塩川雅広

Last Update: 2019/06/27 01:09:44

Name(Kanji/Kana/Abecedarium Latinum)

塩川雅広/シオカワマサヒロ/Shiokawa, Masahiro

Primary Affiliation(Org1/Job title)

Kyoto University Hospital/Program-Specific Assistant Professor, University Hospital

Academic Degree

Field(Japanese)	Field(English)	University(Japanese)	University(English)	Method
博士（医学）	Ph.D., Medicine	京都大学	Kyoto University

Graduate School

University(Japanese)	University(English)	Faculty(Japanese)	Faculty(English)	Major(Japanese)	Major(English)	Degree
京都大学	Kyoto University	大学院医学研究科博士課程医学専攻	Graduate School of Medicine		Gastoroenterology and Hepatology	研究指導認定退学
京都大学	Kyoto University	大学院医学研究科博士課程医学専攻	Graduate School of Medicine		Gastoroenterology and Hepatology	修了

Undergraduate School / Major(s)

University(Japanese)	University(English)	Faculty(Japanese)	Faculty(English)	Major(s)(Japanese)	Major(s)(English)	Degree
京都大学	Kyoto University	医学部医学科	School of Medicine			卒業

High School

Highschool	Kana
高田高等学校	たかだこうとうがっこう

Work Experience

Period	Organization(Japanese)	Job title(Japanese)
2003/05/06-2004/05/31	京都大学医学部附属病院	初期研修医
2004/06/01-2007/03/31	公立高島総合病院	医師
2007/04/01-2010/03/31	大津日赤病院消化器内科	医師
2014/04/01-2017/03/31	京都大学医学部附属病院　消化器内科	医員
2017/04/01-2019/03/31	神戸大学大学院　医学研究科　消化器内科学	特別研究員
2019/04/01-	京都大学医学部附属病院　消化器内科	特定病院助教

Language of Instruction

Language
Japanese

researchmap URL

https://researchmap.jp/7000010374

Research Topics

(Japanese)
「IgG4関連疾患の自己抗体の同定とこれを用いた新規診断キットの開発よる新しい診療体系の確立」
(English)
Identifying autoantigens of IgG4-RD and application these antigens for dignosis

Overview of the research

(Japanese)
自己免疫性膵炎は自己免疫機序の関与が示唆されてきたが、病態形成に寄与する自己抗体が存在するのか、自己抗原は何であるのか同定されていなかった。我々の研究は、自己免疫性膵炎患者のIgGがどのような役割を担っているのかという疑問に対して、「マウスに患者のIgGを投与し、病変の発症の有無を見ればよいのではないか」と考えたのが独創的な点である。更に、このマウス膵のヒトIgGの免疫染色の結果から自己抗原候補を細胞外マトリックスに絞ることが可能であった点も大きな利点であった。本研究により自己免疫性膵炎の病態解明に加え、新たな診療体系が発信されることが期待され、国際的なインパクトも大きいものと想定される。
(English)
The pathophysiology in patients with Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) remain unknown. To reveal the pathogenicity of Immunoglobulin G (IgG) in patients with IgG4-RD, we injected their IgGs into neonatal Balb/c mice. In addition, we also examined the pathogenic activity of IgG1, IgG2, IgG3, and IgG4 in patients with IgG4-RD by injecting their IgGs into neonatal Balb/c mice. In result, subcutaneous injection of patients’ IgG, but not control IgG, induced pancreatic and salivary gland injuries. Interestingly, pancreatic injury was also induced by injecting patients’ IgG1 or IgG4, with more destructive change induced by IgG1 than by IgG4. In addition, binding of patients’ IgG to pancreatic extracellular matrix was confirmed in both the mouse model and AIP tissue samples. To reveal whether these antibodies in patients with IgG4-RD have also pathological effects to human, what is the antigen, and whether the pathophysiology in IgG4-RD is antigen-antibody disease, more studies are needed.

Fields of research (key words)

Key words(Japanese)	Key words(English)
自己免疫性膵炎	autoimmune pancreatitis
自己抗原	autoantigen

Published Papers

Author	Author(Japanese)	Author(English)	Title	Title(Japanese)	Title(English)	Bibliography	Bibliography(Japanese)	Bibliography(English)	Publication date	Refereed paper	Disclose
Nakamura T, Shiokawa M, Nakai Y.	塩川雅広	Nakamura T, Shiokawa M, Nakai Y.	Successful Hemostasis of Bleeding from Biliary Varices.	Successful Hemostasis of Bleeding from Biliary Varices.	Successful Hemostasis of Bleeding from Biliary Varices.	Clin Gastroenterol Hepatol.	Clin Gastroenterol Hepatol.	Clin Gastroenterol Hepatol.	2018/08	Refereed	Disclose to all
Notohara K, Kamisawa T, Uchida K, Zen Y, Kawano M, Kasashima S, Sato Y, Shiokawa M, Uehara T, Yoshifuji H, Hayashi H, Inoue K, Iwasaki K, Kawano H, Matsubayashi H, Moritani Y, Murakawa K, Oka Y, Tateno M, Okazaki K, Chiba T.	塩川雅広	Notohara K, Kamisawa T, Uchida K, Zen Y, Kawano M, Kasashima S, Sato Y, Shiokawa M, Uehara T, Yoshifuji H, Hayashi H, Inoue K, Iwasaki K, Kawano H, Matsubayashi H, Moritani Y, Murakawa K, Oka Y, Tateno M, Okazaki K, Chiba T.	Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey.	Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey.	Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey.	J Gastroenterol.	J Gastroenterol.	J Gastroenterol.	2018/07	Refereed	Disclose to all
Sakuma Y, Kodama Y, Eguchi T, Uza N, Tsuji Y, Shiokawa M, Maruno T, Kuriyama K, Nishikawa Y, Yamauchi Y, Tsuda M, Ueda T, Matsumori T, Morita T, Tomono T, Kakiuchi N, Mima A, Sogabe Y, Marui S, Kuwada T, Okada A, Watanabe T, Nakase H, Chiba T, Seno H.	塩川雅広	Sakuma Y, Kodama Y, Eguchi T, Uza N, Tsuji Y, Shiokawa M, Maruno T, Kuriyama K, Nishikawa Y, Yamauchi Y, Tsuda M, Ueda T, Matsumori T, Morita T, Tomono T, Kakiuchi N, Mima A, Sogabe Y, Marui S, Kuwada T, Okada A, Watanabe T, Nakase H, Chiba T, Seno H.	Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice.	Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice.	Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice.	Sci Rep.	Sci Rep.	Sci Rep.	2018/06	Refereed	Disclose to all
Matsumori T, Shiokawa M, Kodama Y.	塩川雅広	Matsumori T, Shiokawa M, Kodama Y.	Pancreatic Mass with Elevated Serum IgG4 Level.	Pancreatic Mass with Elevated Serum IgG4 Level.	Pancreatic Mass with Elevated Serum IgG4 Level.	Gastroenterology.	Gastroenterology.	Gastroenterology.	2018	Refereed	Disclose to all
Shiokawa M, Kodama Y, Sekiguchi K, Kuwada T, Tomono T, Kuriyama K, Yamazaki H, Morita T, Marui S, Sogabe Y, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Maruno T, Uza N, Tsuruyama T, Mimori T, Seno H, Chiba T.	塩川雅広	Shiokawa M, Kodama Y, Sekiguchi K, Kuwada T, Tomono T, Kuriyama K, Yamazaki H, Morita T, Marui S, Sogabe Y, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Maruno T, Uza N, Tsuruyama T, Mimori T, Seno H, Chiba T.	Laminin 511 is a Target Antigen in Autoimmune Pancreatitis.	Laminin 511 is a Target Antigen in Autoimmune Pancreatitis.	Laminin 511 is a Target Antigen in Autoimmune Pancreatitis.	Sci Transl Med	Sci Transl Med	Sci Transl Med	2018	Refereed	Disclose to all
Tsuji Y, Takahashi N, Isoda H, Koizumi K, Koyasu S, Sekimoto M, Imanaka Y, Yazumi S, Asada M, Nishikawa Y, Yamamoto H, Kikuchi O, Yoshida T, Inokuma T, Katsushima S, Esaka N, Okano A, Kawanami C, Kakiuchi N, Shiokawa M, Kodama Y, Moriyama I, Kajitani T, Kinoshita Y, Chiba T.	塩川雅広	Tsuji Y, Takahashi N, Isoda H, Koizumi K, Koyasu S, Sekimoto M, Imanaka Y, Yazumi S, Asada M, Nishikawa Y, Yamamoto H, Kikuchi O, Yoshida T, Inokuma T, Katsushima S, Esaka N, Okano A, Kawanami C, Kakiuchi N, Shiokawa M, Kodama Y, Moriyama I, Kajitani T, Kinoshita Y, Chiba T.	Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.	Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.	Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.	J Gastroenterol., 52, 10, 1147-1148	J Gastroenterol., 52, 10, 1147-1148	J Gastroenterol., 52, 10, 1147-1148	2017	Refereed	Disclose to all
Tsuji D, Ikeda M, Yamamoto K, Nakamori H, Kim YI, Kawasaki Y, Otake A, Yokoi M, Inoue K, Hirai K, Nakamichi H, Tokou U, Shiokawa M, Itoh K.	塩川雅広	Tsuji D, Ikeda M, Yamamoto K, Nakamori H, Kim YI, Kawasaki Y, Otake A, Yokoi M, Inoue K, Hirai K, Nakamichi H, Tokou U, Shiokawa M, Itoh K.	Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study.	Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study.	Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study.	Medicine, 95, 44, 51	Medicine, 95, 44, 51	Medicine, 95, 44, 51	2016/11	Refereed	Disclose to all
8. Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T.	塩川雅広	8. Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T.	Pathogenicity of Immunoglobulin G in Patients with IgG4-related Disease.	Pathogenicity of Immunoglobulin G in Patients with IgG4-related Disease.	Pathogenicity of Immunoglobulin G in Patients with IgG4-related Disease.	Gut, 65, 8, 1322-1332	Gut, 65, 8, 1322-1332	Gut, 65, 8, 1322-1332	2016	Refereed	Disclose to all
Sawai Y, Kodama Y, Shimizu T, Ota Y, Maruno T, Eso Y, Kurita A, Shiokawa M, Tsuji Y, Uza N, Matsumoto Y, Masui T, Uemoto S, Marusawa H, Chiba T.	塩川雅広	Sawai Y, Kodama Y, Shimizu T, Ota Y, Maruno T, Eso Y, Kurita A, Shiokawa M, Tsuji Y, Uza N, Matsumoto Y, Masui T, Uemoto S, Marusawa H, Chiba T.	Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.	Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.	Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.	Cancer Res., 75, 16, 3292-3301	Cancer Res., 75, 16, 3292-3301	Cancer Res., 75, 16, 3292-3301	2015	Refereed	Disclose to all
Arai Y, Yamashita K, Kuriyama K, Shiokawa M, Kodama Y, Sakurai T, Mizugishi K, Uchida K, Kadowaki N, Takaori A, Kudo M, Okazaki K, Strober W, Chiba T, Watanabe T.	塩川雅広	Arai Y, Yamashita K, Kuriyama K, Shiokawa M, Kodama Y, Sakurai T, Mizugishi K, Uchida K, Kadowaki N, Takaori A, Kudo M, Okazaki K, Strober W, Chiba T, Watanabe T.	Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis.	Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis.	Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis.	J Immunol., 195, 7, 3033-3044	J Immunol., 195, 7, 3033-3044	J Immunol., 195, 7, 3033-3044	2015	Refereed	Disclose to all
Honzawa Y, Nakase H, Shiokawa M, Yoshino T, Imaeda H, Matsuura M, Kodama Y, Ikeuchi H, Andoh A, Sakai Y, Nagata K, Chiba T.	塩川雅広	Honzawa Y, Nakase H, Shiokawa M, Yoshino T, Imaeda H, Matsuura M, Kodama Y, Ikeuchi H, Andoh A, Sakai Y, Nagata K, Chiba T.	Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.	Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.	Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.	Gut., 63, 12, 1902-1912	Gut., 63, 12, 1902-1912	Gut., 63, 12, 1902-1912	2014	Refereed	Disclose to all
Shiokawa M, Kodama Y, Yoshimura K, Kawanami C, Mimura J, Yamashita Y, Asada M, Kikuyama M, Okabe Y, Inokuma T, Ohana M, Kokuryu H, Takeda K, Tsuji Y, Minami R, Sakuma Y, Kuriyama K, Ota Y, Tanabe W, Maruno T, Kurita A, Sawai Y, Uza N, Watanabe T, Haga H, Chiba T.	塩川雅広	Shiokawa M, Kodama Y, Yoshimura K, Kawanami C, Mimura J, Yamashita Y, Asada M, Kikuyama M, Okabe Y, Inokuma T, Ohana M, Kokuryu H, Takeda K, Tsuji Y, Minami R, Sakuma Y, Kuriyama K, Ota Y, Tanabe W, Maruno T, Kurita A, Sawai Y, Uza N, Watanabe T, Haga H, Chiba T.	Risk of cancer in patients with autoimmune pancreatitis.	Risk of cancer in patients with autoimmune pancreatitis.	Risk of cancer in patients with autoimmune pancreatitis.	Am J Gastroenterol., 108, 4, 610-617	Am J Gastroenterol., 108, 4, 610-617	Am J Gastroenterol., 108, 4, 610-617	2013	Refereed	Disclose to all
Watanabe T, Yamashita K, Sakurai T, Kudo M, Shiokawa M, Uza N, Kodama Y, Uchida K, Okazaki K, Chiba T.	塩川雅広	Watanabe T, Yamashita K, Sakurai T, Kudo M, Shiokawa M, Uza N, Kodama Y, Uchida K, Okazaki K, Chiba T.	Toll-like receptor activation in basophils contributes to the development of IgG4-related disease.	Toll-like receptor activation in basophils contributes to the development of IgG4-related disease.	Toll-like receptor activation in basophils contributes to the development of IgG4-related disease.	J Gastroenterol, 48, 2, 247-253	J Gastroenterol, 48, 2, 247-253	J Gastroenterol, 48, 2, 247-253	2013	Refereed	Disclose to all
Kurita A, Kodama Y, Minami R, Sakuma Y, Kuriyama K, Tanabe W, Ota Y, Maruno T, Shiokawa M, Sawai Y, Uza N, Yazumi S, Yoshizawa A, Uemoto S, Chiba T.	塩川雅広	Kurita A, Kodama Y, Minami R, Sakuma Y, Kuriyama K, Tanabe W, Ota Y, Maruno T, Shiokawa M, Sawai Y, Uza N, Yazumi S, Yoshizawa A, Uemoto S, Chiba T.	Endoscopic stent placement above the intact sphincter of Oddi for biliary strictures after living donor liver transplantation.	Endoscopic stent placement above the intact sphincter of Oddi for biliary strictures after living donor liver transplantation.	Endoscopic stent placement above the intact sphincter of Oddi for biliary strictures after living donor liver transplantation.	J Gastroenterol., 48, 9, 1097-1104	J Gastroenterol., 48, 9, 1097-1104	J Gastroenterol., 48, 9, 1097-1104	2013	Refereed	Disclose to all
18. Hiramatsu Y, Watanabe T, Shiokawa M, Kurita A, Matsuura M, Uza N, Kodama Y, Chiba T.	塩川雅広	18. Hiramatsu Y, Watanabe T, Shiokawa M, Kurita A, Matsuura M, Uza N, Kodama Y, Chiba T.	Hemobilia: another complication associated with anti-thrombotic therapy.	Hemobilia: another complication associated with anti-thrombotic therapy.	Hemobilia: another complication associated with anti-thrombotic therapy.	Clin J Gastroenterol., 4, 1, 49-51	Clin J Gastroenterol., 4, 1, 49-51	Clin J Gastroenterol., 4, 1, 49-51	2011	Refereed	Disclose to all
Shio S, Kodama Y, Ida H, Shiokawa M, Kitamura K, Hatano E, Uemoto S, Chiba T.	塩川雅広	Shio S, Kodama Y, Ida H, Shiokawa M, Kitamura K, Hatano E, Uemoto S, Chiba T.	Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis.	Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis.	Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis.	Cancer Science, 102, 4, 776-783	Cancer Science, 102, 4, 776-783	Cancer Science, 102, 4, 776-783	2011	Refereed	Disclose to all
17. Shiokawa M, Kodama Y, Hiramatsu Y, Kurita A, Sawai Y, Uza N, Watanabe T, Chiba T.	塩川雅広	17. Shiokawa M, Kodama Y, Hiramatsu Y, Kurita A, Sawai Y, Uza N, Watanabe T, Chiba T.	Autoimmune pancreatitis exhibiting multiple mass lesions.	Autoimmune pancreatitis exhibiting multiple mass lesions.	Autoimmune pancreatitis exhibiting multiple mass lesions.	Case Rep Gastroenterol., 5, 3, 528-533	Case Rep Gastroenterol., 5, 3, 528-533	Case Rep Gastroenterol., 5, 3, 528-533	2011	Refereed	Disclose to all
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Misc

Author	Author(Japanese)	Title	Title(Japanese)	Bibliography	Bibliography(Japanese)	Bibliography(English)	Publication date	Disclose
塩川雅広，児玉裕三，妹尾浩.	塩川雅広，児玉裕三，妹尾浩.	IgG4関連疾患におけるIgGの病原性と自己抗体	IgG4関連疾患におけるIgGの病原性と自己抗体	膵臓, 33, 4, 743-751	膵臓, 33, 4, 743-751	, 33, 4, 743-751	2018	Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	悪性腫瘍発生との関連、膵癌についても	悪性腫瘍発生との関連、膵癌についても	膵臓, 30, 1, 101-106	膵臓, 30, 1, 101-106	, 30, 1, 101-106	2015	Disclose to all
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Conference Activities & Talks

Title	Title(Japanese)	Title(English)	Conference	Conference(Japanese)	Conference(English)	Date	Language	Assortment	Disclose
傍腫瘍症候群としての自己免疫性膵炎発症メカニズムの検討	傍腫瘍症候群としての自己免疫性膵炎発症メカニズムの検討		JDDW2018	JDDW2018		2018/11	Japanese		Disclose to all
自己免疫性膵炎の自己抗原同定に関する研究[Invited]	自己免疫性膵炎の自己抗原同定に関する研究 [Invited]		第27回日本シェーグレン症候群学会学術集会	第27回日本シェーグレン症候群学会学術集会		2018/09	Japanese	Oral presentation(invited, special)	Disclose to all
自己免疫性膵炎の自己抗原同定に関する研究	自己免疫性膵炎の自己抗原同定に関する研究		第104回日本消化器病学会総会	第104回日本消化器病学会総会		2018/04	Japanese		Disclose to all
Pathogenesis of autoimmune pancreatitis	Pathogenesis of autoimmune pancreatitis	Pathogenesis of autoimmune pancreatitis	IPRF 2017	IPRF 2017	IPRF 2017	2017/10	English		Disclose to all
Malignancy and autoimmune pancreatitis	Malignancy and autoimmune pancreatitis	Malignancy and autoimmune pancreatitis	IPRF 2017	IPRF 2017	IPRF 2017	2017/10	English		Disclose to all
自己免疫性膵炎の抗原同定	自己免疫性膵炎の抗原同定		第48回日本膵臓学会大会	第48回日本膵臓学会大会		2017/07	Japanese		Disclose to all
Is serum IgG in patients with AIP pathogenic ?	Is serum IgG in patients with AIP pathogenic ?	Is serum IgG in patients with AIP pathogenic ?	Third International Symposium on IgG4-RD and Fibrosis	Third International Symposium on IgG4-RD and Fibrosis	Third International Symposium on IgG4-RD and Fibrosis	2017/02	English		Disclose to all
IgG4関連疾患におけるIgGの病原性と標的抗原の解明	IgG4関連疾患におけるIgGの病原性と標的抗原の解明		第102回日本消化器病学会総会	第102回日本消化器病学会総会		2016/04	Japanese		Disclose to all
自己免疫性膵炎患者のIgGの病原性	自己免疫性膵炎患者のIgGの病原性		第51回消化器免疫病学会総会	第51回消化器免疫病学会総会		2014/07	Japanese		Disclose to all
自己免疫性膵炎確診例を用いたIgG4関連疾患包括診断基準の検討	自己免疫性膵炎確診例を用いたIgG4関連疾患包括診断基準の検討		第99回消化器病学会総会	第99回消化器病学会総会		2013/04	Japanese		Disclose to all
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Books etc

Author	Author(Japanese)	Title	Title(Japanese)	Publisher	Publisher(Japanese)	Publication date	Type	Disclose
塩川雅広，児玉裕三.	塩川雅広，児玉裕三.	希少・難治性疾患の診断と治療の最前線　IgG4関連疾患の診断と治療	希少・難治性疾患の診断と治療の最前線　IgG4関連疾患の診断と治療	Progress in Medicine	Progress in Medicine	2018	Joint Work	Disclose to all
塩川雅広	塩川雅広	IgG1	IgG1	消化器病学サイエンス	消化器病学サイエンス	2018		Disclose to all
塩川雅広，妹尾浩，千葉勉.	塩川雅広，妹尾浩，千葉勉.	IgG4関連疾患のIgGの病原性と標的抗原の同定	IgG4関連疾患のIgGの病原性と標的抗原の同定	アレルギーの臨床	アレルギーの臨床	2018	Joint Work	Disclose to all
塩川雅広，児玉裕三，妹尾浩，千葉勉.	塩川雅広，児玉裕三，妹尾浩，千葉勉.	自己免疫性膵炎の発症機序	自己免疫性膵炎の発症機序	臨床消化器内科	臨床消化器内科	2018	Joint Work	Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	【胆膵疾患診療の進歩】炎症性疾患　自己免疫性膵炎・IgG4関連疾患における病因・病態の進歩　新規標的抗原を中心に	【胆膵疾患診療の進歩】炎症性疾患　自己免疫性膵炎・IgG4関連疾患における病因・病態の進歩　新規標的抗原を中心に	医学のあゆみ	医学のあゆみ	2017	Joint Work	Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	【IgG4関連疾患:全身から肝胆膵の病態に迫る】病因・病態　IgG4抗体に病原性はあるのか?	【IgG4関連疾患:全身から肝胆膵の病態に迫る】病因・病態　IgG4抗体に病原性はあるのか?	肝・胆・膵	肝・胆・膵	2016	Joint Work	Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	IgG4関連硬化性胆管炎における胆道癌のリスク	IgG4関連硬化性胆管炎における胆道癌のリスク	『肝胆膵』，アークメディア出版	『肝胆膵』，アークメディア出版	2014		Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	自己免疫性膵炎と悪性腫瘍	自己免疫性膵炎と悪性腫瘍	『胆と膵』，医学図書出版	『胆と膵』，医学図書出版	2013	Joint Work	Disclose to all
塩川雅広，児玉裕三，千葉勉.	塩川雅広，児玉裕三，千葉勉.	IgG4関連疾患と悪性腫瘍　病因的相互関係	IgG4関連疾患と悪性腫瘍　病因的相互関係	『肝胆膵』，アークメディア出版	『肝胆膵』，アークメディア出版	2013	Joint Work	Disclose to all
塩川雅広	塩川雅広	自己免疫性膵炎と悪性腫瘍の関係	自己免疫性膵炎と悪性腫瘍の関係	『胆膵の病態生理』	『胆膵の病態生理』	2013	Single Work	Disclose to all
Title language:

Patents

Inventor(s)	Inventor(s) (Japanese)	Title	Title(Japanese)	Stage	Patent number	Date	Disclose
塩川雅広、桒田威、妹尾浩、千葉勉、児玉裕三	塩川雅広、桒田威、妹尾浩、千葉勉、児玉裕三	潰瘍性大腸炎と原発性硬化性胆管炎患者における抗原の同定と同抗原に対する自己抗体の測定	潰瘍性大腸炎と原発性硬化性胆管炎患者における抗原の同定と同抗原に対する自己抗体の測定	特許登録	特許2019－000060	2019/01/04	Disclose to all
塩川雅広、児玉裕三	塩川雅広、児玉裕三	IgG4関連疾患患者における抗原の同定と同抗原に対する自己抗体の測定	IgG4関連疾患患者における抗原の同定と同抗原に対する自己抗体の測定	特許登録	特許2016-142701	2016/07/20	Disclose to all
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Awards

Title(Japanese)	Organization name(Japanese)	Date
日本内科学会奨励賞	内科学会	2013/04/11
2016 年度医学系研究奨励賞	武田科学振興財団	2016/04/01
膵臓病研究奨励賞	日本膵臓病財団	2016/04/01
持田記念学術賞	持田記念医学薬学振興財団	2018/10/29

External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)

Type	Position	Title(Japanese)	Period
若手研究	Representative	IgG4関連疾患の抗原同定	2018/04/01-2020/03/31
基盤研究B	Assignment	指定難病「IgG4関連疾患」の自己抗原同定による病態解明と新しい診療体系の確立	2019/04/01-2022/03/31
研究活動スタート支援	Representative		2014/08/01-2016/03/31
若手研究B	Representative		2016/04/01-2018/03/31
特別研究員	Representative		2017/04/01-2019/03/31

External funds: other than those above

System	Main person	Title(Japanese)	Title(English)	Period
厚生労働科学研究費補助金	岡崎　和一	IgG4関連疾患の診断基準並びに診療指針の確立を目指す研究		2017/06/06-2020/03/31

塩川 雅広

塩川雅広