小島 洋児

Last Update: 2019/06/03 09:13:53

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Name(Kanji/Kana/Abecedarium Latinum)
小島 洋児/コジマ ヨウジ/Kojima, Yoji
Primary Affiliation(Org1/Job title)
iPS細胞研究所/Program-Specific Research Center Assistant Professor
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
博士(医学) 京都大学
Language of Instruction
Language(japanese) Language(english) Code
English
researchmap URL
https://researchmap.jp/7000009456
Research Topics
(Japanese)
生殖細胞の分化発生過程の解明
(English)
Differentiation and development of germ cell lineage
Fields of research (key words)
Key words(Japanese) Key words(English)
多能性、幹細胞、胚発生 Pluripotency, Stem cells, Embryo development
生殖細胞 Germ cell
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yamashiro C, Sasaki K, Yabuta Y,_Kojima_Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T,_Saitou_M. Yamashiro C, Sasaki K, Yabuta Y,_Kojima_Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T,_Saitou_M. Yamashiro C, Sasaki K, Yabuta Y,_Kojima_Y, Nakamura T, Okamoto I, Yokobayashi S, Murase Y, Ishikura Y, Shirane K, Sasaki H, Yamamoto T,_Saitou_M. Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Generation of human oogonia from induced pluripotent stem cells in vitro. Science, 362, 6412, 356-360 Science, 362, 6412, 356-360 Science, 362, 6412, 356-360 2018/10/19 Refereed English Disclose to all
Kojima, Y., Sasaki, K., Yokobayashi, S., Sakai, Y., Nakamura, T., Yabuta, Y., Nakaki, F., Nagaoka, S., Woltjen, K., Hotta, A., Yamamoto, T., and Saitou, M. Kojima, Y., Sasaki, K., Yokobayashi, S., Sakai, Y., Nakamura, T., Yabuta, Y., Nakaki, F., Nagaoka, S., Woltjen, K., Hotta, A., Yamamoto, T., and Saitou, M. Kojima, Y., Sasaki, K., Yokobayashi, S., Sakai, Y., Nakamura, T., Yabuta, Y., Nakaki, F., Nagaoka, S., Woltjen, K., Hotta, A., Yamamoto, T., and Saitou, M. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell Stem Cell, 21, 4, 517-532 Cell stem cell, 21, 4, 517-532 Cell Stem Cell, 21, 4, 517-532 2017/10/05 Refereed English Disclose to all
Kaufman-Francis K, Goh HN, Kojima Y, Studdert JB, Jones V, Power MD, Wilkie E, Teber E, Loebel DA, Tam PP Kaufman-Francis K, Goh HN, Kojima Y, Studdert JB, Jones V, Power MD, Wilkie E, Teber E, Loebel DA, Tam PP Kaufman-Francis K, Goh HN, Kojima Y, Studdert JB, Jones V, Power MD, Wilkie E, Teber E, Loebel DA, Tam PP Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo. Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo. Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 369, 1657 Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 369, 1657 Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 369, 1657 2014/12 Refereed Disclose to all
Kojima Y, Tam OH, Tam PP Kojima Y, Tam OH, Tam PP Kojima Y, Tam OH, Tam PP Timing of developmental events in the early mouse embryo. Timing of developmental events in the early mouse embryo. Timing of developmental events in the early mouse embryo. Seminars in cell & developmental biology, 34, 65-75 Seminars in cell & developmental biology, 34, 65-75 Seminars in cell & developmental biology, 34, 65-75 2014/10 Refereed Disclose to all
Y. Kojima; K. Kaufman-Francis; J.B. Studdert; K.A. Steiner; M.D. Power; D.A.F. Loebel; V. Jones; A. Hor; G. De Alencastro; G.J. Logan; E.T. Teber; O.H. Tam; M.D. Stutz; I.E. Alexander; H.A. Pickett; P.P.L. Tam Kojima Y, Kaufman-Francis K, Studdert JB, Steiner KA, Power MD, Loebel DA, Jones V, Hor A, de Alencastro G, Logan GJ, Teber ET, Tam OH, Stutz MD, Alexander IE, Pickett HA, Tam PP Y. Kojima; K. Kaufman-Francis; J.B. Studdert; K.A. Steiner; M.D. Power; D.A.F. Loebel; V. Jones; A. Hor; G. De Alencastro; G.J. Logan; E.T. Teber; O.H. Tam; M.D. Stutz; I.E. Alexander; H.A. Pickett; P.P.L. Tam The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak. The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak Cell Stem Cell, 14, 1, 107-120 Cell stem cell, 14, 1, 107-120 Cell Stem Cell, 14, 1, 107-120 2014/01 Refereed English Research paper(scientific journal) Disclose to all
S.S. Tanaka; Y. Kojima; Y.L. Yamaguchi; R. Nishinakamura; P.P.L. Tam Tanaka SS, Kojima Y, Yamaguchi YL, Nishinakamura R, Tam PP S.S. Tanaka; Y. Kojima; Y.L. Yamaguchi; R. Nishinakamura; P.P.L. Tam Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo. Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo Development Growth and Differentiation, 53, 7, 843-856 Development, growth & differentiation, 53, 7, 843-856 Development Growth and Differentiation, 53, 7, 843-856 2011/09 Refereed English Disclose to all
Y. Kuwabara; K. Ono; T. Horie; H. Nishi; K. Nagao; M. Kinoshita; S. Watanabe; O. Baba; Y. Kojima; S. Shizuta; M. Imai; T. Tamura; T. Kita; T. Kimura Kuwabara Y, Ono K, Horie T, Nishi H, Nagao K, Kinoshita M, Watanabe S, Baba O, Kojima Y, Shizuta S, Imai M, Tamura T, Kita T, Kimura T Y. Kuwabara; K. Ono; T. Horie; H. Nishi; K. Nagao; M. Kinoshita; S. Watanabe; O. Baba; Y. Kojima; S. Shizuta; M. Imai; T. Tamura; T. Kita; T. Kimura Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage. Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage Circulation: Cardiovascular Genetics, 4, 4, 446-454 Circulation. Cardiovascular genetics, 4, 4, 446-454 Circulation: Cardiovascular Genetics, 4, 4, 446-454 2011/08 Refereed English Disclose to all
Y. Nakashima; K. Ono; Y. Yoshida; Y. Kojima; T. Kita; M. Tanaka; T. Kimura Nakashima Y, Ono K, Yoshida Y, Kojima Y, Kita T, Tanaka M, Kimura T Y. Nakashima; K. Ono; Y. Yoshida; Y. Kojima; T. Kita; M. Tanaka; T. Kimura The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting. The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting Biochemical and Biophysical Research Communications, 390, 3, 821-826 Biochemical and biophysical research communications, 390, 3, 821-826 Biochemical and Biophysical Research Communications, 390, 3, 821-826 2009/12 Refereed English Disclose to all
Y. Kojima; K. Ono; K. Inoue; Y. Takagi; K.-i. Kikuta; M. Nishimura; Y. Yoshida; Y. Nakashima; H. Matsumae; Y. Furukawa; N. Mikuni; M. Nobuyoshi; T. Kimura; T. Kita; M. Tanaka Kojima Y, Ono K, Inoue K, Takagi Y, Kikuta K, Nishimura M, Yoshida Y, Nakashima Y, Matsumae H, Furukawa Y, Mikuni N, Nobuyoshi M, Kimura T, Kita T, Tanaka M Y. Kojima; K. Ono; K. Inoue; Y. Takagi; K.-i. Kikuta; M. Nishimura; Y. Yoshida; Y. Nakashima; H. Matsumae; Y. Furukawa; N. Mikuni; M. Nobuyoshi; T. Kimura; T. Kita; M. Tanaka Progranulin expression in advanced human atherosclerotic plaque Progranulin expression in advanced human atherosclerotic plaque. Progranulin expression in advanced human atherosclerotic plaque Atherosclerosis, 206, 1, 102-108 Atherosclerosis, 206, 1, 102-108 Atherosclerosis, 206, 1, 102-108 2009/09 Refereed English Disclose to all
H. Matsumae; Y. Yoshida; K. Ono; K. Togi; K. Inoue; Y. Furukawa; Y. Nakashima; Y. Kojima; M. Nobuyoshi; T. Kita; M. Tanaka Matsumae H, Yoshida Y, Ono K, Togi K, Inoue K, Furukawa Y, Nakashima Y, Kojima Y, Nobuyoshi M, Kita T, Tanaka M H. Matsumae; Y. Yoshida; K. Ono; K. Togi; K. Inoue; Y. Furukawa; Y. Nakashima; Y. Kojima; M. Nobuyoshi; T. Kita; M. Tanaka CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model. CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model Arteriosclerosis, Thrombosis, and Vascular Biology, 28, 6, 1077-1083 Arteriosclerosis, thrombosis, and vascular biology, 28, 6, 1077-1083 Arteriosclerosis, Thrombosis, and Vascular Biology, 28, 6, 1077-1083 2008/06 Refereed English Disclose to all
Y. Yoshida; K. Togi; H. Matsumae; Y. Nakashima; Y. Kojima; H. Yamamoto; K. Ono; T. Nakamura; T. Kita; M. Tanaka Yoshida Y, Togi K, Matsumae H, Nakashima Y, Kojima Y, Yamamoto H, Ono K, Nakamura T, Kita T, Tanaka M Y. Yoshida; K. Togi; H. Matsumae; Y. Nakashima; Y. Kojima; H. Yamamoto; K. Ono; T. Nakamura; T. Kita; M. Tanaka CCN1 protects cardiac myocytes from oxidative stress via β1 integrin-Akt pathway CCN1 protects cardiac myocytes from oxidative stress via beta1 integrin-Akt pathway. CCN1 protects cardiac myocytes from oxidative stress via β1 integrin-Akt pathway Biochemical and Biophysical Research Communications, 355, 3, 611-618 Biochemical and biophysical research communications, 355, 3, 611-618 Biochemical and Biophysical Research Communications, 355, 3, 611-618 2007/04 Refereed English Disclose to all

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Title language:
Misc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yoji Kojima 小島 洋児 Yoji Kojima Human Specific Molecular Mechanisms of Primordial Germ Cell Differentiation ヒト特異的な始原生殖細胞の運命決定機構 Human Specific Molecular Mechanisms of Primordial Germ Cell Differentiation The 39th Annual Meeting of the Molecular Biology Society of Japan 第39回日本分子生物学会年会 The 39th Annual Meeting of the Molecular Biology Society of Japan 2016/12 Refereed Japanese Disclose to all
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Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Evolutionarily Distinctive Mechanisms of Human Germ Cell Lineage Specification Evolutionarily Distinctive Mechanisms of Human Germ Cell Lineage Specification Evolutionarily Distinctive Mechanisms of Human Germ Cell Lineage Specification Annual Meeting of International Society for Stem Cell Research Annual Meeting of International Society for Stem Cell Research Annual Meeting of International Society for Stem Cell Research International Society for Stem Cell Research International Society for Stem Cell Research 2018/06/22 English Oral presentation(general) Disclose to all
Human Specific Molecular Mechanisms of Primordial Germ Cell Differentiation Human Specific Molecular Mechanisms of Primordial Germ Cell Differentiation Human Specific Molecular Mechanisms of Primordial Germ Cell Differentiation Annual Meeting of the Molecular Biology Society of Japan 日本分子生物学会年会 Annual Meeting of the Molecular Biology Society of Japan 日本分子生物学会 日本分子生物学会 2016/12/01 Japanese Oral presentation(general) Disclose to all
Characterisation of Epiblast Stem Cells (EpiSC) – Tool to understand gastrulation. Characterisation of Epiblast Stem Cells (EpiSC) – Tool to understand gastrulation. Characterisation of Epiblast Stem Cells (EpiSC) – Tool to understand gastrulation. CMRI seminar CMRI seminar CMRI seminar CMRI, Australia CMRI, Australia 2012/06/29 English Oral presentation(invited, special) Disclose to all
Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Annual Meeting of International Society for Stem Cell Research Annual Meeting of International Society for Stem Cell Research Annual Meeting of International Society for Stem Cell Research International Society for Stem Cell Research International Society for Stem Cell Research 2012/06/15 English Poster presentation Disclose to all
Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Characteristics of multipotent stem cells derived from the epiblast and ectoderm of post implantation mouse embryos Japanese Society of Developmental Biologists 46th and Japan Society for Cell Biology 日本発生生物学会年会 Japanese Society of Developmental Biologists 46th and Japan Society for Cell Biology 日本発生生物学会年会 日本発生生物学会年会 2012/05/31 English Poster presentation Disclose to all
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External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
基盤研究(C) Representative ヒトES/iPS細胞の多能性維持におけるPRDM14の作用機序の解明 (平成27年度分) 2015/04/01-2016/03/31
基盤研究(C) Representative ヒトES/iPS細胞の多能性維持におけるPRDM14の作用機序の解明 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(C) Representative ヒトES/iPS細胞の多能性維持におけるPRDM14の作用機序の解明 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(B) Assignment 網羅的ゲノム解析と生殖細胞発生機構の理解に基づく中枢神経系胚細胞腫発生機序の解明 2019/04/01-2022/03/31
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2015/04-2016/03