葛谷 聡

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氏名(漢字／フリガナ／アルファベット表記)
葛谷 聡／クズヤ アキラ／Kuzuya, Akira
所属部署・職名(部局／所属／講座等／職名)
医学研究科／医学専攻脳病態生理学講座臨床神経学／准教授
学部兼担
部局 所属 講座等 職名
医学部
連絡先住所
種別 住所(日本語) 住所(英語)
職場 〒606-8507 京都府京都市左京区聖護院川原町54 54 Shogoin-Kawahara-cho,Sakyo-ku,Kyoto 606-8507
連絡先電話番号
種別 番号
職場 075-751-3768
所属学会(国内)
学会名(日本語) 学会名(英語)
日本神経学会 Japanese Society of Neurology
日本内科学会 The Japanese Society of Internal Medicine
日本認知症学会 Japanese Society of Dementia Research
日本神経科学学会 The Japan Neuroscience Society
プロフィール
(英語)
I am a neurologist and a clinician-scientist who devotes my efforts to caring for patients with neurodegenerative diseases, including Alzheimer’s disease (AD) and clarifying AD pathogenesis through reverse translational research.
使用言語
言語名(japanese) 言語名(english) コード
英語 English eng
researchmap URL
https://researchmap.jp/kuzuya
研究テーマ
(日本語)
アルツハイマー病における活動依存性のシナプスAβ産生機構の解明
(英語)
A research to elucidate molecular mechanisms of synaptic Aβ production in Alzheimer’s disease
研究概要
(日本語)
近年の研究の成果により、アルツハイマー病のより早期の段階で生じる海馬過興奮が注目されている。アミロイドβ蛋白（Aβ）は神経活動に伴ってシナプスで産生、放出されるため、シナプスの過活動はアルツハイマー病におけるAβ沈着を抑制するための治療標的になり得る。現在、神経活動に伴うシナプスAβ産生の分子機構の解明をテーマに研究を進めている。さらに、AD患者に併存するてんかん発作の病態意義について着目し、脳波を用いた新規脳機能ADバイオマーカーの探索研究にも取り組んでいる。
(英語)
Recent studies shed light on hippocampal network hyperactivity as a very early event in Alzheimer’s disease (AD) patients. Since amyloid-β protein (Aβ) is produced and released locally at synapses in an activity-dependent manner, synaptic hyperactivity is considered as one of the promising therapeutic targets to prevent Aβ deposition in AD. Thus, my current interest in basic research is directed to molecular mechanisms regulating activity-dependent synaptic Aβ production. In addition, a clinical research is setting up to search for a novel brain functional biomarker using EEG, since my attention is paid to comorbidity of epileptic seizure in AD patients.
研究分野（キーワード）
キーワード(日本語) キーワード(英語)
アルツハイマー病、神経活動、アミロイドβ蛋白、シナプス Alzheimer's disease, neural activity, amyloid-β protein, synapse
論文
著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
Masakazu Miyamoto, Akira Kuzuya, Yasuha Noda, Sakiho Ueda, Megumi Asada-Utsugi, Shinji Ito, Yoshiyasu Fukusumi, Hiroshi Kawachi, Ryosuke Takahashi, Ayae Kinoshita Masakazu Miyamoto, Akira Kuzuya, Yasuha Noda, Sakiho Ueda, Megumi Asada-Utsugi, Shinji Ito, Yoshiyasu Fukusumi, Hiroshi Kawachi, Ryosuke Takahashi, Ayae Kinoshita Masakazu Miyamoto, Akira Kuzuya, Yasuha Noda, Sakiho Ueda, Megumi Asada-Utsugi, Shinji Ito, Yoshiyasu Fukusumi, Hiroshi Kawachi, Ryosuke Takahashi, Ayae Kinoshita Synaptic Vesicle Protein 2B Negatively Regulates the Amyloidogenic Processing of AβPP as a Novel Interaction Partner of BACE1. Synaptic Vesicle Protein 2B Negatively Regulates the Amyloidogenic Processing of AβPP as a Novel Interaction Partner of BACE1. Synaptic Vesicle Protein 2B Negatively Regulates the Amyloidogenic Processing of AβPP as a Novel Interaction Partner of BACE1. Journal of Alzheimer's disease : JAD, 75, 1, 173-185 Journal of Alzheimer's disease : JAD, 75, 1, 173-185 Journal of Alzheimer's disease : JAD, 75, 1, 173-185 2020 有 英語 公開
Takayuki Okano, Yosuke Yamamoto, Akira Kuzuya, Naohiro Egawa, Koji Kawakami, Ichiro Furuta, Kayoko Mizuno, Kiyohiro Fujino, Ken Kojima, Koichi Omori Takayuki Okano, Yosuke Yamamoto, Akira Kuzuya, Naohiro Egawa, Koji Kawakami, Ichiro Furuta, Kayoko Mizuno, Kiyohiro Fujino, Ken Kojima, Koichi Omori Takayuki Okano, Yosuke Yamamoto, Akira Kuzuya, Naohiro Egawa, Koji Kawakami, Ichiro Furuta, Kayoko Mizuno, Kiyohiro Fujino, Ken Kojima, Koichi Omori Development of the Reading Cognitive Test Kyoto (ReaCT Kyoto) for Early Detection of Cognitive Decline in Patients with Hearing Loss. Development of the Reading Cognitive Test Kyoto (ReaCT Kyoto) for Early Detection of Cognitive Decline in Patients with Hearing Loss. Development of the Reading Cognitive Test Kyoto (ReaCT Kyoto) for Early Detection of Cognitive Decline in Patients with Hearing Loss. Journal of Alzheimer's disease : JAD, 73, 3, 981-990 Journal of Alzheimer's disease : JAD, 73, 3, 981-990 Journal of Alzheimer's disease : JAD, 73, 3, 981-990 2020 有 英語 公開
上田 紗希帆, 武山 博文, 葛谷 聡, 松本 理器, 木下 彩栄, 陳 和夫, 高橋 良輔 上田 紗希帆, 武山 博文, 葛谷 聡, 松本 理器, 木下 彩栄, 陳 和夫, 高橋 良輔 睡眠時無呼吸症候群を合併するアルツハイマー病患者の睡眠時脳波における神経過剰興奮 睡眠時無呼吸症候群を合併するアルツハイマー病患者の睡眠時脳波における神経過剰興奮 臨床神経学, 59, Suppl., S268-S268 臨床神経学, 59, Suppl., S268-S268 , 59, Suppl., S268-S268 2019/11 有 日本語 公開
Li F, Takechi H, Saito R, Ayaki T, Kokuryu A, Kuzuya A, Takahashi R Li F, Takechi H, Saito R, Ayaki T, Kokuryu A, Kuzuya A, Takahashi R Li F, Takechi H, Saito R, Ayaki T, Kokuryu A, Kuzuya A, Takahashi R A comparative study: visual rating scores and the voxel-based specific regional analysis system for Alzheimer's disease on magnetic resonance imaging among subjects with Alzheimer's disease, mild cognitive impairment, and normal cognition. A comparative study: visual rating scores and the voxel-based specific regional analysis system for Alzheimer's disease on magnetic resonance imaging among subjects with Alzheimer's disease, mild cognitive impairment, and normal cognition. A comparative study: visual rating scores and the voxel-based specific regional analysis system for Alzheimer's disease on magnetic resonance imaging among subjects with Alzheimer's disease, mild cognitive impairment, and normal cognition. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 19, 2, 95-104 Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 19, 2, 95-104 Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 19, 2, 95-104 2019/03 有 公開
Tanabe Y, Taira T, Shimotake A, Inoue T, Awaya T, Kato T, Kuzuya A, Ikeda A, Takahashi R Tanabe Y, Taira T, Shimotake A, Inoue T, Awaya T, Kato T, Kuzuya A, Ikeda A, Takahashi R Tanabe Y, Taira T, Shimotake A, Inoue T, Awaya T, Kato T, Kuzuya A, Ikeda A, Takahashi R [An adult female with proline-rich transmembrane protein 2 related paroxysmal disorders manifesting paroxysmal kinesigenic choreoathetosis and epileptic seizures]. [An adult female with proline-rich transmembrane protein 2 related paroxysmal disorders manifesting paroxysmal kinesigenic choreoathetosis and epileptic seizures]. [An adult female with proline-rich transmembrane protein 2 related paroxysmal disorders manifesting paroxysmal kinesigenic choreoathetosis and epileptic seizures]. Rinsho shinkeigaku = Clinical neurology, 59, 3, 144-148 Rinsho shinkeigaku = Clinical neurology, 59, 3, 144-148 Rinsho shinkeigaku = Clinical neurology, 59, 3, 144-148 2019/03 有 公開
Nagano M, Kobayashi K, Yamada-Otani M, Kuzuya A, Matsumoto R, Oita J, Yoneda M, Ikeda A, Takahashi R Nagano M, Kobayashi K, Yamada-Otani M, Kuzuya A, Matsumoto R, Oita J, Yoneda M, Ikeda A, Takahashi R Nagano M, Kobayashi K, Yamada-Otani M, Kuzuya A, Matsumoto R, Oita J, Yoneda M, Ikeda A, Takahashi R Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis. Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis. Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis. Internal medicine (Tokyo, Japan), 58, 8, 1167-1172 Internal medicine (Tokyo, Japan), 58, 8, 1167-1172 Internal medicine (Tokyo, Japan), 58, 8, 1167-1172 2019 有 公開
Noda Y, Kuzuya A, Tanigawa K, Araki M, Kawai R, Ma B, Sasakura Y, Maesako M, Tashiro Y, Miyamoto M, Uemura K, Okuno Y, Kinoshita A Noda Y, Kuzuya A, Tanigawa K, Araki M, Kawai R, Ma B, Sasakura Y, Maesako M, Tashiro Y, Miyamoto M, Uemura K, Okuno Y, Kinoshita A Noda Y, Kuzuya A, Tanigawa K, Araki M, Kawai R, Ma B, Sasakura Y, Maesako M, Tashiro Y, Miyamoto M, Uemura K, Okuno Y, Kinoshita A Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer's disease. Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer's disease. Fibronectin type III domain-containing protein 5 interacts with APP and decreases amyloid β production in Alzheimer's disease. Molecular brain, 11, 1, 61 Molecular brain, 11, 1, 61 Molecular brain, 11, 1, 61 2018/10/24 有 公開
Sakai M, Ueda S, Daito T, Asada-Utsugi M, Komatsu Y, Kinoshita A, Maki T, Kuzuya A, Takahashi R, Makino A, Tomonaga K Sakai M, Ueda S, Daito T, Asada-Utsugi M, Komatsu Y, Kinoshita A, Maki T, Kuzuya A, Takahashi R, Makino A, Tomonaga K Sakai M, Ueda S, Daito T, Asada-Utsugi M, Komatsu Y, Kinoshita A, Maki T, Kuzuya A, Takahashi R, Makino A, Tomonaga K Degradation of amyloid β peptide by neprilysin expressed from Borna disease virus vector. Degradation of amyloid β peptide by neprilysin expressed from Borna disease virus vector. Degradation of amyloid β peptide by neprilysin expressed from Borna disease virus vector. Microbiology and immunology Microbiology and immunology Microbiology and immunology 2018/05 有 公開
Wang X, Kastanenka KV, Arbel-Ornath M, Commins C, Kuzuya A, Lariviere AJ, Krafft GA, Hefti F, Jerecic J, Bacskai BJ Wang X, Kastanenka KV, Arbel-Ornath M, Commins C, Kuzuya A, Lariviere AJ, Krafft GA, Hefti F, Jerecic J, Bacskai BJ Wang X, Kastanenka KV, Arbel-Ornath M, Commins C, Kuzuya A, Lariviere AJ, Krafft GA, Hefti F, Jerecic J, Bacskai BJ An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging. An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging. An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging. Scientific reports, 8, 1, 4634 Scientific reports, 8, 1, 4634 Scientific reports, 8, 1, 4634 2018/03 有 公開
長野 眞大, 小板 夏子, 綾木 孝, 北野 俊行, 葛谷 聡, 松本 理器, 高折 晃史, 池田 昭夫, 高橋 良輔 長野 眞大, 小板 夏子, 綾木 孝, 北野 俊行, 葛谷 聡, 松本 理器, 高折 晃史, 池田 昭夫, 高橋 良輔 悪性リンパ腫の治療後にCLIPPERSを発症した一例 悪性リンパ腫の治療後にCLIPPERSを発症した一例 臨床神経学, 57, 10, 657-657 臨床神経学, 57, 10, 657-657 , 57, 10, 657-657 2017/10 有 日本語 公開
Ma Alma E. Carandang, Naoko Takamatsu, Hiroyuki Nodera, Atsuko Mori, Naoya Mimura, Nobuhisa Okada, Hisanori Kinoshita, Akira Kuzuya, Makoto Urushitani, Ryosuke Takahashi, Yuishin Izumi, Ryuji Kaji Ma Alma E. Carandang, Naoko Takamatsu, Hiroyuki Nodera, Atsuko Mori, Naoya Mimura, Nobuhisa Okada, Hisanori Kinoshita, Akira Kuzuya, Makoto Urushitani, Ryosuke Takahashi, Yuishin Izumi, Ryuji Kaji Ma Alma E. Carandang, Naoko Takamatsu, Hiroyuki Nodera, Atsuko Mori, Naoya Mimura, Nobuhisa Okada, Hisanori Kinoshita, Akira Kuzuya, Makoto Urushitani, Ryosuke Takahashi, Yuishin Izumi, Ryuji Kaji Velocity of intraneural blood flow is increased in inflammatory neuropathies: sonographic observation Velocity of intraneural blood flow is increased in inflammatory neuropathies: sonographic observation Velocity of intraneural blood flow is increased in inflammatory neuropathies: sonographic observation JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 88, 5, 455-+ JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 88, 5, 455-+ JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 88, 5, 455-+ 2017/05 有 英語 公開
Akira Kuzuya, Katarzyna M. Zoltowska, Kathryn L. Post, Muriel Arimon, Xuejing Li, Sarah Svirsky, Masato Maesako, Alona Muzikansky, Vivek Gautam, Dora Kovacs, Bradley T. Hyman, Oksana Berezovska Akira Kuzuya, Katarzyna M. Zoltowska, Kathryn L. Post, Muriel Arimon, Xuejing Li, Sarah Svirsky, Masato Maesako, Alona Muzikansky, Vivek Gautam, Dora Kovacs, Bradley T. Hyman, Oksana Berezovska Akira Kuzuya, Katarzyna M. Zoltowska, Kathryn L. Post, Muriel Arimon, Xuejing Li, Sarah Svirsky, Masato Maesako, Alona Muzikansky, Vivek Gautam, Dora Kovacs, Bradley T. Hyman, Oksana Berezovska Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta BMC BIOLOGY, 14, 25 BMC BIOLOGY, 14, 25 BMC BIOLOGY, 14, 25 2016/03 有 英語 研究論文(学術雑誌) 公開
Honda Y, Otsuka A, Egawa G, Inoue Y, Kuzuya A, Takahashi R, Miyachi Y, Kabashima K Honda Y, Otsuka A, Egawa G, Inoue Y, Kuzuya A, Takahashi R, Miyachi Y, Kabashima K Honda Y, Otsuka A, Egawa G, Inoue Y, Kuzuya A, Takahashi R, Miyachi Y, Kabashima K Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis. Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis. Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis. European journal of dermatology : EJD, 25, 5, 487-488 European journal of dermatology : EJD, 25, 5, 487-488 European journal of dermatology : EJD, 25, 5, 487-488 2015/09 有 公開
Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Haruhiko Akiyama, Ryosuke Takahashi, Takeshi Kihara, Shun Shimohama, Ayae Kinoshita Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Haruhiko Akiyama, Ryosuke Takahashi, Takeshi Kihara, Shun Shimohama, Ayae Kinoshita Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Haruhiko Akiyama, Ryosuke Takahashi, Takeshi Kihara, Shun Shimohama, Ayae Kinoshita Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling JOURNAL OF NEUROCHEMISTRY, 121, 6, 964-973 JOURNAL OF NEUROCHEMISTRY, 121, 6, 964-973 JOURNAL OF NEUROCHEMISTRY, 121, 6, 964-973 2012/06 有 英語 研究論文(学術雑誌) 公開
Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Hayashida N, Asada-Utsugi M, Watanabe K, Uemura M, Kihara T, Takahashi R, Shimohama S, Kinoshita A Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Hayashida N, Asada-Utsugi M, Watanabe K, Uemura M, Kihara T, Takahashi R, Shimohama S, Kinoshita A Masato Maesako, Kengo Uemura, Masakazu Kubota, Akira Kuzuya, Kazuki Sasaki, Naoko Hayashida, Megumi Asada-Utsugi, Kiwamu Watanabe, Maiko Uemura, Takeshi Kihara, Ryosuke Takahashi, Shun Shimohama, Ayae Kinoshita Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice. Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice. Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced beta-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice The Journal of biological chemistry, 287, 27, 23024-23033 The Journal of biological chemistry, 287, 27, 23024-23033 JOURNAL OF BIOLOGICAL CHEMISTRY, 287, 27, 23024-23033 2012/06 有 英語 研究論文(学術雑誌) 公開
Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, Shimohama S, Kihara T, Kinoshita A Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Asada M, Watanabe K, Hayashida N, Ihara M, Ito H, Shimohama S, Kihara T, Kinoshita A Masato Maesako, Kengo Uemura, Masakazu Kubota, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Naoko Hayashida, Masafumi Ihara, Hidefumi Ito, Shun Shimohama, Takeshi Kihara, Ayae Kinoshita Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice. Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice. Environmental enrichment ameliorated high-fat diet-induced A beta deposition and memory deficit in APP transgenic mice Neurobiology of aging, 33, 5, 1011.e11-23 Neurobiology of aging, 33, 5, 1011.e11-23 NEUROBIOLOGY OF AGING, 33, 5, 1011.e11-23 2012/05 有 英語 研究論文(学術雑誌) 公開
Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A Megumi Asada-Utsugi, Kengo Uemura, Yasuha Noda, Akira Kuzuya, Masato Maesako, Koichi Ando, Masakazu Kubota, Kiwamu Watanabe, Makio Takahashi, Takeshi Kihara, Shun Shimohama, Ryosuke Takahashi, Oksana Berezovska, Ayae Kinoshita N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production. N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production. N-cadherin enhances APP dimerization at the extracellular domain and modulates A beta production Journal of neurochemistry, 119, 2, 354-363 Journal of neurochemistry, 119, 2, 354-363 JOURNAL OF NEUROCHEMISTRY, 119, 2, 354-363 2011/10 有 英語 研究論文(学術雑誌) 公開
Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Ayae Kinoshita Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Ayae Kinoshita Masato Maesako, Kengo Uemura, Akira Kuzuya, Kazuki Sasaki, Megumi Asada, Kiwamu Watanabe, Koichi Ando, Masakazu Kubota, Takeshi Kihara, Ayae Kinoshita Presenilin Regulates Insulin Signaling via a gamma-Secretase-independent Mechanism Presenilin Regulates Insulin Signaling via a gamma-Secretase-independent Mechanism Presenilin Regulates Insulin Signaling via a gamma-Secretase-independent Mechanism JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 28, 25309-25316 JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 28, 25309-25316 JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 28, 25309-25316 2011/07 有 英語 研究論文(学術雑誌) 公開
M. Maesako, K. Uemura, M. Kubota, K. Hiyoshi, K. Ando, A. Kuzuya, T. Kihara, M. Asada, H. Akiyama, A. Kinoshita M. Maesako, K. Uemura, M. Kubota, K. Hiyoshi, K. Ando, A. Kuzuya, T. Kihara, M. Asada, H. Akiyama, A. Kinoshita Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage EFFECT OF GLYCOGEN SYNTHASE KINASE 3 beta-MEDIATED PRESENILIN 1 PHOSPHORYLATION ON AMYLOID beta PRODUCTION IS NEGATIVELY REGULATED BY INSULIN RECEPTOR CLEAVAGE Neuroscience, 177, 298-307 Neuroscience, 177, 298-307 NEUROSCIENCE, 177, 298-307 2011/03 有 英語 研究論文(学術雑誌) 公開
Koichi Ando, Kengo Uemura, Akira Kuzuya, Masato Maesako, Megumi Asada-Utsugi, Masakazu Kubota, Nobuhisa Aoyagi, Katsuji Yoshioka, Katsuya Okawa, Haruhisa Inoue, Jun Kawamata, Shun Shimohama, Tetsuaki Arai, Ryosuke Takahashi, Ayae Kinoshita Koichi Ando, Kengo Uemura, Akira Kuzuya, Masato Maesako, Megumi Asada-Utsugi, Masakazu Kubota, Nobuhisa Aoyagi, Katsuji Yoshioka, Katsuya Okawa, Haruhisa Inoue, Jun Kawamata, Shun Shimohama, Tetsuaki Arai, Ryosuke Takahashi, Ayae Kinoshita Koichi Ando, Kengo Uemura, Akira Kuzuya, Masato Maesako, Megumi Asada-Utsugi, Masakazu Kubota, Nobuhisa Aoyagi, Katsuji Yoshioka, Katsuya Okawa, Haruhisa Inoue, Jun Kawamata, Shun Shimohama, Tetsuaki Arai, Ryosuke Takahashi, Ayae Kinoshita N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein IMPLICATIONS FOR NEURODEGENERATION IN ALZHEIMER DISEASE N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein IMPLICATIONS FOR NEURODEGENERATION IN ALZHEIMER DISEASE N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein IMPLICATIONS FOR NEURODEGENERATION IN ALZHEIMER DISEASE JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 9, 7619-7628 JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 9, 7619-7628 JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 9, 7619-7628 2011/03 有 英語 研究論文(学術雑誌) 公開
A. Kuzuya, A. Kinoshita, K. Uemura A. Kuzuya, A. Kinoshita, K. Uemura A. Kuzuya, A. Kinoshita, K. Uemura Insight into \\'Synaptopathy\\' in Alzheimer\\'s Disease: From Lifestyle to PS1/N-Cadherin Interaction Insight into \\'Synaptopathy\\' in Alzheimer\\'s Disease: From Lifestyle to PS1/N-Cadherin Interaction Insight into \\'Synaptopathy\\' in Alzheimer\\'s Disease: From Lifestyle to PS1/N-Cadherin Interaction Alzheimer\\'s Disease Research Journal, 3, 1, 47-56 Alzheimer\\'s Disease Research Journal, 3, 1, 47-56 Alzheimer\\'s Disease Research Journal, 3, 1, 47-56 2011 有 英語 公開
Megumi Asada, Kengo Uemura, Akira Kuzuya, Masato Maesako, Masakazu Kubota, Kiwamu Watanabe, Takeshi Kihara, Shun Shimohama, Ryosuke Takahashi, Oksana Berezovska, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Masato Maesako, Masakazu Kubota, Kiwamu Watanabe, Takeshi Kihara, Shun Shimohama, Ryosuke Takahashi, Oksana Berezovska, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Masato Maesako, Masakazu Kubota, Kiwamu Watanabe, Takeshi Kihara, Shun Shimohama, Ryosuke Takahashi, Oksana Berezovska, Ayae Kinoshita N-cadherin enhances APP dimerization at the extracellular domain and modulates A beta production N-cadherin enhances APP dimerization at the extracellular domain and modulates A beta production N-cadherin enhances APP dimerization at the extracellular domain and modulates A beta production NEUROSCIENCE RESEARCH, 71, E392-E392 NEUROSCIENCE RESEARCH, 71, E392-E392 NEUROSCIENCE RESEARCH, 71, E392-E392 2011 有 英語 公開
Masato Maesako, Kazuki Sasaki, Akira Kuzuya, Megumi Asada, Masakazu Kubota, Koichi Ando, Masafumi Ihara, Hidefumi Ito, Takeshi Kihara, Kengo Uemura, Ayae Kinoshita Masato Maesako, Kazuki Sasaki, Akira Kuzuya, Megumi Asada, Masakazu Kubota, Koichi Ando, Masafumi Ihara, Hidefumi Ito, Takeshi Kihara, Kengo Uemura, Ayae Kinoshita Environmental Enrichment ameliorates high fat diet induced memory deficit and β-amyloidosis Environmental Enrichment ameliorates high fat diet induced memory deficit and β-amyloidosis Environmental Enrichment ameliorates high fat diet induced memory deficit and beta-amyloidosis NEUROSCIENCE RESEARCH, 71, E288-E288 , 71, E288-E288 NEUROSCIENCE RESEARCH, 71, E288-E288 2011 有 英語 公開
Masato Maesako, Kengo Uemura, Masakazu Kubota, Koichi Ando, Akira Kuzuya, Megumi Asada, Takeshi Kihara, Ayae Kinoshita Masato Maesako, Kengo Uemura, Masakazu Kubota, Koichi Ando, Akira Kuzuya, Megumi Asada, Takeshi Kihara, Ayae Kinoshita Masato Maesako, Kengo Uemura, Masakazu Kubota, Koichi Ando, Akira Kuzuya, Megumi Asada, Takeshi Kihara, Ayae Kinoshita Insulin regulates Presenilin 1 localization via PI3K/Akt signaling Insulin regulates Presenilin 1 localization via PI3K/Akt signaling Insulin regulates Presenilin 1 localization via PI3K/Akt signaling NEUROSCIENCE LETTERS, 483, 3, 157-161 NEUROSCIENCE LETTERS, 483, 3, 157-161 NEUROSCIENCE LETTERS, 483, 3, 157-161 2010/10 有 英語 研究論文(学術雑誌) 公開
Ando Koichi, Watanabe Kiwamu, Maesako Masato, Asada Megumi, Kubota Masakazu, Aoyagi Nobuhisa, Kuzuya Akira, Uemura Kengo, Kawamata Jun, Takahashi Ryosuke, Kinoshita Ayae Ando Koichi, Watanabe Kiwamu, Maesako Masato, Asada Megumi, Kubota Masakazu, Aoyagi Nobuhisa, Kuzuya Akira, Uemura Kengo, Kawamata Jun, Takahashi Ryosuke, Kinoshita Ayae Ando Koichi, Watanabe Kiwamu, Maesako Masato, Asada Megumi, Kubota Masakazu, Aoyagi Nobuhisa, Kuzuya Akira, Uemura Kengo, Kawamata Jun, Takahashi Ryosuke, Kinoshita Ayae Analysis of N-cadherin interacting proteins in Alzheimer's disease Analysis of N-cadherin interacting proteins in Alzheimer's disease Analysis of N-cadherin interacting proteins in Alzheimer's disease NEUROSCIENCE RESEARCH, 68, E67 NEUROSCIENCE RESEARCH, 68, E67 NEUROSCIENCE RESEARCH, 68, E67 2010 有 公開
Maesako Masato, Uemura Kengo, Kubota Masakazu, Ando Koichi, Kuzuya Akira, Asada Megumi, Yamada Nao, Akiyama Haruhiko, Kinoshita Ayae Maesako Masato, Uemura Kengo, Kubota Masakazu, Ando Koichi, Kuzuya Akira, Asada Megumi, Yamada Nao, Akiyama Haruhiko, Kinoshita Ayae Maesako Masato, Uemura Kengo, Kubota Masakazu, Ando Koichi, Kuzuya Akira, Asada Megumi, Yamada Nao, Akiyama Haruhiko, Kinoshita Ayae Effects of presenilin 1 phosphorylation on insulin receptor Effects of presenilin 1 phosphorylation on insulin receptor Effects of presenilin 1 phosphorylation on insulin receptor NEUROSCIENCE RESEARCH, 68, E188-E189 NEUROSCIENCE RESEARCH, 68, E188-E189 NEUROSCIENCE RESEARCH, 68, E188-E189 2010 有 公開
Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Takeshi Kihara, Jun Kawamata, Shun Shimohama, Ayae Kinoshita, Ryosuke Takahashi Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Takeshi Kihara, Jun Kawamata, Shun Shimohama, Ayae Kinoshita, Ryosuke Takahashi Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Takeshi Kihara, Jun Kawamata, Shun Shimohama, Ayae Kinoshita, Ryosuke Takahashi PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity PI3K inhibition causes the accumulation of ubiquitinated presenilin 1 without affecting the proteasome activity BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 391, 2, 1240-1245 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 391, 2, 1240-1245 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 391, 2, 1240-1245 2010/01 有 英語 研究論文(学術雑誌) 公開
Maesako Masato, Uemura Kengo, Kubota Masakazu, Kuzuya Akira, Ando Koichi, Ikeuchi Takeshi, Asada Megumi, Kinoshita Ayae Maesako Masato, Uemura Kengo, Kubota Masakazu, Kuzuya Akira, Ando Koichi, Ikeuchi Takeshi, Asada Megumi, Kinoshita Ayae Maesako Masato, Uemura Kengo, Kubota Masakazu, Kuzuya Akira, Ando Koichi, Ikeuchi Takeshi, Asada Megumi, Kinoshita Ayae Functional regulation of Presenilin1 via insulin signaling Functional regulation of Presenilin1 via insulin signaling Functional regulation of Presenilin1 via insulin signaling NEUROSCIENCE RESEARCH, 65, S115 NEUROSCIENCE RESEARCH, 65, S115 NEUROSCIENCE RESEARCH, 65, S115 2009 有 公開
Yoshimura H, Imai Y, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kawamoto M, Kohara N Yoshimura H, Imai Y, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kawamoto M, Kohara N Yoshimura H, Imai Y, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kawamoto M, Kohara N [Elderly autopsy case of influenza-associated encephalopathy]. [Elderly autopsy case of influenza-associated encephalopathy]. [Elderly autopsy case of influenza-associated encephalopathy]. Rinsho shinkeigaku = Clinical neurology, 48, 10, 713-720 Rinsho shinkeigaku = Clinical neurology, 48, 10, 713-720 Rinsho shinkeigaku = Clinical neurology, 48, 10, 713-720 2008/10 有 公開
Yoshimura H, Takano S, Kawamoto M, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kohara N Yoshimura H, Takano S, Kawamoto M, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kohara N Yoshimura H, Takano S, Kawamoto M, Beppu M, Ohara N, Kobayashi J, Kuzuya A, Yamagami H, Kohara N [Clinical characteristics of status epilepticus in an emergency hospital: importance of nonconvulsive status epilepticus]. [Clinical characteristics of status epilepticus in an emergency hospital: importance of nonconvulsive status epilepticus]. [Clinical characteristics of status epilepticus in an emergency hospital: importance of nonconvulsive status epilepticus]. Rinsho shinkeigaku = Clinical neurology, 48, 4, 242-248 Rinsho shinkeigaku = Clinical neurology, 48, 4, 242-248 Rinsho shinkeigaku = Clinical neurology, 48, 4, 242-248 2008/04 有 公開
Kengo Uemura, Akira Kuzuya, Yoshiharu Shimozono, Nobuhisa Aoyagi, Koichi Ando, Shun Shimohama, Ayae Kinoshita Kengo Uemura, Akira Kuzuya, Yoshiharu Shimozono, Nobuhisa Aoyagi, Koichi Ando, Shun Shimohama, Ayae Kinoshita Kengo Uemura, Akira Kuzuya, Yoshiharu Shimozono, Nobuhisa Aoyagi, Koichi Ando, Shun Shimohama, Ayae Kinoshita GSK3 beta activity modifies the localization and function of presenilin 1 GSK3 beta activity modifies the localization and function of presenilin 1 GSK3 beta activity modifies the localization and function of presenilin 1 JOURNAL OF BIOLOGICAL CHEMISTRY, 282, 21, 15823-15832 JOURNAL OF BIOLOGICAL CHEMISTRY, 282, 21, 15823-15832 JOURNAL OF BIOLOGICAL CHEMISTRY, 282, 21, 15823-15832 2007/05 有 英語 研究論文(学術雑誌) 公開
K. Uemura, A. Kuzuya, N. Aoyagi, K. Ando, Y. Shimozono, H. Ninomiya, S. Shimohama, A. Kinoshita K. Uemura, A. Kuzuya, N. Aoyagi, K. Ando, Y. Shimozono, H. Ninomiya, S. Shimohama, A. Kinoshita K. Uemura, A. Kuzuya, N. Aoyagi, K. Ando, Y. Shimozono, H. Ninomiya, S. Shimohama, A. Kinoshita Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor Amyloid beta inhibits ectodomain shedding of N-cadherin via down-regulation of cell-surface NMDA receptor NEUROSCIENCE, 145, 1, 5-10 NEUROSCIENCE, 145, 1, 5-10 NEUROSCIENCE, 145, 1, 5-10 2007/03 有 英語 研究論文(学術雑誌) 公開
Akira Kuzuya, Kengo Uemura, Naoyuki Kitagawa, Nobuhisa Aoyagi, Takeshi Kihara, Haruaki Ninomiya, Shoichi Ishiura, Ryosuke Takahashi, Shun Shimohama Akira Kuzuya, Kengo Uemura, Naoyuki Kitagawa, Nobuhisa Aoyagi, Takeshi Kihara, Haruaki Ninomiya, Shoichi Ishiura, Ryosuke Takahashi, Shun Shimohama Akira Kuzuya, Kengo Uemura, Naoyuki Kitagawa, Nobuhisa Aoyagi, Takeshi Kihara, Haruaki Ninomiya, Shoichi Ishiura, Ryosuke Takahashi, Shun Shimohama Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1) JOURNAL OF NEUROSCIENCE RESEARCH, 85, 1, 153-165 JOURNAL OF NEUROSCIENCE RESEARCH, 85, 1, 153-165 JOURNAL OF NEUROSCIENCE RESEARCH, 85, 1, 153-165 2007/01 有 英語 研究論文(学術雑誌) 公開
K Uemura, T Kihara, A Kuzuya, K Okawa, T Nishimoto, H Nimomiya, H Sugimoto, A Kinoshita, S Shimohama K Uemura, T Kihara, A Kuzuya, K Okawa, T Nishimoto, H Nimomiya, H Sugimoto, A Kinoshita, S Shimohama K Uemura, T Kihara, A Kuzuya, K Okawa, T Nishimoto, H Nimomiya, H Sugimoto, A Kinoshita, S Shimohama Characterization of sequential N-cadherin cleavage by ADAM10 and PS1 Characterization of sequential N-cadherin cleavage by ADAM10 and PS1 Characterization of sequential N-cadherin cleavage by ADAM10 and PS1 NEUROSCIENCE LETTERS, 402, 3, 278-283 NEUROSCIENCE LETTERS, 402, 3, 278-283 NEUROSCIENCE LETTERS, 402, 3, 278-283 2006/07 有 英語 研究論文(学術雑誌) 公開
Kengo Uemura, Takeshi Kihara, Akira Kuzuya, Katsuya Okawa, Takaaki Nishimoto, Haruhiko Bito, Haruaki Ninomiya, Hachiro Sugimoto, Ayae Kinoshita, Shun Shimohama Kengo Uemura, Takeshi Kihara, Akira Kuzuya, Katsuya Okawa, Takaaki Nishimoto, Haruhiko Bito, Haruaki Ninomiya, Hachiro Sugimoto, Ayae Kinoshita, Shun Shimohama Kengo Uemura, Takeshi Kihara, Akira Kuzuya, Katsuya Okawa, Takaaki Nishimoto, Haruhiko Bito, Haruaki Ninomiya, Hachiro Sugimoto, Ayae Kinoshita, Shun Shimohama Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 345, 3, 951-958 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 345, 3, 951-958 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 345, 3, 951-958 2006/07 有 英語 研究論文(学術雑誌) 公開
Uemura K, Kihara T, Kuzuya A, Okawa K, Bito H, Ninomiya H, m, Sugimoto H, Shimohama S, Kinoshita A Uemura K, Kihara T, Kuzuya A, Okawa K, Bito H, Ninomiya H, m, Sugimoto H, Shimohama S, Kinoshita A Uemura K, Kihara T, Kuzuya A, Okawa K, Bito H, Ninomiya H, m, Sugimoto H, Shimohama S, Kinoshita A Modulation of beta-catenin nuclear signaling via epsilon-cleavafe of N-cadherin. Modulation of beta-catenin nuclear signaling via epsilon-cleavafe of N-cadherin. Modulation of beta-catenin nuclear signaling via epsilon-cleavafe of N-cadherin. Biochem Biophys Res Commun 345:945-8 Biochem Biophys Res Commun 345:945-8 Biochem Biophys Res Commun 345:945-8 2006 有 英語 公開
Kengo Uemura, Akira Kuzuya, Shun Shimohama Kengo Uemura, Akira Kuzuya, Shun Shimohama Kengo Uemura, Akira Kuzuya, Shun Shimohama Protein Trafficking and Alzheimer's Disease Protein Trafficking and Alzheimer's Disease Protein Trafficking and Alzheimer's Disease CURRENT ALZHEIMER RESEARCH, 1, 1, 1-10 CURRENT ALZHEIMER RESEARCH, 1, 1, 1-10 CURRENT ALZHEIMER RESEARCH, 1, 1, 1-10 2004/02 有 英語 研究論文(学術雑誌) 公開
K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, K Chonabayashi, H Shibasaki, S Shimohama K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, K Chonabayashi, H Shibasaki, S Shimohama K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, K Chonabayashi, H Shibasaki, S Shimohama Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane JOURNAL OF NEUROSCIENCE RESEARCH, 74, 2, 184-191 JOURNAL OF NEUROSCIENCE RESEARCH, 74, 2, 184-191 JOURNAL OF NEUROSCIENCE RESEARCH, 74, 2, 184-191 2003/10 有 英語 研究論文(学術雑誌) 公開
K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, H Shibasaki, S Shimohama K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, H Shibasaki, S Shimohama K Uemura, N Kitagawa, R Kohno, A Kuzuya, T Kageyama, H Shibasaki, S Shimohama Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling JOURNAL OF NEUROSCIENCE RESEARCH, 73, 2, 166-175 JOURNAL OF NEUROSCIENCE RESEARCH, 73, 2, 166-175 JOURNAL OF NEUROSCIENCE RESEARCH, 73, 2, 166-175 2003/07 有 英語 研究論文(学術雑誌) 公開
A Kitagawa, S Shimohama, T Oeda, K Uemura, R Kohno, A Kuzuya, H Shibasaki, N Ishii A Kitagawa, S Shimohama, T Oeda, K Uemura, R Kohno, A Kuzuya, H Shibasaki, N Ishii A Kitagawa, S Shimohama, T Oeda, K Uemura, R Kohno, A Kuzuya, H Shibasaki, N Ishii The role of the presenilin-1 homologue gene sel-12 of Caenorhabditis elegans in apoptotic activities The role of the presenilin-1 homologue gene sel-12 of Caenorhabditis elegans in apoptotic activities The role of the presenilin-1 homologue gene sel-12 of Caenorhabditis elegans in apoptotic activities JOURNAL OF BIOLOGICAL CHEMISTRY, 278, 14, 12130-12134 JOURNAL OF BIOLOGICAL CHEMISTRY, 278, 14, 12130-12134 JOURNAL OF BIOLOGICAL CHEMISTRY, 278, 14, 12130-12134 2003/04 有 英語 研究論文(学術雑誌) 公開
葛谷 聡, 矢澤 省吾, 池田 昭夫, 長峯 隆, 國枝 武治, 滝 和郎, 木村 淳, 柴崎 浩 葛谷 聡, 矢澤 省吾, 池田 昭夫, 長峯 隆, 國枝 武治, 滝 和郎, 木村 淳, 柴崎 浩 KUZUYA Akira, YAZAWA Shogo, IKEDA Akio, NAGAMINE Takashi, KUNIEDA Takeharu, TAKI Waro, KIMURA Jun, SHIBASAKI Hiroshi Jerk-locked back averaging (JLA)法によっててんかん発作時焦点が確認された補足運動野発作の一症例 Jerk-locked back averaging (JLA)法によっててんかん発作時焦点が確認された補足運動野発作の一症例 Use of jerk-locked back averaging for detecting the epileptiform discharge in a patient with supplementary motor seizure 臨床神経学, 37, 10, 923-926 臨床神経学, 37, 10, 923-926 , 37, 10, 923-926 1997/10/01 日本語 公開

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著者 著者(日本語) 著者(英語) タイトル タイトル(日本語) タイトル(英語) 書誌情報等 書誌情報等(日本語) 書誌情報等(英語) 出版年月 査読の有無 記述言語 掲載種別 公開
真田悠希, 梶川駿介, 小林勝哉, 下竹昭寛, 葛谷聡, 松本理器, 池田昭夫, 髙橋良輔 真田悠希, 梶川駿介, 小林勝哉, 下竹昭寛, 葛谷聡, 松本理器, 池田昭夫, 髙橋良輔 非けいれん性てんかん重積によりカタトニア症状を呈した一例 非けいれん性てんかん重積によりカタトニア症状を呈した一例 臨床神経学 臨床神経学 2018/03 公開
平拓実, 下竹昭寛, 井上岳司, 井上岳司, 田邊康人, 田邊康人, 粟屋智就, 加藤竹雄, 加藤竹雄, 葛谷聡, 池田昭夫, 高橋良輔 平拓実, 下竹昭寛, 井上岳司, 井上岳司, 田邊康人, 田邊康人, 粟屋智就, 加藤竹雄, 加藤竹雄, 葛谷聡, 池田昭夫, 高橋良輔 平拓実, 下竹昭寛, 井上岳司, 井上岳司, 田邊康人, 田邊康人, 粟屋智就, 加藤竹雄, 加藤竹雄, 葛谷聡, 池田昭夫, 高橋良輔 てんかん発作と発作性運動誘発性舞踏アテトーゼが併存したPRRT2遺伝子変異の一例 てんかん発作と発作性運動誘発性舞踏アテトーゼが併存したPRRT2遺伝子変異の一例 てんかん発作と発作性運動誘発性舞踏アテトーゼが併存したPRRT2遺伝子変異の一例 臨床神経学(Web), 58, 4, 274(J‐STAGE) 臨床神経学(Web), 58, 4, 274(J‐STAGE) 臨床神経学(Web), 58, 4, 274(J‐STAGE) 2018 日本語 公開
濱口敏和, 松本理器, 小林勝哉, 尾谷真弓, 本多正幸, 坂本光弘, 葛谷聡, 種田二郎, 高橋良輔, 池田昭夫 濱口敏和, 松本理器, 小林勝哉, 尾谷真弓, 本多正幸, 坂本光弘, 葛谷聡, 種田二郎, 高橋良輔, 池田昭夫 臨床発作なくsubclinical EEZ seizure patternのみを呈した自己免疫性辺縁系脳炎の2例 臨床発作なくsubclinical EEZ seizure patternのみを呈した自己免疫性辺縁系脳炎の2例 てんかん研究 てんかん研究 2017/11 公開
Masayuki Honda, Riki Matsumoto, Akihiro Shimotake, Yuichiro Hashi, Mitsuhiro Shimotake, Daiki Fujii, Katsuya Kobayashi, Akira Kuzuya, Ryosuke Takahashi, Akio Ikeda Masayuki Honda, Riki Matsumoto, Akihiro Shimotake, Yuichiro Hashi, Mitsuhiro Shimotake, Daiki Fujii, Katsuya Kobayashi, Akira Kuzuya, Ryosuke Takahashi, Akio Ikeda Chronological Change in Mesial Temporal Structures and Whole Brain Volumetry in Patients with Anti-Voltage-Gated Potassium Channel Complex Antibodies Associated Limbic Encephalitis Chronological Change in Mesial Temporal Structures and Whole Brain Volumetry in Patients with Anti-Voltage-Gated Potassium Channel Complex Antibodies Associated Limbic Encephalitis Chronological Change in Mesial Temporal Structures and Whole Brain Volumetry in Patients with Anti-Voltage-Gated Potassium Channel Complex Antibodies Associated Limbic Encephalitis てんかん研究 てんかん研究 2017/11 公開
大井由貴, 小林勝哉, 藤井大樹, 下竹昭寛, 山下博史, 葛谷聡, 松本理器, 池田昭夫, 高橋良輔 大井由貴, 小林勝哉, 藤井大樹, 下竹昭寛, 山下博史, 葛谷聡, 松本理器, 池田昭夫, 高橋良輔 皮質ミオクローヌスにペランパネルが著効したUnverricht-Lundborg病の1例 皮質ミオクローヌスにペランパネルが著効したUnverricht-Lundborg病の1例 臨床神経学 臨床神経学 2017/07 日本語 研究発表パーパー要旨(全国大会、その他学術会議) 公開
三橋賢人, 北村彰浩, 小林勝哉, 上村紀仁, 葛谷聡, 山下博史, 澤本伸克, 近藤誉之, 漆谷真, 池田昭夫, 池田昭夫, 高橋良輔 三橋賢人, 北村彰浩, 小林勝哉, 上村紀仁, 葛谷聡, 山下博史, 澤本伸克, 近藤誉之, 漆谷真, 池田昭夫, 池田昭夫, 高橋良輔 三橋賢人, 北村彰浩, 小林勝哉, 上村紀仁, 葛谷聡, 山下博史, 澤本伸克, 近藤誉之, 漆谷真, 池田昭夫, 池田昭夫, 高橋良輔 脊髄サルコイドーシスの治療に関する臨床的検討 脊髄サルコイドーシスの治療に関する臨床的検討 脊髄サルコイドーシスの治療に関する臨床的検討 日本神経学会学術大会プログラム・抄録集, 57th, Suppl., 625-S460 日本神経学会学術大会プログラム・抄録集, 57th, Suppl., 625-S460 日本神経学会学術大会プログラム・抄録集, 57th, Suppl., 625-S460 2016/12 日本語 公開
三橋賢大, 北村彰浩, 小林勝哉, 上村紀仁, 辰巳新水, 葛谷聡, 澤本伸克, 池田昭夫, 池田昭夫, 高橋良輔 三橋賢大, 北村彰浩, 小林勝哉, 上村紀仁, 辰巳新水, 葛谷聡, 澤本伸克, 池田昭夫, 池田昭夫, 高橋良輔 三橋賢大, 北村彰浩, 小林勝哉, 上村紀仁, 辰巳新水, 葛谷聡, 澤本伸克, 池田昭夫, 池田昭夫, 高橋良輔 脊髄サルコイドーシス3例の治療経験 脊髄サルコイドーシス3例の治療経験 脊髄サルコイドーシス3例の治療経験 神経治療学, 32, 5, 782-782 神経治療学, 32, 5, 782-782 神経治療学, 32, 5, 782-782 2015/09/25 日本語 公開
野田 泰葉, 久保田 正和, 葛谷 聡, 木原 武士, 木下 彩栄 野田 泰葉, 久保田 正和, 葛谷 聡, 木原 武士, 木下 彩栄 野田 泰葉, 久保田 正和, 葛谷 聡, 木原 武士, 木下 彩栄 在宅認知症患者における食習慣変化の調査 在宅認知症患者における食習慣変化の調査 在宅認知症患者における食習慣変化の調査 Dementia Japan, 29, 3, 416-416 Dementia Japan, 29, 3, 416-416 Dementia Japan, 29, 3, 416-416 2015/09/15 日本語 公開
前迫真人, 佐々木和樹, 久保田正和, 葛谷聡, 林田菜生子, 浅田めぐみ, 渡邉究, 上村麻衣子, 木原武士, 高橋良輔, 下浜俊, 植村健吾, 木下彩栄 前迫真人, 佐々木和樹, 久保田正和, 葛谷聡, 林田菜生子, 浅田めぐみ, 渡邉究, 上村麻衣子, 木原武士, 高橋良輔, 下浜俊, 植村健吾, 木下彩栄 MAESAKO MASATO, SASAKI KAZUKI, KUBOTA MASAKAZU, KUZUYA AKIRA, HAYASHIDA NAOKO, ASADA MEGUMI, WATANABE KIWAMU, UEMURA MAIKO, KIHARA TAKESHI, TAKAHASHI RYOSUKE, SHIMOHAMA SHUN, UEMURA KENGO, KINOSHITA AYAE 運動は食事制限よりも高脂肪食によるアルツハイマー病症状の悪化を改善する 運動は食事制限よりも高脂肪食によるアルツハイマー病症状の悪化を改善する 運動は食事制限よりも高脂肪食によるアルツハイマー病症状の悪化を改善する 日本分子生物学会年会プログラム・要旨集(Web), 35th, 1P-0564 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 35th, 1P-0564 (WEB ONLY) 日本分子生物学会年会プログラム・要旨集(Web), 35th, 1P-0564 (WEB ONLY) 2012 日本語 公開
植村 健吾, 浅田 めぐみ, 渡辺 究, 葛谷 聡, 下濱 俊, 高橋 良輔, 木下 彩栄 植村 健吾, 浅田 めぐみ, 渡辺 究, 葛谷 聡, 下濱 俊, 高橋 良輔, 木下 彩栄 シナプス結合は、APPダイマー化を促進し、アミロイド産生を調節する シナプス結合は、APPダイマー化を促進し、アミロイド産生を調節する 臨床神経学, 51, 12, 1324 臨床神経学, 51, 12, 1324 , 51, 12, 1324 2011/12 公開
渡邉 究, 前迫 真人, 浅田 めぐみ, 葛谷 聡, 植村 健吾, 秋山 治彦, 高橋 良輔, 木下 彩栄 渡邉 究, 前迫 真人, 浅田 めぐみ, 葛谷 聡, 植村 健吾, 秋山 治彦, 高橋 良輔, 木下 彩栄 アストロサイトのカルシニューリンを介するアルツハイマー病の病態生理の究明 アストロサイトのカルシニューリンを介するアルツハイマー病の病態生理の究明 Dementia Japan, 25, 3, 402 Dementia Japan, 25, 3, 402 , 25, 3, 402 2011/10 公開
Kiwamu Watanabe, Masato Maesako, Megumi Asada, Akira Kuzuya, Kengo Uemura, Haruhiko Akiyama, Ryosuke Takahashi, Ayae Kinoshita Kiwamu Watanabe, Masato Maesako, Megumi Asada, Akira Kuzuya, Kengo Uemura, Haruhiko Akiyama, Ryosuke Takahashi, Ayae Kinoshita Kiwamu Watanabe, Masato Maesako, Megumi Asada, Akira Kuzuya, Kengo Uemura, Haruhiko Akiyama, Ryosuke Takahashi, Ayae Kinoshita Investigating the pathology of Alzheimer's disease related to calcineurin in astrocytes Investigating the pathology of Alzheimer's disease related to calcineurin in astrocytes Investigating the pathology of Alzheimer's disease related to calcineurin in astrocytes NEUROSCIENCE RESEARCH, 71, E289-E289 NEUROSCIENCE RESEARCH, 71, E289-E289 NEUROSCIENCE RESEARCH, 71, E289-E289 2011 英語 研究発表ペーパー要旨(国際会議) 公開
武山博文, 高橋由佳子, 櫻井健世, 井内盛遠, 葛谷聡, 伊東秀文, 松本理器, 川又純, 高橋良輔, 池田宏之, 白畑充章, 宮本享 武山博文, 高橋由佳子, 櫻井健世, 井内盛遠, 葛谷聡, 伊東秀文, 松本理器, 川又純, 高橋良輔, 池田宏之, 白畑充章, 宮本享 武山博文, 高橋由佳子, 櫻井健世, 井内盛遠, 葛谷聡, 伊東秀文, 松本理器, 川又純, 高橋良輔, 池田宏之, 白畑充章, 宮本享 静脈うっ滞を呈し,ステロイドが著効したprimary angiitis of the central nervous system(PACNS)の一例 静脈うっ滞を呈し,ステロイドが著効したprimary angiitis of the central nervous system(PACNS)の一例 静脈うっ滞を呈し,ステロイドが著効したprimary angiitis of the central nervous system(PACNS)の一例 臨床神経学, 50, 7, 504 臨床神経学, 50, 7, 504 臨床神経学, 50, 7, 504 2010/07/01 日本語 公開
Megumi Asada, Kengo Uemura, Akira Kuzuya, Nao Yamada, Masato Maesako, Kiwamu Watanabe, Koichi Ando, Oksana Berezovska, Bradley T. Hyman, Ryosuke Takahashi, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Nao Yamada, Masato Maesako, Kiwamu Watanabe, Koichi Ando, Oksana Berezovska, Bradley T. Hyman, Ryosuke Takahashi, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Nao Yamada, Masato Maesako, Kiwamu Watanabe, Koichi Ando, Oksana Berezovska, Bradley T. Hyman, Ryosuke Takahashi, Ayae Kinoshita The effect of N-cadherin/Nectin-1 expression on APP cis-dimerization The effect of N-cadherin/Nectin-1 expression on APP cis-dimerization The effect of N-cadherin/Nectin-1 expression on APP cis-dimerization NEUROSCIENCE RESEARCH, 68, E189-E189 NEUROSCIENCE RESEARCH, 68, E189-E189 NEUROSCIENCE RESEARCH, 68, E189-E189 2010 英語 研究発表ペーパー要旨(国際会議) 公開
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi PaelR, a substrate of Parkin, can also be decreased by PINK1 PaelR, a substrate of Parkin, can also be decreased by PINK1 PaelR, a substrate of Parkin, can also be decreased by PINK1 NEUROSCIENCE RESEARCH, 68, E258-E258 NEUROSCIENCE RESEARCH, 68, E258-E258 NEUROSCIENCE RESEARCH, 68, E258-E258 2010 英語 研究発表ペーパー要旨(国際会議) 公開
安藤功一, 前迫真人, 浅田めぐみ, 久保田正和, 青柳信寿, 葛谷聡, 植村健吾, 川又純, 高橋良輔, 木下彩栄 安藤功一, 前迫真人, 浅田めぐみ, 久保田正和, 青柳信寿, 葛谷聡, 植村健吾, 川又純, 高橋良輔, 木下彩栄 安藤功一, 前迫真人, 浅田めぐみ, 久保田正和, 青柳信寿, 葛谷聡, 植村健吾, 川又純, 高橋良輔, 木下彩栄 アルツハイマー病におけるN‐cadherin関連蛋白質の解析 アルツハイマー病におけるN‐cadherin関連蛋白質の解析 アルツハイマー病におけるN‐cadherin関連蛋白質の解析 日本神経学会総会プログラム・抄録集, 51st, 204 日本神経学会総会プログラム・抄録集, 51st, 204 日本神経学会総会プログラム・抄録集, 51st, 204 2010 日本語 公開
川村洋介, 三浦晶子, 小嶋勝利, 本田恭子, 近藤絵里, 山田豪, 園山拓洋, 犬塚恵, 藤井寿人, 田浦大輔, 南部拓央, 西條美佐, 福永康智, 服部頼都, 葛谷聡, 横井秀基, 曽根正勝, 金本巨哲, 八十田明宏, 深津敦司, 田村尚久, 荒井宏司, 高橋良輔, 中尾一和 川村洋介, 三浦晶子, 小嶋勝利, 本田恭子, 近藤絵里, 山田豪, 園山拓洋, 犬塚恵, 藤井寿人, 田浦大輔, 南部拓央, 西條美佐, 福永康智, 服部頼都, 葛谷聡, 横井秀基, 曽根正勝, 金本巨哲, 八十田明宏, 深津敦司, 田村尚久, 荒井宏司, 高橋良輔, 中尾一和 KAWAMURA YOSUKE, MIURA AKIKO, KOJIMA KATSUTOSHI, HONDA KYOKO, KONDO ERI, YAMADA TAKESHI, SONOYAMA TAKUHIRO, INUZUKA MEGUMI, FUJII HISATO, TAURA DAISUKE, NAMBU TAKUO, SAIJO MISA, FUKUNAGA YASUTOMO, HATTORI YORITO, KUZUYA SATOSHI, YOKOI HIDEKI, SONE MASAKATSU, KANEMOTO NAOAKI, YASODA AKIHIRO, FUKATSU ATSUSHI, TAMURA NAOHISA, ARAI HIROSHI, TAKAHASHI RYOSUKE, NAKAO KAZUWA 急性リンパ性白血病に対し全脳照射20年以上経過し顕在化した下垂体前葉機能低下症の1例 急性リンパ性白血病に対し全脳照射20年以上経過し顕在化した下垂体前葉機能低下症の1例 急性リンパ性白血病に対し全脳照射20年以上経過し顕在化した下垂体前葉機能低下症の1例 月刊医学と薬学, 62, 4, 648 月刊医学と薬学, 62, 4, 648 月刊医学と薬学, 62, 4, 648 2009/10/25 日本語 公開
Koichi Ando, Masato Maesako, Megumi Asada, Masakazu Kubota, Nobuhisa Aoyagi, Akira Kuzuya, Kengo Uemura, Jun Kawamata, Ryosuke Takahashi, Ayae Kinosita Koichi Ando, Masato Maesako, Megumi Asada, Masakazu Kubota, Nobuhisa Aoyagi, Akira Kuzuya, Kengo Uemura, Jun Kawamata, Ryosuke Takahashi, Ayae Kinosita Koichi Ando, Masato Maesako, Megumi Asada, Masakazu Kubota, Nobuhisa Aoyagi, Akira Kuzuya, Kengo Uemura, Jun Kawamata, Ryosuke Takahashi, Ayae Kinosita Analysis of N-cadherin interacting proteins in Alzheimer diesase Analysis of N-cadherin interacting proteins in Alzheimer diesase Analysis of N-cadherin interacting proteins in Alzheimer diesase NEUROSCIENCE RESEARCH, 65, S115-S115 NEUROSCIENCE RESEARCH, 65, S115-S115 NEUROSCIENCE RESEARCH, 65, S115-S115 2009 英語 研究発表ペーパー要旨(国際会議) 公開
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures NEUROSCIENCE RESEARCH, 65, S118-S118 NEUROSCIENCE RESEARCH, 65, S118-S118 NEUROSCIENCE RESEARCH, 65, S118-S118 2009 英語 研究発表ペーパー要旨(国際会議) 公開
Megumi Asada, Kengo Uemura, Akira Kuzuya, Masakazu Kubota, Shun Shimohama, Ryosuke Takahashi, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Masakazu Kubota, Shun Shimohama, Ryosuke Takahashi, Ayae Kinoshita Megumi Asada, Kengo Uemura, Akira Kuzuya, Masakazu Kubota, Shun Shimohama, Ryosuke Takahashi, Ayae Kinoshita Effects of N-cadherin on APP homodimerization Effects of N-cadherin on APP homodimerization Effects of N-cadherin on APP homodimerization NEUROSCIENCE RESEARCH, 65, S115-S115 NEUROSCIENCE RESEARCH, 65, S115-S115 NEUROSCIENCE RESEARCH, 65, S115-S115 2009 英語 研究発表ペーパー要旨(国際会議) 公開
荒井宏司, 田中智洋, 丸浜伸一郎, 森潔, 藤倉純二, 冨田努, 葛谷聡, 山田豪, 藤井寿人, 中津留有子, 南部拓央, 三浦晶子, 金本巨哲, 森山賢治, 八十田明宏, 海老原健, 平田雅一, 益崎裕章, 細田公則, 高橋良輔, 中尾一和 荒井宏司, 田中智洋, 丸浜伸一郎, 森潔, 藤倉純二, 冨田努, 葛谷聡, 山田豪, 藤井寿人, 中津留有子, 南部拓央, 三浦晶子, 金本巨哲, 森山賢治, 八十田明宏, 海老原健, 平田雅一, 益崎裕章, 細田公則, 高橋良輔, 中尾一和 ARAI HIROSHI, TANAKA TOMOHIRO, MARUHAMA SHIN'ICHIRO, MORI KIYOSHI, FUJIKURA JUNJI, TOMITA TSUTOMU, KUZUYA AKIRA, YAMADA GO, FUJII TOSHIHITO, NAKATSURU YUKO, NAMBU TAKUO, MIURA MASAKO, KANAMOTO NAOAKI, MORIYAMA KENJI, YASODA AKIHIRO, EBIHARA KEN, HIRATA MASAKAZU, MASUZAKI HIROAKI, HOSODA KIMINORI, TAKAHASHI RYOSUKE, NAKAO KAZUWA 糖尿病を合併し,免疫グロブリン療法により改善をみた抗GAD抗体陽性を示した小脳失調症の1例 糖尿病を合併し,免疫グロブリン療法により改善をみた抗GAD抗体陽性を示した小脳失調症の1例 糖尿病を合併し,免疫グロブリン療法により改善をみた抗GAD抗体陽性を示した小脳失調症の1例 糖尿病, 50, 9, 703-707 糖尿病, 50, 9, 703-707 糖尿病, 50, 9, 703-707 2007/09/30 日本語 公開
田中 智洋, 荒井 宏司, 丸浜 伸一郎, 益崎 裕章, 葛谷 聡, 日下部 徹, 小林 望美, 泰江 慎太郎, 石井 崇子, 冨田 努, 藤倉 純二, 海老原 健, 平田 雅一, 細田 公則, 高橋 良輔, 中尾 一和 田中 智洋, 荒井 宏司, 丸浜 伸一郎, 益崎 裕章, 葛谷 聡, 日下部 徹, 小林 望美, 泰江 慎太郎, 石井 崇子, 冨田 努, 藤倉 純二, 海老原 健, 平田 雅一, 細田 公則, 高橋 良輔, 中尾 一和 糖尿病を契機に診断、免疫グロブリンにより改善をみた抗GAD抗体陽性小脳萎縮症の1例 糖尿病を契機に診断、免疫グロブリンにより改善をみた抗GAD抗体陽性小脳萎縮症の1例 糖尿病, 50, 6, 456-456 糖尿病, 50, 6, 456-456 , 50, 6, 456-456 2007/06 日本語 公開
Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Ayae Kinoshita, Ryousuke Takahashi Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Ayae Kinoshita, Ryousuke Takahashi Nobuhisa Aoyagi, Kengo Uemura, Akira Kuzuya, Ayae Kinoshita, Ryousuke Takahashi PI3K/AKT/GSK3 beta pathway regulates the expression of gamma secretase complex PI3K/AKT/GSK3 beta pathway regulates the expression of gamma secretase complex PI3K/AKT/GSK3 beta pathway regulates the expression of gamma secretase complex NEUROSCIENCE RESEARCH, 58, S175-S175 NEUROSCIENCE RESEARCH, 58, S175-S175 NEUROSCIENCE RESEARCH, 58, S175-S175 2007 英語 研究発表ペーパー要旨(国際会議) 公開
Kengo Uemura, Akira Kuzuya, Nobuhisa Aoyagi, Koichi Ando, Ryosuke Takahashi, Shun Shimohama, Ayae Kinoshita Kengo Uemura, Akira Kuzuya, Nobuhisa Aoyagi, Koichi Ando, Ryosuke Takahashi, Shun Shimohama, Ayae Kinoshita Kengo Uemura, Akira Kuzuya, Nobuhisa Aoyagi, Koichi Ando, Ryosuke Takahashi, Shun Shimohama, Ayae Kinoshita N-cadherin enhances extracellular secretion of A beta N-cadherin enhances extracellular secretion of A beta N-cadherin enhances extracellular secretion of A beta NEUROSCIENCE RESEARCH, 58, S117-S117 NEUROSCIENCE RESEARCH, 58, S117-S117 NEUROSCIENCE RESEARCH, 58, S117-S117 2007 英語 研究発表ペーパー要旨(国際会議) 公開
川又純, 植村健吾, 安藤功一, 青柳信寿, 葛谷聡, 辻輝之, 下濱俊, 木下彩栄, 高橋良輔 川又純, 植村健吾, 安藤功一, 青柳信寿, 葛谷聡, 辻輝之, 下濱俊, 木下彩栄, 高橋良輔 川又純, 植村健吾, 安藤功一, 青柳信寿, 葛谷聡, 辻輝之, 下濱俊, 木下彩栄, 高橋良輔 リン酸化類似変異プレセニリン1トランスジェニックマウスのプロテオーム解析 リン酸化類似変異プレセニリン1トランスジェニックマウスのプロテオーム解析 リン酸化類似変異プレセニリン1トランスジェニックマウスのプロテオーム解析 日本神経学会総会プログラム・抄録集, 48th, 237 日本神経学会総会プログラム・抄録集, 48th, 237 日本神経学会総会プログラム・抄録集, 48th, 237 2007 日本語 公開
細田公則, 田中智洋, 荒井宏司, 丸浜伸一郎, 葛谷聡, 藤井寿人, 金本巨哲, 森山賢治, 八十田明宏, 藤倉純二, 平田雅一, 海老原健, 益崎裕章, 高橋良輔, 中尾一和 細田公則, 田中智洋, 荒井宏司, 丸浜伸一郎, 葛谷聡, 藤井寿人, 金本巨哲, 森山賢治, 八十田明宏, 藤倉純二, 平田雅一, 海老原健, 益崎裕章, 高橋良輔, 中尾一和 HOSODA KIMINORI, TANAKA TOMOHIRO, ARAI KOJI, MARUHAMA SHIN'ICHIRO, KUZUYA SATOSHI, FUJII SHUJI, KANEMOTO NAOAKI, MORIYAMA KENJI, YASODA AKIHIRO, FUJIKURA JUNJI, HIRATA MASAKAZU, EBIHARA KEN, MASUZAKI HIROAKI, TAKAHASHI RYOSUKE, NAKAO KAZUWA 小脳萎縮症経過中に抗GAD抗体陽性の糖尿病を発症した一例 小脳萎縮症経過中に抗GAD抗体陽性の糖尿病を発症した一例 小脳萎縮症経過中に抗GAD抗体陽性の糖尿病を発症した一例 日本内分泌学会雑誌, 82, 3, 679 日本内分泌学会雑誌, 82, 3, 679 日本内分泌学会雑誌, 82, 3, 679 2006/12/20 日本語 公開
K Uemura, A Kuzuya, S Shimohama K Uemura, A Kuzuya, S Shimohama K Uemura, A Kuzuya, S Shimohama The cell biology of presenilin 1-mediated cleavage of N-cadherin The cell biology of presenilin 1-mediated cleavage of N-cadherin The cell biology of presenilin 1-mediated cleavage of N-cadherin NEUROBIOLOGY OF AGING, 25, S565-S565 NEUROBIOLOGY OF AGING, 25, S565-S565 NEUROBIOLOGY OF AGING, 25, S565-S565 2004/07 英語 研究発表ペーパー要旨(国際会議) 公開

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タイトル言語:
講演・口頭発表等
タイトル タイトル(日本語) タイトル(英語) 会議名 会議名(日本語) 会議名(英語) 主催者 主催者(日本語) 主催者(英語) 発表年月日 記述言語 会議種別 公開
Synaptotagmin1 is involved in modulation of amyloid beta protein production via a calcium-dependent interaction with presenilin 1. Synaptotagmin1 is involved in modulation of amyloid beta protein production via a calcium-dependent interaction with presenilin 1. Synaptotagmin1 is involved in modulation of amyloid beta protein production via a calcium-dependent interaction with presenilin 1. 第38回日本神経科学大会 第38回日本神経科学大会 2015/07 口頭発表(一般) 公開
タイトル言語:
外部資金：競争的資金 (科学研究費補助金)
種別 代表/分担 テーマ(日本語) テーマ(英語) 期間
基盤研究C 代表 シナプス小胞蛋白SV2BとBACE1の新規結合に着目したアルツハイマー病創薬研究 2020/04/01〜2022/03/31
その他の研究活動等
名称 場所 備考 期間
アルツハイマー病とてんかんを考える会 京都教育文化センター 両疾患を専門にする臨床医、研究者が集う学際研究 2015/09/14〜
部局運営（役職等）
役職名 期間
動物実験施設運営委員会 2018/04/01〜2019/03/31

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