伊藤 克彦

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Name(Kanji/Kana/Abecedarium Latinum)
伊藤 克彦/イトウ カツヒコ/Itoh, Katsuhiko
Primary Affiliation(Org1/Job title)
Kyoto University Hospital/Associate Professor
Faculty
Org1 Job title
医学部
E-mail Address
E-mail address
katsu ＠ virus.kyoto-u.ac.jp
katsuitoh ＠ kuhp.kyoto-u.ac.jp
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
日本血液学会
日本癌学会
日本再生医療学会
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
医学博士 京都大学
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
-
researchmap URL
https://researchmap.jp/7000008410
Research Topics
(Japanese)
HSP110 ファミリーの生体内での役割、条件付き・誘導性遺伝子発現マウスの作成
(English)
Role of Hsp110 family chaperons in vivo, Generation of a conditional- and inducible transgenic mouse
Overview of the research
(Japanese)
１。Hsp110 family に属する Apg-2 (Hspa4) の生体での役割を遺伝子ノックアウト・マウスを用いて解析する。また、その表現型をもたらす分子機序を明らかにし、治療への応用を目指す。 ２。条件付き・誘導性に遺伝子を発現する（または、ノックダウンする）マウスを作成する。また、このマウスを用いることで、致死性遺伝子などの解析を行うことで、従来のノックアウト・マウスやトランスジェニック・マウスを用いて解析が困難であった分子の生体内での役割を明らかにする。
(English)
(1) We are analyzing a role of Apg-2 (Hspa4) chaperon, belonging to Hsp110 family, in vivo. By dissecting molecular mechanisms of the given phenotypes, we would try to translate them to clinical application. (2) We are establishing a conditional- and inducible- transgenic (or gene knock-down) mouse system. We would clarify the role of genes in vivo, which have been hampered to be analyzed in vivo using conventional knock-out mice or transgenic mice because of the lethality.
Fields of research (key words)
Key words(Japanese) Key words(English)
シャペロン、熱誘導性蛋白質、遺伝子変異マウス、ゲノム編集 chaperon, heat shock protein, gene modified mouse, genome editing
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K and Fujita J Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K and Fujita J Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K and Fujita J Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal., 12, 574, 10.1126/scisignal.aao7232 Sci Signal., 12, 574, 10.1126/scisignal.aao7232 Sci Signal., 12, 574, 10.1126/scisignal.aao7232 2019/03 Refereed English Research paper(scientific journal) Disclose to all
Fujita T, Liu Y, Higashitsuji H, Itoh K, Shibasaki K, Fujita J and Nishiyama H. Fujita Takanori, Liu Yu, Higashitsuji Hiroaki, Itoh Katsuhiko, Shibasaki Koji, Fujita Jun, Nishiyama Hiroyuki Fujita T, Liu Y, Higashitsuji H, Itoh K, Shibasaki K, Fujita J and Nishiyama H. Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins. Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins. Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins. Biochem Biophys Res Commun., 495, 1, 935-940 Biochem Biophys Res Commun., 495, 1, 935-940 Biochem Biophys Res Commun., 495, 1, 935-940 2018/01/01 Refereed English Research paper(scientific journal) Disclose to all
Fujita T, Higashitsuji H, Higashitsuji H, Liu Y, Itoh K, Sakurai T, Kojima T, Kandori S, Nishiyama H, Fukumoto M, Fukumoto M, Shibasaki K and Fujita J. Fujita Takanori, Higashitsuji Hiroaki, Higashitsuji Hisako, Liu Yu, Itoh Katsuhiko, Sakurai Toshiharu, Kojima Takahiro, Kandori Shuya, Nishiyama Hiroyuki, Fukumoto Motoi, Fukumoto Manabu, Shibasaki Koji, Fujita Jun Fujita T, Higashitsuji H, Higashitsuji H, Liu Y, Itoh K, Sakurai T, Kojima T, Kandori S, Nishiyama H, Fukumoto M, Fukumoto M, Shibasaki K and Fujita J. TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM3. TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM3. TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM3. Sci Rep., 7, 2295 Sci Rep., 7, 2295 Sci Rep., 7, 2295 2017/05/23 Refereed English Research paper(scientific journal) Disclose to all
Sakurai T, Higashitsuji H, Kashida H, Watanabe T, Komeda Y, Nagai T, Hagiwara S, Kitano M, Nishida N, Abe T, Kiyonari H, Itoh K, Fujita J and Kudo M. Sakurai Toshiharu, Higashitsuji Hiroaki, Kashida Hiroshi, Watanabe Tomohiro, Komeda Yoriaki, Nagai Tomoyuki, Hagiwara Satoru, Kitano Masayuki, Nishida Naoshi, Abe Takaya, Kiyonari Hiroshi, Itoh Katsuhiko, Fujita Jun, Kudo Masatoshi Sakurai T, Higashitsuji H, Kashida H, Watanabe T, Komeda Y, Nagai T, Hagiwara S, Kitano M, Nishida N, Abe T, Kiyonari H, Itoh K, Fujita J and Kudo M. The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3. The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3. The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3. Oncotarget, 8, 15, 24762-24776 Oncotarget, 8, 15, 24762-24776 Oncotarget, 8, 15, 24762-24776 2017/04/11 Refereed English Research paper(scientific journal) Disclose to all
Jang K-J, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt ST, Igarashi K, Shimizu A and Sugai M. Jang Kyoung-Jin, Mano Hiroto, Aoki Koji, Hayashi Tatsunari, Muto Akihiko, Nambu Yukiko, Takahashi Katsu, Itoh Katsuhiko, Taketani Shigeru, Nutt Stephen L., Igarashi Kazuhiko, Shimizu Akira, Sugai Manabu Jang K-J, Mano H, Aoki K, Hayashi T, Muto A, Nambu Y, Takahashi K, Itoh K, Taketani S, Nutt ST, Igarashi K, Shimizu A and Sugai M. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nat. Commun., 6, 6750 Nat. Commun., 6, 6750 Nat. Commun., 6, 6750 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Adachi T, Sakurai T, Kashida H, Mine H, Hagiwara S, Matsui S, Yoshida K, Nishida N, Watanabe T, Itoh K, Fujita J and Kudo M. Adachi Teppei, Sakurai Toshiharu, Kashida Hiroshi, Mine Hiromasa, Hagiwara Satoru, Matsui Shigenaga, Yoshida Koji, Nishida Naoshi, Watanabe Tomohiro, Itoh Katsuhiko, Fujita Jun, Kudo Masatoshi Adachi T, Sakurai T, Kashida H, Mine H, Hagiwara S, Matsui S, Yoshida K, Nishida N, Watanabe T, Itoh K, Fujita J and Kudo M. Involvement of heat shock protein A4/Apg-2 in refractory inflammatory bowel disease. Involvement of heat shock protein A4/Apg-2 in refractory inflammatory bowel disease. Involvement of heat shock protein A4/Apg-2 in refractory inflammatory bowel disease. Inflamm. Bowel Dis., 21, 1, 31-39 Inflamm. Bowel Dis., 21, 1, 31-39 Inflamm. Bowel Dis., 21, 1, 31-39 2015/01 Refereed English Research paper(scientific journal) Disclose to all
Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I. Itoh K, Kishimoto J, Kohda D, Matozaki T and Akashi K. Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Yamauchi Takuji, Shima Takahiro, Kuriyama Takuro, Daitoku Shinya, Saito Yasuyuki, Miyamoto Toshihiro, Iwasaki Hiromi, Kitabayashi Issay, Itoh Katsuhiko, Kishimoto Junji, Kohda Daisuke, Matozaki Takashi, Akashi Koichi Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I. Itoh K, Kishimoto J, Kohda D, Matozaki T and Akashi K. The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogenic engraftment. The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogenic engraftment. The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogenic engraftment. Exp. Hematol., 42, 3, 163-171 Exp. Hematol., 42, 3, 163-171 Exp. Hematol., 42, 3, 163-171 2014/03 Refereed English Research paper(scientific journal) Disclose to all
Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Yamauchi Takuji, Kuriyama Takuro, Daitoku Shinya, Saito Yasuyuki, Itoh Katsuhiko, Kishimoto Junji, Kohda Daisuke, Matozaki Takashi, Akashi Koichi Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Yamauchi Takuji, Kuriyama Takuro, Daitoku Shinya, Saito Yasuyuki, Itoh Katsuhiko, Kishimoto Junji, Kohda Daisuke, Matozaki Takashi, Akashi Koichi Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Yamauchi Takuji, Kuriyama Takuro, Daitoku Shinya, Saito Yasuyuki, Itoh Katsuhiko, Kishimoto Junji, Kohda Daisuke, Matozaki Takashi, Akashi Koichi BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model BLOOD, 122, 21 BLOOD, 122, 21 BLOOD, 122, 21 2013/11/15 Refereed Disclose to all
Y. Liu; H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; K. Koike; K. Hirota; M. Fukumoto; J. Fujita Liu Yu, Higashitsuji Hiroaki, Higashitsuji Hisako, Itoh Katsuhiko, Sakurai Toshiharu, Koike Kazuhiko, Hirota Kiichi, Fukumoto Manabu, Fujita Jun Y. Liu; H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; K. Koike; K. Hirota; M. Fukumoto; J. Fujita Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1 Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1 Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1 Biochemical and Biophysical Research Communications, 432, 1, 22-27 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 432, 1, 22-27 Biochemical and Biophysical Research Communications, 432, 1, 22-27 2013/03/01 Refereed Disclose to all
T. Sakurai; M. Kudo; T. Watanabe; K. Itoh; H. Higashitsuji; T. Arizumi; T. Inoue; S. Hagiwara; K. Ueshima; N. Nishida; M. Fukumoto; J. Fujita Sakurai Toshiharu, Kudo Masatoshi, Watanabe Tomohiro, Itoh Katsuhiko, Higashitsuji Hiroaki, Arizumi Tadaaki, Inoue Tatsuo, Hagiwara Satoru, Ueshima Kazuomi, Nishida Naoshi, Fukumoto Manabu, Fujita Jun T. Sakurai; M. Kudo; T. Watanabe; K. Itoh; H. Higashitsuji; T. Arizumi; T. Inoue; S. Hagiwara; K. Ueshima; N. Nishida; M. Fukumoto; J. Fujita Hypothermia protects against fulminant hepatitis in mice by reducing reactive oxygen species production Hypothermia Protects against Fulminant Hepatitis in Mice by Reducing Reactive Oxygen Species Production Hypothermia protects against fulminant hepatitis in mice by reducing reactive oxygen species production Digestive Diseases, 31, 5-6, 440-446 DIGESTIVE DISEASES, 31, 5-6, 440-446 Digestive Diseases, 31, 5-6, 440-446 2013 Refereed Disclose to all
Y. Sumitomo; H. Higashitsuji; H. Higashitsuji; Y. Liu; T. Fujita; T. Sakurai; M.M. Candeias; K. Itoh; T. Chiba; J. Fujita Sumitomo Yasuhiko, Higashitsuji Hiroaki, Higashitsuji Hisako, Liu Yu, Fujita Takanori, Sakurai Toshiharu, Candeias Marco M., Itoh Katsuhiko, Chiba Tsutomu, Fujita Jun Y. Sumitomo; H. Higashitsuji; H. Higashitsuji; Y. Liu; T. Fujita; T. Sakurai; M.M. Candeias; K. Itoh; T. Chiba; J. Fujita Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells BMC Biotechnology, 12 BMC BIOTECHNOLOGY, 12 BMC Biotechnology, 12 2012/10/10 Refereed Disclose to all
Nambu Yukiko, Hayashi Tatsunari, Jang Kyoung-Jin, Aoki Koji, Mano Hiroto, Nakano Keiko, Osato Motomi, Takahashi Katsu, Itoh Katsuhiko, Teramukai Satoshi, Komori Toshihisa, Fujita Jun, Ito Yoshiaki, Shimizu Akira, Sugai Manabu Nambu, Yukiko;Hayashi, Tatsunari;Jang, Kyoung-Jin;Aoki, Koji;Mano, Hiroto;Nakano, Keiko;Osato, Motomi;Takahashi, Katsu;Itoh, Katsuhiko;Teramukai, Satoshi;Komori, Toshihisa;Fujita, Jun;Ito, Yoshiaki;Shimizu, Akira;Sugai, Manabu Nambu Yukiko, Hayashi Tatsunari, Jang Kyoung-Jin, Aoki Koji, Mano Hiroto, Nakano Keiko, Osato Motomi, Takahashi Katsu, Itoh Katsuhiko, Teramukai Satoshi, Komori Toshihisa, Fujita Jun, Ito Yoshiaki, Shimizu Akira, Sugai Manabu In situ differentiation of CD8 alpha alpha T cells from CD4 T cells in peripheral lymphoid tissues In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues. In situ differentiation of CD8 alpha alpha T cells from CD4 T cells in peripheral lymphoid tissues SCIENTIFIC REPORTS, 2, 642 Scientific reports, 2, 642 SCIENTIFIC REPORTS, 2, 642 2012/09/07 Refereed Japanese Disclose to all
T. Masuda; K. Itoh; H. Higashitsuji; H. Higashitsuji; N. Nakazawa; T. Sakurai; Y. Liu; H. Tokuchi; T. Fujita; Y. Zhao; H. Nishiyama; T. Tanaka; M. Fukumoto; M. Ikawa; M. Okabe; J. Fujita Masuda Tomoko, Itoh Katsuhiko, Higashitsuji Hiroaki, Higashitsuji Hisako, Nakazawa Noa, Sakurai Toshiharu, Liu Yu, Tokuchi Hiromu, Fujita Takanori, Zhao Yan, Nishiyama Hiroyuki, Tanaka Takashi, Fukumoto Manabu, Ikawa Masahito, Okabe Masaru, Fujita Jun T. Masuda; K. Itoh; H. Higashitsuji; H. Higashitsuji; N. Nakazawa; T. Sakurai; Y. Liu; H. Tokuchi; T. Fujita; Y. Zhao; H. Nishiyama; T. Tanaka; M. Fukumoto; M. Ikawa; M. Okabe; J. Fujita Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice Proceedings of the National Academy of Sciences of the United States of America, 109, 27, 10885-10890 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109, 27, 10885-10890 Proceedings of the National Academy of Sciences of the United States of America, 109, 27, 10885-10890 2012/07/03 Refereed Disclose to all
C.M. Schwartz; T. Tavakoli; C. Jamias; S.-S. Park; S. Maudsley; B. Martin; T.M. Phillips; P.J. Yao; K. Itoh; W. Ma; M.S. Rao; E. Arenas; M.P. Mattson Schwartz Catherine M., Tavakoli Tahereh, Jamias Charmaine, Park Sung-Soo, Maudsley Stuart, Martin Bronwen, Phillips Terry M., Yao Pamela J., Itoh Katsuhiko, Ma Wu, Rao Mahendra S., Arenas Ernest, Mattson Mark P. C.M. Schwartz; T. Tavakoli; C. Jamias; S.-S. Park; S. Maudsley; B. Martin; T.M. Phillips; P.J. Yao; K. Itoh; W. Ma; M.S. Rao; E. Arenas; M.P. Mattson Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells Stromal factors SDF1 alpha, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells Journal of Neuroscience Research, 90, 7, 1367-1381 JOURNAL OF NEUROSCIENCE RESEARCH, 90, 7, 1367-1381 Journal of Neuroscience Research, 90, 7, 1367-1381 2012/07 Refereed Disclose to all
Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Itoh Katsuhiko, Kishimoto Junji, Miyamoto Toshihiro, Matozaki Takashi, Akashi Koichi Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Itoh Katsuhiko, Kishimoto Junji, Miyamoto Toshihiro, Matozaki Takashi, Akashi Koichi Iwamoto Chika, Takenaka Katsuto, Urata Shingo, Shima Takahiro, Itoh Katsuhiko, Kishimoto Junji, Miyamoto Toshihiro, Matozaki Takashi, Akashi Koichi The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47 The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47 The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47 BLOOD, 118, 21, 1714 BLOOD, 118, 21, 1714 BLOOD, 118, 21, 1714 2011/11/18 Refereed Disclose to all
T. Sakurai; M. Kudo; K. Itoh; U. Ryu; H. Higashitsuji; J. Fujita Sakurai Toshiharu, Kudo Masatoshi, Itoh Katsuhiko, Ryu U., Higashitsuji Hiroaki, Fujita Jun T. Sakurai; M. Kudo; K. Itoh; U. Ryu; H. Higashitsuji; J. Fujita Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells Adriamycin Enhances Proteasome-Mediated Generation of the Proapoptotic Processed Form of MAGE-A4 in Hepatoma Cells Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells Oncology, 81, 30-35 ONCOLOGY, 81, 30-35 Oncology, 81, 30-35 2011 Refereed Disclose to all
T. Izumi; A. Takaori-Kondo; K. Shirakawa; H. Higashitsuji; K. Itoh; K. Io; M. Matsui; K. Iwai; H. Kondoh; T. Sato; M. Tomonaga; S. Ikeda; H. Akari; Y. Koyanagi; J. Fujita; T. Uchiyama Izumi Taisuke, Takaori-Kondo Akifumi, Shirakawa Kotaro, Higashitsuji Hiroaki, Itoh Katsuhiko, Io Katsuhiro, Matsui Masashi, Iwai Kazuhiro, Kondoh Hiroshi, Sato Toshihiro, Tomonaga Mitsunori, Ikeda Satoru, Akari Hirofumi, Koyanagi Yoshio, Fujita Jun, Uchiyama Takashi T. Izumi; A. Takaori-Kondo; K. Shirakawa; H. Higashitsuji; K. Itoh; K. Io; M. Matsui; K. Iwai; H. Kondoh; T. Sato; M. Tomonaga; S. Ikeda; H. Akari; Y. Koyanagi; J. Fujita; T. Uchiyama MDM2 is a novel E3 ligase for HIV-1 Vif MDM2 is a novel E3 ligase for HIV-1 Vif MDM2 is a novel E3 ligase for HIV-1 Vif Retrovirology, 6 RETROVIROLOGY, 6 Retrovirology, 6 2009/01/07 Refereed Disclose to all
Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T, and Fujita J. Umemura Atsushi, Itoh Yoshito, Itoh Katsuhiko, Yamaguchi Kanji, Nakajima Tomoki, Higashitsuji Hiroaki, Onoue Ritoshi, Fukumoto Manabu, Okanoue Takeshi, Fujita Jun Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T, and Fujita J. Association of gankyrin protein expression with early clinical stages and IGFBP-5 expression in human hepatocellular carcinoma. Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma Association of gankyrin protein expression with early clinical stages and IGFBP-5 expression in human hepatocellular carcinoma. Hepatology, 47: 493- 502, 2008., 47, 2, 493-502 HEPATOLOGY, 47, 2, 493-502 Hepatology, 47: 493- 502, 2008., 47, 2, 493-502 2008/02 Refereed Disclose to all
H. Higashitsuji; H. Higashitsuji; Y. Liu; T. Masuda; T. Fujita; H.I. Abdel-Aziz; S. Kongkham; S. Dawson; R. John Mayer; Y. Itoh; T. Sakurai; K. Itoh; J. Fujita Higashitsuji Hiroaki, Higashitsuji Hisako, Liu Yu, Masuda Tomoko, Fujita Takanorl, Abdel-Aziz H. Ismail, Kongkham Supranee, Dawson Simon, Mayer R. John, Itoh Yoshito, Sakurai Toshiharu, Itoh Katsuhiko, Fujita Jun H. Higashitsuji; H. Higashitsuji; Y. Liu; T. Masuda; T. Fujita; H.I. Abdel-Aziz; S. Kongkham; S. Dawson; R. John Mayer; Y. Itoh; T. Sakurai; K. Itoh; J. Fujita The oncoprotein gankyrin interacts with RelA and suppresses NF-κB activity The oncoprotein gankyrin interacts with ReIA and suppresses NF-kappa B activity The oncoprotein gankyrin interacts with RelA and suppresses NF-κB activity Biochemical and Biophysical Research Communications, 363, 3, 879-884 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 363, 3, 879-884 Biochemical and Biophysical Research Communications, 363, 3, 879-884 2007/11/23 Refereed Disclose to all
K. Yamaguchi; K. Itoh; T. Masuda; A. Umemura; C. Baum; Y. Itoh; T. Okanoue; J. Fujita Yamaguchi Kanji, Itoh Katsuhiko, Masuda Tomoko, Umemura Atsushi, Baum Christopher, Itoh Yoshito, Okanoue Takeshi, Fujita Jun K. Yamaguchi; K. Itoh; T. Masuda; A. Umemura; C. Baum; Y. Itoh; T. Okanoue; J. Fujita In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo Journal of Hepatology, 45, 5, 681-687 JOURNAL OF HEPATOLOGY, 45, 5, 681-687 Journal of Hepatology, 45, 5, 681-687 2006/11 Refereed Disclose to all
Itoh K, Tezuka H, Sakoda H, Konno M, Uchiyama T, Uchino H and Mori KJ. Itoh K, Tezuka H, Sakoda H, Konno M, Uchiyama T, Uchino H and Mori KJ. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Exp. Hematol., 17, 145-153 Exp. Hematol., 17, 145-153 Exp. Hematol., 17, 145-153 1989 Refereed English Research paper(scientific journal) Disclose to all
Lenfant M, Itoh K, Sakoda H, Scotty D, Sasaki NA, Wdzieczak-Bakala J and Mori KJ. Lenfant M, Itoh K, Sakoda H, Scotty D, Sasaki NA, Wdzieczak-Bakala J and Mori KJ. Enhancement of the adherence of hemopoietic stem cells to mouse bone marrow- derived stromal cell line MS-1T by a tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro. Enhancement of the adherence of hemopoietic stem cells to mouse bone marrow- derived stromal cell line MS-1T by a tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro. Enhancement of the adherence of hemopoietic stem cells to mouse bone marrow- derived stromal cell line MS-1T by a tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro. Exp. Hematol., 17, 898-902 Exp. Hematol., 17, 898-902 Exp. Hematol., 17, 898-902 1989 Refereed English Research paper(scientific journal) Disclose to all
Sawada H, Yamasaki Y, Izumi Y, Fujita K, Itoh K, Sakoda H, Tezuka H, Yoshida Y, Uchino H and Mori KJ. Sawada H, Yamasaki Y, Izumi Y, Fujita K, Itoh K, Sakoda H, Tezuka H, Yoshida Y, Uchino H and Mori KJ. IL-3 producing T cell lines derived from mouse with granulocytosis and characteristics of the colony stimulating activities. IL-3 producing T cell lines derived from mouse with granulocytosis and characteristics of the colony stimulating activities. IL-3 producing T cell lines derived from mouse with granulocytosis and characteristics of the colony stimulating activities. Acta Hematol. Jpn., 51, 816-820 Acta Hematol. Jpn., 51, 816-820 Acta Hematol. Jpn., 51, 816-820 1988 Refereed English Research paper(scientific journal) Disclose to all
Itoh K, Ono K, Sawada H, Tezuka H, Sakoda H, Nakane H, Uchiyama T, Uchino H and Mori KJ. Itoh K, Ono K, Sawada H, Tezuka H, Sakoda H, Nakane H, Uchiyama T, Uchino H and Mori KJ. Establishment of a transplantable erythroblastic leukemia in C3H mice. Establishment of a transplantable erythroblastic leukemia in C3H mice. Establishment of a transplantable erythroblastic leukemia in C3H mice. Leukemia Res., 12, 471, 478 Leukemia Res., 12, 471, 478 Leukemia Res., 12, 471, 478 1988 Refereed English Research paper(scientific journal) Disclose to all
Itoh K, Sasaki R, Ono K, Tezuka H, Sakoda H, Nakane H, Uchiyama T, Uchino H and Mori KJ. Itoh K, Sasaki R, Ono K, Tezuka H, Sakoda H, Nakane H, Uchiyama T, Uchino H and Mori KJ. Stromal cell-dependent growth of leukemic cells from murine erythroblastic leukemia. Stromal cell-dependent growth of leukemic cells from murine erythroblastic leukemia. Stromal cell-dependent growth of leukemic cells from murine erythroblastic leukemia. Jpn. J. Cancer Res., 79, 931-937 Jpn. J. Cancer Res., 79, 931-937 Jpn. J. Cancer Res., 79, 931-937 1988 Refereed English Research paper(scientific journal) Disclose to all
Sawada H, Itoh K, Sakoda H, Tezuka H, Kuribayashi K, Maeda M, Yoshida Y, Uchino H, Hanaoka M and Mori KJ. Sawada H, Itoh K, Sakoda H, Tezuka H, Kuribayashi K, Maeda M, Yoshida Y, Uchino H, Hanaoka M and Mori KJ. Establishmant of hemopoietic stimulating factor producing murine leukemia cell line:Pathogenesis of granulocytosis in L8313 bearing mice. Establishmant of hemopoietic stimulating factor producing murine leukemia cell line:Pathogenesis of granulocytosis in L8313 bearing mice. Establishmant of hemopoietic stimulating factor producing murine leukemia cell line:Pathogenesis of granulocytosis in L8313 bearing mice. Leukemia Res., 12, 763-771 Leukemia Res., 12, 763-771 Leukemia Res., 12, 763-771 1988 Refereed English Research paper(scientific journal) Disclose to all
Sakoda H, Tsurusawa M, Tezuka H, Itoh K, Ohmori S, Yoshida Y, Uchino H and Mori KJ. Sakoda H, Tsurusawa M, Tezuka H, Itoh K, Ohmori S, Yoshida Y, Uchino H and Mori KJ. Clonal assay of mast cell progenitors in semi-solid culture with a high seeding effeciency. Clonal assay of mast cell progenitors in semi-solid culture with a high seeding effeciency. Clonal assay of mast cell progenitors in semi-solid culture with a high seeding effeciency. Biomed. & Pharmacother., 42, 335-341 Biomed. & Pharmacother., 42, 335-341 Biomed. & Pharmacother., 42, 335-341 1988 Refereed English Research paper(scientific journal) Disclose to all
Sakoda H, Tsurusawa M, Tezuka H, Itoh K, Ohmori S, Yoshida Y, Uchino H and Mori KJ. Sakoda H, Tsurusawa M, Tezuka H, Itoh K, Ohmori S, Yoshida Y, Uchino H and Mori KJ. Competitive induction of erythroid progenitors by relative concentration of BPA to erythropoietin: Possible existence of intermediate compartment between BFU-E and CFU-E. Competitive induction of erythroid progenitors by relative concentration of BPA to erythropoietin: Possible existence of intermediate compartment between BFU-E and CFU-E. Competitive induction of erythroid progenitors by relative concentration of BPA to erythropoietin: Possible existence of intermediate compartment between BFU-E and CFU-E. Biomed. & Pharmacother., 42, 455-460 Biomed. & Pharmacother., 42, 455-460 Biomed. & Pharmacother., 42, 455-460 1988 Refereed English Research paper(scientific journal) Disclose to all
Tezuka H, Sawada H, Sakoda H, Itoh K, Nishikori M, Amagai T, Uchino H and Mori KJ. Tezuka H, Sawada H, Sakoda H, Itoh K, Nishikori M, Amagai T, Uchino H and Mori KJ. Supression of genetic resistance to bone marrow grafts and natural killer activity by administration of fat emalsion. Supression of genetic resistance to bone marrow grafts and natural killer activity by administration of fat emalsion. Supression of genetic resistance to bone marrow grafts and natural killer activity by administration of fat emalsion. Exp. Hematol., 16, 609-612 Exp. Hematol., 16, 609-612 Exp. Hematol., 16, 609-612 1988 Refereed English Research paper(scientific journal) Disclose to all
R. Fukuda; K. Tsuchiya; K. Suzuki; K. Itoh; J. Fujita; A. Utsunomiya; T. Tsuji R. Fukuda; K. Tsuchiya; K. Suzuki; K. Itoh; J. Fujita; A. Utsunomiya; T. Tsuji HTLV-I tax regulates the cellular proliferation through the down-regulation of PIP3-phosphatase expressions via the NF-κB pathway HTLV-I tax regulates the cellular proliferation through the down-regulation of PIP3-phosphatase expressions via the NF-κB pathway International Journal of Biochemistry and Molecular Biology, 3, 1, 95-104 , 3, 1, 95-104 International Journal of Biochemistry and Molecular Biology, 3, 1, 95-104 2012 Refereed English Disclose to all
R.-I. Fukuda; K. Tsuchiya; K. Suzuki; K. Itoh; J. Fujita; A. Utsunomiya; T. Tsuji R.-I. Fukuda; K. Tsuchiya; K. Suzuki; K. Itoh; J. Fujita; A. Utsunomiya; T. Tsuji Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-κB pathway (Journal of Biological Chemistry (2009) 284, (2680-2689)) Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-κB pathway (Journal of Biological Chemistry (2009) 284, (2680-2689)) Journal of Biological Chemistry, 286, 49, 42785- , 286, 49, 42785- Journal of Biological Chemistry, 286, 49, 42785- 2011 Refereed English Disclose to all
C. Stocking; M. Grez; B. Fehse; D. von Laer; K. Itoh; V. Prassolov; J. Nowock; K. Kühlcke; U. Just; T. Schröder; H. Klump; B. Schiedlmeier; E. Grassman; J. Meyer; Z. Li; A. Schambach; U. Modlich; O. Kustikova; M. Galla; J. Bode; A. Zander; C. Baum C. Stocking; M. Grez; B. Fehse; D. von Laer; K. Itoh; V. Prassolov; J. Nowock; K. Kühlcke; U. Just; T. Schröder; H. Klump; B. Schiedlmeier; E. Grassman; J. Meyer; Z. Li; A. Schambach; U. Modlich; O. Kustikova; M. Galla; J. Bode; A. Zander; C. Baum Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010). Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010). Human gene therapy, 21, 11, 1501-1503 , 21, 11, 1501-1503 Human gene therapy, 21, 11, 1501-1503 2010 Refereed English Disclose to all
H. Higashitsuji; H. Higashitsuji; T. Masuda; Y. Liu; K. Itoh; J. Fujita H. Higashitsuji; H. Higashitsuji; T. Masuda; Y. Liu; K. Itoh; J. Fujita Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1 Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1 Journal of Biological Chemistry, 282, 18, 13716-13725 , 282, 18, 13716-13725 Journal of Biological Chemistry, 282, 18, 13716-13725 2007/05/04 Refereed English Disclose to all
C. Heberlein; J. Friel; K. Itoh; E. Medlock; L. Li; N. Nakayama; C. Stocking; M. Geldmacher; W. Ostertag C. Heberlein; J. Friel; K. Itoh; E. Medlock; L. Li; N. Nakayama; C. Stocking; M. Geldmacher; W. Ostertag Involvement of CSF-1 in generating a stroma-independent hematopoietic stem cell line Involvement of CSF-1 in generating a stroma-independent hematopoietic stem cell line Journal of Cellular Physiology, 206, 2, 556-562 , 206, 2, 556-562 Journal of Cellular Physiology, 206, 2, 556-562 2006 Refereed English Disclose to all
T. Sakurai; K. Itoh; H. Higashitsuji; K. Nonoguchi; Y. Liu; H. Watanabe; T. Nakano; M. Fukumoto; T. Chiba; J. Fujita T. Sakurai; K. Itoh; H. Higashitsuji; K. Nonoguchi; Y. Liu; H. Watanabe; T. Nakano; M. Fukumoto; T. Chiba; J. Fujita Cirp protects against tumor necrosis factor-α-induced apoptosis via activation of extracellular signal-regulated kinase Cirp protects against tumor necrosis factor-α-induced apoptosis via activation of extracellular signal-regulated kinase Biochimica et Biophysica Acta - Molecular Cell Research, 1763, 3, 290-295 , 1763, 3, 290-295 Biochimica et Biophysica Acta - Molecular Cell Research, 1763, 3, 290-295 2006 Refereed English Disclose to all
T. Sakurai; K. Itoh; Y. Liu; H. Higashitsuji; Y. Sumitomo; K. Sakamaki; J. Fujita T. Sakurai; K. Itoh; Y. Liu; H. Higashitsuji; Y. Sumitomo; K. Sakamaki; J. Fujita Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro Experimental Cell Research, 309, 2, 264-272 , 309, 2, 264-272 Experimental Cell Research, 309, 2, 264-272 2005/10/01 Refereed English Disclose to all
H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; T. Nagao; H. Sumitomo; T. Masuda; S. Dawson; Y. Shimada; R.J. Mayer; J. Fujita H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; T. Nagao; H. Sumitomo; T. Masuda; S. Dawson; Y. Shimada; R.J. Mayer; J. Fujita The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 Cancer Cell, 8, 1, 75-87 , 8, 1, 75-87 Cancer Cell, 8, 1, 75-87 2005/07 Refereed English Disclose to all
H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; T. Nagao; Y. Sumitomo; T. Masuda; S. Dawson; Y. Shimada; R.J. Mayer; J. Fujita H. Higashitsuji; H. Higashitsuji; K. Itoh; T. Sakurai; T. Nagao; Y. Sumitomo; T. Masuda; S. Dawson; Y. Shimada; R.J. Mayer; J. Fujita Erratum: The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 (Cancer Cell 8 (75-86)) Erratum: The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 (Cancer Cell 8 (75-86)) Cancer Cell, 8, 2, 169- , 8, 2, 169- Cancer Cell, 8, 2, 169- 2005 Refereed English Disclose to all
H. Watanabe; K. Nonoguchi; T. Sakurai; T. Masuda; K. Itoh; J. Fujita H. Watanabe; K. Nonoguchi; T. Sakurai; T. Masuda; K. Itoh; J. Fujita A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor Molecular Human Reproduction, 11, 7, 471-476 , 11, 7, 471-476 Molecular Human Reproduction, 11, 7, 471-476 2005 Refereed English Disclose to all
R.-I. Fukuda; A. Hayashi; A. Utsunomiya; Y. Nukada; R. Fukui; K. Itoh; K. Tezuka; K. Ohashi; K. Mizuno; M. Sakamoto; M. Hamanoue; T. Tsuji R.-I. Fukuda; A. Hayashi; A. Utsunomiya; Y. Nukada; R. Fukui; K. Itoh; K. Tezuka; K. Ohashi; K. Mizuno; M. Sakamoto; M. Hamanoue; T. Tsuji Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL) Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL) Proceedings of the National Academy of Sciences of the United States of America, 102, 42, 15213-15218 , 102, 42, 15213-15218 Proceedings of the National Academy of Sciences of the United States of America, 102, 42, 15213-15218 2005 Refereed English Disclose to all
T. Sakurai; K. Itoh; H. Higashitsuji; T. Nagao; K. Nonoguchi; T. Chiba; J. Fujita T. Sakurai; K. Itoh; H. Higashitsuji; T. Nagao; K. Nonoguchi; T. Chiba; J. Fujita A Cleaved Form of MAGE-A4 Binds to Miz-1 and Induces Apoptosis in Human Cells A Cleaved Form of MAGE-A4 Binds to Miz-1 and Induces Apoptosis in Human Cells Journal of Biological Chemistry, 279, 15, 15505-15514 , 279, 15, 15505-15514 Journal of Biological Chemistry, 279, 15, 15505-15514 2004/04/09 Refereed English Disclose to all
K. Gotoh; K. Nonoguchi; H. Higashitsuji; Y. Kaneko; T. Sakurai; Y. Sumitomo; K. Itoh; J.R. Subjeck; J. Fujita K. Gotoh; K. Nonoguchi; H. Higashitsuji; Y. Kaneko; T. Sakurai; Y. Sumitomo; K. Itoh; J.R. Subjeck; J. Fujita Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas FEBS Letters, 560, 1-3, 19-24 , 560, 1-3, 19-24 FEBS Letters, 560, 1-3, 19-24 2004/02/27 Refereed English Disclose to all
S. Konakahara; K. Ohashi; K. Mizuno; K. Itoh; T. Tsuji S. Konakahara; K. Ohashi; K. Mizuno; K. Itoh; T. Tsuji CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells Genes to Cells, 9, 4, 345-358 , 9, 4, 345-358 Genes to Cells, 9, 4, 345-358 2004 Refereed English Disclose to all
T. Nagao; H. Higashitsuji; K. Nonoguchi; T. Sakurai; S. Dawson; R.J. Mayer; K. Itoh; J. Fujita T. Nagao; H. Higashitsuji; K. Nonoguchi; T. Sakurai; S. Dawson; R.J. Mayer; K. Itoh; J. Fujita MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity Journal of Biological Chemistry, 278, 12, 10668-10674 , 278, 12, 10668-10674 Journal of Biological Chemistry, 278, 12, 10668-10674 2003/03/21 Refereed English Disclose to all
K. Yamaguchi; K. Itoh; N. Ohnishi; Y. Itoh; C. Baum; T. Tsuji; T. Nagao; H. Higashitsuji; T. Okanoue; J. Fujita K. Yamaguchi; K. Itoh; N. Ohnishi; Y. Itoh; C. Baum; T. Tsuji; T. Nagao; H. Higashitsuji; T. Okanoue; J. Fujita Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo Molecular Therapy, 8, 5, 796-803 , 8, 5, 796-803 Molecular Therapy, 8, 5, 796-803 2003 Refereed English Disclose to all
T. Higuchi; H. Fujiwara; H. Egawa; Y. Sato; S. Yoshioka; K. Tatsumi; K. Itoh; M. Maeda; J. Fujita; S. Fujii T. Higuchi; H. Fujiwara; H. Egawa; Y. Sato; S. Yoshioka; K. Tatsumi; K. Itoh; M. Maeda; J. Fujita; S. Fujii Cyclic AMP enhances the expression of an estravillous trophoblast marker, melanoma cell adhesion molecule, in choriocarcinoma cell JEG3 and human chorionic villous explant cultures Cyclic AMP enhances the expression of an estravillous trophoblast marker, melanoma cell adhesion molecule, in choriocarcinoma cell JEG3 and human chorionic villous explant cultures Molecular Human Reproduction, 9, 5-6, 359-366 , 9, 5-6, 359-366 Molecular Human Reproduction, 9, 5-6, 359-366 2003 Refereed English Disclose to all
H. Higashitsuji; H. Higashitsuji; T. Nagao; K. Nonoguchi; S. Fujii; K. Itoh; J. Fujita H. Higashitsuji; H. Higashitsuji; T. Nagao; K. Nonoguchi; S. Fujii; K. Itoh; J. Fujita A novel protein overexpressed in hepatoma accelerates export of NF-κB from the nucleus and inhibits p53-dependent apoptosis A novel protein overexpressed in hepatoma accelerates export of NF-κB from the nucleus and inhibits p53-dependent apoptosis Cancer Cell, 2, 4, 335-346 , 2, 4, 335-346 Cancer Cell, 2, 4, 335-346 2002/10 Refereed English Disclose to all
N. Ohnishi; K. Itoh; Y. Itoh; C. Baum; H. Higashitsuji; K. Yamaguchi; T. Tsuji; T. Okanoue; J. Fujita N. Ohnishi; K. Itoh; Y. Itoh; C. Baum; H. Higashitsuji; K. Yamaguchi; T. Tsuji; T. Okanoue; J. Fujita High expression of transgenes mediated by hybrid retroviral vectors in hepatocytes: Comparison of promoters from murine retroviruses in vitro and in vivo High expression of transgenes mediated by hybrid retroviral vectors in hepatocytes: Comparison of promoters from murine retroviruses in vitro and in vivo Gene Therapy, 9, 4, 303-306 , 9, 4, 303-306 Gene Therapy, 9, 4, 303-306 2002 Refereed English Disclose to all
J. Friel; K. Itoh; U. Bergholz; M. Jücker; C. Stocking; P. Harrison; W. Ostertag J. Friel; K. Itoh; U. Bergholz; M. Jücker; C. Stocking; P. Harrison; W. Ostertag Hierarchy of stroma-derived factors in supporting growth of stroma-dependent hemopoietic cells: Membrane-bound SCF is sufficient to confer stroma competence to epithelial cells Hierarchy of stroma-derived factors in supporting growth of stroma-dependent hemopoietic cells: Membrane-bound SCF is sufficient to confer stroma competence to epithelial cells Growth Factors, 20, 1, 35-51 , 20, 1, 35-51 Growth Factors, 20, 1, 35-51 2002 Refereed English Disclose to all
A. Wahlers; O. Kustikova; P.F. Zipfel; K. Itoh; M. Koester; C. Heberlein; Z. Li; B. Schiedlmeier; C. Skerka; B. Fehse; C. Baum A. Wahlers; O. Kustikova; P.F. Zipfel; K. Itoh; M. Koester; C. Heberlein; Z. Li; B. Schiedlmeier; C. Skerka; B. Fehse; C. Baum Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells Molecular Therapy, 6, 3, 313-320 , 6, 3, 313-320 Molecular Therapy, 6, 3, 313-320 2002 Refereed English Disclose to all
A. Wahlers; O. Kustikova; P.F. Zipfel; K. Itoh; M. Koester; C. Heberlain; Z. Li; B. Schiedlmeier; C. Skerka; B. Fehse; C. Baum; M.T. Vlachaki; A. Hernandez-Garcia; M. Ittmann; M. Chhikara; L.K. Aguilar; X. Zhu; B.S. Teh; E.B. Butler; S. Woo; T.C. Thompson; H. Barrera-Saldana; E. Aguilar-Cordova A. Wahlers; O. Kustikova; P.F. Zipfel; K. Itoh; M. Koester; C. Heberlain; Z. Li; B. Schiedlmeier; C. Skerka; B. Fehse; C. Baum; M.T. Vlachaki; A. Hernandez-Garcia; M. Ittmann; M. Chhikara; L.K. Aguilar; X. Zhu; B.S. Teh; E.B. Butler; S. Woo; T.C. Thompson; H. Barrera-Saldana; E. Aguilar-Cordova Erratum: Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells (Molecular Therapy (2002) vol. 6 (313-320)) Erratum: Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells (Molecular Therapy (2002) vol. 6 (313-320)) Molecular Therapy, 6, 4, 563- , 6, 4, 563- Molecular Therapy, 6, 4, 563- 2002 Refereed English Disclose to all
Y. Hirose; H. Kiyoi; K. Itoh; K. Kato; H. Saito; T. Naoe Y. Hirose; H. Kiyoi; K. Itoh; K. Kato; H. Saito; T. Naoe B-cell precursors differentiated from cord blood CD34<sup>+</sup> cells are more immature than those derived from granulocyte colony-stimulating factor-mobilized peripheral blood CD34<sup>+</sup> cells B-cell precursors differentiated from cord blood CD34<sup>+</sup> cells are more immature than those derived from granulocyte colony-stimulating factor-mobilized peripheral blood CD34<sup>+</sup> cells Immunology, 104, 4, 410-417 , 104, 4, 410-417 Immunology, 104, 4, 410-417 2001 Refereed English Disclose to all
A. Tanaka; R. Takeda; S. Mukaihara; K. Hayakawa; T. Shibata; K. Itoh; N. Nishida; K. Nakao; Y. Fukuda; T. Chiba; Y. Yamaoka A. Tanaka; R. Takeda; S. Mukaihara; K. Hayakawa; T. Shibata; K. Itoh; N. Nishida; K. Nakao; Y. Fukuda; T. Chiba; Y. Yamaoka Treatment of ruptured hepatocellular carcinoma Treatment of ruptured hepatocellular carcinoma International Journal of Clinical Oncology, 6, 6, 291-295 , 6, 6, 291-295 International Journal of Clinical Oncology, 6, 6, 291-295 2001 Refereed English Disclose to all
K. Tatsumi; T. Higuchi; H. Fujiwara; T. Nakayama; H. Egawa; K. Itoh; S. Fujii; J. Fujita K. Tatsumi; T. Higuchi; H. Fujiwara; T. Nakayama; H. Egawa; K. Itoh; S. Fujii; J. Fujita Induction of tryptophan 2,3-dioxygenase in the mouse endometrium during implantation Induction of tryptophan 2,3-dioxygenase in the mouse endometrium during implantation Biochemical and Biophysical Research Communications, 274, 1, 166-170 , 274, 1, 166-170 Biochemical and Biophysical Research Communications, 274, 1, 166-170 2000/07/21 Refereed English Disclose to all
S. Danno; K. Itoh; T. Matsuda; J. Fujita S. Danno; K. Itoh; T. Matsuda; J. Fujita Decreased expression of mouse Rbm3, a cold-shock protein, in Sertoli cells of cryptorchid testis Decreased expression of mouse Rbm3, a cold-shock protein, in Sertoli cells of cryptorchid testis American Journal of Pathology, 156, 5, 1685-1692 , 156, 5, 1685-1692 American Journal of Pathology, 156, 5, 1685-1692 2000/05 Refereed English Disclose to all
T. Tsuji; K. Itoh; C. Baum; N. Ohnishi; K. Tomiwa; D. Hirano; Y. Nishimura-Morita; W. Ostertag; J. Fujita T. Tsuji; K. Itoh; C. Baum; N. Ohnishi; K. Tomiwa; D. Hirano; Y. Nishimura-Morita; W. Ostertag; J. Fujita Retroviral vector-mediated gene expression in human CD34<sup>+</sup>CD38<sup>-</sup> cells expanded in vitro: Cis elements of FMEV are superior to those of Mo-MuLV Retroviral vector-mediated gene expression in human CD34<sup>+</sup>CD38<sup>-</sup> cells expanded in vitro: Cis elements of FMEV are superior to those of Mo-MuLV Human Gene Therapy, 11, 2, 271-284 , 11, 2, 271-284 Human Gene Therapy, 11, 2, 271-284 2000/01/20 Refereed English Disclose to all
H. Higashitsuji; K. Itoh; T. Nagao; S. Dawson; K. Nonoguchi; T. Kido; R.J. Mayer; S. Arii; J. Fujita H. Higashitsuji; K. Itoh; T. Nagao; S. Dawson; K. Nonoguchi; T. Kido; R.J. Mayer; S. Arii; J. Fujita Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas Nature Medicine, 6, 1, 96-99 , 6, 1, 96-99 Nature Medicine, 6, 1, 96-99 2000/01 Refereed English Disclose to all
J.-H. Xue; K. Nonoguchi; M. Fukumoto; T. Sato; H. Nishiyama; H. Higashitsuji; K. Itoh; J. Fujita J.-H. Xue; K. Nonoguchi; M. Fukumoto; T. Sato; H. Nishiyama; H. Higashitsuji; K. Itoh; J. Fujita Effects of ischemia and H<sub>2</sub>O<sub>2</sub> on the cold stress protein CIRP expression in rat neuronal cells Effects of ischemia and H<sub>2</sub>O<sub>2</sub> on the cold stress protein CIRP expression in rat neuronal cells Free Radical Biology and Medicine, 27, 11-12, 1238-1244 , 27, 11-12, 1238-1244 Free Radical Biology and Medicine, 27, 11-12, 1238-1244 1999/12 Refereed English Disclose to all
H. Tokuchi; H. Higashitsuji; H. Nishiyama; K. Nonoguchi; T. Nagao; J.-H. Xue; K. Itoh; O. Ogawa; J. Fujita H. Tokuchi; H. Higashitsuji; H. Nishiyama; K. Nonoguchi; T. Nagao; J.-H. Xue; K. Itoh; O. Ogawa; J. Fujita Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis International Journal of Urology, 6, 11, 572-577 , 6, 11, 572-577 International Journal of Urology, 6, 11, 572-577 1999/11 Refereed English Disclose to all
T. Higuchi; H. Fujiwara; S. Yamada; K. Tatsumi; N. Kataoka; K. Itoh; M. Maeda; J. Fujita; S. Fujii T. Higuchi; H. Fujiwara; S. Yamada; K. Tatsumi; N. Kataoka; K. Itoh; M. Maeda; J. Fujita; S. Fujii Co-expression of integrin-associated protein (IAP/CD47) and its ligand thrombospondin-1 on human granulosa and large luteal cells Co-expression of integrin-associated protein (IAP/CD47) and its ligand thrombospondin-1 on human granulosa and large luteal cells Molecular Human Reproduction, 5, 10, 920-926 , 5, 10, 920-926 Molecular Human Reproduction, 5, 10, 920-926 1999/10 Refereed English Disclose to all
K. Nonoguchi; K. Itoh; J.-H. Xue; H. Tokuchi; H. Nishiyama; Y. Kaneko; K. Tatsumi; H. Okuno; K. Tomiwa; J. Fujita K. Nonoguchi; K. Itoh; J.-H. Xue; H. Tokuchi; H. Nishiyama; Y. Kaneko; K. Tatsumi; H. Okuno; K. Tomiwa; J. Fujita Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes Gene, 237, 1, 21-28 , 237, 1, 21-28 Gene, 237, 1, 21-28 1999/09/03 Refereed English Disclose to all
S. Danno; K. Itoh; C. Baum; W. Ostertag; N. Ohnishi; T. Kido; K. Tomiwa; T. Matsuda; J. Fujita S. Danno; K. Itoh; C. Baum; W. Ostertag; N. Ohnishi; T. Kido; K. Tomiwa; T. Matsuda; J. Fujita Efficient gene transfer by hybrid retroviral vectors to murine spermatogenic cells Efficient gene transfer by hybrid retroviral vectors to murine spermatogenic cells Human Gene Therapy, 10, 11, 1819-1831 , 10, 11, 1819-1831 Human Gene Therapy, 10, 11, 1819-1831 1999/07/20 Refereed English Disclose to all
K. Tatsumi; T. Higuchi; H. Fujiwara; T. Nakayama; K. Itoh; T. Mori; S. Fujii; J. Fujita K. Tatsumi; T. Higuchi; H. Fujiwara; T. Nakayama; K. Itoh; T. Mori; S. Fujii; J. Fujita Expression of calcium binding protein D-9k messenger RNA in the mouse uterine endometrium during implantation Expression of calcium binding protein D-9k messenger RNA in the mouse uterine endometrium during implantation Molecular Human Reproduction, 5, 2, 153-161 , 5, 2, 153-161 Molecular Human Reproduction, 5, 2, 153-161 1999/02 Refereed English Disclose to all
T. Tsuji; K. Itoh; Y. Nishimura-Morita; Y. Watanabe; D. Hirano; K. Mori; K. Yatsunami T. Tsuji; K. Itoh; Y. Nishimura-Morita; Y. Watanabe; D. Hirano; K. Mori; K. Yatsunami CD34(high+)CD38(low/-) cells generated in a xenogenic coculture system are capable of both long-term hematopoiesis and multiple differentiation CD34(high+)CD38(low/-) cells generated in a xenogenic coculture system are capable of both long-term hematopoiesis and multiple differentiation Leukemia, 13, 9, 1409-1419 , 13, 9, 1409-1419 Leukemia, 13, 9, 1409-1419 1999 Refereed English Disclose to all
J.-H. Xue; H. Fukuyama; K. Nonoguchi; Y. Kaneko; T. Kido; M. Fukumoto; Y. Fujibayashi; K. Itoh; J. Fujita J.-H. Xue; H. Fukuyama; K. Nonoguchi; Y. Kaneko; T. Kido; M. Fukumoto; Y. Fujibayashi; K. Itoh; J. Fujita Induction of Apg-1, a member of the heat shock protein 110 family, following transient forebrain ischemia in the rat brain Induction of Apg-1, a member of the heat shock protein 110 family, following transient forebrain ischemia in the rat brain Biochemical and Biophysical Research Communications, 247, 3, 796-801 , 247, 3, 796-801 Biochemical and Biophysical Research Communications, 247, 3, 796-801 1998/06/29 Refereed English Disclose to all
H. Nishiyama; S. Danno; Y. Kaneko; K. Itoh; H. Yokoi; M. Fukumoto; H. Okuno; J.L. Millán; T. Matsuda; O. Yoshida; J. Fujita H. Nishiyama; S. Danno; Y. Kaneko; K. Itoh; H. Yokoi; M. Fukumoto; H. Okuno; J.L. Millán; T. Matsuda; O. Yoshida; J. Fujita Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature American Journal of Pathology, 152, 1, 289-296 , 152, 1, 289-296 American Journal of Pathology, 152, 1, 289-296 1998/01 Refereed English Disclose to all
H. Nishiyama; H. Higashitsuji; H. Yokoi; K. Itoh; S. Danno; T. Matsuda; J. Fujita H. Nishiyama; H. Higashitsuji; H. Yokoi; K. Itoh; S. Danno; T. Matsuda; J. Fujita Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene Gene, 204, 1-2, 115-120 , 204, 1-2, 115-120 Gene, 204, 1-2, 115-120 1997/12/19 Refereed English Disclose to all
S. Danno; H. Nishiyama; H. Higashitsuji; H. Yokoi; J.-H. Xue; K. Itoh; T. Matsuda; J. Fujita S. Danno; H. Nishiyama; H. Higashitsuji; H. Yokoi; J.-H. Xue; K. Itoh; T. Matsuda; J. Fujita Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress Biochemical and Biophysical Research Communications, 236, 3, 804-807 , 236, 3, 804-807 Biochemical and Biophysical Research Communications, 236, 3, 804-807 1997/07/30 Refereed English Disclose to all
H. Nishiyama; K. Itoh; Y. Kaneko; M. Kishishita; O. Yoshida; J. Fujita H. Nishiyama; K. Itoh; Y. Kaneko; M. Kishishita; O. Yoshida; J. Fujita A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth Journal of Cell Biology, 137, 4, 899-908 , 137, 4, 899-908 Journal of Cell Biology, 137, 4, 899-908 1997/05/19 Refereed English Disclose to all
K. Okumura; Y. Kaneko; K. Nonoguchi; H. Nishiyama; H. Yokoi; T. Higuchi; K. Itoh; O. Yoshida; T. Miki; J. Fujita K. Okumura; Y. Kaneko; K. Nonoguchi; H. Nishiyama; H. Yokoi; T. Higuchi; K. Itoh; O. Yoshida; T. Miki; J. Fujita Expression of a novel isoform of Vav, Vav-T, containing a single Src homology 3 domain in murine testicular germ cells Expression of a novel isoform of Vav, Vav-T, containing a single Src homology 3 domain in murine testicular germ cells Oncogene, 14, 6, 713-720 , 14, 6, 713-720 Oncogene, 14, 6, 713-720 1997/02/13 Refereed English Disclose to all
K. Itoh; J. Friel; C. Laker; W. Zeller; U. Just; S. Bittner; R.J.B. Nibbs; P.R. Harrison; S.-I. Nishikawa; K.J. Mori; W. Ostertag K. Itoh; J. Friel; C. Laker; W. Zeller; U. Just; S. Bittner; R.J.B. Nibbs; P.R. Harrison; S.-I. Nishikawa; K.J. Mori; W. Ostertag The role of soluble growth factors in inducing transient growth and clonal extinction of stroma cell dependent erythroblastic leukemia cells The role of soluble growth factors in inducing transient growth and clonal extinction of stroma cell dependent erythroblastic leukemia cells Leukemia, 11, 10, 1753-1761 , 11, 10, 1753-1761 Leukemia, 11, 10, 1753-1761 1997 Refereed English Disclose to all
C. Baum; K. Itoh; J. Meyer; C. Laker; Y. Ito; W. Ostertag C. Baum; K. Itoh; J. Meyer; C. Laker; Y. Ito; W. Ostertag The potent enhancer activity of the polycythemic strain of spleen focus- forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PEBP/C The potent enhancer activity of the polycythemic strain of spleen focus- forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PEBP/C Journal of Virology, 71, 9, 6323-6331 , 71, 9, 6323-6331 Journal of Virology, 71, 9, 6323-6331 1997 Refereed English Disclose to all
J. Friel; C. Heberlein; K. Itoh; W. Ostertag J. Friel; C. Heberlein; K. Itoh; W. Ostertag Role of the stem cell factor (SCF) receptor and the alternative forms of its ligand (SCF) in the induction of long term growth by stroma cells Role of the stem cell factor (SCF) receptor and the alternative forms of its ligand (SCF) in the induction of long term growth by stroma cells Leukemia, 11, SUPPL. 3, 493-495 , 11, SUPPL. 3, 493-495 Leukemia, 11, SUPPL. 3, 493-495 1997 Refereed English Disclose to all
K. Itoh; J. Friel; N. Kluge; T. Kina; A. Kondo-Takaori; S. Kawamata; T. Uchiyama; W. Ostertag K. Itoh; J. Friel; N. Kluge; T. Kina; A. Kondo-Takaori; S. Kawamata; T. Uchiyama; W. Ostertag A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell-dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction A novel hematopoietic multilineage clone, Myl-D-7, is stromal cell-dependent and supported by an alternative mechanism(s) independent of stem cell factor/c-kit interaction Blood, 87, 8, 3218-3228 , 87, 8, 3218-3228 Blood, 87, 8, 3218-3228 1996/04/15 Refereed English Disclose to all
R.J.B. Nibbs; K. Itoh; W. Ostertag; P.R. Harrison R.J.B. Nibbs; K. Itoh; W. Ostertag; P.R. Harrison Differentiation arrest and stromal cell-independent growth of murine erythroleukemia cells are associated with elevated expression of ets-related genes but not with mutation of p53 Differentiation arrest and stromal cell-independent growth of murine erythroleukemia cells are associated with elevated expression of ets-related genes but not with mutation of p53 Molecular and Cellular Biology, 13, 9, 5582-5592 , 13, 9, 5582-5592 Molecular and Cellular Biology, 13, 9, 5582-5592 1993 Refereed English Disclose to all
K. Imada; M. Tsudo; T.-i. Kodaka; K. Itoh; N. Arima; T. Hattori; M. Okuma; T. Uchiyama K. Imada; M. Tsudo; T.-i. Kodaka; K. Itoh; N. Arima; T. Hattori; M. Okuma; T. Uchiyama Interleukin-2 (IL-2) induces erythroid differentiation and tyrosine phosphorylation in ELM-I-1 cells transfected with a human IL-2 receptor β chain cDNA Interleukin-2 (IL-2) induces erythroid differentiation and tyrosine phosphorylation in ELM-I-1 cells transfected with a human IL-2 receptor β chain cDNA Biochemical and Biophysical Research Communications, 188, 1, 352-357 , 188, 1, 352-357 Biochemical and Biophysical Research Communications, 188, 1, 352-357 1992 Refereed English Disclose to all
M. Kamio; T. Uchiyama; N. Arima; K. Itoh; T. Ishikawa; T. Hori; H. Uchino M. Kamio; T. Uchiyama; N. Arima; K. Itoh; T. Ishikawa; T. Hori; H. Uchino Role of α chain-IL-2 complex in the formation of the ternary complex of IL-2 and high-affinity IL-2 receptor Role of α chain-IL-2 complex in the formation of the ternary complex of IL-2 and high-affinity IL-2 receptor International Immunology, 2, 6, 521-530 , 2, 6, 521-530 International Immunology, 2, 6, 521-530 1990 Refereed English Disclose to all
T. Kodaka; T. Uchiyama; T. Ishikawa; M. Kamio; R. Onishi; K. Itoh; T. Hori; H. Uchino; M. Tsudo; K. Araki T. Kodaka; T. Uchiyama; T. Ishikawa; M. Kamio; R. Onishi; K. Itoh; T. Hori; H. Uchino; M. Tsudo; K. Araki Interleukin-2 receptor β-chain (p70-75) expressed on leukemic cells from adult T cell leukemia patients Interleukin-2 receptor β-chain (p70-75) expressed on leukemic cells from adult T cell leukemia patients Japanese Journal of Cancer Research, 81, 9, 902-908 , 81, 9, 902-908 Japanese Journal of Cancer Research, 81, 9, 902-908 1990 Refereed English Disclose to all
T. Motoi; T. Uchiyama; T. Hori; K. Itoh; H. Uchino; R. Ueda T. Motoi; T. Uchiyama; T. Hori; K. Itoh; H. Uchino; R. Ueda Elevated serum-soluble interleukin-2 receptor (Tac antigen) levels in chronic myelogenous leukemia patients with blastic crisis Elevated serum-soluble interleukin-2 receptor (Tac antigen) levels in chronic myelogenous leukemia patients with blastic crisis Blood, 74, 3, 1052-1057 , 74, 3, 1052-1057 Blood, 74, 3, 1052-1057 1989 Refereed English Disclose to all
伊藤克彦,藤田潤 伊藤克彦,藤田潤 造血幹細胞のin vivo における増殖・分化機構の解析 \nMechanisms regulating the proliferation and differentiation of hematopoietic stem cells in vivo 造血幹細胞のin vivo における増殖・分化機構の解析 \nMechanisms regulating the proliferation and differentiation of hematopoietic stem cells in vivo (京大院・医) (京大院・医) Refereed English Disclose to all

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Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Interaction of cold-inducible RNA-binding protein with Dyrk1b regulates early spermatogenesis. Interaction of cold-inducible RNA-binding protein with Dyrk1b regulates early spermatogenesis. Hannover Medial School. Hannover, Germany. Hannover Medial School. Hannover, Germany. 2011/11/15 English Oral presentation(invited, special) Disclose to all
Regulation of spermatogenesis by a cold inducible protein, CIRP. Regulation of spermatogenesis by a cold inducible protein, CIRP. Mechanisms of early differentiation: embryogenesis, myogenesis (cardiac differentiation) and hematopoiesis/lymphopoiesis. Mechanisms of early differentiation: embryogenesis, myogenesis (cardiac differentiation) and hematopoiesis/lymphopoiesis. 2008/09/01 English Oral presentation(invited, special) Disclose to all
Title language:
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
挑戦的萌芽研究 Representative 繊維芽細胞から造血幹細胞へのリプログラミング技法 2011-2013
External funds: other than those above
System Main person Title(Japanese) Title(English) Period
日本医療研究開発機構 感染症実用化研究事業 伊藤　義人 分子シャペロンAPG-2による非アルコール性脂肪性肝疾患の制御と、その機序に基づく疾患予後評価法、治療法の開発 2017/04/01-2020/03/31
Faculty management (title, position)
Title Period
病院運営委員会、廃液処理委員会 -
動物実験施設運営委員会 2013/04/01-2017/03/31

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