斎藤 通紀

Last Update: 2015/07/10 13:14:43

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Name(Kanji/Kana/Abecedarium Latinum)
斎藤 通紀/サイトウ ミチノリ/Saitou, Mitinori
Primary Affiliation(Org1/Job title)
Institute for Advanced Study/Professor
Faculty
Org1 Job title
医学部
Concurrent Affiliation
Org1 Job title
物質-細胞統合システム拠点 連携主任研究者
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 京都大学
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
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researchmap URL
https://researchmap.jp/7000008794
Research Topics
(Japanese)
生殖細胞の発生・増殖・分化・成熟機構とその再構成、エピゲノム再編成の分子機構、微量エピゲノム解析法の開発、幹細胞の増殖制御機構とその応用
Fields of research (key words)
Key words(Japanese) Key words(English)
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Saitou, M., Kagiwada, S., and Kurimoto, K. Saitou, M., Kagiwada, S., and Kurimoto, K. Saitou, M., Kagiwada, S., and Kurimoto, K. Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development, 139, 15-31, (2012). Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development, 139, 15-31, (2012). Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development, 139, 15-31, (2012). 2012 Refereed English Research paper(scientific journal) Disclose to all
Yabuta, Y., Ohta, H., Abe, T., Kurimoro, K., Chuma, S., and Saitou, M. Yabuta, Y., Ohta, H., Abe, T., Kurimoro, K., Chuma, S., and Saitou, M. Yabuta, Y., Ohta, H., Abe, T., Kurimoro, K., Chuma, S., and Saitou, M. TDRD5 is required for retrotransposon silencing, chromatoid body assembly and spermiogenesis in mice. The Journal of Cell Biology, 192, 781-795, (2011). TDRD5 is required for retrotransposon silencing, chromatoid body assembly and spermiogenesis in mice. The Journal of Cell Biology, 192, 781-795, (2011). TDRD5 is required for retrotransposon silencing, chromatoid body assembly and spermiogenesis in mice. The Journal of Cell Biology, 192, 781-795, (2011). 2011 Refereed English Research paper(scientific journal) Disclose to all
Hirota, T., Ohta, H., Shigeta, M., Niwa, H., and Saitou, M. Hirota, T., Ohta, H., Shigeta, M., Niwa, H., and Saitou, M. Hirota, T., Ohta, H., Shigeta, M., Niwa, H., and Saitou, M. Drug-inducible gene recombination by the Dppa3-MER Cre MER transgene in the developmental cycle of the germ cell lineage in mice. Biology of Reproduction, 85, 367-377, (2011) Drug-inducible gene recombination by the Dppa3-MER Cre MER transgene in the developmental cycle of the germ cell lineage in mice. Biology of Reproduction, 85, 367-377, (2011) Drug-inducible gene recombination by the Dppa3-MER Cre MER transgene in the developmental cycle of the germ cell lineage in mice. Biology of Reproduction, 85, 367-377, (2011) 2011 Refereed English Research paper(scientific journal) Disclose to all
Hayashi, K., Ohta, H., Kurimoto, K., Aramaki, S., and Saitou, M. Hayashi, K., Ohta, H., Kurimoto, K., Aramaki, S., and Saitou, M. Hayashi, K., Ohta, H., Kurimoto, K., Aramaki, S., and Saitou, M. Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell, 146, 519-532, (2011). Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell, 146, 519-532, (2011). Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell, 146, 519-532, (2011). 2011 Refereed English Research paper(scientific journal) Disclose to all
Kurimoto, K., and Saitou, M. Kurimoto, K., and Saitou, M. Kurimoto, K., and Saitou, M. Single-cell cDNA microarray profiling of complex biological processes of differentiation. Current Opinion in Genetics and Development, 20, 470-477, (2010). Single-cell cDNA microarray profiling of complex biological processes of differentiation. Current Opinion in Genetics and Development, 20, 470-477, (2010). Single-cell cDNA microarray profiling of complex biological processes of differentiation. Current Opinion in Genetics and Development, 20, 470-477, (2010). 2010 Refereed English Research paper(scientific journal) Disclose to all
Ogushi, S., and Saitou, M. Ogushi, S., and Saitou, M. Ogushi, S., and Saitou, M. The nucleolus in the mouse oocyte is required for the early step of both female and male pronucleus organization. Journal of Reproduction and Development, 56, 495-501, (2010). The nucleolus in the mouse oocyte is required for the early step of both female and male pronucleus organization. Journal of Reproduction and Development, 56, 495-501, (2010). The nucleolus in the mouse oocyte is required for the early step of both female and male pronucleus organization. Journal of Reproduction and Development, 56, 495-501, (2010). 2010 Refereed English Research paper(scientific journal) Disclose to all
Saitou, M., and Yamaji, M. Saitou, M., and Yamaji, M. Saitou, M., and Yamaji, M. Germ cell specification in mice: Signalling, transcription regulation and epigenetic consequences. Reproduction, 139, 931-942, (2010). Germ cell specification in mice: Signalling, transcription regulation and epigenetic consequences. Reproduction, 139, 931-942, (2010). Germ cell specification in mice: Signalling, transcription regulation and epigenetic consequences. Reproduction, 139, 931-942, (2010). 2010 Refereed English Research paper(scientific journal) Disclose to all
Yamaji, M., Tanaka, T., Shigeta, M., Chuma, S., Saga, Y., and Saitou, M. Yamaji, M., Tanaka, T., Shigeta, M., Chuma, S., Saga, Y., and Saitou, M. Yamaji, M., Tanaka, T., Shigeta, M., Chuma, S., Saga, Y., and Saitou, M. Functional reconstruction of Nanos3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of Nanos3. Reproduction, 139, 381-393, (2010). Functional reconstruction of Nanos3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of Nanos3. Reproduction, 139, 381-393, (2010). Functional reconstruction of Nanos3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of Nanos3. Reproduction, 139, 381-393, (2010). 2010 Refereed English Research paper(scientific journal) Disclose to all
Saitou, M. Saitou, M. Saitou, M. Germ cell specification in mice. Current Opinion in Genetics and Development, 19, 386-395, (2009). Germ cell specification in mice. Current Opinion in Genetics and Development, 19, 386-395, (2009). Germ cell specification in mice. Current Opinion in Genetics and Development, 19, 386-395, (2009). 2009 Refereed English Research paper(scientific journal) Disclose to all
Ohinata, Y., Ohta, H., Shigeta, M., Yamanaka, K., Wakayama, T., and Saitou, M. Ohinata, Y., Ohta, H., Shigeta, M., Yamanaka, K., Wakayama, T., and Saitou, M. Ohinata, Y., Ohta, H., Shigeta, M., Yamanaka, K., Wakayama, T., and Saitou, M. A signaling principle for the specification of the germ cell lineage in mice. Cell, 137, 571-584, (2009). A signaling principle for the specification of the germ cell lineage in mice. Cell, 137, 571-584, (2009). A signaling principle for the specification of the germ cell lineage in mice. Cell, 137, 571-584, (2009). 2009 Refereed English Research paper(scientific journal) Disclose to all
Ohinata, Y., Sano, M., Shigeta, M., Yamanaka, K., and Saitou, M. Ohinata, Y., Sano, M., Shigeta, M., Yamanaka, K., and Saitou, M. Ohinata, Y., Sano, M., Shigeta, M., Yamanaka, K., and Saitou, M. A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Blimp1-mVenus and stella-ECFP double transgenic reporter. Reproduction, 136, 503-514, (2008). A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Blimp1-mVenus and stella-ECFP double transgenic reporter. Reproduction, 136, 503-514, (2008). A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Blimp1-mVenus and stella-ECFP double transgenic reporter. Reproduction, 136, 503-514, (2008). 2008 Refereed English Research paper(scientific journal) Disclose to all
Yamaji, M., Seki, Y., Kurimoto, K., Yabuta, Y., Yuasa, M., Shigeta, M., Yamanaka, K., Ohinata, Y., and Saitou, M. Yamaji, M., Seki, Y., Kurimoto, K., Yabuta, Y., Yuasa, M., Shigeta, M., Yamanaka, K., Ohinata, Y., and Saitou, M. Yamaji, M., Seki, Y., Kurimoto, K., Yabuta, Y., Yuasa, M., Shigeta, M., Yamanaka, K., Ohinata, Y., and Saitou, M. Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nature Genetics, 40, 1016-1022, (2008). Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nature Genetics, 40, 1016-1022, (2008). Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nature Genetics, 40, 1016-1022, (2008). 2008 Refereed English Research paper(scientific journal) Disclose to all
Kurimoto, K., Yabuta, Y., Ohinata, Y., Shigeta, M., Yamanaka, K., and Saitou, M. Kurimoto, K., Yabuta, Y., Ohinata, Y., Shigeta, M., Yamanaka, K., and Saitou, M. Kurimoto, K., Yabuta, Y., Ohinata, Y., Shigeta, M., Yamanaka, K., and Saitou, M. Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes & Development, 22, 1617-1635, (2008). Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes & Development, 22, 1617-1635, (2008). Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes & Development, 22, 1617-1635, (2008). 2008 Refereed English Research paper(scientific journal) Disclose to all

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Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
文部科学大臣表彰若手科学者賞
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
若手研究S Representative 多彩な細胞系譜の運命決定・恒常性を制御する転写因子Blimp1の統合的機能解明 -
特定領域研究  Representative 生殖細胞エピゲノム獲得機構の解明とその再構成 -
挑戦的萌芽研究 Assignment 癌転移を制御する骨髄由来の細胞系譜決定 -
特定領域研究 生殖細胞エピゲノム獲得機構の解明とその再構成 2008-2012
若手研究(S) 多彩な細胞系譜の運命決定・恒常性を制御する転写因子Blimp1の統合的機能解明 2009-2013
若手研究(S) 多彩な細胞系譜の運命決定・恒常性を制御する転写因子Blimp1の統合的機能解明 2009-2013
若手研究(S) Representative 多彩な細胞系譜の運命決定・恒常性を制御する転写因子Blimp1の統合的機能解明 2009-2013
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
組織学 後期不定 医学研究科 2011/04-2012/03
医科学研究 Laboratory visit 前期不定 医学研究科 2012/04-2013/03
組織学 Histology 後期不定 医学研究科 2012/04-2013/03
A1a 組織学 Lecture in Histology 後期前半 医学部 2013/04-2014/03
A1b 組織学実習 Practice Course in Histology 後期前半 医学部 2013/04-2014/03
組織学 Histology 後期不定 医学研究科 2013/04-2014/03
A1a 組織学 Histology 後期前半 医学部 2014/04-2015/03
A1b 組織学実習 Laboratory Course in Histology 後期前半 医学部 2014/04-2015/03
組織学 Histology 後期不定 医学研究科 2014/04-2015/03
先端生命科学 Frontier in Life Sciences 通年集中 生命科学研究科 2014/04-2015/03
A1a 組織学 Histology 後期前半 医学部 2015/04-2016/03
A1b 組織学実習 Laboratory Course in Histology 後期前半 医学部 2015/04-2016/03
生物学のフロンティア Frontiers of Biology 前期 全学共通科目 2015/04-2016/03
組織学 Histology 後期不定 医学研究科 2015/04-2016/03

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School management (title, position)
Title Period
経費削減・有効利用プロジェクトチーム-委員 -
全学共通教育システム委員会-委員 -
施設整備委員会 6号委員 2014/10/01-2016/09/30
Faculty management (title, position)
Title Period
解剖センター運営委員会-委員 -
(論文調査委員)選定委員会-委員 -
外国語試問委員会‐委員、委員長 -
遺伝専門小委員会-委員 -
共用試験委員会-委員 -
医学図書館運営委員会-委員 -
国際交流委員会-委員 -
カリキュラム企画委員会-委員 -
研究科運営委員会-委員 -
研究科長(学部長)協力委員 -
医学研究科・医学部放射性同位元素等管理委員会 -
大学評価部局委員会 2012/04/01-2016/03/31
医学研究科・医学部動物実験委員会 2015/04/01-2016/09/30
動物実験施設管理委員会 2015/04/01-2017/03/31
放射性同位元素等管理委員会 -
学務委員会 2014/04/01-2016/03/31
間接経費使途検討委員会 2014/10/01-2016/09/30

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Other activities (public organizations)
Committee(Japanese) Committee(English) Title Organization name Period
文部科学省 特定胚及びES細胞等研究専門委員会(第70回) -
ヒトES細胞等からの生殖細胞作成・利用作業部会(講演) -
平成21年科学技術・学術審議会生命倫理・安全部会による「ヒトES細胞等からの生殖細胞の作成・利用について」の作成 -
平成23年2月8日、科学技術・学術審議会専門委員(生命倫理・安全部会 特定胚及びヒトES細胞等研究専門委員会)に任命 -