山下 富義

Last Update: 2019/10/29 09:38:04

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Name(Kanji/Kana/Abecedarium Latinum)
山下 富義/ヤマシタ フミヨシ/Yamashita, Fumiyoshi
Primary Affiliation(Org1/Job title)
Graduate Schools Pharmaceutical Sciences/Professor
Faculty
Org1 Job title
薬学部
Academic Organizations You are Affiliated to in Japan
Organization name(Japanese) Organization name(English)
日本薬学会 The Pharmaceutical Society of Japan
日本薬物動態学会 The Japanese Society for the Study of Xenobiotics
日本薬剤学会 The Academy of Pharmaceutical Sciences and Technology, Japan
日本DDS学会 The Japan Society of Drug Delivery System
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
薬学修士 京都大学
博士(薬学) 京都大学
Personal Profile
(Japanese)
薬物の体内動態の予測および制御に関する研究を行っている。教育に関しては、薬剤学に関する講義・演習の他、薬剤師養成に向けた演習および臨床実務実習のコーディネートも担当している。製薬企業等との共同研究を積極的に行い、学術成果を医薬品開発に活かしている。
(English)
My research interests are prediction and control of drug disposition behaviors in the body. As for education, I am in charge of lecture and practice on pharmaceutics. I am also responsible for arranging clinical clerkship on pharmaceutical care for students.
Language of Instruction
Language
English
ORCID ID
https://orcid.org/0000-0002-3503-8696
researchmap URL
https://researchmap.jp/read0013274
Research Topics
(Japanese)
薬物体内動態の予測と制御、ドラッグデリバリ―システムの開発
(English)
Prediction and control of drug disposition behaviors in body, development of drug delivery systems
Overview of the research
(Japanese)
薬物動態は投与された薬物の薬効や毒性を決定する重要な因子である。計算科学的な方法を駆使して薬物の体内動態を予測する方法論の開発、ナノ材料を用いて薬物動態を制御する技術の開発を通じて、薬物療法の最適化に資することを目的としている。
(English)
Pharmacokinetics of a drug is a critical determinant of its pharmacological and toxicological activities. Aiming at optimization of therapeutic efficacy of drugs, I am developing nanomedicines that can control pharmacokinetic behaviors in the body, as well as prediction of pharmacokinetic properties by using informatic and computational techniques.
Fields of research (key words)
Key words(Japanese) Key words(English)
薬剤学;薬物動態学;DDS Pharmaceutics; Pharmacokinetics; Drug Delivery System
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Ota R, Ishii H, Tsuda M, Higuchi Y, Yamashita F Ota R, Ishii H, Tsuda M, Higuchi Y, Yamashita F Ota R, Ishii H, Tsuda M, Higuchi Y, Yamashita F A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients. A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients. A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2019/04 Refereed Disclose to all
Feng C, Zhang H, Chen J, Wang S, Xin Y, Qu Y, Zhang Q, Ji W, Yamashita F, Rui M, Xu X Feng C, Zhang H, Chen J, Wang S, Xin Y, Qu Y, Zhang Q, Ji W, Yamashita F, Rui M, Xu X Feng C, Zhang H, Chen J, Wang S, Xin Y, Qu Y, Zhang Q, Ji W, Yamashita F, Rui M, Xu X Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. International journal of pharmaceutics, 560, 191-204 International journal of pharmaceutics, 560, 191-204 International journal of pharmaceutics, 560, 191-204 2019/04 Refereed Disclose to all
Rahimova N, Babazada H, Higuchi Y, Yamashita F, Hashida M Rahimova N, Babazada H, Higuchi Y, Yamashita F, Hashida M Rahimova N, Babazada H, Higuchi Y, Yamashita F, Hashida M Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells. Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells. Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells. Biochimica et biophysica acta. Molecular cell research, 1866, 2, 190-198 Biochimica et biophysica acta. Molecular cell research, 1866, 2, 190-198 Biochimica et biophysica acta. Molecular cell research, 1866, 2, 190-198 2019/02 Refereed Disclose to all
Babazada H, Yanamoto S, Hashida M, Yamashita F Babazada H, Yanamoto S, Hashida M, Yamashita F Babazada H, Yanamoto S, Hashida M, Yamashita F Binding and structure-kinetic relationship analysis of selective TLR4-targeted immunosuppressive self-assembling heparin nanoparticles. Binding and structure-kinetic relationship analysis of selective TLR4-targeted immunosuppressive self-assembling heparin nanoparticles. Binding and structure-kinetic relationship analysis of selective TLR4-targeted immunosuppressive self-assembling heparin nanoparticles. International journal of pharmaceutics, 552, 1-2, 76-83 International journal of pharmaceutics, 552, 1-2, 76-83 International journal of pharmaceutics, 552, 1-2, 76-83 2018/12 Refereed Disclose to all
Matsumura K, Zouda M, Wada Y, Yamashita F, Hashida M, Watanabe Y, Mukai H Matsumura K, Zouda M, Wada Y, Yamashita F, Hashida M, Watanabe Y, Mukai H Matsumura K, Zouda M, Wada Y, Yamashita F, Hashida M, Watanabe Y, Mukai H Urokinase injection-triggered clearance enhancement of a 4-arm PEG-conjugated <sup>64</sup>Cu-bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast. Urokinase injection-triggered clearance enhancement of a 4-arm PEG-conjugated <sup>64</sup>Cu-bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast. Urokinase injection-triggered clearance enhancement of a 4-arm PEG-conjugated <sup>64</sup>Cu-bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast. International journal of pharmaceutics, 545, 1-2, 206-214 International journal of pharmaceutics, 545, 1-2, 206-214 International journal of pharmaceutics, 545, 1-2, 206-214 2018/07 Refereed Disclose to all
Yamashita F, Fujita A, Sasa Y, Higuchi Y, Tsuda M, Hashida M Yamashita F, Fujita A, Sasa Y, Higuchi Y, Tsuda M, Hashida M Yamashita F, Fujita A, Sasa Y, Higuchi Y, Tsuda M, Hashida M An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis. An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis. An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis. Journal of pharmaceutical sciences, 106, 9, 2407-2411 Journal of pharmaceutical sciences, 106, 9, 2407-2411 Journal of pharmaceutical sciences, 106, 9, 2407-2411 2017/09 Refereed Disclose to all
Chantarasrivong C, Ueki A, Ohyama R, Unga J, Nakamura S, Nakanishi I, Higuchi Y, Kawakami S, Ando H, Imamura A, Ishida H, Yamashita F, Kiso M, Hashida M Chantarasrivong C, Ueki A, Ohyama R, Unga J, Nakamura S, Nakanishi I, Higuchi Y, Kawakami S, Ando H, Imamura A, Ishida H, Yamashita F, Kiso M, Hashida M Chantarasrivong C, Ueki A, Ohyama R, Unga J, Nakamura S, Nakanishi I, Higuchi Y, Kawakami S, Ando H, Imamura A, Ishida H, Yamashita F, Kiso M, Hashida M Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells. Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells. Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells. Molecular pharmaceutics, 14, 5, 1528-1537 Molecular pharmaceutics, 14, 5, 1528-1537 Molecular pharmaceutics, 14, 5, 1528-1537 2017/05 Refereed Disclose to all
Baba H, Ueno Y, Hashida M, Yamashita F Baba H, Ueno Y, Hashida M, Yamashita F Baba H, Ueno Y, Hashida M, Yamashita F Quantitative prediction of ionization effect on human skin permeability. Quantitative prediction of ionization effect on human skin permeability. Quantitative prediction of ionization effect on human skin permeability. International journal of pharmaceutics, 522, 1-2, 222-233 International journal of pharmaceutics, 522, 1-2, 222-233 International journal of pharmaceutics, 522, 1-2, 222-233 2017/04 Refereed Disclose to all
Ohta T, Hashida Y, Higuchi Y, Yamashita F, Hashida M Ohta T, Hashida Y, Higuchi Y, Yamashita F, Hashida M Ohta T, Hashida Y, Higuchi Y, Yamashita F, Hashida M In Vitro Cellular Gene Delivery Employing a Novel Composite Material of Single-Walled Carbon Nanotubes Associated With Designed Peptides With Pegylation. In Vitro Cellular Gene Delivery Employing a Novel Composite Material of Single-Walled Carbon Nanotubes Associated With Designed Peptides With Pegylation. In Vitro Cellular Gene Delivery Employing a Novel Composite Material of Single-Walled Carbon Nanotubes Associated With Designed Peptides With Pegylation. Journal of pharmaceutical sciences, 106, 3, 792-802 Journal of pharmaceutical sciences, 106, 3, 792-802 Journal of pharmaceutical sciences, 106, 3, 792-802 2017/03 Refereed Disclose to all
Yanamoto S, Babazada H, Sakai S, Higuchi Y, Yamashita F, Hashida M Yanamoto S, Babazada H, Sakai S, Higuchi Y, Yamashita F, Hashida M Yanamoto S, Babazada H, Sakai S, Higuchi Y, Yamashita F, Hashida M Anti-inflammatory Effect of Self-assembling Glycol-Split Glycosaminoglycan-Stearylamine Conjugates in Lipopolysaccharide-Stimulated Macrophages. Anti-inflammatory Effect of Self-assembling Glycol-Split Glycosaminoglycan-Stearylamine Conjugates in Lipopolysaccharide-Stimulated Macrophages. Anti-inflammatory Effect of Self-assembling Glycol-Split Glycosaminoglycan-Stearylamine Conjugates in Lipopolysaccharide-Stimulated Macrophages. Biological & pharmaceutical bulletin, 40, 4, 540-545 Biological & pharmaceutical bulletin, 40, 4, 540-545 Biological & pharmaceutical bulletin, 40, 4, 540-545 2017 Refereed Disclose to all
Morishita Y, Yoshioka Y, Takimura Y, Shimizu Y, Namba Y, Nojiri N, Ishizaka T, Takao K, Yamashita F, Takuma K, Ago Y, Nagano K, Mukai Y, Kamada H, Tsunoda S, Saito S, Matsuda T, Hashida M, Miyakawa T, Higashisaka K, Tsutsumi Y Morishita Y, Yoshioka Y, Takimura Y, Shimizu Y, Namba Y, Nojiri N, Ishizaka T, Takao K, Yamashita F, Takuma K, Ago Y, Nagano K, Mukai Y, Kamada H, Tsunoda S, Saito S, Matsuda T, Hashida M, Miyakawa T, Higashisaka K, Tsutsumi Y Morishita Y, Yoshioka Y, Takimura Y, Shimizu Y, Namba Y, Nojiri N, Ishizaka T, Takao K, Yamashita F, Takuma K, Ago Y, Nagano K, Mukai Y, Kamada H, Tsunoda S, Saito S, Matsuda T, Hashida M, Miyakawa T, Higashisaka K, Tsutsumi Y Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice. Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice. Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice. ACS nano, 10, 9, 8180-8191 ACS nano, 10, 9, 8180-8191 ACS nano, 10, 9, 8180-8191 2016/09 Refereed Disclose to all
Ohta T, Hashida Y, Yamashita F, Hashida M Ohta T, Hashida Y, Yamashita F, Hashida M Ohta T, Hashida Y, Yamashita F, Hashida M Development of Novel Drug and Gene Delivery Carriers Composed of Single-Walled Carbon Nanotubes and Designed Peptides With PEGylation. Development of Novel Drug and Gene Delivery Carriers Composed of Single-Walled Carbon Nanotubes and Designed Peptides With PEGylation. Development of Novel Drug and Gene Delivery Carriers Composed of Single-Walled Carbon Nanotubes and Designed Peptides With PEGylation. Journal of pharmaceutical sciences, 105, 9, 2815-2824 Journal of pharmaceutical sciences, 105, 9, 2815-2824 Journal of pharmaceutical sciences, 105, 9, 2815-2824 2016/09 Refereed Disclose to all
Katsumi H, Nishikawa M, Hirosaki R, Okuda T, Kawakami S, Yamashita F, Hashida M, Sakane T, Yamamoto A Katsumi H, Nishikawa M, Hirosaki R, Okuda T, Kawakami S, Yamashita F, Hashida M, Sakane T, Yamamoto A Katsumi H, Nishikawa M, Hirosaki R, Okuda T, Kawakami S, Yamashita F, Hashida M, Sakane T, Yamamoto A Development of PEGylated Cysteine-Modified Lysine Dendrimers with Multiple Reduced Thiols To Prevent Hepatic Ischemia/Reperfusion Injury. Development of PEGylated Cysteine-Modified Lysine Dendrimers with Multiple Reduced Thiols To Prevent Hepatic Ischemia/Reperfusion Injury. Development of PEGylated Cysteine-Modified Lysine Dendrimers with Multiple Reduced Thiols To Prevent Hepatic Ischemia/Reperfusion Injury. Molecular pharmaceutics, 13, 8, 2867-2873 Molecular pharmaceutics, 13, 8, 2867-2873 Molecular pharmaceutics, 13, 8, 2867-2873 2016/08 Refereed Disclose to all
Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure. Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure. Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure. Journal of pharmaceutical sciences, 105, 7, 2222-2230 Journal of pharmaceutical sciences, 105, 7, 2222-2230 Journal of pharmaceutical sciences, 105, 7, 2222-2230 2016/07 Refereed Disclose to all
Yamashita F Yamashita F Yamashita F Modeling and simulation of pharmacokinetic drug-drug interaction caused by induction of metabolic enzymes. Modeling and simulation of pharmacokinetic drug-drug interaction caused by induction of metabolic enzymes. Modeling and simulation of pharmacokinetic drug-drug interaction caused by induction of metabolic enzymes. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 147, 2, 95-100 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 147, 2, 95-100 Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 147, 2, 95-100 2016/02 Refereed Disclose to all
Masuda M, Kawakami S, Wijagkanalan W, Suga T, Fuchigami Y, Yamashita F, Hashida M Masuda M, Kawakami S, Wijagkanalan W, Suga T, Fuchigami Y, Yamashita F, Hashida M Masuda M, Kawakami S, Wijagkanalan W, Suga T, Fuchigami Y, Yamashita F, Hashida M Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells. Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells. Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells. Biological & pharmaceutical bulletin, 39, 10, 1734-1738 Biological & pharmaceutical bulletin, 39, 10, 1734-1738 Biological & pharmaceutical bulletin, 39, 10, 1734-1738 2016 Refereed Disclose to all
Ohta T, Hashida Y, Yamashita F, Hashida M Ohta T, Hashida Y, Yamashita F, Hashida M Ohta T, Hashida Y, Yamashita F, Hashida M Sustained Release of Mitomycin C from Its Conjugate with Single-Walled Carbon Nanotubes Associated by Pegylated Peptide. Sustained Release of Mitomycin C from Its Conjugate with Single-Walled Carbon Nanotubes Associated by Pegylated Peptide. Sustained Release of Mitomycin C from Its Conjugate with Single-Walled Carbon Nanotubes Associated by Pegylated Peptide. Biological & pharmaceutical bulletin, 39, 10, 1687-1693 Biological & pharmaceutical bulletin, 39, 10, 1687-1693 Biological & pharmaceutical bulletin, 39, 10, 1687-1693 2016 Refereed Disclose to all
Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M Optimization of renal transfection using a renal suction-mediated transfection method in mice. Optimization of renal transfection using a renal suction-mediated transfection method in mice. Optimization of renal transfection using a renal suction-mediated transfection method in mice. Journal of drug targeting, 24, 5, 450-456 Journal of drug targeting, 24, 5, 450-456 Journal of drug targeting, 24, 5, 450-456 2016 Refereed Disclose to all
Baba H, Takahara JI, Yamashita F, Hashida M Baba H, Takahara JI, Yamashita F, Hashida M Baba H, Takahara JI, Yamashita F, Hashida M Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest. Pharmaceutical research, 32, 11, 3604-3617 Pharmaceutical research, 32, 11, 3604-3617 Pharmaceutical research, 32, 11, 3604-3617 2015/06 Refereed Disclose to all
Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. International journal of pharmaceutics, 487, 1-2, 64-71 International journal of pharmaceutics, 487, 1-2, 64-71 International journal of pharmaceutics, 487, 1-2, 64-71 2015/06 Refereed Disclose to all
Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Acta biomaterialia, 19, 112-118 Acta biomaterialia, 19, 112-118 Acta biomaterialia, 19, 112-118 2015/06 Refereed Disclose to all
Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. Journal of drug targeting, 23, 5, 427-435 Journal of drug targeting, 23, 5, 427-435 Journal of drug targeting, 23, 5, 427-435 2015/06 Refereed Disclose to all
Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. The Journal of toxicological sciences, 40, 2, 277-294 The Journal of toxicological sciences, 40, 2, 277-294 The Journal of toxicological sciences, 40, 2, 277-294 2015/04 Refereed Disclose to all
Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Carbohydrate research, 405, 78-86 Carbohydrate research, 405, 78-86 Carbohydrate research, 405, 78-86 2015/03 Refereed Disclose to all
Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, Yamashita F, Uchida T, Ogihara T Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, Yamashita F, Uchida T, Ogihara T Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, Yamashita F, Uchida T, Ogihara T Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. Journal of pharmaceutical sciences, 104, 9, 2789-2794 Journal of pharmaceutical sciences, 104, 9, 2789-2794 Journal of pharmaceutical sciences, 104, 9, 2789-2794 2014/12 Refereed Disclose to all
Babazada H, Yamashita F, Hashida M Babazada H, Yamashita F, Hashida M Babazada H, Yamashita F, Hashida M Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 Journal of controlled release : official journal of the Controlled Release Society, 194, 295-300 2014/11 Refereed Disclose to all
Babazada H, Yamashita F, Yanamoto S, Hashida M Babazada H, Yamashita F, Yanamoto S, Hashida M Babazada H, Yamashita F, Yanamoto S, Hashida M Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 Journal of controlled release : official journal of the Controlled Release Society, 194, 332-340 2014/11 Refereed Disclose to all
Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. International journal of pharmaceutics, 475, 1, 401-407 International journal of pharmaceutics, 475, 1, 401-407 International journal of pharmaceutics, 475, 1, 401-407 2014/11 Refereed Disclose to all
Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 Nanomedicine : nanotechnology, biology, and medicine, 10, 8, 1829-1838 2014/11 Refereed Disclose to all
Nakanishi H, Higuchi Y, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Yamashita F, Hashida M Nakanishi H, Higuchi Y, Yamashita F, Hashida M Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. Journal of biotechnology, 186, 139-147 Journal of biotechnology, 186, 139-147 Journal of biotechnology, 186, 139-147 2014/09 Refereed Disclose to all
Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Journal of drug targeting, 22, 8, 732-738 Journal of drug targeting, 22, 8, 732-738 Journal of drug targeting, 22, 8, 732-738 2014/09 Refereed Disclose to all
Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. International journal of pharmaceutics, 471, 1-2, 214-223 International journal of pharmaceutics, 471, 1-2, 214-223 International journal of pharmaceutics, 471, 1-2, 214-223 2014/08 Refereed Disclose to all
Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Antitumor effect of nuclear factor-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Antitumor effect of nuclear factor-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Antitumor effect of nuclear factor-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Cancer science, 105, 8, 1049-1055 Cancer science, 105, 8, 1049-1055 Cancer science, 105, 8, 1049-1055 2014/08 Refereed Disclose to all
Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. Journal of drug targeting, 22, 5, 439-449 Journal of drug targeting, 22, 5, 439-449 Journal of drug targeting, 22, 5, 439-449 2014/06 Refereed Disclose to all
H. Katsumi; M. Nishikawa; K. Nishiyama; R. Hirosaki; N. Nagamine; H. Okamoto; H. Mizuguchi; K. Kusamori; H. Yasui; F. Yamashita; M. Hashida; T. Sakane; A. Yamamoto Katsumi H, Nishikawa M, Nishiyama K, Hirosaki R, Nagamine N, Okamoto H, Mizuguchi H, Kusamori K, Yasui H, Yamashita F, Hashida M, Sakane T, Yamamoto A H. Katsumi; M. Nishikawa; K. Nishiyama; R. Hirosaki; N. Nagamine; H. Okamoto; H. Mizuguchi; K. Kusamori; H. Yasui; F. Yamashita; M. Hashida; T. Sakane; A. Yamamoto Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice. Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice Free Radical Biology and Medicine, 69, 318-323 Free radical biology & medicine, 69, 318-323 Free Radical Biology and Medicine, 69, 318-323 2014/04 Refereed English Disclose to all
T. Kurosaki; S. Kawakami; Y. Higuchi; R. Suzuki; K. Maruyama; H. Sasaki; F. Yamashita; M. Hashida Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M T. Kurosaki; S. Kawakami; Y. Higuchi; R. Suzuki; K. Maruyama; H. Sasaki; F. Yamashita; M. Hashida Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice. Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice Journal of Controlled Release, 176, 24-34 Journal of controlled release : official journal of the Controlled Release Society, 176, 24-34 Journal of Controlled Release, 176, 24-34 2014/02 Refereed English Disclose to all
P. Buchwald; F. Yamashita Buchwald P, Yamashita F P. Buchwald; F. Yamashita Bilinear model for the size-dependency of the CYP3A4 inhibitory activity of structurally diverse compounds Bilinear Model for the Size-Dependency of the CYP3A4 Inhibitory Activity of Structurally Diverse Compounds. Bilinear model for the size-dependency of the CYP3A4 inhibitory activity of structurally diverse compounds Molecular Informatics, 33, 1, 8-14 Molecular informatics, 33, 1, 8-14 Molecular Informatics, 33, 1, 8-14 2014/01 Refereed English Disclose to all
Y. Hashida; H. Tanaka; S. Zhou; S. Kawakami; F. Yamashita; T. Murakami; T. Umeyama; H. Imahori; M. Hashida Hashida Y, Tanaka H, Zhou S, Kawakami S, Yamashita F, Murakami T, Umeyama T, Imahori H, Hashida M Y. Hashida; H. Tanaka; S. Zhou; S. Kawakami; F. Yamashita; T. Murakami; T. Umeyama; H. Imahori; M. Hashida Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite. Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite Journal of Controlled Release, 173, 59-66 Journal of controlled release : official journal of the Controlled Release Society, 173, 59-66 Journal of Controlled Release, 173, 59-66 2014/01 Refereed English Disclose to all
Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Biological & pharmaceutical bulletin, 37, 4, 648-653 Biological & pharmaceutical bulletin, 37, 4, 648-653 Biological & pharmaceutical bulletin, 37, 4, 648-653 2014 Refereed Disclose to all
Y. Kono; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M Y. Kono; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida In vitro evaluation of inhibitory effect of nuclear factor-kappab activity by small interfering RNA on pro-tumor characteristics of m2-like macrophages In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. In vitro evaluation of inhibitory effect of nuclear factor-kappab activity by small interfering RNA on pro-tumor characteristics of m2-like macrophages Biological and Pharmaceutical Bulletin, 37, 1, 137-144 Biological & pharmaceutical bulletin, 37, 1, 137-144 Biological and Pharmaceutical Bulletin, 37, 1, 137-144 2014 Refereed English Disclose to all
S. Yoshida; F. Yamashita; A. Ose; K. Maeda; Y. Sugiyama; M. Hashida Yoshida S, Yamashita F, Ose A, Maeda K, Sugiyama Y, Hashida M S. Yoshida; F. Yamashita; A. Ose; K. Maeda; Y. Sugiyama; M. Hashida Automated extraction of information on chemical-P-glycoprotein interactions from the literature Automated extraction of information on chemical-P-glycoprotein interactions from the literature. Automated extraction of information on chemical-P-glycoprotein interactions from the literature Journal of Chemical Information and Modeling, 53, 10, 2506-2510 Journal of chemical information and modeling, 53, 10, 2506-2510 Journal of Chemical Information and Modeling, 53, 10, 2506-2510 2013/10 Refereed English Disclose to all
M. Ikemura; M. Nishikawa; K. Kusamori; M. Fukuoka; F. Yamashita; M. Hashida Ikemura M, Nishikawa M, Kusamori K, Fukuoka M, Yamashita F, Hashida M M. Ikemura; M. Nishikawa; K. Kusamori; M. Fukuoka; F. Yamashita; M. Hashida Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice. Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice Journal of Controlled Release, 170, 2, 191-197 Journal of controlled release : official journal of the Controlled Release Society, 170, 2, 191-197 Journal of Controlled Release, 170, 2, 191-197 2013/09 Refereed English Disclose to all
F. Yamashita; M. Hashida Yamashita F, Hashida M F. Yamashita; M. Hashida Pharmacokinetic considerations for targeted drug delivery Pharmacokinetic considerations for targeted drug delivery. Pharmacokinetic considerations for targeted drug delivery Advanced Drug Delivery Reviews, 65, 1, 139-147 Advanced drug delivery reviews, 65, 1, 139-147 Advanced Drug Delivery Reviews, 65, 1, 139-147 2013/01 Refereed English Disclose to all
Y. Takafuji; Y. Higuchi; A. Muro; K. Oshiro; S. Kawakami; F. Yamashita; M. Hashida Takafuji Y, Higuchi Y, Muro A, Oshiro K, Kawakami S, Yamashita F, Hashida M Y. Takafuji; Y. Higuchi; A. Muro; K. Oshiro; S. Kawakami; F. Yamashita; M. Hashida Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids. Factors influencing the surface modification of mesenchymal stem cells with fluorescein-pegylated lipids Biological and Pharmaceutical Bulletin, 36, 11, 1731-1738 Biological & pharmaceutical bulletin, 36, 11, 1731-1738 Biological and Pharmaceutical Bulletin, 36, 11, 1731-1738 2013 Refereed English Disclose to all
F. Yamashita; Y. Sasa; S. Yoshida; A. Hisaka; Y. Asai; H. Kitano; M. Hashida; H. Suzuki Yamashita F, Sasa Y, Yoshida S, Hisaka A, Asai Y, Kitano H, Hashida M, Suzuki H F. Yamashita; Y. Sasa; S. Yoshida; A. Hisaka; Y. Asai; H. Kitano; M. Hashida; H. Suzuki Modeling of Rifampicin-Induced CYP3A4 Activation Dynamics for the Prediction of Clinical Drug-Drug Interactions from In Vitro Data Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data. Modeling of Rifampicin-Induced CYP3A4 Activation Dynamics for the Prediction of Clinical Drug-Drug Interactions from In Vitro Data PLoS ONE, 8, 9, e70330 PloS one, 8, 9, e70330 PLoS ONE, 8, 9, e70330 2013 Refereed English Disclose to all
T. Miyoshi; M. Ito; T. Kitayama; S. Isomori; F. Yamashita Miyoshi T, Ito M, Kitayama T, Isomori S, Yamashita F T. Miyoshi; M. Ito; T. Kitayama; S. Isomori; F. Yamashita Sedative effects of inhaled benzylacetone and structural features contributing to its activity Sedative effects of inhaled benzylacetone and structural features contributing to its activity. Sedative effects of inhaled benzylacetone and structural features contributing to its activity Biological and Pharmaceutical Bulletin, 36, 9, 1474-1481 Biological & pharmaceutical bulletin, 36, 9, 1474-1481 Biological and Pharmaceutical Bulletin, 36, 9, 1474-1481 2013 Refereed English Disclose to all
S. Wada; T. Kano; S. Mita; Y. Idota; K. Morimoto; Y. Fumiyoshi; O. Takuo Wada S, Kano T, Mita S, Idota Y, Morimoto K, Yamashita F, Ogihara T S. Wada; T. Kano; S. Mita; Y. Idota; K. Morimoto; Y. Fumiyoshi; O. Takuo The role of inter-segmental differences in P-glycoprotein expression and activity along the rat small intestine in causing the double-peak phenomenon of substrate plasma concentration The role of inter-segmental differences in P-glycoprotein expression and activity along the rat small intestine in causing the double-peak phenomenon of substrate plasma concentration. The role of inter-segmental differences in P-glycoprotein expression and activity along the rat small intestine in causing the double-peak phenomenon of substrate plasma concentration Drug Metabolism and Pharmacokinetics, 28, 2, 98-103 Drug metabolism and pharmacokinetics, 28, 2, 98-103 Drug Metabolism and Pharmacokinetics, 28, 2, 98-103 2013 Refereed English Disclose to all
S. Yoshida; F. Yamashita; T. Itoh; M. Hashida Yoshida S, Yamashita F, Itoh T, Hashida M S. Yoshida; F. Yamashita; T. Itoh; M. Hashida Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning. Structure-activity relationship modeling for predicting interactions with pregnane X receptor by recursive partitioning Drug Metabolism and Pharmacokinetics, 27, 5, 506-512 Drug metabolism and pharmacokinetics, 27, 5, 506-512 Drug Metabolism and Pharmacokinetics, 27, 5, 506-512 2012/10/25 Refereed English Disclose to all
Y. Umemoto; S. Kawakami; Y. Otani; Y. Higuchi; F. Yamashita; M. Hashida Umemoto Y, Kawakami S, Otani Y, Higuchi Y, Yamashita F, Hashida M Y. Umemoto; S. Kawakami; Y. Otani; Y. Higuchi; F. Yamashita; M. Hashida Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection. Evaluation of long-term gene expression in mouse liver using PhiC31 integrase and hydrodynamic injection Biological and Pharmaceutical Bulletin, 35, 7, 1182-1186 Biological & pharmaceutical bulletin, 35, 7, 1182-1186 Biological and Pharmaceutical Bulletin, 35, 7, 1182-1186 2012/07 Refereed English Disclose to all
M. Tsukamoto; T. Okuda; H. Okamoto; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Tsukamoto M, Okuda T, Okamoto H, Higuchi Y, Kawakami S, Yamashita F, Hashida M M. Tsukamoto; T. Okuda; H. Okamoto; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method. Bovine serum albumin as a lyoprotectant for preparation of DNA dry powder formulations using the spray-freeze drying method Biological and Pharmaceutical Bulletin, 35, 7, 1178-1181 Biological & pharmaceutical bulletin, 35, 7, 1178-1181 Biological and Pharmaceutical Bulletin, 35, 7, 1178-1181 2012/07 Refereed English Disclose to all
K. Un; S. Kawakami; M. Yoshida; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; M. Yoshida; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation. Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation Hepatology, 56, 1, 259-269 Hepatology (Baltimore, Md.), 56, 1, 259-269 Hepatology, 56, 1, 259-269 2012/07 Refereed English Disclose to all
F. Yamashita; A. Fujita; X. Zhang; Y. Sasa; K. Mihara; M. Hashida Yamashita F, Fujita A, Zhang X, Sasa Y, Mihara K, Hashida M F. Yamashita; A. Fujita; X. Zhang; Y. Sasa; K. Mihara; M. Hashida Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations. Computer-based evolutionary search for a nonlinear conversion function for establishing in vitro-in vivo correlation (IVIVC) of oral drug formulations Drug Metabolism and Pharmacokinetics, 27, 3, 280-285 Drug metabolism and pharmacokinetics, 27, 3, 280-285 Drug Metabolism and Pharmacokinetics, 27, 3, 280-285 2012/06/25 Refereed English Disclose to all
Y. Zheng; M. Nishikawa; M. Ikemura; F. Yamashita; M. Hashida Zheng Y, Nishikawa M, Ikemura M, Yamashita F, Hashida M Y. Zheng; M. Nishikawa; M. Ikemura; F. Yamashita; M. Hashida Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice. Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice Journal of Pharmaceutical Sciences, 101, 2, 552-557 Journal of pharmaceutical sciences, 101, 2, 552-557 Journal of Pharmaceutical Sciences, 101, 2, 552-557 2012/02 Refereed English Disclose to all
S. Zhou; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Zhou S, Kawakami S, Higuchi Y, Yamashita F, Hashida M S. Zhou; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice. The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice Clinical and Experimental Metastasis, 29, 1, 63-70 Clinical & experimental metastasis, 29, 1, 63-70 Clinical and Experimental Metastasis, 29, 1, 63-70 2012/01 Refereed English Disclose to all
K.-L. Chang; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M K.-L. Chang; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells. Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells Journal of Controlled Release, 156, 2, 195-202 Journal of controlled release : official journal of the Controlled Release Society, 156, 2, 195-202 Journal of Controlled Release, 156, 2, 195-202 2011/12 Refereed English Disclose to all
K. Un; S. Kawakami; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure. Involvement of activated transcriptional process in efficient gene transfection using unmodified and mannose-modified bubble lipoplexes with ultrasound exposure Journal of Controlled Release, 156, 3, 355-363 Journal of controlled release : official journal of the Controlled Release Society, 156, 3, 355-363 Journal of Controlled Release, 156, 3, 355-363 2011/12 Refereed English Disclose to all
Y. Higuchi; C. Wu; K.-L. Chang; K. Irie; S. Kawakami; F. Yamashita; M. Hashida Higuchi Y, Wu C, Chang KL, Irie K, Kawakami S, Yamashita F, Hashida M Y. Higuchi; C. Wu; K.-L. Chang; K. Irie; S. Kawakami; F. Yamashita; M. Hashida Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells. Polyamidoamine dendrimer-conjugated quantum dots for efficient labeling of primary cultured mesenchymal stem cells Biomaterials, 32, 28, 6676-6682 Biomaterials, 32, 28, 6676-6682 Biomaterials, 32, 28, 6676-6682 2011/10 Refereed English Disclose to all
H. Nakanishi; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M H. Nakanishi; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells. Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells Journal of Biotechnology, 154, 4, 205-208 Journal of biotechnology, 154, 4, 205-208 Journal of Biotechnology, 154, 4, 205-208 2011/07 Refereed English Disclose to all
K. Un; S. Kawakami; M. Yoshida; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Yoshida M, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; M. Yoshida; Y. Higuchi; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes. The elucidation of gene transferring mechanism by ultrasound-responsive unmodified and mannose-modified lipoplexes Biomaterials, 32, 20, 4659-4669 Biomaterials, 32, 20, 4659-4669 Biomaterials, 32, 20, 4659-4669 2011/07 Refereed English Disclose to all
T.D. Dinh; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Dinh TD, Higuchi Y, Kawakami S, Yamashita F, Hashida M T.D. Dinh; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of Pro-inflammatory cytokine production from primary cultured macrophages Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of pro-inflammatory cytokine production from primary cultured macrophages. Evaluation of osteoclastogenesis via NFκB decoy/mannosylated cationic liposome-mediated inhibition of Pro-inflammatory cytokine production from primary cultured macrophages Pharmaceutical Research, 28, 4, 742-751 Pharmaceutical research, 28, 4, 742-751 Pharmaceutical Research, 28, 4, 742-751 2011/04 Refereed English Disclose to all
K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier Molecular Pharmaceutics, 8, 2, 543-554 Molecular pharmaceutics, 8, 2, 543-554 Molecular Pharmaceutics, 8, 2, 543-554 2011/04 Refereed English Disclose to all
F. Yamashita; C. Feng; S. Yoshida; T. Itoh; M. Hashida Yamashita F, Feng C, Yoshida S, Itoh T, Hashida M F. Yamashita; C. Feng; S. Yoshida; T. Itoh; M. Hashida Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates. Automated information extraction and structure-activity relationship analysis of cytochrome P450 substrates Journal of Chemical Information and Modeling, 51, 2, 378-385 Journal of chemical information and modeling, 51, 2, 378-385 Journal of Chemical Information and Modeling, 51, 2, 378-385 2011/02 Refereed English Disclose to all
W. Wijagkanalan; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Wijagkanalan W, Kawakami S, Higuchi Y, Yamashita F, Hashida M W. Wijagkanalan; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation. Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation Journal of Controlled Release, 149, 1, 42-50 Journal of controlled release : official journal of the Controlled Release Society, 149, 1, 42-50 Journal of Controlled Release, 149, 1, 42-50 2011/01 Refereed English Disclose to all
X.-M. Xu; Y.-S. Wang; R.-Y. Chen; C.-L. Feng; F. Yao; S.-S. Tong; L. Wang; F. Yamashita; J.-N. Yu Xu XM, Wang YS, Chen RY, Feng CL, Yao F, Tong SS, Wang L, Yamashita F, Yu JN X.-M. Xu; Y.-S. Wang; R.-Y. Chen; C.-L. Feng; F. Yao; S.-S. Tong; L. Wang; F. Yamashita; J.-N. Yu Formulation and pharmacokinetic evaluation of tetracycline-loaded solid lipid nanoparticles for subcutaneous injection in mice Formulation and pharmacokinetic evaluation of tetracycline-loaded solid lipid nanoparticles for subcutaneous injection in mice. Formulation and pharmacokinetic evaluation of tetracycline-loaded solid lipid nanoparticles for subcutaneous injection in mice Chemical and Pharmaceutical Bulletin, 59, 2, 260-265 Chemical & pharmaceutical bulletin, 59, 2, 260-265 Chemical and Pharmaceutical Bulletin, 59, 2, 260-265 2011 Refereed English Disclose to all
M. Ikemura; M. Nishikawa; K. Hyoudou; Y. Kobayashi; F. Yamashita; M. Hashida Ikemura M, Nishikawa M, Hyoudou K, Kobayashi Y, Yamashita F, Hashida M M. Ikemura; M. Nishikawa; K. Hyoudou; Y. Kobayashi; F. Yamashita; M. Hashida Improvement of insulin resistance by removal of systemic hydrogen peroxide by pegylated catalase in obese mice Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice. Improvement of insulin resistance by removal of systemic hydrogen peroxide by pegylated catalase in obese mice Molecular Pharmaceutics, 7, 6, 2069-2076 Molecular pharmaceutics, 7, 6, 2069-2076 Molecular Pharmaceutics, 7, 6, 2069-2076 2010/12 Refereed English Disclose to all
K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy. Development of an ultrasound-responsive and mannose-modified gene carrier for DNA vaccine therapy Biomaterials, 31, 30, 7813-7826 Biomaterials, 31, 30, 7813-7826 Biomaterials, 31, 30, 7813-7826 2010/10 Refereed English Disclose to all
H. Mukai; S. Kawakami; H. Takahashi; K. Satake; F. Yamashita; M. Hashida Mukai H, Kawakami S, Takahashi H, Satake K, Yamashita F, Hashida M H. Mukai; S. Kawakami; H. Takahashi; K. Satake; F. Yamashita; M. Hashida Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice. Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice Biological and Pharmaceutical Bulletin, 33, 9, 1627-1632 Biological & pharmaceutical bulletin, 33, 9, 1627-1632 Biological and Pharmaceutical Bulletin, 33, 9, 1627-1632 2010/09 Refereed English Disclose to all
T. Miyano; W. Wijagkanalan; S. Kawakami; F. Yamashita; M. Hashida Miyano T, Wijagkanalan W, Kawakami S, Yamashita F, Hashida M T. Miyano; W. Wijagkanalan; S. Kawakami; F. Yamashita; M. Hashida Anionic amino acid dendrimer-\\'trastuzumab conjugates for specific internalization in HER2-positive cancer cells Anionic amino acid dendrimer-trastuzumab conjugates for specific internalization in HER2-positive cancer cells. Anionic amino acid dendrimer-\\'trastuzumab conjugates for specific internalization in HER2-positive cancer cells Molecular Pharmaceutics, 7, 4, 1318-1327 Molecular pharmaceutics, 7, 4, 1318-1327 Molecular Pharmaceutics, 7, 4, 1318-1327 2010/08 Refereed English Disclose to all
K.-L. Chang; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M K.-L. Chang; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape Bioconjugate Chemistry, 21, 6, 1087-1095 Bioconjugate chemistry, 21, 6, 1087-1095 Bioconjugate Chemistry, 21, 6, 1087-1095 2010/06 Refereed English Disclose to all
H. Nakanishi; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M H. Nakanishi; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida PiggyBac transposon-mediated long-term gene expression in mice piggyBac transposon-mediated long-term gene expression in mice. PiggyBac transposon-mediated long-term gene expression in mice Molecular Therapy, 18, 4, 707-714 Molecular therapy : the journal of the American Society of Gene Therapy, 18, 4, 707-714 Molecular Therapy, 18, 4, 707-714 2010/04 Refereed English Disclose to all
K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Un K, Kawakami S, Suzuki R, Maruyama K, Yamashita F, Hashida M K. Un; S. Kawakami; R. Suzuki; K. Maruyama; F. Yamashita; M. Hashida Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure. Enhanced transfection efficiency into macrophages and dendritic cells by a combination method using mannosylated lipoplexes and bubble liposomes with ultrasound exposure Human Gene Therapy, 21, 1, 65-74 Human gene therapy, 21, 1, 65-74 Human Gene Therapy, 21, 1, 65-74 2010/01 Refereed English Disclose to all
S. Zhou; S. Kawakami; F. Yamashita; M. Hashida Zhou S, Kawakami S, Yamashita F, Hashida M S. Zhou; S. Kawakami; F. Yamashita; M. Hashida Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice. Intranasal administration of CpG DNA lipoplex prevents pulmonary metastasis in mice Cancer Letters, 287, 1, 75-81 Cancer letters, 287, 1, 75-81 Cancer Letters, 287, 1, 75-81 2010/01 Refereed English Disclose to all
Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M H. Nakanishi; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M [Development and therapeutic application of transposon-based vectors]. Development and therapeutic application of transposon-based vectors [Development and therapeutic application of transposon-based vectors]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129, 12, 1433-1443 Yakugaku Zasshi, 129, 12, 1433-1443 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129, 12, 1433-1443 2009/12 Refereed Japanese Disclose to all
H. Katsumi; M. Nishikawa; H. Yasui; F. Yamashita; M. Hashida Katsumi H, Nishikawa M, Yasui H, Yamashita F, Hashida M H. Katsumi; M. Nishikawa; H. Yasui; F. Yamashita; M. Hashida Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice. Prevention of ischemia/reperfusion injury by hepatic targeting of nitric oxide in mice Journal of Controlled Release, 140, 1, 12-17 Journal of controlled release : official journal of the Controlled Release Society, 140, 1, 12-17 Journal of Controlled Release, 140, 1, 12-17 2009/11 Refereed English Disclose to all
H. Mukai; S. Kawakami; Y. Kamiya; F. Ma; H. Takahashi; K. Satake; K. Terao; H. Kotera; F. Yamashita; M. Hashida Mukai H, Kawakami S, Kamiya Y, Ma F, Takahashi H, Satake K, Terao K, Kotera H, Yamashita F, Hashida M H. Mukai; S. Kawakami; Y. Kamiya; F. Ma; H. Takahashi; K. Satake; K. Terao; H. Kotera; F. Yamashita; M. Hashida Pressure-mediated transfection of murine spleen and liver. Pressure-mediated transfection of murine spleen and liver. Pressure-mediated transfection of murine spleen and liver. Human gene therapy, 20, 10, 1157-1167 Human gene therapy, 20, 10, 1157-1167 Human gene therapy, 20, 10, 1157-1167 2009/10 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; M. Ikemura; Y. Kobayashi; A. Mendelsohn; N. Miyazaki; Y. Tabata; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; M. Ikemura; Y. Kobayashi; A. Mendelsohn; N. Miyazaki; Y. Tabata; F. Yamashita; M. Hashida Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase. Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase Journal of Controlled Release, 137, 2, 110-115 Journal of controlled release : official journal of the Controlled Release Society, 137, 2, 110-115 Journal of Controlled Release, 137, 2, 110-115 2009/07 Refereed English Disclose to all
T. Okuda; S. Kawakami; Y. Higuchi; T. Satoh; Y. Oka; M. Yokoyama; F. Yamashita; M. Hashida Okuda T, Kawakami S, Higuchi Y, Satoh T, Oka Y, Yokoyama M, Yamashita F, Hashida M T. Okuda; S. Kawakami; Y. Higuchi; T. Satoh; Y. Oka; M. Yokoyama; F. Yamashita; M. Hashida Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles. Enhanced in vivo antitumor efficacy of fenretinide encapsulated in polymeric micelles International Journal of Pharmaceutics, 373, 1-2, 100-106 International journal of pharmaceutics, 373, 1-2, 100-106 International Journal of Pharmaceutics, 373, 1-2, 100-106 2009/05 Refereed English Disclose to all
Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice. Mannosylated cationic liposomes/CpG DNA complex for the treatment of hepatic metastasis after intravenous administration in mice Journal of Pharmaceutical Sciences, 98, 3, 1193-1197 Journal of pharmaceutical sciences, 98, 3, 1193-1197 Journal of Pharmaceutical Sciences, 98, 3, 1193-1197 2009/03 Refereed English Disclose to all
Y. Saito; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Saito Y, Higuchi Y, Kawakami S, Yamashita F, Hashida M Y. Saito; Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Immunostimulatory characteristics induced by linear polyethyleneimine- plasmid DNA complexes in cultured macrophages Immunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages. Immunostimulatory characteristics induced by linear polyethyleneimine- plasmid DNA complexes in cultured macrophages Human Gene Therapy, 20, 2, 137-145 Human gene therapy, 20, 2, 137-145 Human Gene Therapy, 20, 2, 137-145 2009/02 Refereed English Disclose to all
Y. Shiose; H. Kuga; H. Ohki; M. Ikeda; F. Yamashita; M. Hashida Shiose Y, Kuga H, Ohki H, Ikeda M, Yamashita F, Hashida M Y. Shiose; H. Kuga; H. Ohki; M. Ikeda; F. Yamashita; M. Hashida Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates. Systematic research of peptide spacers controlling drug release from macromolecular prodrug system, carboxymethyldextran polyalcohol-peptide-drug conjugates Bioconjugate Chemistry, 20, 1, 60-70 Bioconjugate chemistry, 20, 1, 60-70 Bioconjugate Chemistry, 20, 1, 60-70 2009/01 Refereed English Disclose to all
Y. Kobayashi; M. Nishikawa; K. Hyoudou; F. Yamashita; M. Hashida Kobayashi Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Y. Kobayashi; M. Nishikawa; K. Hyoudou; F. Yamashita; M. Hashida Hydrogen peroxide-mediated nuclear factor κB activation in both liver and tumor cells during initial stages of hepatic metastasis Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis. Hydrogen peroxide-mediated nuclear factor κB activation in both liver and tumor cells during initial stages of hepatic metastasis Cancer Science, 99, 8, 1546-1552 Cancer science, 99, 8, 1546-1552 Cancer Science, 99, 8, 1546-1552 2008/08 Refereed English Disclose to all
T. Okuda; S. Kawakami; M. Yokoyama; T. Yamamoto; F. Yamashita; M. Hashida Okuda T, Kawakami S, Yokoyama M, Yamamoto T, Yamashita F, Hashida M T. Okuda; S. Kawakami; M. Yokoyama; T. Yamamoto; F. Yamashita; M. Hashida Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice International Journal of Pharmaceutics, 357, 1-2, 318-322 International journal of pharmaceutics, 357, 1-2, 318-322 International Journal of Pharmaceutics, 357, 1-2, 318-322 2008/06 Refereed English Disclose to all
Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Use of mannosylated cationic liposomes/immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice. Use of mannosylated cationic liposomes/immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice Journal of Gene Medicine, 10, 4, 392-399 The journal of gene medicine, 10, 4, 392-399 Journal of Gene Medicine, 10, 4, 392-399 2008/04 Refereed English Disclose to all
Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Kuramoto Y, Kawakami S, Zhou S, Fukuda K, Yamashita F, Hashida M Y. Kuramoto; S. Kawakami; S. Zhou; K. Fukuda; F. Yamashita; M. Hashida Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice. Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice Journal of Controlled Release, 126, 3, 274-280 Journal of controlled release : official journal of the Controlled Release Society, 126, 3, 274-280 Journal of Controlled Release, 126, 3, 274-280 2008/03 Refereed English Disclose to all
F. Yamashita; H. Hara; T. Ito; M. Hashida Yamashita F, Hara H, Ito T, Hashida M F. Yamashita; H. Hara; T. Ito; M. Hashida Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism. Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism Journal of Chemical Information and Modeling, 48, 2, 364-369 Journal of chemical information and modeling, 48, 2, 364-369 Journal of Chemical Information and Modeling, 48, 2, 364-369 2008/02 Refereed English Disclose to all
H. Katsumi; M. Nishikawa; F. Yamashita; M. Hashida Katsumi H, Nishikawa M, Yamashita F, Hashida M H. Katsumi; M. Nishikawa; F. Yamashita; M. Hashida Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice. Prevention of hepatic ischemia/reperfusion injury by prolonged delivery of nitric oxide to the circulating blood in mice Transplantation, 85, 2, 264-269 Transplantation, 85, 2, 264-269 Transplantation, 85, 2, 264-269 2008/01 Refereed English Disclose to all
W. Wijagkanalan; S. Kawakami; M. Takenaga; R. Igarashi; F. Yamashita; M. Hashida Wijagkanalan W, Kawakami S, Takenaga M, Igarashi R, Yamashita F, Hashida M W. Wijagkanalan; S. Kawakami; M. Takenaga; R. Igarashi; F. Yamashita; M. Hashida Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats Journal of Controlled Release, 125, 2, 121-130 Journal of controlled release : official journal of the Controlled Release Society, 125, 2, 121-130 Journal of Controlled Release, 125, 2, 121-130 2008/01 Refereed English Disclose to all
O. Thanaketpaisarn; M. Nishikawa; T. Okabe; F. Yamashita; M. Hashida Thanaketpaisarn O, Nishikawa M, Okabe T, Yamashita F, Hashida M O. Thanaketpaisarn; M. Nishikawa; T. Okabe; F. Yamashita; M. Hashida Insertion of nuclear factor-κB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells Insertion of nuclear factor-kappaB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells. Insertion of nuclear factor-κB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells Journal of Biotechnology, 133, 1, 36-41 Journal of biotechnology, 133, 1, 36-41 Journal of Biotechnology, 133, 1, 36-41 2008/01 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Kobayashi; M. Ikemura; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Kobayashi Y, Ikemura M, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Kobayashi; M. Ikemura; F. Yamashita; M. Hashida SOD derivatives prevent metastatic tumor growth aggravated by tumor removal SOD derivatives prevent metastatic tumor growth aggravated by tumor removal. SOD derivatives prevent metastatic tumor growth aggravated by tumor removal Clinical and Experimental Metastasis, 25, 5, 531-536 Clinical & experimental metastasis, 25, 5, 531-536 Clinical and Experimental Metastasis, 25, 5, 531-536 2008 Refereed English Disclose to all
Y. Shiose; Y. Ochi; H. Kuga; F. Yamashita; M. Hashida Shiose Y, Ochi Y, Kuga H, Yamashita F, Hashida M Y. Shiose; Y. Ochi; H. Kuga; F. Yamashita; M. Hashida Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors. Relationship between drug release of DE-310, macromolecular prodrug of DX-8951f, and cathepsins activity in several tumors Biological and Pharmaceutical Bulletin, 30, 12, 2365-2370 Biological & pharmaceutical bulletin, 30, 12, 2365-2370 Biological and Pharmaceutical Bulletin, 30, 12, 2365-2370 2007/12 Refereed English Disclose to all
C. Feng; F. Yamashita; M. Hashida Feng C, Yamashita F, Hashida M C. Feng; F. Yamashita; M. Hashida Automated extraction of information from the literature on chemical-CYP3A4 interactions Automated extraction of information from the literature on chemical-CYP3A4 interactions. Automated extraction of information from the literature on chemical-CYP3A4 interactions Journal of Chemical Information and Modeling, 47, 6, 2449-2455 Journal of chemical information and modeling, 47, 6, 2449-2455 Journal of Chemical Information and Modeling, 47, 6, 2449-2455 2007/11 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; M. Ikemura; Y. Kobayashi; A. Mendelsohn; N. Miyazaki; Y. Tabata; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Ikemura M, Kobayashi Y, Mendelsohn A, Miyazaki N, Tabata Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; M. Ikemura; Y. Kobayashi; A. Mendelsohn; N. Miyazaki; Y. Tabata; F. Yamashita; M. Hashida Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells. Cationized catalase-loaded hydrogel for growth inhibition of peritoneally disseminated tumor cells Journal of Controlled Release, 122, 2, 151-158 Journal of controlled release : official journal of the Controlled Release Society, 122, 2, 151-158 Journal of Controlled Release, 122, 2, 151-158 2007/09 Refereed English Disclose to all
T. Nemoto; S. Kawakami; F. Yamashita; M. Hashida Nemoto T, Kawakami S, Yamashita F, Hashida M T. Nemoto; S. Kawakami; F. Yamashita; M. Hashida Efficient protection by cationized catalase against H<sub>2</sub>O<sub>2</sub> injury in primary cultured alveolar epithelial cells Efficient protection by cationized catalase against H2O2 injury in primary cultured alveolar epithelial cells. Efficient protection by cationized catalase against H<sub>2</sub>O<sub>2</sub> injury in primary cultured alveolar epithelial cells Journal of Controlled Release, 121, 1-2, 74-80 Journal of controlled release : official journal of the Controlled Release Society, 121, 1-2, 74-80 Journal of Controlled Release, 121, 1-2, 74-80 2007/08 Refereed English Disclose to all
Y. Lu; S. Kawakami; F. Yamashita; M. Hashida Lu Y, Kawakami S, Yamashita F, Hashida M Y. Lu; S. Kawakami; F. Yamashita; M. Hashida Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes. Development of an antigen-presenting cell-targeted DNA vaccine against melanoma by mannosylated liposomes Biomaterials, 28, 21, 3255-3262 Biomaterials, 28, 21, 3255-3262 Biomaterials, 28, 21, 3255-3262 2007/07 Refereed English Disclose to all
T. Terada; M. Mizobata; S. Kawakami; F. Yamashita; M. Hashida Terada T, Mizobata M, Kawakami S, Yamashita F, Hashida M T. Terada; M. Mizobata; S. Kawakami; F. Yamashita; M. Hashida Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes. Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes Journal of Controlled Release, 119, 3, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 119, 3, 262-270 Journal of Controlled Release, 119, 3, 262-270 2007/06 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Kobayashi; S. Mukai; M. Ikemura; Y. Kuramoto; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Kobayashi Y, Mukai S, Ikemura M, Kuramoto Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Kobayashi; S. Mukai; M. Ikemura; Y. Kuramoto; F. Yamashita; M. Hashida Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice. Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice Journal of Controlled Release, 119, 1, 121-127 Journal of controlled release : official journal of the Controlled Release Society, 119, 1, 121-127 Journal of Controlled Release, 119, 1, 121-127 2007/05 Refereed English Disclose to all
K. Shigeta; S. Kawakami; Y. Higuchi; T. Okuda; H. Yagi; F. Yamashita; M. Hashida Shigeta K, Kawakami S, Higuchi Y, Okuda T, Yagi H, Yamashita F, Hashida M K. Shigeta; S. Kawakami; Y. Higuchi; T. Okuda; H. Yagi; F. Yamashita; M. Hashida Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells. Novel histidine-conjugated galactosylated cationic liposomes for efficient hepatocyte-selective gene transfer in human hepatoma HepG2 cells Journal of Controlled Release, 118, 2, 262-270 Journal of controlled release : official journal of the Controlled Release Society, 118, 2, 262-270 Journal of Controlled Release, 118, 2, 262-270 2007/04 Refereed English Disclose to all
Y. Shiose; H. Kuga; F. Yamashita; M. Hashida Shiose Y, Kuga H, Yamashita F, Hashida M Y. Shiose; H. Kuga; F. Yamashita; M. Hashida Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f. Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f Journal of Pharmaceutical and Biomedical Analysis, 43, 4, 1290-1296 Journal of pharmaceutical and biomedical analysis, 43, 4, 1290-1296 Journal of Pharmaceutical and Biomedical Analysis, 43, 4, 1290-1296 2007/03 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Kuramoto; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Kuramoto; F. Yamashita; M. Hashida Analysis of in vivo nuclear factor-κB activation during liver inflammation in mice: Prevention by catalase delivery Analysis of in vivo nuclear factor-kappaB activation during liver inflammation in mice: prevention by catalase delivery. Analysis of in vivo nuclear factor-κB activation during liver inflammation in mice: Prevention by catalase delivery Molecular Pharmacology, 71, 2, 446-453 Molecular pharmacology, 71, 2, 446-453 Molecular Pharmacology, 71, 2, 446-453 2007/02 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida Higuchi Y, Kawakami S, Yamashita F, Hashida M Y. Higuchi; S. Kawakami; F. Yamashita; M. Hashida The potential role of fucosylated cationic liposome/NFκB decoy complexes in the treatment of cytokine-related liver disease The potential role of fucosylated cationic liposome/NFkappaB decoy complexes in the treatment of cytokine-related liver disease. The potential role of fucosylated cationic liposome/NFκB decoy complexes in the treatment of cytokine-related liver disease Biomaterials, 28, 3, 532-539 Biomaterials, 28, 3, 532-539 Biomaterials, 28, 3, 532-539 2007/01 Refereed English Disclose to all
T. Okuda; S. Kawakami; N. Akimoto; T. Niidome; F. Yamashita; M. Hashida Okuda T, Kawakami S, Akimoto N, Niidome T, Yamashita F, Hashida M T. Okuda; S. Kawakami; N. Akimoto; T. Niidome; F. Yamashita; M. Hashida PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice. PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice Journal of Controlled Release, 116, 3, 330-336 Journal of controlled release : official journal of the Controlled Release Society, 116, 3, 330-336 Journal of Controlled Release, 116, 3, 330-336 2006/12 Refereed English Disclose to all
S. Suzuki; S. Kawakami; N. Chansri; F. Yamashita; M. Hashida Suzuki S, Kawakami S, Chansri N, Yamashita F, Hashida M S. Suzuki; S. Kawakami; N. Chansri; F. Yamashita; M. Hashida Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes. Inhibition of pulmonary metastasis in mice by all-trans retinoic acid incorporated in cationic liposomes Journal of Controlled Release, 116, 1, 58-63 Journal of controlled release : official journal of the Controlled Release Society, 116, 1, 58-63 Journal of Controlled Release, 116, 1, 58-63 2006/11 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Umeyama; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Kobayashi Y, Umeyama Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Umeyama; F. Yamashita; M. Hashida PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal. PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal Free Radical Biology and Medicine, 41, 9, 1449-1458 Free radical biology & medicine, 41, 9, 1449-1458 Free Radical Biology and Medicine, 41, 9, 1449-1458 2006/11 Refereed English Disclose to all
Y. Kuramoto; M. Nishikawa; K. Hyoudou; F. Yamashita; M. Hashida Kuramoto Y, Nishikawa M, Hyoudou K, Yamashita F, Hashida M Y. Kuramoto; M. Nishikawa; K. Hyoudou; F. Yamashita; M. Hashida Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex. Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex Journal of Controlled Release, 115, 2, 226-233 Journal of controlled release : official journal of the Controlled Release Society, 115, 2, 226-233 Journal of Controlled Release, 115, 2, 226-233 2006/10 Refereed English Disclose to all
T. Terada; M. Mizobata; S. Kawakami; Y. Yabe; F. Yamashita; M. Hashida Terada T, Mizobata M, Kawakami S, Yabe Y, Yamashita F, Hashida M T. Terada; M. Mizobata; S. Kawakami; Y. Yabe; F. Yamashita; M. Hashida Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells. Basic fibroblast growth factor-binding peptide as a novel targeting ligand of drug carrier to tumor cells Journal of Drug Targeting, 14, 8, 536-545 Journal of drug targeting, 14, 8, 536-545 Journal of Drug Targeting, 14, 8, 536-545 2006/09 Refereed English Disclose to all
Y. Saito; S. Kawakami; Y. Yabe; F. Yamashita; M. Hashida Saito Y, Kawakami S, Yabe Y, Yamashita F, Hashida M Y. Saito; S. Kawakami; Y. Yabe; F. Yamashita; M. Hashida Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HepG2 cells Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HEPG2 cells. Intracellular trafficking is the important process that determines the optimal charge ratio on transfection by galactosylated lipoplex in HepG2 cells Biological and Pharmaceutical Bulletin, 29, 9, 1986-1990 Biological & pharmaceutical bulletin, 29, 9, 1986-1990 Biological and Pharmaceutical Bulletin, 29, 9, 1986-1990 2006/09 Refereed English Disclose to all
S.-F. Ma; M. Nishikawa; Y. Yabe; F. Yamashita; M. Hashida Ma SF, Nishikawa M, Yabe Y, Yamashita F, Hashida M S.-F. Ma; M. Nishikawa; Y. Yabe; F. Yamashita; M. Hashida Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution. Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution Biological and Pharmaceutical Bulletin, 29, 9, 1926-1930 Biological & pharmaceutical bulletin, 29, 9, 1926-1930 Biological and Pharmaceutical Bulletin, 29, 9, 1926-1930 2006/09 Refereed English Disclose to all
N. Chansri; S. Kawakami; F. Yamashita; M. Hashida Chansri N, Kawakami S, Yamashita F, Hashida M N. Chansri; S. Kawakami; F. Yamashita; M. Hashida Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice. Inhibition of liver metastasis by all-trans retinoic acid incorporated into O/W emulsions in mice International Journal of Pharmaceutics, 321, 1-2, 42-49 International journal of pharmaceutics, 321, 1-2, 42-49 International Journal of Pharmaceutics, 321, 1-2, 42-49 2006/09 Refereed English Disclose to all
K. Inoue; K. Harada; K. Takenaka; S. Uehara; M. Kono; T. Shimizu; T. Takasuga; K. Senthilkumar; F. Yamashita; A. Koizumi Inoue K, Harada K, Takenaka K, Uehara S, Kono M, Shimizu T, Takasuga T, Senthilkumar K, Yamashita F, Koizumi A K. Inoue; K. Harada; K. Takenaka; S. Uehara; M. Kono; T. Shimizu; T. Takasuga; K. Senthilkumar; F. Yamashita; A. Koizumi Levels and concentration ratios of polychlorinated biphenyls and polybrominated diphenyl ethers in serum and breast milk in Japanese mothers Levels and concentration ratios of polychlorinated biphenyls and polybrominated diphenyl ethers in serum and breast milk in Japanese mothers. Levels and concentration ratios of polychlorinated biphenyls and polybrominated diphenyl ethers in serum and breast milk in Japanese mothers Environmental Health Perspectives, 114, 8, 1179-1185 Environmental health perspectives, 114, 8, 1179-1185 Environmental Health Perspectives, 114, 8, 1179-1185 2006/08 Refereed English Disclose to all
W. Yeeprae; S. Kawakami; F. Yamashita; M. Hashida Yeeprae W, Kawakami S, Yamashita F, Hashida M W. Yeeprae; S. Kawakami; F. Yamashita; M. Hashida Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages. Effect of mannose density on mannose receptor-mediated cellular uptake of mannosylated O/W emulsions by macrophages Journal of Controlled Release, 114, 2, 193-201 Journal of controlled release : official journal of the Controlled Release Society, 114, 2, 193-201 Journal of Controlled Release, 114, 2, 193-201 2006/08 Refereed English Disclose to all
T. Okuda; S. Kawakami; T. Maeie; T. Niidome; F. Yamashita; M. Hashida Okuda T, Kawakami S, Maeie T, Niidome T, Yamashita F, Hashida M T. Okuda; S. Kawakami; T. Maeie; T. Niidome; F. Yamashita; M. Hashida Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration. Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration Journal of Controlled Release, 114, 1, 69-77 Journal of controlled release : official journal of the Controlled Release Society, 114, 1, 69-77 Journal of Controlled Release, 114, 1, 69-77 2006/08 Refereed English Disclose to all
Y. Hattori; S. Kawakami; K. Nakamura; F. Yamashita; M. Hashida Hattori Y, Kawakami S, Nakamura K, Yamashita F, Hashida M Y. Hattori; S. Kawakami; K. Nakamura; F. Yamashita; M. Hashida Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route. Efficient gene transfer into macrophages and dendritic cells by in vivo gene delivery with mannosylated lipoplex via the intraperitoneal route Journal of Pharmacology and Experimental Therapeutics, 318, 2, 828-834 The Journal of pharmacology and experimental therapeutics, 318, 2, 828-834 Journal of Pharmacology and Experimental Therapeutics, 318, 2, 828-834 2006/08 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; S. Fumoto; F. Yamashita; M. Hashida Higuchi Y, Kawakami S, Fumoto S, Yamashita F, Hashida M Y. Higuchi; S. Kawakami; S. Fumoto; F. Yamashita; M. Hashida Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration. Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration Biological and Pharmaceutical Bulletin, 29, 7, 1521-1523 Biological & pharmaceutical bulletin, 29, 7, 1521-1523 Biological and Pharmaceutical Bulletin, 29, 7, 1521-1523 2006/07 Refereed English Disclose to all
Y. Hattori; S. Kawakami; Y. Lu; K. Nakamura; F. Yamashita; M. Hashida Hattori Y, Kawakami S, Lu Y, Nakamura K, Yamashita F, Hashida M Y. Hattori; S. Kawakami; Y. Lu; K. Nakamura; F. Yamashita; M. Hashida Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration. Enhanced DNA vaccine potency by mannosylated lipoplex after intraperitoneal administration Journal of Gene Medicine, 8, 7, 824-834 The journal of gene medicine, 8, 7, 824-834 Journal of Gene Medicine, 8, 7, 824-834 2006/07 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; M. Oka; Y. Yabe; F. Yamashita; M. Hashida Higuchi Y, Kawakami S, Oka M, Yabe Y, Yamashita F, Hashida M Y. Higuchi; S. Kawakami; M. Oka; Y. Yabe; F. Yamashita; M. Hashida Intravenous administration of mannosylated cationic liposome/NFκB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model Intravenous administration of mannosylated cationic liposome/NFkappaB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model. Intravenous administration of mannosylated cationic liposome/NFκB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model FEBS Letters, 580, 15, 3706-3714 FEBS letters, 580, 15, 3706-3714 FEBS Letters, 580, 15, 3706-3714 2006/06 Refereed English Disclose to all
T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Terada T, Nishikawa M, Yamashita F, Hashida M T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins. Analysis of the molecular interaction between mannosylated proteins and serum mannan-binding lectins International Journal of Pharmaceutics, 316, 1-2, 117-123 International journal of pharmaceutics, 316, 1-2, 117-123 International Journal of Pharmaceutics, 316, 1-2, 117-123 2006/06 Refereed English Disclose to all
T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Terada T, Nishikawa M, Yamashita F, Hashida M T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy. Analysis of the molecular interaction of glycosylated proteins with rabbit liver asialoglycoprotein receptors using surface plasmon resonance spectroscopy Journal of Pharmaceutical and Biomedical Analysis, 41, 3, 966-972 Journal of pharmaceutical and biomedical analysis, 41, 3, 966-972 Journal of Pharmaceutical and Biomedical Analysis, 41, 3, 966-972 2006/06 Refereed English Disclose to all
S. Kawakami; Y. Ito; P. Charoensit; F. Yamashita; M. Hashida Kawakami S, Ito Y, Charoensit P, Yamashita F, Hashida M S. Kawakami; Y. Ito; P. Charoensit; F. Yamashita; M. Hashida Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice Journal of Pharmacology and Experimental Therapeutics, 317, 3, 1382-1390 The Journal of pharmacology and experimental therapeutics, 317, 3, 1382-1390 Journal of Pharmacology and Experimental Therapeutics, 317, 3, 1382-1390 2006/06 Refereed English Disclose to all
F. Yamashita; T. Itoh; H. Hara; M. Hashida Yamashita F, Itoh T, Hara H, Hashida M F. Yamashita; T. Itoh; H. Hara; M. Hashida Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique. Visualization of large-scale aqueous solubility data using a novel hierarchical data visualization technique Journal of Chemical Information and Modeling, 46, 3, 1054-1059 Journal of chemical information and modeling, 46, 3, 1054-1059 Journal of Chemical Information and Modeling, 46, 3, 1054-1059 2006/05 Refereed English Disclose to all
T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Terada T, Nishikawa M, Yamashita F, Hashida M T. Terada; M. Nishikawa; F. Yamashita; M. Hashida Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes. Influence of cholesterol composition on the association of serum mannan-binding proteins with mannosylated liposomes Biological and Pharmaceutical Bulletin, 29, 4, 613-618 Biological & pharmaceutical bulletin, 29, 4, 613-618 Biological and Pharmaceutical Bulletin, 29, 4, 613-618 2006/04 Refereed English Disclose to all
T. Terada; M. Iwai; S. Kawakami; F. Yamashita; M. Hashida Terada T, Iwai M, Kawakami S, Yamashita F, Hashida M T. Terada; M. Iwai; S. Kawakami; F. Yamashita; M. Hashida Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting. Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting Journal of Controlled Release, 111, 3, 333-342 Journal of controlled release : official journal of the Controlled Release Society, 111, 3, 333-342 Journal of Controlled Release, 111, 3, 333-342 2006/04 Refereed English Disclose to all
N. Ishimoto; T. Nemoto; K. Nagayoshi; F. Yamashita; M. Hashida Ishimoto N, Nemoto T, Nagayoshi K, Yamashita F, Hashida M N. Ishimoto; T. Nemoto; K. Nagayoshi; F. Yamashita; M. Hashida Improved anti-oxidant activity of superoxide dismutase by direct chemical modification Improved anti-oxidant activity of superoxide dismutase by direct chemical modification. Improved anti-oxidant activity of superoxide dismutase by direct chemical modification Journal of Controlled Release, 111, 1-2, 204-211 Journal of controlled release : official journal of the Controlled Release Society, 111, 1-2, 204-211 Journal of Controlled Release, 111, 1-2, 204-211 2006/03 Refereed English Disclose to all
S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida Kawakami S, Suzuki S, Yamashita F, Hashida M S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes. Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes Journal of Controlled Release, 110, 3, 514-521 Journal of controlled release : official journal of the Controlled Release Society, 110, 3, 514-521 Journal of Controlled Release, 110, 3, 514-521 2006/02 Refereed English Disclose to all
S.-F. Ma; M. Nishikawa; H. Katsumi; F. Yamashita; M. Hashida Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M S.-F. Ma; M. Nishikawa; H. Katsumi; F. Yamashita; M. Hashida Liver targeting of catalase by cationization for prevention of acute liver failure in mice Liver targeting of catalase by cationization for prevention of acute liver failure in mice. Liver targeting of catalase by cationization for prevention of acute liver failure in mice Journal of Controlled Release, 110, 2, 273-282 Journal of controlled release : official journal of the Controlled Release Society, 110, 2, 273-282 Journal of Controlled Release, 110, 2, 273-282 2006/01 Refereed English Disclose to all
T. Kuramoto; M. Nishikawa; O. Thanaketpaisarn; T. Okabe; F. Yamashita; M. Hashida Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F, Hashida M T. Kuramoto; M. Nishikawa; O. Thanaketpaisarn; T. Okabe; F. Yamashita; M. Hashida Use of lipoplex-induced nuclear factor-κB activation to enhance transgene expression by lipoplex in mouse lung Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung. Use of lipoplex-induced nuclear factor-κB activation to enhance transgene expression by lipoplex in mouse lung Journal of Gene Medicine, 8, 1, 53-62 The journal of gene medicine, 8, 1, 53-62 Journal of Gene Medicine, 8, 1, 53-62 2006/01 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Kuramoto; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Kobayashi; Y. Kuramoto; F. Yamashita; M. Hashida Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase. Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase Clinical and Experimental Metastasis, 23, 5-6, 269-278 Clinical & experimental metastasis, 23, 5-6, 269-278 Clinical and Experimental Metastasis, 23, 5-6, 269-278 2006 Refereed English Disclose to all
F. Yamashita; S.-I. Fujiwara; S. Wanchana; M. Hashida Yamashita F, Fujiwara S, Wanchana S, Hashida M F. Yamashita; S.-I. Fujiwara; S. Wanchana; M. Hashida Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method. Quantitative structure/activity relationship modelling of pharmacokinetic properties using genetic algorithm-combined partial least squares method Journal of Drug Targeting, 14, 7, 496-504 Journal of drug targeting, 14, 7, 496-504 Journal of Drug Targeting, 14, 7, 496-504 2006 Refereed English Disclose to all
S. Kawakami; P. Opanasopit; M. Yokoyama; N. Chansri; T. Yamamoto; T. Okano; F. Yamashita; M. Hashida Kawakami S, Opanasopit P, Yokoyama M, Chansri N, Yamamoto T, Okano T, Yamashita F, Hashida M S. Kawakami; P. Opanasopit; M. Yokoyama; N. Chansri; T. Yamamoto; T. Okano; F. Yamashita; M. Hashida Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration. Biodistribution characteristics of all-trans retinoic acid incorporated in liposomes and polymeric micelles following intravenous administration Journal of Pharmaceutical Sciences, 94, 12, 2606-2615 Journal of pharmaceutical sciences, 94, 12, 2606-2615 Journal of Pharmaceutical Sciences, 94, 12, 2606-2615 2005/12 Refereed English Disclose to all
S. Kawakami; Y. Ito; S. Fumoto; F. Yamashita; M. Hashida Kawakami S, Ito Y, Fumoto S, Yamashita F, Hashida M S. Kawakami; Y. Ito; S. Fumoto; F. Yamashita; M. Hashida Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation. Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation Journal of Gene Medicine, 7, 12, 1526-1533 The journal of gene medicine, 7, 12, 1526-1533 Journal of Gene Medicine, 7, 12, 1526-1533 2005/12 Refereed English Disclose to all
Y. Hattori; S. Suzuki; S. Kawakami; F. Yamashita; M. Hashida Hattori Y, Suzuki S, Kawakami S, Yamashita F, Hashida M Y. Hattori; S. Suzuki; S. Kawakami; F. Yamashita; M. Hashida The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route. The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route Journal of Controlled Release, 108, 2-3, 484-495 Journal of controlled release : official journal of the Controlled Release Society, 108, 2-3, 484-495 Journal of Controlled Release, 108, 2-3, 484-495 2005/11 Refereed English Disclose to all
S. Fumoto; S. Kawakami; K. Shigeta; Y. Higuchi; F. Yamashita; M. Hashida Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, Hashida M S. Fumoto; S. Kawakami; K. Shigeta; Y. Higuchi; F. Yamashita; M. Hashida Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex Journal of Pharmacology and Experimental Therapeutics, 315, 2, 484-493 The Journal of pharmacology and experimental therapeutics, 315, 2, 484-493 Journal of Pharmacology and Experimental Therapeutics, 315, 2, 484-493 2005/11 Refereed English Disclose to all
S. Harada; F. Yamashita; M. Hashida Harada S, Yamashita F, Hashida M S. Harada; F. Yamashita; M. Hashida Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Estimation of in vivo percutaneous absorption of emedastine from bile excretion data using a deconvolution method. Drug metabolism and pharmacokinetics., 20, 5, 331-336 Drug metabolism and pharmacokinetics, 20, 5, 331-336 Drug metabolism and pharmacokinetics., 20, 5, 331-336 2005/10 Refereed English Disclose to all
C. Managit; S. Kawakami; F. Yamashita; M. Hashida Managit C, Kawakami S, Yamashita F, Hashida M C. Managit; S. Kawakami; F. Yamashita; M. Hashida Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes Journal of Pharmaceutical Sciences, 94, 10, 2266-2275 Journal of pharmaceutical sciences, 94, 10, 2266-2275 Journal of Pharmaceutical Sciences, 94, 10, 2266-2275 2005/10 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Higuchi Y, Kawakami S, Nishikawa M, Yamashita F, Hashida M Y. Higuchi; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Intracellular distribution of NFκB decoy and its inhibitory effect on TNFα production by LPS stimulated RAW 264.7 cells Intracellular distribution of NFkappaB decoy and its inhibitory effect on TNFalpha production by LPS stimulated RAW 264.7 cells. Intracellular distribution of NFκB decoy and its inhibitory effect on TNFα production by LPS stimulated RAW 264.7 cells Journal of Controlled Release, 107, 2, 373-382 Journal of controlled release : official journal of the Controlled Release Society, 107, 2, 373-382 Journal of Controlled Release, 107, 2, 373-382 2005/10 Refereed English Disclose to all
W. Yeeprae; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Yeeprae W, Kawakami S, Higuchi Y, Yamashita F, Hashida M W. Yeeprae; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice. Biodistribution characteristics of mannosylated and fucosylated O/W emulsions in mice Journal of Drug Targeting, 13, 8-9, 479-487 Journal of drug targeting, 13, 8-9, 479-487 Journal of Drug Targeting, 13, 8-9, 479-487 2005/09 Refereed English Disclose to all
Y. Arakawa; S. Kawakami; F. Yamashita; M. Hashida Arakawa Y, Kawakami S, Yamashita F, Hashida M Y. Arakawa; S. Kawakami; F. Yamashita; M. Hashida Effect of low-molecular-weight β-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms Effect of low-molecular-weight beta-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms. Effect of low-molecular-weight β-cyclodextrin polymer on release of drugs from mucoadhesive buccal film dosage forms Biological and Pharmaceutical Bulletin, 28, 9, 1679-1683 Biological & pharmaceutical bulletin, 28, 9, 1679-1683 Biological and Pharmaceutical Bulletin, 28, 9, 1679-1683 2005/09 Refereed English Disclose to all
C. Managit; S. Kawakami; F. Yamashita; M. Hashida Managit C, Kawakami S, Yamashita F, Hashida M C. Managit; S. Kawakami; F. Yamashita; M. Hashida Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells. Uptake characteristics of galactosylated emulsion by HepG2 hepatoma cells International Journal of Pharmaceutics, 301, 1-2, 255-261 International journal of pharmaceutics, 301, 1-2, 255-261 International Journal of Pharmaceutics, 301, 1-2, 255-261 2005/09 Refereed English Disclose to all
H. Katsumi; M. Nishikawa; F. Yamashita; M. Hashida Katsumi H, Nishikawa M, Yamashita F, Hashida M H. Katsumi; M. Nishikawa; F. Yamashita; M. Hashida Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-Nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo. Development of polyethylene glycol-conjugated poly-S-nitrosated serum albumin, a novel S-nitrosothiol for prolonged delivery of nitric oxide in the blood circulation in vivo Journal of Pharmacology and Experimental Therapeutics, 314, 3, 1117-1124 The Journal of pharmacology and experimental therapeutics, 314, 3, 1117-1124 Journal of Pharmacology and Experimental Therapeutics, 314, 3, 1117-1124 2005/09 Refereed English Disclose to all
M. Hashida; S. Kawakami; F. Yamashita Hashida M, Kawakami S, Yamashita F M. Hashida; S. Kawakami; F. Yamashita Lipid carrier systems for targeted drug and gene delivery Lipid carrier systems for targeted drug and gene delivery. Lipid carrier systems for targeted drug and gene delivery Chemical and Pharmaceutical Bulletin, 53, 8, 871-880 Chemical & pharmaceutical bulletin, 53, 8, 871-880 Chemical and Pharmaceutical Bulletin, 53, 8, 871-880 2005/08 Refereed English Disclose to all
O. Thanaketpaisarn; M. Nishikawa; F. Yamashita; M. Hashida Thanaketpaisarn O, Nishikawa M, Yamashita F, Hashida M O. Thanaketpaisarn; M. Nishikawa; F. Yamashita; M. Hashida Tissue-specific characteristics of in Vivo electric gene: Transfer by tissue and intravenous injection of plasmid DNA Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. Tissue-specific characteristics of in Vivo electric gene: Transfer by tissue and intravenous injection of plasmid DNA Pharmaceutical Research, 22, 6, 883-891 Pharmaceutical research, 22, 6, 883-891 Pharmaceutical Research, 22, 6, 883-891 2005/06 Refereed English Disclose to all
S.-F. Ma; M. Nishikawa; H. Katsumi; F. Yamashita; M. Hashida Ma SF, Nishikawa M, Katsumi H, Yamashita F, Hashida M S.-F. Ma; M. Nishikawa; H. Katsumi; F. Yamashita; M. Hashida Cationic charge-dependent hepatic delivery of amidated serum albumin Cationic charge-dependent hepatic delivery of amidated serum albumin. Cationic charge-dependent hepatic delivery of amidated serum albumin Journal of Controlled Release, 102, 3, 583-594 Journal of controlled release : official journal of the Controlled Release Society, 102, 3, 583-594 Journal of Controlled Release, 102, 3, 583-594 2005/02 Refereed English Disclose to all
S. Harada; Y. Nakada; F. Yamashita; M. Hashida Harada S, Nakada Y, Yamashita F, Hashida M S. Harada; Y. Nakada; F. Yamashita; M. Hashida Biopharmaceutical considerations on antihistamine effects of topically administered emedastine Biopharmaceutical considerations on antihistamine effects of topically administered emedastine. Biopharmaceutical considerations on antihistamine effects of topically administered emedastine Journal of Pharmaceutical Sciences, 94, 1, 17-24 Journal of pharmaceutical sciences, 94, 1, 17-24 Journal of Pharmaceutical Sciences, 94, 1, 17-24 2005/01 Refereed English Disclose to all
K. Nagayoshi; T. Nemoto; S. Yokoyama; F. Yamashita; M. Hashida Nagayoshi K, Nemoto T, Yokoyama S, Yamashita F, Hashida M K. Nagayoshi; T. Nemoto; S. Yokoyama; F. Yamashita; M. Hashida Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Drug metabolism and pharmacokinetics, 19, 6, 407-412 Drug metabolism and pharmacokinetics, 19, 6, 407-412 Drug metabolism and pharmacokinetics, 19, 6, 407-412 2004/12 Refereed English Disclose to all
Y. Higuchi; M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Higuchi Y, Nishikawa M, Kawakami S, Yamashita F, Hashida M Y. Higuchi; M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells. Uptake characteristics of mannosylated and fucosylated bovine serum albumin in primary cultured rat sinusoidal endothelial cells and Kupffer cells International Journal of Pharmaceutics, 287, 1-2, 147-154 International journal of pharmaceutics, 287, 1-2, 147-154 International Journal of Pharmaceutics, 287, 1-2, 147-154 2004/12 Refereed English Disclose to all
S. Wanchana; F. Yamashita; H. Hara; S.-I. Fujiwara; M. Akamatsu; M. Hashida Wanchana S, Yamashita F, Hara H, Fujiwara S, Akamatsu M, Hashida M S. Wanchana; F. Yamashita; H. Hara; S.-I. Fujiwara; M. Akamatsu; M. Hashida Two- and three-dimensional QSAR of carrier-mediated transport of β-lactam antibiotics in Caco-2 cells Two- and three-dimensional QSAR of carrier-mediated transport of beta-lactam antibiotics in Caco-2 cells. Two- and three-dimensional QSAR of carrier-mediated transport of β-lactam antibiotics in Caco-2 cells Journal of Pharmaceutical Sciences, 93, 12, 3057-3065 Journal of pharmaceutical sciences, 93, 12, 3057-3065 Journal of Pharmaceutical Sciences, 93, 12, 3057-3065 2004/12 Refereed English Disclose to all
K. Hyoudou; M. Nishikawa; Y. Umeyama; Y. Kobayashi; F. Yamashita; M. Hashida Hyoudou K, Nishikawa M, Umeyama Y, Kobayashi Y, Yamashita F, Hashida M K. Hyoudou; M. Nishikawa; Y. Umeyama; Y. Kobayashi; F. Yamashita; M. Hashida Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: Quantitative analysis with firefly luciferase-expressing melanoma cells Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells. Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: Quantitative analysis with firefly luciferase-expressing melanoma cells Clinical Cancer Research, 10, 22, 7685-7691 Clinical cancer research : an official journal of the American Association for Cancer Research, 10, 22, 7685-7691 Clinical Cancer Research, 10, 22, 7685-7691 2004/11 Refereed English Disclose to all
F. Yamashita; M. Hashida Yamashita F, Hashida M F. Yamashita; M. Hashida In silico approaches for predicting ADME properties of drugs. In silico approaches for predicting ADME properties of drugs. In silico approaches for predicting ADME properties of drugs. Drug metabolism and pharmacokinetics, 19, 5, 327-338 Drug metabolism and pharmacokinetics, 19, 5, 327-338 Drug metabolism and pharmacokinetics, 19, 5, 327-338 2004/10 Refereed English Disclose to all
S. Fumoto; S. Kawakami; Y. Ito; K. Shigeta; F. Yamashita; M. Hashida Fumoto S, Kawakami S, Ito Y, Shigeta K, Yamashita F, Hashida M S. Fumoto; S. Kawakami; Y. Ito; K. Shigeta; F. Yamashita; M. Hashida Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation. Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation Molecular Therapy, 10, 4, 719-729 Molecular therapy : the journal of the American Society of Gene Therapy, 10, 4, 719-729 Molecular Therapy, 10, 4, 719-729 2004/10 Refereed English Disclose to all
M. Nakamura; S. Yamaguchi; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida Nakamura M, Yamaguchi S, Watanabe Y, Yamashita F, Takakura Y, Hashida M M. Nakamura; S. Yamaguchi; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida Exogenous expression of interferon-β in cultured brain microvessel endothelial cells Exogenous expression of interferon-beta in cultured brain microvessel endothelial cells. Exogenous expression of interferon-β in cultured brain microvessel endothelial cells Biological and Pharmaceutical Bulletin, 27, 9, 1441-1443 Biological & pharmaceutical bulletin, 27, 9, 1441-1443 Biological and Pharmaceutical Bulletin, 27, 9, 1441-1443 2004/09 Refereed English Disclose to all
H. Katsumi; M. Nishikawa; S.-F. Ma; F. Yamashita; M. Hashida Katsumi H, Nishikawa M, Ma SF, Yamashita F, Hashida M H. Katsumi; M. Nishikawa; S.-F. Ma; F. Yamashita; M. Hashida Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: Delivery of nitric oxide in vivo Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: delivery of nitric oxide in vivo. Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: Delivery of nitric oxide in vivo Journal of Pharmaceutical Sciences, 93, 9, 2343-2352 Journal of pharmaceutical sciences, 93, 9, 2343-2352 Journal of Pharmaceutical Sciences, 93, 9, 2343-2352 2004/09 Refereed English Disclose to all
M. Yamada; M. Nishikawa; S. Kawakami; Y. Hattori; T. Nakano; F. Yamashita; M. Hashida Yamada M, Nishikawa M, Kawakami S, Hattori Y, Nakano T, Yamashita F, Hashida M M. Yamada; M. Nishikawa; S. Kawakami; Y. Hattori; T. Nakano; F. Yamashita; M. Hashida Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice. Tissue and intrahepatic distribution and subcellular localization of a mannosylated lipoplex after intravenous administration in mice Journal of Controlled Release, 98, 1, 157-167 Journal of controlled release : official journal of the Controlled Release Society, 98, 1, 157-167 Journal of Controlled Release, 98, 1, 157-167 2004/07 Refereed English Disclose to all
E. Ishida; C. Managit; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Ishida E, Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M E. Ishida; C. Managit; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice. Biodistribution characteristics of galactosylated emulsions and incorporated probucol for hepatocyte-selective targeting of lipophilic drugs in mice Pharmaceutical Research, 21, 6, 932-939 Pharmaceutical research, 21, 6, 932-939 Pharmaceutical Research, 21, 6, 932-939 2004/06 Refereed English Disclose to all
Y. Hattori; S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida Hattori Y, Kawakami S, Suzuki S, Yamashita F, Hashida M Y. Hattori; S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice. Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice Biochemical and Biophysical Research Communications, 317, 4, 992-999 Biochemical and biophysical research communications, 317, 4, 992-999 Biochemical and Biophysical Research Communications, 317, 4, 992-999 2004/05 Refereed English Disclose to all
M. Nakamura; M. Maruyama; F. Yamashita; Y. Takakura; M. Hashida; Y. Watanabe Nakamura M, Maruyama M, Yamashita F, Takakura Y, Hashida M, Watanabe Y M. Nakamura; M. Maruyama; F. Yamashita; Y. Takakura; M. Hashida; Y. Watanabe Expression and visualization of a human interferon-β-enhanced green fluorescent protein chimeric molecule in cultured cells Expression and visualization of a human interferon-beta-enhanced green fluorescent protein chimeric molecule in cultured cells. Expression and visualization of a human interferon-β-enhanced green fluorescent protein chimeric molecule in cultured cells Biological and Pharmaceutical Bulletin, 27, 3, 411-414 Biological & pharmaceutical bulletin, 27, 3, 411-414 Biological and Pharmaceutical Bulletin, 27, 3, 411-414 2004/03 Refereed English Disclose to all
M. Nishikawa; A. Tamada; K. Hyoudou; Y. Umeyama; Y. Takahashi; Y. Kobayashi; H. Kumai; E. Ishida; F. Staud; Y. Yabe; Y. Takakura; F. Yamashita; M. Hashida Nishikawa M, Tamada A, Hyoudou K, Umeyama Y, Takahashi Y, Kobayashi Y, Kumai H, Ishida E, Staud F, Yabe Y, Takakura Y, Yamashita F, Hashida M M. Nishikawa; A. Tamada; K. Hyoudou; Y. Umeyama; Y. Takahashi; Y. Kobayashi; H. Kumai; E. Ishida; F. Staud; Y. Yabe; Y. Takakura; F. Yamashita; M. Hashida Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice Clinical and Experimental Metastasis, 21, 3, 213-221 Clinical & experimental metastasis, 21, 3, 213-221 Clinical and Experimental Metastasis, 21, 3, 213-221 2004 Refereed English Disclose to all
C. Managit; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Managit C, Kawakami S, Nishikawa M, Yamashita F, Hashida M C. Managit; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Targeted and sustained drug delivery using PEGylated galactosylated liposomes Targeted and sustained drug delivery using PEGylated galactosylated liposomes. Targeted and sustained drug delivery using PEGylated galactosylated liposomes International Journal of Pharmaceutics, 266, 1-2, 77-84 International journal of pharmaceutics, 266, 1-2, 77-84 International Journal of Pharmaceutics, 266, 1-2, 77-84 2003/11 Refereed English Disclose to all
S.-I. Fujiwara; F. Yamashita; M. Hashida Fujiwara S, Yamashita F, Hashida M S.-I. Fujiwara; F. Yamashita; M. Hashida QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept. QSAR analysis of interstudy variable skin permeability based on the "latent membrane permeability" concept Journal of Pharmaceutical Sciences, 92, 10, 1939-1946 Journal of pharmaceutical sciences, 92, 10, 1939-1946 Journal of Pharmaceutical Sciences, 92, 10, 1939-1946 2003/10 Refereed English Disclose to all
S. Fumoto; F. Nakadori; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Fumoto S, Nakadori F, Kawakami S, Nishikawa M, Yamashita F, Hashida M S. Fumoto; F. Nakadori; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Analysis of hepatic disposition of galactosylated cationic liposome/ plasmid DNA complexes in perfused rat liver Analysis of hepatic disposition of galactosylated cationic liposome/plasmid DNA complexes in perfused rat liver. Analysis of hepatic disposition of galactosylated cationic liposome/ plasmid DNA complexes in perfused rat liver Pharmaceutical Research, 20, 9, 1452-1459 Pharmaceutical research, 20, 9, 1452-1459 Pharmaceutical Research, 20, 9, 1452-1459 2003/09 Refereed English Disclose to all
S. Wanchana; F. Yamashita; M. Hashida Wanchana S, Yamashita F, Hashida M S. Wanchana; F. Yamashita; M. Hashida QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method. QSAR analysis of the inhibition of recombinant CYP 3A4 activity by structurally diverse compounds using a genetic algorithm-combined partial least squares method Pharmaceutical Research, 20, 9, 1401-1408 Pharmaceutical research, 20, 9, 1401-1408 Pharmaceutical Research, 20, 9, 1401-1408 2003/09 Refereed English Disclose to all
M. Nishikawa; T. Nakano; T. Okabe; N. Hamaguchi; Y. Yamasaki; Y. Takakura; F. Yamashita; M. Hashida Nishikawa M, Nakano T, Okabe T, Hamaguchi N, Yamasaki Y, Takakura Y, Yamashita F, Hashida M M. Nishikawa; T. Nakano; T. Okabe; N. Hamaguchi; Y. Yamasaki; Y. Takakura; F. Yamashita; M. Hashida Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study. Residualizing indium-111-radiolabel for plasmid DNA and its application to tissue distribution study Bioconjugate Chemistry, 14, 5, 955-961 Bioconjugate chemistry, 14, 5, 955-961 Bioconjugate Chemistry, 14, 5, 955-961 2003/09 Refereed English Disclose to all
F. Yamashita; M. Hashida Yamashita F, Hashida M F. Yamashita; M. Hashida Mechanistic and empirical modeling of skin permeation of drugs Mechanistic and empirical modeling of skin permeation of drugs. Mechanistic and empirical modeling of skin permeation of drugs Advanced Drug Delivery Reviews, 55, 9, 1185-1199 Advanced drug delivery reviews, 55, 9, 1185-1199 Advanced Drug Delivery Reviews, 55, 9, 1185-1199 2003/09 Refereed English Disclose to all
F. Sakurai; T. Terada; M. Maruyama; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida Sakurai F, Terada T, Maruyama M, Watanabe Y, Yamashita F, Takakura Y, Hashida M F. Sakurai; T. Terada; M. Maruyama; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-β gene and poly I: Poly C in a murine lung metastasis model Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model. Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-β gene and poly I: Poly C in a murine lung metastasis model Cancer Gene Therapy, 10, 9, 661-668 Cancer gene therapy, 10, 9, 661-668 Cancer Gene Therapy, 10, 9, 661-668 2003/09 Refereed English Disclose to all
X. Wu; F. Yamashita; M. Hashida; X. Chen; Z. Hu Wu X, Yamashita F, Hashida M, Chen X, Hu Z X. Wu; F. Yamashita; M. Hashida; X. Chen; Z. Hu Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies Talanta, 59, 5, 965-971 Talanta, 59, 5, 965-971 Talanta, 59, 5, 965-971 2003/04 Refereed English Disclose to all
K. Morimoto; M. Nishikawa; S. Kawakami; T. Nakano; Y. Hattori; S. Fumoto; F. Yamashita; M. Hashida Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, Hashida M K. Morimoto; M. Nishikawa; S. Kawakami; T. Nakano; Y. Hattori; S. Fumoto; F. Yamashita; M. Hashida Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver Molecular Therapy, 7, 2, 254-261 Molecular therapy : the journal of the American Society of Gene Therapy, 7, 2, 254-261 Molecular Therapy, 7, 2, 254-261 2003/02 Refereed English Disclose to all
Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Fumoto S, Kawakami S, Ishizuka M, Nishikawa M, Yamashita F, Hashida M Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver. Drug metabolism and pharmacokinetics, 18, 4, 230-237 Drug metabolism and pharmacokinetics, 18, 4, 230-237 Drug metabolism and pharmacokinetics, 18, 4, 230-237 2003 Refereed Disclose to all
M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Nishikawa M, Kawakami S, Yamashita F, Hashida M M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer. Glycosylated cationic liposomes for carbohydrate receptor-mediated gene transfer Methods in Enzymology, 373, 384-399 Methods in enzymology, 373, 384-399 Methods in Enzymology, 373, 384-399 2003 Refereed English Disclose to all
Y. Yabe; N. Kobayashi; M. Nishikawa; K. Mihara; F. Yamashita; Y. Takakura; M. Hashida Yabe Y, Kobayashi N, Nishikawa M, Mihara K, Yamashita F, Takakura Y, Hashida M Y. Yabe; N. Kobayashi; M. Nishikawa; K. Mihara; F. Yamashita; Y. Takakura; M. Hashida Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver. Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver Pharmaceutical Research, 19, 12, 1815-1821 Pharmaceutical research, 19, 12, 1815-1821 Pharmaceutical Research, 19, 12, 1815-1821 2002/12 Refereed English Disclose to all
A. Murao; M. Nishikawa; C. Managit; J. Wong; S. Kawakami; F. Yamashita; M. Hashida Murao A, Nishikawa M, Managit C, Wong J, Kawakami S, Yamashita F, Hashida M A. Murao; M. Nishikawa; C. Managit; J. Wong; S. Kawakami; F. Yamashita; M. Hashida Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: Effect of lipid composition Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: effect of lipid composition. Targeting efficiency of galactosylated liposomes to hepatocytes in vivo: Effect of lipid composition Pharmaceutical Research, 19, 12, 1808-1814 Pharmaceutical research, 19, 12, 1808-1814 Pharmaceutical Research, 19, 12, 1808-1814 2002/12 Refereed English Disclose to all
F. Yamashita; S. Wanchana; M. Hashida Yamashita F, Wanchana S, Hashida M F. Yamashita; S. Wanchana; M. Hashida Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method. Quantitative structure/property relationship analysis of Caco-2 permeability using a genetic algorithm-based partial least squares method Journal of Pharmaceutical Sciences, 91, 10, 2230-2239 Journal of pharmaceutical sciences, 91, 10, 2230-2239 Journal of Pharmaceutical Sciences, 91, 10, 2230-2239 2002/10 Refereed English Disclose to all
K. Nakanishi; Y. Watanabe; M. Maruyama; F. Yamashita; Y. Takakura; M. Hashida Nakanishi K, Watanabe Y, Maruyama M, Yamashita F, Takakura Y, Hashida M K. Nakanishi; Y. Watanabe; M. Maruyama; F. Yamashita; Y. Takakura; M. Hashida Secretion polarity of interferon-β in epithelial cell lines Secretion polarity of interferon-beta in epithelial cell lines. Secretion polarity of interferon-β in epithelial cell lines Archives of Biochemistry and Biophysics, 402, 2, 201-207 Archives of biochemistry and biophysics, 402, 2, 201-207 Archives of Biochemistry and Biophysics, 402, 2, 201-207 2002/06 Refereed English Disclose to all
M. Nishikawa; A. Tamada; H. Kumai; F. Yamashita; M. Hashida Nishikawa M, Tamada A, Kumai H, Yamashita F, Hashida M M. Nishikawa; A. Tamada; H. Kumai; F. Yamashita; M. Hashida Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice International Journal of Cancer, 99, 3, 474-479 International journal of cancer, 99, 3, 474-479 International Journal of Cancer, 99, 3, 474-479 2002/05 Refereed English Disclose to all
Y. Yamasaki; K. Sumimoto; M. Nishikawa; F. Yamashita; K. Yamaoka; M. Hashida; Y. Takakura Yamasaki Y, Sumimoto K, Nishikawa M, Yamashita F, Yamaoka K, Hashida M, Takakura Y Y. Yamasaki; K. Sumimoto; M. Nishikawa; F. Yamashita; K. Yamaoka; M. Hashida; Y. Takakura Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: Importance of molecular size and negative charge density for in vivo recognition by receptors Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: importance of molecular size and negative charge density for in vivo recognition by receptors. Pharmacokinetic analysis of in vivo disposition of succinylated proteins targeted to liver nonparenchymal cells via scavenger receptors: Importance of molecular size and negative charge density for in vivo recognition by receptors Journal of Pharmacology and Experimental Therapeutics, 301, 2, 467-477 The Journal of pharmacology and experimental therapeutics, 301, 2, 467-477 Journal of Pharmacology and Experimental Therapeutics, 301, 2, 467-477 2002/05 Refereed English Disclose to all
S.-I. Fujiwara; F. Yamashita; M. Hashida Fujiwara S, Yamashita F, Hashida M S.-I. Fujiwara; F. Yamashita; M. Hashida Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network. Prediction of Caco-2 cell permeability using a combination of MO-calculation and neural network International Journal of Pharmaceutics, 237, 1-2, 95-105 International journal of pharmaceutics, 237, 1-2, 95-105 International Journal of Pharmaceutics, 237, 1-2, 95-105 2002/04 Refereed English Disclose to all
P. Opanasopit; M. Sakai; M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Opanasopit P, Sakai M, Nishikawa M, Kawakami S, Yamashita F, Hashida M P. Opanasopit; M. Sakai; M. Nishikawa; S. Kawakami; F. Yamashita; M. Hashida Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers. Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers Journal of Controlled Release, 80, 1-3, 283-294 Journal of controlled release : official journal of the Controlled Release Society, 80, 1-3, 283-294 Journal of Controlled Release, 80, 1-3, 283-294 2002/04 Refereed English Disclose to all
M. Nishikawa; S. Hasegawa; F. Yamashita; Y. Takakura; M. Hashida Nishikawa M, Hasegawa S, Yamashita F, Takakura Y, Hashida M M. Nishikawa; S. Hasegawa; F. Yamashita; Y. Takakura; M. Hashida Electrical charge on protein regulates its absorption from the rat small intestine Electrical charge on protein regulates its absorption from the rat small intestine. Electrical charge on protein regulates its absorption from the rat small intestine American Journal of Physiology - Gastrointestinal and Liver Physiology, 282, 4, G711-9 American journal of physiology. Gastrointestinal and liver physiology, 282, 4, G711-9 American Journal of Physiology - Gastrointestinal and Liver Physiology, 282, 4, G711-9 2002/04 Refereed English Disclose to all
Y. Takakura; M. Nishikawa; F. Yamashita; M. Hashida Takakura Y, Nishikawa M, Yamashita F, Hashida M Y. Takakura; M. Nishikawa; F. Yamashita; M. Hashida Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery. Influence of physicochemical properties on pharmacokinetics of non-viral vectors for gene delivery Journal of Drug Targeting, 10, 2, 99-104 Journal of drug targeting, 10, 2, 99-104 Journal of Drug Targeting, 10, 2, 99-104 2002/03 Refereed English Disclose to all
C.W. Lim; S.-I. Fujiwara; F. Yamashita; M. Hashida Lim CW, Fujiwara S, Yamashita F, Hashida M C.W. Lim; S.-I. Fujiwara; F. Yamashita; M. Hashida Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network. Prediction of human skin permeability using a combination of molecular orbital calculations and artificial neural network Biological and Pharmaceutical Bulletin, 25, 3, 361-366 Biological & pharmaceutical bulletin, 25, 3, 361-366 Biological and Pharmaceutical Bulletin, 25, 3, 361-366 2002/03 Refereed English Disclose to all
F. Yamashita; S.-I. Fujiwara; M. Hashida Yamashita F, Fujiwara S, Hashida M F. Yamashita; S.-I. Fujiwara; M. Hashida The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratorically variable Caco-2 permeability The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratory variable Caco-2 permeability. The "latent membrane permeability" concept: QSPR analysis of inter/intralaboratorically variable Caco-2 permeability Journal of Chemical Information and Computer Sciences, 42, 2, 408-413 Journal of chemical information and computer sciences, 42, 2, 408-413 Journal of Chemical Information and Computer Sciences, 42, 2, 408-413 2002/03 Refereed English Disclose to all
M. Hashida; F. Yamashita; K. Nishida; J. Nakamura Kawakami S, Yamashita F, Nishida K, Nakamura J, Hashida M M. Hashida; F. Yamashita; K. Nishida; J. Nakamura Glycosylated cationic liposomes for cell-selective gene delivery Glycosylated cationic liposomes for cell-selective gene delivery. Glycosylated cationic liposomes for cell-selective gene delivery Critical Reviews in Therapeutic Drug Carrier Systems, 19, 2, 171-190 Critical reviews in therapeutic drug carrier systems, 19, 2, 171-190 Critical Reviews in Therapeutic Drug Carrier Systems, 19, 2, 171-190 2002 Refereed English Disclose to all
K. Un; Y. Kono; M. Yoshida; F. Yamashita; S. Kawakami; M. Hashida K. Un; Y. Kono; M. Yoshida; F. Yamashita; S. Kawakami; M. Hashida Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes Pharmazie, 67, 5, 400-405 , 67, 5, 400-405 Pharmazie, 67, 5, 400-405 2012/05 Refereed English Disclose to all
P. Charoensit; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida P. Charoensit; S. Kawakami; Y. Higuchi; F. Yamashita; M. Hashida Enhanced growth inhibition of metastatic lung tumors by intravenous injection of ATRA-cationic liposome/IL-12 pDNA complexes in mice Enhanced growth inhibition of metastatic lung tumors by intravenous injection of ATRA-cationic liposome/IL-12 pDNA complexes in mice Cancer Gene Therapy, 17, 7, 512-522 , 17, 7, 512-522 Cancer Gene Therapy, 17, 7, 512-522 2010/07 Refereed English Disclose to all
F. Yamashita; T. Itoh; S. Yoshida; M.K. Haidar; M. Hashida F. Yamashita; T. Itoh; S. Yoshida; M.K. Haidar; M. Hashida A novel multi-dimensional visualization technique for understanding the design parameters of drug formulations A novel multi-dimensional visualization technique for understanding the design parameters of drug formulations Computers and Chemical Engineering, 34, 8, 1306-1311 , 34, 8, 1306-1311 Computers and Chemical Engineering, 34, 8, 1306-1311 2010 Refereed English Disclose to all
S. Kawakami; F. Yamashita; M. Hashida S. Kawakami; F. Yamashita; M. Hashida Liposomal In vivo Gene Delivery Liposomal In vivo Gene Delivery Modern Biopharmaceuticals: Design, Development and Optimization, 4, 1507-1519 , 4, 1507-1519 Modern Biopharmaceuticals: Design, Development and Optimization, 4, 1507-1519 2008 Refereed English Disclose to all
S.-F. Ma; M. Nishikawa; K. Hyoudou; R. Takahashi; M. Ikemura; Y. Kobayashi; F. Yamashita; M. Hashida S.-F. Ma; M. Nishikawa; K. Hyoudou; R. Takahashi; M. Ikemura; Y. Kobayashi; F. Yamashita; M. Hashida Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity Kidney International, 72, 12, 1474-1482 , 72, 12, 1474-1482 Kidney International, 72, 12, 1474-1482 2007 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Y. Higuchi; S. Kawakami; M. Nishikawa; F. Yamashita; M. Hashida Erratum: Intracellular distribution of NFκB decoy and its inhibitory effect on TNFα production by LPS stimulated RAW 264.7 cells (Journal of Controlled Release (2005) 107 (373-382) DOI: 10.1016/j.jconrel.2005.07.004) Erratum: Intracellular distribution of NFκB decoy and its inhibitory effect on TNFα production by LPS stimulated RAW 264.7 cells (Journal of Controlled Release (2005) 107 (373-382) DOI: 10.1016/j.jconrel.2005.07.004) Journal of Controlled Release, 111, 3, 390- , 111, 3, 390- Journal of Controlled Release, 111, 3, 390- 2006 Refereed English Disclose to all
W. Yeeprae; S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida W. Yeeprae; S. Kawakami; S. Suzuki; F. Yamashita; M. Hashida Physicochemical and pharmacokinetic characteristics of cationic liposomes Physicochemical and pharmacokinetic characteristics of cationic liposomes Pharmazie, 61, 2, 102-105 , 61, 2, 102-105 Pharmazie, 61, 2, 102-105 2006 Refereed English Disclose to all
Y. Higuchi; S. Kawakami; M. Oka; F. Yamashita; M. Hashida Y. Higuchi; S. Kawakami; M. Oka; F. Yamashita; M. Hashida Suppression of TNFα production in LPS induced liver failure in mice after intravenous injection of cationic liposomes/NFκB decoy complex Suppression of TNFα production in LPS induced liver failure in mice after intravenous injection of cationic liposomes/NFκB decoy complex Pharmazie, 61, 2, 144-147 , 61, 2, 144-147 Pharmazie, 61, 2, 144-147 2006 Refereed English Disclose to all
M. Sakai; M. Nishikawa; O. Thanaketpaisarn; F. Yamashita; M. Hashida M. Sakai; M. Nishikawa; O. Thanaketpaisarn; F. Yamashita; M. Hashida Hepatocyte-targeted gene transfer by combination of vascularly delivered plasmid DNA and in vivo electroporation Hepatocyte-targeted gene transfer by combination of vascularly delivered plasmid DNA and in vivo electroporation Gene Therapy, 12, 7, 607-616 , 12, 7, 607-616 Gene Therapy, 12, 7, 607-616 2005 Refereed English Disclose to all
S. Kawakami; F. Yamashita; M. Hashida S. Kawakami; F. Yamashita; M. Hashida Cell-selective delivery of gene and nucleic acid using glycosylated cationic liposomes Cell-selective delivery of gene and nucleic acid using glycosylated cationic liposomes Polymer Preprints, Japan, 54, 2, 5171-5172 , 54, 2, 5171-5172 Polymer Preprints, Japan, 54, 2, 5171-5172 2005 Refereed English Disclose to all
S. Kawakami; Y. Hattori; Y. Lu; Y. Higuchi; F. Yamashita; M. Hashida S. Kawakami; Y. Hattori; Y. Lu; Y. Higuchi; F. Yamashita; M. Hashida Effect of cationic charge on receptor-mediated transfection using mannosylated cationic liposome/plasmid DNA complexes following the intravenous administration in mice Effect of cationic charge on receptor-mediated transfection using mannosylated cationic liposome/plasmid DNA complexes following the intravenous administration in mice Pharmazie, 59, 5, 405-408 , 59, 5, 405-408 Pharmazie, 59, 5, 405-408 2004 Refereed English Disclose to all
P. Opanasopit; M. Nishikawa; C. Managit; F. Yamashita; M. Hashida P. Opanasopit; M. Nishikawa; C. Managit; F. Yamashita; M. Hashida Control of hepatic disposition of mannosylated liposomes by PEGylation: Effect of the molecular weight of PEG and the density of PEG and mannose Control of hepatic disposition of mannosylated liposomes by PEGylation: Effect of the molecular weight of PEG and the density of PEG and mannose S.T.P. Pharma Sciences, 13, 1, 57-62 , 13, 1, 57-62 S.T.P. Pharma Sciences, 13, 1, 57-62 2003/01 Refereed English Disclose to all
F. Yamashita; K. Takayama F. Yamashita; K. Takayama Artificial neural network modeling for pharmaceutical research Artificial neural network modeling for pharmaceutical research Advanced Drug Delivery Reviews, 55, 9, 1117- , 55, 9, 1117- Advanced Drug Delivery Reviews, 55, 9, 1117- 2003 Refereed English Disclose to all
P. Opanasopit; K. Hyoudou; M. Nishikawa; F. Yamashita; M. Hashida P. Opanasopit; K. Hyoudou; M. Nishikawa; F. Yamashita; M. Hashida Serum mannan binding protein inhibits mannosylated liposome-mediated transfection to macrophages Serum mannan binding protein inhibits mannosylated liposome-mediated transfection to macrophages Biochimica et Biophysica Acta - General Subjects, 1570, 3, 203-209 , 1570, 3, 203-209 Biochimica et Biophysica Acta - General Subjects, 1570, 3, 203-209 2002/04/15 Refereed English Disclose to all
F. Sakurai; T. Terada; K. Yasuda; F. Yamashita; Y. Takakura; M. Hashida F. Sakurai; T. Terada; K. Yasuda; F. Yamashita; Y. Takakura; M. Hashida The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes Gene Therapy, 9, 16, 1120-1126 , 9, 16, 1120-1126 Gene Therapy, 9, 16, 1120-1126 2002 Refereed English Disclose to all
M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura Cell-specific delivery of genes with glycosylated carriers Cell-specific delivery of genes with glycosylated carriers Advanced Drug Delivery Reviews, 52, 3, 187-196 , 52, 3, 187-196 Advanced Drug Delivery Reviews, 52, 3, 187-196 2001/11/19 Refereed English Disclose to all
Y. Imamura; K. Shimizu; F. Yamashita; K. Yamaoka; Y. Takakura; M. Hashida Y. Imamura; K. Shimizu; F. Yamashita; K. Yamaoka; Y. Takakura; M. Hashida Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers Biological and Pharmaceutical Bulletin, 24, 8, 930-934 , 24, 8, 930-934 Biological and Pharmaceutical Bulletin, 24, 8, 930-934 2001/08 Refereed English Disclose to all
Y. Takakura; M. Nishikawa; F. Yamashita; M. Hashida Y. Takakura; M. Nishikawa; F. Yamashita; M. Hashida Development of gene drug delivery systems based on pharmacokinetic studies Development of gene drug delivery systems based on pharmacokinetic studies European Journal of Pharmaceutical Sciences, 13, 1, 71-76 , 13, 1, 71-76 European Journal of Pharmaceutical Sciences, 13, 1, 71-76 2001/04 Refereed English Disclose to all
P. Opanasopit; Y. Higuchi; S. Kawakami; F. Yamashita; M. Nishikawa; M. Hashida P. Opanasopit; Y. Higuchi; S. Kawakami; F. Yamashita; M. Nishikawa; M. Hashida Involvement of serum mannan binding proteins and mannose receptors in uptake of mannosylated liposomes by macrophages Involvement of serum mannan binding proteins and mannose receptors in uptake of mannosylated liposomes by macrophages Biochimica et Biophysica Acta - Biomembranes, 1511, 1, 134-145 , 1511, 1, 134-145 Biochimica et Biophysica Acta - Biomembranes, 1511, 1, 134-145 2001/03/09 Refereed English Disclose to all
S. Kawakami; C. Munakata; S. Fumoto; F. Yamashita; M. Hashida S. Kawakami; C. Munakata; S. Fumoto; F. Yamashita; M. Hashida Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs Journal of Pharmaceutical Sciences, 90, 2, 105-113 , 90, 2, 105-113 Journal of Pharmaceutical Sciences, 90, 2, 105-113 2001/02 Refereed English Disclose to all
T. Sakaeda; N. Okamura; S. Nagata; T. Yagami; M. Horinouchi; K. Okumura; F. Yamashita; M. Hashida T. Sakaeda; N. Okamura; S. Nagata; T. Yagami; M. Horinouchi; K. Okumura; F. Yamashita; M. Hashida Molecular and pharmacokinetic properties of 222 commercially available oral drugs in humans Molecular and pharmacokinetic properties of 222 commercially available oral drugs in humans Biological and Pharmaceutical Bulletin, 24, 8, 935-940 , 24, 8, 935-940 Biological and Pharmaceutical Bulletin, 24, 8, 935-940 2001 Refereed English Disclose to all
F. Sakurai; T. Nishioka; F. Yamashita; Y. Takakura; M. Hashida F. Sakurai; T. Nishioka; F. Yamashita; Y. Takakura; M. Hashida Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system European Journal of Pharmaceutics and Biopharmaceutics, 52, 2, 165-172 , 52, 2, 165-172 European Journal of Pharmaceutics and Biopharmaceutics, 52, 2, 165-172 2001 Refereed English Disclose to all
F. Sakurai; T. Nishioka; H. Saito; T. Baba; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida F. Sakurai; T. Nishioka; H. Saito; T. Baba; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: The role of the neutral helper lipid Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: The role of the neutral helper lipid Gene Therapy, 8, 9, 677-686 , 8, 9, 677-686 Gene Therapy, 8, 9, 677-686 2001 Refereed English Disclose to all
A. Sato; S. Kawakami; M. Yamada; F. Yamashita; M. Hashida A. Sato; S. Kawakami; M. Yamada; F. Yamashita; M. Hashida Enhanced gene transfection in macrophages using mannosylated cationic liposome-polyethylenimine-plasmid DNA complexes Enhanced gene transfection in macrophages using mannosylated cationic liposome-polyethylenimine-plasmid DNA complexes Journal of Drug Targeting, 9, 3, 201-207 , 9, 3, 201-207 Journal of Drug Targeting, 9, 3, 201-207 2001 Refereed English Disclose to all
P. Opanasopit; K. Shirashi; M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida P. Opanasopit; K. Shirashi; M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein In vivo recognition of mannosylated proteins by hepatic mannose receptors and mannan-binding protein American Journal of Physiology - Gastrointestinal and Liver Physiology, 280, 5 43-5, G879-G889 , 280, 5 43-5, G879-G889 American Journal of Physiology - Gastrointestinal and Liver Physiology, 280, 5 43-5, G879-G889 2001 Refereed English Disclose to all
S. Kawakami; A. Sato; M. Yamada; F. Yamashita; M. Hashida S. Kawakami; A. Sato; M. Yamada; F. Yamashita; M. Hashida The effect of lipid composition on receptor-mediated in vivo gene transfection using mannosylated cationic liposomes in mice The effect of lipid composition on receptor-mediated in vivo gene transfection using mannosylated cationic liposomes in mice S.T.P. Pharma Sciences, 11, 1, 117-120 , 11, 1, 117-120 S.T.P. Pharma Sciences, 11, 1, 117-120 2001 Refereed English Disclose to all
P. Opanasopit; M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida P. Opanasopit; M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells Journal of Drug Targeting, 9, 5, 341-351 , 9, 5, 341-351 Journal of Drug Targeting, 9, 5, 341-351 2001 Refereed English Disclose to all
S. Kawakami; J. Wong; A. Sato; Y. Hattori; F. Yamashita; M. Hashida S. Kawakami; J. Wong; A. Sato; Y. Hattori; F. Yamashita; M. Hashida Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice Biochimica et Biophysica Acta - General Subjects, 1524, 2-3, 258-265 , 1524, 2-3, 258-265 Biochimica et Biophysica Acta - General Subjects, 1524, 2-3, 258-265 2000/12/15 Refereed English Disclose to all
F. Sakurai; R. Inoue; Y. Nishino; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida F. Sakurai; R. Inoue; Y. Nishino; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression Journal of Controlled Release, 66, 2-3, 255-269 , 66, 2-3, 255-269 Journal of Controlled Release, 66, 2-3, 255-269 2000/05/15 Refereed English Disclose to all
S. Nakajima; Y. Koshino; T. Nomura; F. Yamashita; S. Agrawal; Y. Takakura; M. Hashida S. Nakajima; Y. Koshino; T. Nomura; F. Yamashita; S. Agrawal; Y. Takakura; M. Hashida Intratumoral pharmacokinetics of oligonucleotides in a tissue-isolated tumor perfusion system Intratumoral pharmacokinetics of oligonucleotides in a tissue-isolated tumor perfusion system Antisense and Nucleic Acid Drug Development, 10, 2, 105-110 , 10, 2, 105-110 Antisense and Nucleic Acid Drug Development, 10, 2, 105-110 2000/04 Refereed English Disclose to all
S. Kawakami; S. Fumoto; M. Nishikawa; F. Yamashita; M. Hashida S. Kawakami; S. Fumoto; M. Nishikawa; F. Yamashita; M. Hashida In vivo gene delivery to the liver using novel galactosylated cationic liposomes In vivo gene delivery to the liver using novel galactosylated cationic liposomes Pharmaceutical Research, 17, 3, 306-313 , 17, 3, 306-313 Pharmaceutical Research, 17, 3, 306-313 2000/03 Refereed English Disclose to all
M. Hashida; K. Akamatsu; M. Nishikawa; F. Yamashita; H. Yoshikawa; Y. Takakura M. Hashida; K. Akamatsu; M. Nishikawa; F. Yamashita; H. Yoshikawa; Y. Takakura Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting Design of polymeric prodrugs of PGE1 for cell-specific hepatic targeting Pharmazie, 55, 3, 202-205 , 55, 3, 202-205 Pharmazie, 55, 3, 202-205 2000/03 Refereed English Disclose to all
S. Kawakami; A. Sato; M. Nishikawa; F. Yamashita; M. Hashida S. Kawakami; A. Sato; M. Nishikawa; F. Yamashita; M. Hashida Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes Gene Therapy, 7, 4, 292-299 , 7, 4, 292-299 Gene Therapy, 7, 4, 292-299 2000/02 Refereed English Disclose to all
F. Sakurai; R. Inoue; Y. Nishino; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida F. Sakurai; R. Inoue; Y. Nishino; A. Okuda; O. Matsumoto; T. Taga; F. Yamashita; Y. Takakura; M. Hashida Erratum: Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (Journal of Controlled Release 66 (2000) (255-269) Erratum: Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression (Journal of Controlled Release 66 (2000) (255-269) Journal of Controlled Release, 69, 1, 219-220 , 69, 1, 219-220 Journal of Controlled Release, 69, 1, 219-220 2000 Refereed English Disclose to all
Y. Hattori; S. Kawakami; F. Yamashita; M. Hashida Y. Hattori; S. Kawakami; F. Yamashita; M. Hashida Controlled biodistribution of galactosylated liposomes and incorporated probucol in hepatocyte-selective drug targeting Controlled biodistribution of galactosylated liposomes and incorporated probucol in hepatocyte-selective drug targeting Journal of Controlled Release, 69, 3, 369-377 , 69, 3, 369-377 Journal of Controlled Release, 69, 3, 369-377 2000 Refereed English Disclose to all
S. Kawakami; F. Yamashita; M. Hashida S. Kawakami; F. Yamashita; M. Hashida Disposition characteristics of emulsions and incorporated drugs after systemic or local injection Disposition characteristics of emulsions and incorporated drugs after systemic or local injection Advanced Drug Delivery Reviews, 45, 1, 77-88 , 45, 1, 77-88 Advanced Drug Delivery Reviews, 45, 1, 77-88 2000 Refereed English Disclose to all
M. Nishikawa; S. Takemura; F. Yamashita; Y. Takakura; D.K.F. Meijer; M. Hashida; P.J. Swart M. Nishikawa; S. Takemura; F. Yamashita; Y. Takakura; D.K.F. Meijer; M. Hashida; P.J. Swart Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice Pharmacokinetics and in vivo gene transfer of plasmid DNA complexed with mannosylated poly(L-lysine) in mice Journal of Drug Targeting, 8, 1, 29-38 , 8, 1, 29-38 Journal of Drug Targeting, 8, 1, 29-38 2000 Refereed English Disclose to all
S. Kawakami; C. Munakata; S. Fumoto; F. Yamashita; M. Hashida S. Kawakami; C. Munakata; S. Fumoto; F. Yamashita; M. Hashida Targeted delivery of prostaglandin E<sub>1</sub> to hepatocytes using galactosylated liposomes Targeted delivery of prostaglandin E<sub>1</sub> to hepatocytes using galactosylated liposomes Journal of Drug Targeting, 8, 3, 137-142 , 8, 3, 137-142 Journal of Drug Targeting, 8, 3, 137-142 2000 Refereed English Disclose to all
S. Harada; Y. Takahashi; H. Nakagawa; F. Yamashita; M. Hashida S. Harada; Y. Takahashi; H. Nakagawa; F. Yamashita; M. Hashida Effect of vehicle properties on skin penetration of emedastine Effect of vehicle properties on skin penetration of emedastine Biological and Pharmaceutical Bulletin, 23, 10, 1224-1228 , 23, 10, 1224-1228 Biological and Pharmaceutical Bulletin, 23, 10, 1224-1228 2000 Refereed English Disclose to all
Y. Matsukawa; H. Yamahara; F. Yamashita; V.H.L. Lee; E.D. Crandall; K.-J. Kim Y. Matsukawa; H. Yamahara; F. Yamashita; V.H.L. Lee; E.D. Crandall; K.-J. Kim Rates of protein transport across rat alveolar epithelial cell monolayers Rates of protein transport across rat alveolar epithelial cell monolayers Journal of Drug Targeting, 7, 5, 335-342 , 7, 5, 335-342 Journal of Drug Targeting, 7, 5, 335-342 2000 Refereed English Disclose to all
T. Takagi; M. Hashiguchi; T. Hiramatsu; F. Yamashita; Y. Takakura; M. Hashida T. Takagi; M. Hashiguchi; T. Hiramatsu; F. Yamashita; Y. Takakura; M. Hashida Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Effect of cationic liposomes on intracellular trafficking and efficacy of antisense oligonucleotides in mouse peritoneal macrophages Journal of Drug Targeting, 7, 5, 363-371 , 7, 5, 363-371 Journal of Drug Targeting, 7, 5, 363-371 2000 Refereed English Disclose to all
M. Hashida; K. Akamatsu; M. Nishikawa; F. Yamashita; Y. Takakura M. Hashida; K. Akamatsu; M. Nishikawa; F. Yamashita; Y. Takakura Design of polymeric prodrugs of prostaglandin E<sub>1</sub> having galactose residue for hepatocyte targeting Design of polymeric prodrugs of prostaglandin E<sub>1</sub> having galactose residue for hepatocyte targeting Journal of Controlled Release, 62, 1-2, 253-262 , 62, 1-2, 253-262 Journal of Controlled Release, 62, 1-2, 253-262 1999/11/01 Refereed English Disclose to all
N. Yamamura; Y. Magata; F. Yamashita; M. Hashida; H. Saji N. Yamamura; Y. Magata; F. Yamashita; M. Hashida; H. Saji Pharmacokinetic analysis of <sup>123</sup>I-labeled medium chain fatty acid as a radiopharmaceutical for hepatic function based on beta-oxidation Pharmacokinetic analysis of <sup>123</sup>I-labeled medium chain fatty acid as a radiopharmaceutical for hepatic function based on beta-oxidation Annals of Nuclear Medicine, 13, 4, 235-239 , 13, 4, 235-239 Annals of Nuclear Medicine, 13, 4, 235-239 1999/08 Refereed English Disclose to all
Y. Takakura; T. Takagi; M. Hashiguchi; M. Nishikawa; F. Yamashita; T. Doi; T. Imanishi; H. Suzuki; T. Kodama; M. Hashida Y. Takakura; T. Takagi; M. Hashiguchi; M. Nishikawa; F. Yamashita; T. Doi; T. Imanishi; H. Suzuki; T. Kodama; M. Hashida Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class A scavenger receptor knockout mice Characterization of plasmid DNA binding and uptake by peritoneal macrophages from class A scavenger receptor knockout mice Pharmaceutical Research, 16, 4, 503-508 , 16, 4, 503-508 Pharmaceutical Research, 16, 4, 503-508 1999/04 Refereed English Disclose to all
S. Okamoto; K. Nakanishi; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida S. Okamoto; K. Nakanishi; Y. Watanabe; F. Yamashita; Y. Takakura; M. Hashida Stimulation side-dependent asymmetrical secretion of poly I:poly C-induced interferon-β from polarized epithelial cell lines Stimulation side-dependent asymmetrical secretion of poly I:poly C-induced interferon-β from polarized epithelial cell lines Biochemical and Biophysical Research Communications, 254, 1, 5-9 , 254, 1, 5-9 Biochemical and Biophysical Research Communications, 254, 1, 5-9 1999/01/08 Refereed English Disclose to all
J. Shen; K.J. Elbert; F. Yamashita; C.-M. Lehr; K.-J Kim; V.H.L. Lee J. Shen; K.J. Elbert; F. Yamashita; C.-M. Lehr; K.-J Kim; V.H.L. Lee Organic cation transport in rabbit alveolar epithelial cell monolayers Organic cation transport in rabbit alveolar epithelial cell monolayers Pharmaceutical Research, 16, 8, 1280-1287 , 16, 8, 1280-1287 Pharmaceutical Research, 16, 8, 1280-1287 1999 Refereed English Disclose to all
N. Seko; H. Bando; C.L. Lim; F. Yamashita; M. Hashida N. Seko; H. Bando; C.L. Lim; F. Yamashita; M. Hashida Theoretical analysis of the effect of cutaneous metabolism on skin permeation of parabens based on a two-layer skin diffusion/metabolism model Theoretical analysis of the effect of cutaneous metabolism on skin permeation of parabens based on a two-layer skin diffusion/metabolism model Biological and Pharmaceutical Bulletin, 22, 3, 281-287 , 22, 3, 281-287 Biological and Pharmaceutical Bulletin, 22, 3, 281-287 1999 Refereed English Disclose to all
Mitsuru Hashida; Makiya Nishikawa; Fumiyoshi Yamashita; Yoshinobu Takakura Mitsuru Hashida; Makiya Nishikawa; Fumiyoshi Yamashita; Yoshinobu Takakura Cell specific targeting of drugs and genes with glycosylated liposomes Cell specific targeting of drugs and genes with glycosylated liposomes American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 40, 1, 297-298 , 40, 1, 297-298 American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 40, 1, 297-298 1999 Refereed English Disclose to all
X. Wu; F. Yamashita; M. Hashida X. Wu; F. Yamashita; M. Hashida Deconvolution analysis for absorption and metabolism of aspirin in microcapsules Deconvolution analysis for absorption and metabolism of aspirin in microcapsules Biological and Pharmaceutical Bulletin, 22, 11, 1212-1216 , 22, 11, 1212-1216 Biological and Pharmaceutical Bulletin, 22, 11, 1212-1216 1999 Refereed English Disclose to all
S. Kawakami; F. Yamashita; M. Nishikawa; Y. Takakura; M. Hashida S. Kawakami; F. Yamashita; M. Nishikawa; Y. Takakura; M. Hashida Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes Biochemical and Biophysical Research Communications, 252, 1, 78-83 , 252, 1, 78-83 Biochemical and Biophysical Research Communications, 252, 1, 78-83 1998/11/09 Refereed English Disclose to all
T. Nomura; N. Koreeda; F. Yamashita; Y. Takakura; M. Hashida T. Nomura; N. Koreeda; F. Yamashita; Y. Takakura; M. Hashida Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors Pharmaceutical Research, 15, 1, 128-132 , 15, 1, 128-132 Pharmaceutical Research, 15, 1, 128-132 1998/01 Refereed English Disclose to all
F. Yamashita; K.-J. Kim; V.H.L. Lee F. Yamashita; K.-J. Kim; V.H.L. Lee Dipeptide uptake and transport characteristics in rabbit tracheal epithelial cell layers cultured at an air interface Dipeptide uptake and transport characteristics in rabbit tracheal epithelial cell layers cultured at an air interface Pharmaceutical Research, 15, 7, 979-983 , 15, 7, 979-983 Pharmaceutical Research, 15, 7, 979-983 1998 Refereed English Disclose to all
T. Nomura; A. Saikawa; S. Morita; T. Sakaeda; F. Yamashita; K. Honda; Yoshinobu Takakura; M. Hashida T. Nomura; A. Saikawa; S. Morita; T. Sakaeda; F. Yamashita; K. Honda; Yoshinobu Takakura; M. Hashida Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection Journal of Controlled Release, 52, 3, 239-252 , 52, 3, 239-252 Journal of Controlled Release, 52, 3, 239-252 1998 Refereed English Disclose to all
T. Takino; N. Koreeda; T. Nomura; T. Sakaeda; F. Yamashita; Y. Takakura; M. Hashida T. Takino; N. Koreeda; T. Nomura; T. Sakaeda; F. Yamashita; Y. Takakura; M. Hashida Control of plasma cholesterol-lowering action of probucol with various lipid carrier systems Control of plasma cholesterol-lowering action of probucol with various lipid carrier systems Biological and Pharmaceutical Bulletin, 21, 5, 492-497 , 21, 5, 492-497 Biological and Pharmaceutical Bulletin, 21, 5, 492-497 1998 Refereed English Disclose to all
F. Yamashita; K.-J. Kim; V.H.L. Lee F. Yamashita; K.-J. Kim; V.H.L. Lee Gly-L-Phe transport and metabolism across primary cultured rabbit tracheal epithelial cell monolayers Gly-L-Phe transport and metabolism across primary cultured rabbit tracheal epithelial cell monolayers Pharmaceutical Research, 14, 2, 238-240 , 14, 2, 238-240 Pharmaceutical Research, 14, 2, 238-240 1997 Refereed English Disclose to all
H. Furitsu; K.-I. Ogawara; T. Fujita; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida H. Furitsu; K.-I. Ogawara; T. Fujita; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida Pharmacokinetic analysis of scavenger receptor-mediated uptake of anionized proteins in the isolated perfused rat liver Pharmacokinetic analysis of scavenger receptor-mediated uptake of anionized proteins in the isolated perfused rat liver International Journal of Pharmaceutics, 151, 1, 15-26 , 151, 1, 15-26 International Journal of Pharmaceutics, 151, 1, 15-26 1997 Refereed English Disclose to all
H. Bando; S. Mohri; F. Yamashita; Y. Takakura; M. Hashida H. Bando; S. Mohri; F. Yamashita; Y. Takakura; M. Hashida Effects of skin metabolism on percutaneous penetration of lipophilic drugs Effects of skin metabolism on percutaneous penetration of lipophilic drugs Journal of Pharmaceutical Sciences, 86, 6, 759-761 , 86, 6, 759-761 Journal of Pharmaceutical Sciences, 86, 6, 759-761 1997 Refereed English Disclose to all
H. Bando; M. Sahashi; F. Yamashita; Y. Takakura; M. Hashida H. Bando; M. Sahashi; F. Yamashita; Y. Takakura; M. Hashida In vivo evaluation of acyclovir prodrug penetration and metabolism through rat skin using a diffusion/bioconversion model In vivo evaluation of acyclovir prodrug penetration and metabolism through rat skin using a diffusion/bioconversion model Pharmaceutical Research, 14, 1, 56-62 , 14, 1, 56-62 Pharmaceutical Research, 14, 1, 56-62 1997 Refereed English Disclose to all
T. Nomura; S. Nakajima; K. Kawabata; F. Yamashita; Y. Takakura; M. Hashida T. Nomura; S. Nakajima; K. Kawabata; F. Yamashita; Y. Takakura; M. Hashida Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer Cancer Research, 57, 13, 2681-2686 , 57, 13, 2681-2686 Cancer Research, 57, 13, 2681-2686 1997 Refereed English Disclose to all
A. Saikawa; T. Nomura; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida A. Saikawa; T. Nomura; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida Pharmacokinetic analysis of drug disposition after intratumoral injection in a tissue-isolated tumor perfusion system Pharmacokinetic analysis of drug disposition after intratumoral injection in a tissue-isolated tumor perfusion system Pharmaceutical Research, 13, 10, 1438-1444 , 13, 10, 1438-1444 Pharmaceutical Research, 13, 10, 1438-1444 1996/10 Refereed English Disclose to all
H. Bando; T. Takagi; F. Yamashita; Y. Takakura; M. Hashida H. Bando; T. Takagi; F. Yamashita; Y. Takakura; M. Hashida Theoretical design of prodrug-enhancer combination based on a skin diffusion model: Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one Theoretical design of prodrug-enhancer combination based on a skin diffusion model: Prediction of permeation of acyclovir prodrugs treated with 1-geranylazacycloheptan-2-one Pharmaceutical Research, 13, 3, 427-432 , 13, 3, 427-432 Pharmaceutical Research, 13, 3, 427-432 1996/03 Refereed English Disclose to all
P.U. Jani; T. Nomura; F. Yamashita; Y. Takakura; A.T. Florence; M. Hashida P.U. Jani; T. Nomura; F. Yamashita; Y. Takakura; A.T. Florence; M. Hashida Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male Wistar rats Journal of Drug Targeting, 4, 2, 87-93 , 4, 2, 87-93 Journal of Drug Targeting, 4, 2, 87-93 1996 Refereed English Disclose to all
H. Bando; M. Sahashi; S. Mohri; F. Yamashita; Y. Takakura; M. Hashida H. Bando; M. Sahashi; S. Mohri; F. Yamashita; Y. Takakura; M. Hashida In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination International Journal of Pharmaceutics, 145, 1-2, 103-113 , 145, 1-2, 103-113 International Journal of Pharmaceutics, 145, 1-2, 103-113 1996 Refereed English Disclose to all
N.R. Mathias; F. Yamashita; V.H.L. Lee N.R. Mathias; F. Yamashita; V.H.L. Lee Respiratory epithelial cell culture models for evaluation of ion and drug transport Respiratory epithelial cell culture models for evaluation of ion and drug transport Advanced Drug Delivery Reviews, 22, 1-2, 215-249 , 22, 1-2, 215-249 Advanced Drug Delivery Reviews, 22, 1-2, 215-249 1996 Refereed English Disclose to all
H. Bando; M. Sahashi; T. Takagi; F. Yamashita; Y. Takakura; M. Hashida H. Bando; M. Sahashi; T. Takagi; F. Yamashita; Y. Takakura; M. Hashida Analysis of in vitro skin penetration of acyclovir prodrugs based on a diffusion model with a metabolic process Analysis of in vitro skin penetration of acyclovir prodrugs based on a diffusion model with a metabolic process International Journal of Pharmaceutics, 135, 1-2, 91-102 , 135, 1-2, 91-102 International Journal of Pharmaceutics, 135, 1-2, 91-102 1996 Refereed English Disclose to all
F. Yamashita; Y. Koyama; m. Kitano; Y. Takakura; M. Hashida F. Yamashita; Y. Koyama; m. Kitano; Y. Takakura; M. Hashida Analysis of in vivo skin penetration enhancement by oleic acid based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum Analysis of in vivo skin penetration enhancement by oleic acid based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum International Journal of Pharmaceutics, 117, 2, 173-179 , 117, 2, 173-179 International Journal of Pharmaceutics, 117, 2, 173-179 1995 Refereed English Disclose to all
T. Takino; E. Nagahama; T. Sakaeda(neeKakutani); F. Yamashita; Y. Takakura; M. Hashida T. Takino; E. Nagahama; T. Sakaeda(neeKakutani); F. Yamashita; Y. Takakura; M. Hashida Pharmacokinetic disposition analysis of lipophilic drugs injected with various lipid carriers in the single-pass rat liver perfusion system Pharmacokinetic disposition analysis of lipophilic drugs injected with various lipid carriers in the single-pass rat liver perfusion system International Journal of Pharmaceutics, 114, 1, 43-54 , 114, 1, 43-54 International Journal of Pharmaceutics, 114, 1, 43-54 1995 Refereed English Disclose to all
M. Nishikawa; C. Miyazaki; F. Yamashita; Y. Takakura; M. Hashida M. Nishikawa; C. Miyazaki; F. Yamashita; Y. Takakura; M. Hashida Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties American Journal of Physiology - Gastrointestinal and Liver Physiology, 268, 5 31-5, G849-G856 , 268, 5 31-5, G849-G856 American Journal of Physiology - Gastrointestinal and Liver Physiology, 268, 5 31-5, G849-G856 1995 Refereed English Disclose to all
F. Yamashita; H. Bando; Y. Takakura; M. Hashida F. Yamashita; H. Bando; Y. Takakura; M. Hashida A deconvolution method for estimating the first-pass metabolism of orally administered drugs A deconvolution method for estimating the first-pass metabolism of orally administered drugs Biological and Pharmaceutical Bulletin, 18, 12, 1787-1789 , 18, 12, 1787-1789 Biological and Pharmaceutical Bulletin, 18, 12, 1787-1789 1995 Refereed English Disclose to all
F. Yamashita; H. Bando; Y. Koyama; S. Kitagawa; Y. Takakura; M. Hashida F. Yamashita; H. Bando; Y. Koyama; S. Kitagawa; Y. Takakura; M. Hashida In vivo and in vitro analysis of skin penetration enhancement based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum In vivo and in vitro analysis of skin penetration enhancement based on a two-layer diffusion model with polar and nonpolar routes in the stratum corneum Pharmaceutical Research, 11, 2, 185-191 , 11, 2, 185-191 Pharmaceutical Research, 11, 2, 185-191 1994 Refereed English Disclose to all
Y. Koyama; H. Bando; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida Y. Koyama; H. Bando; F. Yamashita; Y. Takakura; H. Sezaki; M. Hashida Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model Comparative analysis of percutaneous absorption enhancement by d-limonene and oleic acid based on a skin diffusion model Pharmaceutical Research, 11, 3, 377-383 , 11, 3, 377-383 Pharmaceutical Research, 11, 3, 377-383 1994 Refereed English Disclose to all
M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura Targeting delivery of protein drugs by chemical modification Targeting delivery of protein drugs by chemical modification Drug Development and Industrial Pharmacy, 20, 4, 581-590 , 20, 4, 581-590 Drug Development and Industrial Pharmacy, 20, 4, 581-590 1994 Refereed English Disclose to all
F. Yamashita; T. Yoshioka; Y. Koyama; H. Okamoto; H. Sezaki; M. Hashida F. Yamashita; T. Yoshioka; Y. Koyama; H. Okamoto; H. Sezaki; M. Hashida Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum: Dose- dependent effect of 1-geranylazacycloheptan-2-one on drugs with different lipophilicities Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum: Dose- dependent effect of 1-geranylazacycloheptan-2-one on drugs with different lipophilicities Biological and Pharmaceutical Bulletin, 16, 7, 690-697 , 16, 7, 690-697 Biological and Pharmaceutical Bulletin, 16, 7, 690-697 1993/07 Refereed English Disclose to all
F. Yamashita; Y. Koyama; H. Sezaki; M. Hashida F. Yamashita; Y. Koyama; H. Sezaki; M. Hashida Estimation of a concentration profile of acyclovir in the skin after topical administration Estimation of a concentration profile of acyclovir in the skin after topical administration International Journal of Pharmaceutics, 89, 3, 199-206 , 89, 3, 199-206 International Journal of Pharmaceutics, 89, 3, 199-206 1993/02/05 Refereed English Disclose to all
M. Nishikawa; Y. Ohtsubo; J. Ohno; T. Fujita; Y. Koyama; F. Yamashita; M. Hashida; H. Sezaki M. Nishikawa; Y. Ohtsubo; J. Ohno; T. Fujita; Y. Koyama; F. Yamashita; M. Hashida; H. Sezaki Pharmacokinetics of receptor-mediated hepatic uptake of glycosylated albumin in mice Pharmacokinetics of receptor-mediated hepatic uptake of glycosylated albumin in mice International Journal of Pharmaceutics, 85, 1-3, 75-85 , 85, 1-3, 75-85 International Journal of Pharmaceutics, 85, 1-3, 75-85 1992/09/20 Refereed English Disclose to all
M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida; H. Sezaki M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida; H. Sezaki Demonstration of the receptor-mediated hepatic uptake of dextran in mice Demonstration of the receptor-mediated hepatic uptake of dextran in mice Journal of Pharmacy and Pharmacology, 44, 5, 396-401 , 44, 5, 396-401 Journal of Pharmacy and Pharmacology, 44, 5, 396-401 1992/05 Refereed English Disclose to all
K. Nishida; T. Takino; Y. Eguchi; F. Yamashita; M. Hashida; H. Sezaki K. Nishida; T. Takino; Y. Eguchi; F. Yamashita; M. Hashida; H. Sezaki Pharmacokinetic analysis of uptake process of lactosaminated albumin in rat liver constant infusion experiments Pharmacokinetic analysis of uptake process of lactosaminated albumin in rat liver constant infusion experiments International Journal of Pharmaceutics, 80, 2-3, 101-108 , 80, 2-3, 101-108 International Journal of Pharmaceutics, 80, 2-3, 101-108 1992/02/25 Refereed English Disclose to all
H. Okamoto; F. Yamashita; K. Saito; M. Hashida H. Okamoto; F. Yamashita; K. Saito; M. Hashida Analysis of drug penetration through the skin by the two-layer skin model Analysis of drug penetration through the skin by the two-layer skin model Pharmaceutical Research, 6, 11, 931-937 , 6, 11, 931-937 Pharmaceutical Research, 6, 11, 931-937 1989 Refereed English Disclose to all

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Title language:
Misc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yamashita F Yamashita F Yamashita F [Dynamic Simulation of Drug-Drug Interactions by Using Multi-level Physiological Modeling &amp; Simulation Platforms]. [Dynamic Simulation of Drug-Drug Interactions by Using Multi-level Physiological Modeling &amp; Simulation Platforms]. [Dynamic Simulation of Drug-Drug Interactions by Using Multi-level Physiological Modeling &amp; Simulation Platforms]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 138, 3, 347-351 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 138, 3, 347-351 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 138, 3, 347-351 2018 Refereed Disclose to all
Abdalkader R, Kawakami S, Unga J, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M Abdalkader R, Kawakami S, Unga J, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M The development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection. The development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection. The development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection. Drug delivery, 24, 1, 320-327 Drug delivery, 24, 1, 320-327 Drug delivery, 24, 1, 320-327 2017/11 Refereed Disclose to all
E. Miyako; T. Deguchi; Y. Nakajima; M. Yudasaka; Y. Hagihara; M. Horie; M. Shichiri; Y. Higuchi; F. Yamashita; M. Hashida; Y. Shigeri; Y. Yoshida; S. Iijima E. Miyako; T. Deguchi; Y. Nakajima; M. Yudasaka; Y. Hagihara; M. Horie; M. Shichiri; Y. Higuchi; F. Yamashita; M. Hashida; Y. Shigeri; Y. Yoshida; S. Iijima Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns Proceedings of the National Academy of Sciences of the United States of America, 109, 19, 7523-7528 , 109, 19, 7523-7528 Proceedings of the National Academy of Sciences of the United States of America, 109, 19, 7523-7528 2012/05/08 Refereed English Disclose to all
M. Yamazawa; T. Itoh; F. Yamashita M. Yamazawa; T. Itoh; F. Yamashita Visualization and level-of-detail control for multi-dimensional bioactive chemical data Visualization and level-of-detail control for multi-dimensional bioactive chemical data Proceedings of the International Conference on Information Visualisation, 11-16 , 11-16 Proceedings of the International Conference on Information Visualisation, 11-16 2008 Refereed English Disclose to all
T. Itoh; F. Yamashita T. Itoh; F. Yamashita Visualization of multi-dimensional data of bioactive chemicals using a hierarchical data visualization technique "heiankyoview Visualization of multi-dimensional data of bioactive chemicals using a hierarchical data visualization technique "heiankyoview Conferences in Research and Practice in Information Technology Series, 60, 23-29 , 60, 23-29 Conferences in Research and Practice in Information Technology Series, 60, 23-29 2006 Refereed English Disclose to all
M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura M. Hashida; M. Nishikawa; F. Yamashita; Y. Takakura Cell-specific targeting of drugs and genes with glycosylated liposomes: Comparison with glycosylated poly(amino acids) Cell-specific targeting of drugs and genes with glycosylated liposomes: Comparison with glycosylated poly(amino acids) ACS Symposium Series, 752, 201-211 , 752, 201-211 ACS Symposium Series, 752, 201-211 2000 Refereed English Disclose to all
M. Matsuki; F. Yamashita; A. Ishida-Yamamoto; K. Yamada; C. Kinoshita; S. Fushiki; E. Ueda; Y. Morishima; K. Tabata; H. Yasuno; M. Hashida; H. Iizuka; M. Ikawa; M. Okabe; G. Kondoh; T. Kinoshita; J. Takeda; K. Yamanishi M. Matsuki; F. Yamashita; A. Ishida-Yamamoto; K. Yamada; C. Kinoshita; S. Fushiki; E. Ueda; Y. Morishima; K. Tabata; H. Yasuno; M. Hashida; H. Iizuka; M. Ikawa; M. Okabe; G. Kondoh; T. Kinoshita; J. Takeda; K. Yamanishi Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) Proceedings of the National Academy of Sciences of the United States of America, 95, 3, 1044-1049 , 95, 3, 1044-1049 Proceedings of the National Academy of Sciences of the United States of America, 95, 3, 1044-1049 1998/02/03 Refereed English Disclose to all
H. Bando; M. Sahashi; F. Yamashita; Y. Takakura; M. Hashida H. Bando; M. Sahashi; F. Yamashita; Y. Takakura; M. Hashida Analysis of in vivo skin penetration enhancement by prodrug-enhancer combination based on a diffusion/bioconversion model Analysis of in vivo skin penetration enhancement by prodrug-enhancer combination based on a diffusion/bioconversion model Proceedings of the Controlled Release Society, 23, 277-278 , 23, 277-278 Proceedings of the Controlled Release Society, 23, 277-278 1996 Refereed English Disclose to all
S. Harada; Y. Takahashi; H. Nakagawa; F. Yamashita; M. Hashida S. Harada; Y. Takahashi; H. Nakagawa; F. Yamashita; M. Hashida Characterization of vehicle for skin penetration of emedastine with solubility parameter Characterization of vehicle for skin penetration of emedastine with solubility parameter Proceedings of the Controlled Release Society, 23, 311-312 , 23, 311-312 Proceedings of the Controlled Release Society, 23, 311-312 1996 Refereed English Disclose to all
T. Nomura; F. Yamashita; Y. Takakura; N. Hashida T. Nomura; F. Yamashita; Y. Takakura; N. Hashida Pharmacokinetic analysis of various lipid carrier systems after intratumoral injection in tissue-isolated tumors Pharmacokinetic analysis of various lipid carrier systems after intratumoral injection in tissue-isolated tumors Proceedings of the Controlled Release Society, 22, 420-421 , 22, 420-421 Proceedings of the Controlled Release Society, 22, 420-421 1995 Refereed English Disclose to all
M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida M. Nishikawa; F. Yamashita; Y. Takakura; M. Hashida Molecular design of protein derivatives targeted to the liver via the asialoglycoprotein receptor Molecular design of protein derivatives targeted to the liver via the asialoglycoprotein receptor Proceedings of the Controlled Release Society, 22, 502-503 , 22, 502-503 Proceedings of the Controlled Release Society, 22, 502-503 1995 Refereed English Disclose to all
F. Yamashita; Y. Koyama; Y. Takakura; M. Hashida F. Yamashita; Y. Koyama; Y. Takakura; M. Hashida Comparison of action mechanism of penetration enhancers based on a skin diffusion model Comparison of action mechanism of penetration enhancers based on a skin diffusion model Proceedings of the Controlled Release Society, 20, 424-425 , 20, 424-425 Proceedings of the Controlled Release Society, 20, 424-425 1993 Refereed English Disclose to all

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Title language:
Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Informatic Technologies for the Prediction of Pharmacokinetic Behaviors[Invited] Informatic Technologies for the Prediction of Pharmacokinetic Behaviors [Invited] Informatic Technologies for the Prediction of Pharmacokinetic Behaviors [Invited] 2018 International Conference of The Korean Society of Pharmaceutical Sciences and Technology 2018 International Conference of The Korean Society of Pharmaceutical Sciences and Technology 2018 International Conference of The Korean Society of Pharmaceutical Sciences and Technology 2018/11/22 English Oral presentation(invited, special) Disclose to all
Application of machine learning techniques to pharmacokinetic analysis[Invited] Application of machine learning techniques to pharmacokinetic analysis [Invited] Application of machine learning techniques to pharmacokinetic analysis [Invited] 13th France-Japan Drug Delivery System Symposium 13th France-Japan Drug Delivery System Symposium 13th France-Japan Drug Delivery System Symposium 2018/10/22 English Oral presentation(invited, special) Disclose to all
Curriculum towards training pharmacist scientists: Case in Kyoto University[Invited] Curriculum towards training pharmacist scientists: Case in Kyoto University [Invited] Curriculum towards training pharmacist scientists: Case in Kyoto University [Invited] The 7th Conference of Asia Pacific Pharmacy Education Network The 7th Conference of Asia Pacific Pharmacy Education Network The 7th Conference of Asia Pacific Pharmacy Education Network 2018/10/06 English Oral presentation(invited, special) Disclose to all
創薬テクノロジーとしてのDDS[Invited] 創薬テクノロジーとしてのDDS [Invited] 立命館大学創薬科学研究センター 創剤研究コンソーシアム・製剤技術研究コンソーシアム 2018年合同研究会 立命館大学創薬科学研究センター 創剤研究コンソーシアム・製剤技術研究コンソーシアム 2018年合同研究会 2018/08/24 Japanese Oral presentation(invited, special) Disclose to all
薬学系からみた最近のDDSのトピックと将来展望[Invited] 薬学系からみた最近のDDSのトピックと将来展望 [Invited] 第34回日本DDS学会学術集会 第34回日本DDS学会学術集会 2018/06/22 Japanese Oral presentation(invited, special) Disclose to all
Data mining technologies in accelerating ADME screening[Invited] Data mining technologies in accelerating ADME screening [Invited] Data mining technologies in accelerating ADME screening [Invited] The 5th Asian Symposium on Pharmaceutical Science and Technology & the 5th Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences The 5th Asian Symposium on Pharmaceutical Science and Technology & the 5th Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences The 5th Asian Symposium on Pharmaceutical Science and Technology & the 5th Enlarged Editorial Board Conference of the Asian Journal of Pharmaceutical Sciences 2018/05/09 English Oral presentation(invited, special) Disclose to all
Data mining and visualization techniques for ADME screening in early drug discovery[Invited] Data mining and visualization techniques for ADME screening in early drug discovery [Invited] Data mining and visualization techniques for ADME screening in early drug discovery [Invited] CUHK One-day Forum: Better, Safer, and Cheaper Medicine: A 21st Century Mandate CUHK One-day Forum: Better, Safer, and Cheaper Medicine: A 21st Century Mandate CUHK One-day Forum: Better, Safer, and Cheaper Medicine: A 21st Century Mandate 2017/11/04 English Oral presentation(invited, special) Disclose to all
多階層生体機能モデリング・シミュレーション環境を利用した薬物間相互作用の動的シミュレーション[Invited] 多階層生体機能モデリング・シミュレーション環境を利用した薬物間相互作用の動的シミュレーション [Invited] 日本薬学会第137年会 日本薬学会第137年会 2017/03/27 Japanese Oral presentation(invited, special) Disclose to all
In silico pharmacokinetics: from QSAR to system modeling[Invited] In silico pharmacokinetics: from QSAR to system modeling [Invited] In silico pharmacokinetics: from QSAR to system modeling [Invited] International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History 2017/03/09 English Oral presentation(invited, special) Disclose to all
多階層生体機能モデリング&シミュレーションプラットフォームを利用した薬物動態予測研究[Invited] 多階層生体機能モデリング&シミュレーションプラットフォームを利用した薬物動態予測研究 [Invited] 第378回CBI学会講演会 第378回CBI学会講演会 2016/12/08 Japanese Oral presentation(invited, special) Disclose to all
薬物相互作用のin silico予測 薬物相互作用のin silico予測 第37回日本臨床薬理学会学術総会 第37回日本臨床薬理学会学術総会 2016/12/02 Japanese Oral presentation(invited, special) Disclose to all
In silico techniques in drug formulation studies[Invited] 製剤研究のためのIn silico技術 [Invited] In silico techniques in drug formulation studies [Invited] 日本薬物動態学会第31年会 日本薬物動態学会第31年会 2016/10/15 Japanese Oral presentation(invited, special) Disclose to all
Use of informatics technologies for the prediction of pharmacokinetic behaviors[Invited] Use of informatics technologies for the prediction of pharmacokinetic behaviors [Invited] Use of informatics technologies for the prediction of pharmacokinetic behaviors [Invited] 12th France-Japan Drug Delivery System Symposium 12th France-Japan Drug Delivery System Symposium 12th France-Japan Drug Delivery System Symposium 2016/10/11 English Oral presentation(invited, special) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
浅井 義之、山下 富義 浅井 義之、山下 富義 Dr. 北野の0から始めるシステムバイオロジー Dr. 北野の0から始めるシステムバイオロジー 羊土社 羊土社 2015/04 Contributor Disclose to all
山下 富義 山下 富義 薬剤学実験法必携マニュアル 薬剤学実験法必携マニュアル 2014/04 Contributor Disclose to all
山下 富義 山下 富義 第7版化学便覧 応用化学編 第7版化学便覧 応用化学編 丸善 丸善 2014/01 Contributor Disclose to all
山下 富義 山下 富義 薬物の消化管吸収予測研究の最前線 薬物の消化管吸収予測研究の最前線 メディカルドゥ メディカルドゥ 2010 Contributor Disclose to all
山下 富義 山下 富義 分子薬物動態学 分子薬物動態学 南山堂 南山堂 2008 Contributor Disclose to all
山下 富義 山下 富義 インシリコ創薬科学 インシリコ創薬科学 京都廣川書店 京都廣川書店 2008 Contributor Disclose to all
山下 富義 山下 富義 我が国の保健医療の将来 20年後のヒューマンライフを展望する 我が国の保健医療の将来 20年後のヒューマンライフを展望する 財団法人ヒューマンサイエンス振興財団 財団法人ヒューマンサイエンス振興財団 2007 Contributor Disclose to all
山下 富義 山下 富義 創薬動態 医薬品創製のための考え方と最新情報 創薬動態 医薬品創製のための考え方と最新情報 日本薬物動態学会 日本薬物動態学会 2006 Contributor Disclose to all
山下 富義 山下 富義 ゲノム研究実験ハンドブック ゲノム研究実験ハンドブック 2004 Contributor Disclose to all
山下 富義 山下 富義 ドラッグデリバリーシステムの新展開-究極の薬物治療をめざして- ドラッグデリバリーシステムの新展開-究極の薬物治療をめざして- シーエムシー出版 シーエムシー出版 2004 Contributor Disclose to all
山下 富義 山下 富義 第6版 化学便覧 応用化学編Ⅱ 第6版 化学便覧 応用化学編Ⅱ 2003 Contributor Disclose to all
山下 富義 山下 富義 改訂 図解・夢の薬剤DDS 改訂 図解・夢の薬剤DDS 薬業時報社 薬業時報社 1997 Contributor Disclose to all
山下 富義 山下 富義 今日のDDS 薬物送達システム 今日のDDS 薬物送達システム 医薬ジャーナル社 医薬ジャーナル社 1997 Contributor Disclose to all
山下 富義 山下 富義 図解 夢の薬剤DDS 図解 夢の薬剤DDS 薬業時報社, 薬業時報社, 1991 Japanese Contributor Disclose to all
山下 富義 山下 富義 Terpenes as Penetration Enhancers Terpenes as Penetration Enhancers Percutaneous Penetration Enhancers,/,309-321 Percutaneous Penetration Enhancers,/,309-321 1995 English Disclose to all

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Title language:
Patents
Inventor(s) Inventor(s) (Japanese) Inventor(s) (English) Title Title(Japanese) Title(English) Stage Patent number Date Disclose
山下 富義 山下 富義 化合物群表示装置、化合物群表示方法、プログラム、及びコンピュータ読み取り可能な記録媒体 化合物群表示装置、化合物群表示方法、プログラム、及びコンピュータ読み取り可能な記録媒体 特許登録 特許第4280831号 2009/03/27 Disclose to all
伊藤 貴之, 山下 富義 伊藤 貴之, 山下 富義 データベースを可視化するための画像生成方法及びプログラム並びにデータベース表示装置 データベースを可視化するための画像生成方法及びプログラム並びにデータベース表示装置 特許公開 特開2008-299363 2008/12/11 Disclose to all
野間 昭典, 山下 富義, 竹内 綾子, 寺島 啓介 野間 昭典, 山下 富義, 竹内 綾子, 寺島 啓介 シミュレーション装置およびプログラム シミュレーション装置およびプログラム 特許公開 WO2006-057268 2006/06/01 Disclose to all
山下 富義, 伊藤 貴之 山下 富義, 伊藤 貴之 化合物群表示装置、化合物群表示方法、プログラム、及びコンピュータ読み取り可能な記録媒体 化合物群表示装置、化合物群表示方法、プログラム、及びコンピュータ読み取り可能な記録媒体 特許公開 特開2006-318048 2006/11/24 Disclose to all
Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
平成13年度日本薬剤学会旭化成製剤学奨励賞Asahi Kasei Pharmaceutics Young Investigator Award 日本薬剤学会 2001
日本薬物動態学会奨励賞 日本薬物動態学会 2003
日本薬学会薬学研究ビジョン部会賞 日本薬学会薬学研究ビジョン部会 2004
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
基盤研究(B) Representative 自然言語処理に基づく薬物代謝ネットワークと化合物間相互作用の網羅的情報解析 2009-2011
新学術領域研究(研究領域提案型) Representative 小分子-生体システム相互作用の分子階層における統合的解析 2011-2014
挑戦的萌芽研究 Representative ヘパリンナノ粒子の多重標的機能を巧妙に利用した画期的関節リウマチ炎治療法の開発 2011/04/28-2013/03/31
新学術領域研究 Representative 小分子-生体システム相互作用の分子階層における統合的解析 2011/07/21-2015/03/31
挑戦的萌芽研究 Representative 進化的アルゴリズムによるPopPKモデリングの完全自動化 2013-2014
挑戦的萌芽研究 Representative 進化的アルゴリズムによるPopPKモデリングの完全自動化 2013/04/01-2015/03/31
基盤研究(C) Representative 自己組織化ヘパリンナノ粒子が示す抗炎症作用のメカニズム 2015/04/01-2018/03/31
挑戦的萌芽研究 Representative 進化的アルゴリズムによるPopPKモデリングの完全自動化 (平成26年度分) 2014/04/01-2015/03/31
新学術領域研究(研究領域提案型) Representative 小分子-生体システム相互作用の分子階層における統合的解析 (平成26年度分) 2014/04/01-2015/03/31
基盤研究(C) Representative 自己組織化ヘパリンナノ粒子が示す抗炎症作用のメカニズム (平成27年度分) 2015/04/01-2016/03/31
基盤研究(C) Representative 自己組織化ヘパリンナノ粒子が示す抗炎症作用のメカニズム (平成28年度分) 2016/04/01-2017/03/31
創薬基盤推進研究事業 Representative 糖鎖認識多階層ナノDDS創成に関する研究 Development of multi-dimensionally glyco-targeted nano-DDSs 2017/05/-2020/03/31
基盤研究(C) Representative 自己組織化ヘパリンナノ粒子が示す抗炎症作用のメカニズム (平成29年度分) 2017/04/01-2018/03/31
基盤研究(B) Representative 逆行性輸送経路を介した小胞体への多元的薬物デリバリー (平成30年度分) 2018/04/01-2019/03/31

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Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
医療薬学I(薬剤学) 後期 薬学部 2011/04-2012/03
薬剤学1(溶液製剤論) 後期 薬学部 2011/04-2012/03
先端医療SGD演習 前期 薬学部 2011/04-2012/03
医療倫理実習 後期 薬学部 2011/04-2012/03
医療実務事前学習 後期前期 薬学部 2011/04-2012/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and 前期不定 薬学研究科 2011/04-2012/03
基盤医療薬科学実験技術(秋入学用) Basic Laboratory Techniques in Pharmacy and 後期不定 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and 通年不定 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学実習(秋入学用) Laboratory Practice in Basic Pharmacodynamic and 後期前期 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学実験(秋入学用) Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2011/04-2012/03
基盤薬品動態医療薬学演習(秋入学用) Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2011/04-2012/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2011/04-2012/03
薬学専門実習IV 後期 薬学部 2011/04-2012/03
薬学専門実習3 後期 薬学部 2011/04-2012/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2012/04-2013/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2012/04-2013/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2012/04-2013/03
医療薬学I(薬剤学) Medicinal Pharmacy I(Pharmaceutics) 後期 薬学部 2012/04-2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2012/04-2013/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2012/04-2013/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2012/04-2013/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2012/04-2013/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2012/04-2013/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2012/04-2013/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2012/04-2013/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2012/04-2013/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2012/04-2013/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2012/04-2013/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2012/04-2013/03
薬学専門実習III Pharmaceutical Laboratory III: Biochemistry and Microbiology 後期 薬学部 2012/04-2013/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2012/04-2013/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2012/04-2013/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2012/04-2013/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2012/04-2013/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2013/04-2014/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2013/04-2014/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2013/04-2014/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2013/04-2014/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2013/04-2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2013/04-2014/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2013/04-2014/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2013/04-2014/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2013/04-2014/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2013/04-2014/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2013/04-2014/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2013/04-2014/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2013/04-2014/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2013/04-2014/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2013/04-2014/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2013/04-2014/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2013/04-2014/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2013/04-2014/03
先端薬学論 Frontier in pharmaceutical science 後期不定 薬学研究科 2013/04-2014/03
薬と医療 Pharmaceuticals and Medicine 前期 全学共通科目 2013/04-2014/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2014/04-2015/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2014/04-2015/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2014/04-2015/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2014/04-2015/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2014/04-2015/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2014/04-2015/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2014/04-2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2014/04-2015/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2014/04-2015/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2014/04-2015/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2014/04-2015/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2014/04-2015/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2014/04-2015/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2014/04-2015/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2014/04-2015/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2014/04-2015/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2014/04-2015/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2014/04-2015/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2014/04-2015/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2014/04-2015/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2015/04-2016/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2015/04-2016/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2015/04-2016/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2015/04-2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2015/04-2016/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2015/04-2016/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2015/04-2016/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2015/04-2016/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2015/04-2016/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2015/04-2016/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2015/04-2016/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2015/04-2016/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2015/04-2016/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2015/04-2016/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2015/04-2016/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2015/04-2016/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2015/04-2016/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2015/04-2016/03
ILASセミナー ILAS Seminar 前期 全学共通科目 2016/04-2017/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2016/04-2017/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2016/04-2017/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2016/04-2017/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2016/04-2017/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2016/04-2017/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2016/04-2017/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期前期 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期前期 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期前期 薬学研究科 2016/04-2017/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2016/04-2017/03
基礎化学実験 Fundamental Chemical Experiments 前期 全学共通科目 2016/04-2017/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2016/04-2017/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2016/04-2017/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2016/04-2017/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2016/04-2017/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2016/04-2017/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2016/04-2017/03
薬学専門実習3 Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology 後期 薬学部 2016/04-2017/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2016/04-2017/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2016/04-2017/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2016/04-2017/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2016/04-2017/03
薬局方・薬事関連法規 Pharmacopoeia ; Pharmaceutical Laws 前期 薬学部 2016/04-2017/03
先端医療SGD演習 Frontier SGD Classes for Clinical Pharmacy 前期 薬学部 2017/04-2018/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2017/04-2018/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2017/04-2018/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期前期 薬学部 2017/04-2018/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2017/04-2018/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2017/04-2018/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2017/04-2018/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2017/04-2018/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2017/04-2018/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2017/04-2018/03
特別実習〔実践臨床薬学〕 Research Training(Education of Clinical Pharmacy) 通年 薬学部 2017/04-2018/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2017/04-2018/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2017/04-2018/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2017/04-2018/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2017/04-2018/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2017/04-2018/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2017/04-2018/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2017/04-2018/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2017/04-2018/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2017/04-2018/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2017/04-2018/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2017/04-2018/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2017/04-2018/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2017/04-2018/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2017/04-2018/03
共用試験関係 通年 薬学部 2018/04-2019/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2018/04-2019/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2018/04-2019/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2018/04-2019/03
国試連絡用 通年 薬学部 2018/04-2019/03
地域医療薬学2 Community Clinical Pharmacy2 前期 薬学部 2018/04-2019/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2018/04-2019/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2018/04-2019/03
基盤医療薬科学特論I Advanced Basic Pharmacy and Biomedicinal Sciences I 後期不定 薬学研究科 2018/04-2019/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2018/04-2019/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2018/04-2019/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2018/04-2019/03
多職種連携医療体験実習 Interprofessional Clinical Exposure 前期 薬学部 2018/04-2019/03
実務実習 通年 薬学部 2018/04-2019/03
特別実習〔実践臨床薬学〕 Research Training(Education of Clinical Pharmacy) 通年 薬学部 2018/04-2019/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2018/04-2019/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2018/04-2019/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2018/04-2019/03
臨床薬学概論 Introduction to Clinical Pharmacy 前期不定 薬学研究科 2018/04-2019/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2018/04-2019/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2018/04-2019/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2018/04-2019/03
臨床薬学特論 Advanced Clinical Pharmacy 後期不定 薬学研究科 2018/04-2019/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2018/04-2019/03
薬剤学1(溶液製剤論) Pharmaceutics 1 (Liquid Formulations) 後期 薬学部 2018/04-2019/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2018/04-2019/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 後期不定 薬学研究科 2018/04-2019/03
薬学研究SGD演習 SGD Classes for Pharmaceutical Research 前期 薬学部 2018/04-2019/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 後期前期 薬学研究科 2018/04-2019/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2018/04-2019/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 後期前期 薬学研究科 2018/04-2019/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 後期前期 薬学研究科 2018/04-2019/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2018/04-2019/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 後期前期 薬学研究科 2018/04-2019/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2018/04-2019/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2018/04-2019/03
薬物動態学 Biopharmaceutics 後期 工学研究科 2018/04-2019/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2018/04-2019/03
共用試験関係 通年 薬学部 2019/04-2020/03
創薬医療薬科学概論 Introduction to Pharmacy and Biomedical Sciences for Drug Discovery 前期不定 薬学研究科 2019/04-2020/03
医療倫理実習 Laboratory for medical ethics 後期 薬学部 2019/04-2020/03
医療実務事前学習 Pre-Training for Clinical Clerkship 後期 薬学部 2019/04-2020/03
医薬品開発プロジェクト演習II Pharmaceutical R&D Exercise II 前期 薬学部 2019/04-2020/03
国試連絡用 通年 薬学部 2019/04-2020/03
地域医療薬学2 Community Clinical Pharmacy2 前期 薬学部 2019/04-2020/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 前期不定 薬学研究科 2019/04-2020/03
基盤医療薬科学実験技術 Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences 後期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 前期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 後期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実習 Laboratory Practice in Basic Pharmacodynamic and Pharmacological Sciences 通年不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 前期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 後期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学実験 Research in Basic Pharmacology and Drug Delivery 通年不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 前期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 後期不定 薬学研究科 2019/04-2020/03
基盤薬品動態医療薬学演習 Basic Pharmacology and Drug Delivery Research Seminar 通年不定 薬学研究科 2019/04-2020/03
基礎臨床研究 Basic Clinical Research 後期 薬学部 2019/04-2020/03
多職種連携医療体験実習 Interprofessional Clinical Exposure 前期 薬学部 2019/04-2020/03
実務実習 通年 薬学部 2019/04-2020/03
特別実習〔実践臨床薬学〕 Research Training(Education of Clinical Pharmacy) 通年 薬学部 2019/04-2020/03
特別実習[薬品動態制御学] Research Training(Drug Delivery) 通年 薬学部 2019/04-2020/03
特別実習(薬品動態制御学) Research Training(Drug Delivery) 通年 薬学部 2019/04-2020/03
病院実務実習 Clinical Clerkship in Hospital Pharmacy 通年 薬学部 2019/04-2020/03
臨床薬学演習Ⅲ Seminar for Clinical Pharmacy III 通年不定 薬学研究科 2019/04-2020/03
臨床薬学演習Ⅱ Seminar for Clinical Pharmacy II 通年不定 薬学研究科 2019/04-2020/03
臨床薬学演習Ⅰ Seminar for Clinical Pharmacy I 通年不定 薬学研究科 2019/04-2020/03
臨床薬学総論 Introduction to Clinical Pharmacy 後期 薬学部 2019/04-2020/03
薬学実験技術 Basic Laboratory Techniques in Pharmaceutical Sciences 前期不定 薬学研究科 2019/04-2020/03
薬学研究SGD演習 SGD Classes for Pharmaceutical Research 前期 薬学部 2019/04-2020/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 前期不定 薬学研究科 2019/04-2020/03
薬学研究実習Ⅱ Laboratory Practice in Pharmaceutical Sciences II 通年不定 薬学研究科 2019/04-2020/03
薬学研究実習Ⅰ Laboratory Practice in Pharmaceutical Sciences I 通年不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 後期不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅲ Research in Pharmaceutical Sciences III 通年不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 前期不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅱ Research in Pharmaceutical Sciences II 通年不定 薬学研究科 2019/04-2020/03
薬学研究実験Ⅰ Research in Pharmaceutical Sciences I 通年不定 薬学研究科 2019/04-2020/03
薬局実務実習 Clinical Clerkship in Community Pharmacy 通年 薬学部 2019/04-2020/03
薬物動態学(LIMS) Biopharmaceutics (LIMS) 後期集中 医学研究科 2019/04-2020/03

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School management (title, position)
Title Period
発明評価委員会(ソフトウェア・コンテンツ分野拠点) 委員 2009/04/01-2010/03/31
京都大学国際交流センター外国人留学生日本語・日本文化研修委員会 委員 2009/09/20-2011/03/31
発明評価委員会(メディカル・バイオ分野拠点) 委員 2010/04/01-2011/03/31
外国人留学生日本語・日本文化研修委員会 委員 2011/04/01-2014/03/31
国際交流推進機構外国人留学生日本語・日本文化研修委員会 2013/09/19-2014/03/31
学生生活委員会委員 2018/04/01-2020/03/31
オープンキャンパス委員会 委員 2018/01/01-2018/12/31
情報環境機構教育システム運用委員会委員 2014/05/01-2016/03/31
吉田事業場衛生委員会委員(法人側委員) 2006/04/01-2008/03/31
情報環境機構教育用コンピューターシステム運用委員会委員 2015/04/01-2017/03/31
Faculty management (title, position)
Title Period
実務実習委員会 委員 2011/04/01-2013/03/31
実務実習委員会 委員 2014/04/01-
共用試験委員会 委員 2011/04/01-2013/03/31
共用試験委員会 委員 2014/04/01-
ホームページ広報委員会 委員長 2011/04/01-2012/03/31
ホームページ広報委員会 委員 2012/04/01-2013/03/31
ホームページ広報委員会 委員 2014/04/01-
統合薬学教育開発センター運営委員会 委員 2014/04/01-
図書委員会 委員 2011/04/01-2017/03/31
動物実験委員会 委員 2011/04/01-
環境・安全衛生委員会 委員 2011/04/01-2017/03/31
教務委員会 委員 2011/04/01-
衛生管理者 2015/04/01-
情報システム委員会 委員 2011/04/01-
建物・設備・機器管理運営委員会 委員 2011/04/01-
RI管理委員会 委員 2013/04/01-
学生委員(先任) 2018/04/01-2019/03/31
就職委員 2018/04/01-2019/03/31
情報セキュリティ委員会 委員 2011/04/01-

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Academic organizaions (other)
Organization name(Japanese) Organization name(English) Misc(Japanese) Misc(English) Period
日本薬学会 薬学教育委員会 2017/04/01-
日本薬学会 平成25年度改訂薬学教育モデル・コアカリキュラムの実施状況に関する調査・研究委員会 2018/11/01-2019/03/31
Other activities (awards)
Award name Organization name Date
日本薬剤学会旭化成製剤学奨励賞 日本薬剤学会 2001
日本薬物動態学会奨励賞 日本薬物動態学会 2003
日本薬学会薬学研究ビジョン部会賞 日本薬学会薬学研究ビジョン部会 2004
Other activities (private companies, NPOs, etc.)
Company name Activity Period
薬学共用試験センター 試験統括委員会委員 2018/4-