, 14, 5, 383-391 2009/10 英語 公開
K. Li; M. Mandai; J. Hamanishi; N. Matsumura; A. Suzuki; H. Yagi; K. Yamaguchi; T. Baba; S. Fujii; I. Konishi K. Li; M. Mandai; J. Hamanishi; N. Matsumura; A. Suzuki; H. Yagi; K. Yamaguchi; T. Baba; S. Fujii; I. Konishi K. Li; M. Mandai; J. Hamanishi; N. Matsumura; A. Suzuki; H. Yagi; K. Yamaguchi; T. Baba; S. Fujii; I. Konishi Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: High expression of ULBP2 is an indicator of poor prognosis Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: High expression of ULBP2 is an indicator of poor prognosis Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: High expression of ULBP2 is an indicator of poor prognosis Cancer Immunology, Immunotherapy, 58, 5, 641-652 Cancer Immunology, Immunotherapy, 58, 5, 641-652 Cancer Immunology, Immunotherapy, 58, 5, 641-652 2009 英語 公開
K. Yamaguchi; M. Mandai; S. Toyokuni; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii K. Yamaguchi; M. Mandai; S. Toyokuni; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii K. Yamaguchi; M. Mandai; S. Toyokuni; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent oxidative stress Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent oxidative stress Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent oxidative stress Clinical Cancer Research, 14, 1, 32-40 Clinical Cancer Research, 14, 1, 32-40 Clinical Cancer Research, 14, 1, 32-40 2008 英語 公開
N. Matsumura; M. Mandai; J. Hamanishi; K. Yamaguchi; K. Fukuhara; H. Yagi; T. Higuchi; K. Takakura; S. Fujii N. Matsumura; M. Mandai; J. Hamanishi; K. Yamaguchi; K. Fukuhara; H. Yagi; T. Higuchi; K. Takakura; S. Fujii N. Matsumura; M. Mandai; J. Hamanishi; K. Yamaguchi; K. Fukuhara; H. Yagi; T. Higuchi; K. Takakura; S. Fujii Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: Utilization for ovarian cancer treatment Oncology Reports, 19, 2, 505-515 Oncology Reports, 19, 2, 505-515 Oncology Reports, 19, 2, 505-515 2008 英語 公開
K. Yamaguchi; M. Mandai; K. Fukuhara; T. Higuchi; J. Hamanishi; K. Takakura; S. Fujii K. Yamaguchi; M. Mandai; K. Fukuhara; T. Higuchi; J. Hamanishi; K. Takakura; S. Fujii K. Yamaguchi; M. Mandai; K. Fukuhara; T. Higuchi; J. Hamanishi; K. Takakura; S. Fujii Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period Oncology Reports, 19, 3, 705-711 Oncology Reports, 19, 3, 705-711 Oncology Reports, 19, 3, 705-711 2008 英語 公開
M. Miyanishi; M. Mandai; N. Matsumura; K. Yamaguchi; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii M. Miyanishi; M. Mandai; N. Matsumura; K. Yamaguchi; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii M. Miyanishi; M. Mandai; N. Matsumura; K. Yamaguchi; J. Hamanishi; T. Higuchi; K. Takakura; S. Fujii Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression Oncology Reports, 17, 2, 329-333 Oncology Reports, 17, 2, 329-333 Oncology Reports, 17, 2, 329-333 2007 英語 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
J. Hamanishi; M. Mandai; M. Iwasaki; T. Okazaki; Y. Tanaka; K. Yamaguchi; T. Higuchi; H. Yagi; K. Takakura; N. Minato; T. Honjo; S. Fujii J. Hamanishi; M. Mandai; M. Iwasaki; T. Okazaki; Y. Tanaka; K. Yamaguchi; T. Higuchi; H. Yagi; K. Takakura; N. Minato; T. Honjo; S. Fujii J. Hamanishi; M. Mandai; M. Iwasaki; T. Okazaki; Y. Tanaka; K. Yamaguchi; T. Higuchi; H. Yagi; K. Takakura; N. Minato; T. Honjo; S. Fujii Programmed cell death 1 ligand 1 and tumor-infiltrating CD8<sup>+</sup> T lymphocytes are prognostic factors of human ovarian cancer Programmed cell death 1 ligand 1 and tumor-infiltrating CD8<sup>+</sup> T lymphocytes are prognostic factors of human ovarian cancer Programmed cell death 1 ligand 1 and tumor-infiltrating CD8<sup>+</sup> T lymphocytes are prognostic factors of human ovarian cancer Proceedings of the National Academy of Sciences of the United States of America, 104, 9, 3360-3365 Proceedings of the National Academy of Sciences of the United States of America, 104, 9, 3360-3365 Proceedings of the National Academy of Sciences of the United States of America, 104, 9, 3360-3365 2007 英語 公開
タイトル言語:
外部資金:競争的資金 (科学研究費補助金)
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
若手研究(B) 代表 卵巣明細胞腺癌におけるメタボローム解析とオートファジーの役割 2012〜2013
若手研究(B) 代表 卵巣がん関連遺伝子の網羅的メタボローム解析 (平成26年度分) 2014/04/01〜2015/03/31
若手研究(B) 代表 卵巣がん関連遺伝子の網羅的メタボローム解析 (平成27年度分) 2015/04/01〜2016/03/31
基盤研究(C) 代表 リキッドバイオプシーを用いた卵巣癌の術前組織診断法と卵巣癌予測診断法の開発 (平成30年度分) 2018/04/01〜2019/03/31