中川 正宏

最終更新日時: 2019/06/19 23:23:03

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氏名(漢字/フリガナ/アルファベット表記)
中川 正宏/ナカガワ マサヒロ/Nakagawa, Masahiro
所属部署・職名(部局/所属/講座等/職名)
医学研究科/メディカルイノベーションセンター/特定講師
取得学位
学位名(日本語) 学位名(英語) 大学(日本語) 大学(英語) 取得区分
博士(医学) 東京大学
ORCID ID
https://orcid.org/0000-0002-6420-2555
researchmap URL
https://researchmap.jp/7000017224
研究テーマ
(日本語)
造血器腫瘍の単一細胞解析
(英語)
Single cell analysis of hematological malignancies.
研究概要
(日本語)
新規の単一細胞解析手法の構築とそれを用いた造血器腫瘍のクローン解析
(英語)
Development of novel single cell analysis platform and clonal analysis of hematological malignancies.
研究分野(キーワード)
キーワード(日本語) キーワード(英語)
造血器腫瘍 hematological malignancies
単一細胞解析 single cell analysis
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Watatani Y, Sato Y, Miyoshi H, Sakamoto K, Nishida K, Gion Y, Nagata Y, Shiraishi Y, Chiba K, Tanaka H, Zhao L, Ochi Y, Takeuchi Y, Takeda J, Ueno H, Kataoka K Watatani Y, Sato Y, Miyoshi H, Sakamoto K, Nishida K, Gion Y, Nagata Y, Shiraishi Y, Chiba K, Tanaka H, Zhao L, Ochi Y, Takeuchi Y, Takeda J, Ueno H, Kataoka K Watatani Y, Sato Y, Miyoshi H, Sakamoto K, Nishida K, Gion Y, Nagata Y, Shiraishi Y, Chiba K, Tanaka H, Zhao L, Ochi Y, Takeuchi Y, Takeda J, Ueno H, Kataoka K Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling. Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling. Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling. Leukemia Leukemia Leukemia 2019/05 公開
Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y, Shiozawa Y, Sato Y, Aoki K, Kim SK, Fujii Y, Yoshida K, Kataoka K, Nakagawa MM, Ogawa S Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y, Shiozawa Y, Sato Y, Aoki K, Kim SK, Fujii Y, Yoshida K, Kataoka K, Nakagawa MM, Ogawa S Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y, Shiozawa Y, Sato Y, Aoki K, Kim SK, Fujii Y, Yoshida K, Kataoka K, Nakagawa MM, Ogawa S Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature Nature Nature 2019/01 公開
Masahiro Marshall Nakagawa, Chozha Vendan Rathinam Masahiro Marshall Nakagawa, Chozha Vendan Rathinam Masahiro Marshall Nakagawa, Chozha Vendan Rathinam Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells Cell Reports, 25, 8, 2094 Cell Reports, 25, 8, 2094 Cell Reports, 25, 8, 2094 2018/11 公開
Masahiro Marshall Nakagawa, Harry Davis, Chozha Vendan Rathinam Masahiro Marshall Nakagawa, Harry Davis, Chozha Vendan Rathinam Masahiro Marshall Nakagawa, Harry Davis, Chozha Vendan Rathinam A20 deficiency in multipotent progenitors perturbs quiescence of hematopoietic stem cells A20 deficiency in multipotent progenitors perturbs quiescence of hematopoietic stem cells A20 deficiency in multipotent progenitors perturbs quiescence of hematopoietic stem cells Stem Cell Research Stem Cell Research Stem Cell Research 2018/10 公開
Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa PhysiologicalSrsf2P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice PhysiologicalSrsf2P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice PhysiologicalSrsf2P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice Blood, 131, 6, blood-635 Blood, 131, 6, blood-635 Blood, 131, 6, blood-635 2018/02 公開
Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway H.E, Sekeres M.A, Radivoyevitch T, Yoshida K, Sanada M, Yoshizato T, Kataoka K, Nakagawa M.M, Ueno H, Nannya Y, Kon A, Shiozawa Y, Takeda J, Shiraishi Y, Chiba K, Miyano S, Singh J, Padgett R.A, Ogawa S, Maciejewski J.P, Makishima H. Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway H.E, Sekeres M.A, Radivoyevitch T, Yoshida K, Sanada M, Yoshizato T, Kataoka K, Nakagawa M.M, Ueno H, Nannya Y, Kon A, Shiozawa Y, Takeda J, Shiraishi Y, Chiba K, Miyano S, Singh J, Padgett R.A, Ogawa S, Maciejewski J.P, Makishima H. Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway H.E, Sekeres M.A, Radivoyevitch T, Yoshida K, Sanada M, Yoshizato T, Kataoka K, Nakagawa M.M, Ueno H, Nannya Y, Kon A, Shiozawa Y, Takeda J, Shiraishi Y, Chiba K, Miyano S, Singh J, Padgett R.A, Ogawa S, Maciejewski J.P, Makishima H. A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia Leukemia, 32, 3, 839-843 Leukemia, 32, 3, 839-843 Leukemia, 32, 3, 839-843 2018 公開
Nakagawa M.M, Chen H, Rathinam C.V. Nakagawa M.M, Chen H, Rathinam C.V. Nakagawa M.M, Chen H, Rathinam C.V. Constitutive activation of NF-κB pathway in hematopoietic stem cells causes loss of quiescence and deregulated transcription factor networks Constitutive activation of NF-κB pathway in hematopoietic stem cells causes loss of quiescence and deregulated transcription factor networks Constitutive activation of NF-κB pathway in hematopoietic stem cells causes loss of quiescence and deregulated transcription factor networks Frontiers in Cell and Developmental Biology, 6, OCT Frontiers in Cell and Developmental Biology, 6, OCT Frontiers in Cell and Developmental Biology, 6, OCT 2018 公開
Yoshizato T, Nannya Y, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Suzuki H, Nagata Y, Sato Y, Kakiuchi N, Matsuo K, Onizuka M, Kataoka K, Chiba K, Tanaka H, Ueno H, Nakagawa M.M, Przychodzen B, Haferlach C, Kern W, Aoki K, Itonaga H, Kanda Y, Sekeres M.A, Maciejewski J.P, Haferlach T, Miyazaki Y, Horibe K, Sanada M, Miyano S, Makishima H, Ogawa S. Yoshizato T, Nannya Y, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Suzuki H, Nagata Y, Sato Y, Kakiuchi N, Matsuo K, Onizuka M, Kataoka K, Chiba K, Tanaka H, Ueno H, Nakagawa M.M, Przychodzen B, Haferlach C, Kern W, Aoki K, Itonaga H, Kanda Y, Sekeres M.A, Maciejewski J.P, Haferlach T, Miyazaki Y, Horibe K, Sanada M, Miyano S, Makishima H, Ogawa S. Yoshizato T, Nannya Y, Atsuta Y, Shiozawa Y, Iijima-Yamashita Y, Yoshida K, Shiraishi Y, Suzuki H, Nagata Y, Sato Y, Kakiuchi N, Matsuo K, Onizuka M, Kataoka K, Chiba K, Tanaka H, Ueno H, Nakagawa M.M, Przychodzen B, Haferlach C, Kern W, Aoki K, Itonaga H, Kanda Y, Sekeres M.A, Maciejewski J.P, Haferlach T, Miyazaki Y, Horibe K, Sanada M, Miyano S, Makishima H, Ogawa S. Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: Impact on outcome of stem cell transplantation Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: Impact on outcome of stem cell transplantation Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: Impact on outcome of stem cell transplantation Blood, 129, 17, 2347-2358 Blood, 129, 17, 2347-2358 Blood, 129, 17, 2347-2358 2017 公開
Lu K, Nakagawa M.M, Thummar K, Rathinam C.V. Lu K, Nakagawa M.M, Thummar K, Rathinam C.V. Lu K, Nakagawa M.M, Thummar K, Rathinam C.V. Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence Slicer Endonuclease Argonaute 2 Is a Negative Regulator of Hematopoietic Stem Cell Quiescence Stem Cells, 34, 5, 1343-1353 Stem Cells, 34, 5, 1343-1353 Stem Cells, 34, 5, 1343-1353 2016 公開
Nakagawa M.M, Thummar K, Mandelbaum J, Pasqualucci L, Rathinam C.V. Nakagawa M.M, Thummar K, Mandelbaum J, Pasqualucci L, Rathinam C.V. Nakagawa M.M, Thummar K, Mandelbaum J, Pasqualucci L, Rathinam C.V. Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence Journal of Experimental Medicine, 212, 2, 203-216 Journal of Experimental Medicine, 212, 2, 203-216 Journal of Experimental Medicine, 212, 2, 203-216 2015 公開
Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M. Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M. Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M. Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia Oncogene, 33, 42, 5028-5038 Oncogene, 33, 42, 5028-5038 Oncogene, 33, 42, 5028-5038 2014 公開
Ueda K, Yoshimi A, Kagoya Y, Nishikawa S, Marquez V.E, Nakagawa M, Kurokawa M. Ueda K, Yoshimi A, Kagoya Y, Nishikawa S, Marquez V.E, Nakagawa M, Kurokawa M. Ueda K, Yoshimi A, Kagoya Y, Nishikawa S, Marquez V.E, Nakagawa M, Kurokawa M. Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16 Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16 Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16 Cancer Science, 105, 5, 512-519 Cancer Science, 105, 5, 512-519 Cancer Science, 105, 5, 512-519 2014 公開
Shinohara A, Imai Y, Nakagawa M, Takahashi T, Ichikawa M, Kurokawa M. Shinohara A, Imai Y, Nakagawa M, Takahashi T, Ichikawa M, Kurokawa M. Shinohara A, Imai Y, Nakagawa M, Takahashi T, Ichikawa M, Kurokawa M. Intracellular reactive oxygen species mark and influence the megakaryocyte-erythrocyte progenitor fate of common myeloid progenitors Intracellular reactive oxygen species mark and influence the megakaryocyte-erythrocyte progenitor fate of common myeloid progenitors Intracellular reactive oxygen species mark and influence the megakaryocyte-erythrocyte progenitor fate of common myeloid progenitors Stem Cells, 32, 2, 548-557 Stem Cells, 32, 2, 548-557 Stem Cells, 32, 2, 548-557 2014 公開
Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M. Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M. Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M. Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity Journal of Clinical Investigation, 124, 2, 528-542 Journal of Clinical Investigation, 124, 2, 528-542 Journal of Clinical Investigation, 124, 2, 528-542 2014 公開
Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M. Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M. Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M. Recurrent CDC25C mutations drive malignant transformation in FPD/AML Recurrent CDC25C mutations drive malignant transformation in FPD/AML Recurrent CDC25C mutations drive malignant transformation in FPD/AML Nature Communications, 5 Nature Communications, 5 Nature Communications, 5 2014 公開
Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, Kurokawa M. Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, Kurokawa M. Ichikawa M, Yoshimi A, Nakagawa M, Nishimoto N, Watanabe-Okochi N, Kurokawa M. A role for RUNX1 in hematopoiesis and myeloid leukemia A role for RUNX1 in hematopoiesis and myeloid leukemia A role for RUNX1 in hematopoiesis and myeloid leukemia International Journal of Hematology, 97, 6, 726-734 International Journal of Hematology, 97, 6, 726-734 International Journal of Hematology, 97, 6, 726-734 2013 公開
Hangai S, Nakamura F, Kamikubo Y, Honda A, Arai S, Nakagawa M, Ichikawa M, Kurokawa M. Hangai S, Nakamura F, Kamikubo Y, Honda A, Arai S, Nakagawa M, Ichikawa M, Kurokawa M. Hangai S, Nakamura F, Kamikubo Y, Honda A, Arai S, Nakagawa M, Ichikawa M, Kurokawa M. Erythroleukemia showing early erythroid and cytogenetic responses to azacitidine therapy Erythroleukemia showing early erythroid and cytogenetic responses to azacitidine therapy Erythroleukemia showing early erythroid and cytogenetic responses to azacitidine therapy Annals of Hematology, 92, 5, 707-709 Annals of Hematology, 92, 5, 707-709 Annals of Hematology, 92, 5, 707-709 2013 公開
Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link K.A, Mizukawa B, Grimes H.L, Kurokawa M, Liu P.P, Huang G, Mulloy J.C. Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link K.A, Mizukawa B, Grimes H.L, Kurokawa M, Liu P.P, Huang G, Mulloy J.C. Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link K.A, Mizukawa B, Grimes H.L, Kurokawa M, Liu P.P, Huang G, Mulloy J.C. Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells Journal of Clinical Investigation, 123, 9, 3876-3888 Journal of Clinical Investigation, 123, 9, 3876-3888 Journal of Clinical Investigation, 123, 9, 3876-3888 2013 公開
Yamazaki S, Nakamura F, Nannya Y, Nakagawa M, Ichikawa M, Kurokawa M. Yamazaki S, Nakamura F, Nannya Y, Nakagawa M, Ichikawa M, Kurokawa M. Yamazaki S, Nakamura F, Nannya Y, Nakagawa M, Ichikawa M, Kurokawa M. Early-onset Therapy-related Myelodysplastic Syndrome Originating from Prolonged Myelosuppression after Fludarabine-based Therapy Early-onset Therapy-related Myelodysplastic Syndrome Originating from Prolonged Myelosuppression after Fludarabine-based Therapy Early-onset Therapy-related Myelodysplastic Syndrome Originating from Prolonged Myelosuppression after Fludarabine-based Therapy Internal Medicine, 51, 24, 3427-3430 Internal Medicine, 51, 24, 3427-3430 Internal Medicine, 51, 24, 3427-3430 2012 公開
Yoshimi M, Goyama S, Kawazu M, Nakagawa M, Ichikawa M, Imai Y, Kumano K, Asai T, Mulloy J.C, Kraft A.S, Takahashi T, Shirafuji N, Kurokawa M. Yoshimi M, Goyama S, Kawazu M, Nakagawa M, Ichikawa M, Imai Y, Kumano K, Asai T, Mulloy J.C, Kraft A.S, Takahashi T, Shirafuji N, Kurokawa M. Yoshimi M, Goyama S, Kawazu M, Nakagawa M, Ichikawa M, Imai Y, Kumano K, Asai T, Mulloy J.C, Kraft A.S, Takahashi T, Shirafuji N, Kurokawa M. Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation European Journal of Immunology, 42, 4, 1044-1050 European Journal of Immunology, 42, 4, 1044-1050 European Journal of Immunology, 42, 4, 1044-1050 2012 公開
Toya T, Nishimoto N, Koya J, Nakagawa M, Nakamura F, Kandabashi K, Yamamoto G, Nannya Y, Ichikawa M, Kurokawa M. Toya T, Nishimoto N, Koya J, Nakagawa M, Nakamura F, Kandabashi K, Yamamoto G, Nannya Y, Ichikawa M, Kurokawa M. Toya T, Nishimoto N, Koya J, Nakagawa M, Nakamura F, Kandabashi K, Yamamoto G, Nannya Y, Ichikawa M, Kurokawa M. The first case of blastic plasmacytoid dendritic cell neoplasm with MLL-ENL rearrangement The first case of blastic plasmacytoid dendritic cell neoplasm with MLL-ENL rearrangement The first case of blastic plasmacytoid dendritic cell neoplasm with MLL-ENL rearrangement Leukemia Research, 36, 1, 117-118 Leukemia Research, 36, 1, 117-118 Leukemia Research, 36, 1, 117-118 2012 公開
Nakagawa M, Shimabe M, Watanabe-Okochi N, Arai S, Yoshimi A, Shinohara A, Nishimoto N, Kataoka K, Sato T, Kumano K, Nannya Y, Ichikawa M, Imai Y, Kurokawa M. Nakagawa M, Shimabe M, Watanabe-Okochi N, Arai S, Yoshimi A, Shinohara A, Nishimoto N, Kataoka K, Sato T, Kumano K, Nannya Y, Ichikawa M, Imai Y, Kurokawa M. Nakagawa M, Shimabe M, Watanabe-Okochi N, Arai S, Yoshimi A, Shinohara A, Nishimoto N, Kataoka K, Sato T, Kumano K, Nannya Y, Ichikawa M, Imai Y, Kurokawa M. AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors Blood, 118, 25, 6626-6637 Blood, 118, 25, 6626-6637 Blood, 118, 25, 6626-6637 2011 公開
Koya J, Nannya Y, Yoshizato T, Ono K, Seo S, Nakagawa M, Ichikawa M, Kurokawa M. Koya J, Nannya Y, Yoshizato T, Ono K, Seo S, Nakagawa M, Ichikawa M, Kurokawa M. Koya J, Nannya Y, Yoshizato T, Ono K, Seo S, Nakagawa M, Ichikawa M, Kurokawa M. Disseminated tuberculosis following unrelated cord blood transplantation for refractory peripheral T-cell lymphoma: Clinical role of serum procalcitonin levels Disseminated tuberculosis following unrelated cord blood transplantation for refractory peripheral T-cell lymphoma: Clinical role of serum procalcitonin levels Disseminated tuberculosis following unrelated cord blood transplantation for refractory peripheral T-cell lymphoma: Clinical role of serum procalcitonin levels Journal of Infection, 62, 3, 237-240 Journal of Infection, 62, 3, 237-240 Journal of Infection, 62, 3, 237-240 2011 公開
Arai S, Yoshimi A, Shimabe M, Ichikawa M, Nakagawa M, Imai Y, Goyama S, Kurokawa M. Arai S, Yoshimi A, Shimabe M, Ichikawa M, Nakagawa M, Imai Y, Goyama S, Kurokawa M. Arai S, Yoshimi A, Shimabe M, Ichikawa M, Nakagawa M, Imai Y, Goyama S, Kurokawa M. Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells Blood, 117, 23, 6304-6314 Blood, 117, 23, 6304-6314 Blood, 117, 23, 6304-6314 2011 公開
Kataoka K, Sato T, Yoshimi A, Goyama S, Tsuruta T, Kobayashi H, Shimabe M, Arai S, Nakagawa M, Imai Y, Kumano K, Kumagai K, Kubota N, Kadowaki T, Kurokawa M. Kataoka K, Sato T, Yoshimi A, Goyama S, Tsuruta T, Kobayashi H, Shimabe M, Arai S, Nakagawa M, Imai Y, Kumano K, Kumagai K, Kubota N, Kadowaki T, Kurokawa M. Kataoka K, Sato T, Yoshimi A, Goyama S, Tsuruta T, Kobayashi H, Shimabe M, Arai S, Nakagawa M, Imai Y, Kumano K, Kumagai K, Kubota N, Kadowaki T, Kurokawa M. Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity Journal of Experimental Medicine, 208, 12, 2403-2416 Journal of Experimental Medicine, 208, 12, 2403-2416 Journal of Experimental Medicine, 208, 12, 2403-2416 2011 公開
Yoshimi A, Goyama S, Watanabe-Okochi N, Yoshiki Y, Nannya Y, Nitta E, Arai S, Sato T, Shimabe M, Nakagawa M, Imai Y, Kitamura T, Kurokawa M. Yoshimi A, Goyama S, Watanabe-Okochi N, Yoshiki Y, Nannya Y, Nitta E, Arai S, Sato T, Shimabe M, Nakagawa M, Imai Y, Kitamura T, Kurokawa M. Yoshimi A, Goyama S, Watanabe-Okochi N, Yoshiki Y, Nannya Y, Nitta E, Arai S, Sato T, Shimabe M, Nakagawa M, Imai Y, Kitamura T, Kurokawa M. Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins Blood, 117, 13, 3617-3628 Blood, 117, 13, 3617-3628 Blood, 117, 13, 3617-3628 2011 公開
Nishimoto N, Arai S, Ichikawa M, Nakagawa M, Goyama S, Kumano K, Takahashi T, Kamikubo Y, Imai Y, Kurokawa M. Nishimoto N, Arai S, Ichikawa M, Nakagawa M, Goyama S, Kumano K, Takahashi T, Kamikubo Y, Imai Y, Kurokawa M. Nishimoto N, Arai S, Ichikawa M, Nakagawa M, Goyama S, Kumano K, Takahashi T, Kamikubo Y, Imai Y, Kurokawa M. Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19<sup>ARF</sup> Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19<sup>ARF</sup> Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19<sup>ARF</sup> Blood, 118, 9, 2541-2550 Blood, 118, 9, 2541-2550 Blood, 118, 9, 2541-2550 2011 公開
Tomomi Hashidate, Naoka Murakami, Masahiro Nakagawa, Motoshi Ichikawa, Mineo Kurokawa, Takao Shimizu, Motonao Nakamura Tomomi Hashidate, Naoka Murakami, Masahiro Nakagawa, Motoshi Ichikawa, Mineo Kurokawa, Takao Shimizu, Motonao Nakamura Tomomi Hashidate, Naoka Murakami, Masahiro Nakagawa, Motoshi Ichikawa, Mineo Kurokawa, Takao Shimizu, Motonao Nakamura AML1 enhances the expression of leukotriene B4 type-1 receptor in leukocytes AML1 enhances the expression of leukotriene B4 type-1 receptor in leukocytes AML1 enhances the expression of leukotriene B4 type-1 receptor in leukocytes The FASEB Journal, 24, 9, 3500 The FASEB Journal, 24, 9, 3500 The FASEB Journal, 24, 9, 3500 2010/09 公開
Nishimoto N, Imai Y, Ueda K, Nakagawa M, Shinohara A, Ichikawa M, Nannya Y, Kurokawa M. Nishimoto N, Imai Y, Ueda K, Nakagawa M, Shinohara A, Ichikawa M, Nannya Y, Kurokawa M. Nishimoto N, Imai Y, Ueda K, Nakagawa M, Shinohara A, Ichikawa M, Nannya Y, Kurokawa M. T cell acute lymphoblastic leukemia arising from familial platelet disorder T cell acute lymphoblastic leukemia arising from familial platelet disorder T cell acute lymphoblastic leukemia arising from familial platelet disorder International Journal of Hematology, 92, 1, 194-197 International Journal of Hematology, 92, 1, 194-197 International Journal of Hematology, 92, 1, 194-197 2010 公開
Nakagawa Masahiro, Goyama Susumu, Ichikawa Motoshi, Kurokawa Mineo Nakagawa Masahiro, Goyama Susumu, Ichikawa Motoshi, Kurokawa Mineo Nakagawa Masahiro, Goyama Susumu, Ichikawa Motoshi, Kurokawa Mineo The Pathogenetic Significance of Deregulated Transcription Factors in Hematological Malignancies The Pathogenetic Significance of Deregulated Transcription Factors in Hematological Malignancies The Pathogenetic Significance of Deregulated Transcription Factors in Hematological Malignancies Systems Biology, 193 Systems Biology, 193 Systems Biology, 193 2009 公開
Ichikawa M, Goyama S, Asai T, Kawazu M, Nakagawa M, Takeshita M, Chiba S, Ogawa S, Kurokawa M. Ichikawa M, Goyama S, Asai T, Kawazu M, Nakagawa M, Takeshita M, Chiba S, Ogawa S, Kurokawa M. Ichikawa M, Goyama S, Asai T, Kawazu M, Nakagawa M, Takeshita M, Chiba S, Ogawa S, Kurokawa M. AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis Journal of Immunology, 180, 7, 4402-4408 Journal of Immunology, 180, 7, 4402-4408 Journal of Immunology, 180, 7, 4402-4408 2008 公開
Sato T, Goyama S, Nitta E, Takeshita M, Yoshimi M, Nakagawa M, Kawazu M, Ichikawa M, Kurokawa M. Sato T, Goyama S, Nitta E, Takeshita M, Yoshimi M, Nakagawa M, Kawazu M, Ichikawa M, Kurokawa M. Sato T, Goyama S, Nitta E, Takeshita M, Yoshimi M, Nakagawa M, Kawazu M, Ichikawa M, Kurokawa M. Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-β signaling Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-β signaling Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-β signaling Cancer Science, 99, 7, 1407-1413 Cancer Science, 99, 7, 1407-1413 Cancer Science, 99, 7, 1407-1413 2008 公開
Kawazu M, Yamamoto G, Yoshimi M, Yamamoto K, Asai T, Ichikawa M, Seo S, Nakagawa M, Chiba S, Kurokawa M, Ogawa S. Kawazu M, Yamamoto G, Yoshimi M, Yamamoto K, Asai T, Ichikawa M, Seo S, Nakagawa M, Chiba S, Kurokawa M, Ogawa S. Kawazu M, Yamamoto G, Yoshimi M, Yamamoto K, Asai T, Ichikawa M, Seo S, Nakagawa M, Chiba S, Kurokawa M, Ogawa S. Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development Journal of Immunology, 179, 8, 5335-5345 Journal of Immunology, 179, 8, 5335-5345 Journal of Immunology, 179, 8, 5335-5345 2007 公開
Nakagawa M, Ichikawa M, Kumano K, Goyama S, Kawazu M, Asai T, Ogawa S, Kurokawa M, Chiba S. Nakagawa M, Ichikawa M, Kumano K, Goyama S, Kawazu M, Asai T, Ogawa S, Kurokawa M, Chiba S. Nakagawa M, Ichikawa M, Kumano K, Goyama S, Kawazu M, Asai T, Ogawa S, Kurokawa M, Chiba S. AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis Blood, 108, 10, 3329-3334 Blood, 108, 10, 3329-3334 Blood, 108, 10, 3329-3334 2006 公開
Asano-Mori Y, Oshima K, Sakata-Yanagimoto M, Nakagawa M, Kandabashi K, Izutsu K, Hangaishi A, Motokura T, Chiba S, Kurokawa M, Hirai H, Kanda Y. Asano-Mori Y, Oshima K, Sakata-Yanagimoto M, Nakagawa M, Kandabashi K, Izutsu K, Hangaishi A, Motokura T, Chiba S, Kurokawa M, Hirai H, Kanda Y. Asano-Mori Y, Oshima K, Sakata-Yanagimoto M, Nakagawa M, Kandabashi K, Izutsu K, Hangaishi A, Motokura T, Chiba S, Kurokawa M, Hirai H, Kanda Y. High-grade cytomegalovirus antigenemia after hematopoietic stem cell transplantation High-grade cytomegalovirus antigenemia after hematopoietic stem cell transplantation High-grade cytomegalovirus antigenemia after hematopoietic stem cell transplantation Bone Marrow Transplantation, 36, 9, 813-819 Bone Marrow Transplantation, 36, 9, 813-819 Bone Marrow Transplantation, 36, 9, 813-819 2005 公開
Kanda Y, Oshima K, Asano-Mori Y, Kandabashi K, Nakagawa M, Sakata-Yanagimoto M, Izutsu K, Hangaishi A, Tsujino S, Ogawa S, Motokura T, Chiba S, Hirai H. Kanda Y, Oshima K, Asano-Mori Y, Kandabashi K, Nakagawa M, Sakata-Yanagimoto M, Izutsu K, Hangaishi A, Tsujino S, Ogawa S, Motokura T, Chiba S, Hirai H. Kanda Y, Oshima K, Asano-Mori Y, Kandabashi K, Nakagawa M, Sakata-Yanagimoto M, Izutsu K, Hangaishi A, Tsujino S, Ogawa S, Motokura T, Chiba S, Hirai H. In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem-cell transplantation without ex vivo graft manipulation In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem-cell transplantation without ex vivo graft manipulation In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem-cell transplantation without ex vivo graft manipulation Transplantation, 79, 10, 1351-1357 Transplantation, 79, 10, 1351-1357 Transplantation, 79, 10, 1351-1357 2005 公開
Goyama S, Kanda Y, Nannya Y, Ogawa S, Asano-Moki Y, Ogawa N, Nakagawa M, Sakata-Yanagimoto M, Kawazu M, Komeno Y, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Aoki K, Chiba S, Motokura T, Hirai H. Goyama S, Kanda Y, Nannya Y, Ogawa S, Asano-Moki Y, Ogawa N, Nakagawa M, Sakata-Yanagimoto M, Kawazu M, Komeno Y, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Aoki K, Chiba S, Motokura T, Hirai H. Goyama S, Kanda Y, Nannya Y, Ogawa S, Asano-Moki Y, Ogawa N, Nakagawa M, Sakata-Yanagimoto M, Kawazu M, Komeno Y, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Aoki K, Chiba S, Motokura T, Hirai H. Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation Leukemia and Lymphoma, 45, 12, 2439-2443 Leukemia and Lymphoma, 45, 12, 2439-2443 Leukemia and Lymphoma, 45, 12, 2439-2443 2004 公開
Ogawa N, Kanda Y, Matsubara M, Asano Y, Nakagawa M, Sakata-Yanagimoto M, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Ogawa N, Kanda Y, Matsubara M, Asano Y, Nakagawa M, Sakata-Yanagimoto M, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Ogawa N, Kanda Y, Matsubara M, Asano Y, Nakagawa M, Sakata-Yanagimoto M, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion Bone Marrow Transplantation, 33, 5, 549-552 Bone Marrow Transplantation, 33, 5, 549-552 Bone Marrow Transplantation, 33, 5, 549-552 2004 公開
Sakata-Yanagimoto M, Kanda Y, Nakagawa M, Asano-Mori Y, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Chiba S, Motokura T, Hirai H. Sakata-Yanagimoto M, Kanda Y, Nakagawa M, Asano-Mori Y, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Chiba S, Motokura T, Hirai H. Sakata-Yanagimoto M, Kanda Y, Nakagawa M, Asano-Mori Y, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Chiba S, Motokura T, Hirai H. Predictors for severe cardiac complications after hematopoietic stem cell transplantation Predictors for severe cardiac complications after hematopoietic stem cell transplantation Predictors for severe cardiac complications after hematopoietic stem cell transplantation Bone Marrow Transplantation, 33, 10, 1043-1047 Bone Marrow Transplantation, 33, 10, 1043-1047 Bone Marrow Transplantation, 33, 10, 1043-1047 2004 公開
Goyama S, Yamaguchi Y, Imai Y, Kawazu M, Nakagawa M, Asai T, Kumano K, Mitani K, Ogawa S, Chiba S, Kurokawa M, Hirai H. Goyama S, Yamaguchi Y, Imai Y, Kawazu M, Nakagawa M, Asai T, Kumano K, Mitani K, Ogawa S, Chiba S, Kurokawa M, Hirai H. Goyama S, Yamaguchi Y, Imai Y, Kawazu M, Nakagawa M, Asai T, Kumano K, Mitani K, Ogawa S, Chiba S, Kurokawa M, Hirai H. The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region Blood, 104, 12, 3558-3564 Blood, 104, 12, 3558-3564 Blood, 104, 12, 3558-3564 2004 公開
Asano Y, Kanda Y, Ogawa N, Sakata-Yanagimoto M, Nakagawa M, Kawazu M, Goyama S, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Asano Y, Kanda Y, Ogawa N, Sakata-Yanagimoto M, Nakagawa M, Kawazu M, Goyama S, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Asano Y, Kanda Y, Ogawa N, Sakata-Yanagimoto M, Nakagawa M, Kawazu M, Goyama S, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H. Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation Bone Marrow Transplantation, 32, 12, 1175-1179 Bone Marrow Transplantation, 32, 12, 1175-1179 Bone Marrow Transplantation, 32, 12, 1175-1179 2003 公開

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外部資金:競争的資金・科学研究費補助金
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究(C) 代表 ハイスループットシングルセル RNAシーケンスによる残存病変の解析 (平成29年度分) 2017/04/01〜2018/03/31
基盤研究(C) 代表 ハイスループットシングルセル RNAシーケンスによる残存病変の解析 (平成30年度分) 2018/04/01〜2019/03/31