奥 公秀

Last Update: 2018/10/01 16:04:03

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Name(Kanji/Kana/Abecedarium Latinum)
奥 公秀/オク マサヒデ/Masahide Oku
Primary department(Org1/Job title)
Graduate Schools Agriculture/Assistant Professor
Faculty
Org1 Job title
農学部
Contact address
Type Address(Japanese) Address(English)
Office 〒606-8502 京都市左京区北白川追分町 京都大学大学院農学研究科 応用生命科学専攻 Div. of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-Oiwake、Sakyo, Kyoto 6068502, Japan
Affiliated academic organization(s) (Japanese)
Organization name(Japanese) Organization name(English)
日本農芸化学会 Japan Society for Bioscience, Biotechnology, and Agrochemistry
日本分子生物学会 The Molecular Biology Society of Japan
Academic degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
修士(理学) 京都大学
博士(農学) 京都大学
Graduate school
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(Japanese) Major(English) Degree
京都大学 大学院農学研究科博士後期課程応用生命科学専攻 修了
京都大学 大学院理学研究科修士課程生物科学専攻 修了
Personal Profile
(Japanese)
平成9年3月京都大学理学部卒業。平成11年同大学院理学研究科修士課程修了。平成15年同大学院農学研究科博士学位取得、修了。同年10月まで同大学農学部教務補佐員。平成17年3月まで同大学院農学研究科COE研究員。平成20年3月まで日本学術振興会特別研究員(基礎生物学研究所)。同年7月まで京都大学大学院農学研究科特定研究員(産学連携)。同7月同大学院農学研究科助教就任。現在に至る。
Personal website address
URL
http://www.seigyo.kais.kyoto-u.ac.jp/
ORCID ID
orcid.org/0000-0001-5991-6281
Research Topics
(Japanese)
真核微生物を主対象に、細胞内小器官の動態・細胞内酸化還元状態を制御する分子機構を解明すること
(English)
Elucidation of molecular mechanism underlying intra-cellular organelle turnover and redox regulation
Overview of your research
(Japanese)
真核生物における細胞内小器官の量調節には、自食作用(オートファジー)と呼ばれる分解作用が必須である。このオートファジーの分子機構を解明することで、細胞内小器官の量制御を可能にし、真核微生物細胞内での有用タンパク質・脂質の生産能向上を目指している。また、微生物タンパク質由来のセンサータンパク質を用いて、医学的にも重要な細胞内の酸化還元状態を検知する技術も開発している。
Fields of research (key words)
Key words(Japanese) Key words(English)
応用微生物学
酵母
自食作用
酸化還元状態
細胞内小器官
Fields of research (kaken code)
Kaken code
Applied microbiology
Applied molecular cell biology
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Oku M, Sakai Y Oku M, Sakai Y Oku M, Sakai Y Three Distinct Types of Microautophagy Based on Membrane Dynamics and Molecular Machineries. Three Distinct Types of Microautophagy Based on Membrane Dynamics and Molecular Machineries. Three Distinct Types of Microautophagy Based on Membrane Dynamics and Molecular Machineries. BioEssays : news and reviews in molecular, cellular and developmental biology BioEssays : news and reviews in molecular, cellular and developmental biology BioEssays : news and reviews in molecular, cellular and developmental biology 2018/04 Refereed English Research paper(scientific journal) Disclose to all
Abe M, Sawada Y, Uno S, Chigasaki S, Oku M, Sakai Y, Miyoshi H Abe M, Sawada Y, Uno S, Chigasaki S, Oku M, Sakai Y, Miyoshi H Abe M, Sawada Y, Uno S, Chigasaki S, Oku M, Sakai Y, Miyoshi H Role of Acyl Chain Composition of Phosphatidylcholine in Tafazzin-Mediated Remodeling of Cardiolipin in Liposomes. Role of Acyl Chain Composition of Phosphatidylcholine in Tafazzin-Mediated Remodeling of Cardiolipin in Liposomes. Role of Acyl Chain Composition of Phosphatidylcholine in Tafazzin-Mediated Remodeling of Cardiolipin in Liposomes. Biochemistry,56,47,6268-6280 Biochemistry,56,47,6268-6280 Biochemistry,56,47,6268-6280 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai Evidence for ESCRT- and clathrin-dependent microautophagy Evidence for ESCRT- and clathrin-dependent microautophagy Evidence for ESCRT- and clathrin-dependent microautophagy The Journal of Cell Biology,216,10,jcb.201611029-3274 The Journal of Cell Biology,216,10,jcb.201611029-3274 The Journal of Cell Biology,216,10,jcb.201611029-3274 2017/10 Refereed English Research paper(scientific journal) Disclose to all
Maeda Y, Oku M, Sakai Y Maeda Y, Oku M, Sakai Y Maeda Y, Oku M, Sakai Y Autophagy-independent function of Atg8 in lipid droplet dynamics in yeast. Autophagy-independent function of Atg8 in lipid droplet dynamics in yeast. Autophagy-independent function of Atg8 in lipid droplet dynamics in yeast. Journal of Biochemistry,161,4,339-348 Journal of Biochemistry,161,4,339-348 Journal of Biochemistry,161,4,339-348 2017/04 Refereed English Research paper(scientific journal) Disclose to all
Yamashita SI, Oku M, Sakai Y, Fujiki Y Yamashita SI, Oku M, Sakai Y, Fujiki Y Yamashita SI, Oku M, Sakai Y, Fujiki Y Experimental Systems to Study Yeast Pexophagy. Experimental Systems to Study Yeast Pexophagy. Experimental Systems to Study Yeast Pexophagy. Methods in Molecular Biology,1595,249-255 Methods in Molecular Biology,1595,249-255 Methods in Molecular Biology,1595,249-255 2017 Refereed English Research paper(scientific journal) Disclose to all
Abe M, Hasegawa Y, Oku M, Sawada Y, Tanaka E, Sakai Y, Miyoshi H Abe M, Hasegawa Y, Oku M, Sawada Y, Tanaka E, Sakai Y, Miyoshi H Abe M, Hasegawa Y, Oku M, Sawada Y, Tanaka E, Sakai Y, Miyoshi H Mechanism for Remodeling of the Acyl Chain Composition of Cardiolipin Catalyzed by Saccharomyces cerevisiae Tafazzin. Mechanism for Remodeling of the Acyl Chain Composition of Cardiolipin Catalyzed by Saccharomyces cerevisiae Tafazzin. Mechanism for Remodeling of the Acyl Chain Composition of Cardiolipin Catalyzed by Saccharomyces cerevisiae Tafazzin. The Journal of Biological Chemistry,291,30,15491-15502 The Journal of Bological Chemistry,291,30,15491-15502 The Journal of Biological Chemistry,291,30,15491-15502 2016/07 Refereed English Research paper(scientific journal) Disclose to all
Oku M, Sakai Y Oku M, Sakai Y Oku M, Sakai Y Pexophagy in yeasts. Pexophagy in yeasts. Pexophagy in yeasts. Biochimica et Biophysica Acta,1863,5,992-998 Biochimica et Biophysica Acta,1863,5,992-998 Biochimica et Biophysica Acta,1863,5,992-998 2016/05 Refereed English Research paper(scientific journal) Disclose to all
Shiraishi K, Oku M, Uchida D, Yurimoto H, Sakai Y Shiraishi K, Oku M, Uchida D, Yurimoto H, Sakai Y Shiraishi K, Oku M, Uchida D, Yurimoto H, Sakai Y Regulation of nitrate and methylamine metabolism by multiple nitrogen sources in the methylotrophic yeast Candida boidinii. Regulation of nitrate and methylamine metabolism by multiple nitrogen sources in the methylotrophic yeast Candida boidinii. Regulation of nitrate and methylamine metabolism by multiple nitrogen sources in the methylotrophic yeast Candida boidinii. FEMS yeast research,15,7,fov084 FEMS yeast research,15,7,fov084 FEMS yeast research,15,7,fov084 2015/11 Refereed English Research paper(scientific journal) Disclose to all
Shiraishi K, Oku M, Kawaguchi K, Uchida D, Yurimoto H, Sakai Y Shiraishi K, Oku M, Kawaguchi K, Uchida D, Yurimoto H, Sakai Y Shiraishi K, Oku M, Kawaguchi K, Uchida D, Yurimoto H, Sakai Y Yeast nitrogen utilization in the phyllosphere during plant lifespan under regulation of autophagy. Yeast nitrogen utilization in the phyllosphere during plant lifespan under regulation of autophagy. Yeast nitrogen utilization in the phyllosphere during plant lifespan under regulation of autophagy. Scientific Reports,5,9719 Scientific Reports,5,9719 Scientific Reports,5,9719 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Maeda Y, Oku M, Sakai Y Maeda Y, Oku M, Sakai Y Maeda Y, Oku M, Sakai Y A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis. A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis. A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis. Autophagy,11,8,1247-1258 Autophagy,11,8,1247-1258 Autophagy,11,8,1247-1258 2015 Refereed English Research paper(scientific journal) Disclose to all
奥公秀、田村直輝、阪井康能 奥公秀、田村直輝、阪井康能 メチロトロフ酵母における多様なオートファジー経路とその生理機能 メチロトロフ酵母における多様なオートファジー経路とその生理機能 化学と生物,52,12,825-829 化学と生物,52,12,825-829 ,52,12,825-829 2014/12 Japanese Research paper(scientific journal) Disclose to all
Aihara M, Jin X, Kurihara Y, Yoshida Y, Matsushima Y, Oku M, Hirota Y, Saigusa T, Aoki Y, Uchiumi T, Yamamoto T, Sakai Y, Kang D, Kanki T Aihara M, Jin X, Kurihara Y, Yoshida Y, Matsushima Y, Oku M, Hirota Y, Saigusa T, Aoki Y, Uchiumi T, Yamamoto T, Sakai Y, Kang D, Kanki T Aihara M, Jin X, Kurihara Y, Yoshida Y, Matsushima Y, Oku M, Hirota Y, Saigusa T, Aoki Y, Uchiumi T, Yamamoto T, Sakai Y, Kang D, Kanki T Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast. Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast. Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast. Journal of cell science,127,Pt 14,3184-3196 Journal of cell science,127,Pt 14,3184-3196 Journal of cell science,127,Pt 14,3184-3196 2014/07 Refereed English Research paper(scientific journal) Disclose to all
Maharjan S, Oku M, Tsuda M, Hoseki J, Sakai Y Maharjan S, Oku M, Tsuda M, Hoseki J, Sakai Y Maharjan S, Oku M, Tsuda M, Hoseki J, Sakai Y Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition. Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition. Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition. Scientific Reports,4,5896 Scientific Reports,4,5896 Scientific Reports,4,5896 2014/07 Refereed English Research paper(scientific journal) Disclose to all
N. Tamura; M. Oku; Y. Sakai N. Tamura; M. Oku; Y. Sakai N. Tamura; M. Oku; Y. Sakai Atg21 regulates pexophagy via its PI(3)P-binding activity in Pichia pastoris Atg21 regulates pexophagy via its PI(3)P-binding activity in Pichia pastoris Atg21 regulates pexophagy via its PI(3)P-binding activity in Pichia pastoris FEMS Yeast Research,14,3,435-444 FEMS Yeast Research,14,3,435-444 FEMS Yeast Research,14,3,435-444 2014/05 Refereed English Research paper(scientific journal) Disclose to all
Li C, Kita A, Hashimoto Y, Ihara M, Kato A, Ogura N, Doi A, Oku M, Itoh T, Sakai Y, Sugiura R Li C, Kita A, Hashimoto Y, Ihara M, Kato A, Ogura N, Doi A, Oku M, Itoh T, Sakai Y, Sugiura R Li C, Kita A, Hashimoto Y, Ihara M, Kato A, Ogura N, Doi A, Oku M, Itoh T, Sakai Y, Sugiura R Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling. Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling. Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling. Genes to cells,19,3,177-197 Genes to cells,19,3,177-197 Genes to cells,19,3,177-197 2014/03 Refereed English Research paper(scientific journal) Disclose to all
Tamura Naoki, Oku Masahide, Sakai Yasuyoshi Tamura Naoki, Oku Masahide, Sakai Yasuyoshi Tamura Naoki, Oku Masahide, Sakai Yasuyoshi Atg21 regulates pexophagy via its PI (3) P-binding activity in Pichia pastoris Atg21 regulates pexophagy via its PI (3) P-binding activity in Pichia pastoris Atg21 regulates pexophagy via its PI (3) P-binding activity in Pichia pastoris FEMS Yeast Research,14,3,435 FEMS Yeast Research,14,3,435 FEMS Yeast Research,14,3,435 2014 Refereed English Research paper(scientific journal) Disclose to all
Oku M, Takano Y, Sakai Y Oku M, Takano Y, Sakai Y Oku M, Takano Y, Sakai Y The emerging role of autophagy in peroxisome dynamics and lipid metabolism of phyllosphere microorganisms. The emerging role of autophagy in peroxisome dynamics and lipid metabolism of phyllosphere microorganisms. The emerging role of autophagy in peroxisome dynamics and lipid metabolism of phyllosphere microorganisms. Frontiers in Plant Science,5,81 Frontiers in Plant Science,5,81 Frontiers in Plant Science,5,81 2014 Refereed English Research paper(scientific journal) Disclose to all
Oku M, Tamura N, Sakai Y Oku M, Tamura N, Sakai Y Oku M, Tamura N, Sakai Y Atg18 lifts up from and lands on the vacuolar membrane mediated by phosphorylation of its propellers. Atg18 lifts up from and lands on the vacuolar membrane mediated by phosphorylation of its propellers. Atg18 lifts up from and lands on the vacuolar membrane mediated by phosphorylation of its propellers. Autophagy,9,12,2161-2162 Autophagy,9,12,2161-2162 Autophagy,9,12,2161-2162 2013/12 English Research paper(scientific journal) Disclose to all
N. Tamura; M. Oku; M. Ito; N.N. Noda; F. Inagaki; Y. Sakai N. Tamura; M. Oku; M. Ito; N.N. Noda; F. Inagaki; Y. Sakai N. Tamura; M. Oku; M. Ito; N.N. Noda; F. Inagaki; Y. Sakai Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositidebinding activity Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositidebinding activity Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositidebinding activity Journal of Cell Biology,202,4,685-698 Journal of Cell Biology,202,4,685-698 Journal of Cell Biology,202,4,685-698 2013/08 Refereed English Research paper(scientific journal) Disclose to all
M. Oku; J. Hoseki; Y. Ichiki; Y. Sakai M. Oku; J. Hoseki; Y. Ichiki; Y. Sakai M. Oku; J. Hoseki; Y. Ichiki; Y. Sakai A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae FEBS Letters,587,6,793-798 FEBS Letters,587,6,793-798 FEBS Letters,587,6,793-798 2013/03 Refereed English Research paper(scientific journal) Disclose to all
Jun Hoseki, Masahide Oku, Yasuyoshi Sakai 寳関淳;奥公秀;阪井康能 Jun Hoseki, Masahide Oku, Yasuyoshi Sakai Development of a novel sensor protein by applying redox-sensing machinery in yeast 酵母のレドックス認識機構を応用した新しいセンサータンパク質の開発 Development of a novel sensor protein by applying redox-sensing machinery in yeast Fragrance journal,41,2,64-69 Fragrance journal,41,2,64-69 ,41,2,64-69 2013/02 Japanese Research paper(scientific journal) Disclose to all
M. Oku; Y. Ichiki; A. Shiraishi; T. Takahara; T. Maeda; Y. Sakai M. Oku; Y. Ichiki; A. Shiraishi; T. Takahara; T. Maeda; Y. Sakai M. Oku; Y. Ichiki; A. Shiraishi; T. Takahara; T. Maeda; Y. Sakai Hyper-activation of the target of rapamycin (Tor) kinase 1 decreases intracellular glutathione content in Saccharomyces cerevisiae as revealed by LC-MS/MS analysis Hyper-activation of the target of rapamycin (Tor) kinase 1 decreases intracellular glutathione content in Saccharomyces cerevisiae as revealed by LC-MS/MS analysis Hyper-activation of the target of rapamycin (Tor) kinase 1 decreases intracellular glutathione content in Saccharomyces cerevisiae as revealed by LC-MS/MS analysis Bioscience, Biotechnology and Biochemistry,77,7,1608-1611 Bioscience, Biotechnology and Biochemistry,77,7,1608-1611 Bioscience, Biotechnology and Biochemistry,77,7,1608-1611 2013 Refereed English Research paper(scientific journal) Disclose to all
M. Oku; Y. Sakai M. Oku; Y. Sakai M. Oku; Y. Sakai Assessment of physiological redox state with novel fret protein probes Assessment of physiological redox state with novel fret protein probes Assessment of physiological redox state with novel fret protein probes Antioxidants and Redox Signaling,16,7,698-704 Antioxidants and Redox Signaling,16,7,698-704 Antioxidants and Redox Signaling,16,7,698-704 2012/04 Refereed English Research paper(scientific journal) Disclose to all
奥 公秀、阪井康能 奥 公秀、阪井康能 オートファジーによるペルオキシソームの選択的分解と生理機能 オートファジーによるペルオキシソームの選択的分解と生理機能 生体の科学, 63(5), 500-501,63,5,500-501 生体の科学, 63(5), 500-501,63,5,500-501 ,63,5,500-501 2012 Japanese Research paper(scientific journal) Disclose to all
K. Kawaguchi; H. Yurimoto; M. Oku; Y. Sakai K. Kawaguchi; H. Yurimoto; M. Oku; Y. Sakai K. Kawaguchi; H. Yurimoto; M. Oku; Y. Sakai Yeast methylotrophy and autophagy in a methanol-oscillating environment on growing Arabidopsis thaliana leaves Yeast methylotrophy and autophagy in a methanol-oscillating environment on growing Arabidopsis thaliana leaves Yeast methylotrophy and autophagy in a methanol-oscillating environment on growing Arabidopsis thaliana leaves PLoS ONE,6,9,e25257 PLoS ONE,6,9,e25257 PLoS ONE,6,9,e25257 2011/09 Refereed English Research paper(scientific journal) Disclose to all
C. Nishizaki; M. Nishikawa; T. Yata; T. Yamada; Y. Takahashi; M. Oku; H. Yurimoto; Y. Sakai; K. Nakanishi; Y. Takakura C. Nishizaki; M. Nishikawa; T. Yata; T. Yamada; Y. Takahashi; M. Oku; H. Yurimoto; Y. Sakai; K. Nakanishi; Y. Takakura C. Nishizaki; M. Nishikawa; T. Yata; T. Yamada; Y. Takahashi; M. Oku; H. Yurimoto; Y. Sakai; K. Nakanishi; Y. Takakura Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice Free Radical Biology and Medicine,51,3,773-779 Free Radical Biology and Medicine,51,3,773-779 Free Radical Biology and Medicine,51,3,773-779 2011/08 Refereed English Research paper(scientific journal) Disclose to all
H. Yurimoto; M. Oku; Y. Sakai H. Yurimoto; M. Oku; Y. Sakai H. Yurimoto; M. Oku; Y. Sakai Yeast methylotrophy: Metabolism, gene regulation and peroxisome homeostasis Yeast methylotrophy: Metabolism, gene regulation and peroxisome homeostasis Yeast methylotrophy: Metabolism, gene regulation and peroxisome homeostasis International Journal of Microbiology,2011 International Journal of Microbiology,2011 International Journal of Microbiology,2011 2011 Refereed English Research paper(scientific journal) Disclose to all
N. Tamura; M. Oku; Y. Sakai N. Tamura; M. Oku; Y. Sakai N. Tamura; M. Oku; Y. Sakai Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris Journal of Cell Science,123,23,4107-4116 Journal of Cell Science,123,23,4107-4116 Journal of Cell Science,123,23,4107-4116 2010/12 Refereed English Research paper(scientific journal) Disclose to all
T. Yano; M. Oku; N. Akeyama; A. Itoyama; H. Yurimoto; S. Kuge; Y. Fujiki; Y. Sakai T. Yano; M. Oku; N. Akeyama; A. Itoyama; H. Yurimoto; S. Kuge; Y. Fujiki; Y. Sakai T. Yano; M. Oku; N. Akeyama; A. Itoyama; H. Yurimoto; S. Kuge; Y. Fujiki; Y. Sakai A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes Molecular and Cellular Biology,30,15,3758-3766 Molecular and Cellular Biology,30,15,3758-3766 Molecular and Cellular Biology,30,15,3758-3766 2010/08 Refereed English Research paper(scientific journal) Disclose to all
M. Oku; Y. Sakai M. Oku; Y. Sakai M. Oku; Y. Sakai Peroxisomes as dynamic organelles: Autophagic degradation Peroxisomes as dynamic organelles: Autophagic degradation Peroxisomes as dynamic organelles: Autophagic degradation FEBS Journal,277,16,3289-3294 FEBS Journal,277,16,3289-3294 FEBS Journal,277,16,3289-3294 2010/08 Refereed English Research paper(scientific journal) Disclose to all
T. Yata; M. Nishikawa; C. Nishizaki; M. Oku; H. Yurimoto; Y. Sakai; Y. Takakura T. Yata; M. Nishikawa; C. Nishizaki; M. Oku; H. Yurimoto; Y. Sakai; Y. Takakura T. Yata; M. Nishikawa; C. Nishizaki; M. Oku; H. Yurimoto; Y. Sakai; Y. Takakura Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase Free Radical Biology and Medicine,47,12,1772-1778 Free Radical Biology and Medicine,47,12,1772-1778 Free Radical Biology and Medicine,47,12,1772-1778 2009/12/15 Refereed English Disclose to all
S.-I. Yamashita; H. Yurimoto; D. Murakami; M. Yoshikawa; M. Oku; Y. Sakai S.-I. Yamashita; H. Yurimoto; D. Murakami; M. Yoshikawa; M. Oku; Y. Sakai S.-I. Yamashita; H. Yurimoto; D. Murakami; M. Yoshikawa; M. Oku; Y. Sakai Lag-phase autophagy in the methylotrophic yeast Pichia pastoris Lag-phase autophagy in the methylotrophic yeast Pichia pastoris Lag-phase autophagy in the methylotrophic yeast Pichia pastoris Genes to Cells,14,7,861-870 Genes to Cells,14,7,861-870 Genes to Cells,14,7,861-870 2009/07 Refereed English Disclose to all
M. Asakura; S. Ninomiya; M. Sugimoto; M. Oku; S.-I. Yamashita; T. Okuno; Y. Sakai; Y. Takano M. Asakura; S. Ninomiya; M. Sugimoto; M. Oku; S.-I. Yamashita; T. Okuno; Y. Sakai; Y. Takano M. Asakura; S. Ninomiya; M. Sugimoto; M. Oku; S.-I. Yamashita; T. Okuno; Y. Sakai; Y. Takano Atg26-mediated pexophagy is required for host invasion by the plant pathogenic fungus colletotrichum orbiculare Atg26-mediated pexophagy is required for host invasion by the plant pathogenic fungus colletotrichum orbiculare Atg26-mediated pexophagy is required for host invasion by the plant pathogenic fungus colletotrichum orbiculare Plant Cell,21,4,1291-1304 Plant Cell,21,4,1291-1304 Plant Cell,21,4,1291-1304 2009/04 Refereed English Disclose to all
Oku Masahide, Sakai Yasuyoshi Oku Masahide, Sakai Yasuyoshi Oku Masahide, Sakai Yasuyoshi Pexophagy in Pichia pastoris Pexophagy in Pichia pastoris Pexophagy in Pichia pastoris Methods in enzymology,451,217 Methods in enzymology,451,217 Methods in enzymology,451,217 2008 Refereed Disclose to all
M. Oku; Y. Sakai M. Oku; Y. Sakai M. Oku; Y. Sakai Pexophagy in Pichia pastoris. Pexophagy in Pichia pastoris. Pexophagy in Pichia pastoris. Methods in enzymology,451,217-228 Methods in enzymology,451,217-228 Methods in enzymology,451,217-228 2008 Refereed English Disclose to all
S.-I. Yamashita; M. Oku; Y. Sakai S.-I. Yamashita; M. Oku; Y. Sakai S.-I. Yamashita; M. Oku; Y. Sakai Functions of PI4P and sterol glucoside are necessary for the synthesis of a nascent membrane structure during pexophagy Functions of PI4P and sterol glucoside are necessary for the synthesis of a nascent membrane structure during pexophagy Functions of PI4P and sterol glucoside are necessary for the synthesis of a nascent membrane structure during pexophagy Autophagy,3,1,35-37 Autophagy,3,1,35-37 Autophagy,3,1,35-37 2007 Refereed English Disclose to all
S.-I. Yamashita; M. Oku; Y. Wasada; Y. Ano; Y. Sakai S.-I. Yamashita; M. Oku; Y. Wasada; Y. Ano; Y. Sakai S.-I. Yamashita; M. Oku; Y. Wasada; Y. Ano; Y. Sakai PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy Journal of Cell Biology,173,5,709-717 Journal of Cell Biology,173,5,709-717 Journal of Cell Biology,173,5,709-717 2006 Refereed English Disclose to all
Y. Sakai; M. Oku; I.J. van der Klei; J.A.K.W. Kiel Y. Sakai; M. Oku; I.J. van der Klei; J.A.K.W. Kiel Y. Sakai; M. Oku; I.J. van der Klei; J.A.K.W. Kiel Pexophagy: Autophagic degradation of peroxisomes Pexophagy: Autophagic degradation of peroxisomes Pexophagy: Autophagic degradation of peroxisomes Biochimica et Biophysica Acta - Molecular Cell Research,1763,12,1767-1775 Biochimica et Biophysica Acta - Molecular Cell Research,1763,12,1767-1775 Biochimica et Biophysica Acta - Molecular Cell Research,1763,12,1767-1775 2006 Refereed English Disclose to all
M. Oku; T. Nishimura; T. Hattori; Y. Ano; S.-I. Yamashita; Y. Sakai M. Oku; T. Nishimura; T. Hattori; Y. Ano; S.-I. Yamashita; Y. Sakai M. Oku; T. Nishimura; T. Hattori; Y. Ano; S.-I. Yamashita; Y. Sakai Role of Vac8 in formation of the vacuolar sequestering membrane during micropexophagy Role of Vac8 in formation of the vacuolar sequestering membrane during micropexophagy Role of Vac8 in formation of the vacuolar sequestering membrane during micropexophagy Autophagy,2,4,272-279 Autophagy,2,4,272-279 Autophagy,2,4,272-279 2006 Refereed English Disclose to all
Y. Ano; T. Hattori; M. Oku; H. Mukaiyama; M. Baba; Y. Ohsumi; N. Kato; Y. Sakai Y. Ano; T. Hattori; M. Oku; H. Mukaiyama; M. Baba; Y. Ohsumi; N. Kato; Y. Sakai Y. Ano; T. Hattori; M. Oku; H. Mukaiyama; M. Baba; Y. Ohsumi; N. Kato; Y. Sakai A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate Molecular Biology of the Cell,16,2,446-457 Molecular Biology of the Cell,16,2,446-457 Molecular Biology of the Cell,16,2,446-457 2005 Refereed English Disclose to all
W.A. Dunn Jr.; J.M. Cregg; J.A. Kiel; I.J. van der Klei; M. Oku; Y. Sakai; A.A. Sibirny; O.V. Stasyk; M. Veenhuis W.A. Dunn Jr.; J.M. Cregg; J.A. Kiel; I.J. van der Klei; M. Oku; Y. Sakai; A.A. Sibirny; O.V. Stasyk; M. Veenhuis W.A. Dunn Jr.; J.M. Cregg; J.A. Kiel; I.J. van der Klei; M. Oku; Y. Sakai; A.A. Sibirny; O.V. Stasyk; M. Veenhuis Pexophagy: the selective autophagy of peroxisomes. Pexophagy: the selective autophagy of peroxisomes. Pexophagy: the selective autophagy of peroxisomes. Autophagy,1,2,75-83 Autophagy,1,2,75-83 Autophagy,1,2,75-83 2005 Refereed English Disclose to all
M. Oku; D. Warnecke; T. Noda; F. Müller; E. Heinz; H. Mukaiyama; N. Kato; Y. Sakai M. Oku; D. Warnecke; T. Noda; F. Müller; E. Heinz; H. Mukaiyama; N. Kato; Y. Sakai M. Oku; D. Warnecke; T. Noda; F. Müller; E. Heinz; H. Mukaiyama; N. Kato; Y. Sakai Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain EMBO Journal,22,13,3231-3241 EMBO Journal,22,13,3231-3241 EMBO Journal,22,13,3231-3241 2003 Refereed English Disclose to all
H. Mukaiyama; M. Oku; M. Baba; T. Samizo; A.T. Hammond; B.S. Glick; N. Kato; Y. Sakai H. Mukaiyama; M. Oku; M. Baba; T. Samizo; A.T. Hammond; B.S. Glick; N. Kato; Y. Sakai H. Mukaiyama; M. Oku; M. Baba; T. Samizo; A.T. Hammond; B.S. Glick; N. Kato; Y. Sakai Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy Genes to Cells,7,1,75-90 Genes to Cells,7,1,75-90 Genes to Cells,7,1,75-90 2002 Refereed English Disclose to all
H. Ishiwata; S.B. Sato; S. Kobayashi; M. Oku; A. Vertut-Doï; K. Miyajima H. Ishiwata; S.B. Sato; S. Kobayashi; M. Oku; A. Vertut-Doï; K. Miyajima H. Ishiwata; S.B. Sato; S. Kobayashi; M. Oku; A. Vertut-Doï; K. Miyajima Poly(ethylene glycol) derivative of cholesterol reduces binding step of liposome uptake by murine macrophage-like cell line J774 and human hepatoma cell line HepG2 Poly(ethylene glycol) derivative of cholesterol reduces binding step of liposome uptake by murine macrophage-like cell line J774 and human hepatoma cell line HepG2 Poly(ethylene glycol) derivative of cholesterol reduces binding step of liposome uptake by murine macrophage-like cell line J774 and human hepatoma cell line HepG2 Chemical and Pharmaceutical Bulletin,46,12,1907-1913 Chemical and Pharmaceutical Bulletin,46,12,1907-1913 Chemical and Pharmaceutical Bulletin,46,12,1907-1913 1998/12 Refereed English Disclose to all

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Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
The dynamics of lipid droplets at the crossroads between autophagy and lipolysis[Invited] The dynamics of lipid droplets at the crossroads between autophagy and lipolysis [Invited] The dynamics of lipid droplets at the crossroads between autophagy and lipolysis [Invited] 第91回日本生化学会大会 第91回日本生化学会大会 2018/09/25 English Symposium workshop panel(nominated) Disclose to all
脂肪滴量制御におけるオートファジーおよびESCRTタンパク質の機能[Invited] 脂肪滴量制御におけるオートファジーおよびESCRTタンパク質の機能 [Invited] 第123回 日本解剖学会総会・全国学術集会 第123回 日本解剖学会総会・全国学術集会 2018/03/30 Japanese Symposium workshop panel(nominated) Disclose to all
ミクロオートファジーの分子機構,生理機能の多様性 ミクロオートファジーの分子機構,生理機能の多様性 日本農芸化学会2018年度大会シンポジウム 日本農芸化学会2018年度大会シンポジウム 2018/03/18 Japanese Symposium workshop panel(nominated) Disclose to all
酵母脂肪滴のダイナミクスに関わるオートファジー[Invited] 酵母脂肪滴のダイナミクスに関わるオートファジー [Invited] 第8回 愛媛微生物学ネットワーク(NAME)・フォーラム 第8回 愛媛微生物学ネットワーク(NAME)・フォーラム 2017/10/28 Japanese Other Disclose to all
酵母液胞と脂肪滴との機能連関 酵母液胞と脂肪滴との機能連関 第81回酵母研究会講演会 第81回酵母研究会講演会 2016/03/14 Japanese Oral presentation(invited, special) Disclose to all
Induction of microautophagy during diauxic shift Induction of microautophagy during diauxic shift Induction of microautophagy during diauxic shift 27th International Conference on Yeast Genetics and Molecular Biology 27th International Conference on Yeast Genetics and Molecular Biology 27th International Conference on Yeast Genetics and Molecular Biology 2015/09/08 English Symposium workshop panel(public) Disclose to all
プロテアソーム機能障害による細胞内レドックス動態の可視化と解析 プロテアソーム機能障害による細胞内レドックス動態の可視化と解析 日本農芸化学会2011年度大会 日本農芸化学会2011年度大会 2011 Japanese Disclose to all
A new fluorescent probe to assess intra-cellular and intra-organellar redox states A new fluorescent probe to assess intra-cellular and intra-organellar redox states A new fluorescent probe to assess intra-cellular and intra-organellar redox states Yeast Genetics & Molecular Biology Meeting Yeast Genetics & Molecular Biology Meeting Yeast Genetics & Molecular Biology Meeting 2010/07/29 English Symposium workshop panel(public) Disclose to all
Searching for lipid-body autophagy and its physiological role in Saccharomyces cerevisiae” Searching for lipid-body autophagy and its physiological role in Saccharomyces cerevisiae” The 1st Sino-Japan Autophagy Symposium The 1st Sino-Japan Autophagy Symposium 2010 Japanese Oral presentation(invited, special) Disclose to all
出芽酵母のグリセロール培養時における脂肪滴の動態 出芽酵母のグリセロール培養時における脂肪滴の動態 酵母遺伝学フォーラム第43回研究報告会 酵母遺伝学フォーラム第43回研究報告会 2010 Japanese Disclose to all
Physiological roles of phosphoinositides and sterol glucoside in peroxisome dynamics Physiological roles of phosphoinositides and sterol glucoside in peroxisome dynamics Physiological roles of phosphoinositides and sterol glucoside in peroxisome dynamics 第27回内藤コンファレンス 第27回内藤コンファレンス 第27回内藤コンファレンス 2010 English Disclose to all
ストレス耐性に寄与するミクロオートファジーの分子機構 ストレス耐性に寄与するミクロオートファジーの分子機構 日本農芸化学会大会講演要旨集 日本農芸化学会大会講演要旨集 2009/03/05 Japanese Disclose to all
Monitoring of intracellular redox state under stress conditions by use of Redoxfluor, a FRET-based redox sensor Monitoring of intracellular redox state under stress conditions by use of Redoxfluor, a FRET-based redox sensor Monitoring of intracellular redox state under stress conditions by use of Redoxfluor, a FRET-based redox sensor 第61回日本細胞生物学会大会 第61回日本細胞生物学会大会 第61回日本細胞生物学会大会 2009 English Disclose to all
Molecular machinery required for microlipophagy in the yeast Saccharomyces cerevisiae” Molecular machinery required for microlipophagy in the yeast Saccharomyces cerevisiae” The 5th International Symposium on Autophagy The 5th International Symposium on Autophagy 2009 Japanese Disclose to all
ペキソファジーにおける PpAtg11 の役割 ペキソファジーにおける PpAtg11 の役割 日本農芸化学会2009年度大会 日本農芸化学会2009年度大会 2009 Japanese Disclose to all
ストレス条件下でのミクロオートファジーに機能する因子群の同定と解析 ストレス条件下でのミクロオートファジーに機能する因子群の同定と解析 第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 2008 Japanese Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
奥 公秀 奥 公秀 Bio Clinica オートファジーと疾患 Bio Clinica オートファジーと疾患 北隆館 北隆館 2018/07 Japanese Joint Work Disclose to all
奥 公秀 奥 公秀 オートファジー オートファジー 南山堂 南山堂 2018/01 Japanese Joint Work Disclose to all
Title language:
External funds, competitive funds and Grants-in-Aid for Scientific Research(kaken)
Type Position Title(Japanese) Title(English) Period
若手研究(B) Representative オートファジー分子を利用したC1酵母によるタンパク質・脂質生産のための基盤研究 2012-2013
若手研究(B) Representative オートファジー分子を利用したC1酵母によるタンパク質・脂質生産のための基盤研究 2012/04/-2014/03/
若手研究(B) Representative 脂質動態のオルガネラレベルでの調節機構解明とその応用 (平成26年度分) 2014/04/01-2015/03/31
若手研究(B) Representative 脂質動態のオルガネラレベルでの調節機構解明とその応用 (平成27年度分) 2015/04/01-2016/03/31
基盤研究(C) Representative オルガネラの健常性を支えるオートファジー・脂質代謝の分子機構解明 Elucidation of molecular mechanisms of autophagy and lipid metabolism supporting organellar soundness 2016/04/01-2019/03/31
基盤研究(C) Representative オルガネラの健常性を支えるオートファジー・脂質代謝の分子機構解明 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(C) Representative オルガネラの健常性を支えるオートファジー・脂質代謝の分子機構解明 (平成29年度分) 2017/04/01-2018/03/31
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
応用微生物学実験 後期 農学部 2011/04-2012/03
制御発酵学専攻実験 農学研究科 2011/04-2012/03
制御発酵学専攻演習 農学研究科 2011/04-2012/03
制御発酵学研究論 農学研究科 2011/04-2012/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2012/04-2013/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2013/04-2014/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 後期集中 農学研究科 2013/04-2014/03
制御発酵学専攻演習 Microbial Biotechnology Seminar 通年 農学研究科 2013/04-2014/03
制御発酵学専攻実験 Experimental Course of Microbial Biotechnology 通年 農学研究科 2013/04-2014/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2014/04-2015/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 前期集中 農学研究科 2014/04-2015/03
制御発酵学専攻演習 Microbial Biotechnology Seminar 通年 農学研究科 2014/04-2015/03
制御発酵学専攻実験 Experimental Course of Microbial Biotechnology 通年 農学研究科 2014/04-2015/03
制御発酵学専攻実験1 Experimental Course of Microbial Biotechnology1 通年 農学研究科 2015/04-2016/03
制御発酵学専攻実験 Experimental Course of Microbial Biotechnology 通年 農学研究科 2015/04-2016/03
制御発酵学専攻演習1 Microbial Biotechnology Seminar1 通年 農学研究科 2015/04-2016/03
制御発酵学専攻演習 Microbial Biotechnology Seminar 通年 農学研究科 2015/04-2016/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 前期集中 農学研究科 2015/04-2016/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2015/04-2016/03
制御発酵学専攻実験1 Experimental Course of Microbial Biotechnology1 通年 農学研究科 2016/04-2017/03
制御発酵学専攻実験2 Experimental Course of Microbial Biotechnology2 通年 農学研究科 2016/04-2017/03
制御発酵学専攻実験 Experimental Course of Microbial Biotechnology 通年 農学研究科 2016/04-2017/03
制御発酵学専攻演習1 Microbial Biotechnology Seminar1 通年 農学研究科 2016/04-2017/03
制御発酵学専攻演習2 Microbial Biotechnology Seminar2 通年 農学研究科 2016/04-2017/03
制御発酵学専攻演習 Microbial Biotechnology Seminar 通年 農学研究科 2016/04-2017/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 前期集中 農学研究科 2016/04-2017/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2016/04-2017/03
制御発酵学専攻実験1 Experimental Course of Microbial Biotechnology1 通年 農学研究科 2017/04-2018/03
制御発酵学専攻実験2 Experimental Course of Microbial Biotechnology2 通年 農学研究科 2017/04-2018/03
制御発酵学専攻実験 Experimental Course of Microbial Biotechnology 通年 農学研究科 2017/04-2018/03
制御発酵学専攻演習1 Microbial Biotechnology Seminar1 通年 農学研究科 2017/04-2018/03
制御発酵学専攻演習2 Microbial Biotechnology Seminar2 通年 農学研究科 2017/04-2018/03
制御発酵学専攻演習 Microbial Biotechnology Seminar 通年 農学研究科 2017/04-2018/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 前期集中 農学研究科 2017/04-2018/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2017/04-2018/03
制御発酵学専攻実験1 Experimental Course of Microbial Biotechnology1 通年 農学研究科 2018/04-2019/03
制御発酵学専攻実験2 Experimental Course of Microbial Biotechnology2 通年 農学研究科 2018/04-2019/03
制御発酵学専攻演習1 Microbial Biotechnology Seminar1 通年 農学研究科 2018/04-2019/03
制御発酵学専攻演習2 Microbial Biotechnology Seminar2 通年 農学研究科 2018/04-2019/03
制御発酵学講義 Biotechnology of molecular and cellular regulation 前期集中 農学研究科 2018/04-2019/03
応用微生物学実験 Laboratory Course in Applied Microbiology 後期 農学部 2018/04-2019/03

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Faculty management (title, position)
Title Period
放射線障害防止委員会 委員 -