石井 輝

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Name(Kanji/Kana/Abecedarium Latinum)
石井 輝/イシイ アキラ/Ishii, Akira
Primary Affiliation(Org1/Job title)
Kyoto University Hospital/Assistant Professor
Contact Address
Type Address(Japanese) Address(English)
Office 〒606-8507京都市左京区聖護院川原町54 54 Shogoin Kawahara-cho, Sakyo, Kyoto, 6068507, Japan
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
日本内科学会 The Japanese Society of Internal Medicine
日本腎臓学会 Japanese Society of Nephrology
日本糖尿病学会 The Japan Diabetes Society
日本透析医学会 The Japanese Society for Dialysis Therapy
日本高血圧学会 The Japanese Society of Hypertension
日本内分泌学会 The Japan Endocrine Society
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 京都大学
researchmap URL
https://researchmap.jp/7000016557
Research Topics
(Japanese)
糖尿病, 肥満, エネルギー代謝にかかわる分泌蛋白、液性因子の腎臓病進展における意義の研究、稀少遺伝性腎疾患の診断についての研究、慢性腎臓病教育入院の効果についての研究
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Ishii A, Katsuura G, Imamaki H, Kimura H, Mori KP, Kuwabara T, Kasahara M, Yokoi H, Ohinata K, Kawanishi T, Tsuchida J, Nakamoto Y, Nakao K, Yanagita M, Mukoyama M, Mori K Ishii A, Katsuura G, Imamaki H, Kimura H, Mori KP, Kuwabara T, Kasahara M, Yokoi H, Ohinata K, Kawanishi T, Tsuchida J, Nakamoto Y, Nakao K, Yanagita M, Mukoyama M, Mori K Ishii A, Katsuura G, Imamaki H, Kimura H, Mori KP, Kuwabara T, Kasahara M, Yokoi H, Ohinata K, Kawanishi T, Tsuchida J, Nakamoto Y, Nakao K, Yanagita M, Mukoyama M, Mori K Obesity-promoting and anti-thermogenic effects of neutrophil gelatinase-associated lipocalin in mice. Obesity-promoting and anti-thermogenic effects of neutrophil gelatinase-associated lipocalin in mice. Obesity-promoting and anti-thermogenic effects of neutrophil gelatinase-associated lipocalin in mice. Scientific Reports, 7, 15501 Scientific Reports, 7, 15501 Scientific Reports, 7, 15501 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Toda N, Mori K, Kasahara M, Koga K, Ishii A, Mori KP, Osaki K, Mukoyama M, Yanagita M, Yokoi H Toda N, Mori K, Kasahara M, Koga K, Ishii A, Mori KP, Osaki K, Mukoyama M, Yanagita M, Yokoi H Toda N, Mori K, Kasahara M, Koga K, Ishii A, Mori KP, Osaki K, Mukoyama M, Yanagita M, Yokoi H Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation. Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation. Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation. Nephrol Dial Transplant Nephrol Dial Transplant Nephrol Dial Transplant 2017/11 Refereed English Research paper(scientific journal) Disclose to all
Kato Y, Mori K, Kasahara M, Osaki K, Ishii A, Mori KP, Toda N, Ohno S, Kuwabara T, Tokudome T, Kishimoto I, Saleem MA, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Kato Y, Mori K, Kasahara M, Osaki K, Ishii A, Mori KP, Toda N, Ohno S, Kuwabara T, Tokudome T, Kishimoto I, Saleem MA, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Kato Y, Mori K, Kasahara M, Osaki K, Ishii A, Mori KP, Toda N, Ohno S, Kuwabara T, Tokudome T, Kishimoto I, Saleem MA, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition. Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition. Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition. Scientific reports, 7, 46624 Scientific reports, 7, 46624 Scientific reports, 7, 46624 2017/04 Refereed Research paper(scientific journal) Disclose to all
Toda N, Mori K, Kasahara M, Ishii A, Koga K, Ohno S, Mori KP, Kato Y, Osaki K, Kuwabara T, Kojima K, Taura D, Sone M, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Toda N, Mori K, Kasahara M, Ishii A, Koga K, Ohno S, Mori KP, Kato Y, Osaki K, Kuwabara T, Kojima K, Taura D, Sone M, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Toda N, Mori K, Kasahara M, Ishii A, Koga K, Ohno S, Mori KP, Kato Y, Osaki K, Kuwabara T, Kojima K, Taura D, Sone M, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis. Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis. Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis. Scientific reports, 7, 42114 Scientific reports, 7, 42114 Scientific reports, 7, 42114 2017/02 Refereed Disclose to all
Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy. Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy. Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy. Journal of the American Society of Nephrology : JASN Journal of the American Society of Nephrology : JASN Journal of the American Society of Nephrology : JASN 2016/07 Refereed Disclose to all
Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Scientific reports, 6, 27192 Scientific reports, 6, 27192 Scientific reports, 6, 27192 2016/06 Refereed Disclose to all
Koga K, Yokoi H, Mori K, Kasahara M, Kuwabara T, Imamaki H, Ishii A, Mori KP, Kato Y, Ohno S, Toda N, Saleem MA, Sugawara A, Nakao K, Yanagita M, Mukoyama M Koga K, Yokoi H, Mori K, Kasahara M, Kuwabara T, Imamaki H, Ishii A, Mori KP, Kato Y, Ohno S, Toda N, Saleem MA, Sugawara A, Nakao K, Yanagita M, Mukoyama M Koga K, Yokoi H, Mori K, Kasahara M, Kuwabara T, Imamaki H, Ishii A, Mori KP, Kato Y, Ohno S, Toda N, Saleem MA, Sugawara A, Nakao K, Yanagita M, Mukoyama M MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy. MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy. MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy. Diabetologia,58,9,2169-2180, 58, 9, 2169-2180 Diabetologia, 58, 9, 2169-2180 Diabetologia,58,9,2169-2180, 58, 9, 2169-2180 2015/09 Refereed Disclose to all
Imamaki H, Ishii A, Yokoi H, Kasahara M, Kuwabara T, Mori KP, Kato Y, Kuwahara T, Satoh M, Nakatani K, Saito Y, Tomosugi N, Sugawara A, Nakao K, Mukoyama M, Yanagita M, Mori K Imamaki H, Ishii A, Yokoi H, Kasahara M, Kuwabara T, Mori KP, Kato Y, Kuwahara T, Satoh M, Nakatani K, Saito Y, Tomosugi N, Sugawara A, Nakao K, Mukoyama M, Yanagita M, Mori K Imamaki H, Ishii A, Yokoi H, Kasahara M, Kuwabara T, Mori KP, Kato Y, Kuwahara T, Satoh M, Nakatani K, Saito Y, Tomosugi N, Sugawara A, Nakao K, Mukoyama M, Yanagita M, Mori K Low Serum Neutrophil Gelatinase-associated Lipocalin Level as a Marker of Malnutrition in Maintenance Hemodialysis Patients. Low Serum Neutrophil Gelatinase-associated Lipocalin Level as a Marker of Malnutrition in Maintenance Hemodialysis Patients. Low Serum Neutrophil Gelatinase-associated Lipocalin Level as a Marker of Malnutrition in Maintenance Hemodialysis Patients. PloS one,, 10, 7, e0132539 PloS one,, 10, 7, e0132539 PloS one,, 10, 7, e0132539 2015 Refereed Disclose to all
Kuwabara T, Mori K, Kasahara M, Yokoi H, Imamaki H, Ishii A, Koga K, Sugawara A, Yasuno S, Ueshima K, Morikawa T, Konishi Y, Imanishi M, Nishiyama A, Nakao K, Mukoyama M Kuwabara T, Mori K, Kasahara M, Yokoi H, Imamaki H, Ishii A, Koga K, Sugawara A, Yasuno S, Ueshima K, Morikawa T, Konishi Y, Imanishi M, Nishiyama A, Nakao K, Mukoyama M Kuwabara T, Mori K, Kasahara M, Yokoi H, Imamaki H, Ishii A, Koga K, Sugawara A, Yasuno S, Ueshima K, Morikawa T, Konishi Y, Imanishi M, Nishiyama A, Nakao K, Mukoyama M Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases. Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases. Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases. PloS one, 9, 2, e88942 PloS one, 9, 2, e88942 PloS one, 9, 2, e88942 2014 Refereed Disclose to all
T. Kuwabara; K. Mori; M. Mukoyama; M. Kasahara; H. Yokoi; Y. Saito; Y. Ogawa; H. Imamaki; T. Kawanishi; A. Ishii; K. Koga; K.P. Mori; Y. Kato; A. Sugawara; K. Nakao T. Kuwabara; K. Mori; M. Mukoyama; M. Kasahara; H. Yokoi; Y. Saito; Y. Ogawa; H. Imamaki; T. Kawanishi; A. Ishii; K. Koga; K.P. Mori; Y. Kato; A. Sugawara; K. Nakao T. Kuwabara; K. Mori; M. Mukoyama; M. Kasahara; H. Yokoi; Y. Saito; Y. Ogawa; H. Imamaki; T. Kawanishi; A. Ishii; K. Koga; K.P. Mori; Y. Kato; A. Sugawara; K. Nakao Exacerbation of diabetic nephropathy by Hyperlipidaemia is mediated by Toll-like receptor 4 in mice Exacerbation of diabetic nephropathy by Hyperlipidaemia is mediated by Toll-like receptor 4 in mice Exacerbation of diabetic nephropathy by Hyperlipidaemia is mediated by Toll-like receptor 4 in mice Diabetologia, 55, 8, 2256-2266 Diabetologia, 55, 8, 2256-2266 Diabetologia, 55, 8, 2256-2266 2012/08 Refereed Disclose to all
H. Yokoi; M. Kasahara; K. Mori; Y. Ogawa; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; Y. Kato; K.P. Mori; N. Toda; S. Ohno; H. Muramatsu; T. Muramatsu; A. Sugawara; M. Mukoyama; K. Nakao H. Yokoi; M. Kasahara; K. Mori; Y. Ogawa; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; Y. Kato; K.P. Mori; N. Toda; S. Ohno; H. Muramatsu; T. Muramatsu; A. Sugawara; M. Mukoyama; K. Nakao H. Yokoi; M. Kasahara; K. Mori; Y. Ogawa; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; Y. Kato; K.P. Mori; N. Toda; S. Ohno; H. Muramatsu; T. Muramatsu; A. Sugawara; M. Mukoyama; K. Nakao Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis Kidney International, 81, 2, 160-169 Kidney International, 81, 2, 160-169 Kidney International, 81, 2, 160-169 2012/01 Refereed Disclose to all
Y. Ogawa; M. Mukoyama; H. Yokoi; M. Kasahara; K. Mori; Y. Kato; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; T. Tokudome; I. Kishimoto; A. Sugawara; K. Nakao Y. Ogawa; M. Mukoyama; H. Yokoi; M. Kasahara; K. Mori; Y. Kato; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; T. Tokudome; I. Kishimoto; A. Sugawara; K. Nakao Y. Ogawa; M. Mukoyama; H. Yokoi; M. Kasahara; K. Mori; Y. Kato; T. Kuwabara; H. Imamaki; T. Kawanishi; K. Koga; A. Ishii; T. Tokudome; I. Kishimoto; A. Sugawara; K. Nakao Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury Journal of the American Society of Nephrology, 23, 7, 1198-1209 Journal of the American Society of Nephrology, 23, 7, 1198-1209 Journal of the American Society of Nephrology, 23, 7, 1198-1209 2012 Refereed Disclose to all

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Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
肥満、エネルギー消費における鉄輸送蛋白 neutrophil gelatinase-associated lipocalin(NGAL)の意義 肥満、エネルギー消費における鉄輸送蛋白 neutrophil gelatinase-associated lipocalin(NGAL)の意義 第48回日本心脈管作動物質学会  第48回日本心脈管作動物質学会  2019/02 Japanese Symposium workshop panel(nominated) Disclose to all
Circulating NGAL accelerates diet-induced obesity through local inhibition of thermogenic beta3 adrenergic nerve/brown adipose tissue axis. Circulating NGAL accelerates diet-induced obesity through local inhibition of thermogenic beta3 adrenergic nerve/brown adipose tissue axis. Circulating NGAL accelerates diet-induced obesity through local inhibition of thermogenic beta3 adrenergic nerve/brown adipose tissue axis. the 18th World Congress of Basic and Clinical Pharmacology (WCP2018) the 18th World Congress of Basic and Clinical Pharmacology (WCP2018) the 18th World Congress of Basic and Clinical Pharmacology (WCP2018) 2018/07 English Oral presentation(general) Disclose to all
Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
石井 輝、横井秀基、柳田素子 石井 輝、横井秀基、柳田素子 腎保護的介入に貢献するマーカーの経済的動向―今後の治療戦略を占う 腎保護的介入に貢献するマーカーの経済的動向―今後の治療戦略を占う 腎臓内科・泌尿器科 8 (6): 577-581, 2018 腎臓内科・泌尿器科 8 (6): 577-581, 2018 2018/12 Joint Work Disclose to all
石井 輝、中田紘介、横井秀基、柳田素子 石井 輝、中田紘介、横井秀基、柳田素子 慢性尿細管間質性腎炎 慢性尿細管間質性腎炎 私の治療 2017-2018年度版, 日本医事新報社, pp525-526, 2017 私の治療 2017-2018年度版, 日本医事新報社, pp525-526, 2017 2017/04 Joint Work Disclose to all
石井 輝、横井秀基、森 潔、森 慶太、古賀健一、柳田素子 石井 輝、横井秀基、森 潔、森 慶太、古賀健一、柳田素子 糖尿病腎症は糸球体or尿細管障害のどちらから始まるか? 糖尿病腎症は糸球体or尿細管障害のどちらから始まるか? 内分泌・糖尿病・代謝内科 44 (3): 215-221, 2017 内分泌・糖尿病・代謝内科 44 (3): 215-221, 2017 2017/03 Joint Work Disclose to all
石井 輝、森 慶太、柳田素子、森 潔 石井 輝、森 慶太、柳田素子、森 潔 尿中NGALの由来・有用性・生物学的作用 尿中NGALの由来・有用性・生物学的作用 生体の科学 67: 404-405、2016 生体の科学 67: 404-405、2016 2016/10 Joint Work Disclose to all
石井 輝、向山政志 石井 輝、向山政志 レニン・アンジオテンシン・アルドステロン系 レニン・アンジオテンシン・アルドステロン系 日本臨牀(増刊号) 最新肥満症学 日本臨牀社, pp139-144, 2014 日本臨牀(増刊号) 最新肥満症学 日本臨牀社, pp139-144, 2014 2014 Joint Work Disclose to all
石井 輝、桒原孝成、笠原正登 石井 輝、桒原孝成、笠原正登 スタチン スタチン 月刊糖尿病 5(11): 80-87, 2013 月刊糖尿病 5(11): 80-87, 2013 2013/11 Joint Work Disclose to all
石井 輝、向山政志、森 潔、横井秀基、桒原孝成、中尾一和 石井 輝、向山政志、森 潔、横井秀基、桒原孝成、中尾一和 ナトリウム利尿ペプチド ナトリウム利尿ペプチド 内分泌・糖尿病・代謝内科 35 (5): 437-442, 2012 内分泌・糖尿病・代謝内科 35 (5): 437-442, 2012 2012/11 Joint Work Disclose to all
石井 輝、小出達真、笠原正登 石井 輝、小出達真、笠原正登 利尿薬と電解質異常 利尿薬と電解質異常 月刊循環器 2(9): 24-32, 2012 月刊循環器 2(9): 24-32, 2012 2012/09 Joint Work Disclose to all
Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
学術奨励賞 日本鉄バイオサイエンス学会 2017/09/24
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
若手研究 Representative 高脂肪、高蛋白食及び高食塩食による糖尿病性腎症進展への影響に対するCTGFの意義 2018/04/01-2020/03/31
若手研究 Representative 高脂肪、高蛋白食及び高食塩食による糖尿病性腎症進展への影響に対するCTGFの意義 (平成30年度分) 2018/04/01-2019/03/31
External funds: other than those above
System Main person Title(Japanese) Title(English) Period
若手研究 石井 輝 高塩、高脂肪、高蛋白食による糖尿病性腎臓病進展にニコチンが及ぼす作用の解明 2019/04/01-2022/03/31