山門穂高

Last Update: 2020/09/18 14:17:07

Name(Kanji/Kana/Abecedarium Latinum)

山門穂高/ヤマカドホダカ/Yamakado, Hodaka

Primary Affiliation(Org1/Job title)

Kyoto University Hospital/Program-Specific Associate Professor

Contact Address

Type	Address(Japanese)	Address(English)
Office	京都市左京区聖護院川原町５４　京都大学医学部付属病院神経内科

Phone

Type	Number
Office	075-751-3767

Academic Organizations You are Affiliated to in Japan

Organization name(Japanese)	Organization name(English)
日本神経学会	Japanese society of neurology
日本内科学会	Japanese Society of Internal Medicine

Academic Organizations Overaseas You are Affiliated to

Organization name	Country
Society For Neuroscience	米国
International Parkinson and Movement Disorder Society

Academic Degree

Field(Japanese)	Field(English)	University(Japanese)	University(English)	Method
博士（医学）		京都大学

Graduate School

University(Japanese)	University(English)	Faculty(Japanese)	Faculty(English)	Major(Japanese)	Major(English)	Degree
京都大学		大学院医学研究科博士課程脳統御医科学専攻				修了

Undergraduate School / Major(s)

University(Japanese)	University(English)	Faculty(Japanese)	Faculty(English)	Major(s)(Japanese)	Major(s)(English)	Degree
京都大学		医学部医学科				卒業

High School

Highschool	Kana
三重高田高等学校	みえたかだこうとうがっこう

Work Experience

Period	Organization(Japanese)	Organization(English)	Job title(Japanese)	Job title(English)
2000/4-2003/3	虎の門病院　内科	Department of Internal Medicine, Toranomon Hospital	研修医	Resident
2003/4-2005/3	京都大学医学部付属病院　神経内科	Department of Neurology, Kyoto University Hospital	医員	Clinical fellow
2009/4-2010/9	京都大学医学部付属病院　神経内科	Department of Neurology, Kyoto University Hospital	助教	Assistant professor
2010/10/-2011/3	武田総合病院　神経内科	Department of Neurology, Takeda General Hospital	医長	Clinical fellow
2011/4-2019/03/31	京都大学医学部付属病院　神経内科	Department of Neurology, Kyoto University Hospital	助教	Assistant professor
2019/04/01-	京都大学医学部附属病院　脳神経内科	Department of Neurology Kyoto University Hospital	特定准教授	Research Associate Professor

Personal Profile

(Japanese)
研究においては、様々なモデル動物を用いたパーキンソン病・多系統委縮症の病態解析・治療法開発、臨床においては京都大学病院においてパーキンソン病を中心とした神経内科の一般診療を行っている。
(English)
My research interest is focused on the pathomechanism of Parkinson's disease (PD) / multiple system atrophy (MSA) and development of novel therapeutics for PD/MSA. Also, I am working as a general neurologist at Kyoto University Hospital .

Language of Instruction

Language(japanese)	Language(english)	Code
英語	English	eng

researchmap URL

https://researchmap.jp/7000008893

Research Topics

(Japanese)
神経変性疾患の分子生物学的研究
(English)
Molecular biology of neurodegenerative disorders

Overview of the research

(Japanese)
神経変性疾患、特にパーキンソン病（Parkinson's disease, PD)や多系統萎縮症において、様々なモデル動物（マウス、ラット、メダカ）やiPS細胞を用いてモデル動物の開発、病態メカニズムの解明、新規治療法の開発を目指した研究を行っている。特にα-synucleinやglucocerebrosidase (GBA)といった孤発性PDに深く関与する分子を中心とした研究を行っている。
(English)
My research is fosused on the development of model for Parkinson's disease and multiple system atrophy using mice, rat, medaka fish and patients-derived iPS cells as well as investigation of pathomechanisms underlying PD and development of novel therapeutics for PD.

Fields of research (key words)

Key words(Japanese)	Key words(English)
神経内科学	Neurology

Published Papers

Author	Author(Japanese)	Author(English)	Title	Title(Japanese)	Title(English)	Bibliography	Bibliography(Japanese)	Bibliography(English)	Publication date	Refereed paper	Language	Publishing type	Disclose
Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi	Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi	Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado, Ryosuke Takahashi	BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy.	BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy.	BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy.	Acta neuropathologica communications, 8, 1, 120-120	Acta neuropathologica communications, 8, 1, 120-120	Acta neuropathologica communications, 8, 1, 120-120	2020/07/29	Refereed	English	Research paper(scientific journal)	Disclose to all
Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa	Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa	Tomonori Hoshino, Hodaka Yamakado, Ryosuke Takahashi, Shu-Ichi Matsuzawa	Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.	Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.	Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.	FEBS open bio	FEBS open bio	FEBS open bio	2020/07/01	Refereed	English	Research paper(scientific journal)	Disclose to all
Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura	Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura	Paeksoon Park, Hodaka Yamakado, Ryosuke Takahashi, Shikiho Dote, Shiho Ubukata, Toshiya Murai, Takashi Tsukiura	Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease.	Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease.	Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease.	Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429	Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429	Journal of the International Neuropsychological Society : JINS, 26, 4, 418-429	2020/04	Refereed	English	Research paper(scientific journal)	Disclose to all
Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi	Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi	Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi	Animal Model for Prodromal Parkinson's Disease.	Animal Model for Prodromal Parkinson's Disease.	Animal Model for Prodromal Parkinson's Disease.	International journal of molecular sciences, 21, 6	International journal of molecular sciences, 21, 6	International journal of molecular sciences, 21, 6	2020/03/13	Refereed	English	Research paper(scientific journal)	Disclose to all
Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi	Uemura N, Yagi H, Uemura MT, Yamakado H, Takahashi R	Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi	Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract.	Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract.	Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract.	Neuroscience letters, 716, 134651-134651	Neuroscience letters, 716, 134651-134651	Neuroscience letters, 716, 134651-134651	2020/01/18	Refereed	English	Research paper(scientific journal)	Disclose to all
Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi	Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi	Sumio Minamiyama, Sakiho Ueda, Ran Nakashima, Hodaka Yamakado, Yusuke Sakato, Hirofumi Yamashita, Nobukatsu Sawamoto, Ryota Fujimoto, Ichizo Nishino, Makoto Urushitani, Tsuneyo Mimori, Ryosuke Takahashi	Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody.	Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody.	Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody.	Muscle & nerve, 61, 1, 81-87	Muscle & nerve, 61, 1, 81-87	Muscle & nerve, 61, 1, 81-87	2020/01	Refereed	English	Research paper(scientific journal)	Disclose to all
Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi	Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi	Seiji Kaji, Takakuni Maki, Tomoyuki Ishimoto, Hodaka Yamakado, Ryosuke Takahashi	Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions.	Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions.	Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions.	Translational neurodegeneration, 9, 7-7	Translational neurodegeneration, 9, 7-7	Translational neurodegeneration, 9, 7-7	2020	Refereed	English	Research paper(scientific journal)	Disclose to all
Tomoyuki Taguchi, Masashi Ikuno, Mari Hondo, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Jun Ueda, Masanori Sawamura, Shinya Okuda, Etsuro Nakanishi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Takashi Ayaki, Shuichi Matsuzawa, Masaki Tanaka, Omar M A El-Agnaf, Masato Koike, Masashi Yanagisawa, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi	Taguchi T, Ikuno M, Hondo M, Parajuli LK, Taguchi K, Ueda J, Sawamura M, Okuda S, Nakanishi E, Hara J, Uemura N, Hatanaka Y, Ayaki T, Matsuzawa S, Tanaka M, El-Agnaf OMA, Koike M, Yanagisawa M, Uemura MT, Yamakado H, Takahashi R	Tomoyuki Taguchi, Masashi Ikuno, Mari Hondo, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Jun Ueda, Masanori Sawamura, Shinya Okuda, Etsuro Nakanishi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Takashi Ayaki, Shuichi Matsuzawa, Masaki Tanaka, Omar M A El-Agnaf, Masato Koike, Masashi Yanagisawa, Maiko T Uemura, Hodaka Yamakado, Ryosuke Takahashi	α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.	α-Synuclein BAC transgenic mice exhibited RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.	α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.	Brain : a journal of neurology, 143, 1, 249-265	Brain, 143, 1, 249-265	Brain : a journal of neurology, 143, 1, 249-265	2020/01/01	Refereed	English	Research paper(scientific journal)	Disclose to all
Ishimoto T, Yamakado H	Ishimoto T, Yamakado H	Ishimoto T, Yamakado H	TPPP/p25α Is an old and new therapeutic target in multiple system atrophy.	TPPP/p25α Is an old and new therapeutic target in multiple system atrophy.	TPPP/p25α Is an old and new therapeutic target in multiple system atrophy.	Movement disorders	Movement disorders	Movement disorders	2019/11	Refereed			Disclose to all
Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Yusuke Hatanaka, Hodaka Yamakado, Ryosuke Takahashi	Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R	Norihito Uemura, Hisashi Yagi, Maiko T Uemura, Yusuke Hatanaka, Hodaka Yamakado, Ryosuke Takahashi	Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Molecular neurodegeneration, 14, 1, 31-31	Mol Neurodegener, 14, 1, 31-31	Molecular neurodegeneration, 14, 1, 31-31	2019/07/26	Refereed	English	Research paper(scientific journal)	Disclose to all
Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi	Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi	Masashi Ikuno, Hodaka Yamakado, Hisako Akiyama, Laxmi Kumar Parajuli, Katsutoshi Taguchi, Junko Hara, Norihito Uemura, Yusuke Hatanaka, Katsumi Higaki, Kousaku Ohno, Masaki Tanaka, Masato Koike, Yoshio Hirabayashi, Ryosuke Takahashi	GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.	GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.	GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.	Human molecular genetics, 28, 11, 1894-1904	Human molecular genetics, 28, 11, 1894-1904	Human molecular genetics, 28, 11, 1894-1904	2019/06/01	Refereed	English	Research paper(scientific journal)	Disclose to all
Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M	Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M	Tojima M, Murakami G, Hikawa R, Yamakado H, Yamashita H, Takahashi R, Matsui M	Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia.	Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia.	Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia.	Neurology. Genetics, 4, 6, e283	Neurology. Genetics, 4, 6, e283	Neurology. Genetics, 4, 6, e283	2018/12	Refereed			Disclose to all
Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda	Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda	Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Yosuke Yamada, Hodaka Yamakado, Shuichi Matsuda	Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN)	Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN)	Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN)	American Journal of Case Reports, 19, 1249-1252	American Journal of Case Reports, 19, 1249-1252	American Journal of Case Reports, 19, 1249-1252	2018/10/20	Refereed		Research paper(scientific journal)	Disclose to all
Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E	Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E	Kim C, Spencer B, Rockenstein E, Yamakado H, Mante M, Adame A, Fields JA, Masliah D, Iba M, Lee HJ, Rissman RA, Lee SJ, Masliah E	Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.	Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.	Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.	Molecular neurodegeneration, 13, 1, 43	Molecular neurodegeneration, 13, 1, 43	Molecular neurodegeneration, 13, 1, 43	2018/08	Refereed			Disclose to all
Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H	Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H	Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H	Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.	Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.	Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.	eNeuro, 5, 4	eNeuro, 5, 4	eNeuro, 5, 4	2018/07	Refereed			Disclose to all
Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R	Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R	Uemura N, Yagi H, Uemura MT, Hatanaka Y, Yamakado H, Takahashi R	Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.	Molecular neurodegeneration, 13, 1, 21	Molecular neurodegeneration, 13, 1, 21	Molecular neurodegeneration, 13, 1, 21	2018/05	Refereed			Disclose to all
Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R	Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R	Hikiami R, Yamakado H, Tatsumi S, Ayaki T, Hashi Y, Yamashita H, Sawamoto N, Tsuji T, Urushitani M, Takahashi R	Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl.	Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl.	Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl.	Internal medicine, 57, 13, 1917-1919	Internal medicine, 57, 13, 1917-1919	Internal medicine, 57, 13, 1917-1919	2018/02	Refereed			Disclose to all
Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi	Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi	Maiko T. Uemura, Takeshi Asano, Rie Hikawa, Hodaka Yamakado, Ryosuke Takahashi	Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity	Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity	Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity	NEUROSCIENCE RESEARCH, 124, 25-32	NEUROSCIENCE RESEARCH, 124, 25-32	NEUROSCIENCE RESEARCH, 124, 25-32	2017/11	Refereed	English	Research paper(scientific journal)	Disclose to all
Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi	Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi	Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Keisuke Okita, Masato Nakagawa, Hodaka Yamakado, Haruhisa Inoue, Ryosuke Takahashi, Jun Takahashi	Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains	Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains	Idiopathic Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Function as Midbrain Dopaminergic Neurons in Rodent Brains	JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837	JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837	JOURNAL OF NEUROSCIENCE RESEARCH, 95, 9, 1829-1837	2017/09	Refereed	English	Research paper(scientific journal)	Disclose to all
Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi	Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi	Naho Saito, Keisuke Takahata, Hodaka Yamakado, Nobukatsu Sawamoto, Satoshi Saito, Ryosuke Takahashi, Toshiya Murai, Hidehiko Takahashi	Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures	Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures	Altered awareness of action in Parkinson's disease: evaluations by explicit and implicit measures	SCIENTIFIC REPORTS, 7, 1, 8019	SCIENTIFIC REPORTS, 7, 1, 8019	SCIENTIFIC REPORTS, 7, 1, 8019	2017/08	Refereed	English	Research paper(scientific journal)	Disclose to all
Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah	Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah	Elisabet Ihse, Hodaka Yamakado, Xander M. van Wijk, Roger Lawrence, Jeffrey D. Esko, Eliezer Masliah	Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type	Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type	Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type	SCIENTIFIC REPORTS, 7, 1, 9008	SCIENTIFIC REPORTS, 7, 1, 9008	SCIENTIFIC REPORTS, 7, 1, 9008	2017/08	Refereed	English	Research paper(scientific journal)	Disclose to all
Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi	Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi	Hisanori Kinoshita, Hodaka Yamakado, Toshiyuki Kitano, Akihiro Kitamura, Hirofumi Yamashita, Masakazu Miyamoto, Takefumi Hitomi, Tomohisa Okada, Yuji Nakamoto, Nobukatsu Sawamoto, Akifumi Takaori-Kondo, Ryosuke Takahashi	Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases	Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases	Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases	JOURNAL OF NEUROLOGY, 263, 9, 1719-1726	JOURNAL OF NEUROLOGY, 263, 9, 1719-1726	JOURNAL OF NEUROLOGY, 263, 9, 1719-1726	2016/09	Refereed	English	Research paper(scientific journal)	Disclose to all
Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi	Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi	Mio Hamatani, Naoto Jingami, Kengo Uemura, Naoe Nakasone, Hisanori Kinoshita, Hodaka Yamakado, Haruaki Ninomiya, Ryosuke Takahashi	A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome	A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome	A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome	Clinical Neurology, 56, 6, 424-429	Clinical Neurology, 56, 6, 424-429	Clinical Neurology, 56, 6, 424-429	2016	Refereed	Japanese	Research paper(scientific journal)	Disclose to all
Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi	Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi	Norihito Uemura, Masato Koike, Satoshi Ansai, Masato Kinoshita, Tomoko Ishikawa-Fujiwara, Hideaki Matsui, Kiyoshi Naruse, Naoaki Sakamoto, Yasuo Uchiyama, Takeshi Todo, Shunichi Takeda, Hodaka Yamakado, Ryosuke Takahashi	Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein	Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein	Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein	PLOS GENETICS, 11, 4, e1005065	PLOS GENETICS, 11, 4, e1005065	PLOS GENETICS, 11, 4, e1005065	2015/04	Refereed	English	Research paper(scientific journal)	Disclose to all
Hodaka Yamakado	Hodaka Yamakado	Hodaka Yamakado	Advance in PD Research Explored a New Field on Ubiquitin Biology	Advance in PD Research Explored a New Field on Ubiquitin Biology	Advance in PD Research Explored a New Field on Ubiquitin Biology	MOVEMENT DISORDERS, 29, 10, 1243-1243	MOVEMENT DISORDERS, 29, 10, 1243-1243	MOVEMENT DISORDERS, 29, 10, 1243-1243	2014/09	Refereed	English		Disclose to all
Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi	Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi	Hideaki Matsui, Norihito Uemura, Hodaka Yamakado, Shunichi Takeda, Ryosuke Takahashi	Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish	Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish	Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish	JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310	JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310	JOURNAL OF PARKINSONS DISEASE, 4, 2, 301-310	2014	Refereed	English		Disclose to all
Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi	Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi	Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi	Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody	Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody	Two cases of acute onset of focal cortical reflex myoclonus following acute aseptic meningoencephalitis with positive anti-glutamate receptor autoantibody	Clinical Neurology, 54, 7, 543-549	Clinical Neurology, 54, 7, 543-549	Clinical Neurology, 54, 7, 543-549	2014	Refereed	English	Research paper(scientific journal)	Disclose to all
Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi	Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi	Eiko N. Minakawa, Hodaka Yamakado, Atsushi Tanaka, Kengo Uemura, Shunichi Takeda, Ryosuke Takahashi	Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction	Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction	Chicken DT40 cell line lacking DJ-1, the gene responsible for familial Parkinson's disease, displays mitochondrial dysfunction	NEUROSCIENCE RESEARCH, 77, 4, 228-233	NEUROSCIENCE RESEARCH, 77, 4, 228-233	NEUROSCIENCE RESEARCH, 77, 4, 228-233	2013/12	Refereed	English	Research paper(scientific journal)	Disclose to all
Ryosuke Takahashi, Hodaka Yamakado	Ryosuke Takahashi, Hodaka Yamakado	Ryosuke Takahashi, Hodaka Yamakado	Genetic correction will be a standard method for the patient-derived ips cell research?	Genetic correction will be a standard method for the patient-derived ips cell research?	Genetic correction will be a standard method for the patient-derived ips cell research?	Movement Disorders, 28, 14, 1935-1935	Movement Disorders, 28, 14, 1935-1935	Movement Disorders, 28, 14, 1935-1935	2013/12	Refereed	English	Research paper(scientific journal)	Disclose to all
Hodaka Yamakado, Ryosuke Takahashi	Hodaka Yamakado, Ryosuke Takahashi	Hodaka Yamakado, Ryosuke Takahashi	The Function of Parkin: Revisited	The Function of Parkin: Revisited	The Function of Parkin: Revisited	MOVEMENT DISORDERS, 28, 14, 1936-1936	MOVEMENT DISORDERS, 28, 14, 1936-1936	MOVEMENT DISORDERS, 28, 14, 1936-1936	2013/12	Refereed	English		Disclose to all
Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita	Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita	Natsumi Ageta-Ishihara, Hodaka Yamakado, Takao Morita, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Ryosuke Takahashi, Makoto Kinoshita	Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice	Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice	Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice	MOLECULAR BRAIN, 6, 35	MOLECULAR BRAIN, 6, 35	MOLECULAR BRAIN, 6, 35	2013/08	Refereed	English	Research paper(scientific journal)	Disclose to all
Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi	Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi	Hideaki Matsui, Roberto Gavinio, Takeshi Asano, Norihito Uemura, Hidefumi Ito, Yoshihito Taniguchi, Yoshito Kobayashi, Takakuni Maki, Jie Shen, Shunichi Takeda, Kengo Uemura, Hodaka Yamakado, Ryosuke Takahashi	PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates	PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates	PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates	HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434	HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434	HUMAN MOLECULAR GENETICS, 22, 12, 2423-2434	2013/06	Refereed	English	Research paper(scientific journal)	Disclose to all
Silke Nuber, Florian Harmuth, Zacharias Kohl, Anthony Adame, Margaritha Trejo, Kai Schönig, Frank Zimmermann, Claudia Bauer, Nicolas Casadei, Christiane Giel, Carsten Calaminus, Bernd J. Pichler, Poul H. Jensen, Christian P. Müller, Davide Amato, Johannes Kornhuber, Peter Teismann, Hodaka Yamakado, Ryosuke Takahashi, Juergen Winkler, Eliezer Masliah, Olaf Riess	Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O	Silke Nuber, Florian Harmuth, Zacharias Kohl, Anthony Adame, Margaritha Trejo, Kai Schönig, Frank Zimmermann, Claudia Bauer, Nicolas Casadei, Christiane Giel, Carsten Calaminus, Bernd J. Pichler, Poul H. Jensen, Christian P. Müller, Davide Amato, Johannes Kornhuber, Peter Teismann, Hodaka Yamakado, Ryosuke Takahashi, Juergen Winkler, Eliezer Masliah, Olaf Riess	A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats	A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.	A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats	Brain, 136, 2, 412-432	Brain, 136, 2, 412-432	Brain, 136, 2, 412-432	2013	Refereed	English	Research paper(scientific journal)	Disclose to all
Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Junko Kurisu, Kengo Uemura, Haruhisa Inoue, Makio Takahashi, Ryosuke Takahashi	Yamakado H, Moriwaki Y, Yamasaki N, Miyakawa T, Kurisu J, Uemura K, Inoue H, Takahashi M, Takahashi R	Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Junko Kurisu, Kengo Uemura, Haruhisa Inoue, Makio Takahashi, Ryosuke Takahashi	alpha-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion	α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion.	alpha-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion	NEUROSCIENCE RESEARCH, 73, 2, 173-177	Neuroscience research, 73, 2, 173-177	NEUROSCIENCE RESEARCH, 73, 2, 173-177	2012/06	Refereed	English	Research paper(scientific journal)	Disclose to all
Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda	Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda	Takayuki Kondo, Hodaka Yamakado, Jun Kawamata, Hidekazu Tomimoto, Takefumi Hitomi, Ryosuke Takahashi, Akio Ikeda	Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report	Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report	Unverricht-Lundborg disease manifesting tremulous myoclonus with rare convulsive seizures: A case report	Clinical Neurology, 49, 1, 43-47	Clinical Neurology, 49, 1, 43-47	Clinical Neurology, 49, 1, 43-47	2009	Refereed	Japanese	Research paper(scientific journal)	Disclose to all
H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama	H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama	H Sawada, K Yamakawa, H Yamakado, R Hosokawa, M Ohba, K Miyamoto, T Kawamura, S Shimohama	Cocaine and phenylephrine eye drop test for Parkinson disease	Cocaine and phenylephrine eye drop test for Parkinson disease	Cocaine and phenylephrine eye drop test for Parkinson disease	JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934	JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934	JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 293, 8, 932-934	2005/02	Refereed	English		Disclose to all
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Misc

Author	Author(Japanese)	Author(English)	Title	Title(Japanese)	Title(English)	Bibliography	Bibliography(Japanese)	Bibliography(English)	Publication date	Language	Publishing type	Disclose
引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔	引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔	引網亮太, 端祐一郎, 山門穂高, 辰己新水, 山下博史, 澤本伸克, 辻輝之, 川本未知, 幸原伸夫, 井上治久, 漆谷真, 高橋良輔	FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像：若年発症例を含む4症例の検討	FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像：若年発症例を含む4症例の検討	FUS遺伝子変異を伴う筋萎縮性側索硬化症の臨床像：若年発症例を含む4症例の検討	56th Annual Meeting of the Japanese Society of Neurology, Niigata.	56th Annual Meeting of the Japanese Society of Neurology, Niigata.	56th Annual Meeting of the Japanese Society of Neurology, Niigata.	2015/05/21			Disclose to all
Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi	Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi	Yasushi Koshiba, Hodaka Yamakado, Asuka Morizane, Tetsuhiro Kikuchi, Kazuko Hasegawa, Haruhisa Inoue, Jun Takahashi, Ryosuke Takahashi	iPS cell modeling of genetic Parkinson's disease	iPS cell modeling of genetic Parkinson's disease	iPS cell modeling of genetic Parkinson's disease	MOVEMENT DISORDERS, 29, S68-S68	MOVEMENT DISORDERS, 29, S68-S68	MOVEMENT DISORDERS, 29, S68-S68	2014/11	English	Research paper, summary (international conference)	Disclose to all
N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi	N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi	N. Uemura, H. Matsui, T. Fujiwara-Ishikawa, M. Kinoshita, M. Koike, H. Yamakado, K. Uemura, Y. Uchiyama, T. Todo, S. I. Takeda, R. Takahashi	Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain	Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain	Viable Gaucher's disease model of medaka fish completely deficienct in glucocerebrosidase activity developed alpha-synuclein aggregation in the brain	MOVEMENT DISORDERS, 28, S373-S374	MOVEMENT DISORDERS, 28, S373-S374	MOVEMENT DISORDERS, 28, S373-S374	2013/06	English	Research paper, summary (international conference)	Disclose to all
H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi	H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi	H. Yamakado, Y. Moriwaki, N. Yamasaki, T. Miyakawa, J. Kurisu, K. Uemura, H. Inoue, M. Takahashi, R. Takahashi	alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior	alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior	alpha-synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior	MOVEMENT DISORDERS, 27, S498-S498	MOVEMENT DISORDERS, 27, S498-S498	MOVEMENT DISORDERS, 27, S498-S498	2012/06	English	Research paper, summary (international conference)	Disclose to all
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Makio Takahashi, Ryosuke Takahashi	Pael-R, a substrate of Parkin, can also be cleared by PINK1	Pael-R, a substrate of Parkin, can also be cleared by PINK1	Pael-R, a substrate of Parkin, can also be cleared by PINK1	NEUROSCIENCE RESEARCH, 71, E192-E192	NEUROSCIENCE RESEARCH, 71, E192-E192	NEUROSCIENCE RESEARCH, 71, E192-E192	2011	English	Research paper, summary (international conference)	Disclose to all
Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	Hodaka Yamakado, Yasuhiro Moriwaki, Nobuyuki Yamasaki, Junko Kurisu, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease	Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease	Decreased anxiety-like behavior in alpha-synuclein BAC transgenic mice recapitulates early non-motor symptoms in Parkinson disease	NEUROSCIENCE RESEARCH, 71, E189-E189	NEUROSCIENCE RESEARCH, 71, E189-E189	NEUROSCIENCE RESEARCH, 71, E189-E189	2011	English	Research paper, summary (international conference)	Disclose to all
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	PaelR, a substrate of Parkin, can also be decreased by PINK1	PaelR, a substrate of Parkin, can also be decreased by PINK1	PaelR, a substrate of Parkin, can also be decreased by PINK1	NEUROSCIENCE RESEARCH, 68, E258-E258	NEUROSCIENCE RESEARCH, 68, E258-E258	NEUROSCIENCE RESEARCH, 68, E258-E258	2010	English	Research paper, summary (international conference)	Disclose to all
Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	Roberto Gavinio, Hodaka Yamakado, Tomoyo Sawada, Akira Kuzuya, Ryosuke Takahashi	PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures	PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures	PINK1 promotes the clearance of unfolded Pael-R in mammalian cell cultures	NEUROSCIENCE RESEARCH, 65, S118-S118	NEUROSCIENCE RESEARCH, 65, S118-S118	NEUROSCIENCE RESEARCH, 65, S118-S118	2009	English	Research paper, summary (international conference)	Disclose to all
Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	Hodaka Yamakado, Yasuhiro Moriwaki, Jyunko Kurisu, Naoko Tsunekawa, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Kengo Uemura, Haruhisa Inoue, Ryosuke Takahashi	PARK4 mouse model	PARK4 mouse model	PARK4 mouse model	NEUROSCIENCE RESEARCH, 61, S265-S265	NEUROSCIENCE RESEARCH, 61, S265-S265	NEUROSCIENCE RESEARCH, 61, S265-S265	2008	English	Research paper, summary (international conference)	Disclose to all
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Conference Activities & Talks

Title	Title(Japanese)	Title(English)	Conference	Conference(Japanese)	Date	Language	Assortment	Disclose
Animal model for disease-modifying therapies in Parkinson's disease	Animal model for disease-modifying therapies in Parkinson's disease	Animal model for disease-modifying therapies in Parkinson's disease	第61回日本神経学会学術大会 (シンポジウム）	第61回日本神経学会学術大会 (シンポジウム）	2020/09/01	English	Symposium workshop panel(nominated)	Disclose to all
パーキンソン病の前駆期症状を呈するマウスモデルの開発	パーキンソン病の前駆期症状を呈するマウスモデルの開発		日本自律神経学会	日本自律神経学会	2019/11/02			Disclose to all
Prodromal PD mice model	Prodromal PD mice model		Neuro2019 (Symposium)	Neuro2019 (Symposium)	2019/07/27	English	Symposium workshop panel(public)	Disclose to all
α-シヌクレイン凝集抑制治療は、疾患修飾治療になりうるか？	α-シヌクレイン凝集抑制治療は、疾患修飾治療になりうるか？		MDSJ 2019 (Controversy)	MDSJ 2019 (Controversy)	2019/07/26			Disclose to all
Prodromal PDの動物モデル	Prodromal PDの動物モデル		MDSJ (Symposium)	MDSJ (Symposium)	2018/07/06			Disclose to all
Title language:

External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)

Type	Position	Title(Japanese)	Title(English)	Period
若手研究(B)	Representative	新しいシヌクレイン遺伝子導入マウスを用いたパーキンソン病発症メカニズムの解明	Investigation of pathomechanism of Parkinson's disease using novel alpha-synuclein-based genetic mice model	2012-2014
若手研究(B)	Representative	iPS細胞を用いた孤発性パーキンソン病の病態解明と標的分子の同定	Investigation of pathomechanism and identification of therapeutic target of Parkinson's disease using iPS cells	2014-2016
基盤研究(C)	Representative	多系統萎縮症の病態解明と治療法の開発		2016-2019
基盤B	Representative	パーキンソン病関連疾患のモデル作製と治療薬開発		2020/04/01-2023/03/31

Faculty management (title, position)

Title	Period
動物実験施設運営委員会	2013/04/01-2014/03/31
外来医長・看護師長会議委員	2014/04/01-

山門 穂高

山門穂高