下條 博美

Last Update: 2019/09/25 20:43:48

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Name(Kanji/Kana/Abecedarium Latinum)
下條 博美/シモジョウ ヒロミ/Shimojo, Hiromi
Primary Affiliation(Org1/Job title)
Institute for Frontier Life and Medical Sciences/Program-Specific Assistant Professor
Contact Address
Type Address(Japanese) Address(English)
Office
Phone
Type Number
Office
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 京都大学
researchmap URL
https://researchmap.jp/7000009419
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Kageyama R., Shimojo H. and Ohtsuka T. Kageyama R., Shimojo H. and Ohtsuka T. Dynamic control of neural stem cells by bHLH factors Dynamic control of neural stem cells by bHLH factors Dynamic control of neural stem cells by bHLH factors Neuroscience Research, 138, 12-18 Neuroscience Research, 138, 12-18 Neuroscience Research, 138, 12-18 2019 Refereed Disclose to all
Kageyama R, Shimojo H, Isomura A Kageyama R, Shimojo H, Isomura A Kageyama R, Shimojo H, Isomura A Oscillatory Control of Notch Signaling in Development. Oscillatory Control of Notch Signaling in Development. Oscillatory Control of Notch Signaling in Development. Advances in experimental medicine and biology, 1066, 265-277 Advances in experimental medicine and biology, 1066, 265-277 Advances in experimental medicine and biology, 1066, 265-277 2018 Refereed Disclose to all
Perron A, Nishikawa Y, Iwata J, Shimojo H, Takaya J, Kobayashi K, Imayoshi I, Mbenza NM, Takenoya M, Kageyama R, Kodama Y and Uesugi M. Perron A, Nishikawa Y, Iwata J, Shimojo H, Takaya J, Kobayashi K, Imayoshi I, Mbenza NM, Takenoya M, Kageyama R, Kodama Y and Uesugi M. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. Journal of Biological Chemistry, 293, 21, 8285-8294 Journal of Biological Chemistry, 293, 21, 8285-8294 Journal of Biological Chemistry, 293, 21, 8285-8294 2018 Refereed Disclose to all
Shimojo H, Kageyama R. Shimojo H, Kageyama R. Shimojo H, Kageyama R. Ultradian oscillations in Notch signaling during tissue morphogenesis. Ultradian oscillations in Notch signaling during tissue morphogenesis. Ultradian oscillations in Notch signaling during tissue morphogenesis. Biological Clocks, 79-92 Biological Clocks, 79-92 Biological Clocks, 79-92 2017 Refereed English Research paper(research society, symposium materials, etc.) Disclose to all
Shimojo H, Kageyama R Shimojo H, Kageyama R Shimojo H, Kageyama R Making Waves toward the Shore by Synchronicity. Making Waves toward the Shore by Synchronicity. Making Waves toward the Shore by Synchronicity. Developmental cell, 36, 4, 358-359 Developmental cell, 36, 4, 358-359 Developmental cell, 36, 4, 358-359 2016/02 Refereed Disclose to all
Shimojo H, Kageyama R Shimojo H, Kageyama R Shimojo H, Kageyama R Oscillatory control of Delta-like1 in somitogenesis and neurogenesis: A unified model for different oscillatory dynamics. Oscillatory control of Delta-like1 in somitogenesis and neurogenesis: A unified model for different oscillatory dynamics. Oscillatory control of Delta-like1 in somitogenesis and neurogenesis: A unified model for different oscillatory dynamics. Seminars in cell & developmental biology, 49, 76-82 Seminars in cell & developmental biology, 49, 76-82 Seminars in cell & developmental biology, 49, 76-82 2016/01 Refereed Disclose to all
Shimojo H, Isomura A, Ohtsuka T, Kori H, Miyachi H, Kageyama R Shimojo H, Isomura A, Ohtsuka T, Kori H, Miyachi H, Kageyama R Shimojo H, Isomura A, Ohtsuka T, Kori H, Miyachi H, Kageyama R Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Genes & development, 30, 1, 102-116 Genes & development, 30, 1, 102-116 Genes & development, 30, 1, 102-116 2016/01 Refereed Disclose to all
Kageyama R, Shimojo H, Imayoshi I Kageyama R, Shimojo H, Imayoshi I Kageyama R, Shimojo H, Imayoshi I Dynamic expression and roles of Hes factors in neural development. Dynamic expression and roles of Hes factors in neural development. Dynamic expression and roles of Hes factors in neural development. Cell and tissue research, 359, 1, 125-133 Cell and tissue research, 359, 1, 125-133 Cell and tissue research, 359, 1, 125-133 2015/01 Refereed Disclose to all
Harima Y, Imayoshi I, Shimojo H, Kobayashi T, Kageyama R Harima Y, Imayoshi I, Shimojo H, Kobayashi T, Kageyama R Harima Y, Imayoshi I, Shimojo H, Kobayashi T, Kageyama R The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes. The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes. The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes. Seminars in cell & developmental biology, 34, 85-90 Seminars in cell & developmental biology, 34, 85-90 Seminars in cell & developmental biology, 34, 85-90 2014/10 Refereed Disclose to all
Shimojo H, Harima Y, Kageyama R Shimojo H, Harima Y, Kageyama R Shimojo H, Harima Y, Kageyama R Visualization of Notch signaling oscillation in cells and tissues. Visualization of Notch signaling oscillation in cells and tissues. Visualization of Notch signaling oscillation in cells and tissues. Methods in molecular biology (Clifton, N.J.), 1187, 169-179 Methods in molecular biology (Clifton, N.J.), 1187, 169-179 Methods in molecular biology (Clifton, N.J.), 1187, 169-179 2014 Refereed Disclose to all
I. Imayoshi; H. Shimojo; M. Sakamoto; T. Ohtsuka; R. Kageyama I. Imayoshi; H. Shimojo; M. Sakamoto; T. Ohtsuka; R. Kageyama I. Imayoshi; H. Shimojo; M. Sakamoto; T. Ohtsuka; R. Kageyama Genetic visualization of notch signaling in mammalian neurogenesis Genetic visualization of notch signaling in mammalian neurogenesis Genetic visualization of notch signaling in mammalian neurogenesis Cellular and Molecular Life Sciences, 70, 12, 2045-2057 Cellular and Molecular Life Sciences, 70, 12, 2045-2057 Cellular and Molecular Life Sciences, 70, 12, 2045-2057 2013/06 Refereed English Disclose to all
Kageyama R., Shimojo H., Ohtsuka T., Imayoshi I. Kageyama R., Shimojo H., Ohtsuka T., Imayoshi I. Kageyama R., Shimojo H., Ohtsuka T., Imayoshi I. Maintenance of neural stem cells in the brain: role of Notch signaling. Stem Cells and Cancer Stem Cells Maintenance of neural stem cells in the brain: role of Notch signaling. Stem Cells and Cancer Stem Cells Maintenance of neural stem cells in the brain: role of Notch signaling. Stem Cells and Cancer Stem Cells Therapeutic Applications in Disease and Injury. Vol.4. (Ed. M.A.Hayat) Springer, 2012 Therapeutic Applications in Disease and Injury. Vol.4. (Ed. M.A.Hayat) Springer, 2012 Therapeutic Applications in Disease and Injury. Vol.4. (Ed. M.A.Hayat) Springer, 2012 2012 Refereed English Disclose to all
T. Ohtsuka; H. Shimojo; M. Matsunaga; N. Watanabe; K. Kometani; N. Minato; R. Kageyama T. Ohtsuka; H. Shimojo; M. Matsunaga; N. Watanabe; K. Kometani; N. Minato; R. Kageyama T. Ohtsuka; H. Shimojo; M. Matsunaga; N. Watanabe; K. Kometani; N. Minato; R. Kageyama Gene expression profiling of neural stem cells and identification of regulators of neural differentiation during cortical development Gene expression profiling of neural stem cells and identification of regulators of neural differentiation during cortical development Gene expression profiling of neural stem cells and identification of regulators of neural differentiation during cortical development Stem Cells, 29, 11, 1817-1828 Stem Cells, 29, 11, 1817-1828 Stem Cells, 29, 11, 1817-1828 2011/11 Refereed English Disclose to all
Y. Niwa; H. Shimojo; A. Isomura; A. González; H. Miyachi; R. Kageyama Y. Niwa; H. Shimojo; A. Isomura; A. González; H. Miyachi; R. Kageyama Y. Niwa; H. Shimojo; A. Isomura; A. González; H. Miyachi; R. Kageyama Different types of oscillations in notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis Different types of oscillations in notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis Different types of oscillations in notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis Genes and Development, 25, 11, 1115-1120 Genes and Development, 25, 11, 1115-1120 Genes and Development, 25, 11, 1115-1120 2011/06/01 Refereed English Disclose to all
H. Shimojo; T. Ohtsuka; R. Kageyama H. Shimojo; T. Ohtsuka; R. Kageyama H. Shimojo; T. Ohtsuka; R. Kageyama Dynamic expression of Notch signaling genes in neural stem/ progenitor cells Dynamic expression of Notch signaling genes in neural stem/ progenitor cells Dynamic expression of Notch signaling genes in neural stem/ progenitor cells Frontiers in Neuroscience, 5, JUN, 78 Frontiers in Neuroscience, 5, JUN, 78 Frontiers in Neuroscience, 5, JUN, 78 2011 Refereed English Disclose to all
R. Kageyama; Y. Niwa; H. Shimojo; T. Kobayashi; T. Ohtsuka R. Kageyama; Y. Niwa; H. Shimojo; T. Kobayashi; T. Ohtsuka R. Kageyama; Y. Niwa; H. Shimojo; T. Kobayashi; T. Ohtsuka Ultradian oscillations in Notch signaling regulate dynamic biological events Ultradian oscillations in Notch signaling regulate dynamic biological events Ultradian oscillations in Notch signaling regulate dynamic biological events Current Topics in Developmental Biology, 92, 311-331 Current Topics in Developmental Biology, 92, 311-331 Current Topics in Developmental Biology, 92, 311-331 2010 Refereed English Disclose to all
Kageyama R, Niwa Y, Shimojo H Kageyama R, Niwa Y, Shimojo H Kageyama R, Niwa Y, Shimojo H Developmental timing and oscillating gene expression Developmental timing and oscillating gene expression Developmental timing and oscillating gene expression McGraw-Hill 2010 YearBook of Science & Technology, pp 102- 104. 2010 McGraw-Hill 2010 YearBook of Science & Technology, pp 102- 104. 2010 McGraw-Hill 2010 YearBook of Science & Technology, pp 102- 104. 2010 2010 Refereed English Disclose to all
R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi Dynamic regulation of Notch signaling in neural progenitor cells Dynamic regulation of Notch signaling in neural progenitor cells Dynamic regulation of Notch signaling in neural progenitor cells Current Opinion in Cell Biology, 21, 6, 733-740 Current Opinion in Cell Biology, 21, 6, 733-740 Current Opinion in Cell Biology, 21, 6, 733-740 2009/12 Refereed English Disclose to all
R. Kageyama; Y. Niwa; H. Shimojo R. Kageyama; Y. Niwa; H. Shimojo R. Kageyama; Y. Niwa; H. Shimojo Rhythmic gene expression in somite formation and neural development Rhythmic gene expression in somite formation and neural development Rhythmic gene expression in somite formation and neural development Molecules and Cells, 27, 5, 497-502 Molecules and Cells, 27, 5, 497-502 Molecules and Cells, 27, 5, 497-502 2009/05 Refereed English Disclose to all
R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi R. Kageyama; T. Ohtsuka; H. Shimojo; I. Imayoshi Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition Nature Neuroscience, 11, 11, 1247-1251 Nature Neuroscience, 11, 11, 1247-1251 Nature Neuroscience, 11, 11, 1247-1251 2008/11 Refereed English Disclose to all
H. Shimojo; T. Ohtsuka; R. Kageyama H. Shimojo; T. Ohtsuka; R. Kageyama H. Shimojo; T. Ohtsuka; R. Kageyama Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors Neuron, 58, 1, 52-64 Neuron, 58, 1, 52-64 Neuron, 58, 1, 52-64 2008/04/10 Refereed English Disclose to all
下條博美 下條博美 神経幹細胞の未分化性をNotch シグナルのつくるリズムが維持 神経幹細胞の未分化性をNotch シグナルのつくるリズムが維持 Medical Bio, 5: 12-13. 2008 Medical Bio, 5: 12-13. 2008 2008 Refereed Japanese Disclose to all
T. Ohtsuka; I. Imayoshi; H. Shimojo; E. Nishi; R. Kageyama; S.K. McConnell T. Ohtsuka; I. Imayoshi; H. Shimojo; E. Nishi; R. Kageyama; S.K. McConnell T. Ohtsuka; I. Imayoshi; H. Shimojo; E. Nishi; R. Kageyama; S.K. McConnell Visualization of embryonic neural stem cells using Hes promoters in transgenic mice Visualization of embryonic neural stem cells using Hes promoters in transgenic mice Visualization of embryonic neural stem cells using Hes promoters in transgenic mice Molecular and Cellular Neuroscience, 31, 1, 109-122 Molecular and Cellular Neuroscience, 31, 1, 109-122 Molecular and Cellular Neuroscience, 31, 1, 109-122 2006/01 Refereed English Disclose to all
下條博美 下條博美 Notch シグナル系の発現振動が神経㈲駆細胞の維持を制御 Notch シグナル系の発現振動が神経㈲駆細胞の維持を制御 医学研究科 医学研究科 Refereed Japanese Disclose to all

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Title language:
Misc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
下條博美, 影山龍一郎, 影山龍一郎 下條博美, 影山龍一郎, 影山龍一郎 下條博美, 影山龍一郎, 影山龍一郎 発見から100余年 Notchシグナルの新世紀 形態形成を司るNotchリズム 発見から100余年 Notchシグナルの新世紀 形態形成を司るNotchリズム 発見から100余年 Notchシグナルの新世紀 形態形成を司るNotchリズム 実験医学, 34, 3, 397-403 実験医学, 34, 3, 397-403 実験医学, 34, 3, 397-403 2016/02/01 Japanese Disclose to all
下條博美 下條博美 下條博美 【発生学・神経科学】神経幹細胞の未分化性をNotchシグナルのつくるリズムが維持 【発生学・神経科学】神経幹細胞の未分化性をNotchシグナルのつくるリズムが維持 【発生学・神経科学】神経幹細胞の未分化性をNotchシグナルのつくるリズムが維持 メディカルバイオ, 5, 4, 12-13 メディカルバイオ, 5, 4, 12-13 メディカルバイオ, 5, 4, 12-13 2008/07/01 Japanese Disclose to all
Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Gene expression dynamics regulating neuronal differentiation 神経分化を制御する遺伝子発現ダイナミクス Gene expression dynamics regulating neuronal differentiation 第92回日本生化学会大会 第92回日本生化学会大会 2019/09/20 Japanese Symposium workshop panel(nominated) Disclose to all
The time delays for gene expression and cell-cell interactions regulate various pattern formations during murine embryogenesis マウス発生過程において遺伝子発現と細胞間コミュニケーションの速度が様々なパターン形成を制御する The time delays for gene expression and cell-cell interactions regulate various pattern formations during murine embryogenesis 日本遺伝学会第91回大会 日本遺伝学会第91回大会 2019/09/13 Japanese Symposium workshop panel(nominated) Disclose to all
Oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis Oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis Oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis 第52回日本発生生物学会大会 第52回日本発生生物学会大会 2019/05/17 English Symposium workshop panel(nominated) Disclose to all
Dynamic gene expressions during mammalian neural development Dynamic gene expressions during mammalian neural development Dynamic gene expressions during mammalian neural development 2018 Korea-Japan Joint Symposium on Neurodevelopment 2018 Korea-Japan Joint Symposium on Neurodevelopment 2018 Korea-Japan Joint Symposium on Neurodevelopment 2018/06 Symposium workshop panel(nominated) Disclose to all
Dynamic gene expressions during neural development Dynamic gene expressions during neural development Dynamic gene expressions during neural development 22nd Biennial Meeting of the International Society for Developmental Neuroscience 22nd Biennial Meeting of the International Society for Developmental Neuroscience 22nd Biennial Meeting of the International Society for Developmental Neuroscience 2018/05 Symposium workshop panel(public) Disclose to all
遺伝子発現動態と神経分化の時間制御機構 遺伝子発現動態と神経分化の時間制御機構 次世代脳プロジェクト 冬のシンポジウム2017 次世代脳プロジェクト 冬のシンポジウム2017 2017/12 Symposium workshop panel(nominated) Disclose to all
Ultradian oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis. Ultradian oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis. Ultradian oscillations of Notch signaling in cell-cell interactions regulate dynamic gene expression networks and tissue morphogenesis. 第50回日本発生生物学会 第50回日本発生生物学会 2017/05 Symposium workshop panel(nominated) Disclose to all
Notch signaling dynamics during murine morphogenesis. Notch signaling dynamics during murine morphogenesis. Notch signaling dynamics during murine morphogenesis. 第39回日本分子生物学会年会 第39回日本分子生物学会年会 2016/12 Symposium workshop panel(nominated) Disclose to all
Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Sapporo Symposium on Biological Rhythm in 2016 Sapporo Symposium on Biological Rhythm in 2016 2016/11 Symposium workshop panel(nominated) Disclose to all
Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. 第89回日本生化学会大会 第89回日本生化学会大会 2016/09 Symposium workshop panel(nominated) Disclose to all
Dynamic expression of Notch ligand Dll1 during development Dynamic expression of Notch ligand Dll1 during development Dynamic expression of Notch ligand Dll1 during development 第38回日本分子生物学会年会/第88回日本生化学会大会 合同大会 第38回日本分子生物学会年会/第88回日本生化学会大会 合同大会 2015/12 Symposium workshop panel(nominated) Disclose to all
Dynamic expression of Notch ligand Dll1 during development Dynamic expression of Notch ligand Dll1 during development Dynamic expression of Notch ligand Dll1 during development 第120回日本解剖学会総会・全国学術集会/第92回日本生理学会大会 合同大会 第120回日本解剖学会総会・全国学術集会/第92回日本生理学会大会 合同大会 2014 Symposium workshop panel(nominated) Disclose to all
The significance of dynamic proneural gene expression in neural development The significance of dynamic proneural gene expression in neural development The significance of dynamic proneural gene expression in neural development 第36回日本分子生物学会年会 第36回日本分子生物学会年会 2013/12 Symposium workshop panel(nominated) Disclose to all

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Title language:
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
若手研究(B) Representative 神経発生における遺伝子発現モードによる神経分化制御機構の解明 2012-2014
新学術領域研究(研究領域提案型) Representative 細胞集団制御における隣接細胞間シグナル伝達速度の意義 2012-2013
若手研究(B) Representative 神経発生における遺伝子発現モードによる神経分化制御機構の解明 (平成26年度分) 2014/04/01-2015/03/31
基盤研究(C) Representative 細胞運命決定のタイミングを制御する分子タイマーの実体と時間制御機構 2018/04/01-2021/03/31
基盤研究(C) Representative 細胞運命決定のタイミングを制御する分子タイマーの実体と時間制御機構 (平成30年度分) 2018/04/01-2019/03/31