二木 史朗

Last Update: 2019/10/16 13:19:21

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Name(Kanji/Kana/Abecedarium Latinum)
二木 史朗/フタキ シロウ/Futaki, Shiroh
Primary Affiliation(Org1/Job title)
Institute for Chemical Research (ICR)/Professor
Affiliated programs (koza)
Org1 Job title
Graduate Schools Pharmaceutical Sciences Professor
Contact Address
Type Address(Japanese) Address(English)
Office 〒611-0011 京都府宇治市五ヶ庄 Gokasho, Uji, Kyoto 611-0011, JAPAN
Phone
Type Number
Office 0774-38-3210
E-mail Address
E-mail address
futaki @ scl.kyoto-u.ac.jp
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
日本薬学会 The Pharmaceutical Society of Japan
日本化学会 The Chemical Society of Japan
日本ペプチド学会 The Japanese Chemical Society
日本生化学会 The Japanese Biochemical Society
近畿化学協会 Kinka Chemical Society
日本ケミカルバイオロジー学会 Japanese Society for Chemical Biology
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
薬学修士 MS 京都大学 Kyoto University
薬学博士 PhD 京都大学 Kyoto University
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
1987/04/01-1993/05/31 徳島大学薬学部 Faculty of Pharmaceutical Scences, The University of Tokushima 助手 Research Associate
1993/06/01-1997/10/30 徳島大学薬学部 Faculty of Pharmaceutical Scences, The University of Tokushima 助教授 Associate Professor
1997/11/01-2005/03/31 京都大学化学研究所 Institute for Chemical Research, Kyoto University 助教授 Associate Professor
2005/04/01- 京都大学化学研究所 Institute for Chemical Research, Kyoto University 教授 Professor
Personal Website(s) (URL(s))
URL
http://www.scl.kyoto-u.ac.jp/‾bfdc/index.html
ORCID ID
https://orcid.org/0000-0002-0124-4002
researchmap URL
https://researchmap.jp/read0170990
Research Topics
(Japanese)
1)細胞機能・遺伝子を制御する生理活性蛋白質の創製 2)ペプチドを基盤とするバイオ高分子の細胞内導入法の開発とその原理 3)生体膜の構造変化を誘起する蛋白質・ペプチドの機能設計 4)人工転写調節蛋白質の設計と遺伝子発現制御 5)膜蛋白質の会合制御とシグナル調節
(English)
1. Creation of bioactive proteins that control cell function and genes 2. Development of peptide-based intracellular delivery systems for biomacromolecules 3. Design of peptides and proteins that induce membrane curvature 4. Design of artificial transcription factors that regulate gene expression 5. Assembly control of membrane proteins and the regulation of biological signals
Fields of research (key words)
Key words(Japanese) Key words(English)
生体機能設計化学 Biofunctional-design Chemistry
ペプチド・タンパク質工学 Peptide/Protein Engineering
細胞ペプチド化学 Cellular Peptide Chemistry
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Futaki S, Matsuzaki K, Goto Y Futaki S, Matsuzaki K, Goto Y Futaki S, Matsuzaki K, Goto Y Meeting Peptides in Kyoto. Meeting Peptides in Kyoto. Meeting Peptides in Kyoto. Chembiochem : a European journal of chemical biology, 20, 16, 2015-2016 Chembiochem : a European journal of chemical biology, 20, 16, 2015-2016 Chembiochem : a European journal of chemical biology, 20, 16, 2015-2016 2019/08 Refereed Disclose to all
Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S Sakai T, Kawano K, Iino M, Takeuchi T, Imanishi M, Futaki S Loosening of Lipid Packing by Cell-Surface Recruitment of Amphiphilic Peptides by Coiled-Coil Tethering. Loosening of Lipid Packing by Cell-Surface Recruitment of Amphiphilic Peptides by Coiled-Coil Tethering. Loosening of Lipid Packing by Cell-Surface Recruitment of Amphiphilic Peptides by Coiled-Coil Tethering. Chembiochem : a European journal of chemical biology, 20, 16, 2151-2159 Chembiochem : a European journal of chemical biology, 20, 16, 2151-2159 Chembiochem : a European journal of chemical biology, 20, 16, 2151-2159 2019/08 Refereed Disclose to all
Kawano K, Ogushi M, Masuda T, Futaki S Kawano K, Ogushi M, Masuda T, Futaki S Kawano K, Ogushi M, Masuda T, Futaki S Development of a membrane curvature-sensing peptide based on a structure-activity correlation study. Development of a membrane curvature-sensing peptide based on a structure-activity correlation study. Development of a membrane curvature-sensing peptide based on a structure-activity correlation study. Chemical & pharmaceutical bulletin Chemical & pharmaceutical bulletin Chemical & pharmaceutical bulletin 2019/07 Refereed Disclose to all
Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Komei Ikegami, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida, Takahiro Seki, Hiroshi Katsuki, Shiroh Futaki, Masaki Otagiri, Toru Maruyama Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Komei Ikegami, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida, Takahiro Seki, Hiroshi Katsuki, Shiroh Futaki, Masaki Otagiri, Toru Maruyama Shota Ichimizu, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Komei Ikegami, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Taro Shimizu, Yu Ishima, Tatsuhiro Ishida, Takahiro Seki, Hiroshi Katsuki, Shiroh Futaki, Masaki Otagiri, Toru Maruyama Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape Journal of Controlled Release, 304, 156-163 Journal of Controlled Release, 304, 156-163 Journal of Controlled Release, 304, 156-163 2019/06/28 Refereed Disclose to all
Akishiba M, Futaki S Akishiba M, Futaki S Akishiba M, Futaki S Inducible Membrane Permeabilization by Attenuated Lytic Peptides: A New Concept for Accessing Cell Interiors through Ruffled Membranes. Inducible Membrane Permeabilization by Attenuated Lytic Peptides: A New Concept for Accessing Cell Interiors through Ruffled Membranes. Inducible Membrane Permeabilization by Attenuated Lytic Peptides: A New Concept for Accessing Cell Interiors through Ruffled Membranes. Molecular pharmaceutics, 16, 6, 2540-2548 Molecular pharmaceutics, 16, 6, 2540-2548 Molecular pharmaceutics, 16, 6, 2540-2548 2019/06 Refereed Disclose to all
Akiko Okuda, Shinya Tahara, Hisaaki Hirose, Toshihide Takeuchi, Ikuhiko Nakase, Atsushi Ono, Masanori Takehashi, Seigo Tanaka, Shiroh Futaki Akiko Okuda, Shinya Tahara, Hisaaki Hirose, Toshihide Takeuchi, Ikuhiko Nakase, Atsushi Ono, Masanori Takehashi, Seigo Tanaka, Shiroh Futaki Akiko Okuda, Shinya Tahara, Hisaaki Hirose, Toshihide Takeuchi, Ikuhiko Nakase, Atsushi Ono, Masanori Takehashi, Seigo Tanaka, Shiroh Futaki Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated Endocytosis Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated Endocytosis Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated Endocytosis Biomacromolecules, 20, 5, 1849-1859 Biomacromolecules, 20, 5, 1849-1859 Biomacromolecules, 20, 5, 1849-1859 2019/05/13 Refereed Disclose to all
Yoshimasa Kawaguchi, Shoko Ise, Yusuke Azuma, Toshihide Takeuchi, Kenichi Kawano, Toan Khanh Le, Junko Ohkanda, Shiroh Futaki Yoshimasa Kawaguchi, Shoko Ise, Yusuke Azuma, Toshihide Takeuchi, Kenichi Kawano, Toan Khanh Le, Junko Ohkanda, Shiroh Futaki Yoshimasa Kawaguchi, Shoko Ise, Yusuke Azuma, Toshihide Takeuchi, Kenichi Kawano, Toan Khanh Le, Junko Ohkanda, Shiroh Futaki Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine Bioconjugate Chemistry, 30, 2, 454-460 Bioconjugate Chemistry, 30, 2, 454-460 Bioconjugate Chemistry, 30, 2, 454-460 2019/02/20 Refereed Disclose to all
Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S Masuda T, Baba K, Nomura T, Tsujita K, Murayama T, Itoh T, Takatani-Nakase T, Sokabe M, Inagaki N, Futaki S An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. Communications biology, 2, 243 Communications biology, 2, 243 Communications biology, 2, 243 2019 Refereed Disclose to all
Noguchi Kosuke, Aoki Ayako, Kobayashi Nahoko Bailey, Takatani-Nakase Tomoka, Yoshida Tetsuhiko, Fujii Ikuo, Futaki Shiroh, Nakase Ikuhiko Noguchi Kosuke, Aoki Ayako, Kobayashi Nahoko Bailey, Takatani-Nakase Tomoka, Yoshida Tetsuhiko, Fujii Ikuo, Futaki Shiroh, Nakase Ikuhiko Noguchi Kosuke, Aoki Ayako, Kobayashi Nahoko Bailey, Takatani-Nakase Tomoka, Yoshida Tetsuhiko, Fujii Ikuo, Futaki Shiroh, Nakase Ikuhiko Arginine-rich cell-penetrating peptide-modified exosomes for macropinocytosis induction and effective cellular uptake Arginine-rich cell-penetrating peptide-modified exosomes for macropinocytosis induction and effective cellular uptake Arginine-rich cell-penetrating peptide-modified exosomes for macropinocytosis induction and effective cellular uptake JOURNAL OF PEPTIDE SCIENCE, 24, S58 JOURNAL OF PEPTIDE SCIENCE, 24, S58 JOURNAL OF PEPTIDE SCIENCE, 24, S58 2018/09 Refereed Disclose to all
Tsuji S, Shinoda K, Futaki S, Imanishi M Tsuji S, Shinoda K, Futaki S, Imanishi M Tsuji S, Shinoda K, Futaki S, Imanishi M Sequence-specific 5mC detection in live cells based on the TALE-split luciferase complementation system. Sequence-specific 5mC detection in live cells based on the TALE-split luciferase complementation system. Sequence-specific 5mC detection in live cells based on the TALE-split luciferase complementation system. The Analyst, 143, 16, 3793-3797 The Analyst, 143, 16, 3793-3797 The Analyst, 143, 16, 3793-3797 2018/08/21 Refereed Disclose to all
Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S Modular Redesign of a Cationic Lytic Peptide to Promote the Endosomal Escape of Biomacromolecules. Modular Redesign of a Cationic Lytic Peptide to Promote the Endosomal Escape of Biomacromolecules. Modular Redesign of a Cationic Lytic Peptide to Promote the Endosomal Escape of Biomacromolecules. Angewandte Chemie (International ed. in English), 57, 39, 12771-12774 Angewandte Chemie (International ed. in English), 57, 39, 12771-12774 Angewandte Chemie (International ed. in English), 57, 39, 12771-12774 2018/08 Refereed Disclose to all
Ryo Hirata, Ayame Torii, Kenichi Kawano, Shiroh Futaki, Ayumi Imayoshi, Kazunori Tsubaki Ryo Hirata, Ayame Torii, Kenichi Kawano, Shiroh Futaki, Ayumi Imayoshi, Kazunori Tsubaki Ryo Hirata, Ayame Torii, Kenichi Kawano, Shiroh Futaki, Ayumi Imayoshi, Kazunori Tsubaki Development of xanthene dyes containing arylacetylenes: The role of acetylene linker and substituents on the aryl group Development of xanthene dyes containing arylacetylenes: The role of acetylene linker and substituents on the aryl group Development of xanthene dyes containing arylacetylenes: The role of acetylene linker and substituents on the aryl group Tetrahedron, 74, 27, 3608-3615 Tetrahedron, 74, 27, 3608-3615 Tetrahedron, 74, 27, 3608-3615 2018/07/05 Refereed Disclose to all
Shota Ichimizu, Hiroshi Watanabe, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Yuka Nakamura, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Ryota Tanaka, Yuki Enoki, Yu Ishima, Akihiko Kuniyasu, Yoshihiro Kobashigawa, Hiroshi Morioka, Shiro Futaki, Masaki Otagiri, Toru Maruyama, Toru Maruyama Shota Ichimizu, Hiroshi Watanabe, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Yuka Nakamura, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Ryota Tanaka, Yuki Enoki, Yu Ishima, Akihiko Kuniyasu, Yoshihiro Kobashigawa, Hiroshi Morioka, Shiro Futaki, Masaki Otagiri, Toru Maruyama, Toru Maruyama Shota Ichimizu, Hiroshi Watanabe, Hiroshi Watanabe, Hitoshi Maeda, Keisuke Hamasaki, Yuka Nakamura, Victor Tuan Giam Chuang, Ryo Kinoshita, Kento Nishida, Ryota Tanaka, Yuki Enoki, Yu Ishima, Akihiko Kuniyasu, Yoshihiro Kobashigawa, Hiroshi Morioka, Shiro Futaki, Masaki Otagiri, Toru Maruyama, Toru Maruyama Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery Journal of Controlled Release, 277, 23-34 Journal of Controlled Release, 277, 23-34 Journal of Controlled Release, 277, 23-34 2018/05/10 Disclose to all
Sakagami Koki, Masuda Toshihiro, Kawano Kenichi, Futaki Shiroh Sakagami Koki, Masuda Toshihiro, Kawano Kenichi, Futaki Shiroh Sakagami Koki, Masuda Toshihiro, Kawano Kenichi, Futaki Shiroh Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides MOLECULAR PHARMACEUTICS, 15, 3, 1332-1340 MOLECULAR PHARMACEUTICS, 15, 3, 1332-1340 MOLECULAR PHARMACEUTICS, 15, 3, 1332-1340 2018/03 Refereed Disclose to all
Kouki Shinoda, Shogo Tsuji, Shiroh Futaki, Miki Imanishi Kouki Shinoda, Shogo Tsuji, Shiroh Futaki, Miki Imanishi Kouki Shinoda, Shogo Tsuji, Shiroh Futaki, Miki Imanishi Nested PUF Proteins: Extending Target RNA Elements for Gene Regulation Nested PUF Proteins: Extending Target RNA Elements for Gene Regulation Nested PUF Proteins: Extending Target RNA Elements for Gene Regulation ChemBioChem, 19, 2, 171-176 ChemBioChem, 19, 2, 171-176 ChemBioChem, 19, 2, 171-176 2018/01/18 Refereed Disclose to all
Akari Yamagami, Kenichi Kawano, Shiroh Futaki, Kouji Kuramochi, Kouji Kuramochi, Kazunori Tsubaki Akari Yamagami, Kenichi Kawano, Shiroh Futaki, Kouji Kuramochi, Kouji Kuramochi, Kazunori Tsubaki Akari Yamagami, Kenichi Kawano, Shiroh Futaki, Kouji Kuramochi, Kouji Kuramochi, Kazunori Tsubaki Syntheses and properties of second-generation V-shaped xanthene dyes with piperidino groups Syntheses and properties of second-generation V-shaped xanthene dyes with piperidino groups Syntheses and properties of second-generation V-shaped xanthene dyes with piperidino groups Tetrahedron, 73, 50, 7061-7066 Tetrahedron, 73, 50, 7061-7066 Tetrahedron, 73, 50, 7061-7066 2017/12/14 Refereed Disclose to all
Backlund Coralie M., Sgolastra Federica, Otter Ronja, Minter Lisa M., Takeuchi Toshihide, Futaki Shiroh, Tew Gregory N. Backlund Coralie M., Sgolastra Federica, Otter Ronja, Minter Lisa M., Takeuchi Toshihide, Futaki Shiroh, Tew Gregory N. Backlund Coralie M., Sgolastra Federica, Otter Ronja, Minter Lisa M., Takeuchi Toshihide, Futaki Shiroh, Tew Gregory N. Increased hydrophobic block length of PTDMs promotes protein internalization (vol 7, pg 7514, 2016) Increased hydrophobic block length of PTDMs promotes protein internalization (vol 7, pg 7514, 2016) Increased hydrophobic block length of PTDMs promotes protein internalization (vol 7, pg 7514, 2016) POLYMER CHEMISTRY, 8, 43, 6688 POLYMER CHEMISTRY, 8, 43, 6688 POLYMER CHEMISTRY, 8, 43, 6688 2017/11/20 Refereed Disclose to all
Shiroh Futaki, Ikuhiko Nakase Shiroh Futaki, Ikuhiko Nakase Shiroh Futaki, Ikuhiko Nakase Cell-Surface Interactions on Arginine-Rich Cell-Penetrating Peptides Allow for Multiplex Modes of Internalization Cell-Surface Interactions on Arginine-Rich Cell-Penetrating Peptides Allow for Multiplex Modes of Internalization Cell-Surface Interactions on Arginine-Rich Cell-Penetrating Peptides Allow for Multiplex Modes of Internalization Accounts of Chemical Research, 50, 10, 2449-2456 Accounts of Chemical Research, 50, 10, 2449-2456 Accounts of Chemical Research, 50, 10, 2449-2456 2017/10/17 Refereed Disclose to all
Gen Tanaka, Yoshimasa Kawaguchi, Keiko Kuwata, Toshihide Takeuchi, Ikuhiko Nakase, Shiroh Futaki Gen Tanaka, Yoshimasa Kawaguchi, Keiko Kuwata, Toshihide Takeuchi, Ikuhiko Nakase, Shiroh Futaki Gen Tanaka, Yoshimasa Kawaguchi, Keiko Kuwata, Toshihide Takeuchi, Ikuhiko Nakase, Shiroh Futaki Photoaffinity labeling methods to explore internalization mechanisms of arginine-rich cell-penetrating peptides Photoaffinity labeling methods to explore internalization mechanisms of arginine-rich cell-penetrating peptides Photoaffinity labeling methods to explore internalization mechanisms of arginine-rich cell-penetrating peptides Photoaffinity Labeling for Structural Probing Within Protein, 225-240 Photoaffinity Labeling for Structural Probing Within Protein, 225-240 Photoaffinity Labeling for Structural Probing Within Protein, 225-240 2017/09/25 Disclose to all
Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund, Shiroh Futaki Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund, Shiroh Futaki Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi, Kentarou Sakamoto, Hao Hsin Yu, Ikuhiko Nakase, Tomoka Takatani-Nakase, Fatemeh Madani, Astrid Gräslund, Shiroh Futaki Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide Nature Chemistry, 9, 751-761 Nature Chemistry, 9, 751-761 Nature Chemistry, 9, 751-761 2017/08/01 Disclose to all
Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Gräslund A, Futaki S Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide. Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide. Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide. Nature chemistry, 9, 8, 751-761 Nature chemistry, 9, 8, 751-761 Nature chemistry, 9, 8, 751-761 2017/08/01 Refereed Disclose to all
Murayama T, Masuda T, Afonin S, Kawano K, Takatani-Nakase T, Ida H, Takahashi Y, Fukuma T, Ulrich AS, Futaki S Murayama T, Masuda T, Afonin S, Kawano K, Takatani-Nakase T, Ida H, Takahashi Y, Fukuma T, Ulrich AS, Futaki S Murayama T, Masuda T, Afonin S, Kawano K, Takatani-Nakase T, Ida H, Takahashi Y, Fukuma T, Ulrich AS, Futaki S Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells. Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells. Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells. Angewandte Chemie (International ed. in English), 56, 26, 7644-7647 Angewandte Chemie (International ed. in English), 56, 26, 7644-7647 Angewandte Chemie (International ed. in English), 56, 26, 7644-7647 2017/06/19 Refereed Disclose to all
Nakase I, Noguchi K, Aoki A, Takatani-Nakase T, Fujii I, Futaki S Nakase I, Noguchi K, Aoki A, Takatani-Nakase T, Fujii I, Futaki S Nakase I, Noguchi K, Aoki A, Takatani-Nakase T, Fujii I, Futaki S Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery. Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery. Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery. Scientific reports, 7, 1, 1991 Scientific reports, 7, 1, 1991 Scientific reports, 7, 1, 1991 2017/05/16 Refereed Disclose to all
Futaki S Futaki S Futaki S [Membrane translocation of arginine-rich cell-penetrating peptides]. [Membrane translocation of arginine-rich cell-penetrating peptides]. [Membrane translocation of arginine-rich cell-penetrating peptides]. Seikagaku. The Journal of Japanese Biochemical Society, 89, 1, 8-14 Seikagaku. The Journal of Japanese Biochemical Society, 89, 1, 8-14 Seikagaku. The Journal of Japanese Biochemical Society, 89, 1, 8-14 2017/02 Refereed Disclose to all
I. Nakase, N. Ueno, N. Ueno, M. Katayama, M. Katayama, K. Noguchi, K. Noguchi, T. Takatani-Nakase, N. B. Kobayashi, N. B. Kobayashi, T. Yoshida, T. Yoshida, I. Fujii, S. Futaki I. Nakase, N. Ueno, N. Ueno, M. Katayama, M. Katayama, K. Noguchi, K. Noguchi, T. Takatani-Nakase, N. B. Kobayashi, N. B. Kobayashi, T. Yoshida, T. Yoshida, I. Fujii, S. Futaki I. Nakase, N. Ueno, N. Ueno, M. Katayama, M. Katayama, K. Noguchi, K. Noguchi, T. Takatani-Nakase, N. B. Kobayashi, N. B. Kobayashi, T. Yoshida, T. Yoshida, I. Fujii, S. Futaki Receptor clustering and activation by multivalent interaction through recognition peptides presented on exosomes Receptor clustering and activation by multivalent interaction through recognition peptides presented on exosomes Receptor clustering and activation by multivalent interaction through recognition peptides presented on exosomes Chemical Communications, 53, 317-320 Chemical Communications, 53, 317-320 Chemical Communications, 53, 317-320 2017/01/01 Disclose to all
Miki Imanishi, Shogo Tsuji, Akiyo Suda, Shiroh Futaki Miki Imanishi, Shogo Tsuji, Akiyo Suda, Shiroh Futaki Miki Imanishi, Shogo Tsuji, Akiyo Suda, Shiroh Futaki Detection of: N<sup>6</sup>-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease Detection of: N<sup>6</sup>-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease Detection of: N<sup>6</sup>-methyladenosine based on the methyl-sensitivity of MazF RNA endonuclease Chemical Communications, 53, 12930-12933 Chemical Communications, 53, 12930-12933 Chemical Communications, 53, 12930-12933 2017/01/01 Disclose to all
Shiroh Futaki Shiroh Futaki Shiroh Futaki Membrane translocation of arginine-rich cell-penetrating peptides Membrane translocation of arginine-rich cell-penetrating peptides Membrane translocation of arginine-rich cell-penetrating peptides Seikagaku, 89, 8-14 Seikagaku, 89, 8-14 Seikagaku, 89, 8-14 2017/01/01 Disclose to all
Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S Calmodulin EF-hand peptides as Ca<sup>2+</sup> -switchable recognition tags. Calmodulin EF-hand peptides as Ca<sup>2+</sup> -switchable recognition tags. Calmodulin EF-hand peptides as Ca<sup>2+</sup> -switchable recognition tags. Biopolymers, 108, 1 Biopolymers, 108, 1 Biopolymers, 108, 1 2017/01 Refereed Disclose to all
Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN Backlund CM, Sgolastra F, Otter R, Minter L, Takeuchi T, Futaki S, Tew GN Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization. Polymer chemistry, 7, 48, 7514-7521 Polymer chemistry, 7, 48, 7514-7521 Polymer chemistry, 7, 48, 7514-7521 2016/12/28 Refereed Disclose to all
Tsuji S, Futaki S, Imanishi M Tsuji S, Futaki S, Imanishi M Tsuji S, Futaki S, Imanishi M Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein. Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein. Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein. Chemical communications (Cambridge, England), 52, 99, 14241-14241 Chemical communications (Cambridge, England), 52, 99, 14241-14241 Chemical communications (Cambridge, England), 52, 99, 14241-14241 2016/12 Refereed Disclose to all
Murayama T, Pujals S, Hirose H, Nakase I, Futaki S Murayama T, Pujals S, Hirose H, Nakase I, Futaki S Murayama T, Pujals S, Hirose H, Nakase I, Futaki S Effect of amino acid substitution in the hydrophobic face of amphiphilic peptides on membrane curvature and perturbation: N-terminal helix derived from adenovirus internal protein VI as a model. Effect of amino acid substitution in the hydrophobic face of amphiphilic peptides on membrane curvature and perturbation: N-terminal helix derived from adenovirus internal protein VI as a model. Effect of amino acid substitution in the hydrophobic face of amphiphilic peptides on membrane curvature and perturbation: N-terminal helix derived from adenovirus internal protein VI as a model. Biopolymers, 106, 4, 430-439 Biopolymers, 106, 4, 430-439 Biopolymers, 106, 4, 430-439 2016/11 Refereed Disclose to all
Miyajima R, Tsuda Y, Inokuma T, Shigenaga A, Imanishi M, Futaki S, Otaka A Miyajima R, Tsuda Y, Inokuma T, Shigenaga A, Imanishi M, Futaki S, Otaka A Miyajima R, Tsuda Y, Inokuma T, Shigenaga A, Imanishi M, Futaki S, Otaka A Preparation of peptide thioesters from naturally occurring sequences using reaction sequence consisting of regioselective S-cyanylation and hydrazinolysis. Preparation of peptide thioesters from naturally occurring sequences using reaction sequence consisting of regioselective S-cyanylation and hydrazinolysis. Preparation of peptide thioesters from naturally occurring sequences using reaction sequence consisting of regioselective S-cyanylation and hydrazinolysis. Biopolymers, 106, 4, 531-546 Biopolymers, 106, 4, 531-546 Biopolymers, 106, 4, 531-546 2016/11 Refereed Disclose to all
Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. Biological & pharmaceutical bulletin, 39, 11, 1829-1829 Biological & pharmaceutical bulletin, 39, 11, 1829-1829 Biological & pharmaceutical bulletin, 39, 11, 1829-1829 2016/11 Refereed Disclose to all
Nakase I, Noguchi K, Fujii I, Futaki S Nakase I, Noguchi K, Fujii I, Futaki S Nakase I, Noguchi K, Fujii I, Futaki S Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis. Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis. Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis. Scientific reports, 6 Scientific reports, 6 Scientific reports, 6 2016/10/17 Refereed Disclose to all
Takeuchi T, Futaki S Takeuchi T, Futaki S Takeuchi T, Futaki S Current Understanding of Direct Translocation of Arginine-Rich Cell-Penetrating Peptides and Its Internalization Mechanisms. Current Understanding of Direct Translocation of Arginine-Rich Cell-Penetrating Peptides and Its Internalization Mechanisms. Current Understanding of Direct Translocation of Arginine-Rich Cell-Penetrating Peptides and Its Internalization Mechanisms. Chemical & pharmaceutical bulletin, 64, 10, 1437-1437 Chemical & pharmaceutical bulletin, 64, 10, 1437-1437 Chemical & pharmaceutical bulletin, 64, 10, 1437-1437 2016/10 Refereed Disclose to all
Backlund CM, Takeuchi T, Futaki S, Tew GN Backlund CM, Takeuchi T, Futaki S, Tew GN Backlund CM, Takeuchi T, Futaki S, Tew GN Relating structure and internalization for ROMP-based protein mimics. Relating structure and internalization for ROMP-based protein mimics. Relating structure and internalization for ROMP-based protein mimics. Biochimica et biophysica acta, 1858, 7,Pt.A, 1450-1450 Biochimica et biophysica acta, 1858, 7,Pt.A, 1450-1450 Biochimica et biophysica acta, 1858, 7,Pt.A, 1450-1450 2016/07 Refereed Disclose to all
Kawaguchi Y, Takeuchi T, Kuwata K, Chiba J, Hatanaka Y, Nakase I, Futaki S Kawaguchi Y, Takeuchi T, Kuwata K, Chiba J, Hatanaka Y, Nakase I, Futaki S Kawaguchi Y, Takeuchi T, Kuwata K, Chiba J, Hatanaka Y, Nakase I, Futaki S Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides. Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides. Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides. Bioconjugate chemistry, 27, 4, 1130-1130 Bioconjugate chemistry, 27, 4, 1130-1130 Bioconjugate chemistry, 27, 4, 1130-1130 2016/04 Refereed Disclose to all
Shogo Tsuji, Shiroh Futaki, Miki Imanishi Shogo Tsuji, Shiroh Futaki, Miki Imanishi Shogo Tsuji, Shiroh Futaki, Miki Imanishi Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein Sequence-specific recognition of methylated DNA by an engineered transcription activator-like effector protein Chemical Communications, 52, 14238-14241 Chemical Communications, 52, 14238-14241 Chemical Communications, 52, 14238-14241 2016/01/01 Disclose to all
Yoshihiro Kuroda, Nahoko Kato-Kogoe, Emi Tasaki, Mayumi Yuasa-Sunagawa, Koji Yamanegi, Keiji Nakasyo, Ikuhiko Nakase, Shiroh Futaki, Yumi Tohyama, Munetaka Hirose Yoshihiro Kuroda, Nahoko Kato-Kogoe, Emi Tasaki, Mayumi Yuasa-Sunagawa, Koji Yamanegi, Keiji Nakasyo, Ikuhiko Nakase, Shiroh Futaki, Yumi Tohyama, Munetaka Hirose Yoshihiro Kuroda, Nahoko Kato-Kogoe, Emi Tasaki, Mayumi Yuasa-Sunagawa, Koji Yamanegi, Keiji Nakasyo, Ikuhiko Nakase, Shiroh Futaki, Yumi Tohyama, Munetaka Hirose Erratum: Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells (European Journal of Pharmacology (2015) 765 24-33)) Erratum: Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells (European Journal of Pharmacology (2015) 765 24-33)) Erratum: Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells (European Journal of Pharmacology (2015) 765 24-33)) European Journal of Pharmacology, 767, 220 European Journal of Pharmacology, 767, 220 European Journal of Pharmacology, 767, 220 2015/11/15 Disclose to all
Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells. Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells. Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells. European journal of pharmacology, 765, 24-33 European journal of pharmacology, 765, 24-33 European journal of pharmacology, 765, 24-33 2015/10/15 Refereed Disclose to all
Backlund Coralie, Takeuchi Toshihide, Futaki Shiroh, Tew Gregory Backlund Coralie, Takeuchi Toshihide, Futaki Shiroh, Tew Gregory Backlund Coralie, Takeuchi Toshihide, Futaki Shiroh, Tew Gregory Determining the relationship between structure, internalization, and delivery efficiency for protein mimics Determining the relationship between structure, internalization, and delivery efficiency for protein mimics Determining the relationship between structure, internalization, and delivery efficiency for protein mimics ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 250 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 250 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 250 2015/08/16 Refereed Disclose to all
I. Nakase; S. Futaki Nakase I, Futaki S I. Nakase; S. Futaki Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes. Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes Scientific Reports, 5 Scientific reports, 5 Scientific Reports, 5 2015/05/26 Refereed English Research paper(scientific journal) Disclose to all
T. Takeuchi; M. Suzuki; N. Fujikake; H. A. Popiel; H. Kikuchi; S. Futaki; K. Wada; Y. Nagai Takeuchi T, Suzuki M, Fujikake N, Popiel HA, Kikuchi H, Futaki S, Wada K, Nagai Y T. Takeuchi; M. Suzuki; N. Fujikake; H. A. Popiel; H. Kikuchi; S. Futaki; K. Wada; Y. Nagai Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level. Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level Proceedings of the National Academy of Sciences of the United States of America, 112, 19, E2497-E2506 Proceedings of the National Academy of Sciences of the United States of America, 112, 19, E2497-E2506 Proceedings of the National Academy of Sciences of the United States of America, 112, 19, E2497-E2506 2015/05/12 Refereed English Research paper(scientific journal) Disclose to all
I. Nakase; Y. Kawaguchi; M. Nomizu; S. Futaki NAKASE Ikuhiko, KAWAGUCHI Yoshimasa, NOMIZU Motoyoshi, FUTAKI Shiroh I. Nakase; Y. Kawaguchi; M. Nomizu; S. Futaki Cellular uptake of arginine-rich cell-penetrating peptides and the contribution of membrane-associated proteoglycans アルギニンに富む塩基性ペプチドの細胞内への取り込みと膜結合型プロテオグリカンの寄与 Cellular uptake of arginine-rich cell-penetrating peptides and the contribution of membrane-associated proteoglycans Trends in Glycoscience and Glycotechnology, 27, 155, 81-88 Trends in Glycoscience and Glycotechnology, 27, 155, 81-88 Trends in Glycoscience and Glycotechnology, 27, 155, 81-88 2015/05 Refereed English Research paper(scientific journal) Disclose to all
Nakase I, Takeuchi T, Futaki S Nakase I, Takeuchi T, Futaki S Nakase I, Takeuchi T, Futaki S Cell Penetrating Peptides for Chemical Biological Studies. Cell Penetrating Peptides for Chemical Biological Studies. Cell Penetrating Peptides for Chemical Biological Studies. Methods in molecular biology (Clifton, N.J.), 1324, 387-396 Methods in molecular biology (Clifton, N.J.), 1324, 387-396 Methods in molecular biology (Clifton, N.J.), 1324, 387-396 2015 Refereed Disclose to all
T. Takeuchi; H. A. Popiel; S. Futaki; K. Wada; Y. Nagai Takeuchi T, Popiel HA, Futaki S, Wada K, Nagai Y T. Takeuchi; H. A. Popiel; S. Futaki; K. Wada; Y. Nagai Peptide-based therapeutic approaches for treatment of the polyglutamine diseases Peptide-based therapeutic approaches for treatment of the polyglutamine diseases. Peptide-based therapeutic approaches for treatment of the polyglutamine diseases Current Medicinal Chemistry, 21, 23, 2575-2582 Current medicinal chemistry, 21, 23, 2575-2582 Current Medicinal Chemistry, 21, 23, 2575-2582 2014/08 Refereed English Disclose to all
Y. Azuma; T. Kükenshöner; G. Ma; J.-I. Yasunaga; M. Imanishi; G. Tanaka; I. Nakase; T. Maruno; Y. Kobayashi; K. M. Arndt; M. Matsuoka; S. Futaki Azuma Y, Kükenshöner T, Ma G, Yasunaga J, Imanishi M, Tanaka G, Nakase I, Maruno T, Kobayashi Y, Arndt KM, Matsuoka M, Futaki S Y. Azuma; T. Kükenshöner; G. Ma; J.-I. Yasunaga; M. Imanishi; G. Tanaka; I. Nakase; T. Maruno; Y. Kobayashi; K. M. Arndt; M. Matsuoka; S. Futaki Controlling leucine-zipper partner recognition in cells through modification of a-g interactions Controlling leucine-zipper partner recognition in cells through modification of a-g interactions. Controlling leucine-zipper partner recognition in cells through modification of a-g interactions Chemical Communications, 50, 48, 6364-6367 Chemical communications (Cambridge, England), 50, 48, 6364-6367 Chemical Communications, 50, 48, 6364-6367 2014/06 Refereed English Research paper(scientific journal) Disclose to all
I. Nakase; K. Osaki; G. Tanaka; A. Utani; S. Futaki Nakase I, Osaki K, Tanaka G, Utani A, Futaki S I. Nakase; K. Osaki; G. Tanaka; A. Utani; S. Futaki Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα. Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα Biochemical and Biophysical Research Communications, 446, 4, 857-862 Biochemical and biophysical research communications, 446, 4, 857-862 Biochemical and Biophysical Research Communications, 446, 4, 857-862 2014/04/18 Refereed English Disclose to all
S. Futaki; D. Noshiro; T. Kiwada; K. Asami Futaki S, Noshiro D, Kiwada T, Asami K S. Futaki; D. Noshiro; T. Kiwada; K. Asami Extramembrane control of ion channel peptide assemblies, using alamethicin as an example Extramembrane control of ion channel peptide assemblies, using alamethicin as an example. Extramembrane control of ion channel peptide assemblies, using alamethicin as an example Accounts of Chemical Research, 46, 12, 2924-2933 Accounts of chemical research, 46, 12, 2924-2933 Accounts of Chemical Research, 46, 12, 2924-2933 2013/12/17 Refereed English Disclose to all
Kenji Mishiro, Takumi Furuta, Takahiro Sasamori, Kazuhiro Hayashi, Norihiro Tokitoh, Shiroh Futaki, Takeo Kawabata Kenji Mishiro, Takumi Furuta, Takahiro Sasamori, Kazuhiro Hayashi, Norihiro Tokitoh, Shiroh Futaki, Takeo Kawabata Kenji Mishiro, Takumi Furuta, Takahiro Sasamori, Kazuhiro Hayashi, Norihiro Tokitoh, Shiroh Futaki, Takeo Kawabata Erratum: A cyclochiral conformational motif constructed using a robust hydrogen-bonding network (Journal of the American Chemical Society (2013) 135 (13644-13647) DOI: 10.1021/ja407051k) Erratum: A cyclochiral conformational motif constructed using a robust hydrogen-bonding network (Journal of the American Chemical Society (2013) 135 (13644-13647) DOI: 10.1021/ja407051k) Erratum: A cyclochiral conformational motif constructed using a robust hydrogen-bonding network (Journal of the American Chemical Society (2013) 135 (13644-13647) DOI: 10.1021/ja407051k) Journal of the American Chemical Society, 135, 17236 Journal of the American Chemical Society, 135, 17236 Journal of the American Chemical Society, 135, 17236 2013/11/13 Disclose to all
S. Tsuji; S. Futaki; M. Imanishi Tsuji S, Futaki S, Imanishi M S. Tsuji; S. Futaki; M. Imanishi Creating a TALE protein with unbiased 5′-T binding Creating a TALE protein with unbiased 5'-T binding. Creating a TALE protein with unbiased 5′-T binding Biochemical and Biophysical Research Communications, 441, 1, 262-265 Biochemical and biophysical research communications, 441, 1, 262-265 Biochemical and Biophysical Research Communications, 441, 1, 262-265 2013/11/08 Refereed English Disclose to all
Y. Shimatani; M. Ito; T. Ohgita; A. Yamada; S. Hama; A. Gräslund; S. Lindberg; Ü. Langel; H. Harashima; I. Nakase; S. Futaki; K. Kogure Mitsueda A, Shimatani Y, Ito M, Ohgita T, Yamada A, Hama S, Gräslund A, Lindberg S, Langel Ü, Harashima H, Nakase I, Futaki S, Kogure K Y. Shimatani; M. Ito; T. Ohgita; A. Yamada; S. Hama; A. Gräslund; S. Lindberg; Ü. Langel; H. Harashima; I. Nakase; S. Futaki; K. Kogure Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex Asako Mitsueda,1 Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex. Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex Asako Mitsueda,1 Biopolymers, 100, 6, 698-704 Biopolymers, 100, 6, 698-704 Biopolymers, 100, 6, 698-704 2013/11 Refereed English Disclose to all
K. Mishiro; T. Furuta; T. Sasamori; K. Hayashi; N. Tokitoh; S. Futaki; T. Kawabata Mishiro K, Furuta T, Sasamori T, Hayashi K, Tokitoh N, Futaki S, Kawabata T K. Mishiro; T. Furuta; T. Sasamori; K. Hayashi; N. Tokitoh; S. Futaki; T. Kawabata A cyclochiral conformational motif constructed using a robust hydrogen-bonding network A cyclochiral conformational motif constructed using a robust hydrogen-bonding network. A cyclochiral conformational motif constructed using a robust hydrogen-bonding network Journal of the American Chemical Society, 135, 37, 13644-13647 Journal of the American Chemical Society, 135, 37, 13644-13647 Journal of the American Chemical Society, 135, 37, 13644-13647 2013/09/18 Refereed English Disclose to all
S. Pujals; H. Miyamae; S. Afonin; T. Murayama; H. Hirose; I. Nakase; K. Taniuchi; M. Umeda; K. Sakamoto; A.S. Ulrich; S. Futaki Pujals S, Miyamae H, Afonin S, Murayama T, Hirose H, Nakase I, Taniuchi K, Umeda M, Sakamoto K, Ulrich AS, Futaki S S. Pujals; H. Miyamae; S. Afonin; T. Murayama; H. Hirose; I. Nakase; K. Taniuchi; M. Umeda; K. Sakamoto; A.S. Ulrich; S. Futaki Curvature engineering: Positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginine Curvature engineering: positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginine. Curvature engineering: Positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginine ACS Chemical Biology, 8, 9, 1894-1899 ACS chemical biology, 8, 9, 1894-1899 ACS Chemical Biology, 8, 9, 1894-1899 2013/09 Refereed English Disclose to all
S. Katayama; I. Nakase; Y. Yano; T. Murayama; Y. Nakata; K. Matsuzaki; S. Futaki Katayama S, Nakase I, Yano Y, Murayama T, Nakata Y, Matsuzaki K, Futaki S S. Katayama; I. Nakase; Y. Yano; T. Murayama; Y. Nakata; K. Matsuzaki; S. Futaki Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: Recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature. Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: Recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature Biochimica et Biophysica Acta - Biomembranes, 1828, 9, 2134-2142 Biochimica et biophysica acta, 1828, 9, 2134-2142 Biochimica et Biophysica Acta - Biomembranes, 1828, 9, 2134-2142 2013/09 Refereed English Disclose to all
Y. Kawaguchi; G. Tanaka; I. Nakase; M. Imanishi; J. Chiba; Y. Hatanaka; S. Futaki Kawaguchi Y, Tanaka G, Nakase I, Imanishi M, Chiba J, Hatanaka Y, Futaki S Y. Kawaguchi; G. Tanaka; I. Nakase; M. Imanishi; J. Chiba; Y. Hatanaka; S. Futaki Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking. Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking Bioorganic and Medicinal Chemistry Letters, 23, 13, 3738-3740 Bioorganic & medicinal chemistry letters, 23, 13, 3738-3740 Bioorganic and Medicinal Chemistry Letters, 23, 13, 3738-3740 2013/07/01 Refereed English Disclose to all
C. Gehin; J. Montenegro; E.-K. Bang; A. Cajaraville; S. Takayama; H. Hirose; S. Futaki; S. Matile; H. Riezman Gehin C, Montenegro J, Bang EK, Cajaraville A, Takayama S, Hirose H, Futaki S, Matile S, Riezman H C. Gehin; J. Montenegro; E.-K. Bang; A. Cajaraville; S. Takayama; H. Hirose; S. Futaki; S. Matile; H. Riezman Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts. Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts Journal of the American Chemical Society, 135, 25, 9295-9298 Journal of the American Chemical Society, 135, 25, 9295-9298 Journal of the American Chemical Society, 135, 25, 9295-9298 2013/06/26 Refereed English Disclose to all
C.M. Yamazaki; I. Nakase; H. Endo; S. Kishimoto; Y. Mashiyama; R. Masuda; S. Futaki; T. Koide Yamazaki CM, Nakase I, Endo H, Kishimoto S, Mashiyama Y, Masuda R, Futaki S, Koide T C.M. Yamazaki; I. Nakase; H. Endo; S. Kishimoto; Y. Mashiyama; R. Masuda; S. Futaki; T. Koide Collagen-like cell-penetrating peptides Collagen-like cell-penetrating peptides. Collagen-like cell-penetrating peptides Angewandte Chemie - International Edition, 52, 21, 5497-5500 Angewandte Chemie (International ed. in English), 52, 21, 5497-5500 Angewandte Chemie - International Edition, 52, 21, 5497-5500 2013/05 Refereed English Disclose to all
I. Nakase; G. Tanaka; S. Futaki Nakase I, Tanaka G, Futaki S I. Nakase; G. Tanaka; S. Futaki Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells. Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells Molecular BioSystems, 9, 5, 855-861 Molecular bioSystems, 9, 5, 855-861 Molecular BioSystems, 9, 5, 855-861 2013/05 Refereed English Disclose to all
S. Futaki; H. Hirose; I. Nakase Futaki S, Hirose H, Nakase I S. Futaki; H. Hirose; I. Nakase Arginine-rich peptides: Methods of translocation through biological membranes Arginine-rich peptides: methods of translocation through biological membranes. Arginine-rich peptides: Methods of translocation through biological membranes Current Pharmaceutical Design, 19, 16, 2863-2868 Current pharmaceutical design, 19, 16, 2863-2868 Current Pharmaceutical Design, 19, 16, 2863-2868 2013/05 Refereed English Disclose to all
F. Madani; R. Abdo; S. Lindberg; H. Hirose; S. Futaki; Ü. Langel; A. Gräslund Madani F, Abdo R, Lindberg S, Hirose H, Futaki S, Langel U, Gräslund A F. Madani; R. Abdo; S. Lindberg; H. Hirose; S. Futaki; Ü. Langel; A. Gräslund Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient. Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient Biochimica et Biophysica Acta - Biomembranes, 1828, 4, 1198-1204 Biochimica et biophysica acta, 1828, 4, 1198-1204 Biochimica et Biophysica Acta - Biomembranes, 1828, 4, 1198-1204 2013/04 Refereed English Disclose to all
D. Noshiro; K. Sonomura; H.-H. Yu; M. Imanishi; K. Asami; S. Futaki Noshiro D, Sonomura K, Yu HH, Imanishi M, Asami K, Futaki S D. Noshiro; K. Sonomura; H.-H. Yu; M. Imanishi; K. Asami; S. Futaki Construction of a Ca<sup>2+</sup>-gated artificial channel by fusing alamethicin with a calmodulin-derived extramembrane segment Construction of a Ca(2+)-gated artificial channel by fusing alamethicin with a calmodulin-derived extramembrane segment. Construction of a Ca<sup>2+</sup>-gated artificial channel by fusing alamethicin with a calmodulin-derived extramembrane segment Bioconjugate Chemistry, 24, 2, 188-195 Bioconjugate chemistry, 24, 2, 188-195 Bioconjugate Chemistry, 24, 2, 188-195 2013/02 Refereed English Disclose to all
Y. Kuroda; N. Kato-Kogoe; E. Tasaki; E. Murata; K. Ueda; M. Abe; K. Miyamoto; I. Nakase; S. Futaki; Y. Tohyama; M. Hirose Kuroda Y, Kato-Kogoe N, Tasaki E, Murata E, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M Y. Kuroda; N. Kato-Kogoe; E. Tasaki; E. Murata; K. Ueda; M. Abe; K. Miyamoto; I. Nakase; S. Futaki; Y. Tohyama; M. Hirose Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells. Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells European Journal of Pharmacology, 698, 1-3, 87-94 European journal of pharmacology, 698, 1-3, 87-94 European Journal of Pharmacology, 698, 1-3, 87-94 2013/01/05 Refereed English Research paper(scientific journal) Disclose to all
D. Noshiro; K. Asami; S. Futaki Noshiro D, Asami K, Futaki S D. Noshiro; K. Asami; S. Futaki Control of leakage activities of alamethicin analogs by metals: Side chain-dependent adverse gating response to Zn<sup>2+</sup> Control of leakage activities of alamethicin analogs by metals: side chain-dependent adverse gating response to Zn(2+). Control of leakage activities of alamethicin analogs by metals: Side chain-dependent adverse gating response to Zn<sup>2+</sup> Bioorganic and Medicinal Chemistry, 20, 23, 6870-6876 Bioorganic & medicinal chemistry, 20, 23, 6870-6876 Bioorganic and Medicinal Chemistry, 20, 23, 6870-6876 2012/12/01 Refereed English Disclose to all
Y. Ueda; F.-Y. Wei; T.-I. Hide; H. Michiue; K. Takayama; T. Kaitsuka; H. Nakamura; K. Makino; J.-I. Kuratsu; S. Futaki; K. Tomizawa Ueda Y, Wei FY, Hide T, Michiue H, Takayama K, Kaitsuka T, Nakamura H, Makino K, Kuratsu J, Futaki S, Tomizawa K Y. Ueda; F.-Y. Wei; T.-I. Hide; H. Michiue; K. Takayama; T. Kaitsuka; H. Nakamura; K. Makino; J.-I. Kuratsu; S. Futaki; K. Tomizawa Induction of autophagic cell death of glioma-initiating cells by cell-penetrating d-isomer peptides consisting of Pas and the p53 C-terminus Induction of autophagic cell death of glioma-initiating cells by cell-penetrating D-isomer peptides consisting of Pas and the p53 C-terminus. Induction of autophagic cell death of glioma-initiating cells by cell-penetrating d-isomer peptides consisting of Pas and the p53 C-terminus Biomaterials, 33, 35, 9061-9069 Biomaterials, 33, 35, 9061-9069 Biomaterials, 33, 35, 9061-9069 2012/12 Refereed English Disclose to all
G. Tanaka; I. Nakase; Y. Fukuda; R. Masuda; S. Oishi; K. Shimura; Y. Kawaguchi; T. Takatani-Nakase; Ü. Langel; A. Gräslund; K. Okawa; M. Matsuoka; N. Fujii; Y. Hatanaka; S. Futaki Tanaka G, Nakase I, Fukuda Y, Masuda R, Oishi S, Shimura K, Kawaguchi Y, Takatani-Nakase T, Langel U, Gräslund A, Okawa K, Matsuoka M, Fujii N, Hatanaka Y, Futaki S G. Tanaka; I. Nakase; Y. Fukuda; R. Masuda; S. Oishi; K. Shimura; Y. Kawaguchi; T. Takatani-Nakase; Ü. Langel; A. Gräslund; K. Okawa; M. Matsuoka; N. Fujii; Y. Hatanaka; S. Futaki CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV. CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV Chemistry and Biology, 19, 11, 1437-1446 Chemistry & biology, 19, 11, 1437-1446 Chemistry and Biology, 19, 11, 1437-1446 2012/11/21 Refereed English Disclose to all
I. Nakase; S. Okumura; S. Katayama; H. Hirose; S. Pujals; H. Yamaguchi; S. Arakawa; S. Shimizu; S. Futaki Nakase I, Okumura S, Katayama S, Hirose H, Pujals S, Yamaguchi H, Arakawa S, Shimizu S, Futaki S I. Nakase; S. Okumura; S. Katayama; H. Hirose; S. Pujals; H. Yamaguchi; S. Arakawa; S. Shimizu; S. Futaki Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine. Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine Chemical Communications, 48, 90, 11097-11099 Chemical communications (Cambridge, England), 48, 90, 11097-11099 Chemical Communications, 48, 90, 11097-11099 2012/11 Refereed English Disclose to all
M. Imanishi; K. Yamamoto; H. Yamada; Y. Hirose; H. Okamura; S. Futaki Imanishi M, Yamamoto K, Yamada H, Hirose Y, Okamura H, Futaki S M. Imanishi; K. Yamamoto; H. Yamada; Y. Hirose; H. Okamura; S. Futaki Construction of a rhythm transfer system that mimics the cellular clock Construction of a rhythm transfer system that mimics the cellular clock. Construction of a rhythm transfer system that mimics the cellular clock ACS Chemical Biology, 7, 11, 1817-1821 ACS chemical biology, 7, 11, 1817-1821 ACS Chemical Biology, 7, 11, 1817-1821 2012/11 Refereed English Disclose to all
K. Sakamoto; K. Aburai; T. Morishita; K. Sakai; H. Sakai; M. Abe; I. Nakase; S. Futaki Sakamoto Kazutami, Aburai Kenichi, Morishita Taku, Sakai Kenichi, Sakai Hideki, Abe Masahiko, Nakase Ikuhiko, Futaki Shiroh K. Sakamoto; K. Aburai; T. Morishita; K. Sakai; H. Sakai; M. Abe; I. Nakase; S. Futaki Bioinspired mechanism for the translocation of peptide through the cell membrane Bioinspired Mechanism for the Translocation of Peptide through the Cell Membrane Bioinspired mechanism for the translocation of peptide through the cell membrane Chemistry Letters, 41, 10, 1078-1080 CHEMISTRY LETTERS, 41, 10, 1078-1080 Chemistry Letters, 41, 10, 1078-1080 2012/10/05 Refereed Disclose to all
Y. Azuma; H. Imai; T. Yoshimura; T. Kawabata; M. Imanishi; S. Futaki Azuma Y, Imai H, Yoshimura T, Kawabata T, Imanishi M, Futaki S Y. Azuma; H. Imai; T. Yoshimura; T. Kawabata; M. Imanishi; S. Futaki Dipicolylamine as a unique structural switching element for helical peptides Dipicolylamine as a unique structural switching element for helical peptides. Dipicolylamine as a unique structural switching element for helical peptides Organic and Biomolecular Chemistry, 10, 30, 6062-6068 Organic & biomolecular chemistry, 10, 30, 6062-6068 Organic and Biomolecular Chemistry, 10, 30, 6062-6068 2012/08 Refereed English Disclose to all
I. Nakase; H. Akita; K. Kogure; A. Gräslund; U. Langel; H. Harashima; S. Futaki Nakase I, Akita H, Kogure K, Gräslund A, Langel U, Harashima H, Futaki S I. Nakase; H. Akita; K. Kogure; A. Gräslund; U. Langel; H. Harashima; S. Futaki Efficient intracellular delivery of nucleic acid pharmaceuticals using cell-penetrating peptides Efficient intracellular delivery of nucleic acid pharmaceuticals using cell-penetrating peptides. Efficient intracellular delivery of nucleic acid pharmaceuticals using cell-penetrating peptides Accounts of Chemical Research, 45, 7, 1132-1139 Accounts of chemical research, 45, 7, 1132-1139 Accounts of Chemical Research, 45, 7, 1132-1139 2012/07/17 Refereed English Disclose to all
I. Nakase; S. Okumura; G. Tanaka; K. Osaki; M. Imanishi; S. Futaki Nakase I, Okumura S, Tanaka G, Osaki K, Imanishi M, Futaki S I. Nakase; S. Okumura; G. Tanaka; K. Osaki; M. Imanishi; S. Futaki Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand. Signal transduction using an artificial receptor system that undergoes dimerization upon addition of a bivalent leucine-zipper ligand Angewandte Chemie - International Edition, 51, 30, 7464-7467 Angewandte Chemie (International ed. in English), 51, 30, 7464-7467 Angewandte Chemie - International Edition, 51, 30, 7464-7467 2012/07 Refereed English Disclose to all
K. Takayama; H. Hirose; G. Tanaka; S. Pujals; S. Katayama; I. Nakase; S. Futaki Takayama K, Hirose H, Tanaka G, Pujals S, Katayama S, Nakase I, Futaki S K. Takayama; H. Hirose; G. Tanaka; S. Pujals; S. Katayama; I. Nakase; S. Futaki Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery. Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery Molecular Pharmaceutics, 9, 5, 1222-1230 Molecular pharmaceutics, 9, 5, 1222-1230 Molecular Pharmaceutics, 9, 5, 1222-1230 2012/05 Refereed English Disclose to all
H. Hirose; T. Takeuchi; H. Osakada; S. Pujals; S. Katayama; I. Nakase; S. Kobayashi; T. Haraguchi; S. Futaki Hirose H, Takeuchi T, Osakada H, Pujals S, Katayama S, Nakase I, Kobayashi S, Haraguchi T, Futaki S H. Hirose; T. Takeuchi; H. Osakada; S. Pujals; S. Katayama; I. Nakase; S. Kobayashi; T. Haraguchi; S. Futaki Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells. Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells Molecular Therapy, 20, 5, 984-993 Molecular therapy : the journal of the American Society of Gene Therapy, 20, 5, 984-993 Molecular Therapy, 20, 5, 984-993 2012/05 Refereed English Disclose to all
I. Nakase; Y. Konishi; M. Ueda; H. Saji; S. Futaki Nakase I, Konishi Y, Ueda M, Saji H, Futaki S I. Nakase; Y. Konishi; M. Ueda; H. Saji; S. Futaki Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo. Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo Journal of Controlled Release, 159, 2, 181-188 Journal of controlled release : official journal of the Controlled Release Society, 159, 2, 181-188 Journal of Controlled Release, 159, 2, 181-188 2012/04/30 Refereed English Disclose to all
M. Imanishi; K. Matsumura; S. Tsuji; T. Nakaya; S. Negi; S. Futaki; Y. Sugiura Imanishi M, Matsumura K, Tsuji S, Nakaya T, Negi S, Futaki S, Sugiura Y M. Imanishi; K. Matsumura; S. Tsuji; T. Nakaya; S. Negi; S. Futaki; Y. Sugiura Zn(II) binding and DNA binding properties of ligand-substituted CXHH-type zinc finger proteins Zn(II) binding and DNA binding properties of ligand-substituted CXHH-type zinc finger proteins. Zn(II) binding and DNA binding properties of ligand-substituted CXHH-type zinc finger proteins Biochemistry, 51, 16, 3342-3348 Biochemistry, 51, 16, 3342-3348 Biochemistry, 51, 16, 3342-3348 2012/04/24 Refereed English Disclose to all
H. Kono; M. Imanishi; S. Negi; K. Tatsutani; Y. Sakaeda; A. Hashimoto; C. Nakayama; S. Futaki; Y. Sugiura Kono H, Imanishi M, Negi S, Tatsutani K, Sakaeda Y, Hashimoto A, Nakayama C, Futaki S, Sugiura Y H. Kono; M. Imanishi; S. Negi; K. Tatsutani; Y. Sakaeda; A. Hashimoto; C. Nakayama; S. Futaki; Y. Sugiura Rational design of DNA sequence-specific zinc fingers Rational design of DNA sequence-specific zinc fingers. Rational design of DNA sequence-specific zinc fingers FEBS Letters, 586, 6, 918-923 FEBS letters, 586, 6, 918-923 FEBS Letters, 586, 6, 918-923 2012/03/23 Refereed English Disclose to all
T. Ochiai; M. Nagata; K. Shimoyama; T. Kato; T. Asaoka; M. Kondo; T. Dewa; K. Yamashita; A. Kashiwada; S. Futaki; H. Hashimoto; M. Nango Ochiai Tsuyoshi, Nagata Morio, Shimoyama Kosuke, Kato Tomoya, Asaoka Takahide, Kondo Masaharu, Dewa Takehisa, Yamashita Keiji, Kashiwada Ayumi, Futaki Shiroh, Hashimoto Hideki, Nango Mamoru T. Ochiai; M. Nagata; K. Shimoyama; T. Kato; T. Asaoka; M. Kondo; T. Dewa; K. Yamashita; A. Kashiwada; S. Futaki; H. Hashimoto; M. Nango Two-dimensional molecular assembly of bacteriochlorophyll a derivatives using synthetic poly(ethylene glycol)-linked light-harvesting model polypeptides on a gold electrode modified with supported lipid bilayers Two-Dimensional Molecular Assembly of Bacteriochlorophyll a Derivatives Using Synthetic Poly(ethylene glycol)-Linked Light-Harvesting Model Polypeptides on a Gold Electrode Modified with Supported Lipid Bilayers Two-dimensional molecular assembly of bacteriochlorophyll a derivatives using synthetic poly(ethylene glycol)-linked light-harvesting model polypeptides on a gold electrode modified with supported lipid bilayers ACS Macro Letters, 1, 1, 28-32 ACS MACRO LETTERS, 1, 1, 28-32 ACS Macro Letters, 1, 1, 28-32 2012/01 Refereed Disclose to all
S. Kawamoto; T. Miyakawa; M. Takasu; R. Morikawa; T. Oda; H. Saito; S. Futaki; H. Nagao Kawamoto Shuhei, Miyakawa Takeshi, Takasu Masako, Morikawa Ryota, Oda Tatsuki, Saito Hiroaki, Futaki Shiroh, Nagao Hidemi S. Kawamoto; T. Miyakawa; M. Takasu; R. Morikawa; T. Oda; H. Saito; S. Futaki; H. Nagao Cell-penetrating peptide induces various deformations of lipid bilayer membrane: Inverted micelle, double bilayer, and transmembrane Cell-Penetrating Peptide Induces Various Deformations of Lipid Bilayer Membrane: Inverted Micelle, Double Bilayer, and Transmembrane Cell-penetrating peptide induces various deformations of lipid bilayer membrane: Inverted micelle, double bilayer, and transmembrane International Journal of Quantum Chemistry, 112, 1, 178-183 INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 112, 1, 178-183 International Journal of Quantum Chemistry, 112, 1, 178-183 2012/01 Refereed Disclose to all
S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao Kawamoto Shuhei, Takasu Masako, Miyakawa Takeshi, Morikawa Ryota, Oda Tatsuki, Futaki Shiroh, Nagao Hidemi S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao Binding of Tat peptides on DOPC and DOPG lipid bilayer membrane studied by molecular dynamics simulations Binding of Tat peptides on DOPC and DOPG lipid bilayer membrane studied by molecular dynamics simulations Binding of Tat peptides on DOPC and DOPG lipid bilayer membrane studied by molecular dynamics simulations Molecular Simulation, 38, 5, 366-368 MOLECULAR SIMULATION, 38, 5, 366-368 Molecular Simulation, 38, 5, 366-368 2012 Refereed Disclose to all
M. Imanishi; A. Nakamura; M. Doi; S. Futaki; H. Okamura Imanishi M, Nakamura A, Doi M, Futaki S, Okamura H M. Imanishi; A. Nakamura; M. Doi; S. Futaki; H. Okamura Control of circadian phase by an artificial zinc finger transcription regulator Control of circadian phase by an artificial zinc finger transcription regulator. Control of circadian phase by an artificial zinc finger transcription regulator Angewandte Chemie - International Edition, 50, 40, 9396-9399 Angewandte Chemie (International ed. in English), 50, 40, 9396-9399 Angewandte Chemie - International Edition, 50, 40, 9396-9399 2011/09 Refereed English Disclose to all
S.M. Shaheen; H. Akita; T. Nakamura; S. Takayama; S. Futaki; A. Yamashita; R. Katoono; N. Yui; H. Harashima Shaheen SM, Akita H, Nakamura T, Takayama S, Futaki S, Yamashita A, Katoono R, Yui N, Harashima H S.M. Shaheen; H. Akita; T. Nakamura; S. Takayama; S. Futaki; A. Yamashita; R. Katoono; N. Yui; H. Harashima KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine. KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine Biomaterials, 32, 26, 6342-6350 Biomaterials, 32, 26, 6342-6350 Biomaterials, 32, 26, 6342-6350 2011/09 Refereed English Disclose to all
C.Y. Looi; M. Imanishi; S. Takaki; M. Sato; N. Chiba; Y. Sasahara; S. Futaki; S. Tsuchiya; S. Kumaki Looi CY, Imanishi M, Takaki S, Sato M, Chiba N, Sasahara Y, Futaki S, Tsuchiya S, Kumaki S C.Y. Looi; M. Imanishi; S. Takaki; M. Sato; N. Chiba; Y. Sasahara; S. Futaki; S. Tsuchiya; S. Kumaki Octa-Arginine mediated delivery of wild-type Lnk protein inhibits TPO-induced M-MOK Megakaryoblastic leukemic cell growth by promoting apoptosis Octa-arginine mediated delivery of wild-type Lnk protein inhibits TPO-induced M-MOK megakaryoblastic leukemic cell growth by promoting apoptosis. Octa-Arginine mediated delivery of wild-type Lnk protein inhibits TPO-induced M-MOK Megakaryoblastic leukemic cell growth by promoting apoptosis PLoS ONE, 6, 8, e23640 PloS one, 6, 8, e23640 PLoS ONE, 6, 8, e23640 2011/08/10 Refereed English Disclose to all
Y. Sakurai; H. Hatakeyama; Y. Sato; H. Akita; K. Takayama; S. Kobayashi; S. Futaki; H. Harashima Sakurai Y, Hatakeyama H, Sato Y, Akita H, Takayama K, Kobayashi S, Futaki S, Harashima H Y. Sakurai; H. Hatakeyama; Y. Sato; H. Akita; K. Takayama; S. Kobayashi; S. Futaki; H. Harashima Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA. Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA Biomaterials, 32, 24, 5733-5742 Biomaterials, 32, 24, 5733-5742 Biomaterials, 32, 24, 5733-5742 2011/08 Refereed English Disclose to all
S. Negi; M. Imanishi; M. Sasaki; K. Tatsutani; S. Futaki; Y. Sugiura Negi S, Imanishi M, Sasaki M, Tatsutani K, Futaki S, Sugiura Y S. Negi; M. Imanishi; M. Sasaki; K. Tatsutani; S. Futaki; Y. Sugiura An arginine residue instead of a conserved leucine residue in the recognition helix of the finger 3 of Zif268 stabilizes the domain structure and mediates DNA binding An arginine residue instead of a conserved leucine residue in the recognition helix of the finger 3 of Zif268 stabilizes the domain structure and mediates DNA binding. An arginine residue instead of a conserved leucine residue in the recognition helix of the finger 3 of Zif268 stabilizes the domain structure and mediates DNA binding Biochemistry, 50, 28, 6266-6272 Biochemistry, 50, 28, 6266-6272 Biochemistry, 50, 28, 6266-6272 2011/07/19 Refereed English Disclose to all
二木史朗 二木史朗 膜透過ペプチドの生体膜透過機構と高分子の細胞内導入 膜透過ペプチドの生体膜透過機構と高分子の細胞内導入 膜, 36, 4, 139-144 膜, 36, 4, 139-144 , 36, 4, 139-144 2011/07/01 Japanese Disclose to all
K. Sonomura; H. Kuyama; E.-I. Matsuo; S. Tsunasawa; S. Futaki; O. Nishimura Sonomura K, Kuyama H, Matsuo E, Tsunasawa S, Futaki S, Nishimura O K. Sonomura; H. Kuyama; E.-I. Matsuo; S. Tsunasawa; S. Futaki; O. Nishimura Selective isolation of N-blocked peptide by combining AspN digestion, transamination, and tosylhydrazine glass treatment Selective isolation of N-blocked peptide by combining AspN digestion, transamination, and tosylhydrazine glass treatment. Selective isolation of N-blocked peptide by combining AspN digestion, transamination, and tosylhydrazine glass treatment Analytical Biochemistry, 410, 2, 214-223 Analytical biochemistry, 410, 2, 214-223 Analytical Biochemistry, 410, 2, 214-223 2011/03/15 Refereed English Disclose to all
S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao Kawamoto S, Takasu M, Miyakawa T, Morikawa R, Oda T, Futaki S, Nagao H S. Kawamoto; M. Takasu; T. Miyakawa; R. Morikawa; T. Oda; S. Futaki; H. Nagao Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: Importance of attractive force between cell-penetrating peptides and lipid head group Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: importance of attractive force between cell-penetrating peptides and lipid head group. Inverted micelle formation of cell-penetrating peptide studied by coarse-grained simulation: Importance of attractive force between cell-penetrating peptides and lipid head group Journal of Chemical Physics, 134, 9, 95103 The Journal of chemical physics, 134, 9, 95103 Journal of Chemical Physics, 134, 9, 95103 2011/03/07 Refereed English Disclose to all
H. Akita; K. Kogure; R. Moriguchi; Y. Nakamura; T. Higashi; T. Nakamura; S. Serada; M. Fujimoto; T. Naka; S. Futaki; H. Harashima Akita H, Kogure K, Moriguchi R, Nakamura Y, Higashi T, Nakamura T, Serada S, Fujimoto M, Naka T, Futaki S, Harashima H H. Akita; K. Kogure; R. Moriguchi; Y. Nakamura; T. Higashi; T. Nakamura; S. Serada; M. Fujimoto; T. Naka; S. Futaki; H. Harashima Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation. Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation Journal of Controlled Release, 149, 1, 58-64 Journal of controlled release : official journal of the Controlled Release Society, 149, 1, 58-64 Journal of Controlled Release, 149, 1, 58-64 2011/01/05 Refereed English Disclose to all
S. Katayama; H. Hirose; K. Takayama; I. Nakase; S. Futaki Katayama S, Hirose H, Takayama K, Nakase I, Futaki S S. Katayama; H. Hirose; K. Takayama; I. Nakase; S. Futaki Acylation of octaarginine: Implication to the use of intracellular delivery vectors Acylation of octaarginine: Implication to the use of intracellular delivery vectors. Acylation of octaarginine: Implication to the use of intracellular delivery vectors Journal of Controlled Release, 149, 1, 29-35 Journal of controlled release : official journal of the Controlled Release Society, 149, 1, 29-35 Journal of Controlled Release, 149, 1, 29-35 2011/01/05 Refereed English Disclose to all
Hiraga Takashi, Ueno Ichiro, Shiga Noriyasu, Watanabe Hirofumi, Futaki Shiroh, Kubo Masaki, Takarada Shigeru, Tanaka Norio Hiraga Takashi, Ueno Ichiro, Shiga Noriyasu, Watanabe Hirofumi, Futaki Shiroh, Kubo Masaki, Takarada Shigeru, Tanaka Norio Hiraga Takashi, Ueno Ichiro, Shiga Noriyasu, Watanabe Hirofumi, Futaki Shiroh, Kubo Masaki, Takarada Shigeru, Tanaka Norio Switching mechanism of an optically-gated optical switch using an organic dye. Switching mechanism of an optically-gated optical switch using an organic dye. Switching mechanism of an optically-gated optical switch using an organic dye. ORGANIC PHOTONIC MATERIALS AND DEVICES XIII, 7935 ORGANIC PHOTONIC MATERIALS AND DEVICES XIII, 7935 ORGANIC PHOTONIC MATERIALS AND DEVICES XIII, 7935 2011 Refereed Disclose to all
A. Gräslund; F. Madani; S. Lindberg; U. Langel; S. Futaki Madani F, Lindberg S, Langel U, Futaki S, Gräslund A A. Gräslund; F. Madani; S. Lindberg; U. Langel; S. Futaki Mechanisms of cellular uptake of cell-penetrating peptides Mechanisms of cellular uptake of cell-penetrating peptides. Mechanisms of cellular uptake of cell-penetrating peptides Journal of Biophysics, 2011, 414729 Journal of biophysics (Hindawi Publishing Corporation : Online), 2011, 414729 Journal of Biophysics, 2011, 414729 2011 Refereed English Disclose to all
I. Nakase; K. Kogure; H. Harashima; S. Futaki Nakase I, Kogure K, Harashima H, Futaki S I. Nakase; K. Kogure; H. Harashima; S. Futaki Application of a fusiogenic peptide GALA for intracellular delivery. Application of a fusiogenic peptide GALA for intracellular delivery. Application of a fusiogenic peptide GALA for intracellular delivery. Methods in molecular biology (Clifton, N.J.), 683, 525-533 Methods in molecular biology (Clifton, N.J.), 683, 525-533 Methods in molecular biology (Clifton, N.J.), 683, 525-533 2011 Refereed English Disclose to all
Futaki Shiroh Futaki Shiroh Futaki Shiroh CHEMICAL AND BIOLOGICAL FACTORS THAT CONTRIBUTE TO THE INTERNALIZATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES CHEMICAL AND BIOLOGICAL FACTORS THAT CONTRIBUTE TO THE INTERNALIZATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES CHEMICAL AND BIOLOGICAL FACTORS THAT CONTRIBUTE TO THE INTERNALIZATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES JOURNAL OF GENE MEDICINE, 12, 12, 1015 JOURNAL OF GENE MEDICINE, 12, 12, 1015 JOURNAL OF GENE MEDICINE, 12, 12, 1015 2010/12 Refereed Disclose to all
Nakase Ikuhiko, Kobayashi Sachiko, Futaki Shiroh Nakase Ikuhiko, Kobayashi Sachiko, Futaki Shiroh Nakase Ikuhiko, Kobayashi Sachiko, Futaki Shiroh Cytosolic delivery of macromolecules using pH-dependent fusogenic peptide Cytosolic delivery of macromolecules using pH-dependent fusogenic peptide Cytosolic delivery of macromolecules using pH-dependent fusogenic peptide DRUG DISCOVERY TODAY, 15, 23-24, 1095 DRUG DISCOVERY TODAY, 15, 23-24, 1095 DRUG DISCOVERY TODAY, 15, 23-24, 1095 2010/12 Refereed Disclose to all
H.-H. Yu; I. Nakase; S. Pujals; H. Hirose; G. Tanaka; S. Katayama; M. Imanishi; S. Futaki Yu HH, Nakase I, Pujals S, Hirose H, Tanaka G, Katayama S, Imanishi M, Futaki S H.-H. Yu; I. Nakase; S. Pujals; H. Hirose; G. Tanaka; S. Katayama; M. Imanishi; S. Futaki Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery. Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery Biochimica et Biophysica Acta - Biomembranes, 1798, 12, 2249-2257 Biochimica et biophysica acta, 1798, 12, 2249-2257 Biochimica et Biophysica Acta - Biomembranes, 1798, 12, 2249-2257 2010/12 Refereed English Disclose to all
R. Miyamoto; H. Akizawa; T. Nishikawa; T. Uehara; Y. Azuma; I. Nakase; S. Futaki; H. Hanaoka; Y. Iida; K. Endo; Y. Arano Miyamoto R, Akizawa H, Nishikawa T, Uehara T, Azuma Y, Nakase I, Futaki S, Hanaoka H, Iida Y, Endo K, Arano Y R. Miyamoto; H. Akizawa; T. Nishikawa; T. Uehara; Y. Azuma; I. Nakase; S. Futaki; H. Hanaoka; Y. Iida; K. Endo; Y. Arano Enhanced target-specific accumulation of radiolabeled antibodies by conjugating arginine-rich peptides as anchoring molecules Enhanced target-specific accumulation of radiolabeled antibodies by conjugating arginine-rich peptides as anchoring molecules. Enhanced target-specific accumulation of radiolabeled antibodies by conjugating arginine-rich peptides as anchoring molecules Bioconjugate Chemistry, 21, 11, 2031-2037 Bioconjugate chemistry, 21, 11, 2031-2037 Bioconjugate Chemistry, 21, 11, 2031-2037 2010/11 Refereed English Disclose to all
M. Imanishi; C. Imamura; C. Higashi; W. Yan; S. Negi; S. Futaki; Y. Sugiura Imanishi M, Imamura C, Higashi C, Yan W, Negi S, Futaki S, Sugiura Y M. Imanishi; C. Imamura; C. Higashi; W. Yan; S. Negi; S. Futaki; Y. Sugiura Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1 Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1. Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1 Biochemical and Biophysical Research Communications, 400, 4, 625-630 Biochemical and biophysical research communications, 400, 4, 625-630 Biochemical and Biophysical Research Communications, 400, 4, 625-630 2010/10/01 Refereed English Disclose to all
K. Shimane; E.N. Kodama; I. Nakase; S. Futaki; Y. Sakurai; Y. Sakagami; X. Li; T. Hattori; S.G. Sarafianos; M. Matsuoka Shimane K, Kodama EN, Nakase I, Futaki S, Sakurai Y, Sakagami Y, Li X, Hattori T, Sarafianos SG, Matsuoka M K. Shimane; E.N. Kodama; I. Nakase; S. Futaki; Y. Sakurai; Y. Sakagami; X. Li; T. Hattori; S.G. Sarafianos; M. Matsuoka Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4 Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4. Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4 International Journal of Biochemistry and Cell Biology, 42, 9, 1482-1488 The international journal of biochemistry & cell biology, 42, 9, 1482-1488 International Journal of Biochemistry and Cell Biology, 42, 9, 1482-1488 2010/09 Refereed English Disclose to all
M. Imanishi; T. Nakaya; T. Morisaki; D. Noshiro; S. Futaki; Y. Sugiura Imanishi M, Nakaya T, Morisaki T, Noshiro D, Futaki S, Sugiura Y M. Imanishi; T. Nakaya; T. Morisaki; D. Noshiro; S. Futaki; Y. Sugiura Metal-stimulated regulation of transcription by an artificial zinc-finger protein Metal-stimulated regulation of transcription by an artificial zinc-finger protein. Metal-stimulated regulation of transcription by an artificial zinc-finger protein ChemBioChem, 11, 12, 1653-1655 Chembiochem : a European journal of chemical biology, 11, 12, 1653-1655 ChemBioChem, 11, 12, 1653-1655 2010/08/16 Refereed English Disclose to all
二木史朗, 中瀬生彦 二木史朗, 中瀬生彦 膜透過性塩基性ペプチドを用いる細胞内送達技術 : その分子機構と応用 膜透過性塩基性ペプチドを用いる細胞内送達技術 : その分子機構と応用 生物物理, 50, 3, 137-140 生物物理, 50, 3, 137-140 , 50, 3, 137-140 2010/05/25 Refereed Japanese Disclose to all
H. Akita; K. Kogure; R. Moriguchi; Y. Nakamura; T. Higashi; T. Nakamura; S. Serada; M. Fujimoto; T. Naka; S. Futaki; H. Harashima Akita H, Kogure K, Moriguchi R, Nakamura Y, Higashi T, Nakamura T, Serada S, Fujimoto M, Naka T, Futaki S, Harashima H H. Akita; K. Kogure; R. Moriguchi; Y. Nakamura; T. Higashi; T. Nakamura; S. Serada; M. Fujimoto; T. Naka; S. Futaki; H. Harashima Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: programmed endosomal escape and dissociation. Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation Journal of Controlled Release, 143, 3, 311-317 Journal of controlled release : official journal of the Controlled Release Society, 143, 3, 311-317 Journal of Controlled Release, 143, 3, 311-317 2010/05/10 Refereed English Disclose to all
D. Noshiro; K. Asami; S. Futaki Noshiro D, Asami K, Futaki S D. Noshiro; K. Asami; S. Futaki Metal-assisted channel stabilization: Disposition of a single histidine on the N-terminus of alamethicin yields channels with extraordinarily long lifetimes Metal-assisted channel stabilization: disposition of a single histidine on the N-terminus of alamethicin yields channels with extraordinarily long lifetimes. Metal-assisted channel stabilization: Disposition of a single histidine on the N-terminus of alamethicin yields channels with extraordinarily long lifetimes Biophysical Journal, 98, 9, 1801-1808 Biophysical journal, 98, 9, 1801-1808 Biophysical Journal, 98, 9, 1801-1808 2010/05/05 Refereed English Disclose to all
D. Araki; K. Takayama; M. Inoue; T. Watanabe; H. Kumon; S. Futaki; H. Matsui; K. Tomizawa Araki D, Takayama K, Inoue M, Watanabe T, Kumon H, Futaki S, Matsui H, Tomizawa K D. Araki; K. Takayama; M. Inoue; T. Watanabe; H. Kumon; S. Futaki; H. Matsui; K. Tomizawa Cell-penetrating d-Isomer Peptides of p53 C-terminus: Long-term Inhibitory Effect on the Growth of Bladder Cancer Cell-penetrating D-isomer peptides of p53 C-terminus: long-term inhibitory effect on the growth of bladder cancer. Cell-penetrating d-Isomer Peptides of p53 C-terminus: Long-term Inhibitory Effect on the Growth of Bladder Cancer Urology, 75, 4, 813-819 Urology, 75, 4, 813-819 Urology, 75, 4, 813-819 2010/04 Refereed English Disclose to all
Morisaki Tatsuya, Imanishi Miki, Futaki Shiroh, Sugiura Yukio T. Morisaki; M. Imanishi; S. Futaki; Y. Sugiura Morisaki Tatsuya, Imanishi Miki, Futaki Shiroh, Sugiura Yukio Artificial Transcription Factors Based on Multi-zinc Finger Motifs Artificial transcription factors based on multi-zinc finger motifs Artificial Transcription Factors Based on Multi-zinc Finger Motifs YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 1, 45-48 Yakugaku Zasshi, 130, 1, 45-48 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130, 1, 45-48 2010/01 Refereed Japanese Disclose to all
H. Yukawa; H. Noguchi; I. Nakase; Y. Miyamoto; K. Oishi; N. Hamajima; S. Futaki; S. Hayashi Yukawa H, Noguchi H, Nakase I, Miyamoto Y, Oishi K, Hamajima N, Futaki S, Hayashi S H. Yukawa; H. Noguchi; I. Nakase; Y. Miyamoto; K. Oishi; N. Hamajima; S. Futaki; S. Hayashi Transduction of cell-penetrating peptides into induced pluripotent stem cells Transduction of cell-penetrating peptides into induced pluripotent stem cells. Transduction of cell-penetrating peptides into induced pluripotent stem cells Cell Transplantation, 19, 6, 901-909 Cell transplantation, 19, 6, 901-909 Cell Transplantation, 19, 6, 901-909 2010 Refereed English Disclose to all
I. Nakase; S. Kobayashi; S. Futaki Nakase I, Kobayashi S, Futaki S I. Nakase; S. Kobayashi; S. Futaki Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules. Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules. Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules. Biopolymers, 94, 6, 763-770 Biopolymers, 94, 6, 763-770 Biopolymers, 94, 6, 763-770 2010 Refereed English Disclose to all
C.L. Watkins; P. Brennan; C. Fegan; K. Takayama; I. Nakase; S. Futaki; A.T. Jones Watkins CL, Brennan P, Fegan C, Takayama K, Nakase I, Futaki S, Jones AT C.L. Watkins; P. Brennan; C. Fegan; K. Takayama; I. Nakase; S. Futaki; A.T. Jones Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD. Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD Journal of Controlled Release, 140, 3, 237-244 Journal of controlled release : official journal of the Controlled Release Society, 140, 3, 237-244 Journal of Controlled Release, 140, 3, 237-244 2009/12/16 Refereed English Disclose to all
K. Shiga; K. Takayama; S. Futaki; J.E. Hutti; L.C. Cantley; K. Ueki; Y. Ono; H. Mukai Shiga K, Takayama K, Futaki S, Hutti JE, Cantley LC, Ueki K, Ono Y, Mukai H K. Shiga; K. Takayama; S. Futaki; J.E. Hutti; L.C. Cantley; K. Ueki; Y. Ono; H. Mukai Development of an intracellularly acting inhibitory peptide selective for PKN Development of an intracellularly acting inhibitory peptide selective for PKN. Development of an intracellularly acting inhibitory peptide selective for PKN Biochemical Journal, 425, 2, 445-453 The Biochemical journal, 425, 2, 445-453 Biochemical Journal, 425, 2, 445-453 2009/12 Refereed English Disclose to all
P. Guterstam; F. Madani; H. Hirose; T. Takeuchi; S. Futaki; S. EL Andaloussi; A. Gräslund; Ü. Langel Guterstam P, Madani F, Hirose H, Takeuchi T, Futaki S, El Andaloussi S, Gräslund A, Langel U P. Guterstam; F. Madani; H. Hirose; T. Takeuchi; S. Futaki; S. EL Andaloussi; A. Gräslund; Ü. Langel Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate. Elucidating cell-penetrating peptide mechanisms of action for membrane interaction, cellular uptake, and translocation utilizing the hydrophobic counter-anion pyrenebutyrate Biochimica et Biophysica Acta - Biomembranes, 1788, 12, 2509-2517 Biochimica et biophysica acta, 1788, 12, 2509-2517 Biochimica et Biophysica Acta - Biomembranes, 1788, 12, 2509-2517 2009/12 Refereed English Disclose to all
Futaki Shiroh Futaki Shiroh Futaki Shiroh DYNAMICS IN CELLULAR UPTAKE OF ARGININE-RICH PEPTIDES DYNAMICS IN CELLULAR UPTAKE OF ARGININE-RICH PEPTIDES DYNAMICS IN CELLULAR UPTAKE OF ARGININE-RICH PEPTIDES JOURNAL OF GENE MEDICINE, 11, 12, 1150 JOURNAL OF GENE MEDICINE, 11, 12, 1150 JOURNAL OF GENE MEDICINE, 11, 12, 1150 2009/12 Refereed Disclose to all
二木史朗 二木史朗 身近な「ペプチド」:いのちの基本からくすりまで 身近な「ペプチド」:いのちの基本からくすりまで 海洋化学研究, 22, 2, 65-69 海洋化学研究, 22, 2, 65-69 , 22, 2, 65-69 2009/11/01 Japanese Disclose to all
D. Nakase; S. Futaki Nakase I, Futaki S D. Nakase; S. Futaki Development of membrane-permeable peptide vectors and their internalization mechanisms [Development of membrane-permeable peptide vectors and their internalization mechanisms]. Development of membrane-permeable peptide vectors and their internalization mechanisms Seikagaku, 81, 11, 992-995 Seikagaku. The Journal of Japanese Biochemical Society, 81, 11, 992-995 Seikagaku, 81, 11, 992-995 2009/11 Refereed English Disclose to all
I. Nakase; H. Hirose; G. Tanaka; A. Tadokoro; S. Kobayashi; T. Takeuchi; S. Futaki Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayashi S, Takeuchi T, Futaki S I. Nakase; H. Hirose; G. Tanaka; A. Tadokoro; S. Kobayashi; T. Takeuchi; S. Futaki Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis. Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis Molecular Therapy, 17, 11, 1868-1876 Molecular therapy : the journal of the American Society of Gene Therapy, 17, 11, 1868-1876 Molecular Therapy, 17, 11, 1868-1876 2009/11 Refereed English Disclose to all
H. Hatakeyama; E. Ito; H. Akita; M. Oishi; Y. Nagasaki; S. Futaki; H. Harashima Hatakeyama H, Ito E, Akita H, Oishi M, Nagasaki Y, Futaki S, Harashima H H. Hatakeyama; E. Ito; H. Akita; M. Oishi; Y. Nagasaki; S. Futaki; H. Harashima A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo. A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo Journal of Controlled Release, 139, 2, 127-132 Journal of controlled release : official journal of the Controlled Release Society, 139, 2, 127-132 Journal of Controlled Release, 139, 2, 127-132 2009/10/15 Refereed English Disclose to all
M. Imanishi; A. Nakamura; T. Morisaki; S. Futaki Imanishi M, Nakamura A, Morisaki T, Futaki S M. Imanishi; A. Nakamura; T. Morisaki; S. Futaki Positive and negative cooperativity of modularly assembled zinc fingers Positive and negative cooperativity of modularly assembled zinc fingers. Positive and negative cooperativity of modularly assembled zinc fingers Biochemical and Biophysical Research Communications, 387, 3, 440-443 Biochemical and biophysical research communications, 387, 3, 440-443 Biochemical and Biophysical Research Communications, 387, 3, 440-443 2009/09/25 Refereed English Disclose to all
K. Takayama; I. Nakase; H. Michiue; T. Takeuchi; K. Tomizawa; H. Matsui; S. Futaki Takayama K, Nakase I, Michiue H, Takeuchi T, Tomizawa K, Matsui H, Futaki S K. Takayama; I. Nakase; H. Michiue; T. Takeuchi; K. Tomizawa; H. Matsui; S. Futaki Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas) Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas). Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas) Journal of Controlled Release, 138, 2, 128-133 Journal of controlled release : official journal of the Controlled Release Society, 138, 2, 128-133 Journal of Controlled Release, 138, 2, 128-133 2009/09/01 Refereed English Disclose to all
D. Kurihara; H. Akita; A. Kudo; T. Masuda; S. Futaki; H. Harashima Kurihara D, Akita H, Kudo A, Masuda T, Futaki S, Harashima H D. Kurihara; H. Akita; A. Kudo; T. Masuda; S. Futaki; H. Harashima Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus. Effect of polyethyleneglycol spacer on the binding properties of nuclear localization signal-modified liposomes to isolated nucleus Biological and Pharmaceutical Bulletin, 32, 7, 1303-1306 Biological & pharmaceutical bulletin, 32, 7, 1303-1306 Biological and Pharmaceutical Bulletin, 32, 7, 1303-1306 2009/07 Refereed English Disclose to all
C. Gao; I. Izquierdo-Barba; I. Nakase; S. Futaki; J. Ruan; K. Sakamoto; Y. Sakamoto; K. Kuroda; O. Terasaki; S. Che Gao Chuanbo, Izquierdo-Barba Isabel, Nakase Ikuhiko, Futaki Shiroh, Ruan Juanfang, Sakamoto Kazutami, Sakamoto Yasuhiro, Kuroda Kazuyuki, Terasaki Osamu, Che Shunai C. Gao; I. Izquierdo-Barba; I. Nakase; S. Futaki; J. Ruan; K. Sakamoto; Y. Sakamoto; K. Kuroda; O. Terasaki; S. Che Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector Microporous and Mesoporous Materials, 122, 1-3, 201-207 MICROPOROUS AND MESOPOROUS MATERIALS, 122, 1-3, 201-207 Microporous and Mesoporous Materials, 122, 1-3, 201-207 2009/06/01 Refereed Disclose to all
Hatakeyama Hiroto, Itho Erika, Akita Hidetaka, Oihi Motoi, Nagasaki Yukio, Futaki Shiroh, Harashima Hideyoshi Hatakeyama Hiroto, Itho Erika, Akita Hidetaka, Oihi Motoi, Nagasaki Yukio, Futaki Shiroh, Harashima Hideyoshi Hatakeyama Hiroto, Itho Erika, Akita Hidetaka, Oihi Motoi, Nagasaki Yukio, Futaki Shiroh, Harashima Hideyoshi A pH-Sensitive Fusogenic Peptide Facilitates Endosomal Escape and Greatly Enhanced the Gene Silencing of siRNA-Containing Nanoparticles In Vitro and In Vivo A pH-Sensitive Fusogenic Peptide Facilitates Endosomal Escape and Greatly Enhanced the Gene Silencing of siRNA-Containing Nanoparticles In Vitro and In Vivo A pH-Sensitive Fusogenic Peptide Facilitates Endosomal Escape and Greatly Enhanced the Gene Silencing of siRNA-Containing Nanoparticles In Vitro and In Vivo MOLECULAR THERAPY, 17, S388 MOLECULAR THERAPY, 17, S388 MOLECULAR THERAPY, 17, S388 2009/05 Refereed Disclose to all
S. Kobayashi; I. Nakase; N. Kawabata; H.-H. Yu; S. Pujals; M. Imanishi; E. Giralt; S. Futaki Kobayashi S, Nakase I, Kawabata N, Yu HH, Pujals S, Imanishi M, Giralt E, Futaki S S. Kobayashi; I. Nakase; N. Kawabata; H.-H. Yu; S. Pujals; M. Imanishi; E. Giralt; S. Futaki Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes. Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes Bioconjugate Chemistry, 20, 5, 953-959 Bioconjugate chemistry, 20, 5, 953-959 Bioconjugate Chemistry, 20, 5, 953-959 2009/05 Refereed English Disclose to all
C.L. Watkins; D. Schmaljohann; S. Futaki; A.T. Jones Watkins CL, Schmaljohann D, Futaki S, Jones AT C.L. Watkins; D. Schmaljohann; S. Futaki; A.T. Jones Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide. Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide Biochemical Journal, 420, 2, 179-189 The Biochemical journal, 420, 2, 179-189 Biochemical Journal, 420, 2, 179-189 2009/05 Refereed English Disclose to all
K. Inomata; A. Ohno; H. Tochio; S. Isogai; T. Tenno; I. Nakase; T. Takeuchi; S. Futaki; Y. Ito; H. Hiroaki; M. Shirakawa Inomata K, Ohno A, Tochio H, Isogai S, Tenno T, Nakase I, Takeuchi T, Futaki S, Ito Y, Hiroaki H, Shirakawa M K. Inomata; A. Ohno; H. Tochio; S. Isogai; T. Tenno; I. Nakase; T. Takeuchi; S. Futaki; Y. Ito; H. Hiroaki; M. Shirakawa High-resolution multi-dimensional NMR spectroscopy of proteins in human cells High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. High-resolution multi-dimensional NMR spectroscopy of proteins in human cells Nature, 458, 7234, 106-109 Nature, 458, 7234, 106-109 Nature, 458, 7234, 106-109 2009/03/05 Refereed English Disclose to all
A. El-Sayed; S. Futaki; H. Harashima El-Sayed A, Futaki S, Harashima H A. El-Sayed; S. Futaki; H. Harashima Delivery of macromolecules using arginine-rich cell-penetrating peptides: Ways to overcome endosomal entrapment Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment. Delivery of macromolecules using arginine-rich cell-penetrating peptides: Ways to overcome endosomal entrapment AAPS Journal, 11, 1, 13-22 The AAPS journal, 11, 1, 13-22 AAPS Journal, 11, 1, 13-22 2009/03 Refereed English Disclose to all
I. Nakase; B. Gallis; T. Takatani-Nakase; S. Oh; E. Lacoste; N.P. Singh; D.R. Goodlett; S. Tanaka; S. Futaki; H. Lai; T. Sasaki Nakase I, Gallis B, Takatani-Nakase T, Oh S, Lacoste E, Singh NP, Goodlett DR, Tanaka S, Futaki S, Lai H, Sasaki T I. Nakase; B. Gallis; T. Takatani-Nakase; S. Oh; E. Lacoste; N.P. Singh; D.R. Goodlett; S. Tanaka; S. Futaki; H. Lai; T. Sasaki Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis. Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis Cancer Letters, 274, 2, 290-298 Cancer letters, 274, 2, 290-298 Cancer Letters, 274, 2, 290-298 2009/02/18 Refereed English Disclose to all
K. Takayama; A. Tadokoro; S. Pujals; I. Nakase; E. Giralt; S. Futaki Takayama K, Tadokoro A, Pujals S, Nakase I, Giralt E, Futaki S K. Takayama; A. Tadokoro; S. Pujals; I. Nakase; E. Giralt; S. Futaki Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery. Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery Bioconjugate Chemistry, 20, 2, 249-257 Bioconjugate chemistry, 20, 2, 249-257 Bioconjugate Chemistry, 20, 2, 249-257 2009/02 Refereed English Disclose to all
中瀬生彦, 二木史朗 中瀬生彦, 二木史朗 膜透過ペプチドベクターの開発とメカニズム (Review) 膜透過ペプチドベクターの開発とメカニズム (Review) 生化学, 81(11), 992-995 生化学, 81(11), 992-995 2009 Refereed Japanese Disclose to all
二木史朗 二木史朗 「細胞表面を取り巻く化学」 「細胞表面を取り巻く化学」 化学レビュー10 生体機能化学生体機能の謎に迫る!, 64(3), 48-52 化学レビュー10 生体機能化学生体機能の謎に迫る!, 64(3), 48-52 2009 Japanese Disclose to all
Y. Azuma; M. Imanishi; T. Yoshimura; T. Kawabata; S. Futaki Azuma Y, Imanishi M, Yoshimura T, Kawabata T, Futaki S Y. Azuma; M. Imanishi; T. Yoshimura; T. Kawabata; S. Futaki Cobalt(II)-responsive DNA binding of a GCN4-bZIP protein containing cysteine residues functionalized. with iminodiacetic acid Cobalt(II)-responsive DNA binding of a GCN4-bZIP protein containing cysteine residues functionalized with iminodiacetic acid. Cobalt(II)-responsive DNA binding of a GCN4-bZIP protein containing cysteine residues functionalized. with iminodiacetic acid Angewandte Chemie - International Edition, 48, 37, 6853-6856 Angewandte Chemie (International ed. in English), 48, 37, 6853-6856 Angewandte Chemie - International Edition, 48, 37, 6853-6856 2009 Refereed English Disclose to all
K. Takayama; Y. Suehisa; T. Fujita; J.-T. Nguyen; S. Futaki; A. Yamamoto; Y. Kiso; Y. Hayashi Takayama K, Suehisa Y, Fujita T, Nguyen JT, Futaki S, Yamamoto A, Kiso Y, Hayashi Y K. Takayama; Y. Suehisa; T. Fujita; J.-T. Nguyen; S. Futaki; A. Yamamoto; Y. Kiso; Y. Hayashi Oligoarginine-based prodrugs with self-cleavable spacers for caco-2 cell permeation Oligoarginine-based prodrugs with self-cleavable spacers for caco-2 cell permeation. Oligoarginine-based prodrugs with self-cleavable spacers for caco-2 cell permeation Chemical and Pharmaceutical Bulletin, 56, 11, 1515-1520 Chemical & pharmaceutical bulletin, 56, 11, 1515-1520 Chemical and Pharmaceutical Bulletin, 56, 11, 1515-1520 2008/11 Refereed English Disclose to all
T. Morisaki; M. Imanishi; S. Futaki; Y. Sugiura Morisaki T, Imanishi M, Futaki S, Sugiura Y T. Morisaki; M. Imanishi; S. Futaki; Y. Sugiura Rapid transcriptional activity in vivo and slow DNA binding in vitro by an artificial multi-zinc finger protein Rapid transcriptional activity in vivo and slow DNA binding in vitro by an artificial multi-zinc finger protein. Rapid transcriptional activity in vivo and slow DNA binding in vitro by an artificial multi-zinc finger protein Biochemistry, 47, 38, 10171-10177 Biochemistry, 47, 38, 10171-10177 Biochemistry, 47, 38, 10171-10177 2008/09/23 Refereed English Disclose to all
A. El-Sayed; I.A. Khalil; K. Kogure; S. Futaki; H. Harashima El-Sayed A, Khalil IA, Kogure K, Futaki S, Harashima H A. El-Sayed; I.A. Khalil; K. Kogure; S. Futaki; H. Harashima Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape. Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape Journal of Biological Chemistry, 283, 34, 23450-23461 The Journal of biological chemistry, 283, 34, 23450-23461 Journal of Biological Chemistry, 283, 34, 23450-23461 2008/08/22 Refereed English Disclose to all
Nakase Ikuhiko, Kobayashi Sachiko, Kawabata Noriko, Futaki Shiroh Nakase Ikuhiko, Kobayashi Sachiko, Kawabata Noriko, Futaki Shiroh Nakase Ikuhiko, Kobayashi Sachiko, Kawabata Noriko, Futaki Shiroh Novel intracellular delivery system using pH-dependent fusiogenic peptide Novel intracellular delivery system using pH-dependent fusiogenic peptide Novel intracellular delivery system using pH-dependent fusiogenic peptide JOURNAL OF PEPTIDE SCIENCE, 14, 8, 117 JOURNAL OF PEPTIDE SCIENCE, 14, 8, 117 JOURNAL OF PEPTIDE SCIENCE, 14, 8, 117 2008/08 Refereed Disclose to all
K. Sasaki; K. Kogure; S. Chaki; Y. Nakamura; R. Moriguchi; H. Hamada; R. Danev; K. Nagayama; S. Futaki; H. Harashima Sasaki K, Kogure K, Chaki S, Nakamura Y, Moriguchi R, Hamada H, Danev R, Nagayama K, Futaki S, Harashima H K. Sasaki; K. Kogure; S. Chaki; Y. Nakamura; R. Moriguchi; H. Hamada; R. Danev; K. Nagayama; S. Futaki; H. Harashima An artificial virus-like nano carrier system: Enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives. An artificial virus-like nano carrier system: Enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives Analytical and Bioanalytical Chemistry, 391, 8, 2717-2727 Analytical and bioanalytical chemistry, 391, 8, 2717-2727 Analytical and Bioanalytical Chemistry, 391, 8, 2717-2727 2008/08 Refereed English Disclose to all
I.A. Khalil; K. Kogure; S. Futaki; H. Harashima Khalil IA, Kogure K, Futaki S, Harashima H I.A. Khalil; K. Kogure; S. Futaki; H. Harashima Octaarginine-modified liposomes: Enhanced cellular uptake and controlled intracellular trafficking Octaarginine-modified liposomes: enhanced cellular uptake and controlled intracellular trafficking. Octaarginine-modified liposomes: Enhanced cellular uptake and controlled intracellular trafficking International Journal of Pharmaceutics, 354, 1-2, 39-48 International journal of pharmaceutics, 354, 1-2, 39-48 International Journal of Pharmaceutics, 354, 1-2, 39-48 2008/04/16 Refereed English Disclose to all
二木史朗 二木史朗 膜透過ペプチドを用いる細胞導入技術 膜透過ペプチドを用いる細胞導入技術 ファルマシア, 44, 4, 321-325 ファルマシア, 44, 4, 321-325 , 44, 4, 321-325 2008/04/01 Refereed Japanese Disclose to all
I. Nakase; T. Takeuchi; G. Tanaka; S. Futaki Nakase I, Takeuchi T, Tanaka G, Futaki S I. Nakase; T. Takeuchi; G. Tanaka; S. Futaki Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides Advanced Drug Delivery Reviews, 60, 4-5, 598-607 Advanced drug delivery reviews, 60, 4-5, 598-607 Advanced Drug Delivery Reviews, 60, 4-5, 598-607 2008/03/01 Refereed English Disclose to all
M. Kosuge; T. Takeuchi; I. Nakase; A.T. Jones; S. Futaki Kosuge M, Takeuchi T, Nakase I, Jones AT, Futaki S M. Kosuge; T. Takeuchi; I. Nakase; A.T. Jones; S. Futaki Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans Bioconjugate Chemistry, 19, 3, 656-664 Bioconjugate chemistry, 19, 3, 656-664 Bioconjugate Chemistry, 19, 3, 656-664 2008/03 Refereed English Disclose to all
S. Futaki Futaki S S. Futaki Membrane permeable peptide vectors: chemistry and functional design for the therapeutic applications Membrane permeable peptide vectors: chemistry and functional design for the therapeutic applications. Membrane permeable peptide vectors: chemistry and functional design for the therapeutic applications Advanced Drug Delivery Reviews, 60, 4-5, 447-447 Advanced drug delivery reviews, 60, 4-5, 447-447 Advanced Drug Delivery Reviews, 60, 4-5, 447-447 2008/03 Refereed English Disclose to all
Nakase Ikuhiko, Hirose Hisaaki, Futaki Shiroh Nakase Ikuhiko, Hirose Hisaaki, Futaki Shiroh Nakase Ikuhiko, Hirose Hisaaki, Futaki Shiroh Evaluation of effective membrane penetration by FHV peptide Evaluation of effective membrane penetration by FHV peptide Evaluation of effective membrane penetration by FHV peptide YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 95-96 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 95-96 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 95-96 2008 Refereed Disclose to all
Azuma Yusuke, Yoshimura Tomoyuki, Kawabata Takeo, Futaki Shiroh Azuma Yusuke, Yoshimura Tomoyuki, Kawabata Takeo, Futaki Shiroh Azuma Yusuke, Yoshimura Tomoyuki, Kawabata Takeo, Futaki Shiroh Structural switch of artificial metal-responsive leucine zipper motifs using Ida-Co(II) complexation Structural switch of artificial metal-responsive leucine zipper motifs using Ida-Co(II) complexation Structural switch of artificial metal-responsive leucine zipper motifs using Ida-Co(II) complexation YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 73 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 73 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 73 2008 Refereed Disclose to all
Noshiro Daisuke, Asami Koji, Futaki Shiroh Noshiro Daisuke, Asami Koji, Futaki Shiroh Noshiro Daisuke, Asami Koji, Futaki Shiroh Creation of metal sensitive channel-forming peptides: Metal-assisted peptide assembly and its application Creation of metal sensitive channel-forming peptides: Metal-assisted peptide assembly and its application Creation of metal sensitive channel-forming peptides: Metal-assisted peptide assembly and its application YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 41 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 41 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 41 2008 Refereed Disclose to all
El-Sayed Ayman, Khalil Ikramy A., Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi El-Sayed Ayman, Khalil Ikramy A., Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi El-Sayed Ayman, Khalil Ikramy A., Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi Effect of surface-modification with octaarginine versus octalysine on cellular uptake and endosomal escape of nanoparticles Effect of surface-modification with octaarginine versus octalysine on cellular uptake and endosomal escape of nanoparticles Effect of surface-modification with octaarginine versus octalysine on cellular uptake and endosomal escape of nanoparticles YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 111-112 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 111-112 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128, 111-112 2008 Refereed Disclose to all
Y. Hayashi; K. Takayama; Y. Suehisa; T. Fujita; J.-T. Nguyen; S. Futaki; A. Yamamoto; Y. Kiso Hayashi Y, Takayama K, Suehisa Y, Fujita T, Nguyen JT, Futaki S, Yamamoto A, Kiso Y Y. Hayashi; K. Takayama; Y. Suehisa; T. Fujita; J.-T. Nguyen; S. Futaki; A. Yamamoto; Y. Kiso Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers toward effective intestinal absorption Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers toward effective intestinal absorption. Development of oligoarginine-drug conjugates linked to new peptidic self-cleavable spacers toward effective intestinal absorption Bioorganic and Medicinal Chemistry Letters, 17, 18, 5129-5132 Bioorganic & medicinal chemistry letters, 17, 18, 5129-5132 Bioorganic and Medicinal Chemistry Letters, 17, 18, 5129-5132 2007/09/15 Refereed English Disclose to all
W. Yan; M. Imanishi; S. Futaki; Y. Sugiura Yan W, Imanishi M, Futaki S, Sugiura Y W. Yan; M. Imanishi; S. Futaki; Y. Sugiura α-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence Alpha-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence. α-helical linker of an artificial 6-zinc finger peptide contributes to selective DNA binding to a discontinuous recognition sequence Biochemistry, 46, 29, 8517-8524 Biochemistry, 46, 29, 8517-8524 Biochemistry, 46, 29, 8517-8524 2007/07/24 Refereed English Disclose to all
A. Homhuan; K. Kogure; H. Akaza; S. Futaki; T. Naka; Y. Fujita; I. Yano; H. Harashima Homhuan A, Kogure K, Akaza H, Futaki S, Naka T, Fujita Y, Yano I, Harashima H A. Homhuan; K. Kogure; H. Akaza; S. Futaki; T. Naka; Y. Fujita; I. Yano; H. Harashima New packaging method of mycobacterial cell wall using octaarginine-modified liposomes: Enhanced uptake by and immunostimulatory activity of dendritic cells New packaging method of mycobacterial cell wall using octaarginine-modified liposomes: enhanced uptake by and immunostimulatory activity of dendritic cells. New packaging method of mycobacterial cell wall using octaarginine-modified liposomes: Enhanced uptake by and immunostimulatory activity of dendritic cells Journal of Controlled Release, 120, 1-2, 60-69 Journal of controlled release : official journal of the Controlled Release Society, 120, 1-2, 60-69 Journal of Controlled Release, 120, 1-2, 60-69 2007/07/13 Refereed English Disclose to all
Y. Nakamura; K. Kogure; S. Futaki; H. Harashima Nakamura Y, Kogure K, Futaki S, Harashima H Y. Nakamura; K. Kogure; S. Futaki; H. Harashima Octaarginine-modified multifunctional envelope-type nano device for siRNA Octaarginine-modified multifunctional envelope-type nano device for siRNA. Octaarginine-modified multifunctional envelope-type nano device for siRNA Journal of Controlled Release, 119, 3, 360-367 Journal of controlled release : official journal of the Controlled Release Society, 119, 3, 360-367 Journal of Controlled Release, 119, 3, 360-367 2007/06/22 Refereed English Disclose to all
S. Futaki; K. Asami Futaki S, Asami K S. Futaki; K. Asami Ligand-induced extramembrane conformation switch controlling alamethicin assembly and the channel current Ligand-induced extramembrane conformation switch controlling alamethicin assembly and the channel current. Ligand-induced extramembrane conformation switch controlling alamethicin assembly and the channel current Chemistry and Biodiversity, 4, 6, 1313-1322 Chemistry & biodiversity, 4, 6, 1313-1322 Chemistry and Biodiversity, 4, 6, 1313-1322 2007/06 Refereed English Disclose to all
M.M. Fretz; N.A. Penning; S. Al-Taei; S. Futaki; T. Takeuchi; I. Nakase; G. Storm; A.T. Jones Fretz Marjan M., Penning Neal A., Al-Taei Saly, Futaki Shiroh, Takeuchi Toshihide, Nakase Ikuhiko, Storm Gert, Jones Arwyn T. M.M. Fretz; N.A. Penning; S. Al-Taei; S. Futaki; T. Takeuchi; I. Nakase; G. Storm; A.T. Jones Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34<sup>+</sup> leukaemia cells Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34(+) leukaemia cells Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34<sup>+</sup> leukaemia cells Biochemical Journal, 403, 2, 335-342 BIOCHEMICAL JOURNAL, 403, 2, 335-342 Biochemical Journal, 403, 2, 335-342 2007/04/15 Refereed Disclose to all
T. Kimura; K. Ninomiya; S. Futaki Kimura T, Ninomiya K, Futaki S T. Kimura; K. Ninomiya; S. Futaki NMR investigation of the electrostatic effect in binding of a neuropeptide, achatin-I, to phosphatidylcholine bilayers NMR investigation of the electrostatic effect in binding of a neuropeptide, achatin-I, to phosphatidylcholine bilayers. NMR investigation of the electrostatic effect in binding of a neuropeptide, achatin-I, to phosphatidylcholine bilayers Journal of Physical Chemistry B, 111, 14, 3831-3838 The journal of physical chemistry. B, 111, 14, 3831-3838 Journal of Physical Chemistry B, 111, 14, 3831-3838 2007/04/12 Refereed English Disclose to all
I. Nakase; A. Tadokoro; N. Kawabata; T. Takeuchi; H. Katoh; K. Hiramoto; M. Negishi; M. Nomizu; Y. Sugiura; S. Futaki Nakase Ikuhiko, Tadokoro Akiko, Kawabata Noriko, Takeuchi Toshihide, Katoh Hironori, Hiramoto Kiyo, Negishi Manabu, Nomizu Motoyoshi, Sugiura Yukio, Futaki Shiroh I. Nakase; A. Tadokoro; N. Kawabata; T. Takeuchi; H. Katoh; K. Hiramoto; M. Negishi; M. Nomizu; Y. Sugiura; S. Futaki Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis Biochemistry, 46, 2, 492-501 BIOCHEMISTRY, 46, 2, 492-501 Biochemistry, 46, 2, 492-501 2007/01/16 Refereed Disclose to all
K.K. Maiti; W.S. Lee; T. Takeuchi; C. Watkins; M. Fretz; D.-C. Kim; S. Futaki; A. Jones; K.-T. Kim; S.-K. Chung Maiti KK, Lee WS, Takeuchi T, Watkins C, Fretz M, Kim DC, Futaki S, Jones A, Kim KT, Chung SK K.K. Maiti; W.S. Lee; T. Takeuchi; C. Watkins; M. Fretz; D.-C. Kim; S. Futaki; A. Jones; K.-T. Kim; S.-K. Chung Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria Guanidine-containing molecular transporters: sorbitol-based transporters show high intracellular selectivity toward mitochondria. Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria Angewandte Chemie - International Edition, 46, 31, 5880-5884 Angewandte Chemie (International ed. in English), 46, 31, 5880-5884 Angewandte Chemie - International Edition, 46, 31, 5880-5884 2007 Refereed English Disclose to all
S. Kameyama; M. Horie; T. Kikuchi; T. Omura; A. Tadokoro; T. Takeuchi; I. Nakase; Y. Sugiura; S. Futaki Kameyama Shouju, Horie Mayo, Kikuchi Takeo, Omura Takao, Tadokoro Akiko, Takeuchi Toshihide, Nakase Ikuhiko, Sugiura Yukio, Futaki Shiroh S. Kameyama; M. Horie; T. Kikuchi; T. Omura; A. Tadokoro; T. Takeuchi; I. Nakase; Y. Sugiura; S. Futaki Acid wash in determining cellular uptake of fab/cell-permeating peptide conjugates Acid wash in determining cellular uptake of fab/cell-permeating peptide conjugates Acid wash in determining cellular uptake of fab/cell-permeating peptide conjugates Biopolymers - Peptide Science Section, 88, 2, 98-107 BIOPOLYMERS, 88, 2, 98-107 Biopolymers - Peptide Science Section, 88, 2, 98-107 2007 Refereed Disclose to all
Y. Otani; S. Futaki; T. Kiwada; Y. Sugiura; A. Muranaka; N. Kobayashi; M. Uchiyama; K. Yamaguchi; T. Ohwada Otani Yuko, Futaki Shiroh, Kiwada Tatsuto, Sugiura Yukio, Muranaka Atsuya, Kobayashi Nagao, Uchiyama Masanobu, Yamaguchi Kentaro, Ohwada Tomohiko Y. Otani; S. Futaki; T. Kiwada; Y. Sugiura; A. Muranaka; N. Kobayashi; M. Uchiyama; K. Yamaguchi; T. Ohwada Oligomers of β-amino acid bearing non-planar amides form ordered structures Oligomers of beta-amino acid bearing non-planar amides form ordered structures Oligomers of β-amino acid bearing non-planar amides form ordered structures Tetrahedron, 62, 50, 11635-11644 TETRAHEDRON, 62, 50, 11635-11644 Tetrahedron, 62, 50, 11635-11644 2006/12/11 Refereed Disclose to all
M. Fretz; J. Jin; R. Conibere; N.A. Penning; S. Al-Taei; G. Storm; S. Futaki; T. Takeuchi; I. Nakase; A.T. Jones Fretz Marjan, Jin Jing, Conibere Robin, Penning Neal A., Al-Taei Saly, Storm Gert, Futaki Shiroh, Takeuchi Toshihide, Nakase Ikuhiko, Jones Arwyn T. M. Fretz; J. Jin; R. Conibere; N.A. Penning; S. Al-Taei; G. Storm; S. Futaki; T. Takeuchi; I. Nakase; A.T. Jones Effects of Na<sup>+</sup>/H<sup>+</sup> exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine Effects of Na<sup>+</sup>/H<sup>+</sup> exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine Journal of Controlled Release, 116, 2, 247-254 JOURNAL OF CONTROLLED RELEASE, 116, 2, 247-254 Journal of Controlled Release, 116, 2, 247-254 2006/11/28 Refereed Disclose to all
N. Sakai; S. Futaki; S. Matile Sakai Naomi, Futaki Shiroh, Matile Stefan N. Sakai; S. Futaki; S. Matile Anion hopping of (and on) functional oligoarginines: From chloroform to cells Anion hopping of (and on) functional oligoarginines: from chloroform to cells Anion hopping of (and on) functional oligoarginines: From chloroform to cells Soft Matter, 2, 8, 636-641 SOFT MATTER, 2, 8, 636-641 Soft Matter, 2, 8, 636-641 2006/08/07 Refereed Disclose to all
T. Nakamura; R. Moriguchi; K. Kogure; A. Minoura; T. Masuda; H. Akita; K. Kato; H. Hamada; M. Ueno; S. Futaki; H. Harashima Nakamura Takashi, Moriguchi Rumiko, Kogure Kentaro, Minoura Arisa, Masuda Tomoya, Akita Hidetaka, Kato Kazunori, Hamada Hirofumi, Futaki Shiroh, Harashima Hideyoshi T. Nakamura; R. Moriguchi; K. Kogure; A. Minoura; T. Masuda; H. Akita; K. Kato; H. Hamada; M. Ueno; S. Futaki; H. Harashima Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells Biological and Pharmaceutical Bulletin, 29, 6, 1290-1293 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 29, 6, 1290-1293 Biological and Pharmaceutical Bulletin, 29, 6, 1290-1293 2006/06 Refereed Disclose to all
A. Iwasa; H. Akita; I. Khalil; K. Kogure; S. Futaki; H. Harashima Iwasa Akitada, Akita Hidetaka, Khalil Ikramy, Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi A. Iwasa; H. Akita; I. Khalil; K. Kogure; S. Futaki; H. Harashima Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature Biochimica et Biophysica Acta - Biomembranes, 1758, 6, 713-720 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1758, 6, 713-720 Biochimica et Biophysica Acta - Biomembranes, 1758, 6, 713-720 2006/06 Refereed Disclose to all
T. Kiwada; K. Sonomura; Y. Sugiura; K. Asami; S. Futaki Kiwada Tatsuto, Sonomura Kazuhiro, Sugiura Yukio, Asami Koji, Futaki Shiroh T. Kiwada; K. Sonomura; Y. Sugiura; K. Asami; S. Futaki Transmission of extramembrane conformational change into current: Construction of metal-gated ion channel Transmission of extramembrane conformational change into current: Construction of metal-gated ion channel Transmission of extramembrane conformational change into current: Construction of metal-gated ion channel Journal of the American Chemical Society, 128, 18, 6010-6011 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128, 18, 6010-6011 Journal of the American Chemical Society, 128, 18, 6010-6011 2006/05/10 Refereed Disclose to all
Iwasa Akitada, Akita Hidetaka, Khalil Ikramy, Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi Iwasa Akitada, Akita Hidetaka, Khalil Ikramy, Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi Iwasa Akitada, Akita Hidetaka, Khalil Ikramy, Kogure Kentaro, Futaki Shiroh, Harashima Hideyoshi Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature MOLECULAR THERAPY, 13, S129 MOLECULAR THERAPY, 13, S129 MOLECULAR THERAPY, 13, S129 2006/05 Refereed Disclose to all
Kogure Kentaro, Nakamura Yoshio, Khalil Ikramy A., Futaki Shiroh, Harashima Hideyoshi Kogure Kentaro, Nakamura Yoshio, Khalil Ikramy A., Futaki Shiroh, Harashima Hideyoshi Kogure Kentaro, Nakamura Yoshio, Khalil Ikramy A., Futaki Shiroh, Harashima Hideyoshi Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA MOLECULAR THERAPY, 13, S202-S203 MOLECULAR THERAPY, 13, S202-S203 MOLECULAR THERAPY, 13, S202-S203 2006/05 Refereed Disclose to all
S. Kameyama; R. Okada; T. Kikuchi; T. Omura; I. Nakase; T. Takeuchi; Y. Sugiura; S. Futaki Kameyama Shouju, Okada Ritsuko, Kikuchi Takeo, Ornura Takao, Nakase Ikuhiko, Takeuchi Toshihide, Sugiura Yukio, Futaki Shiroh S. Kameyama; R. Okada; T. Kikuchi; T. Omura; I. Nakase; T. Takeuchi; Y. Sugiura; S. Futaki Distribution of immunoglobulin Fab fragment conjugated with HIV-1 REV peptide following intravenous administration in rats Distribution of immunoglobulin Fab fragment conjugated with HIV-1 REV peptide following intravenous administration in rats Distribution of immunoglobulin Fab fragment conjugated with HIV-1 REV peptide following intravenous administration in rats Molecular Pharmaceutics, 3, 2, 174-180 MOLECULAR PHARMACEUTICS, 3, 2, 174-180 Molecular Pharmaceutics, 3, 2, 174-180 2006/03 Refereed Disclose to all
Futaki Shiroh Futaki Shiroh Futaki Shiroh Design of Intracellular Delivery Using Peptide Vectors Design of Intracellular Delivery Using Peptide Vectors Design of Intracellular Delivery Using Peptide Vectors Kobunshi, 55, 345 Kobunshi, 55, 345 Kobunshi, 55, 345 2006/01/01 Disclose to all
K.K. Maiti; O.-Y. Jeon; W.S. Lee; D.-C. Kim; K.-T. Kim; T. Takeuchi; S. Futaki; S.-K. Chung Maiti Kaustabh K., Jeon Ock-Youm, Lee Woo Sirl, Kim Dong-Chan, Kim Kyong-Tai, Takeuchi Toshihide, Futaki Shiroh, Chung Sung-Kee K.K. Maiti; O.-Y. Jeon; W.S. Lee; D.-C. Kim; K.-T. Kim; T. Takeuchi; S. Futaki; S.-K. Chung Design, synthesis, and membrane-translocation studies of inositol-based transporters Design, synthesis, and membrane-translocation studies of inositol-based transporters Design, synthesis, and membrane-translocation studies of inositol-based transporters Angewandte Chemie - International Edition, 45, 18, 2907-2912 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45, 18, 2907-2912 Angewandte Chemie - International Edition, 45, 18, 2907-2912 2006 Refereed Disclose to all
二木史朗 二木史朗 分子集合体の細胞内デリバリー 分子集合体の細胞内デリバリー 臨床検査, 50, 1439-1546 臨床検査, 50, 1439-1546 2006 Refereed Japanese Disclose to all
二木史朗 二木史朗 トピックス:ペプチドベクターを用いた細胞内移送 トピックス:ペプチドベクターを用いた細胞内移送 酵素工学ニュース第55号, 平成18年4月号, 41497 酵素工学ニュース第55号, 平成18年4月号, 41497 2006 Japanese Disclose to all
Futaki Shiroh, Nakase Ikuhiko, Takeuchi Toshihide, Niwa Miki, Simpson Jeremy C., Jones Arwyn T., Sugiura Yukio Futaki Shiroh, Nakase Ikuhiko, Takeuchi Toshihide, Niwa Miki, Simpson Jeremy C., Jones Arwyn T., Sugiura Yukio Futaki Shiroh, Nakase Ikuhiko, Takeuchi Toshihide, Niwa Miki, Simpson Jeremy C., Jones Arwyn T., Sugiura Yukio Arginine-rich peptides: the structures and manners of internalization Arginine-rich peptides: the structures and manners of internalization Arginine-rich peptides: the structures and manners of internalization Peptides 2004, Proceedings, 543-544 Peptides 2004, Proceedings, 543-544 Peptides 2004, Proceedings, 543-544 2005 Refereed Disclose to all
中瀬生彦;二木史朗 中瀬生彦;二木史朗 アルギニンペプチドを用いたタンパク質および薬物の細胞内送達 アルギニンペプチドを用いたタンパク質および薬物の細胞内送達 化学, 59, 11, 68-69 化学, 59, 11, 68-69 , 59, 11, 68-69 2004/11/01 Japanese Disclose to all
二木史朗 二木史朗 DDSの新しい潮流(2)ペプチドを用いた細胞内デリバリー DDSの新しい潮流(2)ペプチドを用いた細胞内デリバリー Drug Metab Pharmacokinet, 19, 4, 18-20 Drug Metab Pharmacokinet, 19, 4, 18-20 , 19, 4, 18-20 2004/08/30 Japanese Disclose to all
二木史朗 二木史朗 キャリヤーペプチドを使ってタンパク質やさまざまな分子を細胞に導入できる! キャリヤーペプチドを使ってタンパク質やさまざまな分子を細胞に導入できる! 現代化学, 401, 32-36 現代化学, 401, 32-36 , 401, 32-36 2004/08/01 Japanese Disclose to all
二木史朗 二木史朗 アルギニンペプチドによる細胞内デリバリー アルギニンペプチドによる細胞内デリバリー 薬剤学, 64, 3, 164-167 薬剤学, 64, 3, 164-167 , 64, 3, 164-167 2004/05/01 Japanese Disclose to all
Futaki Shiroh, Nakase Ikuhiko, Niwa Miki, Suzuki Tomoki, Nameki Daisuke, Kodama Ei-ichi, Matsuoka Masao, Sugiura Yukio Futaki Shiroh, Nakase Ikuhiko, Niwa Miki, Suzuki Tomoki, Nameki Daisuke, Kodama Ei-ichi, Matsuoka Masao, Sugiura Yukio Futaki Shiroh, Nakase Ikuhiko, Niwa Miki, Suzuki Tomoki, Nameki Daisuke, Kodama Ei-ichi, Matsuoka Masao, Sugiura Yukio Application of oligoarginine for the delivery of protein complexes into living cells Application of oligoarginine for the delivery of protein complexes into living cells Application of oligoarginine for the delivery of protein complexes into living cells Peptide Revolution: Genomics, Proteomics & Therapeutics, 791-792 Peptide Revolution: Genomics, Proteomics & Therapeutics, 791-792 Peptide Revolution: Genomics, Proteomics & Therapeutics, 791-792 2004 Refereed Disclose to all
二木史朗 二木史朗 ペプチドによるドラッグデリバリー (Review) ペプチドによるドラッグデリバリー (Review) 細胞, 36, 428-431 細胞, 36, 428-431 2004 Japanese Disclose to all
二木史朗 二木史朗 Membrane permeable basic peptides: The potential of these peptides for the intracellular delivery of proteins and drugs. Membrane permeable basic peptides: The potential of these peptides for the intracellular delivery of proteins and drugs. 蛋白質 核酸 酵素, 47, 11, 1415-1419 蛋白質 核酸 酵素, 47, 11, 1415-1419 , 47, 11, 1415-1419 2002/09/01 Refereed Japanese Disclose to all
民谷栄一;二木史朗;吉田和哉 民谷栄一;二木史朗;吉田和哉 コンビナトリアル・バイオエンジニアリング (6)  バイオテクノロジーのニューウェーブ  コンビナトリアル・バイオエンジニアリングの向かう未来 コンビナトリアル・バイオエンジニアリング (6)  バイオテクノロジーのニューウェーブ  コンビナトリアル・バイオエンジニアリングの向かう未来 現代化学, 372, 23-30 現代化学, 372, 23-30 , 372, 23-30 2002/03/01 Refereed Japanese Disclose to all
二木史朗 二木史朗 チャネルポアの微細加工とリアルタイムセンシング チャネルポアの微細加工とリアルタイムセンシング 化学, 3月号, 58-59 化学, 3月号, 58-59 2001 Japanese Disclose to all
Hiroshi Monoi, Hiroshi Monoi, Hiroshi Monoi, Shiroh Futaki, Shin Ichi Kugimiya, Hiroyuki Minakata, Kazuo Yoshihara Hiroshi Monoi, Hiroshi Monoi, Hiroshi Monoi, Shiroh Futaki, Shin Ichi Kugimiya, Hiroyuki Minakata, Kazuo Yoshihara Hiroshi Monoi, Hiroshi Monoi, Hiroshi Monoi, Shiroh Futaki, Shin Ichi Kugimiya, Hiroyuki Minakata, Kazuo Yoshihara Poly-L-glutamine forms cation channels: Relevance to the pathogenesis of the polyglutamine diseases Poly-L-glutamine forms cation channels: Relevance to the pathogenesis of the polyglutamine diseases Poly-L-glutamine forms cation channels: Relevance to the pathogenesis of the polyglutamine diseases Biophysical Journal, 78, 2892-2899 Biophysical Journal, 78, 2892-2899 Biophysical Journal, 78, 2892-2899 2000/01/01 Disclose to all
二木史朗, 北川幸己, 矢上 健, 山口 実 二木史朗, 北川幸己, 矢上 健, 山口 実 Fmoc固相合成法による硫酸化チロシン含有ペプチドの直接合成法の開発 Fmoc固相合成法による硫酸化チロシン含有ペプチドの直接合成法の開発 島津評論, 56, 1, 67-70 島津評論, 56, 1, 67-70 , 56, 1, 67-70 1999/08 Japanese Disclose to all
K. Kitagawa; N. Mizobuchi; T. Hama; T. Hibi; R. Konishi; S. Futaki Kouki Kitagawa, Noriko Mizobuchi, Teruo Hama, Tohru Hibi, Tohru Hibi, Ryoji Konishi, Shiroh Futaki K. Kitagawa; N. Mizobuchi; T. Hama; T. Hibi; R. Konishi; S. Futaki Synthesis and antinociceptive activity of [D-Ala<sup>2</sup>]Leu-enkephalin derivatives conjugated with the adamantane moiety Synthesis and antinociceptive activity of [D-Ala<sup>2</sup>]Leu-enkephalin derivatives conjugated with the adamantane moiety Synthesis and antinociceptive activity of [D-Ala<sup>2</sup>]Leu-enkephalin derivatives conjugated with the adamantane moiety Chemical and Pharmaceutical Bulletin, 45, 11, 1782-1787 Chemical and Pharmaceutical Bulletin, 45, 11, 1782-1787 Chemical and Pharmaceutical Bulletin, 45, 11, 1782-1787 1997/11 Refereed English Disclose to all
Y. Niwa; M. Yano; S. Futaki; Y. Okumura; H. Kido Yasuharu Niwa, Mihiro Yano, Shiroh Futaki, Yuushi Okumura, Hiroshi Kido, Hiroshi Kido Y. Niwa; M. Yano; S. Futaki; Y. Okumura; H. Kido T-cell membrane-associated serine protease, tryptase TL<sub>2</sub>, binds human immunodeficiency virus type 1 gp120 and cleaves the third-variable-domain loop of gp120 Neutralizing antibodies of human immunodeficiency virus type 1 inhibit cleavage of gp1 T-cell membrane-associated serine protease, tryptase TL<inf>2</inf>, binds human immunodeficiency virus type 1 gp120 and cleaves the third-variable-domain loop of gp120 Neutralizing antibodies of human immunodeficiency virus type 1 inhibit cleavage of gp1 T-cell membrane-associated serine protease, tryptase TL<sub>2</sub>, binds human immunodeficiency virus type 1 gp120 and cleaves the third-variable-domain loop of gp120 Neutralizing antibodies of human immunodeficiency virus type 1 inhibit cleavage of gp1 European Journal of Biochemistry, 237, 1, 64-70 European Journal of Biochemistry, 237, 1, 64-70 European Journal of Biochemistry, 237, 1, 64-70 1996/04 Refereed English Disclose to all
Hiromichi Yokoi, Yoshihiro Tsuruo, Tadayuki Miyamoto, Kouki Kitagawa, Shiroh Futaki, Kazunori Ishimura Hiromichi Yokoi, Yoshihiro Tsuruo, Tadayuki Miyamoto, Kouki Kitagawa, Shiroh Futaki, Kazunori Ishimura Hiromichi Yokoi, Yoshihiro Tsuruo, Tadayuki Miyamoto, Kouki Kitagawa, Shiroh Futaki, Kazunori Ishimura Steroid 5α-reductase type 1 immunolocalized in the anterior pituitary of intact and castrated male rats Steroid 5α-reductase type 1 immunolocalized in the anterior pituitary of intact and castrated male rats Steroid 5α-reductase type 1 immunolocalized in the anterior pituitary of intact and castrated male rats Histochemistry and Cell Biology, 106, 359-366 Histochemistry and Cell Biology, 106, 359-366 Histochemistry and Cell Biology, 106, 359-366 1996/01/01 Disclose to all
KITAGAWA, K; FUTAKI, S; YAGAMI, T Kouki Kitagawa, Shiroh Futaki, Takeshi Yagami KITAGAWA, K; FUTAKI, S; YAGAMI, T A NOVEL-APPROACH FOR THE SYNTHESIS OF TYROSINE SULFATE-CONTAINING PEPTIDES USING A SAFETY CATCH TYPE PROTECTING GROUP AS A KEY FEATURE A Novel Approach for the Synthesis of Tyrosine-Sulfate-Containing Peptides Using a “Safety-Catch”-Type Protecting Group as a Key Feature A NOVEL-APPROACH FOR THE SYNTHESIS OF TYROSINE SULFATE-CONTAINING PEPTIDES USING A SAFETY CATCH TYPE PROTECTING GROUP AS A KEY FEATURE JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 52, 8, 675-685 Journal of Synthetic Organic Chemistry, Japan, 52, 8, 675-685 JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 52, 8, 675-685 1994/08 Refereed English Disclose to all
M. Kamada, N. Maeda, M. Maegawa, H. Mori, S. Yamamoto, T. Aono, M. Muraguchi, Y. Ohmoto, S. Futaki, F. Ogushi, S. Sone, H. Kanayama, S. Kagawa, S. S. Koide M. Kamada, N. Maeda, M. Maegawa, H. Mori, S. Yamamoto, T. Aono, M. Muraguchi, Y. Ohmoto, S. Futaki, F. Ogushi, S. Sone, H. Kanayama, S. Kagawa, S. S. Koide M. Kamada, N. Maeda, M. Maegawa, H. Mori, S. Yamamoto, T. Aono, M. Muraguchi, Y. Ohmoto, S. Futaki, F. Ogushi, S. Sone, H. Kanayama, S. Kagawa, S. S. Koide Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies Biochemistry and Molecular Biology International, 34, 837-844 Biochemistry and Molecular Biology International, 34, 837-844 Biochemistry and Molecular Biology International, 34, 837-844 1994/01/01 Disclose to all
KOUKI KITAGAWAI, SHIROH FCTAKI, TAKESHI YAGAMI, SHOICHIRO SUMI, KAZUTOMO INOUE KOUKI KITAGAWAI, SHIROH FCTAKI, TAKESHI YAGAMI, SHOICHIRO SUMI, KAZUTOMO INOUE KOUKI KITAGAWAI, SHIROH FCTAKI, TAKESHI YAGAMI, SHOICHIRO SUMI, KAZUTOMO INOUE Solid‐phase synthesis of cionin, a protochordate‐derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono‐tyrosine‐sulfate‐containing derivatives Solid‐phase synthesis of cionin, a protochordate‐derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono‐tyrosine‐sulfate‐containing derivatives Solid‐phase synthesis of cionin, a protochordate‐derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono‐tyrosine‐sulfate‐containing derivatives International Journal of Peptide and Protein Research, 43, 190-200 International Journal of Peptide and Protein Research, 43, 190-200 International Journal of Peptide and Protein Research, 43, 190-200 1994/01/01 Disclose to all
OWHASHI, M; FUTAKI, S; KITAGAWA, K; HORII, Y; MARUYAMA, H; HAYASHI, H; NAWA, Y Owhashi Makoto, Futaki Shiroh, Kitagawa Kouki, Horii Yoichiro, Maruyama Haruhiko, Hayashi Hiromi, Nawa Yukifumi OWHASHI, M; FUTAKI, S; KITAGAWA, K; HORII, Y; MARUYAMA, H; HAYASHI, H; NAWA, Y MOLECULAR-CLONING AND CHARACTERIZATION OF A NOVEL NEUTROPHIL CHEMOTACTIC FACTOR FROM A FILARIAL PARASITE Molecular cloning and characterization of a novel neutrophil chemotactic factor from a filarial parasite MOLECULAR-CLONING AND CHARACTERIZATION OF A NOVEL NEUTROPHIL CHEMOTACTIC FACTOR FROM A FILARIAL PARASITE MOLECULAR IMMUNOLOGY, 30, 14, 1315-1320 Molecular Immunology, 30, 14, 1315-1320 MOLECULAR IMMUNOLOGY, 30, 14, 1315-1320 1993/10 Refereed English Disclose to all
T. Yagami; S. Shiwa; S. Futaki; K. Kitagawa Takeshi Yagami, Satoshi Shiwa, Shiroh Futaki, Kouki Kitagawa T. Yagami; S. Shiwa; S. Futaki; K. Kitagawa Evaluation of the final deprotection system for the solid-phase synthesis of tyr(SO<sub>3</sub>H)-containing peptides with 9-fluorenylmethyloxycarbonyl (Fmoc)-strategy and its application to the synthesis of cholecystokinin (CCK)-12 Evaluation of the Final Deprotection System for the Solid-Phase Synthesis of Tyr(SO<inf>3</inf> H)-Containing PeptiDes with 9-Fluorenylmethyloxycarbonyl (Fmoc)-Strategy and Its Application to the Synthesis of Cholecystokinin (CCK)-12<sup>1)</sup> Evaluation of the final deprotection system for the solid-phase synthesis of tyr(SO<sub>3</sub>H)-containing peptides with 9-fluorenylmethyloxycarbonyl (Fmoc)-strategy and its application to the synthesis of cholecystokinin (CCK)-12 Chemical and Pharmaceutical Bulletin, 41, 2, 376-380 Chemical and Pharmaceutical Bulletin, 41, 2, 376-380 Chemical and Pharmaceutical Bulletin, 41, 2, 376-380 1993/02 Refereed English Disclose to all
M. B. Bhatia, S. Futaki, H. Ueno, J. M. Manning, D. Ringe, T. Yoshimura, K. Soda M. B. Bhatia, S. Futaki, H. Ueno, J. M. Manning, D. Ringe, T. Yoshimura, K. Soda M. B. Bhatia, S. Futaki, H. Ueno, J. M. Manning, D. Ringe, T. Yoshimura, K. Soda Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase Journal of Biological Chemistry, 268, 6932-6938 Journal of Biological Chemistry, 268, 6932-6938 Journal of Biological Chemistry, 268, 6932-6938 1993/01/01 Disclose to all
N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide Immunoglobulin binding factor in human seminal plasma: Immunological function Immunoglobulin binding factor in human seminal plasma: Immunological function Immunoglobulin binding factor in human seminal plasma: Immunological function Archives of Andrology, 31, 31-36 Archives of Andrology, 31, 31-36 Archives of Andrology, 31, 31-36 1993/01/01 Disclose to all
N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide N. Maeda, M. Kamada, T. Daitoh, T. Aono, S. Futaki, Z. G. Liang, S. S. Koide Immunoglobulin binding factor in human seminal plasma: Immunological function Immunoglobulin binding factor in human seminal plasma: Immunological function Immunoglobulin binding factor in human seminal plasma: Immunological function Systems Biology in Reproductive Medicine, 31, 31-36 Systems Biology in Reproductive Medicine, 31, 31-36 Systems Biology in Reproductive Medicine, 31, 31-36 1993/01/01 Disclose to all
Shiroh Futaki, Takashi Taike, Takeshi Yagami, Toyoko Ogawa, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takashi Taike, Takeshi Yagami, Toyoko Ogawa, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takashi Taike, Takeshi Yagami, Toyoko Ogawa, Tadashi Akita, Kouki Kitagawa Use of dimethylformamide-sulphur trioxide complex as a sulphating agent of tyrosine Use of dimethylformamide-sulphur trioxide complex as a sulphating agent of tyrosine Use of dimethylformamide-sulphur trioxide complex as a sulphating agent of tyrosine Journal of the Chemical Society, Perkin Transactions 1, 1739-1744 Journal of the Chemical Society, Perkin Transactions 1, 1739-1744 Journal of the Chemical Society, Perkin Transactions 1, 1739-1744 1990/12/01 Disclose to all
S. Futaki, H. Ueno, A. Martinez del Pozo, M. A. Pospischil, J. M. Manning, D. Ringe, B. Stoddard, K. Tanizawa, T. Yoshimura, K. Soda S. Futaki, H. Ueno, A. Martinez del Pozo, M. A. Pospischil, J. M. Manning, D. Ringe, B. Stoddard, K. Tanizawa, T. Yoshimura, K. Soda S. Futaki, H. Ueno, A. Martinez del Pozo, M. A. Pospischil, J. M. Manning, D. Ringe, B. Stoddard, K. Tanizawa, T. Yoshimura, K. Soda Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase. Effects of exogenous amines on the slow formation of intermediates Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase. Effects of exogenous amines on the slow formation of intermediates Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase. Effects of exogenous amines on the slow formation of intermediates Journal of Biological Chemistry, 265, 22306-22312 Journal of Biological Chemistry, 265, 22306-22312 Journal of Biological Chemistry, 265, 22306-22312 1990/12/01 Disclose to all
Shiroh Futaki, Takashi Taike, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takashi Taike, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takashi Taike, Tadashi Akita, Kouki Kitagawa A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine Journal of the Chemical Society, Chemical Communications, 523-524 Journal of the Chemical Society, Chemical Communications, 523-524 Journal of the Chemical Society, Chemical Communications, 523-524 1990/12/01 Disclose to all
Shiroh Futaki, Takeshi Yagami, Takashi Taike, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takeshi Yagami, Takashi Taike, Tadashi Akita, Kouki Kitagawa Shiroh Futaki, Takeshi Yagami, Takashi Taike, Tadashi Akita, Kouki Kitagawa Sulphur trioxide/thiol: A novel system for the reduction of methionine sulphoxide Sulphur trioxide/thiol: A novel system for the reduction of methionine sulphoxide Sulphur trioxide/thiol: A novel system for the reduction of methionine sulphoxide Journal of the Chemical Society, Perkin Transactions 1, 653-658 Journal of the Chemical Society, Perkin Transactions 1, 653-658 Journal of the Chemical Society, Perkin Transactions 1, 653-658 1990/12/01 Disclose to all
S. Futaki; T. Taike; T. Akita; K. Kitagawa Shiroh Futaki, Takashi Taike, Tadashi Akita, Kouki Kitagawa S. Futaki; T. Taike; T. Akita; K. Kitagawa A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine A new approach for the synthesis of tyrosine sulphate containing peptides: Use of the p-(methylsulphinyl)benzyl group as a key protecting group of serine Journal of the Chemical Society, Chemical Communications, 7, 523-524 Journal of the Chemical Society, Chemical Communications, 7, 523-524 Journal of the Chemical Society, Chemical Communications, 7, 523-524 1990/12/01 Refereed English Disclose to all
K. Kitagawa; T. Tomoyasu; S. Futaki; T. Akita; S. Higashide; K. I noue; T. Tobe Kouki Kitagawa, Takahiro Tomoyasu, Shiroh Futaki, Tadashi Akita, Shunichi Higashide, Kazutomo Inoue, Takayoshi Tobe K. Kitagawa; T. Tomoyasu; S. Futaki; T. Akita; S. Higashide; K. I noue; T. Tobe Solution synthesis of human peptide YY (hPYY) Solution Synthesis of Human Peptide YY (hPYY) Solution synthesis of human peptide YY (hPYY) Chemical and Pharmaceutical Bulletin, 38, 6, 1731-1734 Chemical and Pharmaceutical Bulletin, 38, 6, 1731-1734 Chemical and Pharmaceutical Bulletin, 38, 6, 1731-1734 1990/01/01 Refereed English Disclose to all
S. Futaki; T. Yagami; T. Taike; T. Ogawa; T. Akita; K. Kitagawa Shiroh Futaki, Takeshi Yagami, Takashi Taike, Toyoko Ogawa, Tadashi Akita, Kouki Kitagawa S. Futaki; T. Yagami; T. Taike; T. Ogawa; T. Akita; K. Kitagawa Facile reduction of methionine sulfoxide with sulfur trioxide/iodide ion system Facile Reduction of Methionine Sulfoxide with Sulfur Trioxide/Iodide Ion System Facile reduction of methionine sulfoxide with sulfur trioxide/iodide ion system Chemical and Pharmaceutical Bulletin, 38, 5, 1165-1169 Chemical and Pharmaceutical Bulletin, 38, 5, 1165-1169 Chemical and Pharmaceutical Bulletin, 38, 5, 1165-1169 1990/01/01 Refereed English Disclose to all
H. Hirao; T. Fujita; Y. Iwasaki; H. Ide; S. Inoue; K. Kitagawa; S. Futaki; H. Kawanishi; T. Akita H. Hirao, T. Fujita, Y. Iwasaki, H. Ide, S. Inoue, K. Kitagawa, S. Futaki, H. Kawanishi, T. Akita H. Hirao; T. Fujita; Y. Iwasaki; H. Ide; S. Inoue; K. Kitagawa; S. Futaki; H. Kawanishi; T. Akita Studies on anti-allergic agent. I. 1,2,3-trisubstituted-2-propen-1-one derivatives, 3,4-disubstituted-4-oxo-2-butenoic acids and the related compounds Studies on anti-allergic agent. I. 1,2,3-trisubstituted-2-propen-1-one derivatives, 3,4-disubstituted-4-oxo-2-butenoic acids and the related compounds Studies on anti-allergic agent. I. 1,2,3-trisubstituted-2-propen-1-one derivatives, 3,4-disubstituted-4-oxo-2-butenoic acids and the related compounds Yakugaku Zasshi, 110, 10, 727-736 Yakugaku Zasshi, 110, 10, 727-736 Yakugaku Zasshi, 110, 10, 727-736 1990/01/01 Refereed English Disclose to all
K. Kitagawa; T. Kawamoto; S. Futaki; S. Kiyama; T. Akita; H. Moritoki; Y. Kiso Kouki Kitagawa, Tatsuhiko Kawamoto, Shiroh Futaki, Shinya Kiyama, Yoshiaki Kiso, Tadashi Akita, Hideki Moritoki K. Kitagawa; T. Kawamoto; S. Futaki; S. Kiyama; T. Akita; H. Moritoki; Y. Kiso Solution syntheses of two enkephalin-containing peptides, peptide E and dynorphin(1-24), using N(in)-(2,4,6-triisopropylphenylsulfonyl)tryptophan Solution Syntheses of Two Enkephalin-Containing Peptides, Peptide E and Dynorphin(l—24), Using N<sup>in</sup>-(2,4,6-Triisopropylphenylsulfonyl)tryptophan Solution syntheses of two enkephalin-containing peptides, peptide E and dynorphin(1-24), using N(in)-(2,4,6-triisopropylphenylsulfonyl)tryptophan Chemical and Pharmaceutical Bulletin, 37, 10, 2631-2638 Chemical and Pharmaceutical Bulletin, 37, 10, 2631-2638 Chemical and Pharmaceutical Bulletin, 37, 10, 2631-2638 1989/01/01 Refereed English Disclose to all
Nobutaka Fujii, Shiroh Futaki, Hiroshi Morimoto, Kazutomo Inoue, Ryuichiro Doi, Takayoshi Tobe, Haruaki Yajima Nobutaka Fujii, Shiroh Futaki, Hiroshi Morimoto, Kazutomo Inoue, Ryuichiro Doi, Takayoshi Tobe, Haruaki Yajima Nobutaka Fujii, Shiroh Futaki, Hiroshi Morimoto, Kazutomo Inoue, Ryuichiro Doi, Takayoshi Tobe, Haruaki Yajima Total synthesis of human cholecystokinin-33 Total synthesis of human cholecystokinin-33 Total synthesis of human cholecystokinin-33 Journal of the Chemical Society, Chemical Communications, 324-325 Journal of the Chemical Society, Chemical Communications, 324-325 Journal of the Chemical Society, Chemical Communications, 324-325 1988/01/01 Disclose to all
N. Fujii; S. Futaki; S. Funakoshi; K. Akaji; H. Morimoto; O. Ikemura; H. Yajima Nobutaka Fujii, Shiroh Futaki, Susumu Funakoshi, Kenichi Akaji, Hiroshi Morimoto, Osamu Ikemura, Haruaki Yajima N. Fujii; S. Futaki; S. Funakoshi; K. Akaji; H. Morimoto; O. Ikemura; H. Yajima Studies on peptides. CLIX. Preparation of a protected 33-residue peptide for the synthesis of human cholecystokinin (hCCK-33) Studies on Peptides. CLIX. Preparation of a Protected 33-Residue Peptide for the Synthesis of Human Cholecystokinin (hCCK-33) Studies on peptides. CLIX. Preparation of a protected 33-residue peptide for the synthesis of human cholecystokinin (hCCK-33) Chemical and Pharmaceutical Bulletin, 36, 9, 3271-3280 Chemical and Pharmaceutical Bulletin, 36, 9, 3271-3280 Chemical and Pharmaceutical Bulletin, 36, 9, 3271-3280 1988/01/01 Refereed English Disclose to all
N. Fujii; S. Futaki; H. Morimoto; K. Inoue; R. Doi; T. Tobe; H. Yajima Nobutaka Fujii, Shiroh Futaki, Hiroshi Morimoto, Kazutomo Inoue, Ryuichiro Doi, Takayoshi Tobe, Haruaki Yajima N. Fujii; S. Futaki; H. Morimoto; K. Inoue; R. Doi; T. Tobe; H. Yajima Total synthesis of human cholecystokinin-33 Total synthesis of human cholecystokinin-33 Total synthesis of human cholecystokinin-33 Journal of the Chemical Society - Series Chemical Communications, 4, 324-325 Journal of the Chemical Society, Chemical Communications, 4, 324-325 Journal of the Chemical Society - Series Chemical Communications, 4, 324-325 1988/01/01 Refereed English Disclose to all
Y. Iwasaki; T. Fujita; H. Yabe; H. Hirao; K. Kitagawa; S. Futaki; T. Inoue; T. Matsuzaki; T. Akita Y. Iwasaki, T. Fujita, H. Yabe, H. Hirao, K. Kitagawa, S. Futaki, T. Inoue, T. Matsuzaki, T. Akita Y. Iwasaki; T. Fujita; H. Yabe; H. Hirao; K. Kitagawa; S. Futaki; T. Inoue; T. Matsuzaki; T. Akita Synthesis and antifungal activity of a series of novel 2-propen-1-one Synthesis and antifungal activity of a series of novel 2-propen-1-one Synthesis and antifungal activity of a series of novel 2-propen-1-one Yakugaku Zasshi, 108, 10, 942-950 Yakugaku Zasshi, 108, 10, 942-950 Yakugaku Zasshi, 108, 10, 942-950 1988/01/01 Refereed English Disclose to all
F. A. Robey, K. Ohura, S. Futaki, N. Fujii, H. Yajima, N. Goldman, K. D. Jones, S. Wahl F. A. Robey, K. Ohura, S. Futaki, N. Fujii, H. Yajima, N. Goldman, K. D. Jones, S. Wahl F. A. Robey, K. Ohura, S. Futaki, N. Fujii, H. Yajima, N. Goldman, K. D. Jones, S. Wahl Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity Journal of Biological Chemistry, 262, 7053-7057 Journal of Biological Chemistry, 262, 7053-7057 Journal of Biological Chemistry, 262, 7053-7057 1987/09/16 Disclose to all
FUJII, N; NOMIZU, M; FUTAKI, S; OTAKA, A; FUNAKOSHI, S; AKAJI, K; WATANABE, K; YAJIMA, H Nobutaka Fujii, Motoyoshi Nomizu, Shiroh Futaki, Akira Otaka, Susumu Funakoshi, Kenichi Akaji, Kazuhide Watanabe, Haruaki Yajima FUJII, N; NOMIZU, M; FUTAKI, S; OTAKA, A; FUNAKOSHI, S; AKAJI, K; WATANABE, K; YAJIMA, H STUDIES ON PEPTIDES .132. EVALUATION OF 2 BETA-CARBOXYL PROTECTING GROUPS OF ASPARTIC-ACID, CYCLOHEPTYL AND CYCLOOCTYL, FOR PEPTIDE-SYNTHESIS Studies on Peptides. CXXXII. Evaluation of Two /1-Carboxyl Protecting Groups of Aspartic Acid, Cycloheptyl and Cyclooctyl, for Peptide Synthesis STUDIES ON PEPTIDES .132. EVALUATION OF 2 BETA-CARBOXYL PROTECTING GROUPS OF ASPARTIC-ACID, CYCLOHEPTYL AND CYCLOOCTYL, FOR PEPTIDE-SYNTHESIS CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 2, 864-868 Chemical and Pharmaceutical Bulletin, 34, 2, 864-868 CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 2, 864-868 1986/01/01 Refereed English Disclose to all
YAJIMA, H; FUTAKI, S; OTAKA, A; YAMASHITA, T; FUNAKOSHI, S; BESSHO, K; FUJII, N; AKAJI, K Haruaki Yajima, Shiroh Futaki, Akira Otaka, Takeyoshi Yamashita, Susumu Funakoshi, Kiyoshi Bessho, Nobutaka Fujii, Kenichi Akaji YAJIMA, H; FUTAKI, S; OTAKA, A; YAMASHITA, T; FUNAKOSHI, S; BESSHO, K; FUJII, N; AKAJI, K STUDIES ON PEPTIDES .143. EVALUATION OF BETA-MENTHYLASPARTATE FOR PEPTIDE-SYNTHESIS Studies on Peptides. CXLIII. Evaluation of β-Menthylaspartate for Peptide Synthesis STUDIES ON PEPTIDES .143. EVALUATION OF BETA-MENTHYLASPARTATE FOR PEPTIDE-SYNTHESIS CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 10, 4356-4361 Chemical and Pharmaceutical Bulletin, 34, 10, 4356-4361 CHEMICAL & PHARMACEUTICAL BULLETIN, 34, 10, 4356-4361 1986/01/01 Refereed English Disclose to all
H. Yajima; S. Futaki; N. Fujii; K. Akaji; S. Funakoshi; M. Sakurai; S. Katakura; K. Inoue; R. Hosotani; T. Tobe Haruaki Yajima, Shiroh Futaki, Nobutaka Fujii, Kenichi Akaji, Susumu Funakoshi, Mitsuya Sakurai, Shinichi Katakura, Kazutomo Inoue, Ryo Hosotani, Takayoshi Tobe, Tomio Segawa, Atsuko Inoue, Kazuhiko Tatemoto, Viktor Mutt H. Yajima; S. Futaki; N. Fujii; K. Akaji; S. Funakoshi; M. Sakurai; S. Katakura; K. Inoue; R. Hosotani; T. Tobe Studies on peptides. CXXXIII. Synthesis and biological activity of galanin, a novel porcine intestinal polypeptide Studies on Peptides. CXXXIII. Synthesis and Biological Activity of Galanin, a Novel Porcine Intestinal Polypeptide Studies on peptides. CXXXIII. Synthesis and biological activity of galanin, a novel porcine intestinal polypeptide Chemical and Pharmaceutical Bulletin, 34, 2, 528-539 Chemical and Pharmaceutical Bulletin, 34, 2, 528-539 Chemical and Pharmaceutical Bulletin, 34, 2, 528-539 1986/01/01 Refereed English Disclose to all
N. Fujii; S. Futaki; K. Akaji Nobutaka Fujii, Shiroh Futaki, Kenichi Akaji, Haruaki Yajima, Atsuko Inoue, Tomio Segawa N. Fujii; S. Futaki; K. Akaji Studies on peptides. CXXIX. Application of N(in)-mesitylenesulfonyl-tryptophan for the syntheses of neuromedin B and neuromedin C Studies on Peptides. CXXIX. Application of N<sup>in</sup>-Mesitylenesulfony1tryptophan for the Syntheses of Neuromedin B and Neuromedin C Studies on peptides. CXXIX. Application of N(in)-mesitylenesulfonyl-tryptophan for the syntheses of neuromedin B and neuromedin C Chemical and Pharmaceutical Bulletin, 33, 9, 3731-3737 Chemical and Pharmaceutical Bulletin, 33, 9, 3731-3737 Chemical and Pharmaceutical Bulletin, 33, 9, 3731-3737 1985/01/01 Refereed English Disclose to all
N. Fujii; S. Futaki; K. Yasumura; H. Yajima Nobutaka Fujii, Shiroh Futaki, Koichi Yasumura, Haruaki Yajima N. Fujii; S. Futaki; K. Yasumura; H. Yajima Studies on peptides. CXXI. Nin-mesitylenesulfonyl-tryptophan, a new derivative for peptide synthesis. Studies on Peptides. CXXI.<sup>1,2)</sup> N<sup>in</sup>-Mesitylenesulfonyl-tryptophan, a New Derivative for Peptide Synthesis Studies on peptides. CXXI. Nin-mesitylenesulfonyl-tryptophan, a new derivative for peptide synthesis. Chemical and Pharmaceutical Bulletin, 32, 7, 2660-2665 Chemical and Pharmaceutical Bulletin, 32, 7, 2660-2665 Chemical and Pharmaceutical Bulletin, 32, 7, 2660-2665 1984/01/01 Refereed English Disclose to all
N. Fujii; Y. Hayashi; S. Futaki; K. Akaji; H. Yajima; T. Kitagawa Nobutaka Fujii, Yoshio Hayashi, Shiroh Futaki, Kenichi Akaji, Haruaki Yajima, Tsunehiro Kitagawa N. Fujii; Y. Hayashi; S. Futaki; K. Akaji; H. Yajima; T. Kitagawa Studies on peptides. CXXII. N-Succinimidyl-p-(2-nitrovinyl)-benzoate and its m-isomer, as heterobifunctional conjugating reagents for immunoassay. Studies on Peptides. CXXII.<sup>1,2)</sup> N-Succinimidyl-p-(2-nitrovinyl)-benzoate and Its m-Isomer, as Heterobifunctional Conjugating Reagents for Immunoassay Studies on peptides. CXXII. N-Succinimidyl-p-(2-nitrovinyl)-benzoate and its m-isomer, as heterobifunctional conjugating reagents for immunoassay. Chemical and Pharmaceutical Bulletin, 32, 12, 5036-5039 Chemical and Pharmaceutical Bulletin, 32, 12, 5036-5039 Chemical and Pharmaceutical Bulletin, 32, 12, 5036-5039 1984/01/01 Refereed English Disclose to all
S. Sasaki; S. Futaki S. Sasaki; S. Futaki Life-oriented chemistry in pharmaceutical sciences -Chemistry challenge to mystery of life- Life-oriented chemistry in pharmaceutical sciences -Chemistry challenge to mystery of life- Yakugaku Zasshi, 134, 4, 499-500 , 134, 4, 499-500 Yakugaku Zasshi, 134, 4, 499-500 2014/04 Refereed English Disclose to all
Hirose, H.; Takeuchi, T.; Nakase, I.; Futaki, S. Hirose, H.; Takeuchi, T.; Nakase, I.; Futaki, S. The formation of particle-like structure on cell membranes accompanies direct influx of arginine-rich peptides into cells The formation of particle-like structure on cell membranes accompanies direct influx of arginine-rich peptides into cells BIOPOLYMERS, 96, 4, 498-498 , 96, 4, 498-498 BIOPOLYMERS, 96, 4, 498-498 2011 Refereed English Disclose to all
S. Yanaka; M. Kudou; Y. Tanaka; T. Sasaki; S. Takemoto; A. Sakata; Y. Hattori; T. Koshi; S. Futaki; K. Tsumoto; T. Nakashima S. Yanaka; M. Kudou; Y. Tanaka; T. Sasaki; S. Takemoto; A. Sakata; Y. Hattori; T. Koshi; S. Futaki; K. Tsumoto; T. Nakashima Contribution of the flexible loop region to the function of staphylococcal enterotoxin B Contribution of the flexible loop region to the function of staphylococcal enterotoxin B Protein Engineering, Design and Selection, 23, 5, 415-421 , 23, 5, 415-421 Protein Engineering, Design and Selection, 23, 5, 415-421 2010/05 Refereed English Disclose to all
KAWAMOTO, Shuhei.; TALASU, Masako,; MIYAKAWA, Takeshi.; MORIKAWA, Ryota.; ODA, Tatsuki.; FUTAKI, Shiroh.; NOGAO, Hidemi. KAWAMOTO, Shuhei.; TALASU, Masako,; MIYAKAWA, Takeshi.; MORIKAWA, Ryota.; ODA, Tatsuki.; FUTAKI, Shiroh.; NOGAO, Hidemi. Binding of Tat peptides on DOPC and DOPG lipid bilayer membrane studied by molecular dynamics simulations Binding of Tat peptides on DOPC and DOPG lipid bilayer membrane studied by molecular dynamics simulations Molecular Simulation, DOI:10.1080/08927022.2010.536546, Molecular Simulation, DOI:10.1080/08927022.2010.536546, 2010 Refereed English Disclose to all
Y. Sakurai; H. Hatakeyama; H. Akita; M. Oishi; Y. Nagasaki; S. Futaki; H. Harashima Y. Sakurai; H. Hatakeyama; H. Akita; M. Oishi; Y. Nagasaki; S. Futaki; H. Harashima Efficient short interference rna delivery to tumor cells using a combination of octaarginine, gala and tumor-specific, cleavable polyethylene glycol system Efficient short interference rna delivery to tumor cells using a combination of octaarginine, gala and tumor-specific, cleavable polyethylene glycol system Biological and Pharmaceutical Bulletin, 32, 5, 928-932 , 32, 5, 928-932 Biological and Pharmaceutical Bulletin, 32, 5, 928-932 2009/05 Refereed English Disclose to all
S. Futaki; I. Nakase; A. Tadokoro; T. Takeuchi; A.T. Jones S. Futaki; I. Nakase; A. Tadokoro; T. Takeuchi; A.T. Jones Arginine-rich peptides and their internalization mechanisms Arginine-rich peptides and their internalization mechanisms Biochemical Society Transactions, 35, 784-787 , 35, 784-787 Biochemical Society Transactions, 35, 784-787 2007/08 Refereed English Disclose to all
I.A. Khalil; K. Kogure; S. Futaki; S. Hama; H. Akita; M. Ueno; H. Kishida; M. Kudoh; Y. Mishina; K. Kataoka; M. Yamada; H. Harashima I.A. Khalil; K. Kogure; S. Futaki; S. Hama; H. Akita; M. Ueno; H. Kishida; M. Kudoh; Y. Mishina; K. Kataoka; M. Yamada; H. Harashima Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery Gene Therapy, 14, 8, 682-689 , 14, 8, 682-689 Gene Therapy, 14, 8, 682-689 2007/04 Refereed English Disclose to all
H. Noguchi; Y. Nakai; M. Ueda; Y. Masui; S. Futaki; N. Kobayashi; S. Hayashi; S. Matsumoto H. Noguchi; Y. Nakai; M. Ueda; Y. Masui; S. Futaki; N. Kobayashi; S. Hayashi; S. Matsumoto Activation of c-Jun NH<sub>2</sub>-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor Activation of c-Jun NH<sub>2</sub>-terminal kinase (JNK) pathway during islet transplantation and prevention of islet graft loss by intraportal injection of JNK inhibitor Diabetologia, 50, 3, 612-619 , 50, 3, 612-619 Diabetologia, 50, 3, 612-619 2007/03 Refereed English Disclose to all
S. Kameyama; M. Horie; T. Kikuchi; T. Omura; T. Takeuchi; I. Nakase; Y. Sugiura; S. Futaki S. Kameyama; M. Horie; T. Kikuchi; T. Omura; T. Takeuchi; I. Nakase; Y. Sugiura; S. Futaki Effects of cell-permeating peptide binding on the distribution of <sup>125</sup>I-labeled Fab fragment in rats Effects of cell-permeating peptide binding on the distribution of <sup>125</sup>I-labeled Fab fragment in rats Bioconjugate Chemistry, 17, 3, 597-602 , 17, 3, 597-602 Bioconjugate Chemistry, 17, 3, 597-602 2006/05/17 Refereed English Disclose to all
二木史朗 二木史朗 ペプチドによる細胞内移送制御 ペプチドによる細胞内移送制御 高分子, 55, 5 , 55, 5 高分子, 55, 5 2006/05/01 Refereed English Disclose to all
I.A. Khalil; K. Kogure; S. Futaki; H. Harashima I.A. Khalil; K. Kogure; S. Futaki; H. Harashima High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression Journal of Biological Chemistry, 281, 6, 3544-3551 , 281, 6, 3544-3551 Journal of Biological Chemistry, 281, 6, 3544-3551 2006/02/10 Refereed English Disclose to all
S. Al-Taei; N.A. Penning; J.C. Simpson; S. Futaki; T. Takeuchi; I. Nakase; A.T. Jones S. Al-Taei; N.A. Penning; J.C. Simpson; S. Futaki; T. Takeuchi; I. Nakase; A.T. Jones Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors Bioconjugate Chemistry, 17, 1, 90-100 , 17, 1, 90-100 Bioconjugate Chemistry, 17, 1, 90-100 2006/01 Refereed English Disclose to all
S. Futaki S. Futaki Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms Biopolymers - Peptide Science Section, 84, 3, 241-249 , 84, 3, 241-249 Biopolymers - Peptide Science Section, 84, 3, 241-249 2006 Refereed English Disclose to all
T. Takeuchi; M. Kosuge; A. Tadokoro; Y. Sugiura; M. Nishi; M. Kawata; N. Sakai; S. Matile; S. Futaki T. Takeuchi; M. Kosuge; A. Tadokoro; Y. Sugiura; M. Nishi; M. Kawata; N. Sakai; S. Matile; S. Futaki Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate. Direct and rapid cytosolic delivery using cell-penetrating peptides mediated by pyrenebutyrate. ACS chemical biology, 1, 5, 299-303 , 1, 5, 299-303 ACS chemical biology, 1, 5, 299-303 2006 Refereed English Disclose to all
H. Akita; M. Tanimoto; T. Masuda; K. Kogure; S. Hama; K. Ninomiya; S. Futaki; H. Harashima H. Akita; M. Tanimoto; T. Masuda; K. Kogure; S. Hama; K. Ninomiya; S. Futaki; H. Harashima Evaluation of the nuclear delivery and intra-nuclear transcription of plasmid DNA condensed with μ (mu) and NLS-μ by cytoplasmic and nuclear microinjection: A comparative study with poly-L-lysine Evaluation of the nuclear delivery and intra-nuclear transcription of plasmid DNA condensed with μ (mu) and NLS-μ by cytoplasmic and nuclear microinjection: A comparative study with poly-L-lysine Journal of Gene Medicine, 8, 2, 198-206 , 8, 2, 198-206 Journal of Gene Medicine, 8, 2, 198-206 2006 Refereed English Disclose to all
Y. Nakamura; K. Kogure; Y. Yamada; S. Futaki; H. Harashima Y. Nakamura; K. Kogure; Y. Yamada; S. Futaki; H. Harashima Significant and prolonged antisense effect of a multifunctional envelope-type nano device encapsulating antisense oligodeoxynucleotide Significant and prolonged antisense effect of a multifunctional envelope-type nano device encapsulating antisense oligodeoxynucleotide Journal of Pharmacy and Pharmacology, 58, 4, 431-437 , 58, 4, 431-437 Journal of Pharmacy and Pharmacology, 58, 4, 431-437 2006 Refereed English Disclose to all
S. Futaki; Y. Masui; I. Nakase; Y. Sugiura; T. Nakamura; K. Kogure; H. Harashima S. Futaki; Y. Masui; I. Nakase; Y. Sugiura; T. Nakamura; K. Kogure; H. Harashima Unique features of a pH-sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes Unique features of a pH-sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes Journal of Gene Medicine, 7, 11, 1450-1458 , 7, 11, 1450-1458 Journal of Gene Medicine, 7, 11, 1450-1458 2005/11 Refereed English Disclose to all
Y. Yamada; Y. Shinohara; T. Kakudo; S. Chaki; S. Futaki; H. Kamiya; H. Harashima Y. Yamada; Y. Shinohara; T. Kakudo; S. Chaki; S. Futaki; H. Kamiya; H. Harashima Mitochondrial delivery of mastoparan with transferrin liposomes equipped with a pH-sensitive fusogenic peptide for selective cancer therapy Mitochondrial delivery of mastoparan with transferrin liposomes equipped with a pH-sensitive fusogenic peptide for selective cancer therapy International Journal of Pharmaceutics, 303, 1-2, 1-7 , 303, 1-2, 1-7 International Journal of Pharmaceutics, 303, 1-2, 1-7 2005/10/13 Refereed English Disclose to all
R. Moriguchi; K. Kogure; H. Akita; S. Futaki; M. Miyagishi; K. Taira; H. Harashima R. Moriguchi; K. Kogure; H. Akita; S. Futaki; M. Miyagishi; K. Taira; H. Harashima A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids International Journal of Pharmaceutics, 301, 1-2, 277-285 , 301, 1-2, 277-285 International Journal of Pharmaceutics, 301, 1-2, 277-285 2005/09/14 Refereed English Disclose to all
H. Noguchi; Y. Nakai; S. Matsumoto; M. Kawaguchi; M. Ueda; T. Okitsu; Y. Iwanaga; Y. Yonekawa; H. Nagata; K. Minami; Y. Masui; S. Futaki; K. Tanaka H. Noguchi; Y. Nakai; S. Matsumoto; M. Kawaguchi; M. Ueda; T. Okitsu; Y. Iwanaga; Y. Yonekawa; H. Nagata; K. Minami; Y. Masui; S. Futaki; K. Tanaka Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function American Journal of Transplantation, 5, 8, 1848-1855 , 5, 8, 1848-1855 American Journal of Transplantation, 5, 8, 1848-1855 2005/08 Refereed English Disclose to all
E. Okamura; K. Ninomiya; S. Futaki; Y. Nagai; T. Kimura; C. Wakai; N. Matubayasi; Y. Sugiura; M. Nakahara E. Okamura; K. Ninomiya; S. Futaki; Y. Nagai; T. Kimura; C. Wakai; N. Matubayasi; Y. Sugiura; M. Nakahara Real-time in-cell <sup>19</sup>F NMR study on uptake of fluorescent and nonfluorescent <sup>19</sup>F-octaarginines into human Jurkat cells Real-time in-cell <sup>19</sup>F NMR study on uptake of fluorescent and nonfluorescent <sup>19</sup>F-octaarginines into human Jurkat cells Chemistry Letters, 34, 7, 1064-1065 , 34, 7, 1064-1065 Chemistry Letters, 34, 7, 1064-1065 2005/07/05 Refereed English Disclose to all
T. Nakatsukasa; Y. Shiraishi; S. Negi; M. Imanishi; S. Futaki; Y. Sugiura T. Nakatsukasa; Y. Shiraishi; S. Negi; M. Imanishi; S. Futaki; Y. Sugiura Site-specific DNA cleavage by artificial zinc finger-type nuclease with cerium-binding peptide Site-specific DNA cleavage by artificial zinc finger-type nuclease with cerium-binding peptide Biochemical and Biophysical Research Communications, 330, 1, 247-252 , 330, 1, 247-252 Biochemical and Biophysical Research Communications, 330, 1, 247-252 2005/04/29 Refereed English Disclose to all
S. Futaki; I. Nakase; T. Suzuki; D. Nameki; E.-I. Kodama; M. Matsuoka; Y. Sugiura S. Futaki; I. Nakase; T. Suzuki; D. Nameki; E.-I. Kodama; M. Matsuoka; Y. Sugiura RNase S complex bearing arginine-rich peptide and anti-HIV activity RNase S complex bearing arginine-rich peptide and anti-HIV activity Journal of Molecular Recognition, 18, 2, 169-174 , 18, 2, 169-174 Journal of Molecular Recognition, 18, 2, 169-174 2005/03 Refereed English Disclose to all
F. Perret; M. Nishihara; T. Takeuchi; S. Futaki; A.N. Lazar; A.W. Coleman; N. Sakai; S. Matile F. Perret; M. Nishihara; T. Takeuchi; S. Futaki; A.N. Lazar; A.W. Coleman; N. Sakai; S. Matile Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells Journal of the American Chemical Society, 127, 4, 1114-1115 , 127, 4, 1114-1115 Journal of the American Chemical Society, 127, 4, 1114-1115 2005/02/02 Refereed English Disclose to all
N. Sakai; T. Takeuchi; S. Futaki; S. Matile N. Sakai; T. Takeuchi; S. Futaki; S. Matile Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes Direct observation of anion-mediated translocation of fluorescent oligoarginine carriers into and across bulk liquid and anionic bilayer membranes ChemBioChem, 6, 1, 114-122 , 6, 1, 114-122 ChemBioChem, 6, 1, 114-122 2005/01 Refereed English Disclose to all
D. Mudhakir; H. Akita; I.A. Khalil; S. Futaki; H. Harashima D. Mudhakir; H. Akita; I.A. Khalil; S. Futaki; H. Harashima Pharmacokinetic analysis of the tissue distribution of octaarginine modified liposomes in mice. Pharmacokinetic analysis of the tissue distribution of octaarginine modified liposomes in mice. Drug metabolism and pharmacokinetics., 20, 4, 275-281 , 20, 4, 275-281 Drug metabolism and pharmacokinetics., 20, 4, 275-281 2005 Refereed English Disclose to all
S. Futaki S. Futaki Membrane-permeable arginine-rich peptides and the translocation mechanisms Membrane-permeable arginine-rich peptides and the translocation mechanisms Advanced Drug Delivery Reviews, 57, 4 SPEC.ISS., 547-558 , 57, 4 SPEC.ISS., 547-558 Advanced Drug Delivery Reviews, 57, 4 SPEC.ISS., 547-558 2005 Refereed English Disclose to all
H. Noguchi; S. Matsumoto; T. Okitsu; Y. Iwanaga; Y. Yonekawa; H. Nagata; M. Matsushita; F.-Y. Wei; H. Matsui; K. Minami; S. Seino; Y. Masui; S. Futaki; K. Tanaka H. Noguchi; S. Matsumoto; T. Okitsu; Y. Iwanaga; Y. Yonekawa; H. Nagata; M. Matsushita; F.-Y. Wei; H. Matsui; K. Minami; S. Seino; Y. Masui; S. Futaki; K. Tanaka PDX-1 protein is internalized by lipid raft-dependent macropinocytosis PDX-1 protein is internalized by lipid raft-dependent macropinocytosis Cell Transplantation, 14, 9, 637-645 , 14, 9, 637-645 Cell Transplantation, 14, 9, 637-645 2005 Refereed English Disclose to all
M. Nishihara; F. Perret; T. Takeuchi; S. Futaki; A.N. Lazar; A.W. Coleman; N. Sakai; S. Matile M. Nishihara; F. Perret; T. Takeuchi; S. Futaki; A.N. Lazar; A.W. Coleman; N. Sakai; S. Matile Arginine magic with new counterions up the sleeve Arginine magic with new counterions up the sleeve Organic and Biomolecular Chemistry, 3, 9, 1659-1669 , 3, 9, 1659-1669 Organic and Biomolecular Chemistry, 3, 9, 1659-1669 2005 Refereed English Disclose to all
S. Futaki; T. Kiwada; Y. Sugiura S. Futaki; T. Kiwada; Y. Sugiura Control of peptide structure and recognition by Fe(III)-induced helix destabilization Control of peptide structure and recognition by Fe(III)-induced helix destabilization Journal of the American Chemical Society, 126, 48, 15762-15769 , 126, 48, 15762-15769 Journal of the American Chemical Society, 126, 48, 15762-15769 2004/12/08 Refereed English Disclose to all
I. Nakase; M. Niwa; T. Takeuchi; K. Sonomura; N. Kawabata; Y. Koike; M. Takehashi; S. Tanaka; K. Ueda; J.C. Simpson; A.T. Jones; Y. Sugiura; S. Futaki I. Nakase; M. Niwa; T. Takeuchi; K. Sonomura; N. Kawabata; Y. Koike; M. Takehashi; S. Tanaka; K. Ueda; J.C. Simpson; A.T. Jones; Y. Sugiura; S. Futaki Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement Cellular uptake of arginine-rich peptides: Roles for macropinocytosis and actin rearrangement Molecular Therapy, 10, 6, 1011-1022 , 10, 6, 1011-1022 Molecular Therapy, 10, 6, 1011-1022 2004/12 Refereed English Disclose to all
K. Kogure; R. Moriguchi; K. Sasaki; M. Ueno; S. Futaki; H. Harashima K. Kogure; R. Moriguchi; K. Sasaki; M. Ueno; S. Futaki; H. Harashima Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method Journal of Controlled Release, 98, 2, 317-323 , 98, 2, 317-323 Journal of Controlled Release, 98, 2, 317-323 2004/08/11 Refereed English Disclose to all
T. Kakudo; S. Chaki; S. Futaki; I. Nakase; K. Akaji; T. Kawakami; K. Maruyama; H. Kamiya; H. Harashima T. Kakudo; S. Chaki; S. Futaki; I. Nakase; K. Akaji; T. Kawakami; K. Maruyama; H. Kamiya; H. Harashima Transferrin-Modified Liposomes Equipped with a pH-Sensitive Fusogenic Peptide: An Artificial Viral-like Delivery System Transferrin-Modified Liposomes Equipped with a pH-Sensitive Fusogenic Peptide: An Artificial Viral-like Delivery System Biochemistry, 43, 19, 5618-5628 , 43, 19, 5618-5628 Biochemistry, 43, 19, 5618-5628 2004/05/18 Refereed English Disclose to all
S. Futaki; M. Niwa; I. Nakase; A. Tadokoro; Y. Zhang; M. Nagaoka; N. Wakako; Y. Sugiura S. Futaki; M. Niwa; I. Nakase; A. Tadokoro; Y. Zhang; M. Nagaoka; N. Wakako; Y. Sugiura Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins Bioconjugate Chemistry, 15, 3, 475-481 , 15, 3, 475-481 Bioconjugate Chemistry, 15, 3, 475-481 2004/05 Refereed English Disclose to all
I.A. Khalil; S. Futaki; M. Niwa; Y. Baba; N. Kaji; H. Kamiya; H. Harashima I.A. Khalil; S. Futaki; M. Niwa; Y. Baba; N. Kaji; H. Kamiya; H. Harashima Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation Gene Therapy, 11, 7, 636-644 , 11, 7, 636-644 Gene Therapy, 11, 7, 636-644 2004/04 Refereed English Disclose to all
S. Futaki; Y. Zhang; T. Kiwada; I. Nakase; T. Yagami; S. Oiki; Y. Sugiura S. Futaki; Y. Zhang; T. Kiwada; I. Nakase; T. Yagami; S. Oiki; Y. Sugiura Gramicidin-based channel systems for the detection of protein-ligand interaction Gramicidin-based channel systems for the detection of protein-ligand interaction Bioorganic and Medicinal Chemistry, 12, 6, 1343-1350 , 12, 6, 1343-1350 Bioorganic and Medicinal Chemistry, 12, 6, 1343-1350 2004/03/15 Refereed English Disclose to all
H. Akita; R. Ito; I.A. Khalil; S. Futaki; H. Harashima H. Akita; R. Ito; I.A. Khalil; S. Futaki; H. Harashima Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy Molecular Therapy, 9, 3, 443-451 , 9, 3, 443-451 Molecular Therapy, 9, 3, 443-451 2004/03 Refereed English Disclose to all
K. Kitagawa; H. Adachi; Y. Sekigawa; T. Yagami; S. Futaki; Y.J. Gu; K. Inoue K. Kitagawa; H. Adachi; Y. Sekigawa; T. Yagami; S. Futaki; Y.J. Gu; K. Inoue Total chemical synthesis of large CCK isoforms using a thioester segment condensation approach Total chemical synthesis of large CCK isoforms using a thioester segment condensation approach Tetrahedron, 60, 4, 907-918 , 60, 4, 907-918 Tetrahedron, 60, 4, 907-918 2004/01/19 Refereed English Disclose to all
S. Futaki; K. Tatsuto; Y. Shiraishi; Y. Sugiura S. Futaki; K. Tatsuto; Y. Shiraishi; Y. Sugiura Total Synthesis of Artificial Zinc-Finger Proteins: Problems and Perspectives Total Synthesis of Artificial Zinc-Finger Proteins: Problems and Perspectives Biopolymers - Peptide Science Section, 76, 2, 98-109 , 76, 2, 98-109 Biopolymers - Peptide Science Section, 76, 2, 98-109 2004 Refereed English Disclose to all
T. Ohwada; D. Kojima; T. Kiwada; S. Futaki; Y. Sugiura; K. Yamaguchi; Y. Nishi; Y. Kobayashi T. Ohwada; D. Kojima; T. Kiwada; S. Futaki; Y. Sugiura; K. Yamaguchi; Y. Nishi; Y. Kobayashi α,α-Disubstituted Glycines Bearing a Large Hydrocarbon Ring: Peptide Self-Assembly through Hydrophobic Recognition α,α-Disubstituted Glycines Bearing a Large Hydrocarbon Ring: Peptide Self-Assembly through Hydrophobic Recognition Chemistry - A European Journal, 10, 3, 617-626 , 10, 3, 617-626 Chemistry - A European Journal, 10, 3, 617-626 2004 Refereed English Disclose to all
Futaki S Futaki S Intracellular Delivery Using Arginine Peptides (Review) Intracellular Delivery Using Arginine Peptides (Review) J. Phar. Sci. Tech., Jpn, 64, 164-167 J. Phar. Sci. Tech., Jpn, 64, 164-167 2004 English Disclose to all
Futaki S Futaki S Peptide-mediated Drug Delivery (Review) Peptide-mediated Drug Delivery (Review) The Cell, 36, 428-431 The Cell, 36, 428-431 2004 English Disclose to all
Futaki S Futaki S Intracellular Delivery of Proteins and Macromolecules Using Carrier Peptides Intracellular Delivery of Proteins and Macromolecules Using Carrier Peptides Chemistry Today, Aug, 32-36 Chemistry Today, Aug, 32-36 2004 English Disclose to all
Nakase I, Futaki S Nakase I, Futaki S Intracellular Delivery of Proteins and Drugs Using Arginine Peptides Intracellular Delivery of Proteins and Drugs Using Arginine Peptides Chemistry, Nov, 68-69 Chemistry, Nov, 68-69 2004 English Disclose to all
A. Shibata; S. Murata; S. Ueno; S. Liu; S. Futaki; Y. Baba A. Shibata; S. Murata; S. Ueno; S. Liu; S. Futaki; Y. Baba Synthetic copoly(Lys/Phe) and poly(Lys) translocate through lipid bilayer membranes Synthetic copoly(Lys/Phe) and poly(Lys) translocate through lipid bilayer membranes Biochimica et Biophysica Acta - Biomembranes, 1616, 2, 147-155 , 1616, 2, 147-155 Biochimica et Biophysica Acta - Biomembranes, 1616, 2, 147-155 2003/10/13 Refereed English Disclose to all
S. Futaki; S. Goto; T. Suzuki; I. Nakase; Y. Sugiura S. Futaki; S. Goto; T. Suzuki; I. Nakase; Y. Sugiura Structural variety of membrane permeable peptides Structural variety of membrane permeable peptides Current Protein and Peptide Science, 4, 2, 87-96 , 4, 2, 87-96 Current Protein and Peptide Science, 4, 2, 87-96 2003/04 Refereed English Disclose to all
T. Nagasaki; T. Myohoji; T. Tachibana; S. Futaki; S. Tamagaki T. Nagasaki; T. Myohoji; T. Tachibana; S. Futaki; S. Tamagaki Can nuclear localization signals enhance nuclear localization of plasmid DNA? Can nuclear localization signals enhance nuclear localization of plasmid DNA? Bioconjugate Chemistry, 14, 2, 282-286 , 14, 2, 282-286 Bioconjugate Chemistry, 14, 2, 282-286 2003/03 Refereed English Disclose to all
R. Tachibana; S. Futaki; H. Harashima; H. Kiwada R. Tachibana; S. Futaki; H. Harashima; H. Kiwada pH-Sensitive Liposomes in Nuclear Targeting of Macromolecules pH-Sensitive Liposomes in Nuclear Targeting of Macromolecules Methods in Enzymology, 372, 349-361 , 372, 349-361 Methods in Enzymology, 372, 349-361 2003 Refereed English Disclose to all
S. Futaki; S. Goto; Y. Sugiura S. Futaki; S. Goto; Y. Sugiura Membrane permeability commonly shared among arginine-rich peptides Membrane permeability commonly shared among arginine-rich peptides Journal of Molecular Recognition, 16, 5, 260-264 , 16, 5, 260-264 Journal of Molecular Recognition, 16, 5, 260-264 2003 Refereed English Disclose to all
S. Futaki S. Futaki Preface Preface Current Protein and Peptide Science, 4, 2, xxx , 4, 2, xxx Current Protein and Peptide Science, 4, 2, xxx 2003 Refereed English Disclose to all
S. Futaki S. Futaki Arginine-rich peptides: Potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms Arginine-rich peptides: Potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms International Journal of Pharmaceutics, 245, 1-2, 1-7 , 245, 1-2, 1-7 International Journal of Pharmaceutics, 245, 1-2, 1-7 2002/10/01 Refereed English Disclose to all
Y. Zhang; S. Futaki; T. Kiwada; Y. Sugiura Y. Zhang; S. Futaki; T. Kiwada; Y. Sugiura Detection of protein-ligand interaction on the membranes using C-terminus biotin-tagged alamethicin Detection of protein-ligand interaction on the membranes using C-terminus biotin-tagged alamethicin Bioorganic and Medicinal Chemistry, 10, 8, 2635-2639 , 10, 8, 2635-2639 Bioorganic and Medicinal Chemistry, 10, 8, 2635-2639 2002/08 Refereed English Disclose to all
S. Tanaka; M. Takehashi; N. Matoh; S. Iida; T. Suzuki; S. Futaki; H. Hamada; E. Masliah; Y. Sugiura; K. Ueda S. Tanaka; M. Takehashi; N. Matoh; S. Iida; T. Suzuki; S. Futaki; H. Hamada; E. Masliah; Y. Sugiura; K. Ueda Generation of reactive oxygen species and activation of NF-κb by non-Aβ component of Alzheimer\\'s disease amyloid Generation of reactive oxygen species and activation of NF-κb by non-Aβ component of Alzheimer\\'s disease amyloid Journal of Neurochemistry, 82, 2, 305-315 , 82, 2, 305-315 Journal of Neurochemistry, 82, 2, 305-315 2002/07 Refereed English Disclose to all
S. Futaki; I. Nakase; T. Suzuki; Z. Youjun; Y. Sugiura S. Futaki; I. Nakase; T. Suzuki; Z. Youjun; Y. Sugiura Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides Biochemistry, 41, 25, 7925-7930 , 41, 25, 7925-7930 Biochemistry, 41, 25, 7925-7930 2002/06/25 Refereed English Disclose to all
Y. Okumura; Y. Kamikubo; S.A. Curriden; J. Wang; T. Kiwada; S. Futaki; K. Kitagawa; D.J. Loskutoff Y. Okumura; Y. Kamikubo; S.A. Curriden; J. Wang; T. Kiwada; S. Futaki; K. Kitagawa; D.J. Loskutoff Kinetic analysis of the interaction between vitronectin and the urokinase receptor Kinetic analysis of the interaction between vitronectin and the urokinase receptor Journal of Biological Chemistry, 277, 11, 9395-9404 , 277, 11, 9395-9404 Journal of Biological Chemistry, 277, 11, 9395-9404 2002/03/15 Refereed English Disclose to all
Y. Yano; T. Takemoto; S. Kobayashi; H. Yasui; H. Sakurai; W. Ohashi; M. Niwa; S. Futaki; Y. Sugiura; K. Matsuzaki Y. Yano; T. Takemoto; S. Kobayashi; H. Yasui; H. Sakurai; W. Ohashi; M. Niwa; S. Futaki; Y. Sugiura; K. Matsuzaki Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers Biochemistry, 41, 9, 3073-3080 , 41, 9, 3073-3080 Biochemistry, 41, 9, 3073-3080 2002/03/05 Refereed English Disclose to all
T. Suzuki; S. Futaki; M. Niwa; S. Tanaka; K. Ueda; Y. Sugiura T. Suzuki; S. Futaki; M. Niwa; S. Tanaka; K. Ueda; Y. Sugiura Possible existence of common internalization mechanisms among arginine-rich peptides Possible existence of common internalization mechanisms among arginine-rich peptides Journal of Biological Chemistry, 277, 4, 2437-2443 , 277, 4, 2437-2443 Journal of Biological Chemistry, 277, 4, 2437-2443 2002/01/25 Refereed English Disclose to all
S. Futaki S. Futaki Membrane permeable basic peptides: the potential of these peptides for the intracellular delivery of proteins and drugs Membrane permeable basic peptides: the potential of these peptides for the intracellular delivery of proteins and drugs Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 47, 11, 1415-1419 , 47, 11, 1415-1419 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 47, 11, 1415-1419 2002 Refereed English Disclose to all
Tamiya E, Futaki S, Yoshida K Tamiya E, Futaki S, Yoshida K Future of combinatorial Bioengineering Future of combinatorial Bioengineering Chemistry Today, 372, 23-30 Chemistry Today, 372, 23-30 2002 Refereed English Disclose to all
S. Futaki; M. Fukuda; M. Omote; K. Yamauchi; T. Yagami; M. Niwa; Y. Sugiura S. Futaki; M. Fukuda; M. Omote; K. Yamauchi; T. Yagami; M. Niwa; Y. Sugiura Alamethicin-leucine zipper hybrid peptide: A prototype for the design of artificial receptors and ion channels Alamethicin-leucine zipper hybrid peptide: A prototype for the design of artificial receptors and ion channels Journal of the American Chemical Society, 123, 49, 12127-12134 , 123, 49, 12127-12134 Journal of the American Chemical Society, 123, 49, 12127-12134 2001/12/12 Refereed English Disclose to all
S. Futaki; W. Ohashi; T. Suzuki; M. Niwa; S. Tanaka; K. Ueda; H. Harashima; Y. Sugiura S. Futaki; W. Ohashi; T. Suzuki; M. Niwa; S. Tanaka; K. Ueda; H. Harashima; Y. Sugiura Stearylated arginine-rich peptides: A new class of transfection systems Stearylated arginine-rich peptides: A new class of transfection systems Bioconjugate Chemistry, 12, 6, 1005-1011 , 12, 6, 1005-1011 Bioconjugate Chemistry, 12, 6, 1005-1011 2001/11 Refereed English Disclose to all
K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Part II. Total synthesis of human big gastrin-II and its C-terminal glycine-extended peptide (G34-Gly sulfate) by the solid-phase segment condensation approach Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Part II. Total synthesis of human big gastrin-II and its C-terminal glycine-extended peptide (G34-Gly sulfate) by the solid-phase segment condensation approach Chemical and Pharmaceutical Bulletin, 49, 8, 958-963 , 49, 8, 958-963 Chemical and Pharmaceutical Bulletin, 49, 8, 958-963 2001/08 Refereed English Disclose to all
S. Futaki; M. Araki; T. Kiwada; I. Nakase; Y. Sugiura S. Futaki; M. Araki; T. Kiwada; I. Nakase; Y. Sugiura A \\'Cassette\\' RNase: Site-selective cleavage of RNA by RNase S equipped with RNA-recognition segment A \\'Cassette\\' RNase: Site-selective cleavage of RNA by RNase S equipped with RNA-recognition segment Bioorganic and Medicinal Chemistry Letters, 11, 9, 1165-1168 , 11, 9, 1165-1168 Bioorganic and Medicinal Chemistry Letters, 11, 9, 1165-1168 2001/05/07 Refereed English Disclose to all
M. Takikawa; M. Kamada; M. Maegawa; S. Yamano; M. Irahara; T. Aono; S. Futaki; Y. Ohmoto; S.S. Koide M. Takikawa; M. Kamada; M. Maegawa; S. Yamano; M. Irahara; T. Aono; S. Futaki; Y. Ohmoto; S.S. Koide Evaluation of two sperm antigens, rSMP-B and YWK-II, as targets for immunocontraception Evaluation of two sperm antigens, rSMP-B and YWK-II, as targets for immunocontraception Zygote, 9, 2, 145-151 , 9, 2, 145-151 Zygote, 9, 2, 145-151 2001/05 Refereed English Disclose to all
N. Arakaki; Y. Ueyama; M. Hirose; T. Himeda; H. Shibata; S. Futaki; K. Kitagawa; T. Higuti N. Arakaki; Y. Ueyama; M. Hirose; T. Himeda; H. Shibata; S. Futaki; K. Kitagawa; T. Higuti Stoichiometry of subunit e in rat liver mitochondrial H<sup>+</sup>-ATP synthase and membrane topology of its putative Ca<sup>2+</sup>-dependent regulatory region Stoichiometry of subunit e in rat liver mitochondrial H<sup>+</sup>-ATP synthase and membrane topology of its putative Ca<sup>2+</sup>-dependent regulatory region Biochimica et Biophysica Acta - Bioenergetics, 1504, 2-3, 220-228 , 1504, 2-3, 220-228 Biochimica et Biophysica Acta - Bioenergetics, 1504, 2-3, 220-228 2001/04/02 Refereed English Disclose to all
S. Futaki; T. Suzuki; W. Ohashi; T. Yagami; S. Tanaka; K. Ueda; Y. Sugiura S. Futaki; T. Suzuki; W. Ohashi; T. Yagami; S. Tanaka; K. Ueda; Y. Sugiura Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery Journal of Biological Chemistry, 276, 8, 5836-5840 , 276, 8, 5836-5840 Journal of Biological Chemistry, 276, 8, 5836-5840 2001/02/23 Refereed English Disclose to all
S. Futaki; Z. Youjun; Y. Sugiura S. Futaki; Z. Youjun; Y. Sugiura Detecting a tag on a channel opening: Blockage of the biotinylated channels by streptavidin Detecting a tag on a channel opening: Blockage of the biotinylated channels by streptavidin Tetrahedron Letters, 42, 8, 1563-1565 , 42, 8, 1563-1565 Tetrahedron Letters, 42, 8, 1563-1565 2001/02/19 Refereed English Disclose to all
K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki; M. Kogire; J. Ida; K. Inoue K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki; M. Kogire; J. Ida; K. Inoue Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Total synthesis of human big gastrin-II and cholecystokinin (CCK)-39 Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Total synthesis of human big gastrin-II and cholecystokinin (CCK)-39 Journal of Organic Chemistry, 66, 1, 1-10 , 66, 1, 1-10 Journal of Organic Chemistry, 66, 1, 1-10 2001/01/12 Refereed English Disclose to all
M. Kamada; M. Takikawa; M. Maegawa; S. Yamamoto; S. Yamanoa; M. Irahara; T. Aono; S. Futaki; Y. Ohmoto; S. Koide M. Kamada; M. Takikawa; M. Maegawa; S. Yamamoto; S. Yamanoa; M. Irahara; T. Aono; S. Futaki; Y. Ohmoto; S. Koide Specific cytotoxicity of antibody to YAL-198, a sperm antigen peptide, to murine zygote Specific cytotoxicity of antibody to YAL-198, a sperm antigen peptide, to murine zygote Systems Biology in Reproductive Medicine, 47, 2, 89-96 , 47, 2, 89-96 Systems Biology in Reproductive Medicine, 47, 2, 89-96 2001 Refereed English Disclose to all
T. Yagami; K. Kitagawa; C. Aida; H. Fujiwara; S. Futaki T. Yagami; K. Kitagawa; C. Aida; H. Fujiwara; S. Futaki Stabilization of a tyrosine O-sulfate residue by a cationic functional group: Formation of a conjugate acid-base pair Stabilization of a tyrosine O-sulfate residue by a cationic functional group: Formation of a conjugate acid-base pair Journal of Peptide Research, 56, 4, 239-249 , 56, 4, 239-249 Journal of Peptide Research, 56, 4, 239-249 2000/10 Refereed English Disclose to all
Y. Hori; K. Suzuki; Y. Okuno; M. Nagaoka; S. Futaki; Y. Sugiura Y. Hori; K. Suzuki; Y. Okuno; M. Nagaoka; S. Futaki; Y. Sugiura Artificial zinc finger peptide containing a novel his<sub>4</sub> domain Artificial zinc finger peptide containing a novel his<sub>4</sub> domain Journal of the American Chemical Society, 122, 32, 7648-7653 , 122, 32, 7648-7653 Journal of the American Chemical Society, 122, 32, 7648-7653 2000/08/16 Refereed English Disclose to all
H. Monoi; S. Futaki; S.-I. Kugimiya; H. Minakata; K. Yoshihara H. Monoi; S. Futaki; S.-I. Kugimiya; H. Minakata; K. Yoshihara Poly-L-glutamine forms cation channels: Relevance to the pathogenesis of the polyglutamine diseases Poly-L-glutamine forms cation channels: Relevance to the pathogenesis of the polyglutamine diseases Biophysical Journal, 78, 6, 2892-2899 , 78, 6, 2892-2899 Biophysical Journal, 78, 6, 2892-2899 2000/06 Refereed English Disclose to all
M. Kamada; S. Yamamoto; M. Takikawa; K. Kunimi; M. Maegawa; S. Futaki; Y. Ohmoto; T. Aono; S.S. Koide M. Kamada; S. Yamamoto; M. Takikawa; K. Kunimi; M. Maegawa; S. Futaki; Y. Ohmoto; T. Aono; S.S. Koide Identification of the human sperm protein that interacts with sperm- immobilizing antibodies in the sera of infertile women Identification of the human sperm protein that interacts with sperm- immobilizing antibodies in the sera of infertile women Fertility and Sterility, 72, 4, 691-695 , 72, 4, 691-695 Fertility and Sterility, 72, 4, 691-695 1999/10 Refereed English Disclose to all
S. Futaki; M. Aoki; T. Ishikawa; F. Kondo; T. Asahara; M. Niwa; Y. Nakaya; T. Yagami; K. Kitagawa S. Futaki; M. Aoki; T. Ishikawa; F. Kondo; T. Asahara; M. Niwa; Y. Nakaya; T. Yagami; K. Kitagawa Chemical ligation to obtain proteins comprising helices with individual amino acid sequences Chemical ligation to obtain proteins comprising helices with individual amino acid sequences Bioorganic and Medicinal Chemistry, 7, 1, 187-192 , 7, 1, 187-192 Bioorganic and Medicinal Chemistry, 7, 1, 187-192 1999/01 Refereed English Disclose to all
S. Futaki S. Futaki Peptide synthesis aiming at elucidation and creation of protein functions Peptide synthesis aiming at elucidation and creation of protein functions Yakugaku Zasshi, 118, 11, 493-510 , 118, 11, 493-510 Yakugaku Zasshi, 118, 11, 493-510 1998/11 Refereed English Disclose to all
R. Tachibana; H. Harashima; M. Shono; M. Azumano; M. Niwa; S. Futaki; H. Kiwada R. Tachibana; H. Harashima; M. Shono; M. Azumano; M. Niwa; S. Futaki; H. Kiwada Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: Qualitative and quantitative evaluation of intracellular trafficking Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: Qualitative and quantitative evaluation of intracellular trafficking Biochemical and Biophysical Research Communications, 251, 2, 538-544 , 251, 2, 538-544 Biochemical and Biophysical Research Communications, 251, 2, 538-544 1998/10/20 Refereed English Disclose to all
M. Kamada; H. Mori; N. Maeda; S. Yamamoto; K. Kunimi; M. Takikawa; M. Maegawa; T. Aono; S. Futaki; S.S. Koide M. Kamada; H. Mori; N. Maeda; S. Yamamoto; K. Kunimi; M. Takikawa; M. Maegawa; T. Aono; S. Futaki; S.S. Koide β-Microseminoprotein/prostatic secretory protein is a member of immunoglobulin binding factor family β-Microseminoprotein/prostatic secretory protein is a member of immunoglobulin binding factor family Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1388, 1, 101-110 , 1388, 1, 101-110 Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1388, 1, 101-110 1998/10/14 Refereed English Disclose to all
H. Mori; M. Kamada; M. Maegawa; S. Yamamoto; T. Aono; S. Futaki; M. Yano; H. Kido; S.S. Koide H. Mori; M. Kamada; M. Maegawa; S. Yamamoto; T. Aono; S. Futaki; M. Yano; H. Kido; S.S. Koide Enzymatic activation of immunoglobulin binding factor in female reproductive tract Enzymatic activation of immunoglobulin binding factor in female reproductive tract Biochemical and Biophysical Research Communications, 246, 2, 409-413 , 246, 2, 409-413 Biochemical and Biophysical Research Communications, 246, 2, 409-413 1998/05/19 Refereed English Disclose to all
S. Futaki S. Futaki Creation of ion channel function using synthetic peptides Creation of ion channel function using synthetic peptides Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 56, 2, 125-133 , 56, 2, 125-133 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 56, 2, 125-133 1998/02 Refereed English Disclose to all
S. Futaki S. Futaki Peptide ion channels: Design and creation of function Peptide ion channels: Design and creation of function Biopolymers - Peptide Science Section, 47, 1, 75-81 , 47, 1, 75-81 Biopolymers - Peptide Science Section, 47, 1, 75-81 1998 Refereed English Disclose to all
Y. Tsutsumishita; T. Onda; K. Okada; M. Takeda; H. Endou; S. Futaki; M. Niwa Y. Tsutsumishita; T. Onda; K. Okada; M. Takeda; H. Endou; S. Futaki; M. Niwa Involvement of H<sub>2</sub>O<sub>2</sub> production in cisplatin-induced nephrotoxicity Involvement of H<sub>2</sub>O<sub>2</sub> production in cisplatin-induced nephrotoxicity Biochemical and Biophysical Research Communications, 242, 2, 310-312 , 242, 2, 310-312 Biochemical and Biophysical Research Communications, 242, 2, 310-312 1998 Refereed English Disclose to all
M. Niwa; N. Nakamura; K. Kitajima; M. Ueda; Y. Tsutsumishita; S. Futaki; Y. Takaishi M. Niwa; N. Nakamura; K. Kitajima; M. Ueda; Y. Tsutsumishita; S. Futaki; Y. Takaishi Benzoquinones inhibit the expression of inducible nitric oxide synthase gene Benzoquinones inhibit the expression of inducible nitric oxide synthase gene Biochemical and Biophysical Research Communications, 239, 2, 367-371 , 239, 2, 367-371 Biochemical and Biophysical Research Communications, 239, 2, 367-371 1997/10/20 Refereed English Disclose to all
S. Futaki; M. Aoki; M. Fukuda; F. Kondo; M. Niwa; K. Kitagawa; Y. Nakaya S. Futaki; M. Aoki; M. Fukuda; F. Kondo; M. Niwa; K. Kitagawa; Y. Nakaya Assembling of the four individual helices corresponding to the transmembrane segments (S4 in repeat I-IV) ofthe sodium channel Assembling of the four individual helices corresponding to the transmembrane segments (S4 in repeat I-IV) ofthe sodium channel Tetrahedron Letters, 38, 40, 7071-7074 , 38, 40, 7071-7074 Tetrahedron Letters, 38, 40, 7071-7074 1997/10/06 Refereed English Disclose to all
S. Futaki; K. Sogawa; J. Maruyama; T. Asahara; M. Niwa; H. Hojo S. Futaki; K. Sogawa; J. Maruyama; T. Asahara; M. Niwa; H. Hojo Preparation of peptide thioesters using Fmoc-solid-phase peptide synthesis and its application to the construction of a template-assembled synthetic protein (TASP) Preparation of peptide thioesters using Fmoc-solid-phase peptide synthesis and its application to the construction of a template-assembled synthetic protein (TASP) Tetrahedron Letters, 38, 35, 6237-6240 , 38, 35, 6237-6240 Tetrahedron Letters, 38, 35, 6237-6240 1997/09/01 Refereed English Disclose to all
S. Futaki; T. Ishikawa; M. Niwa; K. Kitagawa; T. Yagami S. Futaki; T. Ishikawa; M. Niwa; K. Kitagawa; T. Yagami Embodying a stable α-helical protein structure through efficient chemical ligation via thioether formation Embodying a stable α-helical protein structure through efficient chemical ligation via thioether formation Bioorganic and Medicinal Chemistry, 5, 9, 1883-1891 , 5, 9, 1883-1891 Bioorganic and Medicinal Chemistry, 5, 9, 1883-1891 1997/09 Refereed English Disclose to all
S. Futaki; K. Kitagawa S. Futaki; K. Kitagawa Peptide-unit assembling via disulfide cross-linking: A versatile approach which enables the creation of artificial proteins comprising helices with different amino acid sequences Peptide-unit assembling via disulfide cross-linking: A versatile approach which enables the creation of artificial proteins comprising helices with different amino acid sequences Tetrahedron, 53, 22, 7479-7492 , 53, 22, 7479-7492 Tetrahedron, 53, 22, 7479-7492 1997/06/02 Refereed English Disclose to all
K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki K. Kitagawa; C. Aida; H. Fujiwara; T. Yagami; S. Futaki Efficient solid-phase synthesis of sulfated tyrosine-containing peptides using 2-chlorotrityl resin: Facile synthesis of gastrin/cholecystokinin peptides Efficient solid-phase synthesis of sulfated tyrosine-containing peptides using 2-chlorotrityl resin: Facile synthesis of gastrin/cholecystokinin peptides Tetrahedron Letters, 38, 4, 599-602 , 38, 4, 599-602 Tetrahedron Letters, 38, 4, 599-602 1997/01/27 Refereed English Disclose to all
M. Niwa; Y. Kawai; N. Nakamura; S. Futaki M. Niwa; Y. Kawai; N. Nakamura; S. Futaki The structure of the promoter region for rat inducible nitric oxide synthase gene The structure of the promoter region for rat inducible nitric oxide synthase gene Life Sciences, 61, 5, PL45-PL49 , 61, 5, PL45-PL49 Life Sciences, 61, 5, PL45-PL49 1997 Refereed English Disclose to all
K. Kunimi; M. Takikawa; S. Yamamoto; H. Mori; M. Maegawa; M. Kamada; T. Aono; S. Futaki; M. Niwa; S.S. Koide K. Kunimi; M. Takikawa; S. Yamamoto; H. Mori; M. Maegawa; M. Kamada; T. Aono; S. Futaki; M. Niwa; S.S. Koide Expression of immunoglobulin binding factor mRNA in uterine cervical gland Expression of immunoglobulin binding factor mRNA in uterine cervical gland Journal of Reproductive Immunology, 34, 1, 43-44 , 34, 1, 43-44 Journal of Reproductive Immunology, 34, 1, 43-44 1997 Refereed English Disclose to all
M. Niwa; K. Kitajima; N. Nakamira; S. Futaki M. Niwa; K. Kitajima; N. Nakamira; S. Futaki Benzoquinones inhibit indicible nitric oxide synthase mRNA expression Benzoquinones inhibit indicible nitric oxide synthase mRNA expression FASEB Journal, 11, 9, A934 , 11, 9, A934 FASEB Journal, 11, 9, A934 1997 Refereed English Disclose to all
Y. Tsutsumishita; Y. Kawai; H. Takahara; T. Onda; J. Miyoshi; S. Futaki; M. Niwa Y. Tsutsumishita; Y. Kawai; H. Takahara; T. Onda; J. Miyoshi; S. Futaki; M. Niwa Sequence analysis of inducible nitric oxide synthase in rat kidney, lung, and uterus Sequence analysis of inducible nitric oxide synthase in rat kidney, lung, and uterus Biological and Pharmaceutical Bulletin, 19, 10, 1374-1376 , 19, 10, 1374-1376 Biological and Pharmaceutical Bulletin, 19, 10, 1374-1376 1996/10 Refereed English Disclose to all
H. Yokoi; Y. Tsuruo; T. Miyamoto; K. Kitagawa; S. Futaki; K. Ishimura H. Yokoi; Y. Tsuruo; T. Miyamoto; K. Kitagawa; S. Futaki; K. Ishimura Steroid 5α-reductase type 1 immunolocalized in the anterior pituitary of intact and castrated male rats Steroid 5α-reductase type 1 immunolocalized in the anterior pituitary of intact and castrated male rats Histochemistry and Cell Biology, 106, 4, 359-366 , 106, 4, 359-366 Histochemistry and Cell Biology, 106, 4, 359-366 1996/10 Refereed English Disclose to all
M. Niwa; Y. Tsutsumishita; Y. Kawai; H. Takahara; N. Nakamura; S. Futaki; Y. Takaishi; W. Kondoh; H. Moritoki M. Niwa; Y. Tsutsumishita; Y. Kawai; H. Takahara; N. Nakamura; S. Futaki; Y. Takaishi; W. Kondoh; H. Moritoki Suppression of inducible nitric oxide synthase mRNA expression by tryptoquinone A Suppression of inducible nitric oxide synthase mRNA expression by tryptoquinone A Biochemical and Biophysical Research Communications, 224, 2, 579-585 , 224, 2, 579-585 Biochemical and Biophysical Research Communications, 224, 2, 579-585 1996/07/16 Refereed English Disclose to all
Y. Tsuruo; T. Miyamoto; H. Yokoi; K. Kitagawa; S. Futaki; K. Ishimura Y. Tsuruo; T. Miyamoto; H. Yokoi; K. Kitagawa; S. Futaki; K. Ishimura Immunohistochemical presence of 5α-reductase rat type 1-containing cells in the rat brain Immunohistochemical presence of 5α-reductase rat type 1-containing cells in the rat brain Brain Research, 722, 1-2, 207-211 , 722, 1-2, 207-211 Brain Research, 722, 1-2, 207-211 1996/05/25 Refereed English Disclose to all
T. Miyamoto; S. Kagawa; K. Kitagawa; S. Futaki; H. Yokoi; Y. Tsuruo; K. Ishimura T. Miyamoto; S. Kagawa; K. Kitagawa; S. Futaki; H. Yokoi; Y. Tsuruo; K. Ishimura Immunocytochemical localization of 5α-reductase type 1 in the prostate of normal and castrated rats Immunocytochemical localization of 5α-reductase type 1 in the prostate of normal and castrated rats Histochemistry and Cell Biology, 105, 2, 101-109 , 105, 2, 101-109 Histochemistry and Cell Biology, 105, 2, 101-109 1996/02 Refereed English Disclose to all
S. Futaki; T. Ishikawa; M. Niwa; T. Yagami; K. Kitagawa S. Futaki; T. Ishikawa; M. Niwa; T. Yagami; K. Kitagawa Pseudo-symmetrical protein: Construction of a four-helix-bundle protein with four intramolecular disulfide cross-linkings Pseudo-symmetrical protein: Construction of a four-helix-bundle protein with four intramolecular disulfide cross-linkings Tetrahedron Letters, 37, 2, 201-204 , 37, 2, 201-204 Tetrahedron Letters, 37, 2, 201-204 1996/01/08 Refereed English Disclose to all
H. Negishi; Y.K. Jaiswal; S. Yamamoto; M. Kamada; S. Futaki; S.S. Koide H. Negishi; Y.K. Jaiswal; S. Yamamoto; M. Kamada; S. Futaki; S.S. Koide Impaired fertility in female rats immunized with synthetic peptide segments of two sperm proteins Impaired fertility in female rats immunized with synthetic peptide segments of two sperm proteins Biochemical Archives, 12, 2, 89-94 , 12, 2, 89-94 Biochemical Archives, 12, 2, 89-94 1996 Refereed English Disclose to all
YAGAMI, T; KITAGAWA, K; FUTAKI, S YAGAMI, T; KITAGAWA, K; FUTAKI, S ANALYSIS OF SULFATED TYROSINE-CONTAINING PEPTIDES BY LIQUID SECONDARY-ION MASS-SPECTROMETRY WITH CONSTANT NEUTRAL-LOSS (80 AMU) SCANNING ANALYSIS OF SULFATED TYROSINE-CONTAINING PEPTIDES BY LIQUID SECONDARY-ION MASS-SPECTROMETRY WITH CONSTANT NEUTRAL-LOSS (80 AMU) SCANNING ANALYTICAL SCIENCES, 11, 6, 1025-1028 , 11, 6, 1025-1028 ANALYTICAL SCIENCES, 11, 6, 1025-1028 1995/12 Refereed English Disclose to all
S. Futaki; T. Ishikawa; M. Niwa; K. Kitagawa; T. Yagami S. Futaki; T. Ishikawa; M. Niwa; K. Kitagawa; T. Yagami Peptide-unit assembling using S-alkylation: A highly denaturation resistant protein was obtained Peptide-unit assembling using S-alkylation: A highly denaturation resistant protein was obtained Tetrahedron Letters, 36, 29, 5203-5206 , 36, 29, 5203-5206 Tetrahedron Letters, 36, 29, 5203-5206 1995/07/17 Refereed English Disclose to all
T. Yagami; K. Kitagawa; S. Futaki T. Yagami; K. Kitagawa; S. Futaki Liquid secondary-ion mass spectrometry of peptides containing multiple tyrosine-O-sulfates Liquid secondary-ion mass spectrometry of peptides containing multiple tyrosine-O-sulfates Rapid Communications in Mass Spectrometry, 9, 14, 1335-1341 , 9, 14, 1335-1341 Rapid Communications in Mass Spectrometry, 9, 14, 1335-1341 1995 Refereed English Disclose to all
M. Kamada; N. Maeda; M. Maegawa; H. Mori; S. Yamamoto; T. Aono; M. Muraguchi; Y. Ohmoto; S. Futaki; F. Ogushi; S. Sone; H. Kanayama; S. Kagawa; S.S. Koide M. Kamada; N. Maeda; M. Maegawa; H. Mori; S. Yamamoto; T. Aono; M. Muraguchi; Y. Ohmoto; S. Futaki; F. Ogushi; S. Sone; H. Kanayama; S. Kagawa; S.S. Koide Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies Detection of immunoglobulin binding factor by enzyme-linked immunosorbent assay using two monoclonal antibodies Biochemistry and Molecular Biology International, 34, 4, 837-844 , 34, 4, 837-844 Biochemistry and Molecular Biology International, 34, 4, 837-844 1994/10 Refereed English Disclose to all
N. Tsuzuki; T. Hama; M. Kawada; A. Hasui; R. Konishi; S. Shiwa; Y. Ochi; S. Futaki; K. Kitagawa N. Tsuzuki; T. Hama; M. Kawada; A. Hasui; R. Konishi; S. Shiwa; Y. Ochi; S. Futaki; K. Kitagawa Adamantane as a brain-directed drug carrier for poorly absorbed drug. 2. AZT derivatives conjugated with the 1-adamantane moiety Adamantane as a brain-directed drug carrier for poorly absorbed drug. 2. AZT derivatives conjugated with the 1-adamantane moiety Journal of Pharmaceutical Sciences, 83, 4, 481-484 , 83, 4, 481-484 Journal of Pharmaceutical Sciences, 83, 4, 481-484 1994/04 Refereed English Disclose to all
N. Maeda; M. Kamada; T. Daitoh; M. Maegawa; K. Hirano; T. Aono; T. Shiotsu; H. Kanayama; S. Kagawa; S. Futaki; M. Muraguchi; Y. Ohmoto; Zhi Guo Liang; S.S. Koide N. Maeda; M. Kamada; T. Daitoh; M. Maegawa; K. Hirano; T. Aono; T. Shiotsu; H. Kanayama; S. Kagawa; S. Futaki; M. Muraguchi; Y. Ohmoto; Zhi Guo Liang; S.S. Koide Immunoglobulin binding factor: A new tumor marker for prostatic tumors Immunoglobulin binding factor: A new tumor marker for prostatic tumors Prostate, 24, 3, 125-130 , 24, 3, 125-130 Prostate, 24, 3, 125-130 1994/03 Refereed English Disclose to all
S. Futaki; K. Kitagawa S. Futaki; K. Kitagawa Peptide-unit assembling using disulfide cross-linking: A new approach for construction of protein models Peptide-unit assembling using disulfide cross-linking: A new approach for construction of protein models Tetrahedron Letters, 35, 8, 1267-1270 , 35, 8, 1267-1270 Tetrahedron Letters, 35, 8, 1267-1270 1994/02/21 Refereed English Disclose to all
K. Kitagawa; S. Futaki; T. Yagami; S. Sumi; K. Inoue K. Kitagawa; S. Futaki; T. Yagami; S. Sumi; K. Inoue Solid-phase synthesis of cionin, a protochordate-derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono- tyrosine-sulfate-containing derivatives Solid-phase synthesis of cionin, a protochordate-derived octapeptide related to the gastrin/cholecystokinin family of peptides, and its mono- tyrosine-sulfate-containing derivatives International Journal of Peptide and Protein Research, 43, 2, 190-200 , 43, 2, 190-200 International Journal of Peptide and Protein Research, 43, 2, 190-200 1994/02 Refereed English Disclose to all
N. Maeda; M. Kamada; T. Daitoh; T. Aono; S. Futaki; Z.G. Liang; S.S. Koide N. Maeda; M. Kamada; T. Daitoh; T. Aono; S. Futaki; Z.G. Liang; S.S. Koide Immunoglobulin binding factor in human seminal plasma: Immunological function Immunoglobulin binding factor in human seminal plasma: Immunological function Archives of Andrology, 31, 1, 31-36 , 31, 1, 31-36 Archives of Andrology, 31, 1, 31-36 1993/07 Refereed English Disclose to all
M.B. Bhatia; S. Futaki; H. Ueno; J.M. Manning; D. Ringe; T. Yoshimura; K. Soda M.B. Bhatia; S. Futaki; H. Ueno; J.M. Manning; D. Ringe; T. Yoshimura; K. Soda Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase Kinetic and stereochemical comparison of wild-type and active-site K145Q mutant enzyme of bacterial D-amino acid transaminase Journal of Biological Chemistry, 268, 10, 6932-6938 , 268, 10, 6932-6938 Journal of Biological Chemistry, 268, 10, 6932-6938 1993/04/05 Refereed English Disclose to all
S. Futaki; T. Taike; T. Akita; K. Kitagawa S. Futaki; T. Taike; T. Akita; K. Kitagawa Syntheses of two tyrosine-sulphate containing peptides. Leucosulfakinin (LSK)-II and cholecystokinin (CCK)-12, using the 0-p-(methylsulphinyl)benzyl serine for the selective sulphation of tyrosine Syntheses of two tyrosine-sulphate containing peptides. Leucosulfakinin (LSK)-II and cholecystokinin (CCK)-12, using the 0-p-(methylsulphinyl)benzyl serine for the selective sulphation of tyrosine Tetrahedron, 48, 41, 8899-8914 , 48, 41, 8899-8914 Tetrahedron, 48, 41, 8899-8914 1992/10/09 Refereed English Disclose to all
A. Martinez Del Pozo; T. Yoshimura; M.B. Bhatia; S. Futaki; J.M. Manning; D. Ringe; K. Soda A. Martinez Del Pozo; T. Yoshimura; M.B. Bhatia; S. Futaki; J.M. Manning; D. Ringe; K. Soda Inactivation of dimeric D-amino acid transaminase by a normal substrate through formation of an unproductive coenzyme adduct in one subunit Inactivation of dimeric D-amino acid transaminase by a normal substrate through formation of an unproductive coenzyme adduct in one subunit Biochemistry, 31, 26, 6018-6023 , 31, 26, 6018-6023 Biochemistry, 31, 26, 6018-6023 1992/07/07 Refereed English Disclose to all
K. Nishimura; K. Tanizawa; T. Yoshimura; N. Esaki; S. Futaki; J.M. Manning; K. Soda K. Nishimura; K. Tanizawa; T. Yoshimura; N. Esaki; S. Futaki; J.M. Manning; K. Soda Effect of substitution of a lysyl residue that binds pyridoxal phosphate in thermostable D-amino acid aminotransferase by arginine and alanine Effect of substitution of a lysyl residue that binds pyridoxal phosphate in thermostable D-amino acid aminotransferase by arginine and alanine Biochemistry, 30, 16, 4072-4077 , 30, 16, 4072-4077 Biochemistry, 30, 16, 4072-4077 1991/04/23 Refereed English Disclose to all
Y. Kuraishi; M. Kawamura; T. Yamaguchi; T. Houtani; S. Kawabata; S. Futaki; N. Fujii; M. Satoh Y. Kuraishi; M. Kawamura; T. Yamaguchi; T. Houtani; S. Kawabata; S. Futaki; N. Fujii; M. Satoh Intrathecal injections of galanin and its antiserum affect nociceptive response of rat to mechanical, but not thermal, stimuli Intrathecal injections of galanin and its antiserum affect nociceptive response of rat to mechanical, but not thermal, stimuli Pain, 44, 3, 321-324 , 44, 3, 321-324 Pain, 44, 3, 321-324 1991/03 Refereed English Disclose to all
N. Tsuzuki; T. Hama; T. Hibi; R. Konishi; S. Futaki; K. Kitagawa N. Tsuzuki; T. Hama; T. Hibi; R. Konishi; S. Futaki; K. Kitagawa Adamantane as a brain-directed drug carrier for poorly absorbed drug: Antinociceptive effects of [D-Ala<sup>2</sup>] Leu-enkephalin derivatives conjugated with the 1-adamantane moiety Adamantane as a brain-directed drug carrier for poorly absorbed drug: Antinociceptive effects of [D-Ala<sup>2</sup>] Leu-enkephalin derivatives conjugated with the 1-adamantane moiety Biochemical Pharmacology, 41, 4, R5-R8 , 41, 4, R5-R8 Biochemical Pharmacology, 41, 4, R5-R8 1991 Refereed English Disclose to all
S. Futaki; H. Ueno; A. Martinez Del Pozo; M.A. Pospischil; J.M. Manning; D. Ringe; B. Stoddard; K. Tanizawa; T. Yoshimura; K. Soda S. Futaki; H. Ueno; A. Martinez Del Pozo; M.A. Pospischil; J.M. Manning; D. Ringe; B. Stoddard; K. Tanizawa; T. Yoshimura; K. Soda Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase: Effects of exogenous amines on the slow formation of intermediates Substitution of glutamine for lysine at the pyridoxal phosphate binding site of bacterial D-amino acid transaminase: Effects of exogenous amines on the slow formation of intermediates Journal of Biological Chemistry, 265, 36, 22306-22312 , 265, 36, 22306-22312 Journal of Biological Chemistry, 265, 36, 22306-22312 1990/12/25 Refereed English Disclose to all
S. Futaki; T. Taike; T. Yagami; T. Ogawa; T. Akita; K. Kitagawa S. Futaki; T. Taike; T. Yagami; T. Ogawa; T. Akita; K. Kitagawa Use of dimethylformamide-sulphur trioxide complex as a sulphating agent of tyrosine Use of dimethylformamide-sulphur trioxide complex as a sulphating agent of tyrosine Journal of the Chemical Society, Perkin Transactions 1, 6, 1739-1744 , 6, 1739-1744 Journal of the Chemical Society, Perkin Transactions 1, 6, 1739-1744 1990/06 Refereed English Disclose to all
S. Futaki; T. Yagami; T. Taike; T. Akita; K. Kitagawa S. Futaki; T. Yagami; T. Taike; T. Akita; K. Kitagawa Sulphur trioxide/thiol: A novel system for the reduction of methionine sulphoxide Sulphur trioxide/thiol: A novel system for the reduction of methionine sulphoxide Journal of the Chemical Society, Perkin Transactions 1, 3, 653-658 , 3, 653-658 Journal of the Chemical Society, Perkin Transactions 1, 3, 653-658 1990/03 Refereed English Disclose to all
T. Oda; S. Futaki; K. Kitagawa; Y. Yoshihara; I. Tani; T. Higuti T. Oda; S. Futaki; K. Kitagawa; Y. Yoshihara; I. Tani; T. Higuti Orientation of chargerin II (A6L) in the ATP synthase of rat liver mitochondria determined with antibodies against peptides of the protein Orientation of chargerin II (A6L) in the ATP synthase of rat liver mitochondria determined with antibodies against peptides of the protein Biochemical and Biophysical Research Communications, 165, 1, 449-456 , 165, 1, 449-456 Biochemical and Biophysical Research Communications, 165, 1, 449-456 1989/11/30 Refereed English Disclose to all
S. Ono; K. Kitagawa; S. Futaki; S. Kiyama; Y. Ooi; T. Akita; S. Higashide; K. Inoue; S. Sumi; T. Tobe S. Ono; K. Kitagawa; S. Futaki; S. Kiyama; Y. Ooi; T. Akita; S. Higashide; K. Inoue; S. Sumi; T. Tobe Solution synthesis of human neuropeptide Y (hNPY) Solution synthesis of human neuropeptide Y (hNPY) Chemical and Pharmaceutical Bulletin, 37, 7, 1925-1929 , 37, 7, 1925-1929 Chemical and Pharmaceutical Bulletin, 37, 7, 1925-1929 1989/07 Refereed English Disclose to all
S. Ono; S. Kiyama; K. Kitagawa; S. Futaki; T. Nakamura; T. Taike; T. Akita; S. Sumi; K. Inoue; M. Fujimura; T. Tobe; H. Yajima S. Ono; S. Kiyama; K. Kitagawa; S. Futaki; T. Nakamura; T. Taike; T. Akita; S. Sumi; K. Inoue; M. Fujimura; T. Tobe; H. Yajima Application of the trimethylsilyl trifluoromethanesulfonate deprotecting procedure for the synthesis of porcine peptide YY (PYY) Application of the trimethylsilyl trifluoromethanesulfonate deprotecting procedure for the synthesis of porcine peptide YY (PYY) International Journal of Peptide and Protein Research, 33, 1, 29-38 , 33, 1, 29-38 International Journal of Peptide and Protein Research, 33, 1, 29-38 1989/01 Refereed English Disclose to all
S. Futaki; T. Taike; T. Yagami; T. Akita; K. Kitagawa S. Futaki; T. Taike; T. Yagami; T. Akita; K. Kitagawa Facile reduction of methionine sulfoxide with sulfur trioxide/thiol system Facile reduction of methionine sulfoxide with sulfur trioxide/thiol system Tetrahedron Letters, 30, 33, 4411-4412 , 30, 33, 4411-4412 Tetrahedron Letters, 30, 33, 4411-4412 1989 Refereed English Disclose to all
N. Fujii; S. Futaki; S. Funakoshi; K. Akaji; H. Morimoto; R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; T. Tobe; M. Aono; M. Matsuda; H. Narusawa; M. Moriga; H. Yajima N. Fujii; S. Futaki; S. Funakoshi; K. Akaji; H. Morimoto; R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; T. Tobe; M. Aono; M. Matsuda; H. Narusawa; M. Moriga; H. Yajima Studies on peptides. CLX. Synthesis of a 33-residue peptide corresponding to the entire amino acid sequence of human cholecystokinin (hCCK-33) Studies on peptides. CLX. Synthesis of a 33-residue peptide corresponding to the entire amino acid sequence of human cholecystokinin (hCCK-33) Chemical and Pharmaceutical Bulletin, 36, 9, 3281-3291 , 36, 9, 3281-3291 Chemical and Pharmaceutical Bulletin, 36, 9, 3281-3291 1988/09 Refereed English Disclose to all
R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; S. Futaki; N. Fujii; H. Yajima; T. Tobe R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; S. Futaki; N. Fujii; H. Yajima; T. Tobe Role of sulphated tyrosine residue in influencing the biologic activity of human cholecystokinin-33 Role of sulphated tyrosine residue in influencing the biologic activity of human cholecystokinin-33 Biochemical and Biophysical Research Communications, 153, 3, 1209-1213 , 153, 3, 1209-1213 Biochemical and Biophysical Research Communications, 153, 3, 1209-1213 1988/06/30 Refereed English Disclose to all
R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; S. Futaki; N. Fujii; H. Yajima; T. Tobe R. Doi; K. Inoue; M. Kogire; S. Sumi; M. Yun; S. Futaki; N. Fujii; H. Yajima; T. Tobe Effect of synthetic human cholecystokinin-33 on exocrine pancreas Effect of synthetic human cholecystokinin-33 on exocrine pancreas Biochemical and Biophysical Research Communications, 150, 3, 1251-1255 , 150, 3, 1251-1255 Biochemical and Biophysical Research Communications, 150, 3, 1251-1255 1988/02/15 Refereed English Disclose to all
F.A. Robey; K. Ohura; S. Futaki; N. Fujii; H. Yajima; N. Goldman; K.D. Jones; S. Wahl F.A. Robey; K. Ohura; S. Futaki; N. Fujii; H. Yajima; N. Goldman; K.D. Jones; S. Wahl Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity Proteolysis of human C-reactive protein produces peptides with potent immunomodulating activity Journal of Biological Chemistry, 262, 15, 7053-7057 , 262, 15, 7053-7057 Journal of Biological Chemistry, 262, 15, 7053-7057 1987/05/25 Refereed English Disclose to all
Iwasaki Y, Fujita T, Yabe H, Kitagawa K, Futaki S, Matsuzaki T, Akita T Iwasaki Y, Fujita T, Yabe H, Kitagawa K, Futaki S, Matsuzaki T, Akita T Synthesis and Antifungal Activity of Azole Derivatives of 2- Propen-1-One Synthesis and Antifungal Activity of Azole Derivatives of 2- Propen-1-One J. Pharm. Sci., 76, S157-S157 J. Pharm. Sci., 76, S157-S157 1987 Refereed English Disclose to all
H. Yajima; S. Futaki; N. Fujii; K. Akaji; S. Funakoshi; M. Sakurai; S. Katakura; K. Inoue; R. Hosotani; T. Tobe; T. Segawa; A. Inoue; K. Tatemoto; V. Mutt H. Yajima; S. Futaki; N. Fujii; K. Akaji; S. Funakoshi; M. Sakurai; S. Katakura; K. Inoue; R. Hosotani; T. Tobe; T. Segawa; A. Inoue; K. Tatemoto; V. Mutt Synthesis of galanin, a new gastrointestinal polypeptide Synthesis of galanin, a new gastrointestinal polypeptide Journal of the Chemical Society, Chemical Communications, 13, 877-878 , 13, 877-878 Journal of the Chemical Society, Chemical Communications, 13, 877-878 1985 Refereed English Disclose to all
Ueda, Y.; Fan-Yan Wei.; Hide, T.; Michiue, H.; Takayama, K.; Kaitsuka, T.; Nakamura, H.; Makino, K.; Kuratsu, J.; Futaki, S.; Tomizawa, K. Ueda, Y.; Fan-Yan Wei.; Hide, T.; Michiue, H.; Takayama, K.; Kaitsuka, T.; Nakamura, H.; Makino, K.; Kuratsu, J.; Futaki, S.; Tomizawa, K. Cell-penetrating D-isomer Peptides Consisting of Pas and the p53 C-terminus Induce Autophagic Cell Death of Glioma-initiating Cells Cell-penetrating D-isomer Peptides Consisting of Pas and the p53 C-terminus Induce Autophagic Cell Death of Glioma-initiating Cells Biomaterials, in press, Biomaterials, in press, Refereed English Disclose to all

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Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
R. Kawano, D. Noshiro, T. Osaki, T. Osaki, K. Kamiya, K. Asami, S. Futaki, S. Takeuchi, S. Takeuchi R. Kawano, D. Noshiro, T. Osaki, T. Osaki, K. Kamiya, K. Asami, S. Futaki, S. Takeuchi, S. Takeuchi R. Kawano, D. Noshiro, T. Osaki, T. Osaki, K. Kamiya, K. Asami, S. Futaki, S. Takeuchi, S. Takeuchi Single-stranded DNA detection via chemically modified alamethicin nanopore at single molecule level Single-stranded DNA detection via chemically modified alamethicin nanopore at single molecule level Single-stranded DNA detection via chemically modified alamethicin nanopore at single molecule level 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, 1, 32-34 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, 1, 32-34 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, 1, 32-34 2013/01/01 English Introduction and explanation (international conference proceedings) Disclose to all
今西未来 ,中村篤史、山本和俊、土居雅夫、岡村均、二木史朗 今西未来 ,中村篤史、山本和俊、土居雅夫、岡村均、二木史朗 人工DNA結合蛋白質による細胞分子時計の操作 人工DNA結合蛋白質による細胞分子時計の操作 「細胞を創る」研究会5.0 ,横浜(東京工業大学) 「細胞を創る」研究会5.0 ,横浜(東京工業大学) 2012/11/21 Refereed Japanese Disclose to all
田中 弦 ,中瀬生彦、大石真也、藤井信孝、志村和也、松岡雅雄、二木史朗 田中 弦 ,中瀬生彦、大石真也、藤井信孝、志村和也、松岡雅雄、二木史朗 マクロピノサイトーシス誘導受容体としてのCXCR4 マクロピノサイトーシス誘導受容体としてのCXCR4 第34回生体膜と薬物の相互作用シンポジウム(2012) ,京都(京都大学) 第34回生体膜と薬物の相互作用シンポジウム(2012) ,京都(京都大学) 2012/11/15 Refereed Japanese Disclose to all
山崎ちさと ,中瀬生彦、遠藤裕之、岸本沙耶、増山祥弘、二木史朗、小出隆規 山崎ちさと ,中瀬生彦、遠藤裕之、岸本沙耶、増山祥弘、二木史朗、小出隆規 コラーゲン様ペプチドのコンフォメーション依存的な細胞内への移行 コラーゲン様ペプチドのコンフォメーション依存的な細胞内への移行 第49回ペプチド討論会 ,かごしま県民交流センター(鹿児島) 第49回ペプチド討論会 ,かごしま県民交流センター(鹿児島) 2012/11/09 Refereed Japanese Disclose to all
中瀬生彦 ,片山沙綾香、奥村真也、二木史朗 中瀬生彦 ,片山沙綾香、奥村真也、二木史朗 ミトコンドリアを標的とする膜透過ペプチドの創製と活性分子の細胞内送達 ミトコンドリアを標的とする膜透過ペプチドの創製と活性分子の細胞内送達 第49回ペプチド討論会 ,かごしま県民交流センター(鹿児島) 第49回ペプチド討論会 ,かごしま県民交流センター(鹿児島) 2012/11/09 Refereed Japanese Disclose to all
大崎勝弘 ,中瀬生彦、二木史朗 大崎勝弘 ,中瀬生彦、二木史朗 ROLES OF SYNDECAN-4 AND PKCα FOR CELLULAR UPTAKE OF ARGININE-RICH PEPTIDES ROLES OF SYNDECAN-4 AND PKCα FOR CELLULAR UPTAKE OF ARGININE-RICH PEPTIDES 第49回ペプチド討論会 ,鹿児島(かごしま県民交流センター ) 第49回ペプチド討論会 ,鹿児島(かごしま県民交流センター ) 2012/11/08 Refereed Japanese Disclose to all
片山沙綾香 ,中瀬生彦、中田靖、二木史朗 片山沙綾香 ,中瀬生彦、中田靖、二木史朗 アルギニンペプチドの直接細胞膜透過を誘起するピレンブチレートの挙動と役割 アルギニンペプチドの直接細胞膜透過を誘起するピレンブチレートの挙動と役割 第49回ペプチド討論会 ,鹿児島(かごしま県民交流センター ) 第49回ペプチド討論会 ,鹿児島(かごしま県民交流センター ) 2012/11/07 Refereed Japanese Disclose to all
大崎勝弘 ,中瀬生彦、二木史朗 大崎勝弘 ,中瀬生彦、二木史朗 アルギニンペプチドの細胞内移行におけるsyndecan-4及びPKCαの寄与 アルギニンペプチドの細胞内移行におけるsyndecan-4及びPKCαの寄与 第62回日本薬学会近畿支部・大会 ,西宮(武庫川女子大学薬学部浜甲子園キャンパス) 第62回日本薬学会近畿支部・大会 ,西宮(武庫川女子大学薬学部浜甲子園キャンパス) 2012/10/20 Refereed Japanese Disclose to all
今西未来 ,中村篤史、土居雅夫、二木史朗、岡村均 今西未来 ,中村篤史、土居雅夫、二木史朗、岡村均 Period1プロモーターを標的とした人工転写因子による細胞時計のリセット Period1プロモーターを標的とした人工転写因子による細胞時計のリセット 第19回日本時間生物学会学術大会 ,札幌(北海道大学) 第19回日本時間生物学会学術大会 ,札幌(北海道大学) 2012/09/15 Refereed Japanese Disclose to all
中瀬生彦 ,片山沙綾香、奥村真也、二木史朗 中瀬生彦 ,片山沙綾香、奥村真也、二木史朗 ミトコンドリアを標的とする細胞膜透過ペプチドベクターの創製 ミトコンドリアを標的とする細胞膜透過ペプチドベクターの創製 第6回バイオ関連化学シンポジウム ,札幌(北海道大学) 第6回バイオ関連化学シンポジウム ,札幌(北海道大学) 2012/09/06 Refereed Japanese Disclose to all
中瀬生彦 ,小西雄介、上田真史、佐治英郎、二木史朗 中瀬生彦 ,小西雄介、上田真史、佐治英郎、二木史朗 In vivoにおけるアルギニンペプチドの腫瘍集積と抗癌剤送達への応用 In vivoにおけるアルギニンペプチドの腫瘍集積と抗癌剤送達への応用 第28回日本DDS学会学術集会 ,札幌(札幌コンベンションセンター) 第28回日本DDS学会学術集会 ,札幌(札幌コンベンションセンター) 2012/07/05 Refereed Japanese Disclose to all
中瀬生彦 ,大崎勝弘、奥村真也、二木史朗 中瀬生彦 ,大崎勝弘、奥村真也、二木史朗 ヘリックス相互作用で活性化可能な人工EGF受容体の創製と細胞機能制御 ヘリックス相互作用で活性化可能な人工EGF受容体の創製と細胞機能制御 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/09 Refereed Japanese Disclose to all
川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 光反応基を用いた細胞膜透過性ペプチドの細胞内移行に関与する候補タンパク質の同定の試み 光反応基を用いた細胞膜透過性ペプチドの細胞内移行に関与する候補タンパク質の同定の試み 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/08 Refereed Japanese Disclose to all
能代大輔 ,浅見耕司、二木史朗 能代大輔 ,浅見耕司、二木史朗 リポソーム内物質のリーケージを金属により制御可能なチャネルペプチドの創製 リポソーム内物質のリーケージを金属により制御可能なチャネルペプチドの創製 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/08 Refereed Japanese Disclose to all
奥彰彦 ,游晧欣、吉村智之、中瀬生彦、川端猛夫、二木史朗 奥彰彦 ,游晧欣、吉村智之、中瀬生彦、川端猛夫、二木史朗 細胞内安定型ユビキチンポリマーの創製と細胞内導入 細胞内安定型ユビキチンポリマーの創製と細胞内導入 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/07 Refereed Japanese Disclose to all
今西未来 ,辻将吾、松村一史、中屋智博、杉浦幸雄、二木史朗 今西未来 ,辻将吾、松村一史、中屋智博、杉浦幸雄、二木史朗 ジンクフィンガーの配位子置換による亜鉛濃度応答性人工転写因子の創製 ジンクフィンガーの配位子置換による亜鉛濃度応答性人工転写因子の創製 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/07 Refereed Japanese Disclose to all
村山知 ,Pujals S?lvia、二木史朗 村山知 ,Pujals S?lvia、二木史朗 Adenovirus internal protein VI由来の両親媒性ペプチドによる膜の形態変化と傷害性に関する研究 Adenovirus internal protein VI由来の両親媒性ペプチドによる膜の形態変化と傷害性に関する研究 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 日本ケミカルバイオロジー学会 第7回年会 ,京都(京都大学百周年時計台記念館) 2012/06/07 Refereed Japanese Disclose to all
田中弦 ,中瀬生彦、奥村真也、今西未来、二木史朗 田中弦 ,中瀬生彦、奥村真也、今西未来、二木史朗 細胞外ドメインの置換によるEGF受容体の会合・活性化制御 細胞外ドメインの置換によるEGF受容体の会合・活性化制御 第3回統合物質シンポジウム ,福岡(九州大学西新プラザ) 第3回統合物質シンポジウム ,福岡(九州大学西新プラザ) 2012/06/01 Refereed Japanese Disclose to all
奥彰彦 ,游晧欣、中瀬生彦、二木史朗 奥彰彦 ,游晧欣、中瀬生彦、二木史朗 細胞内安定型ユビキチン多量体の構築のための新しいアプローチ 細胞内安定型ユビキチン多量体の構築のための新しいアプローチ 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/31 Refereed Japanese Disclose to all
川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 フォトクロスリンカーを用いたアルギニンペプチドの取り込みに関与する細胞分子の探索 フォトクロスリンカーを用いたアルギニンペプチドの取り込みに関与する細胞分子の探索 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/30 Refereed Japanese Disclose to all
村山知 ,PUJALS, S?lvia、二木史朗 村山知 ,PUJALS, S?lvia、二木史朗 膜障害性に寄与するAdenovirus internal proteinVI の配列デザインに関する研究 膜障害性に寄与するAdenovirus internal proteinVI の配列デザインに関する研究 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/30 Refereed Japanese Disclose to all
中瀬生彦 ,小西雄介、上田真史、佐治英郎、二木史朗 中瀬生彦 ,小西雄介、上田真史、佐治英郎、二木史朗 In vivoにおける膜透過性ペプチドの腫瘍集積と抗癌剤送達 In vivoにおける膜透過性ペプチドの腫瘍集積と抗癌剤送達 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/29 Refereed Japanese Disclose to all
東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 ジピコリルアミン含有ヘリックスペプチドのNi(II)イオン特異的応答性 ジピコリルアミン含有ヘリックスペプチドのNi(II)イオン特異的応答性 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/29 Refereed Japanese Disclose to all
片山沙綾香 ,中瀬生彦、奥村真也、二木史朗 片山沙綾香 ,中瀬生彦、奥村真也、二木史朗 ミトコンドリアを標的にする膜透過性ペプチドの創製と活性分子送達 ミトコンドリアを標的にする膜透過性ペプチドの創製と活性分子送達 日本薬学会第132回年会 ,札幌(北海道大学) 日本薬学会第132回年会 ,札幌(北海道大学) 2012/03/29 Refereed Japanese Disclose to all
中瀬生彦 ,大崎勝弘、奥村真也、二木史朗 中瀬生彦 ,大崎勝弘、奥村真也、二木史朗 ヘリックス間相互作用で活性化される人工EGF受容体の創製と細胞機能制御 ヘリックス間相互作用で活性化される人工EGF受容体の創製と細胞機能制御 第2回京都大学GCOE-理化学研究所 共同シンポジウム ,京都(京大桂キャンパス) 第2回京都大学GCOE-理化学研究所 共同シンポジウム ,京都(京大桂キャンパス) 2011/11/11 Refereed Japanese Disclose to all
田中弦 ,川口祥正、中瀬生彦、福田保則、畑中保丸、二木史朗 田中弦 ,川口祥正、中瀬生彦、福田保則、畑中保丸、二木史朗 CXCR4はアルギニンペプチド取り込み促進受容体である:光アフィニティーラベル法によるアプローチ CXCR4はアルギニンペプチド取り込み促進受容体である:光アフィニティーラベル法によるアプローチ 第61回日本薬学会近畿支部大会 ,神戸(神戸学院大学) 第61回日本薬学会近畿支部大会 ,神戸(神戸学院大学) 2011/10/22 Refereed Japanese Disclose to all
二木史朗;田中弦;中瀬生彦;福田保則;畑中保丸 二木史朗;田中弦;中瀬生彦;福田保則;畑中保丸 フォトクロスリンク法によるアルギニンペプチド受容体同定の試み フォトクロスリンク法によるアルギニンペプチド受容体同定の試み 反応と合成の進歩シンポジウム講演要旨集, 37th, 44-45 反応と合成の進歩シンポジウム講演要旨集, 37th, 44-45 , 37th, 44-45 2011/10/14 Refereed Japanese Disclose to all
奥彰彦 ,游晧欣、中瀬生彦、二木史朗 奥彰彦 ,游晧欣、中瀬生彦、二木史朗 細胞内安定型ユビキチンダイマー構築のための新しいタンパク質架橋法の開発 細胞内安定型ユビキチンダイマー構築のための新しいタンパク質架橋法の開発 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 2011/09/28 Refereed Japanese Disclose to all
HIROSE Hisaaki;TAKEUCHI Toshihide;NAKASE Ikuhiko;FUTAKI Shiroh HIROSE Hisaaki;TAKEUCHI Toshihide;NAKASE Ikuhiko;FUTAKI Shiroh TOPICAL MIGRATION OF MEMBRANE-ASSOCIATED MOLECULES INDUCED BY DIRECT INFLUX OF ARGININE-RICH PEPTIDES INTO CELLS TOPICAL MIGRATION OF MEMBRANE-ASSOCIATED MOLECULES INDUCED BY DIRECT INFLUX OF ARGININE-RICH PEPTIDES INTO CELLS ペプチド討論会講演要旨集, 48th, 98 ペプチド討論会講演要旨集, 48th, 98 , 48th, 98 2011/09/27 Refereed Japanese Disclose to all
NAKASE Ikuhiko;OSAKI Katsuhiro;OKUMURA Shinya;FUTAKI Shiroh NAKASE Ikuhiko;OSAKI Katsuhiro;OKUMURA Shinya;FUTAKI Shiroh CREATION OF ARTIFICIAL EPIDERMAL GROWTH FACTOR RECEPTOR ACTIVATED BY COILED-COIL PEPTIDES CREATION OF ARTIFICIAL EPIDERMAL GROWTH FACTOR RECEPTOR ACTIVATED BY COILED-COIL PEPTIDES ペプチド討論会講演要旨集, 48th, 116 ペプチド討論会講演要旨集, 48th, 116 , 48th, 116 2011/09/27 Refereed Japanese Disclose to all
川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 川口祥正 ,田中弦、福田保則、中瀬生彦、畑中保丸、二木史朗 フォトクロスリンクを用いたアルギニンリッチペプチドの細胞内移行に関与するタンパク質の探索 フォトクロスリンクを用いたアルギニンリッチペプチドの細胞内移行に関与するタンパク質の探索 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 2011/09/27 Refereed Japanese Disclose to all
能代大輔 ,浅見耕司、二木史朗 能代大輔 ,浅見耕司、二木史朗 ヒスチジン含有アラメチシン誘導体を用いた金属イオンによるリーケージ制御 ヒスチジン含有アラメチシン誘導体を用いた金属イオンによるリーケージ制御 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 第48回ペプチド討論会 ,札幌(札幌コンベンションセンター) 2011/09/27 Refereed Japanese Disclose to all
山本和俊 ,今西未来、二木史朗 山本和俊 ,今西未来、二木史朗 人工時計タンパク質を用いた周期的遺伝子発現システムの構築 人工時計タンパク質を用いた周期的遺伝子発現システムの構築 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 2011/09/13 Refereed Japanese Disclose to all
能代大輔 ,浅見耕司、二木史朗 能代大輔 ,浅見耕司、二木史朗 新規アラメチシン誘導体による金属を用いたリーケージ制御 新規アラメチシン誘導体による金属を用いたリーケージ制御 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 2011/09/13 Refereed Japanese Disclose to all
今西未来;山本和俊;二木史朗 今西未来;山本和俊;二木史朗 人工時計タンパク質によるリズミックな遺伝子発現の誘起 人工時計タンパク質によるリズミックな遺伝子発現の誘起 日本化学会バイオテクノロジー部会シンポジウム講演要旨集, 14th, 69 日本化学会バイオテクノロジー部会シンポジウム講演要旨集, 14th, 69 , 14th, 69 2011/09/12 Refereed Japanese Disclose to all
田中弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 田中弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 膜透過性R12ペプチドの効率的細胞内移行におけるCXCR4の重要性 膜透過性R12ペプチドの効率的細胞内移行におけるCXCR4の重要性 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 第5回バイオ関連化学シンポジウム ,つくば(つくば国際会議場「エポカルつくば」) 2011/09/12 Refereed Japanese Disclose to all
片山沙綾香 ,広瀬久昭、高山健太郎、中瀬生彦、二木史朗 片山沙綾香 ,広瀬久昭、高山健太郎、中瀬生彦、二木史朗 膜透過ペプチドを用いた細胞内への分子送達 膜透過ペプチドを用いた細胞内への分子送達 遺伝子・デリバリー研究会 第11回夏期セミナー ,高知(三翠園ホテル) 遺伝子・デリバリー研究会 第11回夏期セミナー ,高知(三翠園ホテル) 2011/08/08 Refereed Japanese Disclose to all
田中弦 ,中瀬生彦、福田保則、二木史朗 田中弦 ,中瀬生彦、福田保則、二木史朗 膜透過性R12ペプチドの効率的細胞内移行におけるCXCR4の寄与 膜透過性R12ペプチドの効率的細胞内移行におけるCXCR4の寄与 生体機能関連化学部会若手の会 第23回サマースクール ,広島(宮島グランドホテル) 生体機能関連化学部会若手の会 第23回サマースクール ,広島(宮島グランドホテル) 2011/07/22 Refereed Japanese Disclose to all
東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 ジピコリルアミン骨格をもつペプチドによるニッケル(II)の選択的検出 ジピコリルアミン骨格をもつペプチドによるニッケル(II)の選択的検出 第21回金属の関与する生体関連反応シンポジウム ,千葉(千葉大学) 第21回金属の関与する生体関連反応シンポジウム ,千葉(千葉大学) 2011/05/30 Refereed Japanese Disclose to all
田中弦 ,中瀬生彦、福田保則、二木史朗 田中弦 ,中瀬生彦、福田保則、二木史朗 細胞内移行を促進する膜透過性アルギニンペプチド受容体の同定 細胞内移行を促進する膜透過性アルギニンペプチド受容体の同定 統合物質創製化学推進事業第2回若手研究会 ,千歳 統合物質創製化学推進事業第2回若手研究会 ,千歳 2011/05/28 Refereed Japanese Disclose to all
田中弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 田中弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 膜透過性アルギニンペプチドの効率的細胞内移行におけるCXCR4の寄与 膜透過性アルギニンペプチドの効率的細胞内移行におけるCXCR4の寄与 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 2011/05/25 Refereed Japanese Disclose to all
東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 東佑翼 ,今井晴賀、今西未来、吉村智之、川端猛夫、二木史朗 金属イオンによって安定化されるジピコリルアミン骨格含有単鎖へリックス性ペプチドの設計と合成 金属イオンによって安定化されるジピコリルアミン骨格含有単鎖へリックス性ペプチドの設計と合成 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 2011/05/25 Refereed Japanese Disclose to all
能代大輔 ,浅見耕司、二木史朗 能代大輔 ,浅見耕司、二木史朗 Alamethicinをベースにした金属イオン感受性人工イオンチャネルの創製 Alamethicinをベースにした金属イオン感受性人工イオンチャネルの創製 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 日本ケミカルバイオロジー学会第6回年会 ,東京(東京工業大学) 2011/05/24 Refereed Japanese Disclose to all
高山健太郎 ,中瀬生彦、二木史朗 高山健太郎 ,中瀬生彦、二木史朗 膜透過促進配列の付加に伴うアルギニンペプチドの細胞内移行の亢進 膜透過促進配列の付加に伴うアルギニンペプチドの細胞内移行の亢進 第 9 回次世代を担う若手ファーマ・バイオフォーラム2010 ,京都 第 9 回次世代を担う若手ファーマ・バイオフォーラム2010 ,京都 2010/10/02 Refereed Japanese Disclose to all
田中 弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 田中 弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 マクロピノサイトーシスを誘導するR12ペプチド受容体の同定 マクロピノサイトーシスを誘導するR12ペプチド受容体の同定 第4回バイオ関連化学シンポジウム ,豊中(大阪大学豊中キャンパス) 第4回バイオ関連化学シンポジウム ,豊中(大阪大学豊中キャンパス) 2010/09/24 Refereed Japanese Disclose to all
中屋智博 ,今西未来、森崎 達也、能代 大輔、二木史朗、杉浦 幸雄 中屋智博 ,今西未来、森崎 達也、能代 大輔、二木史朗、杉浦 幸雄 Creation of a zinc finger type transcription factor responsive to Zn(II) concentration Creation of a zinc finger type transcription factor responsive to Zn(II) concentration 金属の関与する生体関連反応シンポジウム ,徳島 金属の関与する生体関連反応シンポジウム ,徳島 2010/06/25 Refereed Japanese Disclose to all
中村篤史 ,中村篤史、今西未来、土居雅夫、岡村均、二木史朗 中村篤史 ,中村篤史、今西未来、土居雅夫、岡村均、二木史朗 ゲノムレベルでの時計遺伝子プロモーター解析を目指した亜鉛フィンガー型人工転写因子の創製とその機能 ゲノムレベルでの時計遺伝子プロモーター解析を目指した亜鉛フィンガー型人工転写因子の創製とその機能 日本ケミカルバイオロジー学会第5年会 ,横浜(慶応義塾大学日吉キャンパス) 日本ケミカルバイオロジー学会第5年会 ,横浜(慶応義塾大学日吉キャンパス) 2010/05/19 Refereed Japanese Disclose to all
田中 弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 田中 弦 ,中瀬生彦、福田保則、畑中保丸、二木史朗 アルギニンペプチドによるマクロピノサイトーシス誘導受容体の同定 アルギニンペプチドによるマクロピノサイトーシス誘導受容体の同定 日本ケミカルバイオロジー学会 第5回年会 ,横浜(慶応義塾大学日吉キャンパス) 日本ケミカルバイオロジー学会 第5回年会 ,横浜(慶応義塾大学日吉キャンパス) 2010/05/19 Refereed Japanese Disclose to all
中屋智博 ,森崎 達也、能代 大輔、今西未来、二木史朗、杉浦 幸雄 中屋智博 ,森崎 達也、能代 大輔、今西未来、二木史朗、杉浦 幸雄 亜鉛濃度に依存した新規転写調節系の開発 亜鉛濃度に依存した新規転写調節系の開発 日本ケミカルバイオロジー学会 第5回 年会 ,横浜 日本ケミカルバイオロジー学会 第5回 年会 ,横浜 2010/05/18 Refereed Japanese Disclose to all
高山健太郎 ,中瀬生彦、二木史朗 高山健太郎 ,中瀬生彦、二木史朗 膜透過促進配列 (Pas) の付加によるアルギニンペプチドの効率的な細胞内移行 膜透過促進配列 (Pas) の付加によるアルギニンペプチドの効率的な細胞内移行 第31回生体膜と薬物の相互作用シンポジウム ,大阪 第31回生体膜と薬物の相互作用シンポジウム ,大阪 2009/12/01 Refereed Japanese Disclose to all
A. Nishio; N. Sawa; K. Onodera; S. Sakamoto; Y. Araki; I. Nakase; S. Futaki; Y. Inoue; T. Wada Akihiro Nishio, Nobuya Sawa, Keiko Onodera, Seiji Sakamoto, Yasuyuki Araki, Ikuhiko Nakase, Shiroh Futaki, Yoshihisa Inoue, Takehiko Wada A. Nishio; N. Sawa; K. Onodera; S. Sakamoto; Y. Araki; I. Nakase; S. Futaki; Y. Inoue; T. Wada Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA. Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA. Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA. Nucleic acids symposium series (2004), 53, 55-56 Nucleic acids symposium series (2004), 53, 55-56 Nucleic acids symposium series (2004), 53, 55-56 2009/12/01 English Disclose to all
二木史朗 ,高山健太郎、中瀬生彦 二木史朗 ,高山健太郎、中瀬生彦 膜透過ペプチドを用いた癌増殖抑制ペプチドの細胞内導入 膜透過ペプチドを用いた癌増殖抑制ペプチドの細胞内導入 第28回メディシナルケミストリーシンポジウム ,東京 第28回メディシナルケミストリーシンポジウム ,東京 2009/11/25 Refereed Japanese Disclose to all
二木史朗 ,東佑翼、今西未来、吉村智之、川端猛夫 二木史朗 ,東佑翼、今西未来、吉村智之、川端猛夫 ロイシンジッパー型タンパク質への金属配位子の位置選択的導入とDNA結合スイッチ ロイシンジッパー型タンパク質への金属配位子の位置選択的導入とDNA結合スイッチ 第35回反応と合成の進歩シンポジウム ,金沢 第35回反応と合成の進歩シンポジウム ,金沢 2009/11/16 Refereed Japanese Disclose to all
二木史朗 ,野口晴加、能代大輔、浅見耕司 二木史朗 ,野口晴加、能代大輔、浅見耕司 アラメチシンのアミノ酸置換とチャネル活性 アラメチシンのアミノ酸置換とチャネル活性 第46回ペプチド討論会 ,北九州 第46回ペプチド討論会 ,北九州 2009/11/05 Refereed Japanese Disclose to all
游 晧欣 ,中瀬 生彦、Silvia Pujals、今西未来、二木史朗 游 晧欣 ,中瀬 生彦、Silvia Pujals、今西未来、二木史朗 Expressed Protein Ligation法を用いた膜透過性アルギニンペプチド結合タンパク質の調製と細胞内導入 Expressed Protein Ligation法を用いた膜透過性アルギニンペプチド結合タンパク質の調製と細胞内導入 第46回ペプチド討論会 ,北九州 第46回ペプチド討論会 ,北九州 2009/11/05 Refereed Japanese Disclose to all
中村篤史 ,中村篤史、今西未来、土居雅夫、岡村均、二木史朗 中村篤史 ,中村篤史、今西未来、土居雅夫、岡村均、二木史朗 時計遺伝子プロモーター解析へ向けた亜鉛フィンガー型人工転写因子の創製 時計遺伝子プロモーター解析へ向けた亜鉛フィンガー型人工転写因子の創製 第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会. 2009 合同大会 ,大阪 第6回アジア睡眠学会 日本睡眠学会第34回定期学術集会 第16回日本時間生物学会学術大会. 2009 合同大会 ,大阪 2009/10/27 Refereed Japanese Disclose to all
広瀬久昭 ,田中 弦、中瀬生彦、二木史朗 広瀬久昭 ,田中 弦、中瀬生彦、二木史朗 細胞膜を透過するアルギニンペプチドの細胞内拡散経路に関する検討 細胞膜を透過するアルギニンペプチドの細胞内拡散経路に関する検討 第82回日本生化学会 ,神戸 第82回日本生化学会 ,神戸 2009/10/23 Refereed Japanese Disclose to all
東 佑翼 ,今西未来 、吉村 智之 、川端 猛夫 、二木史朗 東 佑翼 ,今西未来 、吉村 智之 、川端 猛夫 、二木史朗 金属錯形成部位のペプチドへの効率的導入法の開発 金属錯形成部位のペプチドへの効率的導入法の開発 第24回生体機能関連化学シンポジウム,第12回バイオテクノロジー部会シンポジウム ,福岡 第24回生体機能関連化学シンポジウム,第12回バイオテクノロジー部会シンポジウム ,福岡 2009/09/14 Refereed Japanese Disclose to all
小出隆規(早大理工) ,遠藤裕之、中瀬生彦、二木史朗 小出隆規(早大理工) ,遠藤裕之、中瀬生彦、二木史朗 細胞内に移行するコラーゲン様ペプチドのデザイン 細胞内に移行するコラーゲン様ペプチドのデザイン 第3回関東支部大会 ,東京 第3回関東支部大会 ,東京 2009/09/05 Refereed Japanese Disclose to all
今西未来 ,今西未来、中村篤史、二木史朗 今西未来 ,今西未来、中村篤史、二木史朗 Creation of artificial zinc finger-type transcription factors and effects on the rhythmic expression of clock genes Creation of artificial zinc finger-type transcription factors and effects on the rhythmic expression of clock genes 第19回金属の関与する生体関連シンポジウム(SRM 2009) ,吹田(大阪大学) 第19回金属の関与する生体関連シンポジウム(SRM 2009) ,吹田(大阪大学) 2009/06/12 Refereed Japanese Disclose to all
今西未来 ,今西未来、中村篤史、二木史朗 今西未来 ,今西未来、中村篤史、二木史朗 シスエレメントを標的とした人工ジンクフィンガー連結体のDNA結合性の解析 シスエレメントを標的とした人工ジンクフィンガー連結体のDNA結合性の解析 第9回日本蛋白質科学会年会 ,熊本(熊本全日空ホテルニュースカイ) 第9回日本蛋白質科学会年会 ,熊本(熊本全日空ホテルニュースカイ) 2009/05/22 Refereed Japanese Disclose to all
森崎達也 ,森崎達也、今西未来、二木史朗、杉浦幸雄 森崎達也 ,森崎達也、今西未来、二木史朗、杉浦幸雄 細胞内におけるマルチ亜鉛フィンガータンパク質のDNA結合特性 細胞内におけるマルチ亜鉛フィンガータンパク質のDNA結合特性 第9回日本蛋白質科学会年会 ,熊本(熊本全日空ホテルニュースカイ) 第9回日本蛋白質科学会年会 ,熊本(熊本全日空ホテルニュースカイ) 2009/05/22 Refereed Japanese Disclose to all
AZUMA Yusuke;IMANISHI Miki;YOSHIMURA Tomoyuki;KAWABATA Takeo;FUTAKI Shiroh AZUMA Yusuke;IMANISHI Miki;YOSHIMURA Tomoyuki;KAWABATA Takeo;FUTAKI Shiroh Metal-induced DNA-binding switch of bZIP proteins modified with iminodiacetic acid (Ida) Metal-induced DNA-binding switch of bZIP proteins modified with iminodiacetic acid (Ida) 金属の関与する生体関連反応シンポジウム講演要旨集, 19th, 66 金属の関与する生体関連反応シンポジウム講演要旨集, 19th, 66 , 19th, 66 2009/05/20 Refereed Japanese Disclose to all
福田保則 ,畑中保丸、二木史朗 福田保則 ,畑中保丸、二木史朗 光架橋による細胞内ペプチドータンパク質相互作用の解析 光架橋による細胞内ペプチドータンパク質相互作用の解析 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 2008/12/11 Refereed Japanese Disclose to all
広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 効率的に細胞内移行するアルギニンペプチドとその経路 効率的に細胞内移行するアルギニンペプチドとその経路 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 2008/12/09 Refereed Japanese Disclose to all
森崎達也 ,今西未来、二木史朗、杉浦幸雄 森崎達也 ,今西未来、二木史朗、杉浦幸雄 マルチ亜鉛フィンガーのin vitro及びin celluloでの挙動相関 マルチ亜鉛フィンガーのin vitro及びin celluloでの挙動相関 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会 ,神戸 2008/12/09 Refereed Japanese Disclose to all
T. Wada; N. Sawa; H. Sato; S. Futaki; Y. Inoue Takehiko Wada, Nobuya Sawa, Hirofumi Sato, Shiroh Futaki, Yoshihisa Inoue T. Wada; N. Sawa; H. Sato; S. Futaki; Y. Inoue Effects of arginine residue introduction upon interaction and complexation behavior of peptide ribonucleic acids (PRNAs) with RNA: synthesis and properties of alpha-containing arginine. Effects of arginine residue introduction upon interaction and complexation behavior of peptide ribonucleic acids (PRNAs) with RNA: synthesis and properties of alpha-containing arginine. Effects of arginine residue introduction upon interaction and complexation behavior of peptide ribonucleic acids (PRNAs) with RNA: synthesis and properties of alpha-containing arginine. Nucleic acids symposium series (2004), 52, 673-674 Nucleic acids symposium series (2004), 52, 673-674 Nucleic acids symposium series (2004), 52, 673-674 2008/12/01 English Disclose to all
湯川 博 ,野口洋文、中瀬生彦、宮本義孝、大石幸一、二木史朗、林衆治 湯川 博 ,野口洋文、中瀬生彦、宮本義孝、大石幸一、二木史朗、林衆治 iPS細胞に対する蛋白導入ドメインの有効性比較 iPS細胞に対する蛋白導入ドメインの有効性比較 第35回日本臓器保存生物医学会総会 ,東京 第35回日本臓器保存生物医学会総会 ,東京 2008/11/22 Refereed Japanese Disclose to all
片山沙綾香 ,広瀬久昭、二木史朗 片山沙綾香 ,広瀬久昭、二木史朗 Enhanced cell internalization of octaarginine by fatty acid modification Enhanced cell internalization of octaarginine by fatty acid modification 第45回 ペプチド討論会The 45th Japanese Peptide Symposium ,東京 第45回 ペプチド討論会The 45th Japanese Peptide Symposium ,東京 2008/10/30 Refereed Japanese Disclose to all
NAKASE Ikuhiko;HIROSE Hisaaki;FUTAKI Shiroh NAKASE Ikuhiko;HIROSE Hisaaki;FUTAKI Shiroh EFFICIENT CELLULAR UPTAKE OF FLOCK HOUSE VIRUS DERIVED PEPTIDE EFFICIENT CELLULAR UPTAKE OF FLOCK HOUSE VIRUS DERIVED PEPTIDE ペプチド討論会講演要旨集, 45th, 53 ペプチド討論会講演要旨集, 45th, 53 , 45th, 53 2008/10/14 Refereed Japanese Disclose to all
中瀬生彦 , 中瀬生彦 , アルギニンペプチドの効率的マクロピノサイトーシス誘導と細胞内移行 アルギニンペプチドの効率的マクロピノサイトーシス誘導と細胞内移行 インテックセンター生体医工学研究部門講演会・グローバルCOE化学系バイオ若手バイオシンポジウム ,京都 インテックセンター生体医工学研究部門講演会・グローバルCOE化学系バイオ若手バイオシンポジウム ,京都 2008/09/29 Refereed Japanese Disclose to all
東 佑翼 ,吉村 智之、川端 猛夫、二木史朗 東 佑翼 ,吉村 智之、川端 猛夫、二木史朗 Ida修飾化システインを用いた金属応答性bZIPペプチドの創製とDNA結合スイッチ Ida修飾化システインを用いた金属応答性bZIPペプチドの創製とDNA結合スイッチ 第3回バイオ関連化学合同シンポジウム ,横浜 第3回バイオ関連化学合同シンポジウム ,横浜 2008/09/19 Refereed Japanese Disclose to all
今西未来;今西未来;中村篤史;二木史朗 今西未来;今西未来;中村篤史;二木史朗 時計遺伝子プロモーターに作用するジンクフィンガー型人工転写因子の創製 時計遺伝子プロモーターに作用するジンクフィンガー型人工転写因子の創製 日本化学会バイオテクノロジー部会シンポジウム講演要旨集, 11th, 234 日本化学会バイオテクノロジー部会シンポジウム講演要旨集, 11th, 234 , 11th, 234 2008/09/08 Refereed Japanese Disclose to all
中瀬生彦 ,広瀬久昭、二木史朗 中瀬生彦 ,広瀬久昭、二木史朗 FHVペプチドの効率的な膜透過機能 FHVペプチドの効率的な膜透過機能 第30回生体膜と薬物の相互作用シンポジウム ,札幌 第30回生体膜と薬物の相互作用シンポジウム ,札幌 2008/08/08 Refereed Japanese Disclose to all
東 佑翼 ,吉村 智之、川端 猛夫、二木史朗 東 佑翼 ,吉村 智之、川端 猛夫、二木史朗 Ida-Co(II)錯形成を利用した人工金属応答性ロイシンジッパーの構造スイッチ Ida-Co(II)錯形成を利用した人工金属応答性ロイシンジッパーの構造スイッチ 第18回金属の関与する生体関連反応シンポジウム(SRM2008) ,名古屋 第18回金属の関与する生体関連反応シンポジウム(SRM2008) ,名古屋 2008/06/05 Refereed Japanese Disclose to all
能代大輔 ,浅見耕司、二木史朗 能代大輔 ,浅見耕司、二木史朗 金属イオンによる会合制御が可能なチャネル形成ペプチドの創製とその応用 金属イオンによる会合制御が可能なチャネル形成ペプチドの創製とその応用 第18回金属の関与する生体関連反応シンポジウム(SRM2008) ,名古屋 第18回金属の関与する生体関連反応シンポジウム(SRM2008) ,名古屋 2008/06/05 Refereed Japanese Disclose to all
中村保則 ,兼田真樹、武内敏秀、畑中保丸、二木史朗 中村保則 ,兼田真樹、武内敏秀、畑中保丸、二木史朗 膜透過ペプチドを用いた細胞内タンパク質相互作用解析 膜透過ペプチドを用いた細胞内タンパク質相互作用解析 ケミカルバイオロジー研究会年会 ,東京 ケミカルバイオロジー研究会年会 ,東京 2008/05/20 Refereed Japanese Disclose to all
森崎達也 ,今西未来、二木史朗、杉浦幸雄 森崎達也 ,今西未来、二木史朗、杉浦幸雄 マルチ亜鉛フィンガー型人工転写因子による経時的転写活性化能の解析 マルチ亜鉛フィンガー型人工転写因子による経時的転写活性化能の解析 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 2007/12/12 Refereed Japanese Disclose to all
安岡寛子 ,辻 大輔、広瀬由記子、明星裕美、千葉靖典、地神芳文、二木史郎、桜庭 均、伊藤孝司 安岡寛子 ,辻 大輔、広瀬由記子、明星裕美、千葉靖典、地神芳文、二木史郎、桜庭 均、伊藤孝司 Cell penetrating peptideを用いたヒトβ-ヘキソサミニダーゼの細胞内補充効果の検討 Cell penetrating peptideを用いたヒトβ-ヘキソサミニダーゼの細胞内補充効果の検討 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 2007/12/11 Refereed Japanese Disclose to all
広瀬 由記子 ,広瀬由記子、辻 大輔、安岡寛子、二木史郎、伊藤孝司 広瀬 由記子 ,広瀬由記子、辻 大輔、安岡寛子、二木史郎、伊藤孝司 オリゴアルギニンペプチド融合タンパクの細胞内局在解析 オリゴアルギニンペプチド融合タンパクの細胞内局在解析 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 第30回日本分子生物学会年会・第80回日本生化学回大会合同大会 ,横浜 2007/12/11 Refereed Japanese Disclose to all
二木史朗 ,武内敏秀、小管通江、中瀬生彦 二木史朗 ,武内敏秀、小管通江、中瀬生彦 Effect of Peptide Concentration and Serum on the Modes of Internalization of Arginine-rich Peptides Effect of Peptide Concentration and Serum on the Modes of Internalization of Arginine-rich Peptides 第29回生体膜と薬物の相互作用シンポジウム ,仙台 第29回生体膜と薬物の相互作用シンポジウム ,仙台 2007/11/26 Refereed Japanese Disclose to all
中瀬生彦 , 中瀬生彦 , 膜透過性アルギニンペプチドの効率的な細胞内移行 膜透過性アルギニンペプチドの効率的な細胞内移行 平成19年度ペプチド若手の集い(第44回 ペプチド討論会) ,富山 平成19年度ペプチド若手の集い(第44回 ペプチド討論会) ,富山 2007/11/17 Refereed Japanese Disclose to all
広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 フロックハウスウイルス由来ペプチドの効率的細胞内移行 フロックハウスウイルス由来ペプチドの効率的細胞内移行 第44回ペプチド討論会 ,富山 第44回ペプチド討論会 ,富山 2007/11/08 Refereed Japanese Disclose to all
東 佑翼 ,吉村智之、川端 猛夫、二木史朗 東 佑翼 ,吉村智之、川端 猛夫、二木史朗 修飾システインを用いた金属応答性ペプチドの開発 修飾システインを用いた金属応答性ペプチドの開発 第44回ペプチド討論会 ,富山 第44回ペプチド討論会 ,富山 2007/11/08 Refereed Japanese Disclose to all
広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 広瀬久昭 ,武内敏秀、中瀬生彦、二木史朗 高効率に細胞内移行するFHVペプチドの機能評価 高効率に細胞内移行するFHVペプチドの機能評価 第57回日本薬学会近畿支部大会 ,高槻 第57回日本薬学会近畿支部大会 ,高槻 2007/10/27 Refereed Japanese Disclose to all
小林祥子 ,川畑紀子、中瀬生彦、二木史朗 小林祥子 ,川畑紀子、中瀬生彦、二木史朗 カチオン性脂質とpH感受性ペプチドによるタンパク質の効率的細胞内導入 カチオン性脂質とpH感受性ペプチドによるタンパク質の効率的細胞内導入 第57回日本薬学会近畿支部大会 ,高槻 第57回日本薬学会近畿支部大会 ,高槻 2007/10/27 Refereed Japanese Disclose to all
中村篤史 ,今西未来、二木史朗 中村篤史 ,今西未来、二木史朗 プロモーターを標的とする人工マルチ亜鉛フィンガータンパク質の創製:モチーフの連結によるDNA結合性への影響 プロモーターを標的とする人工マルチ亜鉛フィンガータンパク質の創製:モチーフの連結によるDNA結合性への影響 第57回日本薬学会近畿支部大会 ,高槻 第57回日本薬学会近畿支部大会 ,高槻 2007/10/27 Refereed Japanese Disclose to all
能代大輔 ,浅見孝司、二木史朗 能代大輔 ,浅見孝司、二木史朗 キレート形成原子団導入によるアラメチシンの会合安定化 キレート形成原子団導入によるアラメチシンの会合安定化 第57回日本薬学会近畿支部大会 ,高槻 第57回日本薬学会近畿支部大会 ,高槻 2007/10/27 Refereed Japanese Disclose to all
NAKAMURA Yasunori;KANEDA Masaki;TAKEUCHI Toshihide;HATANAKA Yasumaru;FUTAKI Shiroh NAKAMURA Yasunori;KANEDA Masaki;TAKEUCHI Toshihide;HATANAKA Yasumaru;FUTAKI Shiroh DESIGN OF PHOSPHOPEPTIDES BEARING PHOTO-CROSS-LINKER FOR THE ANALYSIS OF IN-CELL PROTEIN RECOGNITION DESIGN OF PHOSPHOPEPTIDES BEARING PHOTO-CROSS-LINKER FOR THE ANALYSIS OF IN-CELL PROTEIN RECOGNITION ペプチド討論会講演要旨集, 44th, 133 ペプチド討論会講演要旨集, 44th, 133 , 44th, 133 2007/10/15 Refereed Japanese Disclose to all
小林祥子 ,川畑紀子、中瀬生彦、二木史朗 小林祥子 ,川畑紀子、中瀬生彦、二木史朗 カチオン性脂質共存下におけるpH感受性ペプチドの細胞内移行促進 カチオン性脂質共存下におけるpH感受性ペプチドの細胞内移行促進 第22回生体機能関連化学シンポジウム ,仙台 第22回生体機能関連化学シンポジウム ,仙台 2007/09/28 Refereed Japanese Disclose to all
二木史朗 ,武内敏秀、小管通江、中瀬生彦 二木史朗 ,武内敏秀、小管通江、中瀬生彦 アルギニンペプチドの細胞移行機序の濃度依存性 アルギニンペプチドの細胞移行機序の濃度依存性 第22回生体機能関連化学シンポジウム ,仙台 第22回生体機能関連化学シンポジウム ,仙台 2007/09/28 Refereed Japanese Disclose to all
能代大輔 ,浅見孝司、二木史朗 能代大輔 ,浅見孝司、二木史朗 金属イオンによるチャネル形成ペプチドの会合安定化 Metal-mediated stabilization of channel peptide assemblies 金属イオンによるチャネル形成ペプチドの会合安定化 Metal-mediated stabilization of channel peptide assemblies 第22回生体機能関連化学シンポジウム ,仙台 第22回生体機能関連化学シンポジウム ,仙台 2007/09/28 Refereed Japanese Disclose to all
今西未来 , 今西未来 , 遺伝子制御に向けたマルチ亜鉛フィンガータンパク質の創製 遺伝子制御に向けたマルチ亜鉛フィンガータンパク質の創製 第20回バイオメディカル分析科学シンポジウム ,八王子 第20回バイオメディカル分析科学シンポジウム ,八王子 2007/07/02 Refereed Japanese Disclose to all
IMANISHI Miki;YAN Wei;FUTAKI Shiroh;SUGIURA Yukio IMANISHI Miki;YAN Wei;FUTAKI Shiroh;SUGIURA Yukio Linker design of multiple zinc finger peptides: flexible, polycationic, and metal-binding looped linkers Linker design of multiple zinc finger peptides: flexible, polycationic, and metal-binding looped linkers 金属の関与する生体関連反応シンポジウム講演要旨集, 17th, 69 金属の関与する生体関連反応シンポジウム講演要旨集, 17th, 69 , 17th, 69 2007/06/01 Refereed Japanese Disclose to all
中瀬生彦 ,田所明子、武内敏秀、二木史朗 中瀬生彦 ,田所明子、武内敏秀、二木史朗 膜透過性アルギニンペプチド:細胞による効率的な取り込みとプロテオグリカン依存性 膜透過性アルギニンペプチド:細胞による効率的な取り込みとプロテオグリカン依存性 日本ケミカルバイオロジー研究会 第2回年会 ,京都 日本ケミカルバイオロジー研究会 第2回年会 ,京都 2007/05/10 Refereed Japanese Disclose to all
能代大輔 ,園田和弘、東野俊介、浅見孝司、二木史朗 能代大輔 ,園田和弘、東野俊介、浅見孝司、二木史朗 金属を認識する人工受容体型チャネルタンパク質の設計 Designing Artificial Metal-gated Ion Channels 金属を認識する人工受容体型チャネルタンパク質の設計 Designing Artificial Metal-gated Ion Channels 日本ケミカルバイオロジー研究会 第2回年会 ,京都 日本ケミカルバイオロジー研究会 第2回年会 ,京都 2007/05/10 Refereed Japanese Disclose to all
閻 薇 ,今西未来、二木史朗、杉浦幸雄 閻 薇 ,今西未来、二木史朗、杉浦幸雄 aヘリックスリンカーが人工6-亜鉛フィンガーペプチドのDNA 結合に及ぼす影響 aヘリックスリンカーが人工6-亜鉛フィンガーペプチドのDNA 結合に及ぼす影響 日本ケミカルバイオロジー研究会 第2回年会 ,京都 日本ケミカルバイオロジー研究会 第2回年会 ,京都 2007/05/10 Refereed Japanese Disclose to all
中村篤史 ,今西未来、二木史朗 中村篤史 ,今西未来、二木史朗 Creation of artificial zinc finger type transcription factors Creation of artificial zinc finger type transcription factors 日本ケミカルバイオロジー研究会 第2回年会 ,京都 日本ケミカルバイオロジー研究会 第2回年会 ,京都 2007/05/09 Refereed Japanese Disclose to all
T. Wada; Y. Maeda; N. Sawa; H. Sato; S. Futaki; Y. Inoue Takehiko Wada, Yoshiki Maeda, Nobuya Sawa, Hirofumi Sato, Shiroh Futaki, Yoshihisa Inoue T. Wada; Y. Maeda; N. Sawa; H. Sato; S. Futaki; Y. Inoue RNA recognition and recognition control of alpha-peptide ribonucleic acids containing arginine residue by external factors. RNA recognition and recognition control of alpha-peptide ribonucleic acids containing arginine residue by external factors. RNA recognition and recognition control of alpha-peptide ribonucleic acids containing arginine residue by external factors. Nucleic acids symposium series (2004), 50, 75-76 Nucleic acids symposium series (2004), 50, 75-76 Nucleic acids symposium series (2004), 50, 75-76 2006/12/01 English Disclose to all
二木史朗 , 二木史朗 , 膜透過ペプチドを用いた細胞内デリバリー 膜透過ペプチドを用いた細胞内デリバリー 徳島大学大学院ヘルスバイオサイエンス研究部講義 ,徳島 徳島大学大学院ヘルスバイオサイエンス研究部講義 ,徳島 2006/06/02 Refereed Japanese Disclose to all
Y. Hori; K. Suzuki; Y. Okuno; M. Nagaoka; S. Futaki; Y. Sugiura Y. Hori, K. Suzuki, Y. Okuno, M. Nagaoka, S. Futaki, Y. Sugiura Y. Hori; K. Suzuki; Y. Okuno; M. Nagaoka; S. Futaki; Y. Sugiura The engineering, structure, and DNA binding properties of a novel His4-type zinc finger peptide. The engineering, structure, and DNA binding properties of a novel His4-type zinc finger peptide. The engineering, structure, and DNA binding properties of a novel His4-type zinc finger peptide. Nucleic acids symposium series, 44, 295-296 Nucleic acids symposium series, 44, 295-296 Nucleic acids symposium series, 44, 295-296 2000/01/01 English Disclose to all
R. Tachibana; H. Harashima; S. Futaki; M. Shono; H. Kiwada R. Tachibana, H. Harashima, S. Futaki, M. Shono, H. Kiwada R. Tachibana; H. Harashima; S. Futaki; M. Shono; H. Kiwada Control of intracellular disposition of liposomally encapsulated FITC-albumin in macrophages Control of intracellular disposition of liposomally encapsulated FITC-albumin in macrophages Control of intracellular disposition of liposomally encapsulated FITC-albumin in macrophages Proceedings of the Controlled Release Society, 24, 791-792 Proceedings of the Controlled Release Society, 24, 791-792 Proceedings of the Controlled Release Society, 24, 791-792 1997/01/01 English Disclose to all
Tanaka, G. ,Nakase, I.; Okumura, S.; Osaki, K.; Futaki, S. Tanaka, G. ,Nakase, I.; Okumura, S.; Osaki, K.; Futaki, S. Creation of Artificial Epidermal Growth Factor Receptor Activated by Bivalent Leucine-zipper Ligand Creation of Artificial Epidermal Growth Factor Receptor Activated by Bivalent Leucine-zipper Ligand 第2回統合物質国際シンポジウム(2012) ,名古屋(名古屋大学) 第2回統合物質国際シンポジウム(2012) ,名古屋(名古屋大学) 2012/12/10 Refereed English Disclose to all
TSUJI, S. ,Imanishi, M.; Futaki, S. TSUJI, S. ,Imanishi, M.; Futaki, S. 5'-Tthymine recognition by TAL effectors. 5'-Tthymine recognition by TAL effectors. The 39th Inernational Symposium on Nucleic Acids Chemistry ,Toyoda Auditorium, Nagoya University The 39th Inernational Symposium on Nucleic Acids Chemistry ,Toyoda Auditorium, Nagoya University 2012/11/16 Refereed English Disclose to all
Imanishi, M. ,Nakamura, A.; Doi, M.; Futaki, S.; Okamura, H. Imanishi, M. ,Nakamura, A.; Doi, M.; Futaki, S.; Okamura, H. Resetting the Cellular Circadian Clock by an Artificial Zinc-finger Transcription Factor Resetting the Cellular Circadian Clock by an Artificial Zinc-finger Transcription Factor FASEB SCIENCE RESEARCH CONFERENCES Genome Engineering: Research & Applications" ,Lucca, Italy FASEB SCIENCE RESEARCH CONFERENCES Genome Engineering: Research & Applications" ,Lucca, Italy 2012/09/05 Refereed English Disclose to all
Imanishi, M. ,Nakamura, A.; Doi, M.; Okamura, H.; Futaki, S. Imanishi, M. ,Nakamura, A.; Doi, M.; Okamura, H.; Futaki, S. Resetting of the cellular circadian clock by an artificial zinc-finger transcription factor Resetting of the cellular circadian clock by an artificial zinc-finger transcription factor 金属の関与する生体関連反応シンポジウム(SRM2012) ,金沢(金沢大学) 金属の関与する生体関連反応シンポジウム(SRM2012) ,金沢(金沢大学) 2012/05/31 Refereed English Disclose to all
NOSHIRO, Daisuke. ,SONOMURA, Kazuhiro,; Yu H.H,; IMANISHI, Miki,; ASAMI, Kouji,; FUTAKI, Shiroh. NOSHIRO, Daisuke. ,SONOMURA, Kazuhiro,; Yu H.H,; IMANISHI, Miki,; ASAMI, Kouji,; FUTAKI, Shiroh. Design and Creation of a Ca2+-sensitive Artificial Channel Protein Design and Creation of a Ca2+-sensitive Artificial Channel Protein International Symposium on Innovative Nanobiodevices ISIN 2012 ,Nagoya, Japan International Symposium on Innovative Nanobiodevices ISIN 2012 ,Nagoya, Japan 2012/03/21 Refereed English Disclose to all
FUTAKI, Shiroh. ,TANAKA, Gen.; NAKASE, Ikuhiko.; FUKUDA, Yasunori.; MASUDA, Ryo.; OISHI, Shinya.; FUJII, Nobutaka.; HATANAKA, Yasumaru. FUTAKI, Shiroh. ,TANAKA, Gen.; NAKASE, Ikuhiko.; FUKUDA, Yasunori.; MASUDA, Ryo.; OISHI, Shinya.; FUJII, Nobutaka.; HATANAKA, Yasumaru. A photocross-link approach to identify receptors that stimulate internalization of oligoarginine peptides A photocross-link approach to identify receptors that stimulate internalization of oligoarginine peptides 8th AFMC International Medicinal Chemistry Symposium “Frontier of Medicinal Science” ,Keio Plaza Hotel Tokyo 8th AFMC International Medicinal Chemistry Symposium “Frontier of Medicinal Science” ,Keio Plaza Hotel Tokyo 2011/12/01 Refereed English Disclose to all
YAMAMOTO, Kazatoshi ,IMANISHI, Miki.; HIROSE, Yuka.; OKAMURA, Hitoshi.; FUTAKI、Shiroh. YAMAMOTO, Kazatoshi ,IMANISHI, Miki.; HIROSE, Yuka.; OKAMURA, Hitoshi.; FUTAKI、Shiroh. Circadian Rhythmic Gene Expression Induced by Artificial Clock Proteins Circadian Rhythmic Gene Expression Induced by Artificial Clock Proteins The 38th International Symposium on Nucleic Acid Chemistry ,Clark Memorial Student Center, Hokkaido University The 38th International Symposium on Nucleic Acid Chemistry ,Clark Memorial Student Center, Hokkaido University 2011/11/10 Refereed English Disclose to all
NAKASE Ikuhiko;KONISHI Yusuke;UEDA Masashi;SAJI Hideo;FUTAKI Shiroh NAKASE Ikuhiko;KONISHI Yusuke;UEDA Masashi;SAJI Hideo;FUTAKI Shiroh IN VIVO TUMOR ACCUMULATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES AND ANTICANCER DRUG DELIVERY IN VIVO TUMOR ACCUMULATION OF ARGININE-RICH CELL-PENETRATING PEPTIDES AND ANTICANCER DRUG DELIVERY ペプチド討論会講演要旨集, 48th, 30 , 48th, 30 ペプチド討論会講演要旨集, 48th, 30 2011/09/27 Refereed English Disclose to all
PUJALS Silvia;TANIUCHI Kentaroh;MIYAMAE Hiroki;UMEDA Masato;FUTAKI Shiroh PUJALS Silvia;TANIUCHI Kentaroh;MIYAMAE Hiroki;UMEDA Masato;FUTAKI Shiroh ELUCIDATING THE EFFECT OF EPSIN DERIVED AMPHIPATHIC PEPTIDE ON CELL-MEMBRANE ARCHITECTURE ELUCIDATING THE EFFECT OF EPSIN DERIVED AMPHIPATHIC PEPTIDE ON CELL-MEMBRANE ARCHITECTURE ペプチド討論会講演要旨集, 48th, 80 , 48th, 80 ペプチド討論会講演要旨集, 48th, 80 2011/09/27 Refereed English Disclose to all
AZUMA, Yusuke. ,IMAI, Haruka.; IMANISHI, Miki.; YOSHIMURA, Tomoyuki.; KABABATA, Takeo.; FUTAKI, Shiroh. AZUMA, Yusuke. ,IMAI, Haruka.; IMANISHI, Miki.; YOSHIMURA, Tomoyuki.; KABABATA, Takeo.; FUTAKI, Shiroh. Bidirectional control of the helical structure of a Dpa-containing peptide using divalent metal ions Bidirectional control of the helical structure of a Dpa-containing peptide using divalent metal ions 22nd American Peptide Symposium ,Sheraton Hotel or Marina, San Diego, California 22nd American Peptide Symposium ,Sheraton Hotel or Marina, San Diego, California 2011/06/25 Refereed English Disclose to all
NOSHIRO, Daisuke. ,ASAMI, Kouji.; FUTAKI, Shiroh. NOSHIRO, Daisuke. ,ASAMI, Kouji.; FUTAKI, Shiroh. Creation of Metal Sensitive Artificial Ion Channels Creation of Metal Sensitive Artificial Ion Channels 22nd American Peptide Symposium ,San Diego, CA, USA 22nd American Peptide Symposium ,San Diego, CA, USA 2011/06/25 Refereed English Disclose to all
Hisaaki HIROSE ,Toshihide TAKEUCHI, Ikuhiko NAKASE, Shiroh FUTAKI Hisaaki HIROSE ,Toshihide TAKEUCHI, Ikuhiko NAKASE, Shiroh FUTAKI Dynamics of membrane-associated molecules that accompany direct penetration of arginine-rich peptides into cells Dynamics of membrane-associated molecules that accompany direct penetration of arginine-rich peptides into cells The 27th Naito Conference (Membrane Dynamics and Lipid Biology [I]) ,Ch?terais? Gateaux Kingdom SAPPORO The 27th Naito Conference (Membrane Dynamics and Lipid Biology [I]) ,Ch?terais? Gateaux Kingdom SAPPORO 2010/06/30 Refereed English Disclose to all
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Design and Creation of the GCN4-bZIP Proteins Functionalized with Iminodiacetic Acid for On/Off Switch of the DNA Binding by Metal Ions Design and Creation of the GCN4-bZIP Proteins Functionalized with Iminodiacetic Acid for On/Off Switch of the DNA Binding by Metal Ions Gordon Research Conference on Bioorganic Chemistry ,Proctor Academy (Andover, NH) Gordon Research Conference on Bioorganic Chemistry ,Proctor Academy (Andover, NH) 2010/06/13 Refereed English Disclose to all
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Functionalization of GCN4-bZIP with iminodiacetic acid that allow the DNA binding to be controlled by a metal ion Functionalization of GCN4-bZIP with iminodiacetic acid that allow the DNA binding to be controlled by a metal ion 京大/阪大/ソウル大合同シンポジウム ,吹田(大阪大学) 京大/阪大/ソウル大合同シンポジウム ,吹田(大阪大学) 2010/05/20 Refereed English Disclose to all
Takayama K ,Nakase Ikuhiko, Michiue Hiroyuki, Takeuchi Toshihide, Tomizawa Kazuhito, Matsui Hideki, Futaki Shiroh Takayama K ,Nakase Ikuhiko, Michiue Hiroyuki, Takeuchi Toshihide, Tomizawa Kazuhito, Matsui Hideki, Futaki Shiroh Promoted cellular uptake of arginine-rich peptides bearing penetration accelerating sequences (Pas) Promoted cellular uptake of arginine-rich peptides bearing penetration accelerating sequences (Pas) 3rd Asia-Pacific International Peptide Symposium ,Jeju, Korea 3rd Asia-Pacific International Peptide Symposium ,Jeju, Korea 2009/11/08 Refereed English Disclose to all
Azuma Y ,Imanisi M, Yoshimura T, Kawabata T, Futaki, S Azuma Y ,Imanisi M, Yoshimura T, Kawabata T, Futaki, S Co(II)-responsive DNA binding switch of the designed GCN4-bZIP protein bearing cysteine moieties functionalized with iminodiacetic acids (Ida) Co(II)-responsive DNA binding switch of the designed GCN4-bZIP protein bearing cysteine moieties functionalized with iminodiacetic acids (Ida) 2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,Tokyo 2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,Tokyo 2009/11/01 Refereed English Disclose to all
Noshiro D ,Asami K, Futaki S Noshiro D ,Asami K, Futaki S Stabilization of the Channel Peptide Assembly: Metal Coordination with an Additional Histidine Yielded Extremely Stable Channels Stabilization of the Channel Peptide Assembly: Metal Coordination with an Additional Histidine Yielded Extremely Stable Channels 2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,東京 2nd Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS09) ,東京 2009/09/12 Refereed English Disclose to all
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Design and creation of a metal-responsive GCN4-bZIP protein modified with iminodiacetic acid (Ida) Design and creation of a metal-responsive GCN4-bZIP protein modified with iminodiacetic acid (Ida) 2nd International Symposium on Bioinorganic Chemimstry of the New Era ,Takayama 2nd International Symposium on Bioinorganic Chemimstry of the New Era ,Takayama 2009/08/02 Refereed English Disclose to all
Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Azuma Y ,Imanishi M, Yoshimura T, Kawabata T, Futaki S Metal-induced DNA-binding switch of bZIP proteins modified with iminodiacetic acid (Ida) Metal-induced DNA-binding switch of bZIP proteins modified with iminodiacetic acid (Ida) The Fifth iCeMS International Symposium, Biomaterials at the interface of chemistry, physics, and biology ,Kyoto The Fifth iCeMS International Symposium, Biomaterials at the interface of chemistry, physics, and biology ,Kyoto 2009/07/27 Refereed English Disclose to all
Takayama K ,Tadokoro A, Nakase I, Futaki S Takayama K ,Tadokoro A, Nakase I, Futaki S Facile One-Pot Modification with Oligoarginine for Intracellular Delivery Facile One-Pot Modification with Oligoarginine for Intracellular Delivery 第45回 ペプチド討論会The 46th Japanese Peptide Symposium ,東京 第45回 ペプチド討論会The 46th Japanese Peptide Symposium ,東京 2008/10/29 Refereed English Disclose to all
Imanishi M ,Nakamura A, Futaki S Imanishi M ,Nakamura A, Futaki S Artificial Zinc Finger-Type Transcription Factors Targeting Circadian Clock Genes Artificial Zinc Finger-Type Transcription Factors Targeting Circadian Clock Genes Chemistry in the New World of Bioengineering and Synthetic Biology ,Oxford, UK Chemistry in the New World of Bioengineering and Synthetic Biology ,Oxford, UK 2008/09/22 Refereed English Disclose to all
Nakase I ,Kobayashi S, Kawabata N, Futaki S Nakase I ,Kobayashi S, Kawabata N, Futaki S Novel Intracellular Delivery System using pH-Dependent Fusiogenic Peptide Novel Intracellular Delivery System using pH-Dependent Fusiogenic Peptide 30th European Peptide Symposium ,Helsinki, Finland 30th European Peptide Symposium ,Helsinki, Finland 2008/09/02 Refereed English Disclose to all
Nakase I ,Hirose H, Takeuchi T, Futaki S Nakase I ,Hirose H, Takeuchi T, Futaki S Effective Macropinocytosis Induction and Membrane Penetration by FHV Peptide Effective Macropinocytosis Induction and Membrane Penetration by FHV Peptide Cell-Penetrating Peptides (CPP) Satellite Symposium of 30th European Peptide Symposium ,Helsinki, Finland Cell-Penetrating Peptides (CPP) Satellite Symposium of 30th European Peptide Symposium ,Helsinki, Finland 2008/08/31 Refereed English Disclose to all
Takayama K ,Takayama K, Takeuchi T, Nakase I, Futaki S Takayama K ,Takayama K, Takeuchi T, Nakase I, Futaki S Rapid Cellular Uptake of Octaarginine-Based Peptides Bearing Hydrophobic Amino Acid Sequences Rapid Cellular Uptake of Octaarginine-Based Peptides Bearing Hydrophobic Amino Acid Sequences 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008" ,Cardiff, UK 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008" ,Cardiff, UK 2008/06/23 Refereed English Disclose to all
Takayama K ,Hayashi Y, Suehisa Y, Fujita T, Yamamoto A,Futaki S, Kiso Y Takayama K ,Hayashi Y, Suehisa Y, Fujita T, Yamamoto A,Futaki S, Kiso Y An Oligoarginine-Based Cargo-Transporter System for Improving Drug Intestinal Absorption: Utilization of Self-Cleavable Peptide Linkers An Oligoarginine-Based Cargo-Transporter System for Improving Drug Intestinal Absorption: Utilization of Self-Cleavable Peptide Linkers Cell penetrating peptides: A Biochemical Society Focused Meeting ,Telford, UK Cell penetrating peptides: A Biochemical Society Focused Meeting ,Telford, UK 2007/05/11 Refereed English Disclose to all
Suzuki T, Futaki S, Niwa M, Nakase I, Tanaka S, Ueda K, Sugiura Y Suzuki T, Futaki S, Niwa M, Nakase I, Tanaka S, Ueda K, Sugiura Y Involvement of Sulfated Glycosaminoglycans with the Internalization of Basic Peptides Involvement of Sulfated Glycosaminoglycans with the Internalization of Basic Peptides Peptide science : proceedings of the ... Japanese Peptide Symposium, 2001, 221-224 , 2001, 221-224 Peptide science : proceedings of the ... Japanese Peptide Symposium, 2001, 221-224 2002/03/01 Refereed English Disclose to all

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Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Modulating Lipid Packing of Cell Membranes for the Access to Cell Interiors[Invited] Modulating Lipid Packing of Cell Membranes for the Access to Cell Interiors [Invited] Modulating Lipid Packing of Cell Membranes for the Access to Cell Interiors [Invited] Chemistry and Biology of Peptides 2019 Chemistry and Biology of Peptides 2019 Chemistry and Biology of Peptides 2019 2019/07/25 English Oral presentation(invited, special) Disclose to all
Redesigning Cationic Lytic Peptides to Promote the Delivery of Biomacromolecules into Cell Interiors Redesigning Cationic Lytic Peptides to Promote the Delivery of Biomacromolecules into Cell Interiors Redesigning Cationic Lytic Peptides to Promote the Delivery of Biomacromolecules into Cell Interiors 26th American Peptide Symposium/11th International Peptide Symposium 26th American Peptide Symposium/11th International Peptide Symposium 26th American Peptide Symposium/11th International Peptide Symposium 2019/06/26 English Oral presentation(general) Disclose to all
Cytosolic Delivery of Biomacromolecules[Invited] Cytosolic Delivery of Biomacromolecules [Invited] Cytosolic Delivery of Biomacromolecules [Invited] 7th Indian Peptide Society 7th Indian Peptide Society 7th Indian Peptide Society 2019/02/28 English Oral presentation(invited, special) Disclose to all
Intracellular delivery of bioactive molecules using peptides[Invited] ペプチドを用いた生理活性分子の細胞内送達 [Invited] Intracellular delivery of bioactive molecules using peptides [Invited] Niigata Hybrid conference 2018 Niigata Hybrid conference 2018 Niigata Hybrid conference 2018 2019/02/09 Japanese Oral presentation(invited, special) Disclose to all
創薬テクノロジー[Invited] 創薬テクノロジー [Invited] 奈良女子大学大学院人間分化研究科講義 「生体防御科学特論」 奈良女子大学大学院人間分化研究科講義 「生体防御科学特論」 2019/01/10 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules[Invited] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited] 10th International Peptide Symposium/55th Japanese Peptide Symposium 10th International Peptide Symposium/55th Japanese Peptide Symposium 10th International Peptide Symposium/55th Japanese Peptide Symposium 2018/12/06 English Oral presentation(invited, special) Disclose to all
Intracellular delivery using peptides[Invited] Intracellular delivery using peptides [Invited] Intracellular delivery using peptides [Invited] 名古屋市大学大学院講義 「センサーデバイス開発学」 名古屋市大学大学院講義 「センサーデバイス開発学」 2018/11/15 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules[Invited] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules [Invited] 8th Peptide Engineering Meeting (PEM8-2018) 8th Peptide Engineering Meeting (PEM8-2018) 8th Peptide Engineering Meeting (PEM8-2018) 2018/11/08 English Oral presentation(invited, special) Disclose to all
Lipid packing loosening promotes the cellular entry of oligoarginine[Invited] Lipid packing loosening promotes the cellular entry of oligoarginine [Invited] Lipid packing loosening promotes the cellular entry of oligoarginine [Invited] The Third A3 Roundtable Meeting on Chemical Probe Research Hub The Third A3 Roundtable Meeting on Chemical Probe Research Hub The Third A3 Roundtable Meeting on Chemical Probe Research Hub 2018/10/31 English Oral presentation(invited, special) Disclose to all
Peptide-mediated delivery of antibodies and bioactive proteins into cells[Invited] Peptide-mediated delivery of antibodies and bioactive proteins into cells [Invited] Peptide-mediated delivery of antibodies and bioactive proteins into cells [Invited] 2018 MDO/JSSX in Kanazawa 2018 MDO/JSSX in Kanazawa 2018 MDO/JSSX in Kanazawa 2018/10/03 English Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞膜の構造・物性変換[Invited] ペプチドを用いた細胞膜の構造・物性変換 [Invited] 第91回日本生化学会大会 第91回日本生化学会大会 2018/09/25 Japanese Oral presentation(invited, special) Disclose to all
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Frontiers in Delivery of Therapeutics Frontiers in Delivery of Therapeutics Frontiers in Delivery of Therapeutics 2018/09/03 English Oral presentation(invited, special) Disclose to all
Cytosolic Delivery of Biomacromolecules[Invited] Cytosolic Delivery of Biomacromolecules [Invited] Cytosolic Delivery of Biomacromolecules [Invited] 17th Akabori Conference: Japanese-German Symposium on Peptide Science 17th Akabori Conference: Japanese-German Symposium on Peptide Science 17th Akabori Conference: Japanese-German Symposium on Peptide Science 2018/09/03 English Oral presentation(invited, special) Disclose to all
Cytosolic Delivery of Biomacromolecules[Invited] Cytosolic Delivery of Biomacromolecules [Invited] Cytosolic Delivery of Biomacromolecules [Invited] 15th Chinese International Peptide Symposium 15th Chinese International Peptide Symposium 15th Chinese International Peptide Symposium 2018/07/04 English Oral presentation(invited, special) Disclose to all
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] 22th Korean Peptide Protein Society (KPPS) Symposium 22th Korean Peptide Protein Society (KPPS) Symposium 22th Korean Peptide Protein Society (KPPS) Symposium 2018/06/25 English Oral presentation(keynote) Disclose to all
ペプチドを用いた生理活性分子の細胞内送達 ペプチドを用いた生理活性分子の細胞内送達 日本ケミカルバイオロジー学会第13回年会 日本ケミカルバイオロジー学会第13回年会 2018/06/11 Japanese Oral presentation(invited, special) Disclose to all
クモ毒を改良し抗体を細胞内へ輸送[Invited] クモ毒を改良し抗体を細胞内へ輸送 [Invited] バイオファーマジャパン(第6回) バイオファーマジャパン(第6回) 2018/04/20 Japanese Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 第393回CBI学会講演会「中分子創薬の実現にむけて」 第393回CBI学会講演会「中分子創薬の実現にむけて」 2018/03/16 Japanese Oral presentation(invited, special) Disclose to all
Cytosolic Antibody Delivery by Lipid-sensitive Endosomolytic Peptide[Invited] Cytosolic Antibody Delivery by Lipid-sensitive Endosomolytic Peptide [Invited] Cytosolic Antibody Delivery by Lipid-sensitive Endosomolytic Peptide [Invited] IRCCS-JST CREST Joint Symposium “Chemical sciences facing difficult challenges” IRCCS-JST CREST Joint Symposium “Chemical sciences facing difficult challenges” IRCCS-JST CREST Joint Symposium “Chemical sciences facing difficult challenges” 2018/01/24 English Oral presentation(invited, special) Disclose to all
Cytosolic delivery of biomacromolecules[Invited] Cytosolic delivery of biomacromolecules [Invited] Cytosolic delivery of biomacromolecules [Invited] 2018 International Symposium on Chemical Biology 2018 International Symposium on Chemical Biology 2018 International Symposium on Chemical Biology 2018/01/11 English Oral presentation(keynote) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 九州大学先導物質化学研究所講演会 九州大学先導物質化学研究所講演会 2017/11/30 Japanese Oral presentation(invited, special) Disclose to all
Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide[Invited] Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide [Invited] Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide [Invited] The Second A3 Roundtable Meeting on Chemical Probe Research Hub The Second A3 Roundtable Meeting on Chemical Probe Research Hub The Second A3 Roundtable Meeting on Chemical Probe Research Hub 2017/11/24 English Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞内デリバリー ペプチドを用いた細胞内デリバリー 第54回ペプチド討論会 第54回ペプチド討論会 2017/11/21 Japanese Symposium workshop panel(nominated) Disclose to all
Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] Peptide-mediated Delivery of Biomacromolecules into Cells [Invited] 12th Australian Peptide Conference 2017 12th Australian Peptide Conference 2017 12th Australian Peptide Conference 2017 2017/10/17 English Oral presentation(invited, special) Disclose to all
細胞内デリバリーペプチドの膜との相互作用[Invited] 細胞内デリバリーペプチドの膜との相互作用 [Invited] 17-1 バイオ・高分子研究会 17-1 バイオ・高分子研究会 2017/09/22 Japanese Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 伊那ケミカルバイオロジーセミナー 伊那ケミカルバイオロジーセミナー 2017/07/14 Japanese Oral presentation(invited, special) Disclose to all
Loosening of the Lipid Packing by Curvature Inducing Peptides Promotes Cell Entry of Oligoarginine Loosening of the Lipid Packing by Curvature Inducing Peptides Promotes Cell Entry of Oligoarginine Loosening of the Lipid Packing by Curvature Inducing Peptides Promotes Cell Entry of Oligoarginine 25th American Peptide Symposium 25th American Peptide Symposium 25th American Peptide Symposium 2017/06/21 English Oral presentation(general) Disclose to all
Redesigning Hemolytic Peptides for Cytosolic Antibody Delivery Redesigning Hemolytic Peptides for Cytosolic Antibody Delivery Redesigning Hemolytic Peptides for Cytosolic Antibody Delivery 25th American Peptide Symposium 25th American Peptide Symposium 25th American Peptide Symposium 2017/06/19 English Poster presentation Disclose to all
生物機能中分子の細胞内へ導入基盤の創出[Invited] 生物機能中分子の細胞内へ導入基盤の創出 [Invited] 日本薬学会第137年会(仙台) シンポジウム「中分子創薬研究のフロンティア−反応集積化が導く中分子戦略:高次生物機能分子の創製−」 日本薬学会第137年会(仙台) シンポジウム「中分子創薬研究のフロンティア−反応集積化が導く中分子戦略:高次生物機能分子の創製−」 2017/03/27 Japanese Symposium workshop panel(nominated) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 第3回 新学術領域研究「中分子戦略」若手シンポジウム 第3回 新学術領域研究「中分子戦略」若手シンポジウム 2017/03/07 Japanese Oral presentation(invited, special) Disclose to all
ペプチドの膜との相互作用・膜透過[Invited] ペプチドの膜との相互作用・膜透過 [Invited] 平成28年度特別経費事業 (創薬人育成のための創薬実践道場教育構築事業) (多機能性人工エキソソーム(iTEX)医薬品化実践を通じた操薬人育成事業) 合同シンポジウム 平成28年度特別経費事業 (創薬人育成のための創薬実践道場教育構築事業) (多機能性人工エキソソーム(iTEX)医薬品化実践を通じた操薬人育成事業) 合同シンポジウム 2017/02/13 Japanese Oral presentation(invited, special) Disclose to all
生命を支えるペプチド:そのはたらきと可能性 生命を支えるペプチド:そのはたらきと可能性 京都大学化学研究所講演会 京都大学化学研究所講演会 2016/10/23 Japanese Symposium workshop panel(nominated) Disclose to all
見る・知る・作る:ペプチドと細胞膜との相互作用[Invited] 見る・知る・作る:ペプチドと細胞膜との相互作用 [Invited] 第9回東京大学化学生命工学専攻ChemBioハイブリッドレクチャー 第9回東京大学化学生命工学専攻ChemBioハイブリッドレクチャー 2016/10/08 Japanese Oral presentation(invited, special) Disclose to all
ペプチドの膜との相互作用・膜透過[Invited] ペプチドの膜との相互作用・膜透過 [Invited] 遺伝子・デリバリー研究会 第16回夏期セミナー 遺伝子・デリバリー研究会 第16回夏期セミナー 2016/09/13 Japanese Oral presentation(invited, special) Disclose to all
Photocrosslinking approaches to identify cellular-uptake receptors of arginine-rich cell-penetrating peptides[Invited] Photocrosslinking approaches to identify cellular-uptake receptors of arginine-rich cell-penetrating peptides [Invited] Photocrosslinking approaches to identify cellular-uptake receptors of arginine-rich cell-penetrating peptides [Invited] 34th European Peptide Symposium and 8th International Peptide Symposium 34th European Peptide Symposium and 8th International Peptide Symposium 34th European Peptide Symposium and 8th International Peptide Symposium 2016/09/09 English Oral presentation(keynote) Disclose to all
Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides[Invited] Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides [Invited] Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides [Invited] 14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5) 14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5) 14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5) 2016/07/07 English Oral presentation(invited, special) Disclose to all
生物機能中分子の細胞内への新規導入基盤の創出 生物機能中分子の細胞内への新規導入基盤の創出 新学術領域「反応集積化が導く中分子戦略:高次生物機能分子の創製」 第2回公開成果報告会 新学術領域「反応集積化が導く中分子戦略:高次生物機能分子の創製」 第2回公開成果報告会 2016/07/03 Japanese Symposium workshop panel(nominated) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 創薬懇話会2016 in蓼科:次世代を担う若手のためのメディシナルケミストリーフォーラム 創薬懇話会2016 in蓼科:次世代を担う若手のためのメディシナルケミストリーフォーラム 2016/07/01 Japanese Oral presentation(invited, special) Disclose to all
Membrane-remodeling Amphypathic Helical Peptides Accelerate Direct Penetration of Octaarginine[Invited] Membrane-remodeling Amphypathic Helical Peptides Accelerate Direct Penetration of Octaarginine [Invited] Membrane-remodeling Amphypathic Helical Peptides Accelerate Direct Penetration of Octaarginine [Invited] 20th Korea Peptide Protein Society (KPPS) Symposium 20th Korea Peptide Protein Society (KPPS) Symposium 20th Korea Peptide Protein Society (KPPS) Symposium 2016/06/25 English Oral presentation(invited, special) Disclose to all
Novel Lysosomolytic Peptides to Achieve Cytoplasmic Distribution of Biomacromolecules[Invited] Novel Lysosomolytic Peptides to Achieve Cytoplasmic Distribution of Biomacromolecules [Invited] Novel Lysosomolytic Peptides to Achieve Cytoplasmic Distribution of Biomacromolecules [Invited] The 16th Akabori Conference: Japanese-German Symposium On Peptide Science The 16th Akabori Conference: Japanese-German Symposium On Peptide Science The 16th Akabori Conference: Japanese-German Symposium On Peptide Science 2016/05/24 English Oral presentation(invited, special) Disclose to all
光架橋法による膜透過ペプチドの取込受容体の同定と機序解明[Invited] 光架橋法による膜透過ペプチドの取込受容体の同定と機序解明 [Invited] 日本農芸化学会2016年度(平成28年度)大会 シンポジウム「光プローブによるタンパク質プロファイリングと創薬」 日本農芸化学会2016年度(平成28年度)大会 シンポジウム「光プローブによるタンパク質プロファイリングと創薬」 2016/03/27 Japanese Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞内デリバリー[Invited] ペプチドを用いた細胞内デリバリー [Invited] 第22回ペプチドフォーラム 第22回ペプチドフォーラム 2016/03/05 Japanese Oral presentation(invited, special) Disclose to all
Peptide Mediated Delivery of Bioactive Proteins into Cells[Invited] Peptide Mediated Delivery of Bioactive Proteins into Cells [Invited] Peptide Mediated Delivery of Bioactive Proteins into Cells [Invited] 8th AsiaTIDES 8th AsiaTIDES 8th AsiaTIDES 2016/02/24 English Oral presentation(invited, special) Disclose to all
Membrane translocation of arginine-rich peptides and the effect of membrane curvature [Invited] Membrane translocation of arginine-rich peptides and the effect of membrane curvature [Invited] Membrane translocation of arginine-rich peptides and the effect of membrane curvature [Invited] The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) 2015/12/19 English Oral presentation(invited, special) Disclose to all
Exploiting hemolytic amphiphilic peptides as a design template for cytosolic antibody delivery[Invited] Exploiting hemolytic amphiphilic peptides as a design template for cytosolic antibody delivery [Invited] Exploiting hemolytic amphiphilic peptides as a design template for cytosolic antibody delivery [Invited] The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015) 2015/12/17 English Oral presentation(invited, special) Disclose to all
Peptide mediated delivery of bioactive proteins into cells[Invited] Peptide mediated delivery of bioactive proteins into cells [Invited] Peptide mediated delivery of bioactive proteins into cells [Invited] The 7th International Peptide Symposium The 7th International Peptide Symposium The 7th International Peptide Symposium 2015/12/09 English Oral presentation(invited, special) Disclose to all
A novel lysosomolytic peptide designed from spider venom[Invited] A novel lysosomolytic peptide designed from spider venom [Invited] A novel lysosomolytic peptide designed from spider venom [Invited] 7th Peptide Engineering Meeting (PEM7-2015) 7th Peptide Engineering Meeting (PEM7-2015) 7th Peptide Engineering Meeting (PEM7-2015) 2015/12/06 English Oral presentation(invited, special) Disclose to all
Converting a cytotoxic, hemolytic peptide to an intracellular delivery tool of bioactive proteins[Invited] Converting a cytotoxic, hemolytic peptide to an intracellular delivery tool of bioactive proteins [Invited] Converting a cytotoxic, hemolytic peptide to an intracellular delivery tool of bioactive proteins [Invited] NEA & ASIAHORCs Joint Symposium on Chemical Biology NEA & ASIAHORCs Joint Symposium on Chemical Biology NEA & ASIAHORCs Joint Symposium on Chemical Biology 2015/11/10 English Oral presentation(invited, special) Disclose to all
アミノ酸・ペプチドは体の調子を整える[Invited] アミノ酸・ペプチドは体の調子を整える [Invited] ひょうご講座2015「健康をサイエンスする」第6回 ひょうご講座2015「健康をサイエンスする」第6回 2015/10/06 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
細胞の営みを探る[Invited] 細胞の営みを探る [Invited] ひょうご講座2015「健康をサイエンスする」第2回 ひょうご講座2015「健康をサイエンスする」第2回 2015/09/15 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Peptide-based approaches for delivering exogenous molecules into cells[Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery" International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery" International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery" 2015/07/03 English Oral presentation(invited, special) Disclose to all
ペプチド相互認識を用いた膜タンパク質の会合制御[Invited] ペプチド相互認識を用いた膜タンパク質の会合制御 [Invited] 日本薬学会第135年会(神戸) シンポジウム 「タンパク質の会合・凝集:計測、メカニズムから制御まで」 日本薬学会第135年会(神戸) シンポジウム 「タンパク質の会合・凝集:計測、メカニズムから制御まで」 2015/03/26 Japanese Symposium workshop panel(nominated) Disclose to all
ペプチド相互認識を用いた膜タンパク質の会合制御[Invited] ペプチド相互認識を用いた膜タンパク質の会合制御 [Invited] 日本薬学会第135年会(神戸) シンポジウム 「タンパク質の会合・凝集:計測、メカニズムから制御まで」 日本薬学会第135年会(神戸) シンポジウム 「タンパク質の会合・凝集:計測、メカニズムから制御まで」 2015/03/25 Japanese Oral presentation(invited, special) Disclose to all
Asian Chemical Biology Conference 3 (ACBC3 2014)[Invited] Asian Chemical Biology Conference 3 (ACBC3 2014) [Invited] Asian Chemical Biology Conference 3 (ACBC3 2014) [Invited] Peptide-based approaches for delivering exogenous molecules into cells Peptide-based approaches for delivering exogenous molecules into cells Peptide-based approaches for delivering exogenous molecules into cells 2014/12/16 English Oral presentation(invited, special) Disclose to all
Peptide-based approaches for delivering exogenous molecules into cells[Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] Asian Chemical Biology Conference 3 (ACBC3 2014) Asian Chemical Biology Conference 3 (ACBC3 2014) Asian Chemical Biology Conference 3 (ACBC3 2014) 2014/12/16 English Oral presentation(invited, special) Disclose to all
薬を患部に運ぶには?[Invited] 薬を患部に運ぶには? [Invited] ひょうご講座2014「健康サイエンス」第6回 ひょうご講座2014「健康サイエンス」第6回 2014/10/28 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
体に役立つアミノ酸・ペプチド[Invited] 体に役立つアミノ酸・ペプチド [Invited] ひょうご講座2014「健康サイエンス」第5回 ひょうご講座2014「健康サイエンス」第5回 2014/10/14 Japanese Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine[Invited] Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine [Invited] Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine [Invited] The Sino-Japan Workshop on Chemical Biology The Sino-Japan Workshop on Chemical Biology The Sino-Japan Workshop on Chemical Biology 2014/10/11 English Oral presentation(invited, special) Disclose to all
Extramembrane control of peptide/protein assembly[Invited] Extramembrane control of peptide/protein assembly [Invited] Extramembrane control of peptide/protein assembly [Invited] Workshop on Artificial Photosynthesis: Engineering of Light-Harvesting Processes based on Peptide and Protein Science Workshop on Artificial Photosynthesis: Engineering of Light-Harvesting Processes based on Peptide and Protein Science Workshop on Artificial Photosynthesis: Engineering of Light-Harvesting Processes based on Peptide and Protein Science 2014/10/06 English Oral presentation(invited, special) Disclose to all
Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine Swiss-Japanese Chemical Biology Symposium 2014 Swiss-Japanese Chemical Biology Symposium 2014 Swiss-Japanese Chemical Biology Symposium 2014 2014/10/02 English Poster presentation Disclose to all
Membrane translocation of arginine-rich cell-penetrating peptides and the effect of membrane curvature[Invited] Positive membrane curvature induced by epsin N-terminal peptide accelerates internalization of octaarginine [Invited] Membrane translocation of arginine-rich cell-penetrating peptides and the effect of membrane curvature [Invited] Karlsruher Institut für Technologie (KIT), special lecture Karlsruher Institut für Technologie (KIT), special lecture Karlsruher Institut für Technologie (KIT), special lecture 2014/09/09 English Oral presentation(invited, special) Disclose to all
Engineering membrane curvatures by peptides[Invited] Engineering membrane curvatures by peptides [Invited] Engineering membrane curvatures by peptides [Invited] 15th Akabori Conference 15th Akabori Conference 15th Akabori Conference 2014/09/08 English Oral presentation(invited, special) Disclose to all
Positive membrane curvature induced by epsin n-terminal peptide boosts translocation of oligoarginine through biological membranes: an approach towards curvature engineering Positive membrane curvature induced by epsin n-terminal peptide boosts translocation of oligoarginine through biological membranes: an approach towards curvature engineering Positive membrane curvature induced by epsin n-terminal peptide boosts translocation of oligoarginine through biological membranes: an approach towards curvature engineering 33rd European Peptide Symposium 33rd European Peptide Symposium 33rd European Peptide Symposium 2014/08/31 English Oral presentation(general) Disclose to all
膜と相互作用する(面白い?)ペプチド[Invited] 膜と相互作用する(面白い?)ペプチド [Invited] 第46回若手ペプチド夏の勉強会 第46回若手ペプチド夏の勉強会 2014/08/04 Japanese Oral presentation(invited, special) Disclose to all
薬物送達・ケミカルバイオロジーツールとしてのペプチド[Invited] 薬物送達・ケミカルバイオロジーツールとしてのペプチド [Invited] 日本薬学会北陸支部特別講演会 日本薬学会北陸支部特別講演会 2014/06/21 Japanese Oral presentation(invited, special) Disclose to all
Arginine-rich peptide vectors for intracellular delivery[Invited] Arginine-rich peptide vectors for intracellular delivery [Invited] Arginine-rich peptide vectors for intracellular delivery [Invited] Ewha-Kyoto PI Research Meeting 2014 Ewha-Kyoto PI Research Meeting 2014 Ewha-Kyoto PI Research Meeting 2014 2014/06/16 English Oral presentation(invited, special) Disclose to all
Peptide-based approaches for delivering exogenous molecules into cells[Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] The 3rd International Conference on MEXT Project of Integrated Research on Chemical Synthesis The 3rd International Conference on MEXT Project of Integrated Research on Chemical Synthesis The 3rd International Conference on MEXT Project of Integrated Research on Chemical Synthesis 2014/01/11 English Oral presentation(invited, special) Disclose to all
アルギニンペプチドの膜透過と膜曲率[Invited] アルギニンペプチドの膜透過と膜曲率 [Invited] 第86回日本生化学会大会 シンポジウム「生体膜の動態から見える新たな膜生物学」 第86回日本生化学会大会 シンポジウム「生体膜の動態から見える新たな膜生物学」 2013/09/13 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いる細胞への蛋白質導入技術[Invited] 膜透過ペプチドを用いる細胞への蛋白質導入技術 [Invited] 第65回日本細胞生物学会大会 シンポジウム「細胞への蛋白質導入技術と蛋白質イメージング技術」 第65回日本細胞生物学会大会 シンポジウム「細胞への蛋白質導入技術と蛋白質イメージング技術」 2013/06/19 Japanese Oral presentation(invited, special) Disclose to all
膜と相互作用する機能性ペプチド[Invited] 膜と相互作用する機能性ペプチド [Invited] 東京医科歯科大学生体材料工学研究所 146th IBB Seminar 東京医科歯科大学生体材料工学研究所 146th IBB Seminar 2013/01/08 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞膜透過とその要因 アルギニンペプチドの細胞膜透過とその要因 日本ペプチド学会第16回ペプチドフォーラム「ペプチドと膜とのインタープレイ:新しい視点と可能性を探る」 日本ペプチド学会第16回ペプチドフォーラム「ペプチドと膜とのインタープレイ:新しい視点と可能性を探る」 宇治 宇治 2012/12/21 Japanese Oral presentation(invited, special) Disclose to all
有機合成化学の多様性の魅力 -多様性を生み出す発想力を学ぶ 有機合成化学の多様性の魅力 -多様性を生み出す発想力を学ぶ 有機合成化学協会 平成24年度 後期(秋季)有機合成化学講習会 有機合成化学協会 平成24年度 後期(秋季)有機合成化学講習会 東京 東京 2012/11/20 Japanese Oral presentation(invited, special) Disclose to all
ジンクフィンガーモチーフを用いた人工転写因子の創製と応用 ジンクフィンガーモチーフを用いた人工転写因子の創製と応用 ナノバイオ研究会 ナノバイオ研究会 名古屋(名古屋工業大学) 名古屋(名古屋工業大学) 2012/11/14 Japanese Oral presentation(invited, special) Disclose to all
New Functions of Zinc Fingers Revealed by Substitution of Conserved Residues New Functions of Zinc Fingers Revealed by Substitution of Conserved Residues 第50回日本生物物理学会年会 第50回日本生物物理学会年会 名古屋(名古屋大学) 名古屋(名古屋大学) 2012/09/22 Japanese Oral presentation(invited, special) Disclose to all
細胞機能探索に有用なペプチドツール?細胞内導入と受容体創製? 細胞機能探索に有用なペプチドツール?細胞内導入と受容体創製? サントリー生命科学財団 生物有機科学研究所シンポジウム サントリー生命科学財団 生物有機科学研究所シンポジウム 京都(サントリー生命科学財団 生物有機科学研究所) 京都(サントリー生命科学財団 生物有機科学研究所) 2012/08/27 Japanese Oral presentation(invited, special) Disclose to all
膜透過性ペプチドの効率的な細胞内移行 膜透過性ペプチドの効率的な細胞内移行 第12回日本蛋白質科学会年会 第12回日本蛋白質科学会年会 名古屋(名古屋国際会議場) 名古屋(名古屋国際会議場) 2012/06/20 Japanese Oral presentation(invited, special) Disclose to all
薬物送達・ケミカルバイオロジーツールとしてのペプチド 薬物送達・ケミカルバイオロジーツールとしてのペプチド 大阪市立大学大学院工学研究科特別講義講演会 大阪市立大学大学院工学研究科特別講義講演会 大阪 大阪 2012/06/19 Japanese Oral presentation(invited, special) Disclose to all
人工DNA結合タンパク質のデザインと細胞機能制御への展開 人工DNA結合タンパク質のデザインと細胞機能制御への展開 日本薬学会第132年会 日本薬学会第132年会 札幌 札幌 2012/03/30 Japanese Oral presentation(invited, special) Disclose to all
ジンクフィンガー型人工転写因子の創製と細胞機能の制御 ジンクフィンガー型人工転写因子の創製と細胞機能の制御 日本薬学会第132年会 日本薬学会第132年会 札幌 札幌 2012/03/29 Japanese Oral presentation(invited, special) Disclose to all
細胞膜透過ペプチドとDDS 細胞膜透過ペプチドとDDS 大分県病院薬剤師会2月例会 大分県病院薬剤師会2月例会 大分 大分 2012/02/03 Japanese Oral presentation(invited, special) Disclose to all
鹿児島、金属によるペプチドの構造と機能スイッチ 鹿児島、金属によるペプチドの構造と機能スイッチ 第14回ペプチドフォーラム 第14回ペプチドフォーラム 鹿児島 鹿児島 2011/12/16 Japanese Oral presentation(invited, special) Disclose to all
ジンクフィンガー型人工転写因子を用いた細胞時計の制御 ジンクフィンガー型人工転写因子を用いた細胞時計の制御 日本ケミカルバイオロジー学会第6回年会 日本ケミカルバイオロジー学会第6回年会 東京(東京工業大学) 東京(東京工業大学) 2011/05/25 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドの生体膜透過機構とそれを利用した高分子の細胞内送達 膜透過ペプチドの生体膜透過機構とそれを利用した高分子の細胞内送達 日本膜学会第33年会 生体膜関連シンポジウム 「高分子と生体膜の相互作用を利用した新たな治療戦略」 日本膜学会第33年会 生体膜関連シンポジウム 「高分子と生体膜の相互作用を利用した新たな治療戦略」 東京(産業技術総合研究所) 東京(産業技術総合研究所) 2011/05/13 Japanese Oral presentation(invited, special) Disclose to all
Peptide-based approaches to deliver biomacromolecules into cells(ペプチドを用いた細胞内への生理活性高分子送達の試み) Peptide-based approaches to deliver biomacromolecules into cells(ペプチドを用いた細胞内への生理活性高分子送達の試み) 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会 ワークショップ「遺伝子デリバリーのセルバリア:その解明と克服」 第33回日本分子生物学会年会・第83回日本生化学会大会合同大会 ワークショップ「遺伝子デリバリーのセルバリア:その解明と克服」 神戸 神戸 2010/12/09 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの生体膜透過 アルギニンペプチドの生体膜透過 次世代スーパーコンピュータプロジェクト ナノ分野グランドチャレンジ研究開発 連続研究会:イオンチャネル(No.2) 次世代スーパーコンピュータプロジェクト ナノ分野グランドチャレンジ研究開発 連続研究会:イオンチャネル(No.2) 福井 福井 2010/12/02 Japanese Oral presentation(invited, special) Disclose to all
からだの中の細胞を観る からだの中の細胞を観る ひょうご講座2010 バイオテクノロジーと未来生活 ひょうご講座2010 バイオテクノロジーと未来生活 神戸 神戸 2010/11/13 Japanese Oral presentation(invited, special) Disclose to all
バイオテクノロジーと食品・医薬 バイオテクノロジーと食品・医薬 ひょうご講座2010 バイオテクノロジーと未来生活 ひょうご講座2010 バイオテクノロジーと未来生活 神戸 神戸 2010/11/06 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドと細胞膜関連分子との相互作用と細胞内移行 アルギニンペプチドと細胞膜関連分子との相互作用と細胞内移行 薬剤学ミニシンポジウム レドックスとアルブミンDDSの融合 薬剤学ミニシンポジウム レドックスとアルブミンDDSの融合 熊本 熊本 2010/05/18 Japanese Oral presentation(invited, special) Disclose to all
Chemical and biological factors that stimulate internalization of arginine-rich peptides Chemical and biological factors that stimulate internalization of arginine-rich peptides MANA International Symposium 2010 MANA International Symposium 2010 Tsukuba Tsukuba 2010/03/25 Japanese Oral presentation(invited, special) Disclose to all
ペプチドをツールとして用いた生体高分子の細胞内送達技術 ペプチドをツールとして用いた生体高分子の細胞内送達技術 日本化学会第90春季年会 特別企画「化学で切り拓く未来医療」 日本化学会第90春季年会 特別企画「化学で切り拓く未来医療」 東大阪 東大阪 2010/03/25 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの膜透過と細胞内送達 アルギニンペプチドの膜透過と細胞内送達 東京薬科大学生命科学部大学院講義 東京薬科大学生命科学部大学院講義 八王子 八王子 2010/01/15 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いた細胞内導入 アルギニンペプチドを用いた細胞内導入 第5回物質合成シンポジウム 第5回物質合成シンポジウム 宇治 宇治 2009/11/19 Japanese Oral presentation(invited, special) Disclose to all
(7)タンパク質のキノウ (7)タンパク質のキノウ ひょうご講座2009 ナノサイズの生命現象 ひょうご講座2009 ナノサイズの生命現象 神戸 神戸 2009/11/14 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドと細胞膜との相互作用 アルギニンペプチドと細胞膜との相互作用 第82回日本生化学会大会シンポジウム 遺伝子発現のセルバリア:核膜の機能・構造理解とバリア克服 第82回日本生化学会大会シンポジウム 遺伝子発現のセルバリア:核膜の機能・構造理解とバリア克服 神戸 神戸 2009/10/22 Japanese Oral presentation(invited, special) Disclose to all
ペプチドを用いた細胞内デリバリー ペプチドを用いた細胞内デリバリー 近畿バイオインダストリー振興会議 フォローアップ勉強会 近畿バイオインダストリー振興会議 フォローアップ勉強会 大阪 大阪 2009/09/11 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いた蛋白質の細胞内導入 アルギニンペプチドを用いた蛋白質の細胞内導入 2009年度酵素・補酵素研究会 2009年度酵素・補酵素研究会 奈良 奈良 2009/07/11 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドと細胞膜の相互作用 アルギニンペプチドと細胞膜の相互作用 故吉田和哉先生追悼コンビナトリアル・バイオエンジニアリング 特別シンポジウム「新バイオ分子と機能の創出をめざして 10年の軌跡」 故吉田和哉先生追悼コンビナトリアル・バイオエンジニアリング 特別シンポジウム「新バイオ分子と機能の創出をめざして 10年の軌跡」 大阪 大阪 2009/04/30 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いた細胞内移送 アルギニンペプチドを用いた細胞内移送 岡山大学大学院自然科学研究科特別講演会 岡山大学大学院自然科学研究科特別講演会 岡山 岡山 2009/04/22 Japanese Oral presentation(invited, special) Disclose to all
身近な『ペプチド』: いのちの基本からくすりまで 身近な『ペプチド』: いのちの基本からくすりまで キンカ京都化学者クラブ第225回例会 キンカ京都化学者クラブ第225回例会 京都 京都 2009/03/07 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを使った細胞内デリバリー アルギニンペプチドを使った細胞内デリバリー 近畿化学協会バイオ部会平成20年度第2回例会 近畿化学協会バイオ部会平成20年度第2回例会 京都 京都 2009/02/10 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドと細胞内デリバリー アルギニンペプチドと細胞内デリバリー 徳島大学薬学部特別講演会 徳島大学薬学部特別講演会 徳島 徳島 2009/01/16 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いた細胞内デリバリー アルギニンペプチドを用いた細胞内デリバリー 京都薬科大学統合創薬科学フロンティアシンポジウム  〜 伝承薬から生物分子システムまでを基盤として 〜 京都薬科大学統合創薬科学フロンティアシンポジウム  〜 伝承薬から生物分子システムまでを基盤として 〜 京都 京都 2008/12/14 Japanese Oral presentation(invited, special) Disclose to all
Cell penetrating peptideを用いた中枢神経系疾患に対するProtein Therapy に関する基礎研究 Cell penetrating peptideを用いた中枢神経系疾患に対するProtein Therapy に関する基礎研究 第31回日本分子生物学会年会、第81回日本生化学会大会 合同大会 第31回日本分子生物学会年会、第81回日本生化学会大会 合同大会 神戸 神戸 2008/12/09 Japanese Oral presentation(invited, special) Disclose to all
時計遺伝子を標的とした人工転写因子の創製 時計遺伝子を標的とした人工転写因子の創製 第11回生命化学研究会 第11回生命化学研究会 群馬 群馬 2008/11/28 Japanese Oral presentation(invited, special) Disclose to all
ジンクフィンガー型人工転写因子を用いた時計遺伝子プロモーター制御 ジンクフィンガー型人工転写因子を用いた時計遺伝子プロモーター制御 第15回日本時間生物学会学術大会 第15回日本時間生物学会学術大会 岡山 岡山 2008/11/08 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞との相互作用のダイナミクス アルギニンペプチドの細胞との相互作用のダイナミクス 第10回ペプチドフォーラム 「協奏分子としてのアルギニン:細胞・分子機能 における普遍性・必然性とその応用」 第10回ペプチドフォーラム 「協奏分子としてのアルギニン:細胞・分子機能 における普遍性・必然性とその応用」 京都 京都 2008/11/07 Japanese Oral presentation(invited, special) Disclose to all
身近な「ペプチド」:いのちの基本からくすりまで 身近な「ペプチド」:いのちの基本からくすりまで 第15回化学研究所公開講演会 第15回化学研究所公開講演会 宇治 宇治 2008/10/19 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドと生体膜との相互作用 アルギニンペプチドと生体膜との相互作用 Frontier’s Nanomedicine -Summer Workshop 2008- Frontier’s Nanomedicine -Summer Workshop 2008- 札幌 札幌 2008/08/05 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞内移行 アルギニンペプチドの細胞内移行 平成20年度蛋白研セミナー 細胞機能制御システムとしての核膜研究 〜基礎から臨床応用を目指して〜 平成20年度蛋白研セミナー 細胞機能制御システムとしての核膜研究 〜基礎から臨床応用を目指して〜 吹田 吹田 2008/07/25 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞内移行のダイナミクス アルギニンペプチドの細胞内移行のダイナミクス 第14回日本遺伝子治療学会学術集会 第14回日本遺伝子治療学会学術集会 札幌 札幌 2008/06/14 Japanese Oral presentation(invited, special) Disclose to all
膜透ペプチドを用いた細胞内移送 膜透ペプチドを用いた細胞内移送 徳島大学大学院薬学研究科大学院講義「環境生物工学特論」 徳島大学大学院薬学研究科大学院講義「環境生物工学特論」 徳島 徳島 2008/06/02 Japanese Oral presentation(invited, special) Disclose to all
蛋白質・ペプチドの機能設計の基礎 蛋白質・ペプチドの機能設計の基礎 徳島大学薬学部3年次「遺伝子工学」講義 徳島大学薬学部3年次「遺伝子工学」講義 徳島 徳島 2008/06/02 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞膜透過 アルギニンペプチドの細胞膜透過 日本薬学会第128年会シンポジウム「膜を知る・膜を超える:生体膜のダイナミクスと膜透過」 日本薬学会第128年会シンポジウム「膜を知る・膜を超える:生体膜のダイナミクスと膜透過」 横浜 横浜 2008/03/26 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの細胞内移行機序とタンパク質・ナノ粒子のデリバリー アルギニンペプチドの細胞内移行機序とタンパク質・ナノ粒子のデリバリー 5回東京理科大 DDS 研究センターシンポジウム(主題: ナノDDS ) 5回東京理科大 DDS 研究センターシンポジウム(主題: ナノDDS ) 東京 東京 2007/12/21 Japanese Oral presentation(invited, special) Disclose to all
膜と相互作用するペプチドと機能 膜と相互作用するペプチドと機能 九州大学グローバルCOEプログラム「未来システム科学」特別講演会 九州大学グローバルCOEプログラム「未来システム科学」特別講演会 福岡 福岡 2007/10/16 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いる細胞導入技術 膜透過ペプチドを用いる細胞導入技術 Combinatorial Chemistry研究会第25回公開セミナー Combinatorial Chemistry研究会第25回公開セミナー 東京 東京 2007/09/27 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いた細胞内送達 膜透過ペプチドを用いた細胞内送達 第56回高分子討論会 第56回高分子討論会 名古屋 名古屋 2007/09/20 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの膜透過における血清の影響と濃度依存性 アルギニンペプチドの膜透過における血清の影響と濃度依存性 北海道大学薬学部特別講演会 北海道大学薬学部特別講演会 札幌 札幌 2007/08/08 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを使った細胞内デリバリー 膜透過ペプチドを使った細胞内デリバリー 名古屋大学大学院工学研究科講演会 名古屋大学大学院工学研究科講演会 名古屋 名古屋 2007/07/06 Japanese Oral presentation(invited, special) Disclose to all
膜と相互作用するペプチドの機能設計 膜と相互作用するペプチドの機能設計 名古屋大学大学院工学研究科生体材料工学特論 名古屋大学大学院工学研究科生体材料工学特論 名古屋 名古屋 2007/07/05 Japanese Oral presentation(invited, special) Disclose to all
膜と相互作用するペプチドの設計と開発 膜と相互作用するペプチドの設計と開発 東京大学大学院薬学系研究科特別講義 東京大学大学院薬学系研究科特別講義 東京 東京 2006/11/28 Japanese Oral presentation(invited, special) Disclose to all
細胞膜透過ペプチドベクターによる細胞内デリバリー 細胞膜透過ペプチドベクターによる細胞内デリバリー 第44回癌治療学会総会 シンポジウム 薬物デリバリーの現状と未来 第44回癌治療学会総会 シンポジウム 薬物デリバリーの現状と未来 東京 東京 2006/10/19 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いる細胞内デリバリー アルギニンペプチドを用いる細胞内デリバリー 日本化学会近畿支部奈良地区講演会 日本化学会近畿支部奈良地区講演会 生駒 生駒 2006/10/13 Japanese Oral presentation(invited, special) Disclose to all
ペプチドベクターを用いた細胞内導入 ペプチドベクターを用いた細胞内導入 遺伝子・デリバリー研究会第6回夏期セミナー 遺伝子・デリバリー研究会第6回夏期セミナー 箕面 箕面 2006/09/07 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いる送達法の現状と展望 膜透過ペプチドを用いる送達法の現状と展望 日本薬学会第126年会 シンポジウム「経口バイオアベイラビリティを改善する次世代ストラテジー:薬物物性を操作し、生体膜機能を利用する」 日本薬学会第126年会 シンポジウム「経口バイオアベイラビリティを改善する次世代ストラテジー:薬物物性を操作し、生体膜機能を利用する」 仙台 仙台 2006/03/28 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いた細胞内デリバリー 膜透過ペプチドを用いた細胞内デリバリー 星薬科大学特別講義 星薬科大学特別講義 東京 東京 2005/12/22 Japanese Oral presentation(invited, special) Disclose to all
新規なDDS戦略(ペプチドベクターを用いた動物細胞へのタンパク質・薬物の効率的送達) 新規なDDS戦略(ペプチドベクターを用いた動物細胞へのタンパク質・薬物の効率的送達) 関西地区3学協会合同大会シンポジウム 最先端バイオテクノロジーとその展開 関西地区3学協会合同大会シンポジウム 最先端バイオテクノロジーとその展開 吹田 吹田 2005/11/11 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドの発見と研究の展開 膜透過ペプチドの発見と研究の展開 第7回ペプチドフォーラム 膜透過ペプチド:細胞との相互作用と蛋白質・薬物デリバリーへの応用 第7回ペプチドフォーラム 膜透過ペプチド:細胞との相互作用と蛋白質・薬物デリバリーへの応用 京都 京都 2005/08/04 Japanese Oral presentation(invited, special) Disclose to all
細胞膜と相互作用するペプチドと細胞内デリバリー 細胞膜と相互作用するペプチドと細胞内デリバリー 立命館大学大学院理工学研究科応用化学系特殊講義「光と生命」 立命館大学大学院理工学研究科応用化学系特殊講義「光と生命」 草津 草津 2005/05/13 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いたタンパク質・薬物の細胞内デリバリー アルギニンペプチドを用いたタンパク質・薬物の細胞内デリバリー 日本化学会生体機能関連化学部会講習会 「細胞の機能を観て調べて利用する」 日本化学会生体機能関連化学部会講習会 「細胞の機能を観て調べて利用する」 仙台 仙台 2004/10/29 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドとのハイブリッド化によるタンパク質・薬物の効率的細胞内導入 塩基性ペプチドとのハイブリッド化によるタンパク質・薬物の効率的細胞内導入 第19回バイオハイブリッド研究会 第19回バイオハイブリッド研究会 横浜 横浜 2004/05/24 Japanese Oral presentation(invited, special) Disclose to all
細胞膜と相互作用するアルギニンペプチド 細胞膜と相互作用するアルギニンペプチド 電気学会第71回大会 電気学会第71回大会 横浜 横浜 2004/03/24 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドの膜透過と細胞内デリバリー アルギニンペプチドの膜透過と細胞内デリバリー 日本薬学会関東支部学術講演会「バイオマテリアルと薬学の接点」 日本薬学会関東支部学術講演会「バイオマテリアルと薬学の接点」 横浜 横浜 2003/12/08 Japanese Oral presentation(invited, special) Disclose to all
細胞内移送ツールとしてのペプチド 細胞内移送ツールとしてのペプチド 第4回ペプチドフォーラム (日本ペプチド学会?かずさDNA研究所ジョイントフォーラム) ?ゲノム科学とペプチド科学の相互発展のためにー 第4回ペプチドフォーラム (日本ペプチド学会?かずさDNA研究所ジョイントフォーラム) ?ゲノム科学とペプチド科学の相互発展のためにー 木更津 木更津 2003/10/28 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドを用いたタンパク質・薬物の細胞内導入 膜透過ペプチドを用いたタンパク質・薬物の細胞内導入 有機合成夏期セミナー:明日の有機合成化学 有機合成夏期セミナー:明日の有機合成化学 大阪 大阪 2003/09/12 Japanese Oral presentation(invited, special) Disclose to all
新規細胞膜透過ペプチドの設計と評価 新規細胞膜透過ペプチドの設計と評価 第56回新適塾「21世紀の薬箱」 新しい治療戦略「細胞内への機能性蛋白質の送達システムと疾病治療への展望」 第56回新適塾「21世紀の薬箱」 新しい治療戦略「細胞内への機能性蛋白質の送達システムと疾病治療への展望」 千里 千里 2003/09/09 Japanese Oral presentation(invited, special) Disclose to all
膜・細胞を標的とする機能性ペプチドの設計と展開 膜・細胞を標的とする機能性ペプチドの設計と展開 日本薬学会東海支部講演会(名古屋市立大学薬学研究科大学院講義) 日本薬学会東海支部講演会(名古屋市立大学薬学研究科大学院講義) 名古屋 名古屋 2003/07/02 Japanese Oral presentation(invited, special) Disclose to all
細胞膜を効率的に透過するアルギニンペプチド 細胞膜を効率的に透過するアルギニンペプチド 理化学研究所生体超分子フォーラム 理化学研究所生体超分子フォーラム 和光 和光 2003/06/26 Japanese Oral presentation(invited, special) Disclose to all
細胞へのテーラーメイド物質移送 細胞へのテーラーメイド物質移送 日本化学会第83春季年会特別企画 「テーラーメイド生命化学」 日本化学会第83春季年会特別企画 「テーラーメイド生命化学」 東京 東京 2003/03/18 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドによる機能性分子の細胞内導入 アルギニンペプチドによる機能性分子の細胞内導入 日本薬学会第123年会 ミニシンポジウム「薬学における生命志向型化学」 日本薬学会第123年会 ミニシンポジウム「薬学における生命志向型化学」 長崎 長崎 2003/03/02 Japanese Oral presentation(invited, special) Disclose to all
ナノ分子の細胞内機能化に向けた効率的導入系の開発 ナノ分子の細胞内機能化に向けた効率的導入系の開発 北海道大学21世紀COE(バイオとナノを融合する新生命科学拠点)シンポジウム 「バイオとナノの融合を目指して」 北海道大学21世紀COE(バイオとナノを融合する新生命科学拠点)シンポジウム 「バイオとナノの融合を目指して」 札幌 札幌 2003/02/20 Japanese Oral presentation(invited, special) Disclose to all
バイオメディカルツールとしての細胞導入ペプチド バイオメディカルツールとしての細胞導入ペプチド 第3回ペプチドフォーラム ペプチド・ブレインストーミングセミナー(2003、札幌) ?バイオメディカルツールとしてのペプチドの新しい可能性を求めて? 第3回ペプチドフォーラム ペプチド・ブレインストーミングセミナー(2003、札幌) ?バイオメディカルツールとしてのペプチドの新しい可能性を求めて? 札幌 札幌 2003/02/01 Japanese Oral presentation(invited, special) Disclose to all
膜透過能を有するアルギニンペプチド複合体のデザイン 膜透過能を有するアルギニンペプチド複合体のデザイン 文部科学省科研費特定領域研究(A) 分子シンクロ材料 ミニシンポジウム 細胞内デリバリーのための分子シンクロナイゼーション 文部科学省科研費特定領域研究(A) 分子シンクロ材料 ミニシンポジウム 細胞内デリバリーのための分子シンクロナイゼーション 吹田 吹田 2002/12/10 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドによる細胞内効率的物質導入 塩基性ペプチドによる細胞内効率的物質導入 ゲノムテクノロジー第164委員会 第11回研究会(ゲノミクス分科会) ゲノムテクノロジー第164委員会 第11回研究会(ゲノミクス分科会) 吹田 吹田 2002/11/28 Japanese Oral presentation(invited, special) Disclose to all
アルギニンペプチドを用いたタンパク質・薬物の効率的細胞内導入 アルギニンペプチドを用いたタンパク質・薬物の効率的細胞内導入 京都大学国際融合創造センター 第9回京滋化学技術交流会プログラム 京都大学国際融合創造センター 第9回京滋化学技術交流会プログラム 京都 京都 2002/11/12 Japanese Oral presentation(invited, special) Disclose to all
膜透過ペプチドによるタンパク質の細胞内効率的導入と細胞機能解明へのポテンシャル 膜透過ペプチドによるタンパク質の細胞内効率的導入と細胞機能解明へのポテンシャル 日本生化学会第75回大会シンポジウム 「生命現象解明を志向したテイラーメイド化学」 日本生化学会第75回大会シンポジウム 「生命現象解明を志向したテイラーメイド化学」 京都 京都 2002/10/15 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドを用いた高分子の効率的細胞内送達 塩基性ペプチドを用いた高分子の効率的細胞内送達 科学技術振興事業団・戦略的創造研究推進事業(CREST)研究領域 『化学・生物系の新材料等の創製』片岡チーム・チームミーティング 科学技術振興事業団・戦略的創造研究推進事業(CREST)研究領域 『化学・生物系の新材料等の創製』片岡チーム・チームミーティング 札幌 札幌 2002/07/27 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドを用いたタンパク質・核酸の効率的細胞内導入 塩基性ペプチドを用いたタンパク質・核酸の効率的細胞内導入 第18回日本DDS学会ワークショップ 「遺伝子デリバリーシステムの進歩」 第18回日本DDS学会ワークショップ 「遺伝子デリバリーシステムの進歩」 札幌 札幌 2002/06/22 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドを用いたタンパク質の効率的細胞内導入65 ?細胞内タンパク質の機能解析へのポテンシャル 塩基性ペプチドを用いたタンパク質の効率的細胞内導入65 ?細胞内タンパク質の機能解析へのポテンシャル 第8回日本生化学会近畿支部テクニカルセミナー「ポストゲノム時代を迎えた遺伝子・タンパク質の機能解析」 第8回日本生化学会近畿支部テクニカルセミナー「ポストゲノム時代を迎えた遺伝子・タンパク質の機能解析」 京都 京都 2002/05/12 Japanese Oral presentation(invited, special) Disclose to all
機能性ペプチドと細胞表層技術 機能性ペプチドと細胞表層技術 近畿バイオインダストリー振興会議勉強会 「細胞表層技術を活用した診断や創薬のためのHTSシステム開発」 近畿バイオインダストリー振興会議勉強会 「細胞表層技術を活用した診断や創薬のためのHTSシステム開発」 大阪 大阪 2002/03/13 Japanese Oral presentation(invited, special) Disclose to all
塩基性ペプチドを用いた細胞内へのタンパク質・薬物のデリバリー 塩基性ペプチドを用いた細胞内へのタンパク質・薬物のデリバリー 関西TLO技術情報クラブ2月例会 関西TLO技術情報クラブ2月例会 京都 京都 2002/02/05 Japanese Oral presentation(invited, special) Disclose to all
新しい細胞内デリバリーペプチドのデザイン 新しい細胞内デリバリーペプチドのデザイン 東北大学未来科学技術共同センター特別講演 東北大学未来科学技術共同センター特別講演 仙台 仙台 2001/11/06 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドによる機能性イオンチャネルの構築 合成ペプチドによる機能性イオンチャネルの構築 第62回応用物理学会学術講演会 シンポジウム「バイオからのナノテクノロジー」?人工超分子の可能性? 第62回応用物理学会学術講演会 シンポジウム「バイオからのナノテクノロジー」?人工超分子の可能性? 豊田 豊田 2001/09/11 Japanese Oral presentation(invited, special) Disclose to all
Arginine-richペプチドを用いた細胞内デリバリー Arginine-richペプチドを用いた細胞内デリバリー 第17回日本DDS学会 ワークショップ「体内動態制御の新展開」 第17回日本DDS学会 ワークショップ「体内動態制御の新展開」 吹田 吹田 2001/07/12 Japanese Oral presentation(invited, special) Disclose to all
細胞膜を透過するarginine-richペプチド 細胞膜を透過するarginine-richペプチド 京都府立医大解剖学第一講座セミナー 京都府立医大解剖学第一講座セミナー 京都 京都 2001/06/26 Japanese Oral presentation(invited, special) Disclose to all
機能性ペプチドイオンチャネルの構築を目指して 機能性ペプチドイオンチャネルの構築を目指して 日本薬学会第121年会 シンポジウム「膜機能分子の設計と薬学領域におけるポテンシャル」 日本薬学会第121年会 シンポジウム「膜機能分子の設計と薬学領域におけるポテンシャル」 札幌 札幌 2001/03/28 Japanese Oral presentation(invited, special) Disclose to all
Arginine-richペプチド:新しい細胞内タンパク質導入キャリアとしての可能性 Arginine-richペプチド:新しい細胞内タンパク質導入キャリアとしての可能性 北海道大学薬学部特別講演会「21世紀のゲノム創薬を語る:細胞選択的なデリバリーから遺伝子発現とその制御まで」 北海道大学薬学部特別講演会「21世紀のゲノム創薬を語る:細胞選択的なデリバリーから遺伝子発現とその制御まで」 札幌 札幌 2001/02/07 Japanese Oral presentation(invited, special) Disclose to all
細胞透過性ペプチドとコンビナトリアルバイオエンジニアリングの接点 細胞透過性ペプチドとコンビナトリアルバイオエンジニアリングの接点 第1回コンビナトリアル・バイオエンジニアリングシンポジウム?新バイオ分子と機能の創出を目指して? 第1回コンビナトリアル・バイオエンジニアリングシンポジウム?新バイオ分子と機能の創出を目指して? 東京 東京 2001/01/25 Japanese Oral presentation(invited, special) Disclose to all
高分子蛋白質の新しい細胞内導入法:Arginine-richペプチドの細胞膜透過と蛋白質細胞内導入キャリアとしての可能性 高分子蛋白質の新しい細胞内導入法:Arginine-richペプチドの細胞膜透過と蛋白質細胞内導入キャリアとしての可能性 徳島大学大学院医学研究科講義・分子酵素センターセミナー 徳島大学大学院医学研究科講義・分子酵素センターセミナー 徳島 徳島 2001/01/22 Japanese Oral presentation(invited, special) Disclose to all
膜・細胞と相互作用する機能性ペプチド 膜・細胞と相互作用する機能性ペプチド 理研シンポジウム「第4回生体分子の化学」 理研シンポジウム「第4回生体分子の化学」 和光 和光 2000/11/30 Japanese Oral presentation(invited, special) Disclose to all
細胞膜を透過するペプチド 細胞膜を透過するペプチド 第14回生体関連インフォーマルセミナー 第14回生体関連インフォーマルセミナー 京都 京都 1999/11/27 Japanese Oral presentation(invited, special) Disclose to all
Extramembrane Control of Transmembrane Peptide Assembly Extramembrane Control of Transmembrane Peptide Assembly A Multidisciplinary Workshop: Self-Assembling Peptide Systems in Biology, Medicine and Engineering A Multidisciplinary Workshop: Self-Assembling Peptide Systems in Biology, Medicine and Engineering Crete Crete 1999/07/01 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドの会合調節とイオンチャンネル機能 合成ペプチドの会合調節とイオンチャンネル機能 98ー1 バイオ・高分子研究会 タンパク質工学の新展開 98ー1 バイオ・高分子研究会 タンパク質工学の新展開 三重 三重 1998/10/03 Japanese Oral presentation(invited, special) Disclose to all
イオンチャネル形成ペプチドの会合調節と機能 イオンチャネル形成ペプチドの会合調節と機能 第13回生体機能関連化学シンポジウム若手フォーラム 第13回生体機能関連化学シンポジウム若手フォーラム 松山 松山 1998/09/13 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドの機能化 合成ペプチドの機能化 第4回島津ライフサイエンスセミナー 第4回島津ライフサイエンスセミナー 大阪 大阪 1998/07/03 Japanese Oral presentation(invited, special) Disclose to all
蛋白質機能解明と機能創出を目指したペプチド合成 蛋白質機能解明と機能創出を目指したペプチド合成 日本薬学会第118年会 日本薬学会第118年会 京都 京都 1998/03/31 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドを用いた蛋白質構造構築法の開発とイオンチャネル機能の創出 合成ペプチドを用いた蛋白質構造構築法の開発とイオンチャネル機能の創出 佐賀大学 佐賀大学 佐賀 佐賀 1998/01/22 Japanese Oral presentation(invited, special) Disclose to all
Alamethicin-Leucine Zipper Hybrid Peptide: Modulation of the Assembly of the Transmembrane Peptide by the Extramembrane Peptide Segment Alamethicin-Leucine Zipper Hybrid Peptide: Modulation of the Assembly of the Transmembrane Peptide by the Extramembrane Peptide Segment 1st Peptide Enginerring Meeting 1st Peptide Enginerring Meeting 池田 池田 1997/12/07 Japanese Oral presentation(invited, special) Disclose to all
アラメチシンロイシンジッパーハイブリッドペプチド:膜外配列の相互作用による膜貫通ペプチドの会合制御 アラメチシンロイシンジッパーハイブリッドペプチド:膜外配列の相互作用による膜貫通ペプチドの会合制御 第9回名古屋コンファレンス 第9回名古屋コンファレンス 名古屋 名古屋 1997/11/01 Japanese Oral presentation(invited, special) Disclose to all
Fmoc固相法を活用した高付加価値ペプチドの合成研究 Fmoc固相法を活用した高付加価値ペプチドの合成研究 第9回日本ペプチド学会総会 第9回日本ペプチド学会総会 東京 東京 1997/10/24 Japanese Oral presentation(invited, special) Disclose to all
ヘリックスペプチドのアセンブリングによるイオンチャネル機能の創出 ヘリックスペプチドのアセンブリングによるイオンチャネル機能の創出 近畿バイオインダストリー振興会議ペプチド工学研究会 近畿バイオインダストリー振興会議ペプチド工学研究会 池田 池田 1997/10/20 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドによるイオンチャネルモデルの構築 合成ペプチドによるイオンチャネルモデルの構築 日本生物物理学会第35回年会 日本生物物理学会第35回年会 京都 京都 1997/10/10 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドを用いた蛋白質構造構築法の開発とそのイオンチャネルモデル構 合成ペプチドを用いた蛋白質構造構築法の開発とそのイオンチャネルモデル構 第2回生物分子化学研究会 第2回生物分子化学研究会 箱根 箱根 1997/01/31 Japanese Oral presentation(invited, special) Disclose to all
蛋白質機能解明を目指したα?ヘリックス蛋白質モデル構築法の開発 蛋白質機能解明を目指したα?ヘリックス蛋白質モデル構築法の開発 大阪大学蛋白質研究所セミナー「生体分子の人工機能化への展望」 大阪大学蛋白質研究所セミナー「生体分子の人工機能化への展望」 吹田 吹田 1995/09/28 Japanese Oral presentation(invited, special) Disclose to all
合成ペプチドによる蛋白質構造の構築 合成ペプチドによる蛋白質構造の構築 京都薬科大学薬品化学特論 京都薬科大学薬品化学特論 京都 京都 1995/05/22 Japanese Oral presentation(invited, special) Disclose to all
機能性蛋白質の創製を目指した人工α?ヘリックス蛋白質構築法の開発 機能性蛋白質の創製を目指した人工α?ヘリックス蛋白質構築法の開発 「バイオ高分子の新展開?ペプチド・蛋白質・核酸の人工的機能化」(日本高分子学会九州支部主催フォーラム) 「バイオ高分子の新展開?ペプチド・蛋白質・核酸の人工的機能化」(日本高分子学会九州支部主催フォーラム) 熊本 熊本 1995/01/19 Japanese Oral presentation(invited, special) Disclose to all
ペプチドユニットのアセンブリングによる蛋白質構造構築の試み ペプチドユニットのアセンブリングによる蛋白質構造構築の試み 第6回生体機能関連化学若手の会サマースクール 第6回生体機能関連化学若手の会サマースクール 鳴門 鳴門 1993/08/03 Japanese Oral presentation(invited, special) Disclose to all
Peptide-based approaches for delivering exogenous molecules into cells[Invited] Peptide-based approaches for delivering exogenous molecules into cells [Invited] International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery" International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery" 2015/07/05 English Oral presentation(invited, special) Disclose to all
Promotion of membrane translocation of cell-penetrating peptide octaarginine by curvature inducing peptide[Invited] Promotion of membrane translocation of cell-penetrating peptide octaarginine by curvature inducing peptide [Invited] Chinese University of Hong Kong, Special lecture Chinese University of Hong Kong, Special lecture 2013/11/27 English Oral presentation(invited, special) Disclose to all
CPP uptake mechanisms, endocytosis, direct membrane translocation[Invited] CPP uptake mechanisms, endocytosis, direct membrane translocation [Invited] A joint FEBS/Biochemical Society Lecture Course Cell-penetrating peptides: design, synthesis and applications A joint FEBS/Biochemical Society Lecture Course Cell-penetrating peptides: design, synthesis and applications 2013/10/07 English Oral presentation(invited, special) Disclose to all
CXCR4 stimulates macropinocytosis CXCR4 stimulates macropinocytosis 5th European Conference on Chemistry for Life Sciences 5th European Conference on Chemistry for Life Sciences 2013/06/12 English Oral presentation(invited, special) Disclose to all
Arginine-rich cell-penetrating peptides and the effects of membrane curvature on their translocation through membranes[Invited] Arginine-rich cell-penetrating peptides and the effects of membrane curvature on their translocation through membranes [Invited] Institut de Pharmacologie Moléculaire et Cellulaire seminar Institut de Pharmacologie Moléculaire et Cellulaire seminar 2013/06/07 English Oral presentation(invited, special) Disclose to all
CXCR4 stumulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV[Invited] CXCR4 stumulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV [Invited] Recent Advance in Life Chemistry Recent Advance in Life Chemistry 2013/04/19 English Oral presentation(invited, special) Disclose to all
Arginine-rich cell-penetrating peptides and their application to intracellular delivery[Invited] Arginine-rich cell-penetrating peptides and their application to intracellular delivery [Invited] The 111th General Meeting of the Korean Chemical Society The 111th General Meeting of the Korean Chemical Society 2013/04/18 English Oral presentation(invited, special) Disclose to all
Peptide tools for controlling and analyzing cell functions Peptide tools for controlling and analyzing cell functions H24年度 筑波大学戦略イニシアティブ(A)「機能物質創製研究拠点」第3回国際シンポジウム 3rd International Symposium on Center for Creation of Functional Materials H24年度 筑波大学戦略イニシアティブ(A)「機能物質創製研究拠点」第3回国際シンポジウム 3rd International Symposium on Center for Creation of Functional Materials つくば つくば 2012/12/10 English Oral presentation(invited, special) Disclose to all
Creation of artificial epidermal growth factor receptor activated by coiled-coil peptides Creation of artificial epidermal growth factor receptor activated by coiled-coil peptides The Sixth Peptide Engineering Meeting The Sixth Peptide Engineering Meeting Atlanta Atlanta 2012/10/02 English Oral presentation(invited, special) Disclose to all
Activation of Biological Systems through an Artificial Receptor System via Dimerization of a Bivalent Leucine-Zipper Ligand Activation of Biological Systems through an Artificial Receptor System via Dimerization of a Bivalent Leucine-Zipper Ligand The 14th Akabori Conference The 14th Akabori Conference ニセコ ニセコ 2012/09/13 English Oral presentation(invited, special) Disclose to all
Peptide tools for drug delivery and chemical biology Peptide tools for drug delivery and chemical biology Chinese University of Hong Kong, Special lecture Chinese University of Hong Kong, Special lecture Hong Kong Hong Kong 2012/06/25 English Oral presentation(invited, special) Disclose to all
Efficient internalization of arginine-rich cell-penetrating peptide through cell membranes Efficient internalization of arginine-rich cell-penetrating peptide through cell membranes Satellite mini-workshop of IACIS 2012 Satellite mini-workshop of IACIS 2012 千葉(千葉科学大学) 千葉(千葉科学大学) 2012/05/12 English Oral presentation(invited, special) Disclose to all
Mechanisms to attain efficient cellular uptake of arginine-rich cell-penetrating peptides Mechanisms to attain efficient cellular uptake of arginine-rich cell-penetrating peptides Peptide Therapeutics Conference 2012 Peptide Therapeutics Conference 2012 Puerto Calero, Lanzarote, Spain Puerto Calero, Lanzarote, Spain 2012/02/16 English Oral presentation(invited, special) Disclose to all
Creation of peptides that can alter their structure and function by external stimuli Creation of peptides that can alter their structure and function by external stimuli Stockholm University, Neurochemistry seminar Stockholm University, Neurochemistry seminar Stockholm Stockholm 2011/12/19 English Oral presentation(invited, special) Disclose to all
DNA Binding Properties of Ligand-Substituted Zinc Finger Proteins DNA Binding Properties of Ligand-Substituted Zinc Finger Proteins 第21回金属の関与する生体関連反応シンポジウム 第21回金属の関与する生体関連反応シンポジウム 千葉(千葉大学) 千葉(千葉大学) 2011/05/30 English Oral presentation(invited, special) Disclose to all
CXCR4 is a receptor that stimulates cellular uptake of the R12 peptide CXCR4 is a receptor that stimulates cellular uptake of the R12 peptide Peptide Vectors and Delivery of Therapeutics Peptide Vectors and Delivery of Therapeutics Tallinn, Estonia Tallinn, Estonia 2011/05/20 English Oral presentation(invited, special) Disclose to all
Cell-penetrating peptides as a tool for intracellular delivery Cell-penetrating peptides as a tool for intracellular delivery 2010環太平洋国際化学会議 Pacifichem2010 Session Title: Molecular Probes and Fluorophores for Cellular Imaging (#157) 2010環太平洋国際化学会議 Pacifichem2010 Session Title: Molecular Probes and Fluorophores for Cellular Imaging (#157) Honolulu, Hawaii, USA Honolulu, Hawaii, USA 2010/12/20 English Oral presentation(invited, special) Disclose to all
Metal switch of peptide structure and function Metal switch of peptide structure and function 2010環太平洋国際化学会議 Pacifichem2010 Session Title: Frontiers in Peptide Chemistry: Synthesis and Applications (#41) 2010環太平洋国際化学会議 Pacifichem2010 Session Title: Frontiers in Peptide Chemistry: Synthesis and Applications (#41) Honolulu, Hawaii, USA Honolulu, Hawaii, USA 2010/12/19 English Oral presentation(invited, special) Disclose to all
Translocation of arginine-rich peptides through biological membranes Translocation of arginine-rich peptides through biological membranes 大阪大学蛋白質研究所セミナー The New Trend of Peptide Science in Asia and Oceania ペプチド科学 ?アジア・オセアニアの新潮流? 大阪大学蛋白質研究所セミナー The New Trend of Peptide Science in Asia and Oceania ペプチド科学 ?アジア・オセアニアの新潮流? 吹田 吹田 2010/12/11 English Oral presentation(invited, special) Disclose to all
Design and Creation of Metal-responsive DNA-binding Proteins Design and Creation of Metal-responsive DNA-binding Proteins 5th International Peptide Symposium in conjugation with 47th Japanese Peptide Symposium 5th International Peptide Symposium in conjugation with 47th Japanese Peptide Symposium Kyoto Kyoto 2010/12/04 English Oral presentation(invited, special) Disclose to all
Peptide-mediated intracellular delivery ? chemical-biology and?drug-delivery aspects Peptide-mediated intracellular delivery ? chemical-biology and?drug-delivery aspects Seminars for the Doctoral School as an Invited Professor Seminars for the Doctoral School as an Invited Professor Universit? Pierre et Marie Curi Paris, France Universit? Pierre et Marie Curi Paris, France 2010/10/14 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: the methods of internalization Arginine-rich peptides: the methods of internalization National Museum of Natural History National Museum of Natural History Paris, France Paris, France 2010/10/08 English Oral presentation(invited, special) Disclose to all
Physiological and physicochemical factors that achieve efficient?internalization of arginine-rich cell-penetrating peptides" Physiological and physicochemical factors that achieve efficient?internalization of arginine-rich cell-penetrating peptides" Seminars for the Doctoral School as an Invited Professor Seminars for the Doctoral School as an Invited Professor Universit? Pierre et Marie Curi Paris, France Universit? Pierre et Marie Curi Paris, France 2010/10/07 English Oral presentation(invited, special) Disclose to all
Design of Functional Switching Peptides Design of Functional Switching Peptides Seminars for the Doctoral School as an Invited Professor Mini-synposium Seminars for the Doctoral School as an Invited Professor Mini-synposium Universit? Pierre et Marie Curi Paris, France Universit? Pierre et Marie Curi Paris, France 2010/10/04 English Oral presentation(invited, special) Disclose to all
Creation of peptides that can alter their structure and function by?the external stimuli Creation of peptides that can alter their structure and function by?the external stimuli Seminars for the Doctoral School as an Invited Professor Seminars for the Doctoral School as an Invited Professor Universit? Pierre et Marie Curi Paris, France Universit? Pierre et Marie Curi Paris, France 2010/09/30 English Oral presentation(invited, special) Disclose to all
Metal Switches of Peptide Functions Metal Switches of Peptide Functions 1st Asian Chemical Biology Conference 1st Asian Chemical Biology Conference Seoul, Korea Seoul, Korea 2010/06/25 English Oral presentation(invited, special) Disclose to all
Chemical and Biological Factors that Stimulate Intracellular Delivery Using Arginine-Rich Cell-Penetrating Peptides Chemical and Biological Factors that Stimulate Intracellular Delivery Using Arginine-Rich Cell-Penetrating Peptides 9th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and the International Workshop on Biomaterials 9th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and the International Workshop on Biomaterials Changshun, China Changshun, China 2010/06/12 English Oral presentation(invited, special) Disclose to all
Cellular dynamics involved in the internalization of arginine-rich cell penetrating peptides Cellular dynamics involved in the internalization of arginine-rich cell penetrating peptides 3rd Asia-Pacific International Peptide Symposium 3rd Asia-Pacific International Peptide Symposium Jeju Island, Korea Jeju Island, Korea 2009/11/10 English Oral presentation(invited, special) Disclose to all
Physiological and non-physiological factors involved in the internalization of arginine-rich peptides Physiological and non-physiological factors involved in the internalization of arginine-rich peptides Fifth Peptide Engineering Meeting (PEM5) Fifth Peptide Engineering Meeting (PEM5) Barcelona, Spain Barcelona, Spain 2009/10/27 English Oral presentation(invited, special) Disclose to all
Creation of Zinc Finger-Based Artificial Transcription Factors Creation of Zinc Finger-Based Artificial Transcription Factors Department Seminar, School of Parmacy, University of Maryland Department Seminar, School of Parmacy, University of Maryland Baltimore, USA Baltimore, USA 2009/09/21 English Oral presentation(invited, special) Disclose to all
Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides PepVec2009 Meeting on "Intracellular Delivery of Therapeutic Molecules: From Bench to Bedside" PepVec2009 Meeting on "Intracellular Delivery of Therapeutic Molecules: From Bench to Bedside" Montpellier, France Montpellier, France 2009/09/01 English Oral presentation(invited, special) Disclose to all
Chemical and biological factors that contribute to the internalization of arginine-rich cell-penetrating peptides Chemical and biological factors that contribute to the internalization of arginine-rich cell-penetrating peptides 第15回日本遺伝子治療学会 第15回日本遺伝子治療学会 Suita Suita 2009/07/09 English Oral presentation(invited, special) Disclose to all
Oligoarginine Vectors for Intracellular Delivery Oligoarginine Vectors for Intracellular Delivery 2009 International Symposium & Annual Meeting of Korean Society for Microbiology and Biotechnology (KMB) 2009 International Symposium & Annual Meeting of Korean Society for Microbiology and Biotechnology (KMB) Daejeon, Korea Daejeon, Korea 2009/06/25 English Oral presentation(invited, special) Disclose to all
Internalization of Arginine-rich Peptides into Cells Internalization of Arginine-rich Peptides into Cells The 6th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on Biomaterials The 6th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on Biomaterials Sanya, China Sanya, China 2008/11/26 English Oral presentation(invited, special) Disclose to all
Accelerated intracellular delivery using arginine-rich peptide vectors Accelerated intracellular delivery using arginine-rich peptide vectors 4th Korea-Japan Workshop on Combinatorial Bioengineering 4th Korea-Japan Workshop on Combinatorial Bioengineering Seoul, Korea Seoul, Korea 2008/11/22 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides as a intracellular delivery vector Arginine-rich peptides as a intracellular delivery vector 12 th Korean Peptide-Protein Society Symposium 12 th Korean Peptide-Protein Society Symposium Seoul, Korea Seoul, Korea 2008/11/21 English Oral presentation(invited, special) Disclose to all
Internalization mechanism of cell penetrating peptides Internalization mechanism of cell penetrating peptides 第34回 化学と生物シンポジウム Unconventional Pathway of Protein Secretion and Internalization: Mystery across Cell Membranes (タンパク質の分泌と細胞内導入の非定型的経路 細胞膜透過のミステリー) 第34回 化学と生物シンポジウム Unconventional Pathway of Protein Secretion and Internalization: Mystery across Cell Membranes (タンパク質の分泌と細胞内導入の非定型的経路 細胞膜透過のミステリー) 名古屋 名古屋 2008/09/27 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides as a vector of intracellular delivery Arginine-rich peptides as a vector of intracellular delivery 3rd International Workshop on Approaches to Single-Cell Analysis 3rd International Workshop on Approaches to Single-Cell Analysis Zurich, Switzerland, Zurich, Switzerland, 2008/09/12 English Oral presentation(invited, special) Disclose to all
Cellular dynamics of cell penetrating peptides Cellular dynamics of cell penetrating peptides 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008" 2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008" Cardiff, UK Cardiff, UK 2008/06/24 English Oral presentation(invited, special) Disclose to all
Controlling channel peptide assembly and gating by extramembrane conformational switch Controlling channel peptide assembly and gating by extramembrane conformational switch Japanese-Swiss Symposium on Chemical Biology (JSCB) Japanese-Swiss Symposium on Chemical Biology (JSCB) Lausanne, Switzerland Lausanne, Switzerland 2007/06/25 English Oral presentation(invited, special) Disclose to all
Membrane interaction and internalization of arginine-rich peptides Membrane interaction and internalization of arginine-rich peptides Stockholm University Neurochemistry Seminar Stockholm University Neurochemistry Seminar Stockholm, Sweden Stockholm, Sweden 2007/05/23 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides and their internalization mechanisms Arginine-rich peptides and their internalization mechanisms Biochemical Society Focused Meeting Cell Penetrating Peptides Biochemical Society Focused Meeting Cell Penetrating Peptides Telford, UK Telford, UK 2007/05/10 English Oral presentation(invited, special) Disclose to all
Cell penetrating peptides and their internalization mechanisms Cell penetrating peptides and their internalization mechanisms Special Lecture at Welsh School of Pharmacy Special Lecture at Welsh School of Pharmacy Cardiff, UK Cardiff, UK 2007/05/08 English Oral presentation(invited, special) Disclose to all
Artificial ion channels gating by extramembrane conformation switch Artificial ion channels gating by extramembrane conformation switch Japan-Italy Research Cooperative Program: Japan-Italy Symposium of New Trends in Enzyme Science and Technology Japan-Italy Research Cooperative Program: Japan-Italy Symposium of New Trends in Enzyme Science and Technology Nagoya Nagoya 2006/11/16 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides and the internalization mechanisms Arginine-rich peptides and the internalization mechanisms International Mini Symposium “Membrane-permeable peptides: Chemistry, biology and therapeutic applications” (The 9th Peptide Forum; A satellite meeting of International Conference of 43rd Japanese Peptide Symposium/ 4th Peptide Engineering Meeting) International Mini Symposium “Membrane-permeable peptides: Chemistry, biology and therapeutic applications” (The 9th Peptide Forum; A satellite meeting of International Conference of 43rd Japanese Peptide Symposium/ 4th Peptide Engineering Meeting) Kyoto Kyoto 2006/11/10 English Oral presentation(invited, special) Disclose to all
Transmission of Extramembrane Conformational Switch into Channel Current; Design and Construction of Artificial Metal-gated Receptor Channel Transmission of Extramembrane Conformational Switch into Channel Current; Design and Construction of Artificial Metal-gated Receptor Channel International conference of 43rd Japanese Peptide Symposum/4th Peptide Engineering Meeting 第43回ペプチド討論会/第4回ペプチド工学国際会議 International conference of 43rd Japanese Peptide Symposum/4th Peptide Engineering Meeting 第43回ペプチド討論会/第4回ペプチド工学国際会議 Yokohama Yokohama 2006/11/05 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides as a deliver vector Arginine-rich peptides as a deliver vector The 11th Akabori Conference 2006 Japanese-German Symposium on Peptide Science The 11th Akabori Conference 2006 Japanese-German Symposium on Peptide Science Kloseter Banz, Germany Kloseter Banz, Germany 2006/09/10 English Oral presentation(invited, special) Disclose to all
Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms The first FIP-APSTJ joint workshop on gene delivery The first FIP-APSTJ joint workshop on gene delivery Sapporo Sapporo 2006/07/11 English Oral presentation(invited, special) Disclose to all
Membrane-permeable arginine-rich peptides and the interaction with cell membranes Membrane-permeable arginine-rich peptides and the interaction with cell membranes 10th Naples Workshop on Bioactive Peptides 10th Naples Workshop on Bioactive Peptides Naples, Italy Naples, Italy 2006/06/13 English Oral presentation(invited, special) Disclose to all
Peptide vectors for intracellular delivery Peptide vectors for intracellular delivery 日本学術振興会 第2回日独先端科学(JGFos)シンポジウム2005 2nd Annual symposium Japanese-German Frontiers of Sciences 日本学術振興会 第2回日独先端科学(JGFos)シンポジウム2005 2nd Annual symposium Japanese-German Frontiers of Sciences 逗子 逗子 2005/11/04 English Oral presentation(invited, special) Disclose to all
Membrane-permeable arginine-rich peptides and the translocation mechanisms Membrane-permeable arginine-rich peptides and the translocation mechanisms Wenner-Gren Foundations international symposium “Cell-penetrating peptides and applications” Wenner-Gren Foundations international symposium “Cell-penetrating peptides and applications” Stockholm, Sweden Stockholm, Sweden 2005/05/19 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: aspects of membrane translocation Arginine-rich peptides: aspects of membrane translocation Delivery of macromolecules into cells using non-viral vectors Delivery of macromolecules into cells using non-viral vectors Toronto, Canada Toronto, Canada 2004/07/10 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: mechanistic aspects of cellular uptake Arginine-rich peptides: mechanistic aspects of cellular uptake 第6回ファーマサイエンスフォーラム 第6回ファーマサイエンスフォーラム 札幌 札幌 2004/05/08 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: aspects of translocation Arginine-rich peptides: aspects of translocation Stockholm University, Dpt. Neurochemistry and Neurotoxicology講演会 Stockholm University, Dpt. Neurochemistry and Neurotoxicology講演会 Stockholm, Sweden Stockholm, Sweden 2003/11/17 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: the aspects of membrane translocation Arginine-rich peptides: the aspects of membrane translocation Cellular Drug Transport Mechanisms Workshop Cellular Drug Transport Mechanisms Workshop M?lndal, Sweden M?lndal, Sweden 2003/11/14 English Oral presentation(invited, special) Disclose to all
Peptide-Based Ion-Channels as Prototypes for the Artificial Receptors and Sensors Peptide-Based Ion-Channels as Prototypes for the Artificial Receptors and Sensors 21世紀COE 京都大学化学連携教育拠点 講演会 生物無機関連化学シンポジウム Symposium on Biological Inorganic and Related Chemistry 21世紀COE 京都大学化学連携教育拠点 講演会 生物無機関連化学シンポジウム Symposium on Biological Inorganic and Related Chemistry 京都 京都 2003/08/11 English Oral presentation(invited, special) Disclose to all
Potential of arginine-rich peptides as carriers for intracellular protein delivery Potential of arginine-rich peptides as carriers for intracellular protein delivery 3rd Peptide Engineering Meeting (PEM-III) 3rd Peptide Engineering Meeting (PEM-III) Boston Boston 2003/07/17 English Oral presentation(invited, special) Disclose to all
Translocation of Various Arginine-rich Peptides through the Cell Membranes: Potential of These Peptides as Carriers for Intracellular Protein Delivery Translocation of Various Arginine-rich Peptides through the Cell Membranes: Potential of These Peptides as Carriers for Intracellular Protein Delivery 21 世紀COE「京都大学化学連携研究教育拠点」交流事業プログラム 韓国KAIST(Korea Advanced Institute of Science and Technology)?京都大学大学院理学研究科化学専攻連携研究拠点学術交流シンポジウム 現代分子科学の進展 Recent progress of advanced molecular science 21 世紀COE「京都大学化学連携研究教育拠点」交流事業プログラム 韓国KAIST(Korea Advanced Institute of Science and Technology)?京都大学大学院理学研究科化学専攻連携研究拠点学術交流シンポジウム 現代分子科学の進展 Recent progress of advanced molecular science 京都 京都 2003/02/19 English Oral presentation(invited, special) Disclose to all
Arginine-rich peptides: Potential of these peptides as carriers for intracellular delivery of bioactive molecules Arginine-rich peptides: Potential of these peptides as carriers for intracellular delivery of bioactive molecules Cellular transport strategies for targeting of epitopes, drugs and reporter molecules (CellTarget) workshop Cellular transport strategies for targeting of epitopes, drugs and reporter molecules (CellTarget) workshop Budapest Budapest 2003/02/06 English Oral presentation(invited, special) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
中瀬生彦、田中弦、二木史朗 中瀬生彦、田中弦、二木史朗 最新ペプチド合成技術とその創薬研究への応用 木曽良明編集(向井秀仁編集協力) 最新ペプチド合成技術とその創薬研究への応用 木曽良明編集(向井秀仁編集協力) 遺伝子医学MOOK21, 第5章2, 173-178 遺伝子医学MOOK21, 第5章2, 173-178 2012 Japanese Disclose to all
髙山健太郎、二木史朗、林良雄、山本昌 髙山健太郎、二木史朗、林良雄、山本昌 自己分解型リンカーを用いたオリゴアルギニン修飾による薬物の消化管吸収の改善 自己分解型リンカーを用いたオリゴアルギニン修飾による薬物の消化管吸収の改善 難吸収性薬物の吸収改善と新規投与製剤の開発, 第3章5, 119-125 難吸収性薬物の吸収改善と新規投与製剤の開発, 第3章5, 119-125 2012 Japanese Disclose to all
二木史朗,中瀬生彦 二木史朗,中瀬生彦 ペプチドベクターを用いた効率的細胞導入法 ペプチドベクターを用いた効率的細胞導入法 蛍光イメージング/MRI プローブの開発 菊地和也監修, 第19章, 173-179 蛍光イメージング/MRI プローブの開発 菊地和也監修, 第19章, 173-179 2011 Japanese Disclose to all
二木史朗(分担) 二木史朗(分担) 医薬品各条 医薬品各条 第十六改正日本薬局方解説書, , 第十六改正日本薬局方解説書, , 2011 Japanese Disclose to all
二木史朗,中瀬生彦 二木史朗,中瀬生彦 オリゴアルギニン修飾を用いた薬物の細胞内取込の改善とその機構 オリゴアルギニン修飾を用いた薬物の細胞内取込の改善とその機構 遺伝子医学MOOK別冊 ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用 山本昌編集, 第2章5, 117-122 遺伝子医学MOOK別冊 ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用 山本昌編集, 第2章5, 117-122 2010 Japanese Disclose to all
浜地 格、二木史朗編 浜地 格、二木史朗編 化学フロンティア 生命現象を理解する分子ツール:イメージングから生体機能解析まで 第14章ペプチドをツールとして用いた細胞内への物質輸送 化学フロンティア 生命現象を理解する分子ツール:イメージングから生体機能解析まで 第14章ペプチドをツールとして用いた細胞内への物質輸送 化学同人, , 111-118 化学同人, , 111-118 2010 Japanese Disclose to all
二木史朗 二木史朗 13膜透過ペプチド 13膜透過ペプチド 機能性DDSキャリアの製材設計 岡田弘晃監修 シーエムシー出版 第2章DDSキャリア素材の基本設計, , 142-149 機能性DDSキャリアの製材設計 岡田弘晃監修 シーエムシー出版 第2章DDSキャリア素材の基本設計, , 142-149 2008 Japanese Disclose to all
二木史朗(分担) 二木史朗(分担) 医薬品各条 医薬品各条 第十五改正日本薬局方解説書 廣川書店, , 第十五改正日本薬局方解説書 廣川書店, , 2006 Japanese Disclose to all
二木史朗 二木史朗 第4章4.細胞内導入 第4章4.細胞内導入 遺伝子医学MOOK5 先端生物医学研究・医療のための遺伝子導入テクノロジー ウイルスを用いない遺伝子導入法の材料、技術、方法論の新たな展開 原島秀吉、田畑泰彦編集 メディカルドゥ, , 202-206 遺伝子医学MOOK5 先端生物医学研究・医療のための遺伝子導入テクノロジー ウイルスを用いない遺伝子導入法の材料、技術、方法論の新たな展開 原島秀吉、田畑泰彦編集 メディカルドゥ, , 202-206 2006 Japanese Disclose to all
二木史朗 二木史朗 第27章 薬物送達への展開 第27章 薬物送達への展開 化学フロンティア9 コンビナトリアルバイオエンジニアリング情報から機能の創出をめざして 植田充美, 近藤昭彦編 化学同人 , , 189-193 化学フロンティア9 コンビナトリアルバイオエンジニアリング情報から機能の創出をめざして 植田充美, 近藤昭彦編 化学同人 , , 189-193 2003 Japanese Disclose to all
武山正治, 伊藤信行, 二木史朗 武山正治, 伊藤信行, 二木史朗 廣川タンパク質化学 第11巻 ホルモン系タンパク質およびポリアミンII 北川幸己, 五十嵐一衛編集 廣川書店 廣川タンパク質化学 第11巻 ホルモン系タンパク質およびポリアミンII 北川幸己, 五十嵐一衛編集 廣川書店 , 第9章 消化管ホルモン前駆体, 181- , 第9章 消化管ホルモン前駆体, 181- 1996 Japanese Disclose to all
北川幸己, 二木史朗 北川幸己, 二木史朗 続医薬品の開発 第14巻 ペプチド合成 矢島治明監修 岡田芳男, 木曽良明編集 廣川書店 続医薬品の開発 第14巻 ペプチド合成 矢島治明監修 岡田芳男, 木曽良明編集 廣川書店 , 第6章 脱保護法, 205-232 , 第6章 脱保護法, 205-232 1991 Japanese Disclose to all
二木史朗 二木史朗 膜透過性アルギニンペプチドの細胞内移行機序と薬物送達 膜透過性アルギニンペプチドの細胞内移行機序と薬物送達 ペプチド医薬の最前線 木曽良明、向井秀仁監修, 第2章9, 74-77 ペプチド医薬の最前線 木曽良明、向井秀仁監修, 第2章9, 74-77 Japanese Disclose to all
NAKASE, Ikuhiko.; KOGURE, Kentaro.; HARASHIMA, Hideyoshi.; FUTAKI, Shiroh. NAKASE, Ikuhiko.; KOGURE, Kentaro.; HARASHIMA, Hideyoshi.; FUTAKI, Shiroh. Chapter 37. Application of a Fusiogenic Peptide GALA for Intracellular Delivery In Cell-Penetrating Peptides: Methods and Protocols Ed. By ?lo Langel Chapter 37. Application of a Fusiogenic Peptide GALA for Intracellular Delivery In Cell-Penetrating Peptides: Methods and Protocols Ed. By ?lo Langel Methods in Molecular Biology, Springer Ed. By ?lo Langel, 683, 525-533 Methods in Molecular Biology, Springer Ed. By ?lo Langel, 683, 525-533 2010 English Disclose to all
Futaki S, Asami K Futaki S, Asami K Ligand-Induced Extramembrane Conformation Switch Controlling Alamethicin Assembly and the Channel Current Ligand-Induced Extramembrane Conformation Switch Controlling Alamethicin Assembly and the Channel Current Peptaibols: Fungal Peptides Containing a-Dialkyl a-Amino Acids, , 344-352 Peptaibols: Fungal Peptides Containing a-Dialkyl a-Amino Acids, , 344-352 2009 English Disclose to all
Kamada M, Maegawa M, Maeda N, Yamamoto S, Yoshikawa S, Mori H, Tanaka Y, Okada M, Shitukawa K, Irahara1 M, Aono T, Kido H, Ogushi F , Sone S, Kanayama N, Kagawa S, Ohmoto Y, Futaki S, Zhi Guo Liang, Samuel S. Koide Kamada M, Maegawa M, Maeda N, Yamamoto S, Yoshikawa S, Mori H, Tanaka Y, Okada M, Shitukawa K, Irahara1 M, Aono T, Kido H, Ogushi F , Sone S, Kanayama N, Kagawa S, Ohmoto Y, Futaki S, Zhi Guo Liang, Samuel S. Koide Immunoglobulin binding factor in human seminal plasma and uterine cerivical mucus Immunoglobulin binding factor in human seminal plasma and uterine cerivical mucus Current Paradigm of Reproductive Immunology, , 95-104 Current Paradigm of Reproductive Immunology, , 95-104 2009 English Disclose to all
Futaki S Futaki S Assembly Modulation of Channel-Forming Peptides Assembly Modulation of Channel-Forming Peptides Self-Assembling Peptide Systems in Biology, Medicine and Engineering , , 87-104 Self-Assembling Peptide Systems in Biology, Medicine and Engineering , , 87-104 2001 English Disclose to all

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Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
平成9年度 日本ペプチド学会奨励賞 The Japanese Peptide Society Award for Young Scientists 日本ペプチド学会 The Japanese Peptide Society 1997/10/24
1997年度 有機合成化学協会 第一製薬研究企画賞 Daiichi Pharmaceutical Award in Synthetic Organic Chemistry, Japan 有機合成化学協会 The Society of Synthetic Organic Chemistry, Japan 1997/12/19
平成10年度 日本薬学会奨励賞 The PSJ (Pharmaceutical Society of Japan) Award for Young Scientists 日本薬学会 The Pharmaceutical Society of Japan 1998/03/31
平成18年度 竹田国際貢献賞 竹田理科工業株式会社 2006/09/15
2011 AAPS Journal Manuscript Award 2011 AAPS Journal Manuscript Award American Association of Pharmaceutical Sciences American Association of Pharmaceutical Sciences 2011/10/23
平成25年度特別研究員等審査会専門委員(書面担当)及び 国際事業委員会書面審査員の表彰 日本学術振興会 JSPS 2014/07/31
ハンガリー科学アカデミー名誉会員 Honorary Member of Hungarian Academy of Sciences ハンガリー科学アカデミー Hungarian Academy of Sciences 2019/05/10
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
基盤(A)一般研究 Representative 膜透過ペプチドの細胞移行のケミカルバイオロジー 2007-
基盤(B)(2) Representative 膜透過ペプチドを用いた新規細胞内修飾剤の開発とタンパク質相互作用解析 2002-
基盤(B)(2) Representative 転写因子の活性化制御を目指した新規合成ペプチドの創製と効率的細胞内導入 2002-
基盤(B)(2) Representative 転写因子の活性化制御を目指した新規合成ペプチドの創製と効率的細胞内導入 2001-
基盤(B)(2) Representative 転写因子の活性化制御を目指した新規合成ペプチドの創製と効率的細胞内導入 2000-
基盤(B)一般研究 Representative 細胞内標的ペプチドベクターの開発と細胞内送達のリアルタイム追跡 2006-
基盤(B)一般研究 Representative 細胞内標的ペプチドベクターの開発と細胞内送達のリアルタイム追跡 2005-
長瀬科学技術振興財団助成 Representative リガンドの相互作用を膜電流として伝える人工受容体型チャネルの創出と展開 2007-
特定 Representative 細胞内可視化・ハイスループット検出系創出のための効率的細胞導入法 2007-
特定 Representative バイオセンサーによる細胞内イメージングのための対イオン送達法の最適化 2006-
特定(A)(2) Representative 膜外シグナルによる膜内ペプチドの会合調節を利用した膜電流制御システムの構築 2001-
特定(A)(2) Representative 膜外シグナルによる膜内ペプチドの会合調節を利用した膜電流制御システムの構築 2000-
特定領域(2) Representative 膜外シグナルによる膜内ペプチドの会合調節を利用した膜電流制御システムの構築 2002-
萌芽 Representative ペプチドマトリクスを使った高分子量タンパク質の細胞内送達 2002-
萌芽 Representative 難溶性薬物のキャリアを目指した新規大環状ヘリックス蚕白質の創出 2001-
挑戦的萌芽研究 Representative 成人T細胞白血病関連タンパク質特異的認識ペプチドライブラリーの設計と選択 2013-2014
新学術領域研究(研究領域提案型) Representative 生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツール 2014-2015
挑戦的萌芽研究 Representative 核酸アプタマーを膜外配列として用いた人工リガンド作動性イオンチャネルの構築 2015-2016
基盤研究(A)(一般) Representative バイオ医薬品の新たな細胞内導入戦略 2015-2017
挑戦的萌芽研究 Representative 成人T細胞白血病関連タンパク質特異的認識ペプチドライブラリーの設計と選択 (平成26年度分) 2014/04/01-2015/03/31
新学術領域研究(研究領域提案型) Representative 生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツール (平成26年度分) 2014/04/01-2015/03/31
基盤研究(A) Representative バイオ高分子医薬品の新たな細胞内導入戦略 (平成27年度分) 2015/04/01-2016/03/31
挑戦的萌芽研究 Representative 核酸アプタマーを膜外配列として用いた人工リガンド作動性イオンチャネルの構築 (平成27年度分) 2015/04/01-2016/03/31
新学術領域研究(研究領域提案型) Representative 生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツール (平成27年度分) 2015/04/01-2016/03/31
挑戦的萌芽研究 Representative 核酸アプタマーを膜外配列として用いた人工リガンド作動性イオンチャネルの構築 (平成28年度分) 2016/04/01-2017/03/31
新学術領域研究(研究領域提案型) Representative 生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツール (平成28年度分) 2016/04/01-2017/03/31
新学術領域研究(研究領域提案型) Representative 生物機能中分子の細胞内への新規導入基盤の創出 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(A) Representative バイオ高分子医薬品の新たな細胞内導入戦略 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(A) Representative バイオ高分子医薬品の新たな細胞内導入戦略 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(A) Representative バイオ高分子医薬品の新たな細胞内導入戦略 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(A) Representative バイオ高分子医薬品の新たな細胞内導入戦略 (平成29年度分) 2017/04/01-2018/03/31
挑戦的萌芽研究 Representative 核酸アプタマーを膜外配列として用いた人工リガンド作動性イオンチャネルの構築 (平成29年度分) 2017/04/01-2018/03/31
新学術領域研究(研究領域提案型) Representative 生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツール (平成29年度分) 2017/04/01-2018/03/31
新学術領域研究(研究領域提案型) Representative 生物機能中分子の細胞内への新規導入基盤の創出 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(A) Representative 生理活性タンパク質の細胞内移送の新機軸 (平成30年度分) 2018/04/01-2019/03/31
新学術領域研究(研究領域提案型) Representative 生体膜の曲率・脂質パッキング状態変化を誘起する機能性ペプチド (平成30年度分) 2018/04/01-2019/03/31
新学術領域研究(研究領域提案型) Representative 生物機能中分子の細胞導入の分子基盤 (平成30年度分) 2018/04/01-2019/03/31

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External funds: other than those above
System Main person Title(Japanese) Title(English) Period
二国間交流事業共同研究・セミナー 二木 史朗 アルブミンを血中保持担体に用いた腫瘍組織への薬物送達の新戦略 (平成27年度分) 2015/04/01-2016/03/31
二国間交流事業共同研究・セミナー 二木 史朗 アルブミンを血中保持担体に用いた腫瘍組織への薬物送達の新戦略 (平成28年度分) 2016/04/01-2017/03/31
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
生体機能化学 後期 薬学部 2011/04-2012/03
特別実習(生体機能化学) 通年 薬学部 2011/04-2012/03
有機化学5(生体機能化学) 後期 薬学部 2011/04-2012/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2011/04-2012/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2011/04-2012/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2011/04-2012/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2011/04-2012/03
基盤生物化学実験技術(秋入学用) Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2011/04-2012/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2011/04-2012/03
有機化学3(創薬化学) 前期 薬学部 2011/04-2012/03
有機化学V(有機合成論) 前期 薬学部 2011/04-2012/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2012/04-2013/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2012/04-2013/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2012/04-2013/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2012/04-2013/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2012/04-2013/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2012/04-2013/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2012/04-2013/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2012/04-2013/03
基盤生物化学特論II Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2012/04-2013/03
有機化学3(創薬化学) Organic Chemistry 3 (Medicinal Chemistry) 前期 薬学部 2012/04-2013/03
有機化学V(有機合成論) Synthetic Organic Chemistry 前期 薬学部 2012/04-2013/03
有機化学5(生体機能化学) Organic Chemistry 5 (Biofunctional Chemistry) 後期 薬学部 2012/04-2013/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2012/04-2013/03
生体機能化学 Biofunctional Chemistry 後期 薬学部 2012/04-2013/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2013/04-2014/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2013/04-2014/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2013/04-2014/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2013/04-2014/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2013/04-2014/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2013/04-2014/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2013/04-2014/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2013/04-2014/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2013/04-2014/03
博士後期課程特論 doctoral program 後期集中 薬学研究科 2013/04-2014/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2014/04-2015/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2014/04-2015/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2014/04-2015/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2014/04-2015/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2014/04-2015/03
基盤生物化学特論II Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2014/04-2015/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2014/04-2015/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2014/04-2015/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2014/04-2015/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2015/04-2016/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2015/04-2016/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2015/04-2016/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2015/04-2016/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2015/04-2016/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2015/04-2016/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2015/04-2016/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2015/04-2016/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 後期前期 薬学研究科 2016/04-2017/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2016/04-2017/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 後期前期 薬学研究科 2016/04-2017/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2016/04-2017/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 後期前期 薬学研究科 2016/04-2017/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2016/04-2017/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2016/04-2017/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2016/04-2017/03
基盤生物化学概論 Introduction to Basic Biological Chemistry 前期不定 薬学研究科 2016/04-2017/03
基盤生物化学特論II Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2016/04-2017/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2016/04-2017/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2016/04-2017/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2017/04-2018/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2017/04-2018/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2017/04-2018/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2017/04-2018/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2017/04-2018/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2017/04-2018/03
基盤生物化学特論I Advanced Basic Biological Chemistry I 前期不定 薬学研究科 2017/04-2018/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2017/04-2018/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2017/04-2018/03
薬学研究概論 Introduction to Pharmaceutical Sciences 前期不定 薬学研究科 2017/04-2018/03
創薬リード探索理論 Bioinformatics II: Lead Discovery 前期不定 薬学研究科 2018/04-2019/03
創薬生命科学概論 Introduction to Modern Life Sciences for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2018/04-2019/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2018/04-2019/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2018/04-2019/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2018/04-2019/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2018/04-2019/03
基盤生物化学特論II Advanced Basic Biological Chemistry II 前期不定 薬学研究科 2018/04-2019/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2018/04-2019/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2018/04-2019/03
基盤生体機能化学実習 Laboratory Practice in Basic Biofunctional Chemistry 通年不定 薬学研究科 2019/04-2020/03
基盤生体機能化学実験 Research in Basic Biofunctional Chemistry 通年不定 薬学研究科 2019/04-2020/03
基盤生体機能化学演習 Basic Biofunctional Chemistry Seminar 通年不定 薬学研究科 2019/04-2020/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 前期不定 薬学研究科 2019/04-2020/03
基盤生物化学実験技術 Basic Laboratory Techniques in Biological Chemistry 後期不定 薬学研究科 2019/04-2020/03
基盤生物化学特論I Advanced Basic Biological Chemistry I 前期不定 薬学研究科 2019/04-2020/03
特別実習(生体機能化学) Research Training(Biofunctional Chemistry) 通年 薬学部 2019/04-2020/03
生物化学IV(応用生物分子科学) Biological Chemistry IV (Applied biomolecular science) 前期 薬学部 2019/04-2020/03
生物化学4(応用生物分子科学) Biological Chemistry 4 (Applied biomolecular science) 前期 薬学部 2019/04-2020/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2019/04-2020/03

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Part-time lecturer (outside KU)
Cource name(Japanese) Cource name(English) Term University Department Period
甲南大学 2019/04/01-2020/03/31
School management (title, position)
Title Period
放射性同位元素等管理委員会 委員 2008/04/01-2011/03/31
大学評価委員会 点検・評価実行委員会 委員 2010/04/01-
大学評価委員会点検・評価実行委員会 委員 2011/04/01-2012/03/31
大学評価委員会 点検・評価実行委員会 委員 2012/04/01-2013/03/31
教育制度委員会 委員 2012/04/01-2013/03/31
教育制度委員会WG2 委員 2012/04/01-2013/03/31
設備整備・共用促進委員会 委員 2018/04/01-2020/03/31
Faculty management (title, position)
Title Period
化学研究所ゲノムネット推進室運営委員会委員 2011/04/01-2014/03/31
放射性同位元素等専門委員会委員 2011/04/01-2013/03/31
環境安全保健機構保健専門委員会委員 2011/04/01-2013/03/31
学際融合教育研究推進センター生存基盤科学研究ユニット連携推進委員 2011/04/01-2013/03/31
化学研究所運営委員会委員 2012/04/01-2014/03/31
化学研究所建物管理委員会委員 2012/04/01-2014/03/31
化学研究所財務委員会委員 2012/04/01-2014/03/31
化学研究所自己点検評価委員会委員 2012/04/01-2014/03/31
化学研究所総務・教務委員会委員 2012/04/01-2014/03/31
化学研究所副所長 2012/04/01-2014/03/31
宇治地区共通施設運営委員会委員 2013/01/01-2014/12/31
化学研究所情報セキュリティ委員会委員 2013/04/01-2014/03/31
化学研究所人権委員会委員 2013/04/01-2014/03/31
環境安全保健機構保健専門委員会委員 2013/04/01-2015/03/31
放射性同位元素等専門委員会委員 2013/04/01-2015/03/31
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