大石 真也

Last Update: 2018/06/28 07:45:09

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Name(Kanji/Kana/Abecedarium Latinum)
大石 真也/オオイシ シンヤ/Oishi, Shinya
Primary department(Org1/Job title)
Graduate Schools Pharmaceutical Sciences/Associate Professor
Faculty
Org1 Job title
薬学部
Contact address
Type Address(Japanese) Address(English)
Office 京都市左京区吉田下阿達町46-29 京都大学薬学研究科 Graduate School of Pharmaceutical Sciences, Sakyo-ku, Kyoto 606-8501, Japan
Phone
Type Number
Office 075-753-4561
E-mail address
E-mail address
soishi @ pharm.kyoto-u.ac.jp
Affiliated academic organization(s) (Japanese)
Organization name(Japanese) Organization name(English)
日本薬学会
日本化学会
日本ペプチド学会
有機合成化学協会
日本ケミカルバイオロジー学会
Affiliated academic organization(s) (overseas)
Organization name Country
American Chemical Society USA
Academic degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
修士(薬学) 京都大学 Kyoto University
博士(薬学) 京都大学 Kyoto University
Graduate school
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(Japanese) Major(English) Degree
京都大学 Kyoto University 大学院薬学研究科博士後期課程 Graduate School of Pharmaceutical Sciences 修了
京都大学 Kyoto University 大学院薬学研究科修士課程 Graduate School of Pharmaceutical Sciences 修了
University
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(s)(Japanese) Major(s)(English) Degree
京都大学 Kyoto University 薬学部薬学科 卒業
Highschool
Highschool Kana
静岡県立藤枝東高等学校 しずおかけんりつふじえだひがしこうとうがっこう
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
2003/04/-2004/05/ 米国NIH/NCI National Cancer Institute, NIH, USA 博士研究員 Visiting Fellow
2004/06/-2005/12/ 静岡県立大学大学院 薬学研究科・創薬探索センター Graduate School of Pharmaceutical Sciences, University of Shizuoka 講師 Lecturer
2006/01/-2007/03/ 京都大学大学院薬学研究科 Graduate School of Pharmaceutical Sciences, Kyoto University 助手 Assistant Professor
2007/04/-2009/05/ 京都大学大学院薬学研究科 Graduate School of Pharmaceutical Sciences, Kyoto University 助教 Assistant Professor
2009/06/-2015/09/ 京都大学大学院薬学研究科 Graduate School of Pharmaceutical Sciences, Kyoto University 講師 Lecturer
2015/10/- 京都大学 Kyoto University 准教授 Associate Professor
ORCID ID
orcid.org/0000-0002-2833-2539
Research Topics
(Japanese)
生体分子の生物活性・機能を活かした医薬品リード化合物の創製と医薬品探索技術の開発
(English)
Medicinal Chemistry of Peptides and the Related Biomolecules
Overview of your research
(Japanese)
ペプチドやタンパク質は、生体の機能調節に関わる生物活性物質として働くとともに、特定の構造をもとに機能を発揮する有する機能分子であることから、医薬品のリード化合物と医薬品の標的分子の2つの観点で重要な生体分子です。ペプチドの構造修飾により高活性・高機能性リガンドを創製したり、新たな機能を付したタンパク質の化学合成によりこれまでにない医薬品探索の方法の確立を目指した研究を展開しています。
(English)
Peptides and proteins play important roles to regulate the biological functions as bioactive substances and functional architectures. My research interests and goals include design and syntheses of novel bioactive and/or functional peptides, peptidomimetics and proteins, which are applicable to novel therapeutic lead compounds as well as unique drug discovery technologies.
Fields of research (key words)
Key words(Japanese) Key words(English)
医薬品化学 Medicinal Chemistry
生物有機化学 Bioorganic Chemistry
有機化学 Organic Chemistry
Fields of research (kaken code)
Kaken code
Drug development chemistry
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yuka Kobayashi, Masaru Hoshino, Tomoshi Kameda, Kazuya Kobayashi, Kenichi Akaji, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Yuka Kobayashi, Masaru Hoshino, Tomoshi Kameda, Kazuya Kobayashi, Kenichi Akaji, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Yuka Kobayashi, Masaru Hoshino, Tomoshi Kameda, Kazuya Kobayashi, Kenichi Akaji, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle Inorganic Chemistry Inorganic Chemistry Inorganic Chemistry 2018/05 Refereed English Disclose to all
Takumi Ohara, Masato Kaneda, Tomo Saito, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Takumi Ohara, Masato Kaneda, Tomo Saito, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Takumi Ohara, Masato Kaneda, Tomo Saito, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Head-to-tail macrocyclization of cysteine-free peptides using an o -aminoanilide linker Head-to-tail macrocyclization of cysteine-free peptides using an o -aminoanilide linker Head-to-tail macrocyclization of cysteine-free peptides using an o -aminoanilide linker Bioorganic & Medicinal Chemistry Letters, 28, 8, 1283 Bioorganic & Medicinal Chemistry Letters, 28, 8, 1283 Bioorganic & Medicinal Chemistry Letters, 28, 8, 1283 2018/05 Refereed Disclose to all
Haruka Sekiguchi, Tomoko Kuroyanagi, David Rhainds, Kazuya Kobayashi, Yuka Kobayashi, Hiroaki Ohno, Nikolaus Heveker, Kenichi Akaji, Nobutaka Fujii, Shinya Oishi Haruka Sekiguchi, Tomoko Kuroyanagi, David Rhainds, Kazuya Kobayashi, Yuka Kobayashi, Hiroaki Ohno, Nikolaus Heveker, Kenichi Akaji, Nobutaka Fujii, Shinya Oishi Haruka Sekiguchi, Tomoko Kuroyanagi, David Rhainds, Kazuya Kobayashi, Yuka Kobayashi, Hiroaki Ohno, Nikolaus Heveker, Kenichi Akaji, Nobutaka Fujii, Shinya Oishi Structure–Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3) Structure–Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3) Structure–Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3) Journal of Medicinal Chemistry, 61, 8, 3745 Journal of Medicinal Chemistry, 61, 8, 3745 Journal of Medicinal Chemistry, 61, 8, 3745 2018/04 Refereed Disclose to all
Masato Kaneda, Shinsaku Kawaguchi, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Masato Kaneda, Shinsaku Kawaguchi, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Masato Kaneda, Shinsaku Kawaguchi, Nobutaka Fujii, Hiroaki Ohno, Shinya Oishi Structure–Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide–Polyketides Structure–Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide–Polyketides Structure–Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide–Polyketides ACS Medicinal Chemistry Letters ACS Medicinal Chemistry Letters ACS Medicinal Chemistry Letters 2018/04 Refereed Disclose to all
Masato Kaneda, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Masato Kaneda, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Masato Kaneda, Shinsuke Inuki, Hiroaki Ohno, Shinya Oishi Total Synthesis and Stereochemical Revision of Stereocalpin A: Mirror-Image Approach for Stereochemical Assignments of the Peptide–Polyketide Macrocycle Total Synthesis and Stereochemical Revision of Stereocalpin A: Mirror-Image Approach for Stereochemical Assignments of the Peptide–Polyketide Macrocycle Total Synthesis and Stereochemical Revision of Stereocalpin A: Mirror-Image Approach for Stereochemical Assignments of the Peptide–Polyketide Macrocycle The Journal of Organic Chemistry The Journal of Organic Chemistry The Journal of Organic Chemistry 2018/03 Refereed Disclose to all
Shugo Tsuda, Masayoshi Mochizuki, Hiroyuki Ishiba, Kumiko Yoshizawa-Kumagaye, Hideki Nishio, Shinya Oishi, Taku Yoshiya Shugo Tsuda, Masayoshi Mochizuki, Hiroyuki Ishiba, Kumiko Yoshizawa-Kumagaye, Hideki Nishio, Shinya Oishi, Taku Yoshiya Shugo Tsuda, Masayoshi Mochizuki, Hiroyuki Ishiba, Kumiko Yoshizawa-Kumagaye, Hideki Nishio, Shinya Oishi, Taku Yoshiya Easy-to-Attach/Detach Solubilizing-Tag-Aided Chemical Synthesis of an Aggregative Capsid Protein Easy-to-Attach/Detach Solubilizing-Tag-Aided Chemical Synthesis of an Aggregative Capsid Protein Easy-to-Attach/Detach Solubilizing-Tag-Aided Chemical Synthesis of an Aggregative Capsid Protein Angewandte Chemie International Edition Angewandte Chemie International Edition Angewandte Chemie International Edition 2018/02 Refereed Disclose to all
Naoka Hamada, Yusuke Yoshida, Shinya Oishi, Hiroaki Ohno Naoka Hamada, Yusuke Yoshida, Shinya Oishi, Hiroaki Ohno Naoka Hamada, Yusuke Yoshida, Shinya Oishi, Hiroaki Ohno Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold Organic Letters, 19, 14, 3875 Organic Letters, 19, 14, 3875 Organic Letters, 19, 14, 3875 2017/07 Refereed Disclose to all
Junpei Matsuoka, Yuka Matsuda, Yuiki Kawada, Shinya Oishi, Hiroaki Ohno Junpei Matsuoka, Yuka Matsuda, Yuiki Kawada, Shinya Oishi, Hiroaki Ohno Junpei Matsuoka, Yuka Matsuda, Yuiki Kawada, Shinya Oishi, Hiroaki Ohno Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles Angewandte Chemie International Edition, 56, 26, 7444 Angewandte Chemie International Edition, 56, 26, 7444 Angewandte Chemie International Edition, 56, 26, 7444 2017/06 Refereed Disclose to all
Hiroyuki Ishiba, Taro Noguchi, Keitou Shu, Hiroaki Ohno, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Nobutaka Fujii, Shinya Oishi Hiroyuki Ishiba, Taro Noguchi, Keitou Shu, Hiroaki Ohno, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Nobutaka Fujii, Shinya Oishi Hiroyuki Ishiba, Taro Noguchi, Keitou Shu, Hiroaki Ohno, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Nobutaka Fujii, Shinya Oishi Investigation of the inhibitory mechanism of apomorphine against MDM2–p53 interaction Investigation of the inhibitory mechanism of apomorphine against MDM2–p53 interaction Investigation of the inhibitory mechanism of apomorphine against MDM2–p53 interaction Bioorganic {\&} Medicinal Chemistry Letters Bioorganic {\&} Medicinal Chemistry Letters Bioorganic {\&} Medicinal Chemistry Letters 2017/06 Refereed Disclose to all
Taro Noguchi, Hiroyuki Ishiba, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Hiroaki Ohno, Nobutaka Fujii, Shinya Oishi Taro Noguchi, Hiroyuki Ishiba, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Hiroaki Ohno, Nobutaka Fujii, Shinya Oishi Taro Noguchi, Hiroyuki Ishiba, Kaori Honda, Yasumitsu Kondoh, Hiroyuki Osada, Hiroaki Ohno, Nobutaka Fujii, Shinya Oishi Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems Bioconjugate Chemistry, 28, 2, 609 Bioconjugate Chemistry, 28, 2, 609 Bioconjugate Chemistry, 28, 2, 609 2017/02 Refereed Disclose to all
Jun-ichi Sawada, Ayumi Osawa, Tomoki Takeuchi, Masato Kaneda, Shinya Oishi, Nobutaka Fujii, Akira Asai, Keiji Tanino, Kosuke Namba Jun-ichi Sawada, Ayumi Osawa, Tomoki Takeuchi, Masato Kaneda, Shinya Oishi, Nobutaka Fujii, Akira Asai, Keiji Tanino, Kosuke Namba Jun-ichi Sawada, Ayumi Osawa, Tomoki Takeuchi, Masato Kaneda, Shinya Oishi, Nobutaka Fujii, Akira Asai, Keiji Tanino, Kosuke Namba Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP) Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP) Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP) Bioorganic {\&} Medicinal Chemistry Letters, 26, 23, 5765-5769 Bioorganic {\&} Medicinal Chemistry Letters, 26, 23, 5765-5769 Bioorganic {\&} Medicinal Chemistry Letters, 26, 23, 5765-5769 2016/12 Refereed Disclose to all
Yamamoto Koki, Okazaki Shiho, Ohno Hiroaki, Matsuda Fuko, Ohkura Satoshi, Maeda Kei-Ichiro, Fujii Nobutaka, Oishi Shinya Yamamoto Koki, Okazaki Shiho, Ohno Hiroaki, Matsuda Fuko, Ohkura Satoshi, Maeda Kei-Ichiro, Fujii Nobutaka, Oishi Shinya Yamamoto Koki, Okazaki Shiho, Ohno Hiroaki, Matsuda Fuko, Ohkura Satoshi, Maeda Kei-Ichiro, Fujii Nobutaka, Oishi Shinya Development of novel NK3 receptor antagonists with reduced environmental impact. Development of novel NK3 receptor antagonists with reduced environmental impact. Development of novel NK3 receptor antagonists with reduced environmental impact. Bioorganic & medicinal chemistry, 24, 16, 3500 Bioorganic & medicinal chemistry, 24, 16, 3500 Bioorganic & medicinal chemistry, 24, 16, 3500 2016 Refereed Disclose to all
Nishiyama Daisuke, Ohara Ayako, Chiba Hiroaki, Kumagai Hiroshi, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Nishiyama Daisuke, Ohara Ayako, Chiba Hiroaki, Kumagai Hiroshi, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Nishiyama Daisuke, Ohara Ayako, Chiba Hiroaki, Kumagai Hiroshi, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Formal Total Synthesis of (+/-)-Strictamine Based on a Gold-Catalyzed Cyclization Formal Total Synthesis of (+/-)-Strictamine Based on a Gold-Catalyzed Cyclization Formal Total Synthesis of (+/-)-Strictamine Based on a Gold-Catalyzed Cyclization Organic Letters, 18, 7, 1673 Organic Letters, 18, 7, 1673 Organic Letters, 18, 7, 1673 2016 Refereed Disclose to all
Oishi Shinya, Fujii Nobutaka Oishi Shinya, Fujii Nobutaka Oishi Shinya, Fujii Nobutaka Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands. Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands. Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands. Biopolymers, 588-597 Biopolymers, 588-597 Biopolymers, 588-597 2016 Refereed Disclose to all
Nishiyama Daisuke, Sakai Yuki, Sekiguchi Haruka, Chiba Hiroaki, Misu Ryosuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Nishiyama Daisuke, Sakai Yuki, Sekiguchi Haruka, Chiba Hiroaki, Misu Ryosuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Nishiyama Daisuke, Sakai Yuki, Sekiguchi Haruka, Chiba Hiroaki, Misu Ryosuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to kappa-Opioid Receptor Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to kappa-Opioid Receptor Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to kappa-Opioid Receptor Chemical & Pharmaceutical Bulletin, 64, 7, 1003 Chemical & Pharmaceutical Bulletin, 64, 7, 1003 Chemical & Pharmaceutical Bulletin, 64, 7, 1003 2016 Refereed Disclose to all
Kato Fumihiro, Ishida Yuki, Oishi Shinya, Fujii Nobutaka, Watanabe Satoru, Vasudevan Subhash G, Tajima Shigeru, Takasaki Tomohiko, Suzuki Youichi, Ichiyama Koji, Yamamoto Naoki, Yoshii Kentaro, Takashima Ikuo, Kobayashi Takeshi, Miura Tomoyuki, Igarashi Tatsuhiko, Hishiki Takayuki Kato Fumihiro, Ishida Yuki, Oishi Shinya, Fujii Nobutaka, Watanabe Satoru, Vasudevan Subhash G, Tajima Shigeru, Takasaki Tomohiko, Suzuki Youichi, Ichiyama Koji, Yamamoto Naoki, Yoshii Kentaro, Takashima Ikuo, Kobayashi Takeshi, Miura Tomoyuki, Igarashi Tatsuhiko, Hishiki Takayuki Kato Fumihiro, Ishida Yuki, Oishi Shinya, Fujii Nobutaka, Watanabe Satoru, Vasudevan Subhash G, Tajima Shigeru, Takasaki Tomohiko, Suzuki Youichi, Ichiyama Koji, Yamamoto Naoki, Yoshii Kentaro, Takashima Ikuo, Kobayashi Takeshi, Miura Tomoyuki, Igarashi Tatsuhiko, Hishiki Takayuki Novel antiviral activity of bromocriptine against dengue virus replication Novel antiviral activity of bromocriptine against dengue virus replication Novel antiviral activity of bromocriptine against dengue virus replication Antiviral Research, 131, 141-147 Antiviral Research, 131, 141-147 Antiviral Research, 131, 141-147 2016 Refereed Disclose to all
Noguchi Taro, Oishi Shinya, Honda Kaori, Kondoh Yasumitsu, Saito Tamio, Ohno Hiroaki, Osada Hiroyuki, Fujii Nobutaka Noguchi Taro, Oishi Shinya, Honda Kaori, Kondoh Yasumitsu, Saito Tamio, Ohno Hiroaki, Osada Hiroyuki, Fujii Nobutaka Noguchi Taro, Oishi Shinya, Honda Kaori, Kondoh Yasumitsu, Saito Tamio, Ohno Hiroaki, Osada Hiroyuki, Fujii Nobutaka Screening of a virtual mirror-image library of natural products Screening of a virtual mirror-image library of natural products Screening of a virtual mirror-image library of natural products Chemical Communications, 52, 49, 7656 Chemical Communications, 52, 49, 7656 Chemical Communications, 52, 49, 7656 2016 Refereed Disclose to all
Ohno Hiroaki, Minamiguchi Daiki, Nakamura Shinya, Shu Keito, Okazaki Shiho, Honda Maho, Misu Ryosuke, Moriwaki Hirotomo, Nakanishi Shinsuke, Oishi Shinya, Kinoshita Takayoshi, Nakanishi Isao, Fujii Nobutaka Ohno Hiroaki, Minamiguchi Daiki, Nakamura Shinya, Shu Keito, Okazaki Shiho, Honda Maho, Misu Ryosuke, Moriwaki Hirotomo, Nakanishi Shinsuke, Oishi Shinya, Kinoshita Takayoshi, Nakanishi Isao, Fujii Nobutaka Ohno Hiroaki, Minamiguchi Daiki, Nakamura Shinya, Shu Keito, Okazaki Shiho, Honda Maho, Misu Ryosuke, Moriwaki Hirotomo, Nakanishi Shinsuke, Oishi Shinya, Kinoshita Takayoshi, Nakanishi Isao, Fujii Nobutaka Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors Bioorganic & Medicinal Chemistry, 24, 5, 1141 Bioorganic & Medicinal Chemistry, 24, 5, 1141 Bioorganic & Medicinal Chemistry, 24, 5, 1141 2016 Refereed Disclose to all
Naoe Saori, Yoshida Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Naoe Saori, Yoshida Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Naoe Saori, Yoshida Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne Journal of Organic Chemistry, 81, 13, 5698 Journal of Organic Chemistry, 81, 13, 5698 Journal of Organic Chemistry, 81, 13, 5698 2016 Refereed Disclose to all
Takenaga M, Yamamoto Y, Takeuchi T, Ohta Y, Tokura Y, Hamaguchi A, Asai D, Nakashima H, Oishi S, Fujii N Takenaga M, Yamamoto Y, Takeuchi T, Ohta Y, Tokura Y, Hamaguchi A, Asai D, Nakashima H, Oishi S, Fujii N Takenaga M, Yamamoto Y, Takeuchi T, Ohta Y, Tokura Y, Hamaguchi A, Asai D, Nakashima H, Oishi S, Fujii N Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor. Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor. Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor. Biochemical and biophysical research communications, 463, 3, 222-228 Biochemical and biophysical research communications, 463, 3, 222-228 Biochemical and biophysical research communications, 463, 3, 222-228 2015/07 Refereed Disclose to all
Oishi S, Kuroyanagi T, Kubo T, Montpas N, Yoshikawa Y, Misu R, Kobayashi Y, Ohno H, Heveker N, Furuya T, Fujii N Oishi S, Kuroyanagi T, Kubo T, Montpas N, Yoshikawa Y, Misu R, Kobayashi Y, Ohno H, Heveker N, Furuya T, Fujii N Oishi S, Kuroyanagi T, Kubo T, Montpas N, Yoshikawa Y, Misu R, Kobayashi Y, Ohno H, Heveker N, Furuya T, Fujii N Development of Novel CXC Chemokine Receptor 7 (CXCR7) Ligands: Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold. Development of Novel CXC Chemokine Receptor 7 (CXCR7) Ligands: Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold. Development of Novel CXC Chemokine Receptor 7 (CXCR7) Ligands: Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold. Journal of medicinal chemistry, 58, 13, 5218-5225 Journal of medicinal chemistry, 58, 13, 5218-5225 Journal of medicinal chemistry, 58, 13, 5218-5225 2015/06 Refereed Disclose to all
Tokimizu Y, Oishi S, Fujii N, Ohno H Tokimizu Y, Oishi S, Fujii N, Ohno H Tokimizu Y, Oishi S, Fujii N, Ohno H Gold-Catalyzed Cascade Cyclization of 2-Alkynyl-N-Propargylanilines by Rearrangement of a Propargyl Group. Gold-Catalyzed Cascade Cyclization of 2-Alkynyl-N-Propargylanilines by Rearrangement of a Propargyl Group. Gold-Catalyzed Cascade Cyclization of 2-Alkynyl-N-Propargylanilines by Rearrangement of a Propargyl Group. Angewandte Chemie (International ed. in English), 54, 27, 7862-7866 Angewandte Chemie (International ed. in English), 54, 27, 7862-7866 Angewandte Chemie (International ed. in English), 54, 27, 7862-7866 2015/06 Refereed Disclose to all
Kawabata H, Uchiyama T, Sakamoto S, Kanda J, Oishi S, Fujii N, Tomosugi N, Kadowaki N, Takaori-Kondo A Kawabata H, Uchiyama T, Sakamoto S, Kanda J, Oishi S, Fujii N, Tomosugi N, Kadowaki N, Takaori-Kondo A Kawabata H, Uchiyama T, Sakamoto S, Kanda J, Oishi S, Fujii N, Tomosugi N, Kadowaki N, Takaori-Kondo A A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression. Experimental hematology, 43, 5, 404-413 Experimental hematology, 43, 5, 404-413 Experimental hematology, 43, 5, 404-413 2015/05 Refereed Disclose to all
Zenda M, Yasui H, Oishi S, Masuda R, Fujii N, Koide T Zenda M, Yasui H, Oishi S, Masuda R, Fujii N, Koide T Zenda M, Yasui H, Oishi S, Masuda R, Fujii N, Koide T A cisplatin derivative that inhibits collagen fibril-formation in vitro. A cisplatin derivative that inhibits collagen fibril-formation in vitro. A cisplatin derivative that inhibits collagen fibril-formation in vitro. Chemical biology & drug design, 85, 5, 519-526 Chemical biology & drug design, 85, 5, 519-526 Chemical biology & drug design, 85, 5, 519-526 2015/05 Refereed Disclose to all
Okazaki S, Oishi S, Mizuhara T, Shimura K, Murayama H, Ohno H, Matsuoka M, Fujii N Okazaki S, Oishi S, Mizuhara T, Shimura K, Murayama H, Ohno H, Matsuoka M, Fujii N Okazaki S, Oishi S, Mizuhara T, Shimura K, Murayama H, Ohno H, Matsuoka M, Fujii N Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds. Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds. Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds. Organic & biomolecular chemistry, 13, 16, 4706-4713 Organic & biomolecular chemistry, 13, 16, 4706-4713 Organic & biomolecular chemistry, 13, 16, 4706-4713 2015/04 Refereed Disclose to all
Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors. Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors. Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors. Bioorganic & medicinal chemistry, 23, 8, 1776-1787 Bioorganic & medicinal chemistry, 23, 8, 1776-1787 Bioorganic & medicinal chemistry, 23, 8, 1776-1787 2015/04 Refereed Disclose to all
Naoe S, Saito T, Uchiyama M, Oishi S, Fujii N, Ohno H Naoe S, Saito T, Uchiyama M, Oishi S, Fujii N, Ohno H Naoe S, Saito T, Uchiyama M, Oishi S, Fujii N, Ohno H Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes. Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes. Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes. Organic letters, 17, 7, 1774-1777 Organic letters, 17, 7, 1774-1777 Organic letters, 17, 7, 1774-1777 2015/04 Refereed Disclose to all
Okazaki S, Mizuhara T, Shimura K, Murayama H, Ohno H, Oishi S, Matsuoka M, Fujii N Okazaki S, Mizuhara T, Shimura K, Murayama H, Ohno H, Oishi S, Matsuoka M, Fujii N Okazaki S, Mizuhara T, Shimura K, Murayama H, Ohno H, Oishi S, Matsuoka M, Fujii N Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold. Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold. Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold. Bioorganic & medicinal chemistry, 23, 7, 1447-1452 Bioorganic & medicinal chemistry, 23, 7, 1447-1452 Bioorganic & medicinal chemistry, 23, 7, 1447-1452 2015/04 Refereed Disclose to all
Montpas N, Cabana J, St-Onge G, Gravel S, Morin G, Kuroyanagi T, Lavigne P, Fujii N, Oishi S, Heveker N Montpas N, Cabana J, St-Onge G, Gravel S, Morin G, Kuroyanagi T, Lavigne P, Fujii N, Oishi S, Heveker N Montpas N, Cabana J, St-Onge G, Gravel S, Morin G, Kuroyanagi T, Lavigne P, Fujii N, Oishi S, Heveker N Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants. Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants. Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants. Biochemistry, 54, 7, 1505-1515 Biochemistry, 54, 7, 1505-1515 Biochemistry, 54, 7, 1505-1515 2015/02 Refereed Disclose to all
Tokimizu Y, Wieteck M, Rudolph M, Oishi S, Fujii N, Hashmi AS, Ohno H Tokimizu Y, Wieteck M, Rudolph M, Oishi S, Fujii N, Hashmi AS, Ohno H Tokimizu Y, Wieteck M, Rudolph M, Oishi S, Fujii N, Hashmi AS, Ohno H Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides. Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides. Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides. Organic letters, 17, 3, 604-607 Organic letters, 17, 3, 604-607 Organic letters, 17, 3, 604-607 2015/02 Refereed Disclose to all
Tsunematsu Y, Nishimura S, Hattori A, Oishi S, Fujii N, Kakeya H Tsunematsu Y, Nishimura S, Hattori A, Oishi S, Fujii N, Kakeya H Tsunematsu Y, Nishimura S, Hattori A, Oishi S, Fujii N, Kakeya H Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-β signaling modulators from Streptomyces sp. Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-β signaling modulators from Streptomyces sp. Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-β signaling modulators from Streptomyces sp. Organic letters, 17, 2, 258-261 Organic letters, 17, 2, 258-261 Organic letters, 17, 2, 258-261 2015/01 Refereed Disclose to all
Nabika R, Suyama TL, Hau AM, Misu R, Ohno H, Ishmael JE, McPhail KL, Oishi S, Fujii N Nabika R, Suyama TL, Hau AM, Misu R, Ohno H, Ishmael JE, McPhail KL, Oishi S, Fujii N Nabika R, Suyama TL, Hau AM, Misu R, Ohno H, Ishmael JE, McPhail KL, Oishi S, Fujii N Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A. Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A. Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A. Bioorganic & medicinal chemistry letters, 25, 2, 302-306 Bioorganic & medicinal chemistry letters, 25, 2, 302-306 Bioorganic & medicinal chemistry letters, 25, 2, 302-306 2015/01 Refereed Disclose to all
Matsuda Y, Naoe S, Oishi S, Fujii N, Ohno H Matsuda Y, Naoe S, Oishi S, Fujii N, Ohno H Matsuda Y, Naoe S, Oishi S, Fujii N, Ohno H Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation. Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation. Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation. Chemistry (Weinheim an der Bergstrasse, Germany), 21, 4, 1463-1467 Chemistry (Weinheim an der Bergstrasse, Germany), 21, 4, 1463-1467 Chemistry (Weinheim an der Bergstrasse, Germany), 21, 4, 1463-1467 2015/01 Refereed Disclose to all
Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, Fujii Nobutaka, Kaku Mitsuo, Kodama Eiichi N. Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, Fujii Nobutaka, Kaku Mitsuo, Kodama Eiichi N. Miyamoto Fusako, Kawaji Kumi, Oishi Shinya, Fujii Nobutaka, Kaku Mitsuo, Kodama Eiichi N. Anti-HIV-1 activity determined by beta-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method Anti-HIV-1 activity determined by beta-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method Anti-HIV-1 activity determined by beta-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method Antiviral Chemistry & Chemotherapy, 24, 2, 77-82 Antiviral Chemistry & Chemotherapy, 24, 2, 77-82 Antiviral Chemistry & Chemotherapy, 24, 2, 77-82 2015 Refereed Disclose to all
Iwata Akira, Inuki Shinsuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Iwata Akira, Inuki Shinsuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Iwata Akira, Inuki Shinsuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides Tetrahedron, 71, 37, 6585 Tetrahedron, 71, 37, 6585 Tetrahedron, 71, 37, 6585 2015 Refereed Disclose to all
Umatani Chie, Misu Ryosuke, Oishi Shinya, Yamaguchi Kazuhiko, Abe Hideki, Oka Yoshitaka Umatani Chie, Misu Ryosuke, Oishi Shinya, Yamaguchi Kazuhiko, Abe Hideki, Oka Yoshitaka Umatani Chie, Misu Ryosuke, Oishi Shinya, Yamaguchi Kazuhiko, Abe Hideki, Oka Yoshitaka GnRH suppresses excitability of visual processing neurons in the optic tectum GnRH suppresses excitability of visual processing neurons in the optic tectum GnRH suppresses excitability of visual processing neurons in the optic tectum Journal of Neurophysiology, 114, 5, 2775-2784 Journal of Neurophysiology, 114, 5, 2775-2784 Journal of Neurophysiology, 114, 5, 2775-2784 2015 Refereed Disclose to all
Shimura Kazuya, Miyazato Paola, Oishi Shinya, Fujii Nobutaka, Matsuoka Masao Shimura Kazuya, Miyazato Paola, Oishi Shinya, Fujii Nobutaka, Matsuoka Masao Shimura Kazuya, Miyazato Paola, Oishi Shinya, Fujii Nobutaka, Matsuoka Masao Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread Virology, 484, 364-376 Virology, 484, 364-376 Virology, 484, 364-376 2015 Refereed Disclose to all
Misu Ryosuke, Yamamoto Koki, Yamada Ai, Noguchi Taro, Ohno Hiroaki, Yamamura Takashi, Okamura Hiroaki, Matsuda Fuko, Ohkura Satoshi, Oishi Shinya, Fujii Nobutaka Misu Ryosuke, Yamamoto Koki, Yamada Ai, Noguchi Taro, Ohno Hiroaki, Yamamura Takashi, Okamura Hiroaki, Matsuda Fuko, Ohkura Satoshi, Oishi Shinya, Fujii Nobutaka Misu Ryosuke, Yamamoto Koki, Yamada Ai, Noguchi Taro, Ohno Hiroaki, Yamamura Takashi, Okamura Hiroaki, Matsuda Fuko, Ohkura Satoshi, Oishi Shinya, Fujii Nobutaka Structure-activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists Structure-activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists Structure-activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists Medchemcomm, 6, 3, 476 Medchemcomm, 6, 3, 476 Medchemcomm, 6, 3, 476 2015 Refereed Disclose to all
Taguchi Masamitsu, Tokimizu Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Taguchi Masamitsu, Tokimizu Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Taguchi Masamitsu, Tokimizu Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group Organic Letters, 17, 24, 6250-6253 Organic Letters, 17, 24, 6250-6253 Organic Letters, 17, 24, 6250-6253 2015 Refereed Disclose to all
Nabika R, Oishi S, Misu R, Ohno H, Fujii N Nabika R, Oishi S, Misu R, Ohno H, Fujii N Nabika R, Oishi S, Misu R, Ohno H, Fujii N Synthesis of IB-01212 by multiple N-methylations of peptide bonds. Synthesis of IB-01212 by multiple N-methylations of peptide bonds. Synthesis of IB-01212 by multiple N-methylations of peptide bonds. Bioorganic & medicinal chemistry, 22, 21, 6156-6162 Bioorganic & medicinal chemistry, 22, 21, 6156-6162 Bioorganic & medicinal chemistry, 22, 21, 6156-6162 2014/11 Refereed Disclose to all
Misu R, Oishi S, Yamada A, Yamamura T, Matsuda F, Yamamoto K, Noguchi T, Ohno H, Okamura H, Ohkura S, Fujii N Misu R, Oishi S, Yamada A, Yamamura T, Matsuda F, Yamamoto K, Noguchi T, Ohno H, Okamura H, Ohkura S, Fujii N Misu R, Oishi S, Yamada A, Yamamura T, Matsuda F, Yamamoto K, Noguchi T, Ohno H, Okamura H, Ohkura S, Fujii N Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. Journal of medicinal chemistry, 57, 20, 8646-8651 Journal of medicinal chemistry, 57, 20, 8646-8651 Journal of medicinal chemistry, 57, 20, 8646-8651 2014/10 Refereed Disclose to all
Tsutsui A, Imamaki R, Kitazume S, Hanashima S, Yamaguchi Y, Kaneda M, Oishi S, Fujii N, Kurbangalieva A, Taniguchi N, Tanaka K Tsutsui A, Imamaki R, Kitazume S, Hanashima S, Yamaguchi Y, Kaneda M, Oishi S, Fujii N, Kurbangalieva A, Taniguchi N, Tanaka K Tsutsui A, Imamaki R, Kitazume S, Hanashima S, Yamaguchi Y, Kaneda M, Oishi S, Fujii N, Kurbangalieva A, Taniguchi N, Tanaka K Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress. Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress. Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress. Organic & biomolecular chemistry, 12, 28, 5151-5157 Organic & biomolecular chemistry, 12, 28, 5151-5157 Organic & biomolecular chemistry, 12, 28, 5151-5157 2014/07 Refereed Disclose to all
Kaneda M, Misu R, Ohno H, Hirasawa A, Ieda N, Uenoyama Y, Tsukamura H, Maeda K, Oishi S, Fujii N Kaneda M, Misu R, Ohno H, Hirasawa A, Ieda N, Uenoyama Y, Tsukamura H, Maeda K, Oishi S, Fujii N Kaneda M, Misu R, Ohno H, Hirasawa A, Ieda N, Uenoyama Y, Tsukamura H, Maeda K, Oishi S, Fujii N Design and synthesis of fluorescent probes for GPR54. Design and synthesis of fluorescent probes for GPR54. Design and synthesis of fluorescent probes for GPR54. Bioorganic & medicinal chemistry, 22, 13, 3325-3330 Bioorganic & medicinal chemistry, 22, 13, 3325-3330 Bioorganic & medicinal chemistry, 22, 13, 3325-3330 2014/07 Refereed Disclose to all
Tokimizu Y, Oishi S, Fujii N, Ohno H Tokimizu Y, Oishi S, Fujii N, Ohno H Tokimizu Y, Oishi S, Fujii N, Ohno H Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines. Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines. Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines. Organic Letters, 16, 11, 3138-3141 Organic Letters, 16, 11, 3138-3141 Organic Letters, 16, 11, 3138-3141 2014/06 Refereed English Research paper(scientific journal) Disclose to all
Takeuchi T, Oishi S, Kaneda M, Misu R, Ohno H, Sawada J, Asai A, Nakamura S, Nakanishi I, Fujii N Takeuchi T, Oishi S, Kaneda M, Misu R, Ohno H, Sawada J, Asai A, Nakamura S, Nakanishi I, Fujii N Takeuchi T, Oishi S, Kaneda M, Misu R, Ohno H, Sawada J, Asai A, Nakamura S, Nakanishi I, Fujii N Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors. Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors. Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors. Bioorganic & medicinal chemistry, 22, 12, 3171-3179 Bioorganic & medicinal chemistry, 22, 12, 3171-3179 Bioorganic & medicinal chemistry, 22, 12, 3171-3179 2014/06 Refereed Disclose to all
Takeuchi T, Oishi S, Kaneda M, Ohno H, Nakamura S, Nakanishi I, Yamane M, Sawada J, Asai A, Fujii N Takeuchi T, Oishi S, Kaneda M, Ohno H, Nakamura S, Nakanishi I, Yamane M, Sawada J, Asai A, Fujii N Takeuchi T, Oishi S, Kaneda M, Ohno H, Nakamura S, Nakanishi I, Yamane M, Sawada J, Asai A, Fujii N Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility. Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility. Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility. ACS Medicinal Chemistry Letters, 5, 5, 566-571 ACS Medicinal Chemistry Letters, 5, 5, 566-571 ACS Medicinal Chemistry Letters, 5, 5, 566-571 2014/05 Refereed English Research paper(scientific journal) Disclose to all
K. Sano; R. Masuda; H. Hisada; S. Oishi; K. Shimokawa; M. Ono; N. Fujii; H. Saji; T. Mukai Sano K, Masuda R, Hisada H, Oishi S, Shimokawa K, Ono M, Fujii N, Saji H, Mukai T K. Sano; R. Masuda; H. Hisada; S. Oishi; K. Shimokawa; M. Ono; N. Fujii; H. Saji; T. Mukai A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging. A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging Bioorganic and Medicinal Chemistry Letters, 24, 5, 1386-1388 Bioorganic & medicinal chemistry letters, 24, 5, 1386-1388 Bioorganic and Medicinal Chemistry Letters, 24, 5, 1386-1388 2014/03 Refereed English Disclose to all
A. Iwata; S. Inuki; S. Oishi; N. Fujii; H. Ohno Iwata A, Inuki S, Oishi S, Fujii N, Ohno H A. Iwata; S. Inuki; S. Oishi; N. Fujii; H. Ohno Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation. Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation Chemical Communications, 50, 3, 298-300 Chemical communications (Cambridge, England), 50, 3, 298-300 Chemical Communications, 50, 3, 298-300 2014/01 Refereed English Disclose to all
Naoe Saori, Suzuki Yamato, Hirano Kimio, Inaba Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Naoe Saori, Suzuki Yamato, Hirano Kimio, Inaba Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Naoe Saori, Suzuki Yamato, Hirano Kimio, Inaba Yusuke, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Gold(I)-Catalyzed Regioselective Inter-/Intramolecular Addition Cascade of Di- and Triynes for Direct Construction of Substituted Naphthalenes (vol 77, pg 4907, 2012) Gold(I)-Catalyzed Regioselective Inter-/Intramolecular Addition Cascade of Di- and Triynes for Direct Construction of Substituted Naphthalenes (vol 77, pg 4907, 2012) Gold(I)-Catalyzed Regioselective Inter-/Intramolecular Addition Cascade of Di- and Triynes for Direct Construction of Substituted Naphthalenes (vol 77, pg 4907, 2012) Journal of Organic Chemistry, 79, 5, 2339 Journal of Organic Chemistry, 79, 5, 2339 Journal of Organic Chemistry, 79, 5, 2339 2014 Refereed Disclose to all
Ohno Hiroaki, Oishi Shinya, Fujii Nobutaka Ohno Hiroaki, Oishi Shinya, Fujii Nobutaka Ohno Hiroaki, Oishi Shinya, Fujii Nobutaka Gold-Catalyzed Atom-Economical Cascade Reactions of Alkynes for Ring Formation Gold-Catalyzed Atom-Economical Cascade Reactions of Alkynes for Ring Formation Gold-Catalyzed Atom-Economical Cascade Reactions of Alkynes for Ring Formation Journal of Synthetic Organic Chemistry Japan, 72, 11, 1218-1227 Journal of Synthetic Organic Chemistry Japan, 72, 11, 1218-1227 Journal of Synthetic Organic Chemistry Japan, 72, 11, 1218-1227 2014 Refereed Disclose to all
H. Ohno; H. Chiba; S. Inuki; S. Oishi; N. Fujii Ohno Hiroaki, Chiba Hiroaki, Inuki Shinsuke, Oishi Shinya, Fujii Nobutaka H. Ohno; H. Chiba; S. Inuki; S. Oishi; N. Fujii The synthesis of alkaloids using transition-metal-catalyzed intramolecular amination reactions The Synthesis of Alkaloids Using Transition-Metal-Catalyzed Intramolecular Amination Reactions The synthesis of alkaloids using transition-metal-catalyzed intramolecular amination reactions Synlett, 25, 2, 179-192 Synlett, 25, 2, 179-192 Synlett, 25, 2, 179-192 2014 Refereed English Disclose to all
Y. Naniwa; K. Nakatsukasa; S. Setsuda; S. Oishi; N. Fujii; F. Matsuda; Y. Uenoyama; H. Tsukamura; K.-I. Maeda; S. Ohkura Naniwa Y, Nakatsukasa K, Setsuda S, Oishi S, Fujii N, Matsuda F, Uenoyama Y, Tsukamura H, Maeda K, Ohkura S Y. Naniwa; K. Nakatsukasa; S. Setsuda; S. Oishi; N. Fujii; F. Matsuda; Y. Uenoyama; H. Tsukamura; K.-I. Maeda; S. Ohkura Effects of full-length kisspeptin administration on follicular development in Japanese black beef cows Effects of full-length kisspeptin administration on follicular development in Japanese Black beef cows. Effects of full-length kisspeptin administration on follicular development in Japanese black beef cows Journal of Reproduction and Development, 59, 6, 588-594 The Journal of reproduction and development, 59, 6, 588-594 Journal of Reproduction and Development, 59, 6, 588-594 2013/12 Refereed English Disclose to all
T. Nakahara; Y. Uenoyama; A. Iwase; S. Oishi; S. Nakamura; S. Minabe; Y. Watanabe; C. Deura; T. Noguchi; N. Fujii; F. Kikkawa; K.-I. Maeda; H. Tsukamura Nakahara T, Uenoyama Y, Iwase A, Oishi S, Nakamura S, Minabe S, Watanabe Y, Deura C, Noguchi T, Fujii N, Kikkawa F, Maeda K, Tsukamura H T. Nakahara; Y. Uenoyama; A. Iwase; S. Oishi; S. Nakamura; S. Minabe; Y. Watanabe; C. Deura; T. Noguchi; N. Fujii; F. Kikkawa; K.-I. Maeda; H. Tsukamura Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats. Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats Journal of Reproduction and Development, 59, 5, 479-484 The Journal of reproduction and development, 59, 5, 479-484 Journal of Reproduction and Development, 59, 5, 479-484 2013/10 Refereed English Disclose to all
T. Mizuhara; T. Kato; A. Hirai; H. Kurihara; Y. Shimada; M. Taniguchi; H. Maeta; H. Togami; K. Shimura; M. Matsuoka; S. Okazaki; T. Takeuchi; H. Ohno; S. Oishi; N. Fujii Mizuhara T, Kato T, Hirai A, Kurihara H, Shimada Y, Taniguchi M, Maeta H, Togami H, Shimura K, Matsuoka M, Okazaki S, Takeuchi T, Ohno H, Oishi S, Fujii N T. Mizuhara; T. Kato; A. Hirai; H. Kurihara; Y. Shimada; M. Taniguchi; H. Maeta; H. Togami; K. Shimura; M. Matsuoka; S. Okazaki; T. Takeuchi; H. Ohno; S. Oishi; N. Fujii Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents. Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents Bioorganic and Medicinal Chemistry Letters, 23, 16, 4557-4561 Bioorganic & medicinal chemistry letters, 23, 16, 4557-4561 Bioorganic and Medicinal Chemistry Letters, 23, 16, 4557-4561 2013/08 Refereed English Disclose to all
K. Shimane; K. Kawaji; F. Miyamoto; S. Oishi; K. Watanabe; Y. Sakagami; N. Fujii; K. Shimura; M. Matsuoka; M. Kaku; S.G. Sarafianos; E.N. Kodama Shimane K, Kawaji K, Miyamoto F, Oishi S, Watanabe K, Sakagami Y, Fujii N, Shimura K, Matsuoka M, Kaku M, Sarafianos SG, Kodama EN K. Shimane; K. Kawaji; F. Miyamoto; S. Oishi; K. Watanabe; Y. Sakagami; N. Fujii; K. Shimura; M. Matsuoka; M. Kaku; S.G. Sarafianos; E.N. Kodama HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against t-20-resistant strains HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against T-20-resistant strains. HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against t-20-resistant strains Antimicrobial Agents and Chemotherapy, 57, 8, 4035-4038 Antimicrobial agents and chemotherapy, 57, 8, 4035-4038 Antimicrobial Agents and Chemotherapy, 57, 8, 4035-4038 2013/08 Refereed English Disclose to all
T. Noguchi; S. Oishi; K. Honda; Y. Kondoh; T. Saito; T. Kubo; M. Kaneda; H. Ohno; H. Osada; N. Fujii Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Kubo T, Kaneda M, Ohno H, Osada H, Fujii N T. Noguchi; S. Oishi; K. Honda; Y. Kondoh; T. Saito; T. Kubo; M. Kaneda; H. Ohno; H. Osada; N. Fujii Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: Identification of novel peptidic inhibitors Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: Identification of novel peptidic inhibitors Bioorganic and Medicinal Chemistry Letters, 23, 13, 3802-3805 Bioorganic & medicinal chemistry letters, 23, 13, 3802-3805 Bioorganic and Medicinal Chemistry Letters, 23, 13, 3802-3805 2013/07 Refereed English Disclose to all
Y. Kobayashi; S. Oishi; K. Kobayashi; H. Ohno; H. Tsutsumi; Y. Hata; N. Fujii Kobayashi Y, Oishi S, Kobayashi K, Ohno H, Tsutsumi H, Hata Y, Fujii N Y. Kobayashi; S. Oishi; K. Kobayashi; H. Ohno; H. Tsutsumi; Y. Hata; N. Fujii Synthesis and functional analysis of deferriferrichrysin derivatives: Application to colorimetric pH indicators Synthesis and functional analysis of deferriferrichrysin derivatives: application to colorimetric pH indicators. Synthesis and functional analysis of deferriferrichrysin derivatives: Application to colorimetric pH indicators Bioorganic and Medicinal Chemistry, 21, 14, 4296-4300 Bioorganic & medicinal chemistry, 21, 14, 4296-4300 Bioorganic and Medicinal Chemistry, 21, 14, 4296-4300 2013/07 Refereed English Disclose to all
H. Chiba; Y. Sakai; A. Ohara; S. Oishi; N. Fujii; H. Ohno Chiba H, Sakai Y, Ohara A, Oishi S, Fujii N, Ohno H H. Chiba; Y. Sakai; A. Ohara; S. Oishi; N. Fujii; H. Ohno Convergent synthesis of (-)-quinocarcin based on the combination of sonogashira coupling and gold(I)-catalyzed 6-endo-dig hydroamination Convergent synthesis of (-)-quinocarcin based on the combination of Sonogashira coupling and gold(I)-catalyzed 6-endo-dig hydroamination. Convergent synthesis of (-)-quinocarcin based on the combination of sonogashira coupling and gold(I)-catalyzed 6-endo-dig hydroamination Chemistry - A European Journal, 19, 27, 8875-8883 Chemistry (Weinheim an der Bergstrasse, Germany), 19, 27, 8875-8883 Chemistry - A European Journal, 19, 27, 8875-8883 2013/07 Refereed English Disclose to all
Y. Yoshimitsu; S. Inuki; S. Oishi; N. Fujii; H. Ohno Yoshimitsu Y, Inuki S, Oishi S, Fujii N, Ohno H Y. Yoshimitsu; S. Inuki; S. Oishi; N. Fujii; H. Ohno Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: Synthetic study of laurendecumallene B Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: synthetic study of laurendecumallene B. Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: Synthetic study of laurendecumallene B Organic Letters, 15, 12, 3046-3049 Organic letters, 15, 12, 3046-3049 Organic Letters, 15, 12, 3046-3049 2013/06 Refereed English Disclose to all
Y. Yoshikawa; S. Oishi; T. Kubo; N. Tanahara; N. Fujii; T. Furuya Yoshikawa Y, Oishi S, Kubo T, Tanahara N, Fujii N, Furuya T Y. Yoshikawa; S. Oishi; T. Kubo; N. Tanahara; N. Fujii; T. Furuya Optimized method of G-protein-coupled receptor homology modeling: Its application to the discovery of novel CXCR7 ligands Optimized method of G-protein-coupled receptor homology modeling: its application to the discovery of novel CXCR7 ligands. Optimized method of G-protein-coupled receptor homology modeling: Its application to the discovery of novel CXCR7 ligands Journal of Medicinal Chemistry, 56, 11, 4236-4251 Journal of medicinal chemistry, 56, 11, 4236-4251 Journal of Medicinal Chemistry, 56, 11, 4236-4251 2013/06 Refereed English Disclose to all
Z. Hou; S. Oishi; Y. Suzuki; T. Kure; I. Nakanishi; A. Hirasawa; G. Tsujimoto; H. Ohno; N. Fujii Hou Z, Oishi S, Suzuki Y, Kure T, Nakanishi I, Hirasawa A, Tsujimoto G, Ohno H, Fujii N Z. Hou; S. Oishi; Y. Suzuki; T. Kure; I. Nakanishi; A. Hirasawa; G. Tsujimoto; H. Ohno; N. Fujii Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: Application to the development of a new class of CK2 inhibitors Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors. Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: Application to the development of a new class of CK2 inhibitors Organic and Biomolecular Chemistry, 11, 20, 3288-3296 Organic & biomolecular chemistry, 11, 20, 3288-3296 Organic and Biomolecular Chemistry, 11, 20, 3288-3296 2013/05 Refereed English Disclose to all
R. Misu; S. Oishi; S. Setsuda; T. Noguchi; M. Kaneda; H. Ohno; B. Evans; J.-M. Navenot; S.C. Peiper; N. Fujii Misu R, Oishi S, Setsuda S, Noguchi T, Kaneda M, Ohno H, Evans B, Navenot JM, Peiper SC, Fujii N R. Misu; S. Oishi; S. Setsuda; T. Noguchi; M. Kaneda; H. Ohno; B. Evans; J.-M. Navenot; S.C. Peiper; N. Fujii Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes. Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes Bioorganic and Medicinal Chemistry Letters, 23, 9, 2628-2631 Bioorganic & medicinal chemistry letters, 23, 9, 2628-2631 Bioorganic and Medicinal Chemistry Letters, 23, 9, 2628-2631 2013/05 Refereed English Disclose to all
R. Misu; T. Noguchi; H. Ohno; S. Oishi; N. Fujii Misu R, Noguchi T, Ohno H, Oishi S, Fujii N R. Misu; T. Noguchi; H. Ohno; S. Oishi; N. Fujii Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists. Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists Bioorganic and Medicinal Chemistry, 21, 8, 2413-2417 Bioorganic & medicinal chemistry, 21, 8, 2413-2417 Bioorganic and Medicinal Chemistry, 21, 8, 2413-2417 2013/04 Refereed English Disclose to all
T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182 Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182. Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182 Bioorganic and Medicinal Chemistry, 21, 7, 2079-2087 Bioorganic & medicinal chemistry, 21, 7, 2079-2087 Bioorganic and Medicinal Chemistry, 21, 7, 2079-2087 2013/04 Refereed English Disclose to all
K. Izumi; K. Kawaji; F. Miyamoto; K. Shimane; K. Shimura; Y. Sakagami; T. Hattori; K. Watanabe; S. Oishi; N. Fujii; M. Matsuoka; M. Kaku; S.G. Sarafianos; E.N. Kodama Izumi K, Kawaji K, Miyamoto F, Shimane K, Shimura K, Sakagami Y, Hattori T, Watanabe K, Oishi S, Fujii N, Matsuoka M, Kaku M, Sarafianos SG, Kodama EN K. Izumi; K. Kawaji; F. Miyamoto; K. Shimane; K. Shimura; Y. Sakagami; T. Hattori; K. Watanabe; S. Oishi; N. Fujii; M. Matsuoka; M. Kaku; S.G. Sarafianos; E.N. Kodama Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design. Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design International Journal of Biochemistry and Cell Biology, 45, 4, 908-915 The international journal of biochemistry & cell biology, 45, 4, 908-915 International Journal of Biochemistry and Cell Biology, 45, 4, 908-915 2013/04 Refereed English Disclose to all
Nakahara Tatsuo, Uenoyama Yoshihisa, Iwase Akira, Oishi Shinya, Nakamura Sho, Minabe Shiori, Watanabe Youki, Deura Chikaya, Noguchi Taro, Fuji Nobutaka, Kikkawa Fumitaka, Maeda Kei-ichiro, Tsukamura Hiroko Nakahara Tatsuo, Uenoyama Yoshihisa, Iwase Akira, Oishi Shinya, Nakamura Sho, Minabe Shiori, Watanabe Youki, Deura Chikaya, Noguchi Taro, Fuji Nobutaka, Kikkawa Fumitaka, Maeda Kei-ichiro, Tsukamura Hiroko Nakahara Tatsuo, Uenoyama Yoshihisa, Iwase Akira, Oishi Shinya, Nakamura Sho, Minabe Shiori, Watanabe Youki, Deura Chikaya, Noguchi Taro, Fuji Nobutaka, Kikkawa Fumitaka, Maeda Kei-ichiro, Tsukamura Hiroko Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats Journal of Reproduction and Development, 59, 5, 479-484 Journal of Reproduction and Development, 59, 5, 479-484 Journal of Reproduction and Development, 59, 5, 479-484 2013 Refereed Disclose to all
Naniwa Yousuke, Nakatsukasa Keisuke, Setsuda Shohei, Oishi Shinya, Fuji Nobutaka, Matsuda Fuko, Uenoyama Yoshihisa, Tsukamura Hiroko, Maeda Kei-ichiro, Ohkura Satoshi Naniwa Yousuke, Nakatsukasa Keisuke, Setsuda Shohei, Oishi Shinya, Fuji Nobutaka, Matsuda Fuko, Uenoyama Yoshihisa, Tsukamura Hiroko, Maeda Kei-ichiro, Ohkura Satoshi Naniwa Yousuke, Nakatsukasa Keisuke, Setsuda Shohei, Oishi Shinya, Fuji Nobutaka, Matsuda Fuko, Uenoyama Yoshihisa, Tsukamura Hiroko, Maeda Kei-ichiro, Ohkura Satoshi Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows Journal of Reproduction and Development, 59, 6, 588-594 Journal of Reproduction and Development, 59, 6, 588-594 Journal of Reproduction and Development, 59, 6, 588-594 2013 Refereed Disclose to all
Takeuchi Tomoki, Oishi Shinya, Kaneda Masato, Ohno Hiroaki, Sawada Jun-ichi, Asai Akira, Fujii Nobutaka Takeuchi Tomoki, Oishi Shinya, Kaneda Masato, Ohno Hiroaki, Sawada Jun-ichi, Asai Akira, Fujii Nobutaka Takeuchi Tomoki, Oishi Shinya, Kaneda Masato, Ohno Hiroaki, Sawada Jun-ichi, Asai Akira, Fujii Nobutaka Kinesin spindle protein (KSP) inhibitors with carbazole and diaryl amine scaffolds Kinesin spindle protein (KSP) inhibitors with carbazole and diaryl amine scaffolds Kinesin spindle protein (KSP) inhibitors with carbazole and diaryl amine scaffolds Abstracts of Papers of the American Chemical Society, 246 Abstracts of Papers of the American Chemical Society, 246 Abstracts of Papers of the American Chemical Society, 246 2013 Refereed Disclose to all
Y. Yoshimitsu; J. Miyagaki; S. Oishi; N. Fujii; H. Ohno Yoshimitsu Yuji, Miyagaki Jun, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Y. Yoshimitsu; J. Miyagaki; S. Oishi; N. Fujii; H. Ohno Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis Tetrahedron, 69, 21, 4211-4220 Tetrahedron, 69, 21, 4211-4220 Tetrahedron, 69, 21, 4211-4220 2013 Refereed English Disclose to all
Iwata Akira, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Iwata Akira, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Iwata Akira, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Synthesis of the fused tetracyclic spiroindoles via palladium-catalyzed cascade reaction Synthesis of the fused tetracyclic spiroindoles via palladium-catalyzed cascade reaction Synthesis of the fused tetracyclic spiroindoles via palladium-catalyzed cascade reaction Abstracts of Papers of the American Chemical Society, 50, 3, 298-300 Abstracts of Papers of the American Chemical Society, 50, 3, 298-300 Abstracts of Papers of the American Chemical Society, 50, 3, 298-300 2013 Refereed Disclose to all
G. Tanaka; I. Nakase; Y. Fukuda; R. Masuda; S. Oishi; K. Shimura; Y. Kawaguchi; T. Takatani-Nakase; Ü. Langel; A. Gräslund; K. Okawa; M. Matsuoka; N. Fujii; Y. Hatanaka; S. Futaki Tanaka G, Nakase I, Fukuda Y, Masuda R, Oishi S, Shimura K, Kawaguchi Y, Takatani-Nakase T, Langel U, Gräslund A, Okawa K, Matsuoka M, Fujii N, Hatanaka Y, Futaki S G. Tanaka; I. Nakase; Y. Fukuda; R. Masuda; S. Oishi; K. Shimura; Y. Kawaguchi; T. Takatani-Nakase; Ü. Langel; A. Gräslund; K. Okawa; M. Matsuoka; N. Fujii; Y. Hatanaka; S. Futaki CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV. CXCR4 stimulates macropinocytosis: Implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV Chemistry and Biology, 19, 11, 1437-1446 Chemistry & biology, 19, 11, 1437-1446 Chemistry and Biology, 19, 11, 1437-1446 2012/11 Refereed English Disclose to all
T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin- 6-imine derivatives for potent anti-HIV agents Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents. Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin- 6-imine derivatives for potent anti-HIV agents Bioorganic and Medicinal Chemistry, 20, 21, 6434-6441 Bioorganic & medicinal chemistry, 20, 21, 6434-6441 Bioorganic and Medicinal Chemistry, 20, 21, 6434-6441 2012/11 Refereed English Disclose to all
Y. Otani; T. Kijima; S. Kohmo; S. Oishi; T. Minami; I. Nagatomo; R. Takahashi; H. Hirata; M. Suzuki; K. Inoue; Y. Takeda; H. Kida; I. Tachibana; N. Fujii; A. Kumanogoh Otani Y, Kijima T, Kohmo S, Oishi S, Minami T, Nagatomo I, Takahashi R, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Fujii N, Kumanogoh A Y. Otani; T. Kijima; S. Kohmo; S. Oishi; T. Minami; I. Nagatomo; R. Takahashi; H. Hirata; M. Suzuki; K. Inoue; Y. Takeda; H. Kida; I. Tachibana; N. Fujii; A. Kumanogoh Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016 Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016. Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016 FEBS Letters, 586, 20, 3639-3644 FEBS letters, 586, 20, 3639-3644 FEBS Letters, 586, 20, 3639-3644 2012/10 Refereed English Disclose to all
H. Chiba; S. Oishi; N. Fujii; H. Ohno Chiba H, Oishi S, Fujii N, Ohno H H. Chiba; S. Oishi; N. Fujii; H. Ohno Total synthesis of (-)-quinocarcin by gold(I)-catalyzed regioselective hydroamination Total synthesis of (-)-quinocarcin by gold(I)-catalyzed regioselective hydroamination. Total synthesis of (-)-quinocarcin by gold(I)-catalyzed regioselective hydroamination Angewandte Chemie - International Edition, 51, 36, 9169-9172 Angewandte Chemie (International ed. in English), 51, 36, 9169-9172 Angewandte Chemie - International Edition, 51, 36, 9169-9172 2012/09 Refereed English Disclose to all
T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Mizuhara T, Oishi S, Ohno H, Shimura K, Matsuoka M, Fujii N T. Mizuhara; S. Oishi; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3] benzothiazin-6-imines and related tricyclic heterocycles Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles. Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3] benzothiazin-6-imines and related tricyclic heterocycles Organic and Biomolecular Chemistry, 10, 33, 6792-6802 Organic & biomolecular chemistry, 10, 33, 6792-6802 Organic and Biomolecular Chemistry, 10, 33, 6792-6802 2012/09 Refereed English Disclose to all
S. Oishi; N. Fujii Oishi S, Fujii N S. Oishi; N. Fujii Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4) Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4). Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4) Organic and Biomolecular Chemistry, 10, 30, 5720-5731 Organic & biomolecular chemistry, 10, 30, 5720-5731 Organic and Biomolecular Chemistry, 10, 30, 5720-5731 2012/08 Refereed English Disclose to all
X. Li; H. Qian; F. Miyamoto; T. Naito; K. Kawaji; K. Kajiwara; T. Hattori; M. Matsuoka; K. Watanabe; S. Oishi; N. Fujii; E.N. Kodama Li X, Qian H, Miyamoto F, Naito T, Kawaji K, Kajiwara K, Hattori T, Matsuoka M, Watanabe K, Oishi S, Fujii N, Kodama EN X. Li; H. Qian; F. Miyamoto; T. Naito; K. Kawaji; K. Kajiwara; T. Hattori; M. Matsuoka; K. Watanabe; S. Oishi; N. Fujii; E.N. Kodama A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats. A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats Biochemical and Biophysical Research Communications, 424, 2, 257-261 Biochemical and biophysical research communications, 424, 2, 257-261 Biochemical and Biophysical Research Communications, 424, 2, 257-261 2012/07 Refereed English Disclose to all
Y. Suzuki; S. Oishi; Y. Takei; M. Yasue; R. Misu; S. Naoe; Z. Hou; T. Kure; I. Nakanishi; H. Ohno; A. Hirasawa; G. Tsujimoto; N. Fujii Suzuki Y, Oishi S, Takei Y, Yasue M, Misu R, Naoe S, Hou Z, Kure T, Nakanishi I, Ohno H, Hirasawa A, Tsujimoto G, Fujii N Y. Suzuki; S. Oishi; Y. Takei; M. Yasue; R. Misu; S. Naoe; Z. Hou; T. Kure; I. Nakanishi; H. Ohno; A. Hirasawa; G. Tsujimoto; N. Fujii Design and synthesis of a novel class of CK2 inhibitors: Application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles. Design and synthesis of a novel class of CK2 inhibitors: Application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles Organic and Biomolecular Chemistry, 10, 25, 4907-4915 Organic & biomolecular chemistry, 10, 25, 4907-4915 Organic and Biomolecular Chemistry, 10, 25, 4907-4915 2012/07 Refereed English Disclose to all
S. Naoe; Y. Suzuki; K. Hirano; Y. Inaba; S. Oishi; N. Fujii; H. Ohno Naoe S, Suzuki Y, Hirano K, Inaba Y, Oishi S, Fujii N, Ohno H S. Naoe; Y. Suzuki; K. Hirano; Y. Inaba; S. Oishi; N. Fujii; H. Ohno Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes. Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes Journal of Organic Chemistry, 77, 11, 4907-4916 The Journal of organic chemistry, 77, 11, 4907-4916 Journal of Organic Chemistry, 77, 11, 4907-4916 2012/06 Refereed English Disclose to all
R. Masuda; S. Oishi; N. Tanahara; H. Ohno; A. Hirasawa; G. Tsujimoto; Y. Yano; K. Matsuzaki; J.-M. Navenot; S.C. Peiper; N. Fujii Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Yano Y, Matsuzaki K, Navenot JM, Peiper SC, Fujii N R. Masuda; S. Oishi; N. Tanahara; H. Ohno; A. Hirasawa; G. Tsujimoto; Y. Yano; K. Matsuzaki; J.-M. Navenot; S.C. Peiper; N. Fujii Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists. Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists Bioconjugate Chemistry, 23, 6, 1259-1265 Bioconjugate chemistry, 23, 6, 1259-1265 Bioconjugate Chemistry, 23, 6, 1259-1265 2012/06 Refereed English Disclose to all
K. Murata; T. Kitaori; S. Oishi; N. Watanabe; H. Yoshitomi; S. Tanida; M. Ishikawa; T. Kasahara; H. Shibuya; N. Fujii; T. Nagasawa; T. Nakamura; H. Ito Murata K, Kitaori T, Oishi S, Watanabe N, Yoshitomi H, Tanida S, Ishikawa M, Kasahara T, Shibuya H, Fujii N, Nagasawa T, Nakamura T, Ito H K. Murata; T. Kitaori; S. Oishi; N. Watanabe; H. Yoshitomi; S. Tanida; M. Ishikawa; T. Kasahara; H. Shibuya; N. Fujii; T. Nagasawa; T. Nakamura; H. Ito Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy PLoS ONE, 7, 5 PloS one, 7, 5 PLoS ONE, 7, 5 2012/05/18 Refereed English Disclose to all
Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N Development and application of fluorescent SDF-1 derivatives. Development and application of fluorescent SDF-1 derivatives. Development and application of fluorescent SDF-1 derivatives. Future medicinal chemistry, 4, 7, 837-844 Future medicinal chemistry, 4, 7, 837-844 Future medicinal chemistry, 4, 7, 837-844 2012/05 Refereed Disclose to all
K. Kobayashi; S. Oishi; Y. Kobayashi; H. Ohno; H. Tsutsumi; Y. Hata; N. Fujii Kobayashi K, Oishi S, Kobayashi Y, Ohno H, Tsutsumi H, Hata Y, Fujii N K. Kobayashi; S. Oishi; Y. Kobayashi; H. Ohno; H. Tsutsumi; Y. Hata; N. Fujii Synthesis and application of an N <sup>δ</sup>-acetyl-N <sup>δ</sup>-hydroxyornithine analog: Identification of novel metal complexes of deferriferrichrysin Synthesis and application of an Nδ-acetyl-Nδ-hydroxyornithine analog: identification of novel metal complexes of deferriferrichrysin. Synthesis and application of an N <sup>δ</sup>-acetyl-N <sup>δ</sup>-hydroxyornithine analog: Identification of novel metal complexes of deferriferrichrysin Bioorganic and Medicinal Chemistry, 20, 8, 2651-2655 Bioorganic & medicinal chemistry, 20, 8, 2651-2655 Bioorganic and Medicinal Chemistry, 20, 8, 2651-2655 2012/04 Refereed English Disclose to all
J.-M. Navenot; B. Evans; S. Oishi; S. Setsuda; N. Fujii; S.C. Peiper Navenot JM, Evans B, Oishi S, Setsuda S, Fujii N, Peiper SC J.-M. Navenot; B. Evans; S. Oishi; S. Setsuda; N. Fujii; S.C. Peiper The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma. The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma Melanoma Research, 22, 2, 140-150 Melanoma research, 22, 2, 140-150 Melanoma Research, 22, 2, 140-150 2012/04 Refereed English Disclose to all
Y. Yoshikawa; K. Kobayashi; S. Oishi; N. Fujii; T. Furuya Yoshikawa Y, Kobayashi K, Oishi S, Fujii N, Furuya T Y. Yoshikawa; K. Kobayashi; S. Oishi; N. Fujii; T. Furuya Molecular modeling study of cyclic pentapeptide CXCR4 antagonists: New insight into CXCR4-FC131 interactions Molecular modeling study of cyclic pentapeptide CXCR4 antagonists: new insight into CXCR4-FC131 interactions. Molecular modeling study of cyclic pentapeptide CXCR4 antagonists: New insight into CXCR4-FC131 interactions Bioorganic and Medicinal Chemistry Letters, 22, 6, 2146-2150 Bioorganic & medicinal chemistry letters, 22, 6, 2146-2150 Bioorganic and Medicinal Chemistry Letters, 22, 6, 2146-2150 2012/03 Refereed English Disclose to all
K. Kobayashi; S. Oishi; R. Hayashi; K. Tomita; T. Kubo; N. Tanahara; H. Ohno; Y. Yoshikawa; T. Furuya; M. Hoshino; N. Fujii Kobayashi K, Oishi S, Hayashi R, Tomita K, Kubo T, Tanahara N, Ohno H, Yoshikawa Y, Furuya T, Hoshino M, Fujii N K. Kobayashi; S. Oishi; R. Hayashi; K. Tomita; T. Kubo; N. Tanahara; H. Ohno; Y. Yoshikawa; T. Furuya; M. Hoshino; N. Fujii Structure-activity relationship study of a CXC chemokine receptor type 4 antagonist, FC131, using a series of alkene dipeptide isosteres Structure-activity relationship study of a CXC chemokine receptor type 4 antagonist, FC131, using a series of alkene dipeptide isosteres. Structure-activity relationship study of a CXC chemokine receptor type 4 antagonist, FC131, using a series of alkene dipeptide isosteres Journal of Medicinal Chemistry, 55, 6, 2746-2757 Journal of medicinal chemistry, 55, 6, 2746-2757 Journal of Medicinal Chemistry, 55, 6, 2746-2757 2012/03 Refereed English Disclose to all
Z. Hou; I. Nakanishi; T. Kinoshita; Y. Takei; M. Yasue; R. Misu; Y. Suzuki; S. Nakamura; T. Kure; H. Ohno; K. Murata; K. Kitaura; A. Hirasawa; G. Tsujimoto; S. Oishi; N. Fujii Hou Z, Nakanishi I, Kinoshita T, Takei Y, Yasue M, Misu R, Suzuki Y, Nakamura S, Kure T, Ohno H, Murata K, Kitaura K, Hirasawa A, Tsujimoto G, Oishi S, Fujii N Z. Hou; I. Nakanishi; T. Kinoshita; Y. Takei; M. Yasue; R. Misu; Y. Suzuki; S. Nakamura; T. Kure; H. Ohno; K. Murata; K. Kitaura; A. Hirasawa; G. Tsujimoto; S. Oishi; N. Fujii Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds. Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds Journal of Medicinal Chemistry, 55, 6, 2899-2903 Journal of medicinal chemistry, 55, 6, 2899-2903 Journal of Medicinal Chemistry, 55, 6, 2899-2903 2012/03 Refereed English Disclose to all
Suzuki Y, Naoe S, Oishi S, Fujii N, Ohno H Suzuki Y, Naoe S, Oishi S, Fujii N, Ohno H Suzuki Y, Naoe S, Oishi S, Fujii N, Ohno H Gold-catalyzed three-component annulation: efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones. Gold-catalyzed three-component annulation: efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones. Gold-catalyzed three-component annulation: efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones. Organic letters, 14, 1, 326-329 Organic letters, 14, 1, 326-329 Organic letters, 14, 1, 326-329 2012/01 Refereed Disclose to all
Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW Buckle T, van Berg NS, Kuil J, Bunschoten A, Oldenburg J, Borowsky AD, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen FW Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist. Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist. Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist. American journal of nuclear medicine and molecular imaging, 2, 1, 99-109 American journal of nuclear medicine and molecular imaging, 2, 1, 99-109 American journal of nuclear medicine and molecular imaging, 2, 1, 99-109 2012 Refereed Disclose to all
A. Sekiya; S. Oishi; N. Fujii; T. Koide Sekiya A, Oishi S, Fujii N, Koide T A. Sekiya; S. Oishi; N. Fujii; T. Koide High-throughput turbidimetric screening for heparin-neutralizing agents and low-molecular-weight heparin mimetics High-throughput turbidimetric screening for heparin-neutralizing agents and low-molecular-weight heparin mimetics. High-throughput turbidimetric screening for heparin-neutralizing agents and low-molecular-weight heparin mimetics Chemical and Pharmaceutical Bulletin, 60, 3, 371-376 Chemical & pharmaceutical bulletin, 60, 3, 371-376 Chemical and Pharmaceutical Bulletin, 60, 3, 371-376 2012 Refereed English Disclose to all
R. Masuda; S. Oishi; N. Tanahara; H. Ohno; A. Hirasawa; G. Tsujimoto; E. Kodama; M. Matsuoka; N. Fujii Masuda Ryo, Oishi Shinya, Tanahara Noriko, Ohno Hiroaki, Hirasawa Akira, Tsujimoto Gozoh, Kodama Eiichi, Matsuoka Masao, Fujii Nobutaka R. Masuda; S. Oishi; N. Tanahara; H. Ohno; A. Hirasawa; G. Tsujimoto; E. Kodama; M. Matsuoka; N. Fujii Development and application of fluorescent SDF-1 derivatives Development and application of fluorescent SDF-1 derivatives Development and application of fluorescent SDF-1 derivatives Future Medicinal Chemistry, 4, 7, 837-844 Future Medicinal Chemistry, 4, 7, 837-844 Future Medicinal Chemistry, 4, 7, 837-844 2012 Refereed English Disclose to all
Z. Hou; Y. Suzuki; S. Oishi; N. Fujii; H. Ohno Hou Zengye, Suzuki Yamato, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Z. Hou; Y. Suzuki; S. Oishi; N. Fujii; H. Ohno Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization Tetrahedron, 68, 6, 1695-1703 Tetrahedron, 68, 6, 1695-1703 Tetrahedron, 68, 6, 1695-1703 2012 Refereed English Disclose to all
Y. Suzuki; S. Naoe; S. Oishi; N. Fujii; H. Ohno Suzuki Yamato, Naoe Saori, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Y. Suzuki; S. Naoe; S. Oishi; N. Fujii; H. Ohno Gold-catalyzed three-component annulation: Efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones Gold-Catalyzed Three-Component Annulation: Efficient Synthesis of Highly Functionalized Dihydropyrazoles from Alkynes, Hydrazines, and Aldehydes or Ketones Gold-catalyzed three-component annulation: Efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones Organic Letters, 14, 1, 326-329 Organic Letters, 14, 1, 326-329 Organic Letters, 14, 1, 326-329 2012 Refereed English Disclose to all
H. Chiba; Y. Sakai; S. Oishi; N. Fujii; H. Ohno Chiba Hiroaki, Sakai Yuki, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki H. Chiba; Y. Sakai; S. Oishi; N. Fujii; H. Ohno Lewis-acid-mediated ring-exchange reaction of dihydrobenzofurans and its application to the formal total synthesis of (-)-quinocarcinamide Lewis-acid-mediated ring-exchange reaction of dihydrobenzofurans and its application to the formal total synthesis of (-)-quinocarcinamide Lewis-acid-mediated ring-exchange reaction of dihydrobenzofurans and its application to the formal total synthesis of (-)-quinocarcinamide Tetrahedron Letters, 53, 46, 6273-6276 Tetrahedron Letters, 53, 46, 6273-6276 Tetrahedron Letters, 53, 46, 6273-6276 2012 Refereed English Disclose to all
K. Hirano; Y. Inaba; K. Takasu; S. Oishi; Y. Takemoto; N. Fujii; H. Ohno Hirano K, Inaba Y, Takasu K, Oishi S, Takemoto Y, Fujii N, Ohno H K. Hirano; Y. Inaba; K. Takasu; S. Oishi; Y. Takemoto; N. Fujii; H. Ohno Gold(I)-catalyzed polycyclizations of polyenyne-type anilines based on hydroamination and consecutive hydroarylation cascade Gold(I)-catalyzed polycyclizations of polyenyne-type anilines based on hydroamination and consecutive hydroarylation cascade. Gold(I)-catalyzed polycyclizations of polyenyne-type anilines based on hydroamination and consecutive hydroarylation cascade Journal of Organic Chemistry, 76, 21, 9068-9080 The Journal of organic chemistry, 76, 21, 9068-9080 Journal of Organic Chemistry, 76, 21, 9068-9080 2011/11 Refereed English Disclose to all
K. Nishizawa; H. Nishiyama; Y. Matsui; T. Kobayashi; R. Saito; H. Kotani; H. Masutani; S. Oishi; Y. Toda; N. Fujii; J. Yodoi; O. Ogawa Nishizawa K, Nishiyama H, Matsui Y, Kobayashi T, Saito R, Kotani H, Masutani H, Oishi S, Toda Y, Fujii N, Yodoi J, Ogawa O K. Nishizawa; H. Nishiyama; Y. Matsui; T. Kobayashi; R. Saito; H. Kotani; H. Masutani; S. Oishi; Y. Toda; N. Fujii; J. Yodoi; O. Ogawa Thioredoxin-interacting protein suppresses bladder carcinogenesis Thioredoxin-interacting protein suppresses bladder carcinogenesis. Thioredoxin-interacting protein suppresses bladder carcinogenesis Carcinogenesis, 32, 10, 1459-1466 Carcinogenesis, 32, 10, 1459-1466 Carcinogenesis, 32, 10, 1459-1466 2011/10 Refereed English Disclose to all
Y. Yoshimitsu; S. Oishi; J. Miyagaki; S. Inuki; H. Ohno; N. Fujii Yoshimitsu Y, Oishi S, Miyagaki J, Inuki S, Ohno H, Fujii N Y. Yoshimitsu; S. Oishi; J. Miyagaki; S. Inuki; H. Ohno; N. Fujii Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C. Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C Bioorganic and Medicinal Chemistry, 19, 18, 5402-5408 Bioorganic & medicinal chemistry, 19, 18, 5402-5408 Bioorganic and Medicinal Chemistry, 19, 18, 5402-5408 2011/09 Refereed English Disclose to all
K. Izumi; K. Watanabe; S. Oishi; N. Fujii; M. Matsuoka; S.G. Sarafanos; E.N. Kodama Izumi K, Watanabe K, Oishi S, Fujii N, Matsuoka M, Sarafianos SG, Kodama EN K. Izumi; K. Watanabe; S. Oishi; N. Fujii; M. Matsuoka; S.G. Sarafanos; E.N. Kodama Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effects on T-20 Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effects on T-20. Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effects on T-20 Antiviral Chemistry and Chemotherapy, 22, 1, 51-55 Antiviral chemistry & chemotherapy, 22, 1, 51-55 Antiviral Chemistry and Chemotherapy, 22, 1, 51-55 2011/08 Refereed English Disclose to all
T. Takeuchi; S. Oishi; T. Watanabe; H. Ohno; J.-I. Sawada; K. Matsuno; A. Asai; N. Asada; K. Kitaura; N. Fujii Takeuchi T, Oishi S, Watanabe T, Ohno H, Sawada J, Matsuno K, Asai A, Asada N, Kitaura K, Fujii N T. Takeuchi; S. Oishi; T. Watanabe; H. Ohno; J.-I. Sawada; K. Matsuno; A. Asai; N. Asada; K. Kitaura; N. Fujii Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors. Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors Journal of Medicinal Chemistry, 54, 13, 4839-4846 Journal of medicinal chemistry, 54, 13, 4839-4846 Journal of Medicinal Chemistry, 54, 13, 4839-4846 2011/07 Refereed English Disclose to all
A. Iwata; S. Inuki; S. Oishi; N. Fujii; H. Ohno Iwata A, Inuki S, Oishi S, Fujii N, Ohno H A. Iwata; S. Inuki; S. Oishi; N. Fujii; H. Ohno Formal total synthesis of (+)-lysergic acid via zinc(II)-mediated regioselective ring-opening reduction of 2-alkynyl-3-indolyloxirane Formal total synthesis of (+)-lysergic acid via zinc(II)-mediated regioselective ring-opening reduction of 2-alkynyl-3-indolyloxirane. Formal total synthesis of (+)-lysergic acid via zinc(II)-mediated regioselective ring-opening reduction of 2-alkynyl-3-indolyloxirane Journal of Organic Chemistry, 76, 13, 5506-5512 The Journal of organic chemistry, 76, 13, 5506-5512 Journal of Organic Chemistry, 76, 13, 5506-5512 2011/07 Refereed English Disclose to all
E. Inokuchi; S. Oishi; T. Kubo; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Inokuchi E, Oishi S, Kubo T, Ohno H, Shimura K, Matsuoka M, Fujii N E. Inokuchi; S. Oishi; T. Kubo; H. Ohno; K. Shimura; M. Matsuoka; N. Fujii Potent CXCR4 antagonists containing amidine type peptide bond isosteres Potent CXCR4 antagonists containing amidine type Peptide bond isosteres. Potent CXCR4 antagonists containing amidine type peptide bond isosteres ACS Medicinal Chemistry Letters, 2, 6, 477-480 ACS medicinal chemistry letters, 2, 6, 477-480 ACS Medicinal Chemistry Letters, 2, 6, 477-480 2011/06 Refereed English Disclose to all
R. Masuda; S. Oishi; H. Ohno; H. Kimura; H. Saji; N. Fujii Masuda R, Oishi S, Ohno H, Kimura H, Saji H, Fujii N R. Masuda; S. Oishi; H. Ohno; H. Kimura; H. Saji; N. Fujii Concise site-specific synthesis of DTPA-peptide conjugates: Application to imaging probes for the chemokine receptor CXCR4 Concise site-specific synthesis of DTPA-peptide conjugates: application to imaging probes for the chemokine receptor CXCR4. Concise site-specific synthesis of DTPA-peptide conjugates: Application to imaging probes for the chemokine receptor CXCR4 Bioorganic and Medicinal Chemistry, 19, 10, 3216-3220 Bioorganic & medicinal chemistry, 19, 10, 3216-3220 Bioorganic and Medicinal Chemistry, 19, 10, 3216-3220 2011/05 Refereed English Disclose to all
J. Kuil; T. Buckle; H. Yuan; N.S. Van Den Berg; S. Oishi; N. Fujii; L. Josephson; F.W.B. Van Leeuwen Kuil J, Buckle T, Yuan H, van den Berg NS, Oishi S, Fujii N, Josephson L, van Leeuwen FW J. Kuil; T. Buckle; H. Yuan; N.S. Van Den Berg; S. Oishi; N. Fujii; L. Josephson; F.W.B. Van Leeuwen Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide. Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide Bioconjugate Chemistry, 22, 5, 859-864 Bioconjugate chemistry, 22, 5, 859-864 Bioconjugate Chemistry, 22, 5, 859-864 2011/05 Refereed English Disclose to all
E. Inokuchi; A. Yamada; K. Hozumi; K. Tomita; S. Oishi; H. Ohno; M. Nomizu; N. Fujii Inokuchi E, Yamada A, Hozumi K, Tomita K, Oishi S, Ohno H, Nomizu M, Fujii N E. Inokuchi; A. Yamada; K. Hozumi; K. Tomita; S. Oishi; H. Ohno; M. Nomizu; N. Fujii Design and synthesis of amidine-type peptide bond isosteres: Application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis Design and synthesis of amidine-type peptide bond isosteres: application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis. Design and synthesis of amidine-type peptide bond isosteres: Application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis Organic and Biomolecular Chemistry, 9, 9, 3421-3427 Organic & biomolecular chemistry, 9, 9, 3421-3427 Organic and Biomolecular Chemistry, 9, 9, 3421-3427 2011/05 Refereed English Disclose to all
S. Inuki; A. Iwata; S. Oishi; N. Fujii; H. Ohno Inuki S, Iwata A, Oishi S, Fujii N, Ohno H S. Inuki; A. Iwata; S. Oishi; N. Fujii; H. Ohno Enantioselective total synthesis of (+)-lysergic acid, (+)-lysergol, and (+)-isolysergol by palladium-catalyzed domino cyclization of allenes bearing amino and bromoindolyl groups Enantioselective total synthesis of (+)-lysergic acid, (+)-lysergol, and (+)-isolysergol by palladium-catalyzed domino cyclization of allenes bearing amino and bromoindolyl groups. Enantioselective total synthesis of (+)-lysergic acid, (+)-lysergol, and (+)-isolysergol by palladium-catalyzed domino cyclization of allenes bearing amino and bromoindolyl groups Journal of Organic Chemistry, 76, 7, 2072-2083 The Journal of organic chemistry, 76, 7, 2072-2083 Journal of Organic Chemistry, 76, 7, 2072-2083 2011/04 Refereed English Disclose to all
H.S. Kang; T. Baba; M. Mandai; N. Matsumura; J. Hamanishi; B. Kharma; E. Kondoh; Y. Yoshioka; S. Oishi; N. Fujii; S.K. Murphy; I. Konishi Kang HS, Baba T, Mandai M, Matsumura N, Hamanishi J, Kharma B, Kondoh E, Yoshioka Y, Oishi S, Fujii N, Murphy SK, Konishi I H.S. Kang; T. Baba; M. Mandai; N. Matsumura; J. Hamanishi; B. Kharma; E. Kondoh; Y. Yoshioka; S. Oishi; N. Fujii; S.K. Murphy; I. Konishi GPR54 is a target for suppression of metastasis in endometrial cancer GPR54 is a target for suppression of metastasis in endometrial cancer. GPR54 is a target for suppression of metastasis in endometrial cancer Molecular Cancer Therapeutics, 10, 4, 580-590 Molecular cancer therapeutics, 10, 4, 580-590 Molecular Cancer Therapeutics, 10, 4, 580-590 2011/04 Refereed English Disclose to all
N.-D. Xing; S.-T. Ding; R. Saito; K. Nishizawa; T. Kobayashi; T. Inoue; S. Oishi; N. Fujii; J.-J. Lv; O. Ogawa; H. Nishiyama Xing ND, Ding ST, Saito R, Nishizawa K, Kobayashi T, Inoue T, Oishi S, Fujii N, Lv JJ, Ogawa O, Nishiyama H N.-D. Xing; S.-T. Ding; R. Saito; K. Nishizawa; T. Kobayashi; T. Inoue; S. Oishi; N. Fujii; J.-J. Lv; O. Ogawa; H. Nishiyama A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L- cysteine, a novel Eg5 inhibitor A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L-cysteine, a novel Eg5 inhibitor. A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L- cysteine, a novel Eg5 inhibitor Asian Journal of Andrology, 13, 2, 236-241 Asian journal of andrology, 13, 2, 236-241 Asian Journal of Andrology, 13, 2, 236-241 2011/03 Refereed English Disclose to all
K. Hirano; Y. Inaba; N. Takahashi; M. Shimano; S. Oishi; N. Fujii; H. Ohno Hirano K, Inaba Y, Takahashi N, Shimano M, Oishi S, Fujii N, Ohno H K. Hirano; Y. Inaba; N. Takahashi; M. Shimano; S. Oishi; N. Fujii; H. Ohno Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes. Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes Journal of Organic Chemistry, 76, 5, 1212-1227 The Journal of organic chemistry, 76, 5, 1212-1227 Journal of Organic Chemistry, 76, 5, 1212-1227 2011/03 Refereed English Disclose to all
S. Oishi; R. Misu; K. Tomita; S. Setsuda; R. Masuda; H. Ohno; Y. Naniwa; N. Ieda; N. Inoue; S. Ohkura; Y. Uenoyama; H. Tsukamura; K.-I. Maeda; A. Hirasawa; G. Tsujimoto; N. Fujii Oishi S, Misu R, Tomita K, Setsuda S, Masuda R, Ohno H, Naniwa Y, Ieda N, Inoue N, Ohkura S, Uenoyama Y, Tsukamura H, Maeda K, Hirasawa A, Tsujimoto G, Fujii N S. Oishi; R. Misu; K. Tomita; S. Setsuda; R. Masuda; H. Ohno; Y. Naniwa; N. Ieda; N. Inoue; S. Ohkura; Y. Uenoyama; H. Tsukamura; K.-I. Maeda; A. Hirasawa; G. Tsujimoto; N. Fujii Activation of neuropeptide FF receptors by kisspeptin receptor ligands Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands. Activation of neuropeptide FF receptors by kisspeptin receptor ligands ACS Medicinal Chemistry Letters, 2, 1, 53-57 ACS medicinal chemistry letters, 2, 1, 53-57 ACS Medicinal Chemistry Letters, 2, 1, 53-57 2011/01 Refereed English Disclose to all
M. Noda; Y. Omatsu; T. Sugiyama; S. Oishi; N. Fujii; T. Nagasawa Noda M, Omatsu Y, Sugiyama T, Oishi S, Fujii N, Nagasawa T M. Noda; Y. Omatsu; T. Sugiyama; S. Oishi; N. Fujii; T. Nagasawa CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice. CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice Blood, 117, 2, 451-458 Blood, 117, 2, 451-458 Blood, 117, 2, 451-458 2011/01 Refereed English Disclose to all
Y. Tokimizu; Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Tokimizu Yusuke, Ohta Yusuke, Chiba Hiroaki, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki Y. Tokimizu; Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes Tetrahedron, 67, 29, 5168-5175 Tetrahedron, 67, 29, 5168-5175 Tetrahedron, 67, 29, 5168-5175 2011 Refereed English Disclose to all
Buckle T, van den Berg N. S, Kuil J, Bunschoten A, Oldenburg J, Borowsky A. D, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen F. W. B. Buckle T, van den Berg N. S, Kuil J, Bunschoten A, Oldenburg J, Borowsky A. D, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen F. W. B. Buckle T, van den Berg N. S, Kuil J, Bunschoten A, Oldenburg J, Borowsky A. D, Wesseling J, Masada R, Oishi S, Fujii N, van Leeuwen F. W. B. Non-invasive longitudinal imaging of tumor progression using an 111Indium labeled CXCR4 peptide antagonist Non-invasive longitudinal imaging of tumor progression using an 111Indium labeled CXCR4 peptide antagonist Non-invasive longitudinal imaging of tumor progression using an 111Indium labeled CXCR4 peptide antagonist European Journal of Nuclear Medicine and Molecular Imaging, 38, S145 European Journal of Nuclear Medicine and Molecular Imaging, 38, S145 European Journal of Nuclear Medicine and Molecular Imaging, 38, S145 2011 Refereed Disclose to all
A. Dar; A. Schajnovitz; K. Lapid; A. Kalinkovich; T. Itkin; A. Ludin; W.-M. Kao; M. Battista; M. Tesio; O. Kollet; N.N. Cohen; R. Margalit; E.C. Buss; F. Baleux; S. Oishi; N. Fujii; A. Larochelle; C.E. Dunbar; H.E. Broxmeyer; P.S. Frenette; T. Lapidot Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao W-M, Battista M, Tesio M, Kollet O, Cohen N. N, Margalit R, Buss E. C, Baleux F, Oishi S, Fujii N, Larochelle A, Dunbar C. E, Broxmeyer H. E, Frenette P. S, Lapidot T. A. Dar; A. Schajnovitz; K. Lapid; A. Kalinkovich; T. Itkin; A. Ludin; W.-M. Kao; M. Battista; M. Tesio; O. Kollet; N.N. Cohen; R. Margalit; E.C. Buss; F. Baleux; S. Oishi; N. Fujii; A. Larochelle; C.E. Dunbar; H.E. Broxmeyer; P.S. Frenette; T. Lapidot Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells Leukemia, 25, 8, 1286-1296 Leukemia, 25, 8, 1286-1296 Leukemia, 25, 8, 1286-1296 2011 Refereed English Disclose to all
Kuil Joeri, Buckle Tessa, Yuan Hushan, Van den Berg Nynke S, Oishi Shinya, Fujii Nobutaka, Josephson Lee, Van Leeuwen Fijs W. B. Kuil Joeri, Buckle Tessa, Yuan Hushan, Van den Berg Nynke S, Oishi Shinya, Fujii Nobutaka, Josephson Lee, Van Leeuwen Fijs W. B. Kuil Joeri, Buckle Tessa, Yuan Hushan, Van den Berg Nynke S, Oishi Shinya, Fujii Nobutaka, Josephson Lee, Van Leeuwen Fijs W. B. Synthesis and evaluation of a dual labeled peptide for CXCR4 imaging Synthesis and evaluation of a dual labeled peptide for CXCR4 imaging Synthesis and evaluation of a dual labeled peptide for CXCR4 imaging Journal of Labelled Compounds & Radiopharmaceuticals, 54, S235 Journal of Labelled Compounds & Radiopharmaceuticals, 54, S235 Journal of Labelled Compounds & Radiopharmaceuticals, 54, S235 2011 Refereed Disclose to all
Popiel HA, Burke JR, Strittmatter WJ, Oishi S, Fujii N, Takeuchi T, Toda T, Wada K, Nagai Y Popiel HA, Burke JR, Strittmatter WJ, Oishi S, Fujii N, Takeuchi T, Toda T, Wada K, Nagai Y Popiel HA, Burke JR, Strittmatter WJ, Oishi S, Fujii N, Takeuchi T, Toda T, Wada K, Nagai Y The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases. The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases. The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases. Journal of amino acids, 2011, 265084 Journal of amino acids, 2011, 265084 Journal of amino acids, 2011, 265084 2011 Refereed Disclose to all
Kuil J, Buckle T, Yuan H, van den Berg N. S, Oishi S, Fujii N, Josephson L, van Leeuwen F. W. B. Kuil J, Buckle T, Yuan H, van den Berg N. S, Oishi S, Fujii N, Josephson L, van Leeuwen F. W. B. Kuil J, Buckle T, Yuan H, van den Berg N. S, Oishi S, Fujii N, Josephson L, van Leeuwen F. W. B. Development of a Multimodal Peptide for CXCR4 Imaging Development of a Multimodal Peptide for CXCR4 Imaging Development of a Multimodal Peptide for CXCR4 Imaging European Journal of Nuclear Medicine and Molecular Imaging, 38, S175 European Journal of Nuclear Medicine and Molecular Imaging, 38, S175 European Journal of Nuclear Medicine and Molecular Imaging, 38, S175 2011 Refereed Disclose to all
S. Gravel; C. Malouf; P.E. Boulais; Y.A. Berchiche; S. Oishi; N. Fujii; R. Leduc; D. Sinnett; N. Heveker Gravel S, Malouf C, Boulais PE, Berchiche YA, Oishi S, Fujii N, Leduc R, Sinnett D, Heveker N S. Gravel; C. Malouf; P.E. Boulais; Y.A. Berchiche; S. Oishi; N. Fujii; R. Leduc; D. Sinnett; N. Heveker The peptidomimetic CXCR4 antagonist TC14012 recruits β-arrestin to CXCR7: Roles of receptor domains The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains. The peptidomimetic CXCR4 antagonist TC14012 recruits β-arrestin to CXCR7: Roles of receptor domains Journal of Biological Chemistry, 285, 49, 37939-37943 The Journal of biological chemistry, 285, 49, 37939-37943 Journal of Biological Chemistry, 285, 49, 37939-37943 2010/12 Refereed English Disclose to all
K. Shimura; D. Nameki; K. Kajiwara; K. Watanabe; Y. Sakagami; S. Oishi; N. Fujii; M. Matsuoka; S.G. Sarafianos; E.N. Kodama Shimura K, Nameki D, Kajiwara K, Watanabe K, Sakagami Y, Oishi S, Fujii N, Matsuoka M, Sarafianos SG, Kodama EN K. Shimura; D. Nameki; K. Kajiwara; K. Watanabe; Y. Sakagami; S. Oishi; N. Fujii; M. Matsuoka; S.G. Sarafianos; E.N. Kodama Resistance profiles of novel electrostatically constrained HIV-1 fusion inhibitors Resistance profiles of novel electrostatically constrained HIV-1 fusion inhibitors. Resistance profiles of novel electrostatically constrained HIV-1 fusion inhibitors Journal of Biological Chemistry, 285, 50, 39471-39480 The Journal of biological chemistry, 285, 50, 39471-39480 Journal of Biological Chemistry, 285, 50, 39471-39480 2010/12 Refereed English Disclose to all
Y. Ohta; Y. Tokimizu; S. Oishi; N. Fujii; H. Ohno Ohta Y, Tokimizu Y, Oishi S, Fujii N, Ohno H Y. Ohta; Y. Tokimizu; S. Oishi; N. Fujii; H. Ohno Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines. Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines Organic Letters, 12, 17, 3963-3965 Organic letters, 12, 17, 3963-3965 Organic Letters, 12, 17, 3963-3965 2010/09 Refereed English Disclose to all
大石 真也 Ding S, Nishizawa K, Kobayashi T, Oishi S, Lv J, Fujii N, Ogawa O, Nishiyama H 大石 真也 A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor. A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor. A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor. J. Urol. 15/7, 314-318, 184, 3, 1175-1181 The Journal of urology, 184, 3, 1175-1181 J. Urol. 15/7, 314-318, 184, 3, 1175-1181 2010/09 Refereed English Disclose to all
K. Nishizawa; H. Nishiyama; S. Oishi; N. Tanahara; H. Kotani; Y. Mikami; Y. Toda; B.J. Evans; S.C. Peiper; R. Saito; J. Watanabe; N. Fujii; O. Ogawa Nishizawa K, Nishiyama H, Oishi S, Tanahara N, Kotani H, Mikami Y, Toda Y, Evans BJ, Peiper SC, Saito R, Watanabe J, Fujii N, Ogawa O K. Nishizawa; H. Nishiyama; S. Oishi; N. Tanahara; H. Kotani; Y. Mikami; Y. Toda; B.J. Evans; S.C. Peiper; R. Saito; J. Watanabe; N. Fujii; O. Ogawa Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4 Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4. Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4 International Journal of Cancer, 127, 5, 1180-1187 International journal of cancer. Journal international du cancer, 127, 5, 1180-1187 International Journal of Cancer, 127, 5, 1180-1187 2010/09 Refereed English Disclose to all
K. Izumi; S. Nakamura; H. Nakano; K. Shimura; Y. Sakagami; S. Oishi; S. Uchiyama; T. Ohkubo; Y. Kobayashi; N. Fujii; M. Matsuoka; E.N. Kodama Izumi K, Nakamura S, Nakano H, Shimura K, Sakagami Y, Oishi S, Uchiyama S, Ohkubo T, Kobayashi Y, Fujii N, Matsuoka M, Kodama EN K. Izumi; S. Nakamura; H. Nakano; K. Shimura; Y. Sakagami; S. Oishi; S. Uchiyama; T. Ohkubo; Y. Kobayashi; N. Fujii; M. Matsuoka; E.N. Kodama Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat. Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat Antiviral Research, 87, 2, 179-186 Antiviral research, 87, 2, 179-186 Antiviral Research, 87, 2, 179-186 2010/08 Refereed English Disclose to all
A. Okano; K. Tsukamoto; S. Kosaka; H. Maeda; S. Oishi; T. Tanaka; N. Fujii; H. Ohno Okano A, Tsukamoto K, Kosaka S, Maeda H, Oishi S, Tanaka T, Fujii N, Ohno H A. Okano; K. Tsukamoto; S. Kosaka; H. Maeda; S. Oishi; T. Tanaka; N. Fujii; H. Ohno Synthesis of fused and linked bicyclic nitrogen heterocycles by palladiumcatalyzed domino cyclization of propargyl bromides Synthesis of fused and linked bicyclic nitrogen heterocycles by palladium-catalyzed domino cyclization of propargyl bromides. Synthesis of fused and linked bicyclic nitrogen heterocycles by palladiumcatalyzed domino cyclization of propargyl bromides Chemistry - A European Journal, 16, 28, 8410-8418 Chemistry (Weinheim an der Bergstrasse, Germany), 16, 28, 8410-8418 Chemistry - A European Journal, 16, 28, 8410-8418 2010/07 Refereed English Disclose to all
S. Oishi; T. Watanabe; J.-I. Sawada; A. Asai; H. Ohno; N. Fujii Oishi S, Watanabe T, Sawada J, Asai A, Ohno H, Fujii N S. Oishi; T. Watanabe; J.-I. Sawada; A. Asai; H. Ohno; N. Fujii Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds Journal of Medicinal Chemistry, 53, 13, 5054-5058 Journal of medicinal chemistry, 53, 13, 5054-5058 Journal of Medicinal Chemistry, 53, 13, 5054-5058 2010/07 Refereed English Disclose to all
S. Inuki; Y. Yoshimitsu; S. Oishi; N. Fujii; H. Ohno Inuki S, Yoshimitsu Y, Oishi S, Fujii N, Ohno H S. Inuki; Y. Yoshimitsu; S. Oishi; N. Fujii; H. Ohno Ring-construction/stereoselective functionalization cascade: Total synthesis of pachastrissamine (Jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates. Ring-construction/stereoselective functionalization cascade: Total synthesis of pachastrissamine (Jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates Journal of Organic Chemistry, 75, 11, 3831-3842 The Journal of organic chemistry, 75, 11, 3831-3842 Journal of Organic Chemistry, 75, 11, 3831-3842 2010/06 Refereed English Disclose to all
Y. Yoshimitsu; S. Inuki; S. Oishi; N. Fujii; H. Ohno Yoshimitsu Y, Inuki S, Oishi S, Fujii N, Ohno H Y. Yoshimitsu; S. Inuki; S. Oishi; N. Fujii; H. Ohno Stereoselective divergent synthesis of four diastereomers of pachastrissamine (Jaspine B) Stereoselective divergent synthesis of four diastereomers of pachastrissamine (jaspine B). Stereoselective divergent synthesis of four diastereomers of pachastrissamine (Jaspine B) Journal of Organic Chemistry, 75, 11, 3843-3846 The Journal of organic chemistry, 75, 11, 3843-3846 Journal of Organic Chemistry, 75, 11, 3843-3846 2010/06 Refereed English Disclose to all
A. Okano; S. Oishi; T. Tanaka; N. Fujii; H. Ohno Okano A, Oishi S, Tanaka T, Fujii N, Ohno H A. Okano; S. Oishi; T. Tanaka; N. Fujii; H. Ohno Construction of linked nitrogen heterocycles by palladium(0)-catalyzed intramolecular domino cyclization of 2-alkynylaziridines bearing a 2-aminoethyl group via ring expansion with Isocyanate Construction of linked nitrogen heterocycles by palladium(0)-catalyzed intramolecular domino cyclization of 2-alkynylaziridines bearing a 2-aminoethyl group via ring expansion with isocyanate. Construction of linked nitrogen heterocycles by palladium(0)-catalyzed intramolecular domino cyclization of 2-alkynylaziridines bearing a 2-aminoethyl group via ring expansion with Isocyanate Journal of Organic Chemistry, 75, 10, 3396-3400 The Journal of organic chemistry, 75, 10, 3396-3400 Journal of Organic Chemistry, 75, 10, 3396-3400 2010/05 Refereed English Disclose to all
T. Narumi; R. Hayashi; K. Tomita; K. Kobayashi; N. Tanahara; H. Ohno; T. Naito; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Narumi T, Hayashi R, Tomita K, Kobayashi K, Tanahara N, Ohno H, Naito T, Kodama E, Matsuoka M, Oishi S, Fujii N T. Narumi; R. Hayashi; K. Tomita; K. Kobayashi; N. Tanahara; H. Ohno; T. Naito; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres. Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres Organic and Biomolecular Chemistry, 8, 3, 616-621 Organic & biomolecular chemistry, 8, 3, 616-621 Organic and Biomolecular Chemistry, 8, 3, 616-621 2010/02 Refereed English Disclose to all
OISHI SHIN'YA, FUJII NOBUTAKA 大石真也, 藤井信孝 OISHI SHIN'YA, FUJII NOBUTAKA ケモカイン受容体CXCR4とそのアンタゴニスト ケモカイン受容体CXCR4とそのアンタゴニスト ケモカイン受容体CXCR4とそのアンタゴニスト 和光純薬時報, 78, 1, 2-5 和光純薬時報, 78, 1, 2-5 和光純薬時報, 78, 1, 2-5 2010/01/15 Japanese Disclose to all
T. Mizuhara; S. Oishi; N. Fujii; H. Ohno Mizuhara T, Oishi S, Fujii N, Ohno H T. Mizuhara; S. Oishi; N. Fujii; H. Ohno Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by S<sub>N</sub>Ar-type C-S, C-N, or C-O bond formation with heterocumulenes Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by S(N)Ar-type C-S, C-N, or C-O bond formation with heterocumulenes. Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by S<sub>N</sub>Ar-type C-S, C-N, or C-O bond formation with heterocumulenes Journal of Organic Chemistry, 75, 1, 265-268 The Journal of organic chemistry, 75, 1, 265-268 Journal of Organic Chemistry, 75, 1, 265-268 2010/01 Refereed English Disclose to all
S. Oishi; K. Watanabe; S. Ito; M. Tanaka; H. Nishikawa; H. Ohno; K. Shimane; K. Izumi; Y. Sakagami; E.N. Kodama; M. Matsuoka; A. Asai; N. Fujii Oishi Shinya, Watanabe Kentaro, Ito Saori, Tanaka Michinori, Nishikawa Hiroki, Ohno Hiroaki, Shimane Kazuki, Izumi Kazuki, Sakagami Yasuko, Kodama Eiichi N, Matsuoka Masao, Asai Akira, Fujii Nobutaka S. Oishi; K. Watanabe; S. Ito; M. Tanaka; H. Nishikawa; H. Ohno; K. Shimane; K. Izumi; Y. Sakagami; E.N. Kodama; M. Matsuoka; A. Asai; N. Fujii Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants MedChemComm, 1, 4, 276-281 Medchemcomm, 1, 4, 276-281 MedChemComm, 1, 4, 276-281 2010 Refereed English Disclose to all
K. Hirano; Y. Inaba; T. Watanabe; S. Oishi; N. Fujii; H. Ohno Hirano Kimio, Inaba Yusuke, Watanabe Toshiaki, Oishi Shinya, Fujii Nobutaka, Ohno Hiroaki K. Hirano; Y. Inaba; T. Watanabe; S. Oishi; N. Fujii; H. Ohno Gold-catalyzed intramolecular alkyne cycloisomerization cascade: Direct synthesis of aryl-annulated[a]carbazoles from aniline-substituted diethynylarenes Gold-Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl-Annulated[a]carbazoles from Aniline-Substituted Diethynylarenes Gold-catalyzed intramolecular alkyne cycloisomerization cascade: Direct synthesis of aryl-annulated[a]carbazoles from aniline-substituted diethynylarenes Advanced Synthesis and Catalysis, 352, 2/3, 368-372 Advanced Synthesis & Catalysis, 352, 2/3, 368-372 Advanced Synthesis and Catalysis, 352, 2/3, 368-372 2010 Refereed English Disclose to all
Inoue Naoko, Sasaki Yuki, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Tsukamura Hiroko, Maeda Kei-ichiro Inoue Naoko, Sasaki Yuki, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Tsukamura Hiroko, Maeda Kei-ichiro Inoue Naoko, Sasaki Yuki, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Tsukamura Hiroko, Maeda Kei-ichiro Induction of ovulation by kisspeptin and its agonists in the musk shrew (Suncus murinus), a reflex ovulator Induction of ovulation by kisspeptin and its agonists in the musk shrew (Suncus murinus), a reflex ovulator Induction of ovulation by kisspeptin and its agonists in the musk shrew (Suncus murinus), a reflex ovulator Endocrine Journal, 57, S517 Endocrine Journal, 57, S517 Endocrine Journal, 57, S517 2010 Refereed Disclose to all
Inoue Naoko, Tomikawa Junko, Sasaki Yuki, Uchida Akira, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Maeda Keiichiro, Tsukamura Hiroko Inoue Naoko, Tomikawa Junko, Sasaki Yuki, Uchida Akira, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Maeda Keiichiro, Tsukamura Hiroko Inoue Naoko, Tomikawa Junko, Sasaki Yuki, Uchida Akira, Oishi Shinya, Fujii Nobutaka, Uenoyama Yoshihisa, Yamamoto Naoyuki, Maeda Keiichiro, Tsukamura Hiroko Kiss1 cDNA Cloning and Induction of Ovulation by Peripheral Administration of Various Kisspeptins in the Musk Shrew (Suncus murinus), a Reflex Ovulator. Kiss1 cDNA Cloning and Induction of Ovulation by Peripheral Administration of Various Kisspeptins in the Musk Shrew (Suncus murinus), a Reflex Ovulator. Kiss1 cDNA Cloning and Induction of Ovulation by Peripheral Administration of Various Kisspeptins in the Musk Shrew (Suncus murinus), a Reflex Ovulator. Biology of Reproduction, 172 Biology of Reproduction, 172 Biology of Reproduction, 172 2010 Refereed Disclose to all
K. Kajiwara; K. Watanabe; R. Tokiwa; T. Kurose; H. Ohno; H. Tsutsumi; Y. Hata; K. Izumi; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Kajiwara K, Watanabe K, Tokiwa R, Kurose T, Ohno H, Tsutsumi H, Hata Y, Izumi K, Kodama E, Matsuoka M, Oishi S, Fujii N K. Kajiwara; K. Watanabe; R. Tokiwa; T. Kurose; H. Ohno; H. Tsutsumi; Y. Hata; K. Izumi; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group. Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group Bioorganic and Medicinal Chemistry, 17, 23, 7964-7970 Bioorganic & medicinal chemistry, 17, 23, 7964-7970 Bioorganic and Medicinal Chemistry, 17, 23, 7964-7970 2009/12 Refereed English Disclose to all
M. Tanaka; K. Kajiwara; R. Tokiwa; K. Watanabe; H. Ohno; H. Tsutsumi; Y. Hata; K. Izumi; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Tanaka M, Kajiwara K, Tokiwa R, Watanabe K, Ohno H, Tsutsumi H, Hata Y, Izumi K, Kodama E, Matsuoka M, Oishi S, Fujii N M. Tanaka; K. Kajiwara; R. Tokiwa; K. Watanabe; H. Ohno; H. Tsutsumi; Y. Hata; K. Izumi; E. Kodama; M. Matsuoka; S. Oishi; N. Fujii Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins. Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins Bioorganic and Medicinal Chemistry, 17, 21, 7487-7492 Bioorganic & medicinal chemistry, 17, 21, 7487-7492 Bioorganic and Medicinal Chemistry, 17, 21, 7487-7492 2009/11 Refereed English Disclose to all
S. Lnuki; Y. Yoshimitsu; S. Oishi; N. Fujii; H. Ohno Inuki S, Yoshimitsu Y, Oishi S, Fujii N, Ohno H S. Lnuki; Y. Yoshimitsu; S. Oishi; N. Fujii; H. Ohno Ring-construction/stereoselective functionalization cascade: Total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of bromoallenes Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of bromoallenes. Ring-construction/stereoselective functionalization cascade: Total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of bromoallenes Organic Letters, 11, 19, 4478-4481 Organic letters, 11, 19, 4478-4481 Organic Letters, 11, 19, 4478-4481 2009/10 Refereed English Disclose to all
T. Tanaka; W. Nomura; T. Narumi; A. Esaka; S. Oishi; N. Ohashi; K. Itotani; B.J. Evans; Z.-X. Wang; S.C. Peiper; N. Fujii; H. Tamamura Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H T. Tanaka; W. Nomura; T. Narumi; A. Esaka; S. Oishi; N. Ohashi; K. Itotani; B.J. Evans; Z.-X. Wang; S.C. Peiper; N. Fujii; H. Tamamura Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: The exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: The exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids Organic and Biomolecular Chemistry, 7, 18, 3805-3809 Organic & biomolecular chemistry, 7, 18, 3805-3809 Organic and Biomolecular Chemistry, 7, 18, 3805-3809 2009/09 Refereed English Disclose to all
Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Ohta Y, Chiba H, Oishi S, Fujii N, Ohno H Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization. Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization Journal of Organic Chemistry, 74, 18, 7052-7058 The Journal of organic chemistry, 74, 18, 7052-7058 Journal of Organic Chemistry, 74, 18, 7052-7058 2009/09 Refereed English Disclose to all
T. Watabe; Y. Terakawa; K. Watanabe; H. Ohno; H. Nakano; T. Nakatsu; H. Kato; K. Izumi; E. Kodama; M. Matsuoka; K. Kitaura; S. Oishi; N. Fujii Watabe T, Terakawa Y, Watanabe K, Ohno H, Nakano H, Nakatsu T, Kato H, Izumi K, Kodama E, Matsuoka M, Kitaura K, Oishi S, Fujii N T. Watabe; Y. Terakawa; K. Watanabe; H. Ohno; H. Nakano; T. Nakatsu; H. Kato; K. Izumi; E. Kodama; M. Matsuoka; K. Kitaura; S. Oishi; N. Fujii X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution X-ray crystallographic study of an HIV-1 fusion inhibitor with the gp41 S138A substitution. X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution Journal of Molecular Biology, 392, 3, 657-665 Journal of molecular biology, 392, 3, 657-665 Journal of Molecular Biology, 392, 3, 657-665 2009/09 Refereed English Disclose to all
Y. Ohta; Y. Kubota; T. Watabe; H. Chiba; S. Oishi; N. Fujii; H. Ohno Ohta Y, Kubota Y, Watabe T, Chiba H, Oishi S, Fujii N, Ohno H Y. Ohta; Y. Kubota; T. Watabe; H. Chiba; S. Oishi; N. Fujii; H. Ohno Rapid access to 3-(aminomethyl)isoquinoline-fused polycyclic compounds by copper-catalyzed four-component coupling, cascade cyclization, and oxidation Rapid access to 3-(aminomethyl)isoquinoline-fused polycyclic compounds by copper-catalyzed four-component coupling, cascade cyclization, and oxidation. Rapid access to 3-(aminomethyl)isoquinoline-fused polycyclic compounds by copper-catalyzed four-component coupling, cascade cyclization, and oxidation Journal of Organic Chemistry, 74, 16, 6299-6302 The Journal of organic chemistry, 74, 16, 6299-6302 Journal of Organic Chemistry, 74, 16, 6299-6302 2009/08 Refereed English Disclose to all
S. Oishi; H. Kamitani; Y. Kodera; K. Watanabe; K. Kobayashi; T. Narumi; K. Tomita; H. Ohno; T. Naito; E. Kodama; M. Matsuoka; N. Fujii Oishi S, Kamitani H, Kodera Y, Watanabe K, Kobayashi K, Narumi T, Tomita K, Ohno H, Naito T, Kodama E, Matsuoka M, Fujii N S. Oishi; H. Kamitani; Y. Kodera; K. Watanabe; K. Kobayashi; T. Narumi; K. Tomita; H. Ohno; T. Naito; E. Kodama; M. Matsuoka; N. Fujii Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: Synthesis and bioevaluation of α-helical anti-HIV peptide analogues Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues. Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: Synthesis and bioevaluation of α-helical anti-HIV peptide analogues Organic and Biomolecular Chemistry, 7, 14, 2872-2877 Organic & biomolecular chemistry, 7, 14, 2872-2877 Organic and Biomolecular Chemistry, 7, 14, 2872-2877 2009/07 Refereed English Disclose to all
S. Oishi; Y. Kodera; H. Nishikawa; H. Kamitani; T. Watabe; H. Ohno; T. Tochikura; K. Shimane; E. Kodama; M. Matsuoka; F. Mizukoshi; H. Tsujimoto; N. Fujii Oishi S, Kodera Y, Nishikawa H, Kamitani H, Watabe T, Ohno H, Tochikura T, Shimane K, Kodama E, Matsuoka M, Mizukoshi F, Tsujimoto H, Fujii N S. Oishi; Y. Kodera; H. Nishikawa; H. Kamitani; T. Watabe; H. Ohno; T. Tochikura; K. Shimane; E. Kodama; M. Matsuoka; F. Mizukoshi; H. Tsujimoto; N. Fujii Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus. Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus Bioorganic and Medicinal Chemistry, 17, 14, 4916-4920 Bioorganic & medicinal chemistry, 17, 14, 4916-4920 Bioorganic and Medicinal Chemistry, 17, 14, 4916-4920 2009/07 Refereed English Disclose to all
T. Watanabe; S. Oishi; N. Fujii; H. Ohno Watanabe T, Oishi S, Fujii N, Ohno H T. Watanabe; S. Oishi; N. Fujii; H. Ohno Palladium-catalyzed direct synthesis of carbazoles via one-pot N-arylation and oxidative biaryl coupling: Synthesis and mechanistic study Palladium-catalyzed direct synthesis of carbazoles via one-pot N-arylation and oxidative biaryl coupling: synthesis and mechanistic study. Palladium-catalyzed direct synthesis of carbazoles via one-pot N-arylation and oxidative biaryl coupling: Synthesis and mechanistic study Journal of Organic Chemistry, 74, 13, 4720-4726 The Journal of organic chemistry, 74, 13, 4720-4726 Journal of Organic Chemistry, 74, 13, 4720-4726 2009/07 Refereed English Disclose to all
T. Mizuhara; S. Inuki; S. Oishi; N. Fujii; H. Ohno Mizuhara T, Inuki S, Oishi S, Fujii N, Ohno H T. Mizuhara; S. Inuki; S. Oishi; N. Fujii; H. Ohno Cu(ii)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group Cu(II)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group. Cu(ii)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group Chemical Communications, 23, 3413-3415 Chemical communications (Cambridge, England), 23, 3413-3415 Chemical Communications, 23, 3413-3415 2009/06 Refereed English Disclose to all
K. Kobayashi; T. Narumi; S. Oishi; H. Ohno; N. Fujii Kobayashi K, Narumi T, Oishi S, Ohno H, Fujii N K. Kobayashi; T. Narumi; S. Oishi; H. Ohno; N. Fujii Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper- mediated S<sub>N</sub>2′ alkylation Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper-mediated S(N)2' alkylation. Amino acid-based synthesis of trifluoromethylalkene dipeptide isosteres by alcohol-assisted nucleophilic trifluoromethylation and organozinc-copper- mediated S<sub>N</sub>2′ alkylation Journal of Organic Chemistry, 74, 12, 4626-4629 The Journal of organic chemistry, 74, 12, 4626-4629 Journal of Organic Chemistry, 74, 12, 4626-4629 2009/06 Refereed English Disclose to all
Y. Suzuki; Y. Ohta; S. Oishi; N. Fujii; H. Ohno Suzuki Y, Ohta Y, Oishi S, Fujii N, Ohno H Y. Suzuki; Y. Ohta; S. Oishi; N. Fujii; H. Ohno Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization. Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization Journal of Organic Chemistry, 74, 11, 4246-4251 The Journal of organic chemistry, 74, 11, 4246-4251 Journal of Organic Chemistry, 74, 11, 4246-4251 2009/06 Refereed English Disclose to all
Y. Ohta; S. Oishi; N. Fujii; H. Ohno Ohta Y, Oishi S, Fujii N, Ohno H Y. Ohta; S. Oishi; N. Fujii; H. Ohno Facile synthesis of 1,2,3,4-tetrahydro-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization Facile synthesis of 1,2,3,4-tetrahydro-beta-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization. Facile synthesis of 1,2,3,4-tetrahydro-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization Organic Letters, 11, 9, 1979-1982 Organic letters, 11, 9, 1979-1982 Organic Letters, 11, 9, 1979-1982 2009/05 Refereed English Disclose to all
M. Ueno; E.N. Kodama; K. Shimura; Y. Sakurai; K. Kajiwara; Y. Sakagami; S. Oishi; N. Fujii; M. Matsuoka Ueno M, Kodama EN, Shimura K, Sakurai Y, Kajiwara K, Sakagami Y, Oishi S, Fujii N, Matsuoka M M. Ueno; E.N. Kodama; K. Shimura; Y. Sakurai; K. Kajiwara; Y. Sakagami; S. Oishi; N. Fujii; M. Matsuoka Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide. Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide Antiviral Research, 82, 1, 67-72 Antiviral research, 82, 1, 67-72 Antiviral Research, 82, 1, 67-72 2009/04 Refereed English Disclose to all
H. Shim; S. Oishi; N. Fujii Shim H, Oishi S, Fujii N H. Shim; S. Oishi; N. Fujii Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors. Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors Seminars in Cancer Biology, 19, 2, 123-134 Seminars in cancer biology, 19, 2, 123-134 Seminars in Cancer Biology, 19, 2, 123-134 2009/04 Refereed English Disclose to all
F. Mizukoshi; K. Baba; Y. Goto; A. Setoguchi; Y. Fujino; K. Ohno; S. Oishi; Y. Kodera; N. Fujii; H. Tsujimoto Mizukoshi F, Baba K, Goto Y, Setoguchi A, Fujino Y, Ohno K, Oishi S, Kodera Y, Fujii N, Tsujimoto H F. Mizukoshi; K. Baba; Y. Goto; A. Setoguchi; Y. Fujino; K. Ohno; S. Oishi; Y. Kodera; N. Fujii; H. Tsujimoto Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein. Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein Veterinary Microbiology, 136, 1/2, 155-159 Veterinary microbiology, 136, 1/2, 155-159 Veterinary Microbiology, 136, 1/2, 155-159 2009/04 Refereed English Disclose to all
H. Nishikawa; S. Nakamura; E. Kodama; S. Ito; K. Kajiwara; K. Izumi; Y. Sakagami; S. Oishi; T. Ohkubo; Y. Kobayashi; A. Otaka; N. Fujii; M. Matsuoka Nishikawa H, Nakamura S, Kodama E, Ito S, Kajiwara K, Izumi K, Sakagami Y, Oishi S, Ohkubo T, Kobayashi Y, Otaka A, Fujii N, Matsuoka M H. Nishikawa; S. Nakamura; E. Kodama; S. Ito; K. Kajiwara; K. Izumi; Y. Sakagami; S. Oishi; T. Ohkubo; Y. Kobayashi; A. Otaka; N. Fujii; M. Matsuoka Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide Electrostatically constrained alpha-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide. Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide International Journal of Biochemistry and Cell Biology, 41, 4, 891-899 The international journal of biochemistry & cell biology, 41, 4, 891-899 International Journal of Biochemistry and Cell Biology, 41, 4, 891-899 2009/04 Refereed English Disclose to all
T. Kitaori; H. Ito; E.M. Schwarz; R. Tsutsumi; H. Yoshitomi; S. Oishi; M. Nakano; N. Fujii; T. Nagasawa; T. Nakamura Kitaori T, Ito H, Schwarz EM, Tsutsumi R, Yoshitomi H, Oishi S, Nakano M, Fujii N, Nagasawa T, Nakamura T T. Kitaori; H. Ito; E.M. Schwarz; R. Tsutsumi; H. Yoshitomi; S. Oishi; M. Nakano; N. Fujii; T. Nagasawa; T. Nakamura Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model Arthritis and Rheumatism, 60, 3, 813-823 Arthritis and rheumatism, 60, 3, 813-823 Arthritis and Rheumatism, 60, 3, 813-823 2009/03 Refereed English Disclose to all
F. Katagiri; K. Nagai; A. Kida; K. Tomita; S. Oishi; M. Takeyama; R. Doi; N. Fujii Katagiri F, Nagai K, Kida A, Tomita K, Oishi S, Takeyama M, Doi R, Fujii N F. Katagiri; K. Nagai; A. Kida; K. Tomita; S. Oishi; M. Takeyama; R. Doi; N. Fujii Clinical significance of plasma metastin level in pancreatic cancer patients Clinical significance of plasma metastin level in pancreatic cancer patients. Clinical significance of plasma metastin level in pancreatic cancer patients Oncology Reports, 21, 3, 815-819 Oncology reports, 21, 3, 815-819 Oncology Reports, 21, 3, 815-819 2009/03 Refereed English Disclose to all
T. Naito; K. Izumi; E. Kodama; H. Nishikawa; K. Watanabe; Y. Sakagami; K. Kajiwara; S.G. Sarafianos; S. Oishi; N. Fujii; M. Matsuoka Naito T, Izumi K, Kodama E, Sakagami Y, Kajiwara K, Nishikawa H, Watanabe K, Sarafianos SG, Oishi S, Fujii N, Matsuoka M T. Naito; K. Izumi; E. Kodama; H. Nishikawa; K. Watanabe; Y. Sakagami; K. Kajiwara; S.G. Sarafianos; S. Oishi; N. Fujii; M. Matsuoka SC29EK, a peptide fusion inhibitor with enhanced α-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide. SC29EK, a peptide fusion inhibitor with enhanced α-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide Antimicrobial Agents and Chemotherapy, 53, 3, 1013-1018 Antimicrobial agents and chemotherapy, 53, 3, 1013-1018 Antimicrobial Agents and Chemotherapy, 53, 3, 1013-1018 2009/03 Refereed English Disclose to all
K. Tomita; H.A. Popiel; Y. Nagai; T. Toda; Y. Yoshimitsu; H. Ohno; S. Oishi; N. Fujii Tomita K, Popiel HA, Nagai Y, Toda T, Yoshimitsu Y, Ohno H, Oishi S, Fujii N K. Tomita; H.A. Popiel; Y. Nagai; T. Toda; Y. Yoshimitsu; H. Ohno; S. Oishi; N. Fujii Structure-activity relationship study on polyglutamine binding peptide QBP1 Structure-activity relationship study on polyglutamine binding peptide QBP1. Structure-activity relationship study on polyglutamine binding peptide QBP1 Bioorganic and Medicinal Chemistry, 17, 3, 1259-1263 Bioorganic & medicinal chemistry, 17, 3, 1259-1263 Bioorganic and Medicinal Chemistry, 17, 3, 1259-1263 2009/02 Refereed English Disclose to all
K. Izumi; E. Kodama; K. Shimura; Y. Sakagami; K. Watanabe; S. Ito; T. Watabe; Y. Terakawa; H. Nishikawa; S.G. Sarafianos; K. Kitaura; S. Oishi; N. Fujii; M. Matsuoka Izumi K, Kodama E, Shimura K, Sakagami Y, Watanabe K, Ito S, Watabe T, Terakawa Y, Nishikawa H, Sarafianos SG, Kitaura K, Oishi S, Fujii N, Matsuoka M K. Izumi; E. Kodama; K. Shimura; Y. Sakagami; K. Watanabe; S. Ito; T. Watabe; Y. Terakawa; H. Nishikawa; S.G. Sarafianos; K. Kitaura; S. Oishi; N. Fujii; M. Matsuoka Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20 Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20. Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20 Journal of Biological Chemistry, 284, 8, 4914-4920 The Journal of biological chemistry, 284, 8, 4914-4920 Journal of Biological Chemistry, 284, 8, 4914-4920 2009/02 Refereed English Disclose to all
大石 真也 Mizukoshi F, Baba K, Goto-Koshino Y, Setoguchi-Mukai A, Fujino Y, Ohno K, Tamamura H, Oishi S, Fujii N, Tsujimoto H 大石 真也 Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus. Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus. Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus. Vet. Microbiol. 136/1-2, 155-159, 71, 1, 121-124 The Journal of veterinary medical science / the Japanese Society of Veterinary Science, 71, 1, 121-124 Vet. Microbiol. 136/1-2, 155-159, 71, 1, 121-124 2009/01 Refereed English Disclose to all
K. Nagai; R. Doi; F. Katagiri; T. Ito; A. Kida; M. Koizumi; T. Masui; Y. Kawaguchi; K. Tomita; S. Oishi; N. Fujii; S. Uemoto Nagai K, Doi R, Katagiri F, Ito T, Kida A, Koizumi M, Masui T, Kawaguchi Y, Tomita K, Oishi S, Fujii N, Uemoto S K. Nagai; R. Doi; F. Katagiri; T. Ito; A. Kida; M. Koizumi; T. Masui; Y. Kawaguchi; K. Tomita; S. Oishi; N. Fujii; S. Uemoto Prognostic value of metastin expression in human pancreatic cancer Prognostic value of metastin expression in human pancreatic cancer. Prognostic value of metastin expression in human pancreatic cancer Journal of Experimental and Clinical Cancer Research, 28, 1 Journal of experimental & clinical cancer research : CR, 28, 1 Journal of Experimental and Clinical Cancer Research, 28, 1 2009/01 Refereed English Disclose to all
Mizukoshi Fuminori, Baba Kenji, Goto-Koshino Yuko, Setoguchi-Mukai Asuka, Fujino Yasuhito, Ohno Koichi, Tamamura Hirokazu, Oishi Shinya, Fujii Nobutaka, Tsujimoto Hajime Mizukoshi Fuminori, Baba Kenji, Goto-Koshino Yuko, Setoguchi-Mukai Asuka, Fujino Yasuhito, Ohno Koichi, Tamamura Hirokazu, Oishi Shinya, Fujii Nobutaka, Tsujimoto Hajime Mizukoshi Fuminori, Baba Kenji, Goto-Koshino Yuko, Setoguchi-Mukai Asuka, Fujino Yasuhito, Ohno Koichi, Tamamura Hirokazu, Oishi Shinya, Fujii Nobutaka, Tsujimoto Hajime Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus Journal of Veterinary Medical Science, 71, 1, 121-124 Journal of Veterinary Medical Science, 71, 1, 121-124 Journal of Veterinary Medical Science, 71, 1, 121-124 2009 Refereed Disclose to all
B.J. Evans; Z. Wang; J.R. Broach; S. Oishi; N. Fujii; S.C. Peiper Evans BJ, Wang Z, Broach JR, Oishi S, Fujii N, Peiper SC B.J. Evans; Z. Wang; J.R. Broach; S. Oishi; N. Fujii; S.C. Peiper Chapter 20 Expression of CXCR4, a G-Protein-Coupled Receptor for CXCL12 in Yeast. Identification of New-Generation Inverse Agonists Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists. Chapter 20 Expression of CXCR4, a G-Protein-Coupled Receptor for CXCL12 in Yeast. Identification of New-Generation Inverse Agonists Methods in Enzymology, 460, 399-412 Methods in enzymology, 460, 399-412 Methods in Enzymology, 460, 399-412 2009 Refereed English Disclose to all
S. Oishi; S. Ito; H. Nishikawa; M. Tanaka; H. Ohno; A. Otaka; K. Izumi; E. Kodama; M. Matsuoka; N. Fujii Oishi S, Ito S, Nishikawa H, Tanaka M, Ohno H, Otaka A, Izumi K, Kodama E, Matsuoka M, Fujii N S. Oishi; S. Ito; H. Nishikawa; M. Tanaka; H. Ohno; A. Otaka; K. Izumi; E. Kodama; M. Matsuoka; N. Fujii Development of a novel fusion inhibitor against T-20-resistant HIV-1. Development of a novel fusion inhibitor against T-20-resistant HIV-1. Development of a novel fusion inhibitor against T-20-resistant HIV-1. Advances in experimental medicine and biology, 611, 389-391 Advances in experimental medicine and biology, 611, 389-391 Advances in experimental medicine and biology, 611, 389-391 2009 Refereed English Disclose to all
K. Tomita; T. Narumi; A. Niida; S. Oishi; H. Ohno; N. Fujii Tomita K, Narumi T, Niida A, Oishi S, Ohno H, Fujii N K. Tomita; T. Narumi; A. Niida; S. Oishi; H. Ohno; N. Fujii Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents. Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents. Synthesis and application of (Z)-alkene- and (E)-fluoroalkene-dipeptide isosteres as cis-amide equivalents. Advances in experimental medicine and biology, 611, 365-366 Advances in experimental medicine and biology, 611, 365-366 Advances in experimental medicine and biology, 611, 365-366 2009 Refereed English Disclose to all
S. Takaki; K. Kato-Takagaki; N. Suzuki; S. Oishi; Y. Kikkawa; M. Nomizu Takaki S, Kato-Takagaki K, Suzuki N, Oishi S, Kikkawa Y, Nomizu M S. Takaki; K. Kato-Takagaki; N. Suzuki; S. Oishi; Y. Kikkawa; M. Nomizu Cyclic peptide analogs of laminin active sequences enhance the biological activity. Cyclic peptide analogs of laminin active sequences enhance the biological activity. Cyclic peptide analogs of laminin active sequences enhance the biological activity. Advances in experimental medicine and biology, 611, 297-298 Advances in experimental medicine and biology, 611, 297-298 Advances in experimental medicine and biology, 611, 297-298 2009 Refereed English Disclose to all
Tamamura H, Tanaka T, Tsutsumi H, Nemoto K, Mizokami S, Ohashi N, Oishi S, Fujii N Tamamura H, Tanaka T, Tsutsumi H, Nemoto K, Mizokami S, Ohashi N, Oishi S, Fujii N Tamamura H, Tanaka T, Tsutsumi H, Nemoto K, Mizokami S, Ohashi N, Oishi S, Fujii N Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. Advances in experimental medicine and biology, 611, 149-150 Advances in experimental medicine and biology, 611, 149-150 Advances in experimental medicine and biology, 611, 149-150 2009 Refereed English Disclose to all
H. Tamamura; T. Tanaka; H. Tsutsumi; N. Ohashi; K. Hiramatsu; T. Araki; A. Ojida; I. Hamachi; Z. Wang; S.C. Peiper; J.O. Trent; S. Ueda; S. Oishi; N. Fujii Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N H. Tamamura; T. Tanaka; H. Tsutsumi; N. Ohashi; K. Hiramatsu; T. Araki; A. Ojida; I. Hamachi; Z. Wang; S.C. Peiper; J.O. Trent; S. Ueda; S. Oishi; N. Fujii Development of chemokine receptor cxcr4 antagonists using bio-mimetic strategy Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy. Development of chemokine receptor cxcr4 antagonists using bio-mimetic strategy Advances in Experimental Medicine and Biology, 611, 145-146 Advances in experimental medicine and biology, 611, 145-146 Advances in Experimental Medicine and Biology, 611, 145-146 2009 Refereed English Disclose to all
K. Tomita; S. Oishi; H. Ohno; S.C. Peiper; N. Fujii Tomita K, Oishi S, Ohno H, Peiper SC, Fujii N K. Tomita; S. Oishi; H. Ohno; S.C. Peiper; N. Fujii Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase. Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase Journal of Medicinal Chemistry, 51, 23, 7645-7649 Journal of medicinal chemistry, 51, 23, 7645-7649 Journal of Medicinal Chemistry, 51, 23, 7645-7649 2008/12 Refereed English Disclose to all
S. Inuki; S. Oishi; N. Fujii; H. Ohno Inuki S, Oishi S, Fujii N, Ohno H S. Inuki; S. Oishi; N. Fujii; H. Ohno Total synthesis of (±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group Total synthesis of (+/-)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group. Total synthesis of (±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group Organic Letters, 10, 22, 5239-5242 Organic letters, 10, 22, 5239-5242 Organic Letters, 10, 22, 5239-5242 2008/11 Refereed English Disclose to all
S. Mikami; H. Nakase; S. Yamamoto; Y. Takeda; T. Yoshino; K. Kasahara; S. Ueno; N. Uza; S. Oishi; N. Fujii; T. Nagasawa; T. Chiba Mikami S, Nakase H, Yamamoto S, Takeda Y, Yoshino T, Kasahara K, Ueno S, Uza N, Oishi S, Fujii N, Nagasawa T, Chiba T S. Mikami; H. Nakase; S. Yamamoto; Y. Takeda; T. Yoshino; K. Kasahara; S. Ueno; N. Uza; S. Oishi; N. Fujii; T. Nagasawa; T. Chiba Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis. Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis Journal of Pharmacology and Experimental Therapeutics, 327, 2, 383-392 The Journal of pharmacology and experimental therapeutics, 327, 2, 383-392 Journal of Pharmacology and Experimental Therapeutics, 327, 2, 383-392 2008/11 Refereed English Disclose to all
H. Nishikawa; S. Oishi; M. Fujita; K. Watanabe; R. Tokiwa; H. Ohno; E. Kodama; K. Izumi; K. Kajiwara; T. Naitoh; M. Matsuoka; A. Otaka; N. Fujii Nishikawa H, Oishi S, Fujita M, Watanabe K, Tokiwa R, Ohno H, Kodama E, Izumi K, Kajiwara K, Naitoh T, Matsuoka M, Otaka A, Fujii N H. Nishikawa; S. Oishi; M. Fujita; K. Watanabe; R. Tokiwa; H. Ohno; E. Kodama; K. Izumi; K. Kajiwara; T. Naitoh; M. Matsuoka; A. Otaka; N. Fujii Identification of minimal sequence for HIV-1 fusion inhibitors Identification of minimal sequence for HIV-1 fusion inhibitors. Identification of minimal sequence for HIV-1 fusion inhibitors Bioorganic and Medicinal Chemistry, 16, 20, 9184-9187 Bioorganic & medicinal chemistry, 16, 20, 9184-9187 Bioorganic and Medicinal Chemistry, 16, 20, 9184-9187 2008/10 Refereed English Disclose to all
H. Nishikawa; E. Kodama; A. Sakakibara; A. Fukudome; K. Izumi; S. Oishi; N. Fujii; M. Matsuoka Nishikawa H, Kodama E, Sakakibara A, Fukudome A, Izumi K, Oishi S, Fujii N, Matsuoka M H. Nishikawa; E. Kodama; A. Sakakibara; A. Fukudome; K. Izumi; S. Oishi; N. Fujii; M. Matsuoka Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41 Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41. Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41 Antiviral Research, 80, 1, 71-76 Antiviral research, 80, 1, 71-76 Antiviral Research, 80, 1, 71-76 2008/10 Refereed English Disclose to all
Y. Suzuki; J. Cluzeau; T. Hara; A. Hirasawa; G. Tsujimoto; S. Oishi; H. Ohno; N. Fujii Suzuki Y, Cluzeau J, Hara T, Hirasawa A, Tsujimoto G, Oishi S, Ohno H, Fujii N Y. Suzuki; J. Cluzeau; T. Hara; A. Hirasawa; G. Tsujimoto; S. Oishi; H. Ohno; N. Fujii Structure-activity relationships of pyrazine-based CK2 inhibitors: Synthesis and evaluation of 2,6-disubstituted pyrazines and 4,6-disubstituted pyrimidines Structure-activity relationships of pyrazine-based CK2 inhibitors: synthesis and evaluation of 2,6-disubstituted pyrazines and 4,6-disubstituted pyrimidines. Structure-activity relationships of pyrazine-based CK2 inhibitors: Synthesis and evaluation of 2,6-disubstituted pyrazines and 4,6-disubstituted pyrimidines Archiv der Pharmazie, 341, 9, 554-561 Archiv der Pharmazie, 341, 9, 554-561 Archiv der Pharmazie, 341, 9, 554-561 2008/09 Refereed English Disclose to all
A. Okano; T. Mizutani; S. Oishi; T. Tanaka; H. Ohno; N. Fujii Okano A, Mizutani T, Oishi S, Tanaka T, Ohno H, Fujii N A. Okano; T. Mizutani; S. Oishi; T. Tanaka; H. Ohno; N. Fujii Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade. Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade Chemical Communications, 30, 3534-3536 Chemical communications (Cambridge, England), 30, 3534-3536 Chemical Communications, 30, 3534-3536 2008/08 Refereed English Disclose to all
Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Ohta Y, Chiba H, Oishi S, Fujii N, Ohno H Y. Ohta; H. Chiba; S. Oishi; N. Fujii; H. Ohno Concise synthesis of indole-fused 1,4-diazepines through copper(l)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation Concise synthesis of indole-fused 1,4-diazepines through copper(I)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation. Concise synthesis of indole-fused 1,4-diazepines through copper(l)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation Organic Letters, 10, 16, 3535-3538 Organic letters, 10, 16, 3535-3538 Organic Letters, 10, 16, 3535-3538 2008/08 Refereed English Disclose to all
S. Ueda; M. Kato; S. Inuki; H. Ohno; B. Evans; Z.-x. Wang; S.C. Peiper; K. Izumi; E. Kodama; M. Matsuoka; H. Nagasawa; S. Oishi; N. Fujii Ueda S, Kato M, Inuki S, Ohno H, Evans B, Wang ZX, Peiper SC, Izumi K, Kodama E, Matsuoka M, Nagasawa H, Oishi S, Fujii N S. Ueda; M. Kato; S. Inuki; H. Ohno; B. Evans; Z.-x. Wang; S.C. Peiper; K. Izumi; E. Kodama; M. Matsuoka; H. Nagasawa; S. Oishi; N. Fujii Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach. Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach Bioorganic and Medicinal Chemistry Letters, 18, 14, 4124-4129 Bioorganic & medicinal chemistry letters, 18, 14, 4124-4129 Bioorganic and Medicinal Chemistry Letters, 18, 14, 4124-4129 2008/07 Refereed English Disclose to all
Y. Yano; A. Yano; S. Oishi; Y. Sugimoto; G. Tsujimoto; N. Fujii; K. Matsuzaki Yano Y, Yano A, Oishi S, Sugimoto Y, Tsujimoto G, Fujii N, Matsuzaki K Y. Yano; A. Yano; S. Oishi; Y. Sugimoto; G. Tsujimoto; N. Fujii; K. Matsuzaki Coiled-coil tag - Probe system for quick labeling of membrane receptors in living cells Coiled-coil tag--probe system for quick labeling of membrane receptors in living cell. Coiled-coil tag - Probe system for quick labeling of membrane receptors in living cells ACS Chemical Biology, 3, 6, 341-345 ACS chemical biology, 3, 6, 341-345 ACS Chemical Biology, 3, 6, 341-345 2008/06 Refereed English Disclose to all
E. Inokuchi; T. Narumi; A. Niida; K. Kobayashi; K. Tomita; S. Oishi; H. Ohno; N. Fujii Inokuchi E, Narumi T, Niida A, Kobayashi K, Tomita K, Oishi S, Ohno H, Fujii N E. Inokuchi; T. Narumi; A. Niida; K. Kobayashi; K. Tomita; S. Oishi; H. Ohno; N. Fujii Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates. Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates Journal of Organic Chemistry, 73, 10, 3942-3945 The Journal of organic chemistry, 73, 10, 3942-3945 Journal of Organic Chemistry, 73, 10, 3942-3945 2008/05 Refereed English Disclose to all
S. Oishi; R. Masuda; B. Evans; S. Ueda; Y. Goto; H. Ohno; A. Hirasawa; G. Tsujimoto; Z. Wang; S.C. Peiper; T. Naito; E. Kodama; M. Matsuoka; N. Fujii Oishi S, Masuda R, Evans B, Ueda S, Goto Y, Ohno H, Hirasawa A, Tsujimoto G, Wang Z, Peiper SC, Naito T, Kodama E, Matsuoka M, Fujii N S. Oishi; R. Masuda; B. Evans; S. Ueda; Y. Goto; H. Ohno; A. Hirasawa; G. Tsujimoto; Z. Wang; S.C. Peiper; T. Naito; E. Kodama; M. Matsuoka; N. Fujii Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4 Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4. Synthesis and application of fluorescein- and biotin-labeled molecular probes for the chemokine receptor CXCR4 ChemBioChem, 9, 7, 1154-1158 Chembiochem : a European journal of chemical biology, 9, 7, 1154-1158 ChemBioChem, 9, 7, 1154-1158 2008/05 Refereed English Disclose to all
T. Watanabe; S. Oishi; N. Fujii; H. Ohno Watanabe T, Oishi S, Fujii N, Ohno H T. Watanabe; S. Oishi; N. Fujii; H. Ohno Palladium-catalyzed sp<sup>3</sup> C-H activation of simple alkyl groups: Direct preparation of indoline derivatives from N-alkyl-2-bromoanilines Palladium-catalyzed sp(3) CH activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines. Palladium-catalyzed sp<sup>3</sup> C-H activation of simple alkyl groups: Direct preparation of indoline derivatives from N-alkyl-2-bromoanilines Organic Letters, 10, 9, 1759-1762 Organic letters, 10, 9, 1759-1762 Organic Letters, 10, 9, 1759-1762 2008/05 Refereed English Disclose to all
Y. Ohta; S. Oishi; N. Fujii; H. Ohno Ohta Y, Oishi S, Fujii N, Ohno H Y. Ohta; S. Oishi; N. Fujii; H. Ohno Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation. Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation Chemical Communications, 7, 835-837 Chemical communications (Cambridge, England), 7, 835-837 Chemical Communications, 7, 835-837 2008/02 Refereed English Disclose to all
S. Oishi; S. Ito; H. Nishikawa; K. Watanabe; M. Tanaka; H. Ohno; K. Izumi; Y. Sakagami; E. Kodama; M. Matsuoka; N. Fujii Oishi S, Ito S, Nishikawa H, Watanabe K, Tanaka M, Ohno H, Izumi K, Sakagami Y, Kodama E, Matsuoka M, Fujii N S. Oishi; S. Ito; H. Nishikawa; K. Watanabe; M. Tanaka; H. Ohno; K. Izumi; Y. Sakagami; E. Kodama; M. Matsuoka; N. Fujii Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity. Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity Journal of Medicinal Chemistry, 51, 3, 388-391 Journal of medicinal chemistry, 51, 3, 388-391 Journal of Medicinal Chemistry, 51, 3, 388-391 2008/02 Refereed English Disclose to all
T. Narumi; K. Tomita; E. Inokuchi; K. Kobayashi; S. Oishi; H. Ohno; N. Fujii Narumi Tetsuo, Tomita Kenji, Inokuchi Eriko, Kobayashi Kazuya, Oishi Shinya, Ohno Hiroaki, Fujii Nobutaka T. Narumi; K. Tomita; E. Inokuchi; K. Kobayashi; S. Oishi; H. Ohno; N. Fujii Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic Tetrahedron, 64, 19, 4332-4346 Tetrahedron, 64, 19, 4332-4346 Tetrahedron, 64, 19, 4332-4346 2008 Refereed English Disclose to all
Katagiri Fumihiko, Nagai Kazuyuki, Tomita Kenji, Kida Atsushi, Oishi Shinya, Itoh Hiroki, Doi Ryuichiro, Fujii Nobutaka, Takeyama Masaharu Katagiri Fumihiko, Nagai Kazuyuki, Tomita Kenji, Kida Atsushi, Oishi Shinya, Itoh Hiroki, Doi Ryuichiro, Fujii Nobutaka, Takeyama Masaharu Katagiri Fumihiko, Nagai Kazuyuki, Tomita Kenji, Kida Atsushi, Oishi Shinya, Itoh Hiroki, Doi Ryuichiro, Fujii Nobutaka, Takeyama Masaharu Utility of plasma bioactive peptides levels as biomarkers Utility of plasma bioactive peptides levels as biomarkers Utility of plasma bioactive peptides levels as biomarkers Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 128, 91 Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 128, 91 Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 128, 91 2008 Refereed Disclose to all
Oishi Shinya, Narumi Tetsuo, Ohno Hiroaki, Otaka Akira, Fujii Nobutaka S. Oishi; T. Narumi; H. Ohno; A. Otaka; N. Fujii Oishi Shinya, Narumi Tetsuo, Ohno Hiroaki, Otaka Akira, Fujii Nobutaka Synthesis of highly functionalized alkene dipeptide isosteres and its application to the structure - Activity relationship study on bioactive peptides Synthesis of highly functionalized alkene dipeptide isosteres and its application to the structure-activity relationship study on bioactive peptides Synthesis of highly functionalized alkene dipeptide isosteres and its application to the structure - Activity relationship study on bioactive peptides Journal of Synthetic Organic Chemistry Japan, 66, 9, 846-857 Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 66, 9, 846-857 Journal of Synthetic Organic Chemistry Japan, 66, 9, 846-857 2008 Refereed Japanese Disclose to all
K. Tomita; S. Oishi; H. Ohno; N. Fujii Tomita K, Oishi S, Ohno H, Fujii N K. Tomita; S. Oishi; H. Ohno; N. Fujii Structure-activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists Structure-activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists. Structure-activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists Biopolymers - Peptide Science Section, 90, 4, 503-511 Biopolymers, 90, 4, 503-511 Biopolymers - Peptide Science Section, 90, 4, 503-511 2008 Refereed English Disclose to all
T. Watanabe; S. Ueda; S. Inuki; S. Oishi; N. Fujii; H. Ohno Watanabe T, Ueda S, Inuki S, Oishi S, Fujii N, Ohno H T. Watanabe; S. Ueda; S. Inuki; S. Oishi; N. Fujii; H. Ohno One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling. One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling Chemical Communications, 43, 4516-4518 Chemical communications (Cambridge, England), 43, 4516-4518 Chemical Communications, 43, 4516-4518 2007/11 Refereed English Disclose to all
T. Watanabe; S. Oishi; N. Fujii; H. Ohno Watanabe T, Oishi S, Fujii N, Ohno H T. Watanabe; S. Oishi; N. Fujii; H. Ohno Gold-catalyzed hydroarylation of allenes: A highly regioselective carbon-carbon bond formation producing six-membered rings Gold-catalyzed hydroarylation of allenes: a highly regioselective carbon-carbon bond formation producing six-membered rings. Gold-catalyzed hydroarylation of allenes: A highly regioselective carbon-carbon bond formation producing six-membered rings Organic Letters, 9, 23, 4821-4824 Organic letters, 9, 23, 4821-4824 Organic Letters, 9, 23, 4821-4824 2007/11 Refereed English Disclose to all
Oishi S, Fujii N Oishi S, Fujii N Oishi S, Fujii N [Peptide-lead drug discovery]. [Peptide-lead drug discovery]. [Peptide-lead drug discovery]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 52, 13 Suppl, 1696-1701 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 52, 13 Suppl, 1696-1701 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 52, 13 Suppl, 1696-1701 2007/10 Refereed Disclose to all
T. Narumi; K. Tomita; E. Inokuchi; K. Kobayashi; S. Oishi; H. Ohno; N. Fujii Narumi T, Tomita K, Inokuchi E, Kobayashi K, Oishi S, Ohno H, Fujii N T. Narumi; K. Tomita; E. Inokuchi; K. Kobayashi; S. Oishi; H. Ohno; N. Fujii Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides. Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides Organic Letters, 9, 17, 3465-3468 Organic letters, 9, 17, 3465-3468 Organic Letters, 9, 17, 3465-3468 2007/08 Refereed English Disclose to all
K. Tomita; S. Oishi; J. Cluzeau; H. Ohno; J.-M. Navenot; Z.-X. Wang; S.C. Peiper; M. Akamatsu; N. Fujii Tomita K, Oishi S, Cluzeau J, Ohno H, Navenot JM, Wang ZX, Peiper SC, Akamatsu M, Fujii N K. Tomita; S. Oishi; J. Cluzeau; H. Ohno; J.-M. Navenot; Z.-X. Wang; S.C. Peiper; M. Akamatsu; N. Fujii SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54 SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54. SAR and QSAR studies on the N-terminally acylated pentapeptide agonists for GPR54 Journal of Medicinal Chemistry, 50, 14, 3222-3228 Journal of medicinal chemistry, 50, 14, 3222-3228 Journal of Medicinal Chemistry, 50, 14, 3222-3228 2007/07 Refereed English Disclose to all
N. Ogo; S. Oishi; K. Matsuno; J.-i. Sawada; N. Fujii; A. Asai Ogo N, Oishi S, Matsuno K, Sawada J, Fujii N, Asai A N. Ogo; S. Oishi; K. Matsuno; J.-i. Sawada; N. Fujii; A. Asai Synthesis and biological evaluation of l-cysteine derivatives as mitotic kinesin Eg5 inhibitors Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors. Synthesis and biological evaluation of l-cysteine derivatives as mitotic kinesin Eg5 inhibitors Bioorganic and Medicinal Chemistry Letters, 17, 14, 3921-3924 Bioorganic & medicinal chemistry letters, 17, 14, 3921-3924 Bioorganic and Medicinal Chemistry Letters, 17, 14, 3921-3924 2007/07 Refereed English Disclose to all
J. Cluzeau; S. Oishi; H. Ohno; Z. Wang; B. Evans; S.C. Peiper; N. Fujii Cluzeau J, Oishi S, Ohno H, Wang Z, Evans B, Peiper SC, Fujii N J. Cluzeau; S. Oishi; H. Ohno; Z. Wang; B. Evans; S.C. Peiper; N. Fujii Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists. Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists Organic and Biomolecular Chemistry, 5, 12, 1915-1923 Organic & biomolecular chemistry, 5, 12, 1915-1923 Organic and Biomolecular Chemistry, 5, 12, 1915-1923 2007/06 Refereed English Disclose to all
F. Katagiri; K. Tomita; S. Oishi; M. Takeyama; N. Fujii Katagiri F, Tomita K, Oishi S, Takeyama M, Fujii N F. Katagiri; K. Tomita; S. Oishi; M. Takeyama; N. Fujii Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin. Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin Journal of Peptide Science, 13, 6, 422-429 Journal of peptide science : an official publication of the European Peptide Society, 13, 6, 422-429 Journal of Peptide Science, 13, 6, 422-429 2007/06 Refereed English Disclose to all
S.-U. Kang; J.C. Won; S. Oishi; K. Lee; R.G. Karki; K.M. Worthy; L.K. Bindu; M.C. Nicklaus; R.J. Fisher; T.R. Burke Jr. Kang SU, Choi WJ, Oishi S, Lee K, Karki RG, Worthy KM, Bindu LK, Nicklaus MC, Fisher RJ, Burke TR Jr S.-U. Kang; J.C. Won; S. Oishi; K. Lee; R.G. Karki; K.M. Worthy; L.K. Bindu; M.C. Nicklaus; R.J. Fisher; T.R. Burke Jr. Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides. Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides Journal of Medicinal Chemistry, 50, 8, 1978-1982 Journal of medicinal chemistry, 50, 8, 1978-1982 Journal of Medicinal Chemistry, 50, 8, 1978-1982 2007/04 Refereed English Disclose to all
K. Kato-Takagaki; N. Suzuki; F. Yokoyama; S. Takaki; K. Umezawa; J. Higo; M. Mochizuki; Y. Kikkawa; S. Oishi; A. Utani; M. Nomizu Kato-Takagaki K, Suzuki N, Yokoyama F, Takaki S, Umezawa K, Higo J, Mochizuki M, Kikkawa Y, Oishi S, Utani A, Nomizu M K. Kato-Takagaki; N. Suzuki; F. Yokoyama; S. Takaki; K. Umezawa; J. Higo; M. Mochizuki; Y. Kikkawa; S. Oishi; A. Utani; M. Nomizu Cyclic peptide analysis of the biologically active loop region in the laminin α3 chain LG4 module demonstrates the importance of peptide conformation on biological activity Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. Cyclic peptide analysis of the biologically active loop region in the laminin α3 chain LG4 module demonstrates the importance of peptide conformation on biological activity Biochemistry, 46, 7, 1952-1960 Biochemistry, 46, 7, 1952-1960 Biochemistry, 46, 7, 1952-1960 2007/02 Refereed English Disclose to all
S. Ueda; S. Oishi; Z.-X. Wang; T. Araki; H. Tamamura; J. Cluzeau; H. Ohno; S. Kusano; H. Nakashima; J.O. Trent; S.C. Peiper; N. Fujii Ueda S, Oishi S, Wang ZX, Araki T, Tamamura H, Cluzeau J, Ohno H, Kusano S, Nakashima H, Trent JO, Peiper SC, Fujii N S. Ueda; S. Oishi; Z.-X. Wang; T. Araki; H. Tamamura; J. Cluzeau; H. Ohno; S. Kusano; H. Nakashima; J.O. Trent; S.C. Peiper; N. Fujii Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: Disclosing the importance of side-chain and backbone functionalities Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities. Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: Disclosing the importance of side-chain and backbone functionalities Journal of Medicinal Chemistry, 50, 2, 192-198 Journal of medicinal chemistry, 50, 2, 192-198 Journal of Medicinal Chemistry, 50, 2, 192-198 2007/01 Refereed English Disclose to all
M. Tanaka; S. Oishi; H. Ohno; N. Fujii Tanaka Michinori, Oishi Shinya, Ohno Hiroaki, Fujii Nobutaka M. Tanaka; S. Oishi; H. Ohno; N. Fujii A novel oxazolidine linker for the synthesis of peptide aldehydes A novel oxazolidine linker for the synthesis of peptide aldehydes A novel oxazolidine linker for the synthesis of peptide aldehydes International Journal of Peptide Research and Therapeutics, 13, 1-2, 271-279 International Journal of Peptide Research and Therapeutics, 13, 1-2, 271-279 International Journal of Peptide Research and Therapeutics, 13, 1-2, 271-279 2007 Refereed English Disclose to all
H. Tamamura; T. Tanaka; H. Tsutsumi; K. Nemoto; S. Mizokami; N. Ohashi; S. Oishi; N. Fujii Tamamura Hirokazu, Tanaka Tomohiro, Tsutsumi Hiroshi, Nemoto Koji, Mizokami Satoko, Ohashi Nami, Oishi Shinya, Fujii Nobutaka H. Tamamura; T. Tanaka; H. Tsutsumi; K. Nemoto; S. Mizokami; N. Ohashi; S. Oishi; N. Fujii Versatile use of acid-catalyzed ring-opening of β-aziridinyl-α,β-enoates to stereoselective synthesis of peptidomimetics Versatile use of acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates to stereoselective synthesis of peptidomimetics Versatile use of acid-catalyzed ring-opening of β-aziridinyl-α,β-enoates to stereoselective synthesis of peptidomimetics Tetrahedron, 63, 37, 9243-9254 Tetrahedron, 63, 37, 9243-9254 Tetrahedron, 63, 37, 9243-9254 2007 Refereed English Disclose to all
H. Ohno; Y. Ohta; S. Oishi; N. Fujii Ohno H, Ohta Y, Oishi S, Fujii N H. Ohno; Y. Ohta; S. Oishi; N. Fujii Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions. Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions Angewandte Chemie - International Edition, 46, 13, 2295-2298 Angewandte Chemie (International ed. in English), 46, 13, 2295-2298 Angewandte Chemie - International Edition, 46, 13, 2295-2298 2007 Refereed English Disclose to all
K. Tomita; T. Narumi; A. Niida; S. Oishi; H. Ohno; N. Fujii Tomita K, Narumi T, Niida A, Oishi S, Ohno H, Fujii N K. Tomita; T. Narumi; A. Niida; S. Oishi; H. Ohno; N. Fujii Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres. Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres Biopolymers - Peptide Science Section, 88, 2, 272-278 Biopolymers, 88, 2, 272-278 Biopolymers - Peptide Science Section, 88, 2, 272-278 2007 Refereed English Disclose to all
H. Tsutsumi; T. Tanaka; N. Ohashi; H. Masuno; H. Tamamura; K. Hiramatsu; T. Araki; S. Ueda; S. Oishi; N. Fujii Tsutsumi H, Tanaka T, Ohashi N, Masuno H, Tamamura H, Hiramatsu K, Araki T, Ueda S, Oishi S, Fujii N H. Tsutsumi; T. Tanaka; N. Ohashi; H. Masuno; H. Tamamura; K. Hiramatsu; T. Araki; S. Ueda; S. Oishi; N. Fujii Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents. Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents Biopolymers - Peptide Science Section, 88, 2, 279-289 Biopolymers, 88, 2, 279-289 Biopolymers - Peptide Science Section, 88, 2, 279-289 2007 Refereed English Disclose to all
T. Narumi; A. Niida; K. Tomita; S. Oishi; A. Otaka; H. Ohno; N. Fujii Narumi T, Niida A, Tomita K, Oishi S, Otaka A, Ohno H, Fujii N T. Narumi; A. Niida; K. Tomita; S. Oishi; A. Otaka; H. Ohno; N. Fujii A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres. A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres Chemical Communications, 45, 4720-4722 Chemical communications (Cambridge, England), 45, 4720-4722 Chemical Communications, 45, 4720-4722 2006/12 Refereed English Disclose to all
K. Tomita; A. Niida; S. Oishi; H. Ohno; J. Cluzeau; J.-M. Navenot; Z.-x. Wang; S.C. Peiper; N. Fujii Tomita K, Niida A, Oishi S, Ohno H, Cluzeau J, Navenot JM, Wang ZX, Peiper SC, Fujii N K. Tomita; A. Niida; S. Oishi; H. Ohno; J. Cluzeau; J.-M. Navenot; Z.-x. Wang; S.C. Peiper; N. Fujii Structure-activity relationship study on small peptidic GPR54 agonists Structure-activity relationship study on small peptidic GPR54 agonists. Structure-activity relationship study on small peptidic GPR54 agonists Bioorganic and Medicinal Chemistry, 14, 22, 7595-7603 Bioorganic & medicinal chemistry, 14, 22, 7595-7603 Bioorganic and Medicinal Chemistry, 14, 22, 7595-7603 2006/11 Refereed English Disclose to all
A. Niida; M. Mizumoto; T. Narumi; E. Inokuchi; S. Oishi; H. Ohno; A. Otaka; K. Kitaura; N. Fujii Niida A, Mizumoto M, Narumi T, Inokuchi E, Oishi S, Ohno H, Otaka A, Kitaura K, Fujii N A. Niida; M. Mizumoto; T. Narumi; E. Inokuchi; S. Oishi; H. Ohno; A. Otaka; K. Kitaura; N. Fujii Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations. Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations Journal of Organic Chemistry, 71, 11, 4118-4129 The Journal of organic chemistry, 71, 11, 4118-4129 Journal of Organic Chemistry, 71, 11, 4118-4129 2006/05 Refereed English Disclose to all
A. Niida; H. Tanigaki; E. Inokuchi; Y. Sasaki; S. Oishi; H. Ohno; H. Tamamura; Z. Wang; S.C. Peiper; K. Kitaura; A. Otaka; N. Fujii Niida A, Tanigaki H, Inokuchi E, Sasaki Y, Oishi S, Ohno H, Tamamura H, Wang Z, Peiper SC, Kitaura K, Otaka A, Fujii N A. Niida; H. Tanigaki; E. Inokuchi; Y. Sasaki; S. Oishi; H. Ohno; H. Tamamura; Z. Wang; S.C. Peiper; K. Kitaura; A. Otaka; N. Fujii Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-S <sub>N</sub>2′ reactions and their use in the preparation of low-molecule CXCR4 antagonists Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists. Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-S <sub>N</sub>2′ reactions and their use in the preparation of low-molecule CXCR4 antagonists Journal of Organic Chemistry, 71, 10, 3942-3951 The Journal of organic chemistry, 71, 10, 3942-3951 Journal of Organic Chemistry, 71, 10, 3942-3951 2006/05 Refereed English Disclose to all
A. Niida; K. Tomita; M. Mizumoto; H. Tanigaki; T. Terada; S. Oishi; A. Otaka; K.-I. Inui; N. Fujii Niida A, Tomita K, Mizumoto M, Tanigaki H, Terada T, Oishi S, Otaka A, Inui K, Fujii N A. Niida; K. Tomita; M. Mizumoto; H. Tanigaki; T. Terada; S. Oishi; A. Otaka; K.-I. Inui; N. Fujii Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1 Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1. Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1 Organic Letters, 8, 4, 613-616 Organic letters, 8, 4, 613-616 Organic Letters, 8, 4, 613-616 2006/02 Refereed English Disclose to all
A. Niida; Z. Wang; K. Tomita; S. Oishi; H. Tamamura; A. Otaka; J.-M. Navenot; J.R. Broach; S.C. Peiper; N. Fujii Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N A. Niida; Z. Wang; K. Tomita; S. Oishi; H. Tamamura; A. Otaka; J.-M. Navenot; J.R. Broach; S.C. Peiper; N. Fujii Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity Bioorganic and Medicinal Chemistry Letters, 16, 1, 134-137 Bioorganic & medicinal chemistry letters, 16, 1, 134-137 Bioorganic and Medicinal Chemistry Letters, 16, 1, 134-137 2006/01 Refereed English Disclose to all
S. Oishi; K. Miyamoto; A. Niida; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; Y. Kuroda; A. Asai; N. Fujii Oishi S, Miyamoto K, Niida A, Yamamoto M, Ajito K, Tamamura H, Otaka A, Kuroda Y, Asai A, Fujii N S. Oishi; K. Miyamoto; A. Niida; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; Y. Kuroda; A. Asai; N. Fujii Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides Tetrahedron, 62, 7, 1416-1424 Tetrahedron, 62, 7, 1416-1424 Tetrahedron, 62, 7, 1416-1424 2006 Refereed English Disclose to all
H. Tamamura; T. Araki; S. Ueda; Z. Wang; S. Oishi; A. Esaka; J.O. Trent; H. Nakashima; N. Yamamoto; S.C. Peiper; A. Otaka; N. Fujii Tamamura H, Araki T, Ueda S, Wang Z, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N H. Tamamura; T. Araki; S. Ueda; Z. Wang; S. Oishi; A. Esaka; J.O. Trent; H. Nakashima; N. Yamamoto; S.C. Peiper; A. Otaka; N. Fujii Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds. Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds Journal of Medicinal Chemistry, 48, 9, 3280-3289 Journal of medicinal chemistry, 48, 9, 3280-3289 Journal of Medicinal Chemistry, 48, 9, 3280-3289 2005/05 Refereed English Disclose to all
N. Ichikawa; S. Kasai; N. Suzuki; N. Nishi; S. Oishi; N. Fujii; Y. Kadoya; K. Hatori; Y. Mizuno; M. Nomizu; E. Arikawa-Hirasawa Ichikawa N, Kasai S, Suzuki N, Nishi N, Oishi S, Fujii N, Kadoya Y, Hatori K, Mizuno Y, Nomizu M, Arikawa-Hirasawa E N. Ichikawa; S. Kasai; N. Suzuki; N. Nishi; S. Oishi; N. Fujii; Y. Kadoya; K. Hatori; Y. Mizuno; M. Nomizu; E. Arikawa-Hirasawa Identification of neurite outgrowth active sites on the laminin α4 chain G domain Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. Identification of neurite outgrowth active sites on the laminin α4 chain G domain Biochemistry, 44, 15, 5755-5762 Biochemistry, 44, 15, 5755-5762 Biochemistry, 44, 15, 5755-5762 2005/04 Refereed English Disclose to all
S. Oishi; R.G. Karki; Z.-D. Shi; K.M. Worthy; L. Bindu; O. Chertov; D. Esposito; P. Frank; W.K. Gillette; M. Maderia; J. Hartley; M.C. Nicklaus; J.J. Barchi Jr.; R.J. Fisher; T.R. Burke Jr. Oishi S, Karki RG, Shi ZD, Worthy KM, Bindu L, Chertov O, Esposito D, Frank P, Gillette WK, Maderia M, Hartley J, Nicklaus MC, Barchi JJ Jr, Fisher RJ, Burke TR Jr S. Oishi; R.G. Karki; Z.-D. Shi; K.M. Worthy; L. Bindu; O. Chertov; D. Esposito; P. Frank; W.K. Gillette; M. Maderia; J. Hartley; M.C. Nicklaus; J.J. Barchi Jr.; R.J. Fisher; T.R. Burke Jr. Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic. Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic Bioorganic and Medicinal Chemistry, 13, 7, 2431-2438 Bioorganic & medicinal chemistry, 13, 7, 2431-2438 Bioorganic and Medicinal Chemistry, 13, 7, 2431-2438 2005/04 Refereed English Disclose to all
S. Oishi; Z.-D. Shi; K.M. Worthy; L.K. Bindu; R.J. Fisher; T.R. Burke Oishi S, Shi ZD, Worthy KM, Bindu LK, Fisher RJ, Burke TR Jr S. Oishi; Z.-D. Shi; K.M. Worthy; L.K. Bindu; R.J. Fisher; T.R. Burke Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocyles Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles. Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocyles ChemBioChem, 6, 4, 668-674 Chembiochem : a European journal of chemical biology, 6, 4, 668-674 ChemBioChem, 6, 4, 668-674 2005/04 Refereed English Disclose to all
Z.-D. Shi; R.G. Karki; S. Oishi; K.M. Worthy; L.K. Bindu; P.G. Dharmawardana; M.C. Nicklaus; D.P. Bottaro; R.J. Fisher; T.R. Burke Jr. Shi ZD, Karki RG, Oishi S, Worthy KM, Bindu LK, Dharmawardana PG, Nicklaus MC, Bottaro DP, Fisher RJ, Burke TR Jr Z.-D. Shi; R.G. Karki; S. Oishi; K.M. Worthy; L.K. Bindu; P.G. Dharmawardana; M.C. Nicklaus; D.P. Bottaro; R.J. Fisher; T.R. Burke Jr. Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic. Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic Bioorganic and Medicinal Chemistry Letters, 15, 5, 1385-1388 Bioorganic & medicinal chemistry letters, 15, 5, 1385-1388 Bioorganic and Medicinal Chemistry Letters, 15, 5, 1385-1388 2005/03 Refereed English Disclose to all
S. Oishi; R.G. Karki; S.-U. Kang; X. Wang; K.M. Worthy; L.K. Bindu; M.C. Nicklaus; R.J. Fisher; T.R. Burke Jr. Oishi S, Karki RG, Kang SU, Wang X, Worthy KM, Bindu LK, Nicklaus MC, Fisher RJ, Burke TR Jr S. Oishi; R.G. Karki; S.-U. Kang; X. Wang; K.M. Worthy; L.K. Bindu; M.C. Nicklaus; R.J. Fisher; T.R. Burke Jr. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing α-methylphenylalanyl based phosphotyrosyl mimetics Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing α-methylphenylalanyl based phosphotyrosyl mimetics Journal of Medicinal Chemistry, 48, 3, 764-772 Journal of medicinal chemistry, 48, 3, 764-772 Journal of Medicinal Chemistry, 48, 3, 764-772 2005/02 Refereed English Disclose to all
A. Niida; S. Oishi; Y. Sasaki; M. Mizumoto; H. Tamamura; N. Fujii; A. Otaka Niida A, Oishi S, Sasaki Y, Mizumoto M, Tamamura H, Fujii N, Otaka A A. Niida; S. Oishi; Y. Sasaki; M. Mizumoto; H. Tamamura; N. Fujii; A. Otaka Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-S<sub>N</sub>2′ reactions Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-S(N)2 ' reactions Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-S<sub>N</sub>2′ reactions Tetrahedron Letters, 46, 24, 4183-4186 Tetrahedron Letters, 46, 24, 4183-4186 Tetrahedron Letters, 46, 24, 4183-4186 2005 Refereed English Disclose to all
Niida A, Oishi S, Mizumoto M, Sasaki Y, Tomita K, Tamamura H, Otaka A, Terada T, Inui K, Fujii N Niida A, Oishi S, Mizumoto M, Sasaki Y, Tomita K, Tamamura H, Otaka A, Terada T, Inui K, Fujii N Niida A, Oishi S, Mizumoto M, Sasaki Y, Tomita K, Tamamura H, Otaka A, Terada T, Inui K, Fujii N Unequivocal synthesis of (Z)-alkene or (E)-fluoroalkene dipeptide isosteres via DKP mimetics to probe structural requirements of peptide transporter Unequivocal synthesis of (Z)-alkene or (E)-fluoroalkene dipeptide isosteres via DKP mimetics to probe structural requirements of peptide transporter Unequivocal synthesis of (Z)-alkene or (E)-fluoroalkene dipeptide isosteres via DKP mimetics to probe structural requirements of peptide transporter Biopolymers, 80, 4, 513 Biopolymers, 80, 4, 513 Biopolymers, 80, 4, 513 2005 Refereed Disclose to all
F. Yokoyama; N. Suzuki; M. Haruki; N. Nishi; S. Oishi; N. Fujii; A. Utani; H.K. Kleinman; M. Nomizu Yokoyama F, Suzuki N, Haruki M, Nishi N, Oishi S, Fujii N, Utani A, Kleinman HK, Nomizu M F. Yokoyama; N. Suzuki; M. Haruki; N. Nishi; S. Oishi; N. Fujii; A. Utani; H.K. Kleinman; M. Nomizu Cyclic peptides from the loop region of the laminin α4 chain LG4 module show enhanced biological activity over linear peptides Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides. Cyclic peptides from the loop region of the laminin α4 chain LG4 module show enhanced biological activity over linear peptides Biochemistry, 43, 42, 13590-13597 Biochemistry, 43, 42, 13590-13597 Biochemistry, 43, 42, 13590-13597 2004/10 Refereed English Disclose to all
S. Oishi Oishi S S. Oishi Structure-activity relationship studies on cyclic RGD peptides utilizing novel alkene dipeptide isosteres Structure-activity relationship studies on cyclic RGD peptides utilizing novel alkene dipeptide isosteres. Structure-activity relationship studies on cyclic RGD peptides utilizing novel alkene dipeptide isosteres Yakugaku Zasshi, 124, 5, 269-277 Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 124, 5, 269-277 Yakugaku Zasshi, 124, 5, 269-277 2004/05 Refereed English Disclose to all
A. Otaka; J. Watanabe; A. Yukimasa; Y. Sasaki; H. Watanabe; T. Kinoshita; S. Oishi; H. Tamamura; N. Fujii Otaka A, Watanabe J, Yukimasa A, Sasaki Y, Watanabe H, Kinoshita T, Oishi S, Tamamura H, Fujii N A. Otaka; J. Watanabe; A. Yukimasa; Y. Sasaki; H. Watanabe; T. Kinoshita; S. Oishi; H. Tamamura; N. Fujii SmI<sub>2</sub>-Mediated Reduction of γ,γ-Difluoro-α ,β-enoates with Application to the Synthesis of Functionalized (Z)-Fluoroalkene-Type Dipeptide Isosteres SmI2-mediated reduction of gamma,gamma-difluoro-alpha,beta-enoates with application to the synthesis of functionalized (Z)-fluoroalkene-type dipeptide isosteres. SmI<sub>2</sub>-Mediated Reduction of γ,γ-Difluoro-α ,β-enoates with Application to the Synthesis of Functionalized (Z)-Fluoroalkene-Type Dipeptide Isosteres Journal of Organic Chemistry, 69, 5, 1634-1645 The Journal of organic chemistry, 69, 5, 1634-1645 Journal of Organic Chemistry, 69, 5, 1634-1645 2004/03 Refereed English Disclose to all
T. Masui; R. Doi; T. Mori; E. Toyoda; M. Koizumi; K. Kami; D. Ito; S.C. Peiper; J.R. Broach; S. Oishi; A. Niida; N. Fujii; M. Imamura Masui T, Doi R, Mori T, Toyoda E, Koizumi M, Kami K, Ito D, Peiper SC, Broach JR, Oishi S, Niida A, Fujii N, Imamura M T. Masui; R. Doi; T. Mori; E. Toyoda; M. Koizumi; K. Kami; D. Ito; S.C. Peiper; J.R. Broach; S. Oishi; A. Niida; N. Fujii; M. Imamura Metastin and its variant forms suppress migration of pancreatic cancer cells Metastin and its variant forms suppress migration of pancreatic cancer cells. Metastin and its variant forms suppress migration of pancreatic cancer cells Biochemical and Biophysical Research Communications, 315, 1, 85-92 Biochemical and biophysical research communications, 315, 1, 85-92 Biochemical and Biophysical Research Communications, 315, 1, 85-92 2004/02 Refereed English Disclose to all
Tamamura H, Hiramatsu K, Araki T, Mizokami S, Oishi S, Ueda S, Wang Z, Peiper S. C, Trent J. O, Hori A, Kanzaki N, Fujiwara M, Nakashima H, Yamamoto N, Otaka A, Fujii N. Tamamura H, Hiramatsu K, Araki T, Mizokami S, Oishi S, Ueda S, Wang Z, Peiper S. C, Trent J. O, Hori A, Kanzaki N, Fujiwara M, Nakashima H, Yamamoto N, Otaka A, Fujii N. Tamamura H, Hiramatsu K, Araki T, Mizokami S, Oishi S, Ueda S, Wang Z, Peiper S. C, Trent J. O, Hori A, Kanzaki N, Fujiwara M, Nakashima H, Yamamoto N, Otaka A, Fujii N. LOW MOLECULAR WEIGHT CXCR4 ANTAGONISTS BASED ON T140 ANALOGS THAT WERE IDENTIFIED AS TRIPLE-FUNCTIONAL AGENTS HAVING INHIBITORY ACTIVITIES AGAINST HIV INFECTION, CANCER METASTASIS AND RHEUMATOID ARTHRITIS LOW MOLECULAR WEIGHT CXCR4 ANTAGONISTS BASED ON T140 ANALOGS THAT WERE IDENTIFIED AS TRIPLE-FUNCTIONAL AGENTS HAVING INHIBITORY ACTIVITIES AGAINST HIV INFECTION, CANCER METASTASIS AND RHEUMATOID ARTHRITIS LOW MOLECULAR WEIGHT CXCR4 ANTAGONISTS BASED ON T140 ANALOGS THAT WERE IDENTIFIED AS TRIPLE-FUNCTIONAL AGENTS HAVING INHIBITORY ACTIVITIES AGAINST HIV INFECTION, CANCER METASTASIS AND RHEUMATOID ARTHRITIS Journal of Peptide Science, 10, 115 Journal of Peptide Science, 10, 115 Journal of Peptide Science, 10, 115 2004 Refereed Disclose to all
S. Oishi; S.-U. Kang; H. Liu; M. Zhang; D. Yang; J.R. Deschamps; T.R. Burke Jr. Oishi S, Kang SU, Liu HP, Zhang MC, Yang DJ, Deschamps JR, Burke TR S. Oishi; S.-U. Kang; H. Liu; M. Zhang; D. Yang; J.R. Deschamps; T.R. Burke Jr. Synthesis of α,α-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics Synthesis of alpha,alpha-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics Synthesis of α,α-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics Tetrahedron, 60, 13, 2971-2977 Tetrahedron, 60, 13, 2971-2977 Tetrahedron, 60, 13, 2971-2977 2004 Refereed English Disclose to all
N. Suzuki; H. Nakatsuka; M. Mochizuki; N. Nishi; Y. Kadoya; A. Utani; S. Oishi; N. Fujii; H.K. Kleinman; M. Nomizu Suzuki N, Nakatsuka H, Mochizuki M, Nishi N, Kadoya Y, Utani A, Oishi S, Fujii N, Kleinman HK, Nomizu M N. Suzuki; H. Nakatsuka; M. Mochizuki; N. Nishi; Y. Kadoya; A. Utani; S. Oishi; N. Fujii; H.K. Kleinman; M. Nomizu Biological Activities of Homologous Loop Regions in the Laminin α Chain G Domains Biological activities of homologous loop regions in the laminin alpha chain G domains. Biological Activities of Homologous Loop Regions in the Laminin α Chain G Domains Journal of Biological Chemistry, 278, 46, 45697-45705 The Journal of biological chemistry, 278, 46, 45697-45705 Journal of Biological Chemistry, 278, 46, 45697-45705 2003/11 Refereed English Disclose to all
N. Fujii; S. Oishi; K. Hiramatsu; T. Araki; S. Ueda; H. Tamamura; A. Otaka; S. Kusano; S. Terakubo; H. Nakashima; J.A. Broach; J.O. Trent; Z.-X. Wang; S.C. Peiper Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC N. Fujii; S. Oishi; K. Hiramatsu; T. Araki; S. Ueda; H. Tamamura; A. Otaka; S. Kusano; S. Terakubo; H. Nakashima; J.A. Broach; J.O. Trent; Z.-X. Wang; S.C. Peiper Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries Angewandte Chemie - International Edition, 42, 28, 3251-3253 Angewandte Chemie (International ed. in English), 42, 28, 3251-3253 Angewandte Chemie - International Edition, 42, 28, 3251-3253 2003/07 Refereed English Disclose to all
Ogawa M, Hatano K, Oishi S, Kawasumi Y, Fujii N, Kawaguchi M, Doi R, Imamura M, Yamamoto M, Ajito K, Mukai T, Saji H, Ito K Ogawa M, Hatano K, Oishi S, Kawasumi Y, Fujii N, Kawaguchi M, Doi R, Imamura M, Yamamoto M, Ajito K, Mukai T, Saji H, Ito K Ogawa M, Hatano K, Oishi S, Kawasumi Y, Fujii N, Kawaguchi M, Doi R, Imamura M, Yamamoto M, Ajito K, Mukai T, Saji H, Ito K Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging. Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging. Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging. Nuclear medicine and biology, 30, 1, 1-9 Nuclear medicine and biology, 30, 1, 1-9 Nuclear medicine and biology, 30, 1, 1-9 2003/01 Refereed Disclose to all
Otaka A, Yukimasa A, Watanabe J, Sasaki Y, Oishi S, Tamamura H, Fujii N Otaka A, Yukimasa A, Watanabe J, Sasaki Y, Oishi S, Tamamura H, Fujii N Otaka A, Yukimasa A, Watanabe J, Sasaki Y, Oishi S, Tamamura H, Fujii N Application of samarium diiodide (SmI2)-induced reduction of gamma-acetoxy-alpha,beta-enoates with alpha-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives Application of samarium diiodide (SmI2)-induced reduction of gamma-acetoxy-alpha,beta-enoates with alpha-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives Application of samarium diiodide (SmI2)-induced reduction of gamma-acetoxy-alpha,beta-enoates with alpha-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives Chemical Communications, 15, 1834-1835 Chemical Communications, 15, 1834-1835 Chemical Communications, 15, 1834-1835 2003 Refereed Disclose to all
M. Ogawa; K. Hatano; S. Oishi; Y. Kawasumi; N. Fujii; M. Kawaguchi; R. Doi; M. Imamura; M. Yamamoto; K. Ajito; T. Mukai; H. Saji; K. Ito Ogawa M, Hatano K, Oishi S, Kawasumi Y, Fujii N, Kawaguchi M, Doi R, Imamura M, Yamamoto M, Ajito K, Mukai T, Saji H, Ito K M. Ogawa; K. Hatano; S. Oishi; Y. Kawasumi; N. Fujii; M. Kawaguchi; R. Doi; M. Imamura; M. Yamamoto; K. Ajito; T. Mukai; H. Saji; K. Ito Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo α<sub>v</sub>β<sub>3</sub> integrin related tumor imaging Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta(3) integrin related tumor imaging Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo α<sub>v</sub>β<sub>3</sub> integrin related tumor imaging Nuclear Medicine and Biology, 30, 1, 1-9 Nuclear Medicine and Biology, 30, 1, 1-9 Nuclear Medicine and Biology, 30, 1, 1-9 2003 Refereed English Disclose to all
S. Oishi; T. Kamano; A. Niida; Y. Odagaki; N. Hamanaka; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; N. Fujii Oishi S, Kamano T, Niida A, Odagaki Y, Hamanaka N, Yamamoto M, Ajito K, Tamamura H, Otaka A, Fujii N S. Oishi; T. Kamano; A. Niida; Y. Odagaki; N. Hamanaka; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; N. Fujii Diastereoselective synthesis of new ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics. Diastereoselective synthesis of new ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics Journal of Organic Chemistry, 67, 17, 6162-6173 The Journal of organic chemistry, 67, 17, 6162-6173 Journal of Organic Chemistry, 67, 17, 6162-6173 2002/08 Refereed English Disclose to all
A. Otaka; F. Katagiri; T. Kinoshita; Y. Odagaki; S. Oishi; H. Tamamura; N. Hamanaka; N. Fujii Otaka A, Katagiri F, Kinoshita T, Odagaki Y, Oishi S, Tamamura H, Hamanaka N, Fujii N A. Otaka; F. Katagiri; T. Kinoshita; Y. Odagaki; S. Oishi; H. Tamamura; N. Hamanaka; N. Fujii Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated Anti-S<sub>N</sub>2′ reactions Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated anti-S(N)2' reactions. Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated Anti-S<sub>N</sub>2′ reactions Journal of Organic Chemistry, 67, 17, 6152-6161 The Journal of organic chemistry, 67, 17, 6152-6161 Journal of Organic Chemistry, 67, 17, 6152-6161 2002/08 Refereed English Disclose to all
H. Tamamura; A. Omagari; K. Hiramatsu; S. Oishi; H. Habashita; T. Kanamoto; K. Gotoh; N. Yamamoto; H. Nakashima; A. Otaka; N. Fujii Tamamura H, Omagari A, Hiramatsu K, Oishi S, Habashita H, Kanamoto T, Gotoh K, Yamamoto N, Nakashima H, Otaka A, Fujii N H. Tamamura; A. Omagari; K. Hiramatsu; S. Oishi; H. Habashita; T. Kanamoto; K. Gotoh; N. Yamamoto; H. Nakashima; A. Otaka; N. Fujii Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study. Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study Bioorganic and Medicinal Chemistry, 10, 5, 1417-1426 Bioorganic & medicinal chemistry, 10, 5, 1417-1426 Bioorganic and Medicinal Chemistry, 10, 5, 1417-1426 2002/05 Refereed English Disclose to all
S. Oishi; A. Niida; T. Kamano; Y. Odagaki; H. Tamamura; A. Otaka; N. Hamanaka; N. Fujii Oishi S, Niida A, Kamano T, Odagaki Y, Tamamura H, Otaka A, Hamanaka N, Fujii N S. Oishi; A. Niida; T. Kamano; Y. Odagaki; H. Tamamura; A. Otaka; N. Hamanaka; N. Fujii Diastereoselective Synthesis of ψ[(E)-CMe=CH]- and ψ[(E)-CMe=CMe]-Type Dipeptide Isosteres Based on Organocopper-mediated anti-S<sub>N</sub>2′ Reaction Diastereoselective synthesis of psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]- type dipeptide isosteres based on organocopper-mediated anti-S(N)2' reaction. Diastereoselective Synthesis of ψ[(E)-CMe=CH]- and ψ[(E)-CMe=CMe]-Type Dipeptide Isosteres Based on Organocopper-mediated anti-S<sub>N</sub>2′ Reaction Organic Letters, 4, 7, 1055-1058 Organic letters, 4, 7, 1055-1058 Organic Letters, 4, 7, 1055-1058 2002/04 Refereed English Disclose to all
S. Oishi; T. Kamano; A. Niida; Y. Odagaki; H. Tamamura; A. Otaka; N. Hamanaka; N. Fujii Oishi S, Kamano T, Niida A, Odagaki Y, Tamamura H, Otaka A, Hamanaka N, Fujii N S. Oishi; T. Kamano; A. Niida; Y. Odagaki; H. Tamamura; A. Otaka; N. Hamanaka; N. Fujii Diastereoselective Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-Type Dipeptide Isosteres by Organocopper-mediated anti-S<sub>N</sub>2′ Reaction Diastereoselective synthesis of psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type dipeptide isosteres by organocopper-mediated anti-S(N)2' reaction. Diastereoselective Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-Type Dipeptide Isosteres by Organocopper-mediated anti-S<sub>N</sub>2′ Reaction Organic Letters, 4, 7, 1051-1054 Organic letters, 4, 7, 1051-1054 Organic Letters, 4, 7, 1051-1054 2002/04 Refereed English Disclose to all
H. Tamamura; K. Hiramatsu; K. Miyamoto; A. Omagari; S. Oishi; H. Nakashima; N. Yamamoto; Y. Kuroda; T. Nakagawa; A. Otaka; N. Fujii Tamamura H, Hiramatsu K, Miyamoto K, Omagari A, Oishi S, Nakashima H, Yamamoto N, Kuroda Y, Nakagawa T, Otaka A, Fujii N H. Tamamura; K. Hiramatsu; K. Miyamoto; A. Omagari; S. Oishi; H. Nakashima; N. Yamamoto; Y. Kuroda; T. Nakagawa; A. Otaka; N. Fujii Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: The insertion of an (E)-alkene dipeptide isostere into the βII′-turn moiety Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety. Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: The insertion of an (E)-alkene dipeptide isostere into the βII′-turn moiety Bioorganic and Medicinal Chemistry Letters, 12, 6, 923-928 Bioorganic & medicinal chemistry letters, 12, 6, 923-928 Bioorganic and Medicinal Chemistry Letters, 12, 6, 923-928 2002/03 Refereed English Disclose to all
H. Ohno; K. Miyamura; T. Tanaka; S. Oishi; A. Toda; Y. Takemoto; N. Fujii; T. Ibuka Ohno H, Miyamura K, Tanaka T, Oishi S, Toda A, Takemoto Y, Fujii N, Ibuka T H. Ohno; K. Miyamura; T. Tanaka; S. Oishi; A. Toda; Y. Takemoto; N. Fujii; T. Ibuka Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system. Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system Journal of Organic Chemistry, 67, 4, 1359-1367 The Journal of organic chemistry, 67, 4, 1359-1367 Journal of Organic Chemistry, 67, 4, 1359-1367 2002/02 Refereed English Disclose to all
Ogawa M, Hatano K, Oishi S, Miyake Y, Kawasumi Y, Ito K, Fujii N, Iida H Ogawa M, Hatano K, Oishi S, Miyake Y, Kawasumi Y, Ito K, Fujii N, Iida H Ogawa M, Hatano K, Oishi S, Miyake Y, Kawasumi Y, Ito K, Fujii N, Iida H Direct single step F-18 fluorination of peptides. Direct single step F-18 fluorination of peptides. Direct single step F-18 fluorination of peptides. Journal of Nuclear Medicine, 43, 5, 137P Journal of Nuclear Medicine, 43, 5, 137P Journal of Nuclear Medicine, 43, 5, 137P 2002 Refereed Disclose to all
S. Oishi; A. Niida; T. Kamano; Y. Miwa; T. Taga; Y. Odagaki; N. Hamanaka; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; N. Fujii Oishi S, Niida A, Kamano T, Miwa Y, Taga T, Odagaki Y, Hamanaka N, Yamamoto M, Ajito K, Tamamura H, Otaka A, Fujii N S. Oishi; A. Niida; T. Kamano; Y. Miwa; T. Taga; Y. Odagaki; N. Hamanaka; M. Yamamoto; K. Ajito; H. Tamamura; A. Otaka; N. Fujii Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres Journal of the Chemical Society. Perkin Transactions 1, 15, 1786-1793 Journal of the Chemical Society-Perkin Transactions 1, 15, 1786-1793 Journal of the Chemical Society. Perkin Transactions 1, 15, 1786-1793 2002 Refereed English Disclose to all
H. Tamamura; M. Sugioka; Y. Odagaki; A. Omagari; Y. Kan; S. Oishi; H. Nakashima; N. Yamamoto; S.C. Peiper; N. Hamanaka; A. Otaka; N. Fujii Tamamura H, Sugioka M, Odagaki Y, Omagari A, Kan Y, Oishi S, Nakashima H, Yamamoto N, Peiper SC, Hamanaka N, Otaka A, Fujii N H. Tamamura; M. Sugioka; Y. Odagaki; A. Omagari; Y. Kan; S. Oishi; H. Nakashima; N. Yamamoto; S.C. Peiper; N. Hamanaka; A. Otaka; N. Fujii Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity Bioorganic and Medicinal Chemistry Letters, 11, 3, 359-362 Bioorganic & Medicinal Chemistry Letters, 11, 3, 359-362 Bioorganic and Medicinal Chemistry Letters, 11, 3, 359-362 2001 Refereed English Disclose to all
H. Tamamura; M. Sugioka; Y. Odagaki; A. Omagari; Y. Kan; S. Oishi; H. Nakashima; N. Yamamoto; S.C. Peiper; N. Hamanaka; A. Otaka; N. Fujii Tamamura H, Sugioka M, Odagaki Y, Omagari A, Kan Y, Oishi S, Nakashima H, Yamamoto N, Peiper SC, Hamanaka N, Otaka A, Fujii N H. Tamamura; M. Sugioka; Y. Odagaki; A. Omagari; Y. Kan; S. Oishi; H. Nakashima; N. Yamamoto; S.C. Peiper; N. Hamanaka; A. Otaka; N. Fujii Erratum: Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity (Bioorganic & Medical Chemistry Letters 11 (2001) (359) PII: S0960894X000 Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity (vol 11, pg 359, 2001) Erratum: Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity (Bioorganic & Medical Chemistry Letters 11 (2001) (359) PII: S0960894X000 Bioorganic and Medicinal Chemistry Letters, 11, 17, 2409 Bioorganic & Medicinal Chemistry Letters, 11, 17, 2409 Bioorganic and Medicinal Chemistry Letters, 11, 17, 2409 2001 Refereed English Disclose to all
A. Otaka; H. Watanabe; A. Yukimasa; S. Oishi; H. Tamamura; N. Fujii Otaka A, Watanabe H, Yukimasa A, Oishi S, Tamamura H, Fujii N A. Otaka; H. Watanabe; A. Yukimasa; S. Oishi; H. Tamamura; N. Fujii New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under \\'reduction-oxidative alkylation (R-OA)\\' conditions New access to alpha-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under 'reduction-oxidative alkylation (R-OA)' conditions New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under \\'reduction-oxidative alkylation (R-OA)\\' conditions Tetrahedron Letters, 42, 32, 5443-5446 Tetrahedron Letters, 42, 32, 5443-5446 Tetrahedron Letters, 42, 32, 5443-5446 2001 Refereed English Disclose to all
S. Oishi; H. Tamamura; M. Yamashita; Y. Odagaki; N. Hamanaka; A. Otaka; N. Fujii Oishi S, Tamamura H, Yamashita M, Odagaki Y, Hamanaka N, Otaka A, Fujii N S. Oishi; H. Tamamura; M. Yamashita; Y. Odagaki; N. Hamanaka; A. Otaka; N. Fujii Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu Journal of the Chemical Society. Perkin Transactions 1, 19, 2445-2451 Journal of the Chemical Society-Perkin Transactions 1, 19, 2445-2451 Journal of the Chemical Society. Perkin Transactions 1, 19, 2445-2451 2001 Refereed English Disclose to all
H. Ohno; A. Toda; S. Oishi; T. Tanaka; Y. Takemoto; N. Fujii; T. Ibuka Ohno H, Toda A, Oishi S, Tanaka T, Takemoto Y, Fujii N, Ibuka T H. Ohno; A. Toda; S. Oishi; T. Tanaka; Y. Takemoto; N. Fujii; T. Ibuka Novel synthesis of chiral terminal allenes via palladium(o)catalyzed reduction of mesylates of 2-bromoalk-2-en-1-ols bearing a protected amino group, using diethylzinc Novel synthesis of chiral terminal allenes via palladium(0)-catalyzed reduction of mesylates of 2-bromoalk-2-en-1-ols bearing a protected amino group, using diethylzinc Novel synthesis of chiral terminal allenes via palladium(o)catalyzed reduction of mesylates of 2-bromoalk-2-en-1-ols bearing a protected amino group, using diethylzinc Tetrahedron Letters, 41, 26, 5131-5134 Tetrahedron Letters, 41, 26, 5131-5134 Tetrahedron Letters, 41, 26, 5131-5134 2000 Refereed English Disclose to all
H. Tamamura; A. Omagari; S. Oishi; T. Kanamoto; N. Yamamoto; S.C. Peiper; H. Nakashima; A. Otaka; N. Fujii Tamamura H, Omagari A, Oishi S, Kanamoto T, Yamamoto N, Peiper SC, Nakashima H, Otaka A, Fujii N H. Tamamura; A. Omagari; S. Oishi; T. Kanamoto; N. Yamamoto; S.C. Peiper; H. Nakashima; A. Otaka; N. Fujii Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes Bioorganic and Medicinal Chemistry Letters, 10, 23, 2633-2637 Bioorganic & Medicinal Chemistry Letters, 10, 23, 2633-2637 Bioorganic and Medicinal Chemistry Letters, 10, 23, 2633-2637 2000 Refereed English Disclose to all
S. Inuki; S. Oishi; N. Fujii; H. Ohno S. Inuki; S. Oishi; N. Fujii; H. Ohno Total synthesis of ((±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group (Oroganic Letters (2008) 10 (5239)) Total synthesis of ((±)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group (Oroganic Letters (2008) 10 (5239)) Organic Letters, 13, 8, 2145- , 13, 8, 2145- Organic Letters, 13, 8, 2145- 2011 Refereed English Disclose to all
A. Dar; A. Schajnovitz; K. Lapid; A. Kalinkovich; T. Itkin; A. Ludin; W.-M. Kao; M. Battista; M. Tesio; O. Kollet; N.N. Cohen; R. Margalit; E.C. Buss; F. Baleux; S. Oishi; N. Fujii; A. Larochelle; C.E. Dunbar; H.E. Broxmeyer; P.S. Frenette; T. Lapidot A. Dar; A. Schajnovitz; K. Lapid; A. Kalinkovich; T. Itkin; A. Ludin; W.-M. Kao; M. Battista; M. Tesio; O. Kollet; N.N. Cohen; R. Margalit; E.C. Buss; F. Baleux; S. Oishi; N. Fujii; A. Larochelle; C.E. Dunbar; H.E. Broxmeyer; P.S. Frenette; T. Lapidot Erratum: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (Leukemia (April 2011) DOI:10.1038/leu.2011.62) Erratum: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (Leukemia (April 2011) DOI:10.1038/leu.2011.62) Leukemia, 25, 8, 1378 , 25, 8, 1378 Leukemia, 25, 8, 1378 2011 Refereed English Disclose to all
大石 真也 大石 真也 Design of peptide- based inhibitors of HIV-1 strains resistant to T-20. Design of peptide- based inhibitors of HIV-1 strains resistant to T-20. J. Biol. Chem. 284/8, 4914-4920, 284, 8, 4914-4920 , 284, 8, 4914-4920 J. Biol. Chem. 284/8, 4914-4920, 284, 8, 4914-4920 2009 Refereed English Disclose to all
大石 真也 大石 真也 Development of novel GPR54 agonists with resistance to degradation by matrix metalloproteinase. Development of novel GPR54 agonists with resistance to degradation by matrix metalloproteinase. J. Med. Chem. 51/23, 7645-7649, 51, 23, 7645-7649 , 51, 23, 7645-7649 J. Med. Chem. 51/23, 7645-7649, 51, 23, 7645-7649 2008 Refereed English Disclose to all
H. Ohno; Y. Ohta; S. Oishi; N. Fujii H. Ohno; Y. Ohta; S. Oishi; N. Fujii Erratum: Direct synthesis of 2-(aminomethyl)-indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions (Angewandte Chemie - International Edition (2007) 46, (2295-2298) DOI: 10.1002/anie.200604342) Erratum: Direct synthesis of 2-(aminomethyl)-indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions (Angewandte Chemie - International Edition (2007) 46, (2295-2298) DOI: 10.1002/anie.200604342) Angewandte Chemie - International Edition, 46, 18, 3173- , 46, 18, 3173- Angewandte Chemie - International Edition, 46, 18, 3173- 2007 Refereed English Disclose to all
大石 真也 大石 真也 SmI2-mediated reduction of γ,γ-difluoro-α,β-enoates and its application to the synthesis of (Z)-fluoroalkene-type dipeptide isosteres. SmI2-mediated reduction of γ,γ-difluoro-α,β-enoates and its application to the synthesis of (Z)-fluoroalkene-type dipeptide isosteres. J. Org. Chem. 69/5, 1634-1645, 69, 5, 1634-1645 , 69, 5, 1634-1645 J. Org. Chem. 69/5, 1634-1645, 69, 5, 1634-1645 2004 Refereed English Disclose to all
A. Otaka; A. Yukimasa; J. Watanabe; Y. Sasaki; S. Oishi; H. Tamamura; N. Fujii A. Otaka; A. Yukimasa; J. Watanabe; Y. Sasaki; S. Oishi; H. Tamamura; N. Fujii Application of samarium diiodide (SmI<sub>2</sub>)-induced reduction of α-acetoxy-α,β-enoates with α-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives Application of samarium diiodide (SmI<sub>2</sub>)-induced reduction of α-acetoxy-α,β-enoates with α-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives Chemical Communications, 15, 1834-1835 , 15, 1834-1835 Chemical Communications, 15, 1834-1835 2003 Refereed English Disclose to all
M. Kawaguchi; R. Hosotani; S. Ohishi; N. Fujii; S. Singh Tulachan; M. Koizumi; E. Toyoda; T. Masui; S. Nakajima; S. Tsuji; J. Ida; K. Fujimoto; M. Wada; R. Doi; M. Imamura M. Kawaguchi; R. Hosotani; S. Ohishi; N. Fujii; S. Singh Tulachan; M. Koizumi; E. Toyoda; T. Masui; S. Nakajima; S. Tsuji; J. Ida; K. Fujimoto; M. Wada; R. Doi; M. Imamura A novel synthetic Arg-Gly-Asp-containing peptide cyclo(-RGDf=V-) is the potent inhibitor of angiogenesis A novel synthetic Arg-Gly-Asp-containing peptide cyclo(-RGDf=V-) is the potent inhibitor of angiogenesis Biochemical and Biophysical Research Communications, 288, 3, 711-717 , 288, 3, 711-717 Biochemical and Biophysical Research Communications, 288, 3, 711-717 2001/11/02 Refereed English Disclose to all
H. Ohno; M. Anzai; A. Toda; S. Ohishi; N. Fujii; T. Tanaka; Y. Takemoto; T. Ibuka H. Ohno; M. Anzai; A. Toda; S. Ohishi; N. Fujii; T. Tanaka; Y. Takemoto; T. Ibuka Stereoselective synthesis of 2-alkenylaziridines and 2-alkenylazetidines by palladium-catalyzed intramolecular amination of α- and β-amino allenes Stereoselective synthesis of 2-alkenylaziridines and 2-alkenylazetidines by palladium-catalyzed intramolecular amination of α- and β-amino allenes Journal of Organic Chemistry, 66, 14, 4904-4914 , 66, 14, 4904-4914 Journal of Organic Chemistry, 66, 14, 4904-4914 2001/07/13 Refereed English Disclose to all

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NAOE SAORI, SAITO TATSUO, UCHIYAMA MASANOBU, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 斉藤竜男, 内山真伸, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, SAITO TATSUO, UCHIYAMA MASANOBU, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 次世代を担う有機化学シンポジウム講演要旨集, 13th, 14-15 次世代を担う有機化学シンポジウム講演要旨集, 13th, 14-15 次世代を担う有機化学シンポジウム講演要旨集, 13th, 14-15 2015/05/22 Japanese Disclose to all
YAMAMURA TAKASHI, WAKABAYASHI YOSHIHIRO, MISU RYOSUKE, OISHI SHIN'YA, OKURA SATOSHI, FUJII NOBUTAKA, OKAMURA HIROAKI 山村崇, 若林嘉浩, 三須良介, 大石真也, 大蔵聡, 藤井信孝, 岡村裕昭 YAMAMURA TAKASHI, WAKABAYASHI YOSHIHIRO, MISU RYOSUKE, OISHI SHIN'YA, OKURA SATOSHI, FUJII NOBUTAKA, OKAMURA HIROAKI ニューロキニン作動薬を用いた新たな卵胞発育制御技術の開発研究 ニューロキニン作動薬を用いた新たな卵胞発育制御技術の開発研究 ニューロキニン作動薬を用いた新たな卵胞発育制御技術の開発研究 日本畜産学会大会講演要旨, 119th, 197 日本畜産学会大会講演要旨, 119th, 197 日本畜産学会大会講演要旨, 119th, 197 2015/03/28 Japanese Disclose to all
MATSUYAMA SHUICHI, OKURA SATOSHI, OISHI SHIN'YA, KIMURA KOJI 松山秀一, 大蔵聡, 大石真也, 木村康二 MATSUYAMA SHUICHI, OKURA SATOSHI, OISHI SHIN'YA, KIMURA KOJI ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の静脈内への頻回投与が性腺刺激ホルモン分泌および排卵成績に及ぼす影響 ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の静脈内への頻回投与が性腺刺激ホルモン分泌および排卵成績に及ぼす影響 ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の静脈内への頻回投与が性腺刺激ホルモン分泌および排卵成績に及ぼす影響 日本はい移植学雑誌, 37, 1, 34 日本はい移植学雑誌, 37, 1, 34 日本はい移植学雑誌, 37, 1, 34 2015/01/21 Japanese Disclose to all
KOBAYASHI YUKA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 小林由佳, 大石真也, 大野浩章, 藤井信孝 KOBAYASHI YUKA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 鉄(II)イオン配位性ペプチドの設計と機能評価 鉄(II)イオン配位性ペプチドの設計と機能評価 鉄(II)イオン配位性ペプチドの設計と機能評価 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-PM090S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-PM090S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-PM090S 2015 Japanese Disclose to all
MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 松田優佳, 直江紗織, 大石真也, 藤井信孝, 大野浩章 MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応による4,7‐二置換インドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応による4,7‐二置換インドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応による4,7‐二置換インドール骨格の構築 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26S-AM05S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26S-AM05S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26S-AM05S 2015 Japanese Disclose to all
HONDA MAHO, MIYAGAKI JUN, YOSHIMITSU YUJI, IWATA AKIRA, OTSUKI KAZUHIRO, MARUYAMA TOORU, NAKAMURA SHIN'YA, NAKANISHI ISAO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 本田真歩, 宮垣潤, 吉光佑二, 岩田顕, 大槻和裕, 丸山透, 中村真也, 仲西功, 大石真也, 大野浩章, 藤井信孝 HONDA MAHO, MIYAGAKI JUN, YOSHIMITSU YUJI, IWATA AKIRA, OTSUKI KAZUHIRO, MARUYAMA TOORU, NAKAMURA SHIN'YA, NAKANISHI ISAO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA クロスメタセシス反応を利用したスフィンゴシンキナーゼ阻害剤の創製研究 クロスメタセシス反応を利用したスフィンゴシンキナーゼ阻害剤の創製研究 クロスメタセシス反応を利用したスフィンゴシンキナーゼ阻害剤の創製研究 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM13 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM13 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM13 2015 Japanese Disclose to all
KUROYANAGI TOMOKO, OISHI SHIN'YA, KUBO TATSUHIKO, KOBAYASHI YUKA, MISU RYOSUKE, ONO HIROAKI, MONTPAS NICOLAS, HEVEKER NIKOLAUS, YOSHIKAWA YASUSHI, FURUYA TOSHIO, FUJII NOBUTAKA 黒柳友子, 大石真也, 久保達彦, 小林由佳, 三須良介, 大野浩章, MONTPAS Nicolas, HEVEKER Nikolaus, 吉川寧, 古谷利夫, 藤井信孝 KUROYANAGI TOMOKO, OISHI SHIN'YA, KUBO TATSUHIKO, KOBAYASHI YUKA, MISU RYOSUKE, ONO HIROAKI, MONTPAS NICOLAS, HEVEKER NIKOLAUS, YOSHIKAWA YASUSHI, FURUYA TOSHIO, FUJII NOBUTAKA 新規CXCR7選択的リガンドの創製:CXCR4拮抗剤からの受容体選択性の変換 新規CXCR7選択的リガンドの創製:CXCR4拮抗剤からの受容体選択性の変換 新規CXCR7選択的リガンドの創製:CXCR4拮抗剤からの受容体選択性の変換 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM12 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM12 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-AM12 2015 Japanese Disclose to all
NOGUCHI TARO, OISHI SHIN'YA, HONDA KAORI, KONDO YASUMITSU, SAITO TAMIO, ONO HIROAKI, OSADA HIROYUKI, FUJII NOBUTAKA 野口太朗, 大石真也, 本田香織, 近藤恭光, 斎藤臣雄, 大野浩章, 長田裕之, 藤井信孝 NOGUCHI TARO, OISHI SHIN'YA, HONDA KAORI, KONDO YASUMITSU, SAITO TAMIO, ONO HIROAKI, OSADA HIROYUKI, FUJII NOBUTAKA 天然物の鏡像体化合物群の活用を目指した新規スクリーニング法の開発 天然物の鏡像体化合物群の活用を目指した新規スクリーニング法の開発 天然物の鏡像体化合物群の活用を目指した新規スクリーニング法の開発 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-AM275 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-AM275 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.27PB-AM275 2015 Japanese Disclose to all
YAMAMOTO KOKI, OISHI SHIN'YA, MISU RYOSUKE, YAMADA AI, NOGUCHI TARO, ONO HIROAKI, YAMAMURA TAKASHI, OKAMURA HIROAKI, MATSUDA NIKO, OKURA SATOSHI, FUJII NOBUTAKA 山本昂輝, 大石真也, 三須良介, 山田愛, 野口太朗, 大野浩章, 山村崇, 岡村裕昭, 松田二子, 大蔵聡, 藤井信孝 YAMAMOTO KOKI, OISHI SHIN'YA, MISU RYOSUKE, YAMADA AI, NOGUCHI TARO, ONO HIROAKI, YAMAMURA TAKASHI, OKAMURA HIROAKI, MATSUDA NIKO, OKURA SATOSHI, FUJII NOBUTAKA 新規ニューロキニン‐3受容体アゴニストの創製と繁殖中枢制御への応用 新規ニューロキニン‐3受容体アゴニストの創製と繁殖中枢制御への応用 新規ニューロキニン‐3受容体アゴニストの創製と繁殖中枢制御への応用 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-PM06S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-PM06S 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.28S-PM06S 2015 Japanese Disclose to all
TAGUCHI MASAMITSU, TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 田口将光, 時水勇輔, 大石真也, 藤井信孝, 大野浩章 TAGUCHI MASAMITSU, TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインの三連続環化反応による縮環カルバゾールの合成 金触媒を用いた共役ジインの三連続環化反応による縮環カルバゾールの合成 金触媒を用いた共役ジインの三連続環化反応による縮環カルバゾールの合成 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26K-PM12 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26K-PM12 日本薬学会年会要旨集(CD-ROM), 135th, ROMBUNNO.26K-PM12 2015 Japanese Disclose to all
OISHI SHIN'YA 大石真也 OISHI SHIN'YA 抗腫瘍活性ペプチドの全合成とその応用 抗腫瘍活性ペプチドの全合成とその応用 抗腫瘍活性ペプチドの全合成とその応用 上原記念生命科学財団研究報告集(CD-ROM), 28, ROMBUNNO.15 上原記念生命科学財団研究報告集(CD-ROM), 28, ROMBUNNO.15 上原記念生命科学財団研究報告集(CD-ROM), 28, ROMBUNNO.15 2014/12/05 Japanese Disclose to all
KUROYANAGI TOMOKO, OISHI SHIN'YA, KUBO TATSUHIKO, KOBAYASHI YUKA, MISU RYOSUKE, ONO HIROAKI, NICOLAS MONTPAS, NIKOLAUS HEVEKER, YOSHIKAWA YASUSHI, FURUYA TOSHIO, FUJII NOBUTAKA 黒柳友子, 大石真也, 久保達彦, 小林由佳, 三須良介, 大野浩章, NICOLAS Montpas, NIKOLAUS Heveker, 吉川寧, 古谷利夫, 藤井信孝 KUROYANAGI TOMOKO, OISHI SHIN'YA, KUBO TATSUHIKO, KOBAYASHI YUKA, MISU RYOSUKE, ONO HIROAKI, NICOLAS MONTPAS, NIKOLAUS HEVEKER, YOSHIKAWA YASUSHI, FURUYA TOSHIO, FUJII NOBUTAKA 環状ペンタペプチド骨格を有する新規CXCR7選択的リガンドの創製 環状ペンタペプチド骨格を有する新規CXCR7選択的リガンドの創製 環状ペンタペプチド骨格を有する新規CXCR7選択的リガンドの創製 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 164 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 164 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 164 2014/11/07 Japanese Disclose to all
HONDA MAHO, MIYAGAKI JUN, YOSHIMITSU YUJI, IWATA AKIRA, OTSUKI KAZUHIRO, MARUYAMA TOORU, NAKAMURA SHIN'YA, NAKANISHI ISAO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 本田真歩, 宮垣潤, 吉光佑二, 岩田顕, 大槻和裕, 丸山透, 中村真也, 仲西功, 大石真也, 大野浩章, 藤井信孝 HONDA MAHO, MIYAGAKI JUN, YOSHIMITSU YUJI, IWATA AKIRA, OTSUKI KAZUHIRO, MARUYAMA TOORU, NAKAMURA SHIN'YA, NAKANISHI ISAO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究 スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究 スフィンゴシンキナーゼ阻害活性を有するJaspine B誘導体の構造活性相関研究 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 119 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 119 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 119 2014/11/07 Japanese Disclose to all
MATSUURA YOSHIHIRO, TAKEMOTO SUZUHO, MATSUE SAKI, SUMIYOSHI TAKAAKI, NAGAOKA YASUO, UESATO SHIN'ICHI, ENARI MASATO, NOGUCHI TARO, OISHI SHIN'YA, FUJII NOBUTAKA 松浦佳宏, 竹本涼穂, 松江紗希, 住吉孝明, 長岡康夫, 上里新一, 江成政人, 野口太朗, 大石真也, 藤井信孝 MATSUURA YOSHIHIRO, TAKEMOTO SUZUHO, MATSUE SAKI, SUMIYOSHI TAKAAKI, NAGAOKA YASUO, UESATO SHIN'ICHI, ENARI MASATO, NOGUCHI TARO, OISHI SHIN'YA, FUJII NOBUTAKA p53の機能を活性化する新規タンパク‐タンパク結合阻害剤の探索研究 p53の機能を活性化する新規タンパク‐タンパク結合阻害剤の探索研究 p53の機能を活性化する新規タンパク‐タンパク結合阻害剤の探索研究 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 93 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 93 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 93 2014/11/07 Japanese Disclose to all
OKAZAKI SHIHO, MIZUHARA TSUKASA, SHIMURA KAZUYA, MURAYAMA HIROTO, MATSUOKA MASAO, ONO HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA 岡崎志穂, 水原司, 志村和也, 村山大人, 松岡雅雄, 大野浩章, 大石真也, 藤井信孝 OKAZAKI SHIHO, MIZUHARA TSUKASA, SHIMURA KAZUYA, MURAYAMA HIROTO, MATSUOKA MASAO, ONO HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA 新規抗HIV剤を指向したベンゾイソチアゾロピリミジン誘導体の構造活性相関研究 新規抗HIV剤を指向したベンゾイソチアゾロピリミジン誘導体の構造活性相関研究 新規抗HIV剤を指向したベンゾイソチアゾロピリミジン誘導体の構造活性相関研究 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 102 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 102 メディシナルケミストリーシンポジウム講演要旨集, 32nd, 102 2014/11/07 Japanese Disclose to all
OISHI SHIN'YA, FUJII NOBUTAKA 大石真也, 藤井信孝 OISHI SHIN'YA, FUJII NOBUTAKA ペプチド化学の新潮流 I ウイルス変異に基づく抗HIV活性ペプチドのデザイン ペプチド化学の新潮流 I ウイルス変異に基づく抗HIV活性ペプチドのデザイン ペプチド化学の新潮流 I ウイルス変異に基づく抗HIV活性ペプチドのデザイン 化学工業, 65, 11, 857-861 化学工業, 65, 11, 857-861 化学工業, 65, 11, 857-861 2014/11/01 Japanese Disclose to all
YAMADA SHINTARO, SHIMOJIMA MASAYUKI, NARITA RYO, OISHI SHIN'YA, TAKAHASHI KIYOHIRO, KATO HIROMI, SAIJO MASAYUKI, FUJITA TAKASHI 山田辰太郎, 下島昌幸, 成田亮, 大石真也, 高橋清大, 加藤博己, 西條政幸, 藤田尚志 YAMADA SHINTARO, SHIMOJIMA MASAYUKI, NARITA RYO, OISHI SHIN'YA, TAKAHASHI KIYOHIRO, KATO HIROMI, SAIJO MASAYUKI, FUJITA TAKASHI ダニ媒介性ウイルスの非構造タンパク質による自然免疫抑制機構 ダニ媒介性ウイルスの非構造タンパク質による自然免疫抑制機構 ダニ媒介性ウイルスの非構造タンパク質による自然免疫抑制機構 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 389 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 389 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 389 2014/10/31 Japanese Disclose to all
KATO FUMIHIRO, ISHIDA YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, MIURA TOMOYUKI, IGARASHI TATSUHIKO, HISHIKI TAKAYUKI 加藤文博, 石田裕樹, 大石真也, 藤井信孝, 三浦智行, 五十嵐樹彦, 日紫喜隆行 KATO FUMIHIRO, ISHIDA YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, MIURA TOMOYUKI, IGARASHI TATSUHIKO, HISHIKI TAKAYUKI bromocriptineによる抗デングウイルス活性機構の解析 bromocriptineによる抗デングウイルス活性機構の解析 bromocriptineによる抗デングウイルス活性機構の解析 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 253 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 253 日本ウイルス学会学術集会プログラム・抄録集, 62nd, 253 2014/10/31 Japanese Disclose to all
NAMIKAWA RYOTA, OISHI SHIN'YA, MISU RYOSUKE, ONO HIROAKI, FUJII NOBUTAKA 並河亮太, 大石真也, 三須良介, 大野浩章, 藤井信孝 NAMIKAWA RYOTA, OISHI SHIN'YA, MISU RYOSUKE, ONO HIROAKI, FUJII NOBUTAKA ペプチド結合のN‐メチル化反応を利用したIB‐01212の合成研究 ペプチド結合のN‐メチル化反応を利用したIB‐01212の合成研究 ペプチド結合のN‐メチル化反応を利用したIB‐01212の合成研究 反応と合成の進歩シンポジウム講演要旨集, 40th, 31 反応と合成の進歩シンポジウム講演要旨集, 40th, 31 反応と合成の進歩シンポジウム講演要旨集, 40th, 31 2014/10/22 Japanese Disclose to all
TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 時水勇輔, 大石真也, 藤井信孝, 大野浩章 TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 反応と合成の進歩シンポジウム講演要旨集, 40th, 23 反応と合成の進歩シンポジウム講演要旨集, 40th, 23 反応と合成の進歩シンポジウム講演要旨集, 40th, 23 2014/10/22 Japanese Disclose to all
MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 松田優佳, 直江紗織, 大石真也, 藤井信孝, 大野浩章 MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 反応と合成の進歩シンポジウム講演要旨集, 40th, 43 反応と合成の進歩シンポジウム講演要旨集, 40th, 43 反応と合成の進歩シンポジウム講演要旨集, 40th, 43 2014/10/22 Japanese Disclose to all
MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 松田優佳, 直江紗織, 大石真也, 藤井信孝, 大野浩章 MATSUDA YUKA, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 金触媒を用いた共役ジインとピロールの分子間[4+2]型反応によるインドール骨格の構築 有機合成化学セミナー講演予稿集, 31st, 89 有機合成化学セミナー講演予稿集, 31st, 89 有機合成化学セミナー講演予稿集, 31st, 89 2014/09/17 Japanese Disclose to all
KATO MASAO, SUETOMI YUTA, ITO DAISUKE, SASAKI TAKUYA, NAMBA YOSUKE, MISU RYOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUDA NIKO, OKURA SATOSHI 加藤雅大, 末富祐太, 伊藤太祐, 佐々木拓弥, 難波陽介, 三須良介, 大石真也, 藤井信孝, 松田二子, 大蔵聡 KATO MASAO, SUETOMI YUTA, ITO DAISUKE, SASAKI TAKUYA, NAMBA YOSUKE, MISU RYOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUDA NIKO, OKURA SATOSHI ニューロキニンB作動薬の末梢投与は黒毛和種雌ウシの黄体形成ホルモン分泌および卵胞発育を促進する ニューロキニンB作動薬の末梢投与は黒毛和種雌ウシの黄体形成ホルモン分泌および卵胞発育を促進する ニューロキニンB作動薬の末梢投与は黒毛和種雌ウシの黄体形成ホルモン分泌および卵胞発育を促進する J Reprod Dev, 60, Suppl Japanese Issue, J100 J Reprod Dev, 60, Suppl Japanese Issue, J100 J Reprod Dev, 60, Suppl Japanese Issue, J100 2014/08/10 Japanese Disclose to all
TAKENAGA MITSUKO, TAKEUCHI TOMOKI, TOKURA YUKIE, HAMAGUCHI AKEMI, YAMAMOTO YUKI, OTA YUKI, ASAI DAISUKE, NAKASHIMA HIDEKI, OISHI SHIN'YA, FUJII NOBUTAKA 武永美津子, 竹内智起, 都倉享恵, 濱口明美, 山本有貴, 太田有紀, 淺井大輔, 中島秀喜, 大石真也, 藤井信孝 TAKENAGA MITSUKO, TAKEUCHI TOMOKI, TOKURA YUKIE, HAMAGUCHI AKEMI, YAMAMOTO YUKI, OTA YUKI, ASAI DAISUKE, NAKASHIMA HIDEKI, OISHI SHIN'YA, FUJII NOBUTAKA 新規KSP阻害剤の抗腫瘍効果に関する研究(第2報) 新規KSP阻害剤の抗腫瘍効果に関する研究(第2報) 新規KSP阻害剤の抗腫瘍効果に関する研究(第2報) 日本DDS学会学術集会プログラム予稿集, 30th, 222 日本DDS学会学術集会プログラム予稿集, 30th, 222 日本DDS学会学術集会プログラム予稿集, 30th, 222 2014/07/01 Japanese Disclose to all
KOIDE TAKAKI, ZENDA MIYU, OISHI SHIN'YA, MASUDA RYO, FUJII NOBUTAKA, YASUI HIROYUKI 小出隆規, 全田未悠, 大石真也, 増田亮, 藤井信孝, 安井裕之 KOIDE TAKAKI, ZENDA MIYU, OISHI SHIN'YA, MASUDA RYO, FUJII NOBUTAKA, YASUI HIROYUKI コラーゲンの細線維化を阻害するプラチナ錯体 コラーゲンの細線維化を阻害するプラチナ錯体 コラーゲンの細線維化を阻害するプラチナ錯体 Biomed Res Trace Elem, 25, 2, 61 Biomed Res Trace Elem, 25, 2, 61 Biomed Res Trace Elem, 25, 2, 61 2014/06/01 Japanese Disclose to all
TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 時水勇輔, 大石真也, 藤井信孝, 大野浩章 TOKIMIZU YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 金触媒によるアジドイナミドの連続環化反応を用いたインドロキノリン骨格の一挙構築 次世代を担う有機化学シンポジウム講演要旨集, 12th, 28-29 次世代を担う有機化学シンポジウム講演要旨集, 12th, 28-29 次世代を担う有機化学シンポジウム講演要旨集, 12th, 28-29 2014/05/23 Japanese Disclose to all
MURAKAMI NAOYUKI, TODOKORO TAKEHIKO, NAKAGAWA TAKUYA, FUKUDA KATSUHARU, MATSUMURA KENGO, IRIE MOTOKO, KOBAYASHI YUKA, TSUTSUMI HIROKO, OISHI SHIN'YA, FUJII NOBUTAKA, HATA YOJI 村上直之, 戸所健彦, 中川拓哉, 福田克治, 松村憲吾, 入江元子, 小林由佳, 堤浩子, 大石真也, 藤井信孝, 秦洋二 MURAKAMI NAOYUKI, TODOKORO TAKEHIKO, NAKAGAWA TAKUYA, FUKUDA KATSUHARU, MATSUMURA KENGO, IRIE MOTOKO, KOBAYASHI YUKA, TSUTSUMI HIROKO, OISHI SHIN'YA, FUJII NOBUTAKA, HATA YOJI 麹菌が産生する鉄キレート環状ペプチドデフェリフェリクリシンの大量生産技術の開発―培地成分のDfcy生成への影響について― 麹菌が産生する鉄キレート環状ペプチドデフェリフェリクリシンの大量生産技術の開発―培地成分のDfcy生成への影響について― 麹菌が産生する鉄キレート環状ペプチドデフェリフェリクリシンの大量生産技術の開発―培地成分のDfcy生成への影響について― 日本農芸化学会大会講演要旨集(Web), 2014, 3A14A10 (WEB ONLY) 日本農芸化学会大会講演要旨集(Web), 2014, 3A14A10 (WEB ONLY) 日本農芸化学会大会講演要旨集(Web), 2014, 3A14A10 (WEB ONLY) 2014/03/05 Japanese Disclose to all
YOSHIKAWA YASUSHI, OISHI SHIN'YA, KUBO TATSUHIKO, TANAHARA NORIKO, FUJII NOBUTAKA, FURUYA TOSHIO 吉川寧, 大石真也, 久保達彦, 棚原憲子, 藤井信孝, 古谷利夫 YOSHIKAWA YASUSHI, OISHI SHIN'YA, KUBO TATSUHIKO, TANAHARA NORIKO, FUJII NOBUTAKA, FURUYA TOSHIO Gタンパク質共役型受容体の立体構造モデル構築手法の開発とCXCR7バーチャルスクリーニングへの応用 Gタンパク質共役型受容体の立体構造モデル構築手法の開発とCXCR7バーチャルスクリーニングへの応用 Gタンパク質共役型受容体の立体構造モデル構築手法の開発とCXCR7バーチャルスクリーニングへの応用 GPCR研究会プログラム・抄録集, 11th, 22 GPCR研究会プログラム・抄録集, 11th, 22 GPCR研究会プログラム・抄録集, 11th, 22 2014 Japanese Disclose to all
YAMAMOTO KOKI, MISU RYOSUKE, NOGUCHI TARO, ONO HIROAKI, OISHI SHIN'YA, YAMAMURA TAKASHI, OKAMURA HIROAKI, FUJII NOBUTAKA 山本昂輝, 三須良介, 野口太朗, 大野浩章, 大石真也, 山村崇, 岡村裕昭, 藤井信孝 YAMAMOTO KOKI, MISU RYOSUKE, NOGUCHI TARO, ONO HIROAKI, OISHI SHIN'YA, YAMAMURA TAKASHI, OKAMURA HIROAKI, FUJII NOBUTAKA ニューロキニン‐3受容体アゴニストの構造活性相関研究 ニューロキニン‐3受容体アゴニストの構造活性相関研究 ニューロキニン‐3受容体アゴニストの構造活性相関研究 GPCR研究会プログラム・抄録集, 11th, 39 GPCR研究会プログラム・抄録集, 11th, 39 GPCR研究会プログラム・抄録集, 11th, 39 2014 Japanese Disclose to all
YASUDA YORINOBU, NAWATA YUMI, ARAKAWA TAKEAKI, SHIMADA SAYAKA, HATTORI AKIRA, NISHIMURA SHIN'ICHI, OISHI SHIN'YA, FUJII NOBUTAKA, KAKEYA HIDEAKI 安田順信, 縄田有美, 荒川武明, 嶋田清香, 服部明, 西村慎一, 大石真也, 藤井信孝, 掛谷秀昭 YASUDA YORINOBU, NAWATA YUMI, ARAKAWA TAKEAKI, SHIMADA SAYAKA, HATTORI AKIRA, NISHIMURA SHIN'ICHI, OISHI SHIN'YA, FUJII NOBUTAKA, KAKEYA HIDEAKI 新規低酸素誘導因子HIF阻害剤の探索と構造活性相関研究 新規低酸素誘導因子HIF阻害剤の探索と構造活性相関研究 新規低酸素誘導因子HIF阻害剤の探索と構造活性相関研究 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.29AMS-067S 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.29AMS-067S 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.29AMS-067S 2014 Japanese Disclose to all
MISU RYOSUKE, OISHI SHIN'YA, YAMADA AI, YAMAMOTO KOKI, NOGUCHI TARO, ONO HIROAKI, YAMAMURA TAKASHI, OKAMURA HIROAKI, MATSUDA NIKO, OKURA SATOSHI, FUJII NOBUTAKA 三須良介, 大石真也, 山田愛, 山本昂輝, 野口太朗, 大野浩章, 山村崇, 岡村裕昭, 松田二子, 大蔵聡, 藤井信孝 MISU RYOSUKE, OISHI SHIN'YA, YAMADA AI, YAMAMOTO KOKI, NOGUCHI TARO, ONO HIROAKI, YAMAMURA TAKASHI, OKAMURA HIROAKI, MATSUDA NIKO, OKURA SATOSHI, FUJII NOBUTAKA NK3受容体アゴニストの生体内安定性評価と新規誘導体の創製 NK3受容体アゴニストの生体内安定性評価と新規誘導体の創製 NK3受容体アゴニストの生体内安定性評価と新規誘導体の創製 GPCR研究会プログラム・抄録集, 11th, 38 GPCR研究会プログラム・抄録集, 11th, 38 GPCR研究会プログラム・抄録集, 11th, 38 2014 Japanese Disclose to all
TAKENAGA MITSUKO, YAMAMOTO YUKI, TAKEUCHI TOMOKI, OTA YUKI, TOKURA YUKIE, HAMAGUCHI AKEMI, OISHI SHIN'YA, FUJII NOBUTAKA 武永美津子, 山本有貴, 竹内智起, 太田有紀, 都倉享恵, 濱口明美, 大石真也, 藤井信孝 TAKENAGA MITSUKO, YAMAMOTO YUKI, TAKEUCHI TOMOKI, OTA YUKI, TOKURA YUKIE, HAMAGUCHI AKEMI, OISHI SHIN'YA, FUJII NOBUTAKA 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果 新規合成KSP阻害剤のヒト卵巣がんに対する抗腫瘍効果 日本癌治療学会学術集会(CD-ROM), 52nd, ROMBUNNO.P66-3 日本癌治療学会学術集会(CD-ROM), 52nd, ROMBUNNO.P66-3 日本癌治療学会学術集会(CD-ROM), 52nd, ROMBUNNO.P66-3 2014 Japanese Disclose to all
NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの連続環化反応による縮環インドールの一挙合成 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28R-PM05 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28R-PM05 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28R-PM05 2014 Japanese Disclose to all
KANEDA MASAHITO, OISHI SHIN'YA, MISU RYOSUKE, ONO HIROAKI, FUJII NOBUTAKA 金田雅仁, 大石真也, 三須良介, 大野浩章, 藤井信孝 KANEDA MASAHITO, OISHI SHIN'YA, MISU RYOSUKE, ONO HIROAKI, FUJII NOBUTAKA キスペプチン受容体に対する蛍光プローブの創製研究 キスペプチン受容体に対する蛍光プローブの創製研究 キスペプチン受容体に対する蛍光プローブの創製研究 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28L-PM17 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28L-PM17 日本薬学会年会要旨集(CD-ROM), 134th, ROMBUNNO.28L-PM17 2014 Japanese Disclose to all
SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 志村和也, 大石真也, 藤井信孝, 松岡雅雄 SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 抗ウイルス薬感受性に対するHIV感染経路の影響 抗ウイルス薬感受性に対するHIV感染経路の影響 抗ウイルス薬感受性に対するHIV感染経路の影響 日本エイズ学会誌, 15, 4, 505 日本エイズ学会誌, 15, 4, 505 日本エイズ学会誌, 15, 4, 505 2013/11/20 Japanese Disclose to all
OKAZAKI SHIHO, MIZUHARA TSUKASA, KATO TAKAYUKI, HIRAI ATSUSHI, KURIHARA HIDEKI, SHIMADA YASUHIRO, TANIGUCHI MASAHIKO, MAETA HIDEKI, TOGAMI HIROAKI, SHIMURA KAZUYA, MATSUOKA MASAO, TAKEUCHI TOMOKI, ONO HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA 岡崎志穂, 水原司, 加藤貴之, 平井敦, 栗原秀樹, 嶋田泰宏, 谷口雅彦, 前田英樹, 戸上博昭, 志村和也, 松岡雅雄, 竹内智起, 大野浩章, 大石真也, 藤井信孝 OKAZAKI SHIHO, MIZUHARA TSUKASA, KATO TAKAYUKI, HIRAI ATSUSHI, KURIHARA HIDEKI, SHIMADA YASUHIRO, TANIGUCHI MASAHIKO, MAETA HIDEKI, TOGAMI HIROAKI, SHIMURA KAZUYA, MATSUOKA MASAO, TAKEUCHI TOMOKI, ONO HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA 新規フェニルピラゾール誘導体の抗HIV活性に関する構造活性相関研究 新規フェニルピラゾール誘導体の抗HIV活性に関する構造活性相関研究 新規フェニルピラゾール誘導体の抗HIV活性に関する構造活性相関研究 メディシナルケミストリーシンポジウム講演要旨集, 31st, 171 メディシナルケミストリーシンポジウム講演要旨集, 31st, 171 メディシナルケミストリーシンポジウム講演要旨集, 31st, 171 2013/11/01 Japanese Disclose to all
TAKEUCHI TOMOKI, OISHI SHIN'YA, KANEDA MASATO, ONO HIROAKI, NAKAMURA SHIN'YA, NAKANISHI ISAO, YAMANE MASAYOSHI, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 竹内智起, 大石真也, 金田雅仁, 大野浩章, 中村真也, 仲西功, 山根正敏, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOKI, OISHI SHIN'YA, KANEDA MASATO, ONO HIROAKI, NAKAMURA SHIN'YA, NAKANISHI ISAO, YAMANE MASAYOSHI, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 連続縮環型分子の修飾によるKSP阻害剤の溶解性改善 連続縮環型分子の修飾によるKSP阻害剤の溶解性改善 連続縮環型分子の修飾によるKSP阻害剤の溶解性改善 メディシナルケミストリーシンポジウム講演要旨集, 31st, 167 メディシナルケミストリーシンポジウム講演要旨集, 31st, 167 メディシナルケミストリーシンポジウム講演要旨集, 31st, 167 2013/11/01 Japanese Disclose to all
NOGUCHI TARO, OISHI SHIN'YA, HONDA KAORI, KONDO YASUMITSU, SAITO TAMIO, KUBO TATSUHIKO, KANEDA MASATO, ONO HIROAKI, OSADA HIROYUKI, FUJII NOBUTAKA 野口太朗, 大石真也, 本田香織, 近藤恭光, 斎藤臣雄, 久保達彦, 金田雅仁, 大野浩章, 長田裕之, 藤井信孝 NOGUCHI TARO, OISHI SHIN'YA, HONDA KAORI, KONDO YASUMITSU, SAITO TAMIO, KUBO TATSUHIKO, KANEDA MASATO, ONO HIROAKI, OSADA HIROYUKI, FUJII NOBUTAKA 化合物アレイを用いた新規MDM2/MDMX‐p53阻害剤の探索法の開発とその応用 化合物アレイを用いた新規MDM2/MDMX‐p53阻害剤の探索法の開発とその応用 化合物アレイを用いた新規MDM2/MDMX‐p53阻害剤の探索法の開発とその応用 メディシナルケミストリーシンポジウム講演要旨集, 31st, 120 メディシナルケミストリーシンポジウム講演要旨集, 31st, 120 メディシナルケミストリーシンポジウム講演要旨集, 31st, 120 2013/11/01 Japanese Disclose to all
SAKAI YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 坂井由葵, 大石真也, 藤井信孝, 大野浩章 SAKAI YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いたベンゾフランによる分子内ヒドロアリール化反応の検討 金触媒を用いたベンゾフランによる分子内ヒドロアリール化反応の検討 金触媒を用いたベンゾフランによる分子内ヒドロアリール化反応の検討 反応と合成の進歩シンポジウム講演要旨集, 39th, 67 反応と合成の進歩シンポジウム講演要旨集, 39th, 67 反応と合成の進歩シンポジウム講演要旨集, 39th, 67 2013/10/15 Japanese Disclose to all
ONO HIROAKI, YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA 大野浩章, 吉光佑二, 井貫晋輔, 大石真也, 藤井信孝 ONO HIROAKI, YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA パラジウム触媒を用いた中員環形成反応によるLaurencia族環状エーテルの構築:Laurendecumallene Bの合成研究 パラジウム触媒を用いた中員環形成反応によるLaurencia族環状エーテルの構築:Laurendecumallene Bの合成研究 パラジウム触媒を用いた中員環形成反応によるLaurencia族環状エーテルの構築:Laurendecumallene Bの合成研究 反応と合成の進歩シンポジウム講演要旨集, 39th, 5 反応と合成の進歩シンポジウム講演要旨集, 39th, 5 反応と合成の進歩シンポジウム講演要旨集, 39th, 5 2013/10/15 Japanese Disclose to all
IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 岩田顕, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒による連続環化反応を用いた四環性スピロインドール類の合成 パラジウム触媒による連続環化反応を用いた四環性スピロインドール類の合成 パラジウム触媒による連続環化反応を用いた四環性スピロインドール類の合成 反応と合成の進歩シンポジウム講演要旨集, 39th, 20 反応と合成の進歩シンポジウム講演要旨集, 39th, 20 反応と合成の進歩シンポジウム講演要旨集, 39th, 20 2013/10/15 Japanese Disclose to all
NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた共役ジインの多連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの多連続環化反応による縮環インドールの一挙合成 金触媒を用いた共役ジインの多連続環化反応による縮環インドールの一挙合成 反応と合成の進歩シンポジウム講演要旨集, 39th, 21 反応と合成の進歩シンポジウム講演要旨集, 39th, 21 反応と合成の進歩シンポジウム講演要旨集, 39th, 21 2013/10/15 Japanese Disclose to all
ONO HIROAKI, SUZUKI YAMATO, HOU ZENGYE, KURE TATSUHIDE, NAKANISHI ISAO, HIRASAWA AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA 大野浩章, 鈴木大和, HOU Zengye, 呉竜英, 仲西功, 平澤明, 大石真也, 藤井信孝 ONO HIROAKI, SUZUKI YAMATO, HOU ZENGYE, KURE TATSUHIDE, NAKANISHI ISAO, HIRASAWA AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA 金触媒を用いた三成分環化反応によるジヒドロピラゾールの合成とCK2阻害剤開発への応用 金触媒を用いた三成分環化反応によるジヒドロピラゾールの合成とCK2阻害剤開発への応用 金触媒を用いた三成分環化反応によるジヒドロピラゾールの合成とCK2阻害剤開発への応用 複素環化学討論会講演要旨集, 43rd, 353-354 複素環化学討論会講演要旨集, 43rd, 353-354 複素環化学討論会講演要旨集, 43rd, 353-354 2013/10/01 Japanese Disclose to all
MINAMIGUCHI DAIKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 南口大樹, 大石真也, 藤井信孝, 大野浩章 MINAMIGUCHI DAIKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI NK3Rアンタゴニストの多様性指向型合成法に関する検討 NK3Rアンタゴニストの多様性指向型合成法に関する検討 NK3Rアンタゴニストの多様性指向型合成法に関する検討 有機合成化学セミナー講演予稿集, 30th, 101 有機合成化学セミナー講演予稿集, 30th, 101 有機合成化学セミナー講演予稿集, 30th, 101 2013/09/17 Japanese Disclose to all
ITO DAISUKE, NAKATSUKASA KEISUKE, WAKABAYASHI YOSHIHIRO, YAMAMURA TAKASHI, OKAMURA HIROAKI, OISHI SHIN'YA, NOGUCHI TARO, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 伊藤太祐, 中務桂佑, 若林嘉浩, 山村崇, 岡村裕昭, 大石真也, 野口太朗, 藤井信孝, 上野山賀久, 束村博子, 前多敬一郎, 松田二子, 大蔵聡 ITO DAISUKE, NAKATSUKASA KEISUKE, WAKABAYASHI YOSHIHIRO, YAMAMURA TAKASHI, OKAMURA HIROAKI, OISHI SHIN'YA, NOGUCHI TARO, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 新規κオピオイド受容体拮抗剤の末梢投与がシバヤギGnRHパルスジェネレーター活動におよぼす効果 新規κオピオイド受容体拮抗剤の末梢投与がシバヤギGnRHパルスジェネレーター活動におよぼす効果 新規κオピオイド受容体拮抗剤の末梢投与がシバヤギGnRHパルスジェネレーター活動におよぼす効果 J Reprod Dev, 59, Suppl Japanese Issue, J103 J Reprod Dev, 59, Suppl Japanese Issue, J103 J Reprod Dev, 59, Suppl Japanese Issue, J103 2013/08/20 Japanese Disclose to all
NAMBA YOSUKE, HASSANEEN AHMED SAAD AHMED, KATO MASAO, ITO DAISUKE, OKUDA YUDAI, SUETOMI YUTA, SASAKI TAKUYA, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 難波陽介, HASSANEEN Ahmed Saad Ahmed, 加藤雅大, 伊藤太祐, 奥田雄大, 末富祐太, 佐々木拓弥, 説田章平, 大石真也, 藤井信孝, 上野山賀久, 束村博子, 前多敬一郎, 松田二子, 大蔵聡 NAMBA YOSUKE, HASSANEEN AHMED SAAD AHMED, KATO MASAO, ITO DAISUKE, OKUDA YUDAI, SUETOMI YUTA, SASAKI TAKUYA, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 卵胞期のウシにおけるキスペプチン末梢投与が性腺刺激ホルモン分泌,発情行動および排卵におよぼす効果の検討 卵胞期のウシにおけるキスペプチン末梢投与が性腺刺激ホルモン分泌,発情行動および排卵におよぼす効果の検討 卵胞期のウシにおけるキスペプチン末梢投与が性腺刺激ホルモン分泌,発情行動および排卵におよぼす効果の検討 J Reprod Dev, 59, Suppl Japanese Issue, J126 J Reprod Dev, 59, Suppl Japanese Issue, J126 J Reprod Dev, 59, Suppl Japanese Issue, J126 2013/08/20 Japanese Disclose to all
KAWABATA HIROSHI, UCHIYAMA TATSUKI, SAKAMOTO SOICHIRO, KANDA JUN'YA, OISHI SHIN'YA, FUJII NOBUTAKA, TOMOSUGI NAOHISA, TAKAORI AKIFUMI 川端浩, 内山達樹, 坂本宗一郎, 諫田淳也, 大石真也, 藤井信孝, 友杉直久, 高折晃史 KAWABATA HIROSHI, UCHIYAMA TATSUKI, SAKAMOTO SOICHIRO, KANDA JUN'YA, OISHI SHIN'YA, FUJII NOBUTAKA, TOMOSUGI NAOHISA, TAKAORI AKIFUMI ヘプシジン・プロモーターのバイオアッセイ ヘプシジン・プロモーターのバイオアッセイ ヘプシジン・プロモーターのバイオアッセイ 日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 37th, 39 日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 37th, 39 日本鉄バイオサイエンス学会学術集会プログラム・抄録集, 37th, 39 2013/08 Japanese Disclose to all
TAKENAGA MITSUKO, TAKEUCHI TOMOKI, TOKURA YUKIE, HAMAGUCHI AKEMI, YAMAMOTO YUKI, OTA YUKI, ASAI DAISUKE, OISHI SHIN'YA, NAKASHIMA HIDEKI, FUJII NOBUTAKA 武永美津子, 竹内智起, 都倉享恵, 濱口明美, 山本有貴, 太田有紀, 淺井大輔, 大石真也, 中島秀喜, 藤井信孝 TAKENAGA MITSUKO, TAKEUCHI TOMOKI, TOKURA YUKIE, HAMAGUCHI AKEMI, YAMAMOTO YUKI, OTA YUKI, ASAI DAISUKE, OISHI SHIN'YA, NAKASHIMA HIDEKI, FUJII NOBUTAKA 新規合成KSP阻害剤の抗腫瘍効果に関する研究 新規合成KSP阻害剤の抗腫瘍効果に関する研究 新規合成KSP阻害剤の抗腫瘍効果に関する研究 日本DDS学会学術集会プログラム予稿集, 29th, 170 日本DDS学会学術集会プログラム予稿集, 29th, 170 日本DDS学会学術集会プログラム予稿集, 29th, 170 2013/06/05 Japanese Disclose to all
TAKEUCHI TOMOOKI, OISHI SHIN'YA, KANEDA MASAHITO, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA 竹内智起, 大石真也, 金田雅仁, 大野浩章, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOOKI, OISHI SHIN'YA, KANEDA MASAHITO, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA キネシンモータータンパク質KSP阻害剤の創製研究―連続縮環型分子の変換による溶解性改善― キネシンモータータンパク質KSP阻害剤の創製研究―連続縮環型分子の変換による溶解性改善― キネシンモータータンパク質KSP阻害剤の創製研究―連続縮環型分子の変換による溶解性改善― 次世代を担う有機化学シンポジウム講演要旨集, 11th, 26-27 次世代を担う有機化学シンポジウム講演要旨集, 11th, 26-27 次世代を担う有機化学シンポジウム講演要旨集, 11th, 26-27 2013/05/24 Japanese Disclose to all
ZENDA MIYU, YASUI HIROYUKI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI 全田未悠, 安井裕之, 大石真也, 藤井信孝, 小出隆規 ZENDA MIYU, YASUI HIROYUKI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI シスプラチン誘導体のコラーゲン産生阻害能とそのメカニズム シスプラチン誘導体のコラーゲン産生阻害能とそのメカニズム シスプラチン誘導体のコラーゲン産生阻害能とそのメカニズム 日本化学会講演予稿集, 93rd, 3, 961 日本化学会講演予稿集, 93rd, 3, 961 日本化学会講演予稿集, 93rd, 3, 961 2013/03/08 Japanese Disclose to all
IWATA KEN, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 岩田顕, 大石真也, 藤井信孝, 大野浩章 IWATA KEN, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒による連続反応を用いたスピロインドール類の合成 パラジウム触媒による連続反応を用いたスピロインドール類の合成 パラジウム触媒による連続反応を用いたスピロインドール類の合成 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.30L-PM29S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.30L-PM29S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.30L-PM29S 2013 Japanese Disclose to all
KOBAYASHI YUKA, OISHI SHIN'YA, KOBAYASHI KAZUYA, ONO HIROAKI, TSUTSUMI HIROKO, HATA YOJI, FUJII NOBUTAKA 小林由佳, 大石真也, 小林数也, 大野浩章, 堤浩子, 秦洋二, 藤井信孝 KOBAYASHI YUKA, OISHI SHIN'YA, KOBAYASHI KAZUYA, ONO HIROAKI, TSUTSUMI HIROKO, HATA YOJI, FUJII NOBUTAKA デフェリフェリクリシン誘導体の合成と構造機能相関研究への応用 デフェリフェリクリシン誘導体の合成と構造機能相関研究への応用 デフェリフェリクリシン誘導体の合成と構造機能相関研究への応用 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.28M-PM21S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.28M-PM21S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.28M-PM21S 2013 Japanese Disclose to all
KAWAGUCHI YOSHIMASA, TANAKA GEN, NAKASE IKUHIKO, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMURA KAZUYA, MATSUOKA MASAO, FUTAKI SHIRO 川口祥正, 田中弦, 中瀬生彦, 大石真也, 藤井信孝, 志村和也, 松岡雅雄, 二木史朗 KAWAGUCHI YOSHIMASA, TANAKA GEN, NAKASE IKUHIKO, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMURA KAZUYA, MATSUOKA MASAO, FUTAKI SHIRO CXCR4によるマクロピノサイトーシスの誘導とHIV‐1感染 CXCR4によるマクロピノサイトーシスの誘導とHIV‐1感染 CXCR4によるマクロピノサイトーシスの誘導とHIV‐1感染 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM08S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM08S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM08S 2013 Japanese Disclose to all
NOGUCHI TARO, OISHI SHIN'YA, KUBO TATSUHIKO, ONO HIROAKI, KONDO YASUMITSU, SAITO TAMIO, OSADA HIROYUKI, FUJII NOBUTAKA 野口太朗, 大石真也, 久保達彦, 大野浩章, 近藤恭光, 斎藤臣雄, 長田裕之, 藤井信孝 NOGUCHI TARO, OISHI SHIN'YA, KUBO TATSUHIKO, ONO HIROAKI, KONDO YASUMITSU, SAITO TAMIO, OSADA HIROYUKI, FUJII NOBUTAKA 化合物アレイを用いたMDM2/MDMX‐P53阻害剤の探索法の開発 化合物アレイを用いたMDM2/MDMX‐P53阻害剤の探索法の開発 化合物アレイを用いたMDM2/MDMX‐P53阻害剤の探索法の開発 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM06S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM06S 日本薬学会年会要旨集(CD-ROM), 133rd, ROMBUNNO.29K-PM06S 2013 Japanese Disclose to all
MATSUYAMA SHUICHI, OKURA SATOSHI, OISHI SHIN'YA, KIMURA KOJI 松山秀一, 大蔵聡, 大石真也, 木村康二 MATSUYAMA SHUICHI, OKURA SATOSHI, OISHI SHIN'YA, KIMURA KOJI ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の単回末梢投与が性腺刺激ホルモン分泌および卵巣機能に及ぼす影響 ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の単回末梢投与が性腺刺激ホルモン分泌および卵巣機能に及ぼす影響 ウシ過剰排卵処置時におけるウシ型キスペプチン‐10の単回末梢投与が性腺刺激ホルモン分泌および卵巣機能に及ぼす影響 東日本家畜受精卵移植技術研究会大会資料, 29th, 39 東日本家畜受精卵移植技術研究会大会資料, 29th, 39 東日本家畜受精卵移植技術研究会大会資料, 29th, 39 2013 Japanese Disclose to all
SHIMURA KAZUYA, MIZUHARA TSUKASA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 志村和也, 水原司, 大石真也, 藤井信孝, 松岡雅雄 SHIMURA KAZUYA, MIZUHARA TSUKASA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 広範なスペクトルを有する新規抗HIV薬の同定とその開発 広範なスペクトルを有する新規抗HIV薬の同定とその開発 広範なスペクトルを有する新規抗HIV薬の同定とその開発 日本エイズ学会誌, 14, 4, 319 日本エイズ学会誌, 14, 4, 319 日本エイズ学会誌, 14, 4, 319 2012/11/20 Japanese Disclose to all
TANAKA GEN, NAKASE IKUHIKO, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMURA KAZUYA, MATSUOKA MASAO, FUTAKI SHIRO 田中弦, 中瀬生彦, 大石真也, 藤井信孝, 志村和也, 松岡雅雄, 二木史朗 TANAKA GEN, NAKASE IKUHIKO, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMURA KAZUYA, MATSUOKA MASAO, FUTAKI SHIRO マクロピノサイトーシス誘導受容体としてのCXCR4 マクロピノサイトーシス誘導受容体としてのCXCR4 マクロピノサイトーシス誘導受容体としてのCXCR4 生体膜と薬物の相互作用シンポジウム講演要旨集, 34th, 156-157 生体膜と薬物の相互作用シンポジウム講演要旨集, 34th, 156-157 生体膜と薬物の相互作用シンポジウム講演要旨集, 34th, 156-157 2012/11/15 Japanese Disclose to all
GO RYUEI, KO ZOYO, KINOSHITA TAKAYOSHI, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, NAKAMURA SHIN'YA, ONO HIROAKI, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NAKANISHI ISAO 呉竜英, 候増よう, 木下誉富, 武井義則, 安江美里, 三須良介, 鈴木大和, 中村真也, 大野浩章, 村田克美, 北浦和夫, 平澤明, 大石真也, 藤井信孝, 仲西功 GO RYUEI, KO ZOYO, KINOSHITA TAKAYOSHI, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, NAKAMURA SHIN'YA, ONO HIROAKI, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NAKANISHI ISAO 非経験的フラグメント分子軌道法を活用した高活性Protein Kinase CK2阻害剤の設計 非経験的フラグメント分子軌道法を活用した高活性Protein Kinase CK2阻害剤の設計 非経験的フラグメント分子軌道法を活用した高活性Protein Kinase CK2阻害剤の設計 構造活性相関シンポジウム講演要旨集, 40th, 30-33 構造活性相関シンポジウム講演要旨集, 40th, 30-33 構造活性相関シンポジウム講演要旨集, 40th, 30-33 2012/11/12 Japanese Disclose to all
NAOE SAORI, SUZUKI YAMATO, OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, HOU ZENGYE, KURE TATSUHIDE, NAKANISHI ISAO, ONO HIROAKI, HIRASAWA AKIRA, FUJII NOBUTAKA 直江紗織, 鈴木大和, 大石真也, 武井義則, 安江美里, 三須良介, HOU Zengye, 呉竜英, 仲西功, 大野浩章, 平澤明, 藤井信孝 NAOE SAORI, SUZUKI YAMATO, OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, HOU ZENGYE, KURE TATSUHIDE, NAKANISHI ISAO, ONO HIROAKI, HIRASAWA AKIRA, FUJII NOBUTAKA 縮環型含窒素複素環の多様性指向型合成反応の開発とCK2阻害剤の構造活性相関研究への応用 縮環型含窒素複素環の多様性指向型合成反応の開発とCK2阻害剤の構造活性相関研究への応用 縮環型含窒素複素環の多様性指向型合成反応の開発とCK2阻害剤の構造活性相関研究への応用 メディシナルケミストリーシンポジウム講演要旨集, 30th, 66 メディシナルケミストリーシンポジウム講演要旨集, 30th, 66 メディシナルケミストリーシンポジウム講演要旨集, 30th, 66 2012/11/01 Japanese Disclose to all
KATO FUMIHIRO, KAWAGISHI TAKAHIRO, HYUGA RYOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, MIURA TOMOYUKI, KOBAYASHI TAKESHI, IGARASHI TATSUHIKO 加藤文博, 川岸崇裕, 日向亮輔, 大石真也, 藤井信孝, 三浦智行, 小林剛, 五十嵐樹彦 KATO FUMIHIRO, KAWAGISHI TAKAHIRO, HYUGA RYOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, MIURA TOMOYUKI, KOBAYASHI TAKESHI, IGARASHI TATSUHIKO 抗デングウイルス活性を有する化合物の探索および作用機序の解析 抗デングウイルス活性を有する化合物の探索および作用機序の解析 抗デングウイルス活性を有する化合物の探索および作用機序の解析 日本ウイルス学会学術集会プログラム・抄録集, 60th, 364 日本ウイルス学会学術集会プログラム・抄録集, 60th, 364 日本ウイルス学会学術集会プログラム・抄録集, 60th, 364 2012/10/31 Japanese Disclose to all
YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 吉光佑二, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒によるプロパルギル化合物の中員環形成反応を利用したLaurendecumallene Bの全合成研究 パラジウム触媒によるプロパルギル化合物の中員環形成反応を利用したLaurendecumallene Bの全合成研究 パラジウム触媒によるプロパルギル化合物の中員環形成反応を利用したLaurendecumallene Bの全合成研究 反応と合成の進歩シンポジウム講演要旨集, 38th, 96-97 反応と合成の進歩シンポジウム講演要旨集, 38th, 96-97 反応と合成の進歩シンポジウム講演要旨集, 38th, 96-97 2012/10/15 Japanese Disclose to all
CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI (-)‐Quinocarcinの全合成 (-)‐Quinocarcinの全合成 (-)‐Quinocarcinの全合成 反応と合成の進歩シンポジウム講演要旨集, 38th, 182-183 反応と合成の進歩シンポジウム講演要旨集, 38th, 182-183 反応と合成の進歩シンポジウム講演要旨集, 38th, 182-183 2012/10/15 Japanese Disclose to all
MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 宮垣潤, 吉光佑二, 大石真也, 藤井信孝, 大野浩章 MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Jaspine Bおよびその誘導体の多様性指向型合成研究 Jaspine Bおよびその誘導体の多様性指向型合成研究 Jaspine Bおよびその誘導体の多様性指向型合成研究 複素環化学討論会講演要旨集, 42nd, 195-196 複素環化学討論会講演要旨集, 42nd, 195-196 複素環化学討論会講演要旨集, 42nd, 195-196 2012/09/30 Japanese Disclose to all
NAOE SAORI, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 鈴木大和, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 複素環化学討論会講演要旨集, 42nd, 153-154 複素環化学討論会講演要旨集, 42nd, 153-154 複素環化学討論会講演要旨集, 42nd, 153-154 2012/09/30 Japanese Disclose to all
HOU ZENGYE, OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, NAKANISHI ISAO, NAKAMURA SHIN'YA, KURE TATSUHIDE, KINOSHITA TAKAYOSHI, FUJII NOBUTAKA HOU Zengye, 大石真也, 武井義則, 安江美里, 三須良介, 鈴木大和, 村田克美, 北浦和夫, 平澤明, 辻本豪三, 大野浩章, 仲西功, 中村真也, 呉竜英, 木下誉富, 藤井信孝 HOU ZENGYE, OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, NAKANISHI ISAO, NAKAMURA SHIN'YA, KURE TATSUHIDE, KINOSHITA TAKAYOSHI, FUJII NOBUTAKA フェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発 フェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発 フェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発 複素環化学討論会講演要旨集, 42nd, 245-246 複素環化学討論会講演要旨集, 42nd, 245-246 複素環化学討論会講演要旨集, 42nd, 245-246 2012/09/30 Japanese Disclose to all
MIZUHARA TSUKASA, OISHI SHIN'YA, ONO HIROAKI, SHIMURA KAZUYA, MATSUOKA MASAO, FUJII NOBUTAKA 水原司, 大石真也, 大野浩章, 志村和也, 松岡雅雄, 藤井信孝 MIZUHARA TSUKASA, OISHI SHIN'YA, ONO HIROAKI, SHIMURA KAZUYA, MATSUOKA MASAO, FUJII NOBUTAKA ピリミドベンゾチアジン誘導体の合成法の開発と抗HIV剤の構造活性相関研究への応用 ピリミドベンゾチアジン誘導体の合成法の開発と抗HIV剤の構造活性相関研究への応用 ピリミドベンゾチアジン誘導体の合成法の開発と抗HIV剤の構造活性相関研究への応用 複素環化学討論会講演要旨集, 42nd, 51-52 複素環化学討論会講演要旨集, 42nd, 51-52 複素環化学討論会講演要旨集, 42nd, 51-52 2012/09/30 Japanese Disclose to all
NAMBA YOSUKE, NAKATSUKASA KEISUKE, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 難波陽介, 中務桂佑, 説田章平, 大石真也, 藤井信孝, 上野山賀久, 束村博子, 前多敬一郎, 松田二子, 大蔵聡 NAMBA YOSUKE, NAKATSUKASA KEISUKE, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI キスペプチンおよびGnRH末梢投与がウシの卵巣活動におよぼす効果の比較 キスペプチンおよびGnRH末梢投与がウシの卵巣活動におよぼす効果の比較 キスペプチンおよびGnRH末梢投与がウシの卵巣活動におよぼす効果の比較 日本内分泌学会雑誌, 88, 2, 747 日本内分泌学会雑誌, 88, 2, 747 日本内分泌学会雑誌, 88, 2, 747 2012/09/20 Japanese Disclose to all
SAKAI YUKI, CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 坂井由葵, 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 SAKAI YUKI, CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI ルイス酸によるジヒドロベンゾフランの環交換反応を用いた(-)‐Quinocarcinamideの形成合成 ルイス酸によるジヒドロベンゾフランの環交換反応を用いた(-)‐Quinocarcinamideの形成合成 ルイス酸によるジヒドロベンゾフランの環交換反応を用いた(-)‐Quinocarcinamideの形成合成 有機合成化学セミナー講演予稿集, 29th, 153 有機合成化学セミナー講演予稿集, 29th, 153 有機合成化学セミナー講演予稿集, 29th, 153 2012/09/05 Japanese Disclose to all
SEKIYA ATSUSHI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI 関谷敦志, 大石真也, 藤井信孝, 小出隆規 SEKIYA ATSUSHI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI ヘパリン/ヘパラン硫酸(HS)阻害剤の新規探索法の開発 ヘパリン/ヘパラン硫酸(HS)阻害剤の新規探索法の開発 ヘパリン/ヘパラン硫酸(HS)阻害剤の新規探索法の開発 日本結合組織学会学術大会抄録集, 44th, 54 日本結合組織学会学術大会抄録集, 44th, 54 日本結合組織学会学術大会抄録集, 44th, 54 2012/06/01 Japanese Disclose to all
HOU Z., OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, FUJII NOBUTAKA, NAKANISHI ISAO, NAKAMURA SHIN'YA, KURE RYUEI, KINOSHITA TAKAYOSHI HOU Z., 大石真也, 武井義則, 安江美里, 三須良介, 鈴木大和, 村田克美, 北浦和夫, 平澤明, 辻本豪三, 大野浩章, 藤井信孝, 仲西功, 中村真也, 呉竜英, 木下誉富 HOU Z., OISHI SHIN'YA, TAKEI YOSHINORI, YASUE MISATO, MISU RYOSUKE, SUZUKI YAMATO, MURATA KATSUMI, KITAURA KAZUO, HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, FUJII NOBUTAKA, NAKANISHI ISAO, NAKAMURA SHIN'YA, KURE RYUEI, KINOSHITA TAKAYOSHI アザインドール骨格またはフェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発研究 アザインドール骨格またはフェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発研究 アザインドール骨格またはフェニルアゾール骨格を有する新規プロテインキナーゼCK2阻害剤の開発研究 次世代を担う有機化学シンポジウム講演要旨集, 10th, 50-51 次世代を担う有機化学シンポジウム講演要旨集, 10th, 50-51 次世代を担う有機化学シンポジウム講演要旨集, 10th, 50-51 2012/05/11 Japanese Disclose to all
NAMBA YOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI 難波陽介, 大石真也, 藤井信孝, 上野山賀久, 束村博子, 前多敬一郎, 松田二子, 大蔵聡 NAMBA YOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, MATSUDA NIKO, OKURA SATOSHI キスペプチンによる卵胞発育刺激作用 キスペプチンによる卵胞発育刺激作用 キスペプチンによる卵胞発育刺激作用 日本内分泌学会雑誌, 88, 1, 351 日本内分泌学会雑誌, 88, 1, 351 日本内分泌学会雑誌, 88, 1, 351 2012/04/01 Japanese Disclose to all
MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 宮垣潤, 吉光佑二, 大石真也, 藤井信孝, 大野浩章 MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Jaspine Bおよびその誘導体の多様性指向型合成 Jaspine Bおよびその誘導体の多様性指向型合成 Jaspine Bおよびその誘導体の多様性指向型合成 日本薬学会年会要旨集, 132nd, 2, 104 日本薬学会年会要旨集, 132nd, 2, 104 日本薬学会年会要旨集, 132nd, 2, 104 2012/03/05 Japanese Disclose to all
SEKIYA ATSUSHI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI 関谷敦志, 大石真也, 藤井信孝, 小出隆規 SEKIYA ATSUSHI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI コラーゲンの線維形成を利用した新規ヘパリン/ヘパラン硫酸阻害剤探索法の開発 コラーゲンの線維形成を利用した新規ヘパリン/ヘパラン硫酸阻害剤探索法の開発 コラーゲンの線維形成を利用した新規ヘパリン/ヘパラン硫酸阻害剤探索法の開発 日本薬学会年会要旨集, 132nd, 3, 121 日本薬学会年会要旨集, 132nd, 3, 121 日本薬学会年会要旨集, 132nd, 3, 121 2012/03/05 Japanese Disclose to all
MIZUSHIMA SHINGO, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 水嶋真吾, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 MIZUSHIMA SHINGO, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Pd触媒によるプロパルギル化合物の連続環化反応を利用した(+)‐Biotinの合成研究 Pd触媒によるプロパルギル化合物の連続環化反応を利用した(+)‐Biotinの合成研究 Pd触媒によるプロパルギル化合物の連続環化反応を利用した(+)‐Biotinの合成研究 日本薬学会年会要旨集, 132nd, 2, 112 日本薬学会年会要旨集, 132nd, 2, 112 日本薬学会年会要旨集, 132nd, 2, 112 2012/03/05 Japanese Disclose to all
ZENTA MIYU, YAMASAKI CHISATO, YASUI HIROYUKI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI 全田未悠, 山崎ちさと, 安井裕之, 大石真也, 藤井信孝, 小出隆規 ZENTA MIYU, YAMASAKI CHISATO, YASUI HIROYUKI, OISHI SHIN'YA, FUJII NOBUTAKA, KOIDE TAKAKI コラーゲンの細線維形成を阻害するプラチナ錯体の作用機構の解析 コラーゲンの細線維形成を阻害するプラチナ錯体の作用機構の解析 コラーゲンの細線維形成を阻害するプラチナ錯体の作用機構の解析 日本薬学会年会要旨集, 132nd, 2, 167 日本薬学会年会要旨集, 132nd, 2, 167 日本薬学会年会要旨集, 132nd, 2, 167 2012/03/05 Japanese Disclose to all
NAOE SAORI, SUZUKI YAMATO, HIRANO KIMIO, INABA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 鈴木大和, 平野公夫, 稲葉祐介, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, SUZUKI YAMATO, HIRANO KIMIO, INABA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた位置選択的なカスケード型分子間/分子内付加反応による縮合ベンゼン環の一挙構築法の開発 金触媒を用いた位置選択的なカスケード型分子間/分子内付加反応による縮合ベンゼン環の一挙構築法の開発 金触媒を用いた位置選択的なカスケード型分子間/分子内付加反応による縮合ベンゼン環の一挙構築法の開発 日本薬学会年会要旨集, 132nd, 2, 181 日本薬学会年会要旨集, 132nd, 2, 181 日本薬学会年会要旨集, 132nd, 2, 181 2012/03/05 Japanese Disclose to all
NAMIKAWA RYOTA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 並河亮太, 大石真也, 大野浩章, 藤井信孝 NAMIKAWA RYOTA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 抗腫瘍活性ペプチドcoibamide Aの標的同定プローブを指向した合成 抗腫瘍活性ペプチドcoibamide Aの標的同定プローブを指向した合成 抗腫瘍活性ペプチドcoibamide Aの標的同定プローブを指向した合成 日本薬学会年会要旨集, 132nd, 2, 159 日本薬学会年会要旨集, 132nd, 2, 159 日本薬学会年会要旨集, 132nd, 2, 159 2012/03/05 Japanese Disclose to all
KASAI SHOTA, SAKAI YUKI, TSUNEMATSU YUTA, HATTORI AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, KAKEYA HIDEAKI 笠井昭太, 酒井佑宜, 恒松雄太, 服部明, 大石真也, 藤井信孝, 西村慎一, 掛谷秀昭 KASAI SHOTA, SAKAI YUKI, TSUNEMATSU YUTA, HATTORI AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, KAKEYA HIDEAKI 新規TGF‐βシグナル伝達阻害剤tryptopeptin Aおよび分子プローブの合成研究 新規TGF‐βシグナル伝達阻害剤tryptopeptin Aおよび分子プローブの合成研究 新規TGF‐βシグナル伝達阻害剤tryptopeptin Aおよび分子プローブの合成研究 日本薬学会年会要旨集, 132nd, 2, 221 日本薬学会年会要旨集, 132nd, 2, 221 日本薬学会年会要旨集, 132nd, 2, 221 2012/03/05 Japanese Disclose to all
TAKEUCHI TOMOTATSU, OISHI SHIN'YA, FUJII NOBUTAKA 竹内智起, 大石真也, 藤井信孝 TAKEUCHI TOMOTATSU, OISHI SHIN'YA, FUJII NOBUTAKA ナノバイオ技術と最新創薬応用研究 第2章 ナノバイオ創薬におけるシード・リード化合物の創出と展開 1.ケミカルバイオロジー研究を基盤にした抗癌剤の創出:KSP阻害剤の創出 ナノバイオ技術と最新創薬応用研究 第2章 ナノバイオ創薬におけるシード・リード化合物の創出と展開 1.ケミカルバイオロジー研究を基盤にした抗癌剤の創出:KSP阻害剤の創出 ナノバイオ技術と最新創薬応用研究 第2章 ナノバイオ創薬におけるシード・リード化合物の創出と展開 1.ケミカルバイオロジー研究を基盤にした抗癌剤の創出:KSP阻害剤の創出 遺伝子医学MOOK, 20, 54-59,6 遺伝子医学MOOK, 20, 54-59,6 遺伝子医学MOOK, 20, 54-59,6 2012/01/31 Japanese Disclose to all
志村和也,水原司,大石真也,藤井信孝,松岡雅雄 志村和也,水原司,大石真也,藤井信孝,松岡雅雄 広範なスペクトルを有する新規HIV 薬の同定とその開発 広範なスペクトルを有する新規HIV 薬の同定とその開発 第26 回日本エイズ学会学術集会、慶應義塾大学日吉キャンパ ス(横浜) 、2012 年11 月24-26日 第26 回日本エイズ学会学術集会、慶應義塾大学日吉キャンパ ス(横浜) 、2012 年11 月24-26日 2012 Refereed Japanese Disclose to all
加藤文博,川岸崇裕,日向亮輔,大石真也,藤井信孝,三浦智行,小林剛,五十嵐樹彦 加藤文博,川岸崇裕,日向亮輔,大石真也,藤井信孝,三浦智行,小林剛,五十嵐樹彦 抗ダンプウイルス活性を有するかご物の探索および作用機序の解析 抗ダンプウイルス活性を有するかご物の探索および作用機序の解析 第60 回日本 ウイルス学会学術集会、大阪、2012 年11 月13 日 第60 回日本 ウイルス学会学術集会、大阪、2012 年11 月13 日 2012 Refereed Japanese Disclose to all
SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 志村和也, 大石真也, 藤井信孝, 松岡雅雄 SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO HIV‐1膜融合阻害剤に対する新規耐性メカニズムの解析 HIV‐1膜融合阻害剤に対する新規耐性メカニズムの解析 HIV‐1膜融合阻害剤に対する新規耐性メカニズムの解析 日本エイズ学会誌, 13, 4, 483 日本エイズ学会誌, 13, 4, 483 日本エイズ学会誌, 13, 4, 483 2011/11/20 Japanese Disclose to all
WATABE MASAHIRO, HASHIMOTO KOICHI, ABE YUSAKU, OHARA SHIN'ICHIRO, SATO AKISATO, KAWASAKI YUKIHIKO, KODAMA EIICHI, OISHI SHIN'YA, HOSOYA MITSUAKI 渡部真裕, 橋本浩一, 阿部優作, 大原信一郎, 佐藤晶論, 川崎幸彦, 児玉栄一, 大石真也, 細矢光亮 WATABE MASAHIRO, HASHIMOTO KOICHI, ABE YUSAKU, OHARA SHIN'ICHIRO, SATO AKISATO, KAWASAKI YUKIHIKO, KODAMA EIICHI, OISHI SHIN'YA, HOSOYA MITSUAKI 膜融合蛋白(F蛋白)を標的とした新規ペプチドによる亜急性硬化性全脳炎の新たな治療戦略 膜融合蛋白(F蛋白)を標的とした新規ペプチドによる亜急性硬化性全脳炎の新たな治療戦略 膜融合蛋白(F蛋白)を標的とした新規ペプチドによる亜急性硬化性全脳炎の新たな治療戦略 Neuroinfection, 16, 2, 152 Neuroinfection, 16, 2, 152 Neuroinfection, 16, 2, 152 2011/10/21 Japanese Disclose to all
KOBAYASHI KAZUYA, OISHI SHIN'YA, INOKUCHI ERIKO, HAYASHI RYOKO, TOMITA KENJI, KUBO TATSUHIKO, TANAHARA NORIKO, ONO HIROAKI, FUJII NOBUTAKA, YOSHIKAWA YASUSHI, FURUYA TOSHIO, SHIMURA KAZUYA, MATSUOKA MASAO 小林数也, 大石真也, 井ノ口恵利子, 林亮子, 富田健嗣, 久保達彦, 棚原憲子, 大野浩章, 藤井信孝, 吉川寧, 古谷利夫, 志村和也, 松岡雅雄 KOBAYASHI KAZUYA, OISHI SHIN'YA, INOKUCHI ERIKO, HAYASHI RYOKO, TOMITA KENJI, KUBO TATSUHIKO, TANAHARA NORIKO, ONO HIROAKI, FUJII NOBUTAKA, YOSHIKAWA YASUSHI, FURUYA TOSHIO, SHIMURA KAZUYA, MATSUOKA MASAO アルケン型及びアミジン型ペプチドイソスターの合成とCXCR4拮抗剤の構造活性相関研究への応用 アルケン型及びアミジン型ペプチドイソスターの合成とCXCR4拮抗剤の構造活性相関研究への応用 アルケン型及びアミジン型ペプチドイソスターの合成とCXCR4拮抗剤の構造活性相関研究への応用 反応と合成の進歩シンポジウム講演要旨集, 37th, 364-365 反応と合成の進歩シンポジウム講演要旨集, 37th, 364-365 反応と合成の進歩シンポジウム講演要旨集, 37th, 364-365 2011/10/14 Japanese Disclose to all
IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 岩田顕, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI リゼルグ酸および関連アルカロイドの不斉全合成 リゼルグ酸および関連アルカロイドの不斉全合成 リゼルグ酸および関連アルカロイドの不斉全合成 反応と合成の進歩シンポジウム講演要旨集, 37th, 314-315 反応と合成の進歩シンポジウム講演要旨集, 37th, 314-315 反応と合成の進歩シンポジウム講演要旨集, 37th, 314-315 2011/10/14 Japanese Disclose to all
SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 鈴木大和, 大石真也, 藤井信孝, 大野浩章 SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 金触媒による三成分環形成反応を用いた多置換ジヒドロピラゾールの効率的合成法の開発 反応と合成の進歩シンポジウム講演要旨集, 37th, 310-311 反応と合成の進歩シンポジウム講演要旨集, 37th, 310-311 反応と合成の進歩シンポジウム講演要旨集, 37th, 310-311 2011/10/14 Japanese Disclose to all
NAOE SAORI, HIRANO KIMIO, INABA YUSUKE, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 平野公夫, 稲葉祐介, 鈴木大和, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, HIRANO KIMIO, INABA YUSUKE, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いたアルキンに対する分子間求核付加‐環化反応によるナフタレン誘導体の合成 金触媒を用いたアルキンに対する分子間求核付加‐環化反応によるナフタレン誘導体の合成 金触媒を用いたアルキンに対する分子間求核付加‐環化反応によるナフタレン誘導体の合成 反応と合成の進歩シンポジウム講演要旨集, 37th, 318-319 反応と合成の進歩シンポジウム講演要旨集, 37th, 318-319 反応と合成の進歩シンポジウム講演要旨集, 37th, 318-319 2011/10/14 Japanese Disclose to all
ONO HIROAKI, HIRANO KIMIO, INABA YUSUKE, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA 大野浩章, 平野公夫, 稲葉祐介, 直江紗織, 大石真也, 藤井信孝 ONO HIROAKI, HIRANO KIMIO, INABA YUSUKE, NAOE SAORI, OISHI SHIN'YA, FUJII NOBUTAKA 金触媒によるアルキンのヒドロアリール化を用いた多連続環化反応の開発 金触媒によるアルキンのヒドロアリール化を用いた多連続環化反応の開発 金触媒によるアルキンのヒドロアリール化を用いた多連続環化反応の開発 複素環化学討論会講演要旨集, 41st, 13-14 複素環化学討論会講演要旨集, 41st, 13-14 複素環化学討論会講演要旨集, 41st, 13-14 2011/09/30 Japanese Disclose to all
CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 天然有機化合物討論会講演要旨集, 53rd, 499-504 天然有機化合物討論会講演要旨集, 53rd, 499-504 天然有機化合物討論会講演要旨集, 53rd, 499-504 2011/09/02 Japanese Disclose to all
NAOE SAORI, HIRANO KIMIO, INABA YUSUKE, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 直江紗織, 平野公夫, 稲葉祐介, 鈴木大和, 大石真也, 藤井信孝, 大野浩章 NAOE SAORI, HIRANO KIMIO, INABA YUSUKE, SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いたアルキンのヒドロアリール化反応を基盤とする連続環化反応の開発 金触媒を用いたアルキンのヒドロアリール化反応を基盤とする連続環化反応の開発 金触媒を用いたアルキンのヒドロアリール化反応を基盤とする連続環化反応の開発 有機合成化学セミナー講演予稿集, 28th, 92 有機合成化学セミナー講演予稿集, 28th, 92 有機合成化学セミナー講演予稿集, 28th, 92 2011/08/31 Japanese Disclose to all
MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 宮垣潤, 吉光佑二, 大石真也, 藤井信孝, 大野浩章 MIYAGAKI JUN, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Jaspine Bおよびその誘導体の多様性指向型合成 Jaspine Bおよびその誘導体の多様性指向型合成 Jaspine Bおよびその誘導体の多様性指向型合成 有機合成化学セミナー講演予稿集, 28th, 91 有機合成化学セミナー講演予稿集, 28th, 91 有機合成化学セミナー講演予稿集, 28th, 91 2011/08/31 Japanese Disclose to all
NAMBA YOSUKE, NAKATSUKASA KEISUKE, SETSUDA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, WAKABAYASHI YOSHIHIRO, OKAMURA HIROAKI, MATSUDA NIKO, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, OKURA SATOSHI 難波陽介, 中務桂佑, 説田章平, 大石真也, 藤井信孝, 若林嘉浩, 岡村裕昭, 松田二子, 上野山賀久, 束村博子, 前多敬一郎, 大蔵聡 NAMBA YOSUKE, NAKATSUKASA KEISUKE, SETSUDA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, WAKABAYASHI YOSHIHIRO, OKAMURA HIROAKI, MATSUDA NIKO, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, OKURA SATOSHI 黒毛和種成熟雌ウシにおいてキスペプチン末梢投与は黄体形成ホルモン分泌および卵胞発育を刺激する 黒毛和種成熟雌ウシにおいてキスペプチン末梢投与は黄体形成ホルモン分泌および卵胞発育を刺激する 黒毛和種成熟雌ウシにおいてキスペプチン末梢投与は黄体形成ホルモン分泌および卵胞発育を刺激する J Reprod Dev, 57, Suppl Japanese Issue, J143 J Reprod Dev, 57, Suppl Japanese Issue, J143 J Reprod Dev, 57, Suppl Japanese Issue, J143 2011/08/20 Japanese Disclose to all
YOSHIMITSU YUJI, OISHI SHIN'YA, MIYAGAKI JUN, INUKI SHINSUKE, FUJII NOBUTAKA, ONO HIROAKI 吉光佑二, 大石真也, 宮垣潤, 井貫晋輔, 藤井信孝, 大野浩章 YOSHIMITSU YUJI, OISHI SHIN'YA, MIYAGAKI JUN, INUKI SHINSUKE, FUJII NOBUTAKA, ONO HIROAKI Jaspine Bおよびその誘導体の立体分岐合成と構造活性相関研究 Jaspine Bおよびその誘導体の立体分岐合成と構造活性相関研究 Jaspine Bおよびその誘導体の立体分岐合成と構造活性相関研究 次世代を担う有機化学シンポジウム講演要旨集, 9th, 54-55 次世代を担う有機化学シンポジウム講演要旨集, 9th, 54-55 次世代を担う有機化学シンポジウム講演要旨集, 9th, 54-55 2011/05/22 Japanese Disclose to all
ZENDA MIYU, OISHI SHIN'YA, YASUI HIROYUKI, YAMAZAKI CHISATO, KOIDE TAKAKI 全田未悠, 大石真也, 安井裕之, 山崎ちさと, 小出隆規 ZENDA MIYU, OISHI SHIN'YA, YASUI HIROYUKI, YAMAZAKI CHISATO, KOIDE TAKAKI コラーゲン線維形成を阻害するプラチナ錯体の発見とその作用機構の解析 コラーゲン線維形成を阻害するプラチナ錯体の発見とその作用機構の解析 コラーゲン線維形成を阻害するプラチナ錯体の発見とその作用機構の解析 日本結合組織学会学術大会抄録集, 43rd, 67 日本結合組織学会学術大会抄録集, 43rd, 67 日本結合組織学会学術大会抄録集, 43rd, 67 2011/05/18 Japanese Disclose to all
NISHIZAWA KOJI, NISHIYAMA HIROYUKI, TEI MORIYASU, TEI MORIYASU, OISHI SHIN'YA, SAITO RYOICHI, MATSUI YOSHIYUKI, OGAWA OSAMU 西澤恒二, 西山博之, 丁森泰, 丁森泰, 大石真也, 齊藤亮一, 松井喜之, 小川修 NISHIZAWA KOJI, NISHIYAMA HIROYUKI, TEI MORIYASU, TEI MORIYASU, OISHI SHIN'YA, SAITO RYOICHI, MATSUI YOSHIYUKI, OGAWA OSAMU 膀胱癌に対する新規Eg5阻害剤(S)‐methoxy‐trityl‐L‐cysteinの抗腫瘍効果 膀胱癌に対する新規Eg5阻害剤(S)‐methoxy‐trityl‐L‐cysteinの抗腫瘍効果 膀胱癌に対する新規Eg5阻害剤(S)‐methoxy‐trityl‐L‐cysteinの抗腫瘍効果 日本泌尿器科学会雑誌, 102, 2, 533 日本泌尿器科学会雑誌, 102, 2, 533 日本泌尿器科学会雑誌, 102, 2, 533 2011/03/20 Japanese Disclose to all
INABA YUSUKE, HIRANO KIMIO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 稲葉祐介, 平野公夫, 大石真也, 藤井信孝, 大野浩章 INABA YUSUKE, HIRANO KIMIO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いたアニリン誘導体の連続型分子内ヒドロアミノ化―ヒドロアリール化反応による高度縮環型カルバゾール誘導体の合成 金触媒を用いたアニリン誘導体の連続型分子内ヒドロアミノ化―ヒドロアリール化反応による高度縮環型カルバゾール誘導体の合成 金触媒を用いたアニリン誘導体の連続型分子内ヒドロアミノ化―ヒドロアリール化反応による高度縮環型カルバゾール誘導体の合成 日本薬学会年会要旨集, 131st, 2, 124 日本薬学会年会要旨集, 131st, 2, 124 日本薬学会年会要旨集, 131st, 2, 124 2011/03/05 Japanese Disclose to all
IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 岩田顕, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 IWATA AKIRA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI (+)‐リゼルグ酸の不斉全合成研究 (+)‐リゼルグ酸の不斉全合成研究 (+)‐リゼルグ酸の不斉全合成研究 日本薬学会年会要旨集, 131st, 2, 101 日本薬学会年会要旨集, 131st, 2, 101 日本薬学会年会要旨集, 131st, 2, 101 2011/03/05 Japanese Disclose to all
TOKIMIZU YUSUKE, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 時水勇輔, 太田悠介, 大石真也, 藤井信孝, 大野浩章 TOKIMIZU YUSUKE, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 日本薬学会年会要旨集, 131st, 2, 125 日本薬学会年会要旨集, 131st, 2, 125 日本薬学会年会要旨集, 131st, 2, 125 2011/03/05 Japanese Disclose to all
NAMIKAWA RYOTA, OISHI SHIN'YA, INOKUCHI ERIKO, ONO HIROAKI, FUJII NOBUTAKA 並河亮太, 大石真也, 井ノ口恵利子, 大野浩章, 藤井信孝 NAMIKAWA RYOTA, OISHI SHIN'YA, INOKUCHI ERIKO, ONO HIROAKI, FUJII NOBUTAKA Coibamide Aの合成研究 Coibamide Aの合成研究 Coibamide Aの合成研究 日本薬学会年会要旨集, 131st, 2, 120 日本薬学会年会要旨集, 131st, 2, 120 日本薬学会年会要旨集, 131st, 2, 120 2011/03/05 Japanese Disclose to all
KOBAYASHI KAZUYA, HAYASHI RYOKO, OISHI SHIN'YA, KUBO TATSUHIKO, ONO HIROAKI, FUJII NOBUTAKA 小林数也, 林亮子, 大石真也, 久保達彦, 大野浩章, 藤井信孝 KOBAYASHI KAZUYA, HAYASHI RYOKO, OISHI SHIN'YA, KUBO TATSUHIKO, ONO HIROAKI, FUJII NOBUTAKA アルケン型ジペプチドイソスターの合成とCXCR4拮抗剤FC131の構造活性相関研究への応用 アルケン型ジペプチドイソスターの合成とCXCR4拮抗剤FC131の構造活性相関研究への応用 アルケン型ジペプチドイソスターの合成とCXCR4拮抗剤FC131の構造活性相関研究への応用 日本薬学会年会要旨集, 131st, 2, 94 日本薬学会年会要旨集, 131st, 2, 94 日本薬学会年会要旨集, 131st, 2, 94 2011/03/05 Japanese Disclose to all
TAKEUCHI TOMOTATSU, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA 竹内智起, 大石真也, 渡部敏明, 大野浩章, 浅田直也, 北浦和夫, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOTATSU, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 日本薬学会年会要旨集, 131st, 2, 132 日本薬学会年会要旨集, 131st, 2, 132 日本薬学会年会要旨集, 131st, 2, 132 2011/03/05 Japanese Disclose to all
CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 金触媒を用いた分子内ヒドロアミノ化反応を基盤としたQuinocarcinの合成研究 日本薬学会年会要旨集, 131st, 2, 101 日本薬学会年会要旨集, 131st, 2, 101 日本薬学会年会要旨集, 131st, 2, 101 2011/03/05 Japanese Disclose to all
ZENDA MIYU, YAMAZAKI CHISATO, OISHI SHIN'YA, YASUI HIROYUKI, KOIDE TAKAKI 全田未悠, 山崎ちさと, 大石真也, 安井裕之, 小出隆規 ZENDA MIYU, YAMAZAKI CHISATO, OISHI SHIN'YA, YASUI HIROYUKI, KOIDE TAKAKI シスプラチン誘導体はコラーゲンのin vitro線維化を阻害する シスプラチン誘導体はコラーゲンのin vitro線維化を阻害する シスプラチン誘導体はコラーゲンのin vitro線維化を阻害する 日本薬学会年会要旨集, 131st, 2, 195 日本薬学会年会要旨集, 131st, 2, 195 日本薬学会年会要旨集, 131st, 2, 195 2011/03/05 Japanese Disclose to all
TSUNEMATSU YUTA, HATTORI AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, KAKEYA HIDEAKI 恒松雄太, 服部明, 大石真也, 藤井信孝, 西村慎一, 掛谷秀昭 TSUNEMATSU YUTA, HATTORI AKIRA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, KAKEYA HIDEAKI 放線菌の生産する新規抗がんリード化合物tryptopeptin Aの化学構造決定 放線菌の生産する新規抗がんリード化合物tryptopeptin Aの化学構造決定 放線菌の生産する新規抗がんリード化合物tryptopeptin Aの化学構造決定 日本薬学会年会要旨集, 131st, 2, 104 日本薬学会年会要旨集, 131st, 2, 104 日本薬学会年会要旨集, 131st, 2, 104 2011/03/05 Japanese Disclose to all
MISU RYOSUKE, OISHI SHIN'YA, TOMITA KENJI, SETSUDA SHOHEI, MASUDA RYO, ONO HIROAKI, NAMBA YOSUKE, IEDA NAHOKO, INOUE NAOKO, OKURA SATOSHI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, HIRASAWA AKIRA, TSUJIMOTO GOZO, FUJII NOBUTAKA 三須良介, 大石真也, 富田健嗣, 説田章平, 増田亮, 大野浩章, 難波陽介, 家田菜穂子, 井上直子, 大蔵聡, 上野山賀久, 束村博子, 前多敬一郎, 平澤明, 辻本豪三, 藤井信孝 MISU RYOSUKE, OISHI SHIN'YA, TOMITA KENJI, SETSUDA SHOHEI, MASUDA RYO, ONO HIROAKI, NAMBA YOSUKE, IEDA NAHOKO, INOUE NAOKO, OKURA SATOSHI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, HIRASAWA AKIRA, TSUJIMOTO GOZO, FUJII NOBUTAKA GPR54リガンドによるNPFF受容体の活性化 GPR54リガンドによるNPFF受容体の活性化 GPR54リガンドによるNPFF受容体の活性化 日本薬学会年会要旨集, 131st, 2, 78 日本薬学会年会要旨集, 131st, 2, 78 日本薬学会年会要旨集, 131st, 2, 78 2011/03/05 Japanese Disclose to all
志村和也,大石真也,藤井信孝,松岡雅雄 志村和也,大石真也,藤井信孝,松岡雅雄 HIV-1 膜融合阻害剤に対する新規耐性メカニズムの解析 HIV-1 膜融合阻害剤に対する新規耐性メカニズムの解析 第25 回日本エイズ学会学術集会・総会、東京、2011 年11 月30 日-12 月2 日 第25 回日本エイズ学会学術集会・総会、東京、2011 年11 月30 日-12 月2 日 2011 Refereed Japanese Disclose to all
加藤文博,日向亮輔,川岸崇裕,大石真也,藤井信孝,三浦智行,五十嵐樹彦,小林剛 加藤文博,日向亮輔,川岸崇裕,大石真也,藤井信孝,三浦智行,五十嵐樹彦,小林剛 抗デングウイルス活性を有する薬剤の探索 抗デングウイルス活性を有する薬剤の探索 第18回トガ・フラビ・ペスチウイルス研究会、東京、2011年11月11日 第18回トガ・フラビ・ペスチウイルス研究会、東京、2011年11月11日 2011 Refereed Japanese Disclose to all
OISHI MASAYA, SHOJI MASAZUMI, OKAYASU YUICHI, TANIUCHI YUKIKO, YONEHARA HIROTO, OKUMA HARUO 大石真也, 小路正純, 岡安雄一, 谷内友希子, 米原博人, 大熊春夫 OISHI MASAYA, SHOJI MASAZUMI, OKAYASU YUICHI, TANIUCHI YUKIKO, YONEHARA HIROTO, OKUMA HARUO Scratch and Corrosion Resistance of an Aluminum Flange with an Electron Beam Modified Seal Edge シールエッジ部を電子ビーム改質したアルミフランジの耐スクラッチ及び耐食性 Scratch and Corrosion Resistance of an Aluminum Flange with an Electron Beam Modified Seal Edge J Vac Soc Jpn, 54, 3, 158-161 J Vac Soc Jpn, 54, 3, 158-161 J Vac Soc Jpn, 54, 3, 158-161 2011 Japanese Disclose to all
HIRANO KIMIO, INABA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 平野公夫, 稲葉祐介, 大石真也, 藤井信孝, 大野浩章 HIRANO KIMIO, INABA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒によるジインおよびトリイン誘導体の連続環化反応を用いた縮環型インドール誘導体の合成 金触媒によるジインおよびトリイン誘導体の連続環化反応を用いた縮環型インドール誘導体の合成 金触媒によるジインおよびトリイン誘導体の連続環化反応を用いた縮環型インドール誘導体の合成 有機合成シンポジウム講演要旨集, 98th, 80-81 有機合成シンポジウム講演要旨集, 98th, 80-81 有機合成シンポジウム講演要旨集, 98th, 80-81 2010/10/30 Japanese Disclose to all
TAKEUCHI TOMOKI, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 竹内智起, 大石真也, 渡部敏明, 大野浩章, 浅田直也, 北浦和夫, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOKI, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 構造活性相関シンポジウム講演要旨集, 38th, 26-27 構造活性相関シンポジウム講演要旨集, 38th, 26-27 構造活性相関シンポジウム講演要旨集, 38th, 26-27 2010/10/22 Japanese Disclose to all
TAKEUCHI TOMOKI, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 竹内智起, 大石真也, 渡部敏明, 大野浩章, 浅田直也, 北浦和夫, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOKI, OISHI SHIN'YA, WATANABE TOSHIAKI, ONO HIROAKI, ASADA NAOYA, KITAURA KAZUO, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 メディシナルケミストリーシンポジウム講演要旨集, 29th, 60-61 メディシナルケミストリーシンポジウム講演要旨集, 29th, 60-61 メディシナルケミストリーシンポジウム講演要旨集, 29th, 60-61 2010/10/18 Japanese Disclose to all
MASUDA RYO, OISHI SHIN'YA, TANAHARA NORIKO, ONO HIROAKI, HIRASAWA AKIRA, TSUJIMOTO GOZO, YANO YOSHIAKI, MATSUZAKI KATSUMI, FUJII NOBUTAKA 増田亮, 大石真也, 棚原憲子, 大野浩章, 平澤明, 辻本豪三, 矢野義明, 松崎勝巳, 藤井信孝 MASUDA RYO, OISHI SHIN'YA, TANAHARA NORIKO, ONO HIROAKI, HIRASAWA AKIRA, TSUJIMOTO GOZO, YANO YOSHIAKI, MATSUZAKI KATSUMI, FUJII NOBUTAKA 蛍光標識CXCR4受容体リガンドの創製と応用 蛍光標識CXCR4受容体リガンドの創製と応用 蛍光標識CXCR4受容体リガンドの創製と応用 メディシナルケミストリーシンポジウム講演要旨集, 29th, 256-257 メディシナルケミストリーシンポジウム講演要旨集, 29th, 256-257 メディシナルケミストリーシンポジウム講演要旨集, 29th, 256-257 2010/10/18 Japanese Disclose to all
SETSUDA SHOHEI, OISHI SHIN'YA, MISU RYOSUKE, TOMITA KENJI, MASUDA RYO, ONO HIROAKI, NANIWA YOSUKE, IEDA NAHOKO, INOUE NAOKO, OKURA SATOSHI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, HIRASAWA AKIRA, TSUJIMOTO GOZO, FUJII NOBUTAKA 説田章平, 大石真也, 三須良介, 富田健嗣, 増田亮, 大野浩章, 難波陽介, 家田菜穂子, 井上直子, 大蔵聡, 上野山賀久, 束村博子, 前多敬一郎, 平澤明, 辻本豪三, 藤井信孝 SETSUDA SHOHEI, OISHI SHIN'YA, MISU RYOSUKE, TOMITA KENJI, MASUDA RYO, ONO HIROAKI, NANIWA YOSUKE, IEDA NAHOKO, INOUE NAOKO, OKURA SATOSHI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, HIRASAWA AKIRA, TSUJIMOTO GOZO, FUJII NOBUTAKA GPR54受容体リガンドによるNPFF受容体の活性化 GPR54受容体リガンドによるNPFF受容体の活性化 GPR54受容体リガンドによるNPFF受容体の活性化 メディシナルケミストリーシンポジウム講演要旨集, 29th, 252-253 メディシナルケミストリーシンポジウム講演要旨集, 29th, 252-253 メディシナルケミストリーシンポジウム講演要旨集, 29th, 252-253 2010/10/18 Japanese Disclose to all
SUZUKI YAMATO, HOU ZENGYE, YASUE MISATO, HIRASAWA AKIRA, TSUJIMOTO GOZO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 鈴木大和, HOU Zengye, 安江美里, 平澤明, 辻本豪三, 大石真也, 大野浩章, 藤井信孝 SUZUKI YAMATO, HOU ZENGYE, YASUE MISATO, HIRASAWA AKIRA, TSUJIMOTO GOZO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 連続的多成分カップリング―環化反応によるピロロインドール及びジピロロピリジン誘導体の効率的合成法の開発 連続的多成分カップリング―環化反応によるピロロインドール及びジピロロピリジン誘導体の効率的合成法の開発 連続的多成分カップリング―環化反応によるピロロインドール及びジピロロピリジン誘導体の効率的合成法の開発 メディシナルケミストリーシンポジウム講演要旨集, 29th, 244-245 メディシナルケミストリーシンポジウム講演要旨集, 29th, 244-245 メディシナルケミストリーシンポジウム講演要旨集, 29th, 244-245 2010/10/18 Japanese Disclose to all
CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 遷移金属触媒を用いたSonogashiraカップリング―環化反応を鍵反応としたQuinocarcinの合成研究 遷移金属触媒を用いたSonogashiraカップリング―環化反応を鍵反応としたQuinocarcinの合成研究 遷移金属触媒を用いたSonogashiraカップリング―環化反応を鍵反応としたQuinocarcinの合成研究 反応と合成の進歩シンポジウム講演要旨集, 36th, 244-245 反応と合成の進歩シンポジウム講演要旨集, 36th, 244-245 反応と合成の進歩シンポジウム講演要旨集, 36th, 244-245 2010/10/12 Japanese Disclose to all
INUKI SHINSUKE, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 井貫晋輔, 吉光佑二, 大石真也, 藤井信孝, 大野浩章 INUKI SHINSUKE, YOSHIMITSU YUJI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒によるブロモアレンとプロパルギル化合物の連続環化反応を利用したJaspine Bの全合成とその応用 パラジウム触媒によるブロモアレンとプロパルギル化合物の連続環化反応を利用したJaspine Bの全合成とその応用 パラジウム触媒によるブロモアレンとプロパルギル化合物の連続環化反応を利用したJaspine Bの全合成とその応用 反応と合成の進歩シンポジウム講演要旨集, 36th, 322-323 反応と合成の進歩シンポジウム講演要旨集, 36th, 322-323 反応と合成の進歩シンポジウム講演要旨集, 36th, 322-323 2010/10/12 Japanese Disclose to all
HOU ZENGYE, SUZUKI YAMATO, YASUE MISATO, HIRASAWA AKIRA, TSUJIMOTO GOZO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA HOU Zengye, 鈴木大和, 安江美里, 平澤明, 辻本豪三, 大石真也, 大野浩章, 藤井信孝 HOU ZENGYE, SUZUKI YAMATO, YASUE MISATO, HIRASAWA AKIRA, TSUJIMOTO GOZO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA アザインドール骨格を有する新規CK2阻害剤テンプレートの開発研究 アザインドール骨格を有する新規CK2阻害剤テンプレートの開発研究 アザインドール骨格を有する新規CK2阻害剤テンプレートの開発研究 反応と合成の進歩シンポジウム講演要旨集, 36th, 250-251 反応と合成の進歩シンポジウム講演要旨集, 36th, 250-251 反応と合成の進歩シンポジウム講演要旨集, 36th, 250-251 2010/10/12 Japanese Disclose to all
TOKIMIZU YUSUKE, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 時水勇輔, 太田悠介, 大石真也, 藤井信孝, 大野浩章 TOKIMIZU YUSUKE, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 銅触媒を用いたオルト無置換ベンズアミジンのアルキニル化―環化によるキナゾリンの直接的合成 有機合成化学セミナー講演予稿集, 27th, 87 有機合成化学セミナー講演予稿集, 27th, 87 有機合成化学セミナー講演予稿集, 27th, 87 2010/09/02 Japanese Disclose to all
TSUNEMATSU YUTA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, HATTORI AKIRA, KAKEYA HIDEAKI 恒松雄太, 大石真也, 藤井信孝, 西村慎一, 服部明, 掛谷秀昭 TSUNEMATSU YUTA, OISHI SHIN'YA, FUJII NOBUTAKA, NISHIMURA SHIN'ICHI, HATTORI AKIRA, KAKEYA HIDEAKI 放線菌が生産する新規TGF‐βシグナル伝達阻害剤tryptopeptin Aの単離・構造解析と合成 放線菌が生産する新規TGF‐βシグナル伝達阻害剤tryptopeptin Aの単離・構造解析と合成 放線菌が生産する新規TGF‐βシグナル伝達阻害剤tryptopeptin Aの単離・構造解析と合成 天然有機化合物討論会講演要旨集, 52nd, 397-402 天然有機化合物討論会講演要旨集, 52nd, 397-402 天然有機化合物討論会講演要旨集, 52nd, 397-402 2010/09/01 Japanese Disclose to all
HONMA TAMAMI, WAKABAYASHI YOSHIHIRO, YAMAMURA TAKASHI, SAKAMOTO KOHEI, MURATA KEN, OKURA SATOSHI, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, MAEDA KEIICHIRO, OKAMURA HIROAKI 本間玲実, 若林嘉浩, 山村崇, 坂本光平, 村田健, 大蔵聡, 説田章平, 大石真也, 藤井信孝, 前多敬一郎, 岡村裕昭 HONMA TAMAMI, WAKABAYASHI YOSHIHIRO, YAMAMURA TAKASHI, SAKAMOTO KOHEI, MURATA KEN, OKURA SATOSHI, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, MAEDA KEIICHIRO, OKAMURA HIROAKI 合成キスペプチンアゴニストがシバヤギのLH分泌におよぼす効果の解析 合成キスペプチンアゴニストがシバヤギのLH分泌におよぼす効果の解析 合成キスペプチンアゴニストがシバヤギのLH分泌におよぼす効果の解析 J Reprod Dev, 56, Suppl Japanese Issue, J113 J Reprod Dev, 56, Suppl Japanese Issue, J113 J Reprod Dev, 56, Suppl Japanese Issue, J113 2010/08/20 Japanese Disclose to all
INOUE NAOKO, SASAKI YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, YAMAMOTO NAOYUKI, HONDO EIICHI, MAEDA KEIICHIRO, TSUKAMURA HIROKO 井上直子, 佐々木有希, 大石真也, 藤井信孝, 上野山賀久, 山本直之, 本道栄一, 前多敬一郎, 束村博子 INOUE NAOKO, SASAKI YUKI, OISHI SHIN'YA, FUJII NOBUTAKA, UENOYAMA YOSHIHISA, YAMAMOTO NAOYUKI, HONDO EIICHI, MAEDA KEIICHIRO, TSUKAMURA HIROKO スンクス脳におけるキスペプチンニューロンの局在ならびにキスペプチン排卵誘起効果の検討 スンクス脳におけるキスペプチンニューロンの局在ならびにキスペプチン排卵誘起効果の検討 スンクス脳におけるキスペプチンニューロンの局在ならびにキスペプチン排卵誘起効果の検討 J Reprod Dev, 56, Suppl Japanese Issue, J85 J Reprod Dev, 56, Suppl Japanese Issue, J85 J Reprod Dev, 56, Suppl Japanese Issue, J85 2010/08/20 Japanese Disclose to all
NAMBA YOSUKE, NAKATSUKASA KEISUKE, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, WAKABAYASHI YOSHIHIRO, OKAMURA HIROAKI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, OKURA SATOSHI 難波陽介, 中務桂佑, 説田章平, 大石真也, 藤井信孝, 若林嘉浩, 岡村裕昭, 上野山賀久, 束村博子, 前多敬一郎, 大蔵聡 NAMBA YOSUKE, NAKATSUKASA KEISUKE, TOKITA SHOHEI, OISHI SHIN'YA, FUJII NOBUTAKA, WAKABAYASHI YOSHIHIRO, OKAMURA HIROAKI, UENOYAMA YOSHIHISA, TSUKAMURA HIROKO, MAEDA KEIICHIRO, OKURA SATOSHI 黒毛和種成熟雌ウシにおけるウシ型キスペプチン投与が性腺刺激ホルモン分泌と卵胞発育におよぼす影響 黒毛和種成熟雌ウシにおけるウシ型キスペプチン投与が性腺刺激ホルモン分泌と卵胞発育におよぼす影響 黒毛和種成熟雌ウシにおけるウシ型キスペプチン投与が性腺刺激ホルモン分泌と卵胞発育におよぼす影響 J Reprod Dev, 56, Suppl Japanese Issue, J85 J Reprod Dev, 56, Suppl Japanese Issue, J85 J Reprod Dev, 56, Suppl Japanese Issue, J85 2010/08/20 Japanese Disclose to all
ZENDA MIYU, OISHI SHIN'YA, YAMAZAKI CHISATO, KOIDE TAKAKI 全田未悠, 大石真也, 山崎ちさと, 小出隆規 ZENDA MIYU, OISHI SHIN'YA, YAMAZAKI CHISATO, KOIDE TAKAKI コラーゲンの線維化を阻害する低分子量化合物の探索 コラーゲンの線維化を阻害する低分子量化合物の探索 コラーゲンの線維化を阻害する低分子量化合物の探索 日本結合組織学会学術大会抄録集, 42nd, 139 日本結合組織学会学術大会抄録集, 42nd, 139 日本結合組織学会学術大会抄録集, 42nd, 139 2010/08/02 Japanese Disclose to all
TAKEUCHI TOMOTATSU, WATANABE TOSHIAKI, OISHI SHIN'YA, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA 竹内智起, 渡部敏明, 大石真也, 大野浩章, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOTATSU, WATANABE TOSHIAKI, OISHI SHIN'YA, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIYOSHI, FUJII NOBUTAKA 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 日本薬学会年会要旨集, 130th, 2, 103 日本薬学会年会要旨集, 130th, 2, 103 日本薬学会年会要旨集, 130th, 2, 103 2010/03/05 Japanese Disclose to all
INABA YUSUKE, HIRANO KIMIO, WATANABE TOSHIAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 稲葉祐介, 平野公夫, 渡部敏明, 大石真也, 藤井信孝, 大野浩章 INABA YUSUKE, HIRANO KIMIO, WATANABE TOSHIAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 金触媒を用いたアニリン誘導体の分子内連続環化反応による芳香族縮環型カルバゾール誘導体の合成 金触媒を用いたアニリン誘導体の分子内連続環化反応による芳香族縮環型カルバゾール誘導体の合成 金触媒を用いたアニリン誘導体の分子内連続環化反応による芳香族縮環型カルバゾール誘導体の合成 日本薬学会年会要旨集, 130th, 2, 75 日本薬学会年会要旨集, 130th, 2, 75 日本薬学会年会要旨集, 130th, 2, 75 2010/03/05 Japanese Disclose to all
OKANO AKINORI, OISHI SHIN'YA, TANAKA TETSUAKI, FUJII NOBUTAKA, ONO HIROAKI 岡野晃典, 大石真也, 田中徹明, 藤井信孝, 大野浩章 OKANO AKINORI, OISHI SHIN'YA, TANAKA TETSUAKI, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒とイソシアネートを用いた2‐アルキニルアジリジンの環拡大―連続的環化反応による連結型複素環の構築 パラジウム触媒とイソシアネートを用いた2‐アルキニルアジリジンの環拡大―連続的環化反応による連結型複素環の構築 パラジウム触媒とイソシアネートを用いた2‐アルキニルアジリジンの環拡大―連続的環化反応による連結型複素環の構築 日本薬学会年会要旨集, 130th, 2, 75 日本薬学会年会要旨集, 130th, 2, 75 日本薬学会年会要旨集, 130th, 2, 75 2010/03/05 Japanese Disclose to all
BANDO HIROKI, TSUTSUMI HIROKO, KAJIWARA KAZUMI, OISHI SHIN'YA, MATSUOKA MASAO, FUJII NOBUTAKA, HATA YOJI 坂東弘樹, 堤浩子, 梶原一美, 大石真也, 松岡雅雄, 藤井信孝, 秦洋二 BANDO HIROKI, TSUTSUMI HIROKO, KAJIWARA KAZUMI, OISHI SHIN'YA, MATSUOKA MASAO, FUJII NOBUTAKA, HATA YOJI 麹菌A.oryzaeによる人工デザイン抗HIVペプチドの効率的分泌発現 麹菌A.oryzaeによる人工デザイン抗HIVペプチドの効率的分泌発現 麹菌A.oryzaeによる人工デザイン抗HIVペプチドの効率的分泌発現 日本農芸化学会大会講演要旨集, 2010, 88 日本農芸化学会大会講演要旨集, 2010, 88 日本農芸化学会大会講演要旨集, 2010, 88 2010/03/05 Japanese Disclose to all
OISHI SHIN'YA, KAJIWARA KAZUMI, TANAKA MICHINORI, ONO HIROAKI, FUJII NOBUTAKA 大石真也, 梶原一美, 田中理紀, 大野浩章, 藤井信孝 OISHI SHIN'YA, KAJIWARA KAZUMI, TANAKA MICHINORI, ONO HIROAKI, FUJII NOBUTAKA 薬剤耐性株に有効な抗HIV活性ペプチドの創製と発現生産プロセスの開発 薬剤耐性株に有効な抗HIV活性ペプチドの創製と発現生産プロセスの開発 薬剤耐性株に有効な抗HIV活性ペプチドの創製と発現生産プロセスの開発 日本薬学会年会要旨集, 130th, 1, 277 日本薬学会年会要旨集, 130th, 1, 277 日本薬学会年会要旨集, 130th, 1, 277 2010/03/05 Japanese Disclose to all
YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 吉光佑二, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 YOSHIMITSU YUJI, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Jaspine Bおよびその誘導体の立体選択的合成研究 Jaspine Bおよびその誘導体の立体選択的合成研究 Jaspine Bおよびその誘導体の立体選択的合成研究 日本薬学会年会要旨集, 130th, 2, 69 日本薬学会年会要旨集, 130th, 2, 69 日本薬学会年会要旨集, 130th, 2, 69 2010/03/05 Japanese Disclose to all
NISHIZAWA KOJI, NISHIYAMA HIROYUKI, OISHI SHIN'YA, WATABE JUN, SAITO RYOICHI, OGAWA OSAMU 西澤恒二, 西山博之, 大石真也, 渡部淳, 齊藤亮一, 小川修 NISHIZAWA KOJI, NISHIYAMA HIROYUKI, OISHI SHIN'YA, WATABE JUN, SAITO RYOICHI, OGAWA OSAMU ケモカイン受容体CXCR4の蛍光標識アンタゴニストによる膀胱癌のin vivoイメージング ケモカイン受容体CXCR4の蛍光標識アンタゴニストによる膀胱癌のin vivoイメージング ケモカイン受容体CXCR4の蛍光標識アンタゴニストによる膀胱癌のin vivoイメージング 日本泌尿器科学会雑誌, 101, 2, 526 日本泌尿器科学会雑誌, 101, 2, 526 日本泌尿器科学会雑誌, 101, 2, 526 2010/02/20 Japanese Disclose to all
OISHI SHIN'YA 大石真也 OISHI SHIN'YA 新しい抗菌薬の開発に向けて:キナーゼ阻害剤の骨格からの展開 新しい抗菌薬の開発に向けて:キナーゼ阻害剤の骨格からの展開 新しい抗菌薬の開発に向けて:キナーゼ阻害剤の骨格からの展開 ファルマシア, 46, 2, 177-178 ファルマシア, 46, 2, 177-178 ファルマシア, 46, 2, 177-178 2010/02/01 Japanese Disclose to all
TASHIRO AIKA, HATTORI AKIRA, PIAO JINHUA, YAMADA AI, OISHI SHIN'YA, FUJII NOBUTAKA, KAKEYA HIDEAKI 田代亜衣香, 服部明, PIAO Jinhua, 山田愛, 大石真也, 藤井信孝, 掛谷秀昭 TASHIRO AIKA, HATTORI AKIRA, PIAO JINHUA, YAMADA AI, OISHI SHIN'YA, FUJII NOBUTAKA, KAKEYA HIDEAKI 脱ユビキチン化酵素USP47の酵素学的性状解析 脱ユビキチン化酵素USP47の酵素学的性状解析 脱ユビキチン化酵素USP47の酵素学的性状解析 生化学, ROMBUNNO.4P-0562 生化学, ROMBUNNO.4P-0562 生化学, ROMBUNNO.4P-0562 2010 Japanese Disclose to all
OISHI SHIN'YA 大石真也 OISHI SHIN'YA ウイルスの変異に学ぶ抗HIV活性ペプチドのデザイン ウイルスの変異に学ぶ抗HIV活性ペプチドのデザイン ウイルスの変異に学ぶ抗HIV活性ペプチドのデザイン メディシナルケミストリーシンポジウム講演要旨集, 28th, 58-59 メディシナルケミストリーシンポジウム講演要旨集, 28th, 58-59 メディシナルケミストリーシンポジウム講演要旨集, 28th, 58-59 2009/11/10 Japanese Disclose to all
TAKEUCHI TOMOKI, WATANABE TOSHIAKI, OISHI SHIN'YA, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 竹内智起, 渡部敏明, 大石真也, 大野浩章, 澤田潤一, 浅井章良, 藤井信孝 TAKEUCHI TOMOKI, WATANABE TOSHIAKI, OISHI SHIN'YA, ONO HIROAKI, SAWADA JUN'ICHI, ASAI AKIRA, FUJII NOBUTAKA 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 縮環インドール構造を有する新規Eg5阻害剤の開発 メディシナルケミストリーシンポジウム講演要旨集, 28th, 86-87 メディシナルケミストリーシンポジウム講演要旨集, 28th, 86-87 メディシナルケミストリーシンポジウム講演要旨集, 28th, 86-87 2009/11/10 Japanese Disclose to all
HAYASHI RYOKO, OISHI SHIN'YA, TOMITA KENJI, NARUMI TETSUO, TANAHARA NORIKO, ONO HIROAKI, NAITO TAKESHI, KODAMA EIICHI, MATSUOKA MASAO, FUJII NOBUTAKA 林亮子, 大石真也, 富田健嗣, 鳴海哲夫, 棚原憲子, 大野浩章, 内藤武志, 児玉栄一, 松岡雅雄, 藤井信孝 HAYASHI RYOKO, OISHI SHIN'YA, TOMITA KENJI, NARUMI TETSUO, TANAHARA NORIKO, ONO HIROAKI, NAITO TAKESHI, KODAMA EIICHI, MATSUOKA MASAO, FUJII NOBUTAKA アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用 アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用 アルケン型ジペプチドイソスターの合成とケモカイン受容体CXCR4拮抗剤の構造活性相関研究への応用 メディシナルケミストリーシンポジウム講演要旨集, 28th, 116-117 メディシナルケミストリーシンポジウム講演要旨集, 28th, 116-117 メディシナルケミストリーシンポジウム講演要旨集, 28th, 116-117 2009/11/10 Japanese Disclose to all
MIZUHARA TSUKASA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 水原司, 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 MIZUHARA TSUKASA, INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒によるテトラヒドロピリミジンを配位性置換基とした酸化的分子間オルトC‐H官能基化反応 銅触媒によるテトラヒドロピリミジンを配位性置換基とした酸化的分子間オルトC‐H官能基化反応 銅触媒によるテトラヒドロピリミジンを配位性置換基とした酸化的分子間オルトC‐H官能基化反応 反応と合成の進歩シンポジウム講演要旨集, 35th, 234-235 反応と合成の進歩シンポジウム講演要旨集, 35th, 234-235 反応と合成の進歩シンポジウム講演要旨集, 35th, 234-235 2009/10/30 Japanese Disclose to all
KOBAYASHI KAZUYA, NARUMI TETSUO, INOGUCHI ERIKO, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 小林数也, 鳴海哲夫, 井ノ口恵利子, 富田健嗣, 大石真也, 大野浩章, 藤井信孝 KOBAYASHI KAZUYA, NARUMI TETSUO, INOGUCHI ERIKO, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 有機銅‐亜鉛複合試薬を用いたトリフルオロメチルアルケンジペプチドイソスターの新規合成法の開発 有機銅‐亜鉛複合試薬を用いたトリフルオロメチルアルケンジペプチドイソスターの新規合成法の開発 有機銅‐亜鉛複合試薬を用いたトリフルオロメチルアルケンジペプチドイソスターの新規合成法の開発 反応と合成の進歩シンポジウム講演要旨集, 35th, 142-143 反応と合成の進歩シンポジウム講演要旨集, 35th, 142-143 反応と合成の進歩シンポジウム講演要旨集, 35th, 142-143 2009/10/30 Japanese Disclose to all
OTA YUSUKE, KUBOTA YUJI, CHIBA HIROAKI, OISHI MASAYA, FUJII NOBUTAKA, ONO HIROAKI 太田悠介, 久保田悠史, 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 OTA YUSUKE, KUBOTA YUJI, CHIBA HIROAKI, OISHI MASAYA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒による多成分カップリング反応を用いたワンポット含窒素多環式複素環骨格構築法の開発 銅触媒による多成分カップリング反応を用いたワンポット含窒素多環式複素環骨格構築法の開発 銅触媒による多成分カップリング反応を用いたワンポット含窒素多環式複素環骨格構築法の開発 反応と合成の進歩シンポジウム講演要旨集, 35th, 154-155 反応と合成の進歩シンポジウム講演要旨集, 35th, 154-155 反応と合成の進歩シンポジウム講演要旨集, 35th, 154-155 2009/10/30 Japanese Disclose to all
SUZUKI YAMATO, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 鈴木大和, 太田悠介, 大石真也, 藤井信孝, 大野浩章 SUZUKI YAMATO, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 多成分カップリング・連続環化反応によるピロロインドール誘導体及びジピロロピリジン誘導体の合成研究 多成分カップリング・連続環化反応によるピロロインドール誘導体及びジピロロピリジン誘導体の合成研究 多成分カップリング・連続環化反応によるピロロインドール誘導体及びジピロロピリジン誘導体の合成研究 次世代を担う有機化学シンポジウム講演要旨集, 7th, 58-59 次世代を担う有機化学シンポジウム講演要旨集, 7th, 58-59 次世代を担う有機化学シンポジウム講演要旨集, 7th, 58-59 2009/05/22 Japanese Disclose to all
KAJIWARA KAZUMI, TOKIWA REI, WATANABE KENTARO, ONO HIROAKI, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, OISHI SHIN'YA, FUJII NOBUTAKA 梶原一美, 常盤礼, 渡辺健太郎, 大野浩章, 泉和樹, 児玉栄一, 松岡雅雄, 大石真也, 藤井信孝 KAJIWARA KAZUMI, TOKIWA REI, WATANABE KENTARO, ONO HIROAKI, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, OISHI SHIN'YA, FUJII NOBUTAKA エンドキャップ抗HIV活性ペプチドSC35EKの合成 エンドキャップ抗HIV活性ペプチドSC35EKの合成 エンドキャップ抗HIV活性ペプチドSC35EKの合成 日本薬学会年会要旨集, 129th, 2, 186 日本薬学会年会要旨集, 129th, 2, 186 日本薬学会年会要旨集, 129th, 2, 186 2009/03/05 Japanese Disclose to all
FUJITA ATSUHITO, YABUUCHI HIROAKI, OGAWA TEPPEI, ARAKI MICHIHIRO, OISHI SHIN'YA, FUJII NOBUTAKA, NAKAYAMA KAZUHISA, OKUNO YASUSHI 藤田淳人, 藪内弘昭, 小川哲平, 荒木通啓, 大石真也, 藤井信孝, 中山和久, 奥野恭史 FUJITA ATSUHITO, YABUUCHI HIROAKI, OGAWA TEPPEI, ARAKI MICHIHIRO, OISHI SHIN'YA, FUJII NOBUTAKA, NAKAYAMA KAZUHISA, OKUNO YASUSHI ケミカルゲデノミクス情報を用いた標的タンパク質の予測法の開発 ケミカルゲデノミクス情報を用いた標的タンパク質の予測法の開発 ケミカルゲデノミクス情報を用いた標的タンパク質の予測法の開発 日本薬学会年会要旨集, 129th, 4, 143 日本薬学会年会要旨集, 129th, 4, 143 日本薬学会年会要旨集, 129th, 4, 143 2009/03/05 Japanese Disclose to all
SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 鈴木大和, 大石真也, 藤井信孝, 大野浩章 SUZUKI YAMATO, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 新規三環性ヘテロ芳香環構築反応の開発とキナーゼ阻害剤テンプレートへの応用 新規三環性ヘテロ芳香環構築反応の開発とキナーゼ阻害剤テンプレートへの応用 新規三環性ヘテロ芳香環構築反応の開発とキナーゼ阻害剤テンプレートへの応用 日本薬学会年会要旨集, 129th, 2, 82 日本薬学会年会要旨集, 129th, 2, 82 日本薬学会年会要旨集, 129th, 2, 82 2009/03/05 Japanese Disclose to all
OISHI SHIN'YA 大石真也 OISHI SHIN'YA 高機能性ペプチドミメティクスの開発と環状生理活性ペプチドの分子認識機構解明への応用 高機能性ペプチドミメティクスの開発と環状生理活性ペプチドの分子認識機構解明への応用 高機能性ペプチドミメティクスの開発と環状生理活性ペプチドの分子認識機構解明への応用 日本薬学会年会要旨集, 129th, 1, 38 日本薬学会年会要旨集, 129th, 1, 38 日本薬学会年会要旨集, 129th, 1, 38 2009/03/05 Japanese Disclose to all
OTA YUSUKE, CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 太田悠介, 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 OTA YUSUKE, CHIBA KOSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒を用いた連続三成分結合形成反応による2‐(アミノメチル)インドール骨格およびインドール縮環型多環式骨格構築法の開発 銅触媒を用いた連続三成分結合形成反応による2‐(アミノメチル)インドール骨格およびインドール縮環型多環式骨格構築法の開発 銅触媒を用いた連続三成分結合形成反応による2‐(アミノメチル)インドール骨格およびインドール縮環型多環式骨格構築法の開発 日本薬学会年会要旨集, 129th, 1, 255 日本薬学会年会要旨集, 129th, 1, 255 日本薬学会年会要旨集, 129th, 1, 255 2009/03/05 Japanese Disclose to all
WATABE TOSHIAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 渡部敏明, 大石真也, 藤井信孝, 大野浩章 WATABE TOSHIAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒を用いたsp3C‐H活性化によるインドリンの合成 パラジウム触媒を用いたsp3C‐H活性化によるインドリンの合成 パラジウム触媒を用いたsp3C‐H活性化によるインドリンの合成 日本薬学会年会要旨集, 129th, 2, 234 日本薬学会年会要旨集, 129th, 2, 234 日本薬学会年会要旨集, 129th, 2, 234 2009/03/05 Japanese Disclose to all
HATTORI AKIRA, TSUNEMATSU YUTA, OTSUKA SAORI, TAKASU YASUAKI, NISHIMURA SHIN'ICHI, YAKURA TOORU, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMIZU SHIRO, OSADA HIROYUKI, KAKEYA HIDEAKI 服部明, 恒松雄太, 大塚紗織, 高須康明, 西村慎一, 矢倉徹, 大石真也, 藤井信孝, 清水史郎, 長田裕之, 掛谷秀昭 HATTORI AKIRA, TSUNEMATSU YUTA, OTSUKA SAORI, TAKASU YASUAKI, NISHIMURA SHIN'ICHI, YAKURA TOORU, OISHI SHIN'YA, FUJII NOBUTAKA, SHIMIZU SHIRO, OSADA HIROYUKI, KAKEYA HIDEAKI HIF‐1機能制御化合物の評価系構築と探索研究 HIF‐1機能制御化合物の評価系構築と探索研究 HIF‐1機能制御化合物の評価系構築と探索研究 日本薬学会年会要旨集, 129th, 2, 183 日本薬学会年会要旨集, 129th, 2, 183 日本薬学会年会要旨集, 129th, 2, 183 2009/03/05 Japanese Disclose to all
TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 富田健嗣, 大石真也, 大野浩章, 藤井信孝 TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 多様なジペプチドイソスターの分岐的合成とGPR54アゴニストへの応用 多様なジペプチドイソスターの分岐的合成とGPR54アゴニストへの応用 多様なジペプチドイソスターの分岐的合成とGPR54アゴニストへの応用 メディシナルケミストリーシンポジウム講演要旨集, 27th, 78-79 メディシナルケミストリーシンポジウム講演要旨集, 27th, 78-79 メディシナルケミストリーシンポジウム講演要旨集, 27th, 78-79 2008/11/10 Japanese Disclose to all
OKANO AKINORI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, MIZUTANI TSUYOSHI, TANAKA TETSUAKI 岡野晃典, 大石真也, 大野浩章, 藤井信孝, 水谷剛, 田中徹明 OKANO AKINORI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, MIZUTANI TSUYOSHI, TANAKA TETSUAKI パラジウム触媒を用いたブロモエンアレンの連続的閉環反応による多環式複素環の一挙構築 パラジウム触媒を用いたブロモエンアレンの連続的閉環反応による多環式複素環の一挙構築 パラジウム触媒を用いたブロモエンアレンの連続的閉環反応による多環式複素環の一挙構築 反応と合成の進歩シンポジウム講演要旨集, 34th, 270-271 反応と合成の進歩シンポジウム講演要旨集, 34th, 270-271 反応と合成の進歩シンポジウム講演要旨集, 34th, 270-271 2008/10/17 Japanese Disclose to all
INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 パラジウム触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 パラジウム触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 反応と合成の進歩シンポジウム講演要旨集, 34th, 92-93 反応と合成の進歩シンポジウム講演要旨集, 34th, 92-93 反応と合成の進歩シンポジウム講演要旨集, 34th, 92-93 2008/10/17 Japanese Disclose to all
OTA YUSUKE, CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 太田悠介, 千葉浩亮, 大石真也, 藤井信孝, 大野浩章 OTA YUSUKE, CHIBA HIROAKI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒‐マイクロ波照射を用いた連続三成分カップリング‐環化‐N‐アリール化反応によるインドール縮環型1,4‐ジアゼピン合成法の開発 銅触媒‐マイクロ波照射を用いた連続三成分カップリング‐環化‐N‐アリール化反応によるインドール縮環型1,4‐ジアゼピン合成法の開発 銅触媒‐マイクロ波照射を用いた連続三成分カップリング‐環化‐N‐アリール化反応によるインドール縮環型1,4‐ジアゼピン合成法の開発 反応と合成の進歩シンポジウム講演要旨集, 34th, 90-91 反応と合成の進歩シンポジウム講演要旨集, 34th, 90-91 反応と合成の進歩シンポジウム講演要旨集, 34th, 90-91 2008/10/17 Japanese Disclose to all
TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 富田健嗣, 大石真也, 大野浩章, 藤井信孝 TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA ジペプチドイソスターの分岐型合成による酵素耐性GPR54アゴニストの創出 ジペプチドイソスターの分岐型合成による酵素耐性GPR54アゴニストの創出 ジペプチドイソスターの分岐型合成による酵素耐性GPR54アゴニストの創出 反応と合成の進歩シンポジウム講演要旨集, 34th, 144-145 反応と合成の進歩シンポジウム講演要旨集, 34th, 144-145 反応と合成の進歩シンポジウム講演要旨集, 34th, 144-145 2008/10/17 Japanese Disclose to all
OISHI MASAYA, SHOJI MASAZUMI, TANIUCHI YUKIKO, TAMURA KAZUHIRO, MASAKI MITSUHIRO, TAKANO SHIRO, SOTOME KOICHI, OKUMA HARUO 大石真也, 小路正純, 谷内友希子, 田村和宏, 正木満博, 高野史郎, 早乙女光一, 大熊春夫 OISHI MASAYA, SHOJI MASAZUMI, TANIUCHI YUKIKO, TAMURA KAZUHIRO, MASAKI MITSUHIRO, TAKANO SHIRO, SOTOME KOICHI, OKUMA HARUO 放射線による圧力測定異常の実験的研究 放射線による圧力測定異常の実験的研究 放射線による圧力測定異常の実験的研究 J Vac Soc Jpn, 51, 6, 386-391 J Vac Soc Jpn, 51, 6, 386-391 J Vac Soc Jpn, 51, 6, 386-391 2008/06/20 Japanese Disclose to all
INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Pd触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 Pd触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 Pd触媒によるアレン連続環化反応を利用したErgot Alkaloid骨格の一挙構築法開発と応用 次世代を担う有機化学シンポジウム講演要旨集, 6th, 8-9 次世代を担う有機化学シンポジウム講演要旨集, 6th, 8-9 次世代を担う有機化学シンポジウム講演要旨集, 6th, 8-9 2008/05/30 Japanese Disclose to all
WATABE TSUYOSHI, OISHI SHIN'YA, NISHIKAWA HIROKI, WATANABE KENTARO, NAKANO HIROAKI, NAKATSU TOORU, ONO HIROAKI, KATO HIROAKI, KODAMA EIICHI, MATSUOKA MASAO, FUJII NOBUTAKA 渡部毅, 大石真也, 西川裕輝, 渡辺健太郎, 中野博明, 中津亨, 大野浩章, 加藤博章, 児玉栄一, 松岡雅雄, 藤井信孝 WATABE TSUYOSHI, OISHI SHIN'YA, NISHIKAWA HIROKI, WATANABE KENTARO, NAKANO HIROAKI, NAKATSU TOORU, ONO HIROAKI, KATO HIROAKI, KODAMA EIICHI, MATSUOKA MASAO, FUJII NOBUTAKA T‐20(Fuzeon)耐性HIV‐1変異株における6‐ヘリカルバンドル構造のX線構造解析 T‐20(Fuzeon)耐性HIV‐1変異株における6‐ヘリカルバンドル構造のX線構造解析 T‐20(Fuzeon)耐性HIV‐1変異株における6‐ヘリカルバンドル構造のX線構造解析 日本化学会講演予稿集, 88th, 2, 878 日本化学会講演予稿集, 88th, 2, 878 日本化学会講演予稿集, 88th, 2, 878 2008/03/12 Japanese Disclose to all
TANAKA TOMOHIRO, TABE YASUAKI, OHASHI NAMI, HASEYAMA MASAKI, TSUTSUMI HIROSHI, NOMURA WATARU, ITOYA KYOKO, ESAKA AI, OISHI SHIN'YA, FUJII NOBUTAKA, WANG Z, PEIPER S C, EVANS B, TAMAMURA HIROKAZU 田中智博, 田部泰章, 大橋南美, 長谷山正樹, 堤浩, 野村渉, 糸谷恭子, 江坂藍, 大石真也, 藤井信孝, WANG Z, PEIPER S C, EVANS B, 玉村啓和 TANAKA TOMOHIRO, TABE YASUAKI, OHASHI NAMI, HASEYAMA MASAKI, TSUTSUMI HIROSHI, NOMURA WATARU, ITOYA KYOKO, ESAKA AI, OISHI SHIN'YA, FUJII NOBUTAKA, WANG Z, PEIPER S C, EVANS B, TAMAMURA HIROKAZU 新規pharmacophoreを有するCXCR4アンタゴニストの構造活性相関研究 新規pharmacophoreを有するCXCR4アンタゴニストの構造活性相関研究 新規pharmacophoreを有するCXCR4アンタゴニストの構造活性相関研究 日本薬学会年会要旨集, 128th, 2, 84 日本薬学会年会要旨集, 128th, 2, 84 日本薬学会年会要旨集, 128th, 2, 84 2008/03/05 Japanese Disclose to all
YANO YOSHIAKI, YANO AKIKO, OISHI SHIN'YA, SUGIMOTO YUKIHIKO, TSUJIMOTO GOZO, FUJII NOBUTAKA, MATSUZAKI KATSUMI 矢野義明, 矢野亜希子, 大石真也, 杉本幸彦, 辻本豪三, 藤井信孝, 松崎勝巳 YANO YOSHIAKI, YANO AKIKO, OISHI SHIN'YA, SUGIMOTO YUKIHIKO, TSUJIMOTO GOZO, FUJII NOBUTAKA, MATSUZAKI KATSUMI 新規生細胞膜受容体蛍光ラベル法:コイルドコイルタグ‐プローブペア 新規生細胞膜受容体蛍光ラベル法:コイルドコイルタグ‐プローブペア 新規生細胞膜受容体蛍光ラベル法:コイルドコイルタグ‐プローブペア 日本薬学会年会要旨集, 128th, 4, 14 日本薬学会年会要旨集, 128th, 4, 14 日本薬学会年会要旨集, 128th, 4, 14 2008/03/05 Japanese Disclose to all
WATANABE KENTARO, OISHI SHIN'YA, ITO SAORI, TANAKA MASANORI, NISHIKAWA HIROKI, WATABE TAKESHI, IZUMI KAZUKI, SAKAGAMI YASUKO, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA 渡辺健太郎, 大石真也, 伊藤紗織, 田中理紀, 西川祐樹, 渡部毅, 泉和樹, 坂上泰子, 児玉栄一, 松岡雅雄, 大野浩章, 藤井信孝 WATANABE KENTARO, OISHI SHIN'YA, ITO SAORI, TANAKA MASANORI, NISHIKAWA HIROKI, WATABE TAKESHI, IZUMI KAZUKI, SAKAGAMI YASUKO, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA ヘリックス誘起モチーフを導入した抗HIVペプチドのデザインと合成 ヘリックス誘起モチーフを導入した抗HIVペプチドのデザインと合成 ヘリックス誘起モチーフを導入した抗HIVペプチドのデザインと合成 日本薬学会年会要旨集, 128th, 2, 49 日本薬学会年会要旨集, 128th, 2, 49 日本薬学会年会要旨集, 128th, 2, 49 2008/03/05 Japanese Disclose to all
INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 井貫晋輔, 大石真也, 藤井信孝, 大野浩章 INUKI SHINSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI パラジウム触媒を用いたアレンの連続環化反応によるErgot alkaloid骨格の一挙構築 パラジウム触媒を用いたアレンの連続環化反応によるErgot alkaloid骨格の一挙構築 パラジウム触媒を用いたアレンの連続環化反応によるErgot alkaloid骨格の一挙構築 日本薬学会年会要旨集, 128th, 2, 14 日本薬学会年会要旨集, 128th, 2, 14 日本薬学会年会要旨集, 128th, 2, 14 2008/03/05 Japanese Disclose to all
MASUDA AKIRA, OISHI SHIN'YA, UEDA SATOSHI, EVANS BARRY, PEIPER STEPHEN C., HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, FUJII NOBUTAKA 増田亮, 大石真也, 上田聡, EVANS Barry, PEIPER Stephen C., 平澤明, 辻本豪三, 大野浩章, 藤井信孝 MASUDA AKIRA, OISHI SHIN'YA, UEDA SATOSHI, EVANS BARRY, PEIPER STEPHEN C., HIRASAWA AKIRA, TSUJIMOTO GOZO, ONO HIROAKI, FUJII NOBUTAKA CXCR4受容体アンタゴニストの蛍光標識体の合成と応用 CXCR4受容体アンタゴニストの蛍光標識体の合成と応用 CXCR4受容体アンタゴニストの蛍光標識体の合成と応用 日本薬学会年会要旨集, 128th, 2, 52 日本薬学会年会要旨集, 128th, 2, 52 日本薬学会年会要旨集, 128th, 2, 52 2008/03/05 Japanese Disclose to all
KOBAYASHI KAZUYA, NARUMI TETSUO, INOKUCHI ERIKO, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 小林数也, 鳴海哲夫, 井ノ口恵利子, 富田健嗣, 大石真也, 大野浩章, 藤井信孝 KOBAYASHI KAZUYA, NARUMI TETSUO, INOKUCHI ERIKO, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 求核的CF<sub>3</sub>化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成 求核的CF<sub>3</sub>化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成 求核的CF<sub>3</sub>化反応による立体選択的トリフルオロメチルアルケン型ジペプチドイソスターの合成 日本薬学会年会要旨集, 128th, 2, 26 日本薬学会年会要旨集, 128th, 2, 26 日本薬学会年会要旨集, 128th, 2, 26 2008/03/05 Japanese Disclose to all
SUZUKI HIROKAZU, CLUZEAU JEROME, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, HARA TAKASHI, HIRASAWA AKIRA, TSUJIMOTO GOZO 鈴木大和, CLUZEAU Jerome, 大石真也, 大野浩章, 藤井信孝, 原貴史, 平澤明, 辻本豪三 SUZUKI HIROKAZU, CLUZEAU JEROME, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, HARA TAKASHI, HIRASAWA AKIRA, TSUJIMOTO GOZO ピラジンを母核とするCK2阻害剤の構造活性相関研究 ピラジンを母核とするCK2阻害剤の構造活性相関研究 ピラジンを母核とするCK2阻害剤の構造活性相関研究 日本薬学会年会要旨集, 128th, 2, 52 日本薬学会年会要旨集, 128th, 2, 52 日本薬学会年会要旨集, 128th, 2, 52 2008/03/05 Japanese Disclose to all
TOMITA KENJI, NARUMI TETSUO, NIIDA AYUMI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 富田健嗣, 鳴海哲夫, 新居田歩, 大石真也, 大野浩章, 藤井信孝 TOMITA KENJI, NARUMI TETSUO, NIIDA AYUMI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA シスアミド等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 シスアミド等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 シスアミド等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 日本薬学会年会要旨集, 128th, 2, 95 日本薬学会年会要旨集, 128th, 2, 95 日本薬学会年会要旨集, 128th, 2, 95 2008/03/05 Japanese Disclose to all
FUJII NOBUTAKA, OISHI SHIN'YA, NISHIKAWA HIROKI, WATANABE TSUYOSHI, ONO HIROAKI, UJIIE MAKOTO, TAGUCHI FUMIHIRO, KODAMA EIICHI, MATSUOKA MASAO 藤井信孝, 大石真也, 西川裕樹, 渡部毅, 大野浩章, 氏家誠, 田口文広, 児玉英一, 松岡雅雄 FUJII NOBUTAKA, OISHI SHIN'YA, NISHIKAWA HIROKI, WATANABE TSUYOSHI, ONO HIROAKI, UJIIE MAKOTO, TAGUCHI FUMIHIRO, KODAMA EIICHI, MATSUOKA MASAO Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究 Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究 Chemical Virologyを基盤とする新興・再興ウイルス侵入阻害剤の開発研究 ケミカルバイオロジーシンポジウム発表要旨集 第4回 化学-生物融合領域創成の軌跡 理研シンポジウム 平成20年, 41 ケミカルバイオロジーシンポジウム発表要旨集 第4回 化学-生物融合領域創成の軌跡 理研シンポジウム 平成20年, 41 ケミカルバイオロジーシンポジウム発表要旨集 第4回 化学-生物融合領域創成の軌跡 理研シンポジウム 平成20年, 41 2008 Japanese Disclose to all
NAITO TAKESHI, IZUMI KAZUKI, KODAMA EIICHI, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 内藤武志, 泉和樹, 児玉栄一, 大石真也, 藤井信孝, 松岡雅雄 NAITO TAKESHI, IZUMI KAZUKI, KODAMA EIICHI, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO C29水溶性誘導体SC29EKの抗HIV効果 C29水溶性誘導体SC29EKの抗HIV効果 C29水溶性誘導体SC29EKの抗HIV効果 日本エイズ学会誌, 9, 4, 404 日本エイズ学会誌, 9, 4, 404 日本エイズ学会誌, 9, 4, 404 2007/11/20 Japanese Disclose to all
SHIMANE KAZUKI, IZUMI KAZUKI, KODAMA EIICHI, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 嶋根和毅, 泉和樹, 児玉栄一, 大石真也, 藤井信孝, 松岡雅雄 SHIMANE KAZUKI, IZUMI KAZUKI, KODAMA EIICHI, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO T‐20誘導体の抗HIV効果 T‐20誘導体の抗HIV効果 T‐20誘導体の抗HIV効果 日本エイズ学会誌, 9, 4, 403 日本エイズ学会誌, 9, 4, 403 日本エイズ学会誌, 9, 4, 403 2007/11/20 Japanese Disclose to all
IZUMI KAZUKI, KODAMA EIICHI, SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO 泉和樹, 児玉栄一, 志村和也, 大石真也, 藤井信孝, 松岡雅雄 IZUMI KAZUKI, KODAMA EIICHI, SHIMURA KAZUYA, OISHI SHIN'YA, FUJII NOBUTAKA, MATSUOKA MASAO T‐20耐性変異を利用した融合阻薬剤の開発 T‐20耐性変異を利用した融合阻薬剤の開発 T‐20耐性変異を利用した融合阻薬剤の開発 日本エイズ学会誌, 9, 4, 404 日本エイズ学会誌, 9, 4, 404 日本エイズ学会誌, 9, 4, 404 2007/11/20 Japanese Disclose to all
KATO MANABU, UEDA SATOSHI, INUKI SHINSUKE, OISHI SHIN'YA, ONO HIROAKI, EVANS BARRY, WANG ZI-XUAN, PEIPER STEPHEN C., FUJII NOBUTAKA 加藤学, 上田聡, 井貫晋輔, 大石真也, 大野浩章, EVANS Barry, WANG Zi‐xuan, PEIPER Stephen C., 藤井信孝 KATO MANABU, UEDA SATOSHI, INUKI SHINSUKE, OISHI SHIN'YA, ONO HIROAKI, EVANS BARRY, WANG ZI-XUAN, PEIPER STEPHEN C., FUJII NOBUTAKA 新規非ペプチド性ケモカイン受容体CXCR4アンタゴニストの創製研究 新規非ペプチド性ケモカイン受容体CXCR4アンタゴニストの創製研究 新規非ペプチド性ケモカイン受容体CXCR4アンタゴニストの創製研究 メディシナルケミストリーシンポジウム講演要旨集, 26th, 238-239 メディシナルケミストリーシンポジウム講演要旨集, 26th, 238-239 メディシナルケミストリーシンポジウム講演要旨集, 26th, 238-239 2007/11/09 Japanese Disclose to all
TOMITA KENJI, NARUMI TETSUO, NIIDA AYUMI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 富田健嗣, 鳴海哲夫, 新居田歩, 大石真也, 大野浩章, 藤井信孝 TOMITA KENJI, NARUMI TETSUO, NIIDA AYUMI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA シス型アミド結合等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 シス型アミド結合等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 シス型アミド結合等価体としてのZ型アルケンおよびE型フルオロアルケンジペプチドイソスターの合成と応用 メディシナルケミストリーシンポジウム講演要旨集, 26th, 220-221 メディシナルケミストリーシンポジウム講演要旨集, 26th, 220-221 メディシナルケミストリーシンポジウム講演要旨集, 26th, 220-221 2007/11/09 Japanese Disclose to all
OGO NAOHISA, OISHI SHIN'YA, MATSUNO KENJI, SAWADA JUN'ICHI, FUJII NOBUTAKA, ASAI AKIRA 小郷尚久, 大石真也, 松野研司, 澤田潤一, 藤井信孝, 浅井章良 OGO NAOHISA, OISHI SHIN'YA, MATSUNO KENJI, SAWADA JUN'ICHI, FUJII NOBUTAKA, ASAI AKIRA Eg5阻害作用を有するシステイン誘導体の合成と構造活性相関 Eg5阻害作用を有するシステイン誘導体の合成と構造活性相関 Eg5阻害作用を有するシステイン誘導体の合成と構造活性相関 メディシナルケミストリーシンポジウム講演要旨集, 26th, 226-227 メディシナルケミストリーシンポジウム講演要旨集, 26th, 226-227 メディシナルケミストリーシンポジウム講演要旨集, 26th, 226-227 2007/11/09 Japanese Disclose to all
INOKUCHI ERIKO, NARUMI TETSUO, NIIDA AYUMU, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 井ノ口恵利子, 鳴海哲夫, 新居田歩, 富田健嗣, 大石真也, 大野浩章, 藤井信孝 INOKUCHI ERIKO, NARUMI TETSUO, NIIDA AYUMU, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA パラジウム触媒カルボニル化反応を用いたトリフルオロメチルアルケンジペプチドイソスターおよび類縁体の新規合成法の開発 パラジウム触媒カルボニル化反応を用いたトリフルオロメチルアルケンジペプチドイソスターおよび類縁体の新規合成法の開発 パラジウム触媒カルボニル化反応を用いたトリフルオロメチルアルケンジペプチドイソスターおよび類縁体の新規合成法の開発 反応と合成の進歩シンポジウム講演要旨集, 33rd, 76-77 反応と合成の進歩シンポジウム講演要旨集, 33rd, 76-77 反応と合成の進歩シンポジウム講演要旨集, 33rd, 76-77 2007/10/20 Japanese Disclose to all
ONO HIROAKI, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, IUCHI MUTSUMI, TANAKA TETSUAKI 大野浩章, 太田悠介, 大石真也, 藤井信孝, 井内睦美, 田中徹明 ONO HIROAKI, OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, IUCHI MUTSUMI, TANAKA TETSUAKI 連続結合形成反応による縮環型芳香族化合物の一挙合成法の開発 連続結合形成反応による縮環型芳香族化合物の一挙合成法の開発 連続結合形成反応による縮環型芳香族化合物の一挙合成法の開発 反応と合成の進歩シンポジウム講演要旨集, 33rd, 166-167 反応と合成の進歩シンポジウム講演要旨集, 33rd, 166-167 反応と合成の進歩シンポジウム講演要旨集, 33rd, 166-167 2007/10/20 Japanese Disclose to all
OISHI SHIN'YA, FUJII NOBUTAKA 大石真也, 藤井信孝 OISHI SHIN'YA, FUJII NOBUTAKA 生理活性物質のケミカルバイオロジー 3.創薬基盤としてのケミカルバイオロジー ペプチドをリードとした創薬 生理活性物質のケミカルバイオロジー 3.創薬基盤としてのケミカルバイオロジー ペプチドをリードとした創薬 生理活性物質のケミカルバイオロジー 3.創薬基盤としてのケミカルバイオロジー ペプチドをリードとした創薬 蛋白質 核酸 酵素, 52, 13, 1696-1701 蛋白質 核酸 酵素, 52, 13, 1696-1701 蛋白質 核酸 酵素, 52, 13, 1696-1701 2007/10/10 Japanese Disclose to all
KATAGIRI FUMIHIKO, NAGAI KAZUYUKI, KIDA ATSUSHI, TOMITA KENJI, OISHI SHIN'YA, TAKEYAMA MASAHARU, DOI RYUICHIRO, FUJII NOBUTAKA 片桐文彦, 長井和之, 木田睦士, 富田健嗣, 大石真也, 武山正治, 土井隆一郎, 藤井信孝 KATAGIRI FUMIHIKO, NAGAI KAZUYUKI, KIDA ATSUSHI, TOMITA KENJI, OISHI SHIN'YA, TAKEYAMA MASAHARU, DOI RYUICHIRO, FUJII NOBUTAKA 膵臓癌患者における血漿中metastin濃度 膵臓癌患者における血漿中metastin濃度 膵臓癌患者における血漿中metastin濃度 日本癌治療学会誌, 42, 2, 816 日本癌治療学会誌, 42, 2, 816 日本癌治療学会誌, 42, 2, 816 2007/09/20 Japanese Disclose to all
OISHI SHIN'YA, FUJII NOBUTAKA 大石真也, 藤井信孝 OISHI SHIN'YA, FUJII NOBUTAKA 創薬候補ペプチドの探索 2.ペプチドのデザイン・誘導体化 4)ケミカルバイオロジーを基盤とするペプチド創薬 創薬候補ペプチドの探索 2.ペプチドのデザイン・誘導体化 4)ケミカルバイオロジーを基盤とするペプチド創薬 創薬候補ペプチドの探索 2.ペプチドのデザイン・誘導体化 4)ケミカルバイオロジーを基盤とするペプチド創薬 遺伝子医学MOOK, 8, 87-91 遺伝子医学MOOK, 8, 87-91 遺伝子医学MOOK, 8, 87-91 2007/07/05 Japanese Disclose to all
WATABE TOSHIAKI, UEDA SATOSHI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 渡部敏明, 上田聡, 大石真也, 藤井信孝, 大野浩章 WATABE TOSHIAKI, UEDA SATOSHI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 次世代を担う有機化学シンポジウム講演要旨集, 5th, 44-45 次世代を担う有機化学シンポジウム講演要旨集, 5th, 44-45 次世代を担う有機化学シンポジウム講演要旨集, 5th, 44-45 2007/05/25 Japanese Disclose to all
OISHI SHIN'YA, FUJII NOBUTAKA 大石真也, 藤井信孝 OISHI SHIN'YA, FUJII NOBUTAKA ケミカルライゲーション―生合成でつくれないタンパク質をつくる ケミカルライゲーション―生合成でつくれないタンパク質をつくる ケミカルライゲーション―生合成でつくれないタンパク質をつくる 化学, 62, 4, 68-69 化学, 62, 4, 68-69 化学, 62, 4, 68-69 2007/04/01 Japanese Disclose to all
TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 富田健嗣, 大石真也, 大野浩章, 藤井信孝 TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA GPR54に対するフルオロベンゾイルペンタペプチドの構造親和性相関研究 GPR54に対するフルオロベンゾイルペンタペプチドの構造親和性相関研究 GPR54に対するフルオロベンゾイルペンタペプチドの構造親和性相関研究 日本薬学会年会要旨集, 127th, 4, 130 日本薬学会年会要旨集, 127th, 4, 130 日本薬学会年会要旨集, 127th, 4, 130 2007/03/05 Japanese Disclose to all
WATABE TOSHIAKI, UEDA SATOSHI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 渡部敏明, 上田聡, 大石真也, 藤井信孝, 大野浩章 WATABE TOSHIAKI, UEDA SATOSHI, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 Pd触媒を用いたタンデム型N‐アリール化―C‐H活性化によるカルバゾールの合成と反応機構の考察 日本薬学会年会要旨集, 127th, 4, 148 日本薬学会年会要旨集, 127th, 4, 148 日本薬学会年会要旨集, 127th, 4, 148 2007/03/05 Japanese Disclose to all
ITO SAORI, OISHI SHIN'YA, NISHIKAWA YUKI, TANAKA MASANORI, WATANABE KENTARO, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA 伊藤紗織, 大石真也, 西川裕輝, 田中理紀, 渡辺健太郎, 泉和樹, 児玉栄一, 松岡雅雄, 大野浩章, 藤井信孝 ITO SAORI, OISHI SHIN'YA, NISHIKAWA YUKI, TANAKA MASANORI, WATANABE KENTARO, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 日本薬学会年会要旨集, 127th, 4, 117 日本薬学会年会要旨集, 127th, 4, 117 日本薬学会年会要旨集, 127th, 4, 117 2007/03/05 Japanese Disclose to all
INOKUCHI ERIKO, NARUMI TETSUO, NIIDA AYUMI, KOBAYASHI KAZUYA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 井ノ口恵利子, 鳴海哲夫, 新居田歩, 小林数也, 大石真也, 大野浩章, 藤井信孝 INOKUCHI ERIKO, NARUMI TETSUO, NIIDA AYUMI, KOBAYASHI KAZUYA, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA (Z)‐トリフルオロメチルアルケン型ジペプチドイソスターの高立体選択的合成法 (Z)‐トリフルオロメチルアルケン型ジペプチドイソスターの高立体選択的合成法 (Z)‐トリフルオロメチルアルケン型ジペプチドイソスターの高立体選択的合成法 日本薬学会年会要旨集, 127th, 4, 21 日本薬学会年会要旨集, 127th, 4, 21 日本薬学会年会要旨集, 127th, 4, 21 2007/03/05 Japanese Disclose to all
泉和樹,西川裕輝,伊藤紗織,児玉栄一,志村和也,大石真也,藤井信孝,松岡雅雄 泉和樹,西川裕輝,伊藤紗織,児玉栄一,志村和也,大石真也,藤井信孝,松岡雅雄 T-20 耐性HIV-1 に対して有効な融合阻害薬の開発 T-20 耐性HIV-1 に対して有効な融合阻害薬の開発 第17 回抗ウイルス療法研究会、香川、 2007 年5 月25-26 日 第17 回抗ウイルス療法研究会、香川、 2007 年5 月25-26 日 2007 Refereed Japanese Disclose to all
泉和樹,児玉栄一,志村和也,大石真也,藤井信孝,松岡雅雄 泉和樹,児玉栄一,志村和也,大石真也,藤井信孝,松岡雅雄 T-20 耐性変異を利用した融 合阻害薬の開発 T-20 耐性変異を利用した融 合阻害薬の開発 第21回日本エイズ学会学術集会・総会、広島、2007 年11月28-30 日 第21回日本エイズ学会学術集会・総会、広島、2007 年11月28-30 日 2007 Refereed Japanese Disclose to all
内藤武志,泉和樹,西川裕輝,児玉栄一,大石真也,藤井信孝,松岡雅雄 内藤武志,泉和樹,西川裕輝,児玉栄一,大石真也,藤井信孝,松岡雅雄 C29 水溶性誘導体 SC29EK の抗HIV 効果 C29 水溶性誘導体 SC29EK の抗HIV 効果 第21 回日本エイズ学会学術集会・総会、広島、2007 年11月28-30 日 第21 回日本エイズ学会学術集会・総会、広島、2007 年11月28-30 日 2007 Refereed Japanese Disclose to all
OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 太田悠介, 大石真也, 藤井信孝, 大野浩章 OTA YUSUKE, OISHI SHIN'YA, FUJII NOBUTAKA, ONO HIROAKI 銅触媒を用いた三成分カップリングによる2‐(アミノメチル)インドール骨格構築法の開発 銅触媒を用いた三成分カップリングによる2‐(アミノメチル)インドール骨格構築法の開発 銅触媒を用いた三成分カップリングによる2‐(アミノメチル)インドール骨格構築法の開発 反応と合成の進歩シンポジウム講演要旨集, 32nd, 258-259 反応と合成の進歩シンポジウム講演要旨集, 32nd, 258-259 反応と合成の進歩シンポジウム講演要旨集, 32nd, 258-259 2006/11/20 Japanese Disclose to all
NARUMI TETSUO, TOMITA KENJI, INOKUCHI ERIKO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA 鳴海哲夫, 富田健嗣, 井ノ口恵利子, 大石真也, 大野浩章, 藤井信孝 NARUMI TETSUO, TOMITA KENJI, INOKUCHI ERIKO, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA パラジウム触媒による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成 パラジウム触媒による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成 パラジウム触媒による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成 反応と合成の進歩シンポジウム講演要旨集, 32nd, 252-253 反応と合成の進歩シンポジウム講演要旨集, 32nd, 252-253 反応と合成の進歩シンポジウム講演要旨集, 32nd, 252-253 2006/11/20 Japanese Disclose to all
OISHI SHIN'YA, NIIDA AYUMI, NARUMI TETSUO, TOMITA KENJI, INOKUCHI ERIKO, ONO HIROAKI, KITAURA KAZUO, FUJII NOBUTAKA, OTAKA AKIRA, INUI KEN'ICHI 大石真也, 新居田歩, 鳴海哲夫, 富田健嗣, 井ノ口恵利子, 大野浩章, 北浦和夫, 藤井信孝, 大高章, 乾賢一 OISHI SHIN'YA, NIIDA AYUMI, NARUMI TETSUO, TOMITA KENJI, INOKUCHI ERIKO, ONO HIROAKI, KITAURA KAZUO, FUJII NOBUTAKA, OTAKA AKIRA, INUI KEN'ICHI シスアミド等価型アルケンジペプチドイソスターの合成と応用 シスアミド等価型アルケンジペプチドイソスターの合成と応用 シスアミド等価型アルケンジペプチドイソスターの合成と応用 反応と合成の進歩シンポジウム講演要旨集, 32nd, 138-139 反応と合成の進歩シンポジウム講演要旨集, 32nd, 138-139 反応と合成の進歩シンポジウム講演要旨集, 32nd, 138-139 2006/11/20 Japanese Disclose to all
ITO SAORI, OISHI SHIN'YA, NISHIKAWA HIROKI, TANAKA MICHINORI, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA 伊藤紗織, 大石真也, 西川裕輝, 田中理紀, 泉和樹, 児玉栄一, 松岡雅雄, 大野浩章, 藤井信孝 ITO SAORI, OISHI SHIN'YA, NISHIKAWA HIROKI, TANAKA MICHINORI, IZUMI KAZUKI, KODAMA EIICHI, MATSUOKA MASAO, ONO HIROAKI, FUJII NOBUTAKA EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 EKコンセプトを利用した高活性HIV膜融合阻害剤の創製研究 メディシナルケミストリーシンポジウム講演要旨集, 25th, 62-63 メディシナルケミストリーシンポジウム講演要旨集, 25th, 62-63 メディシナルケミストリーシンポジウム講演要旨集, 25th, 62-63 2006/11/10 Japanese Disclose to all
OGAWA TEPPEI, TAMAMURA HIROKAZU, OJIDA AKIO, TSUTSUMI HIROSHI, NAKASHIMA HIDEKI, OISHI SHIN'YA, ONO HIROAKI, HAMACHI ITARU, FUJII NOBUTAKA 小川哲平, 玉村啓和, 王子田彰夫, 堤浩, 中島秀喜, 大石真也, 大野浩章, 浜地格, 藤井信孝 OGAWA TEPPEI, TAMAMURA HIROKAZU, OJIDA AKIO, TSUTSUMI HIROSHI, NAKASHIMA HIDEKI, OISHI SHIN'YA, ONO HIROAKI, HAMACHI ITARU, FUJII NOBUTAKA 二核亜鉛錯体構造を有する新規ケモカインレセプターCXCR4アンタゴニストの創製 二核亜鉛錯体構造を有する新規ケモカインレセプターCXCR4アンタゴニストの創製 二核亜鉛錯体構造を有する新規ケモカインレセプターCXCR4アンタゴニストの創製 メディシナルケミストリーシンポジウム講演要旨集, 25th, 70-71 メディシナルケミストリーシンポジウム講演要旨集, 25th, 70-71 メディシナルケミストリーシンポジウム講演要旨集, 25th, 70-71 2006/11/10 Japanese Disclose to all
TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, AKAMATSU MIKI 富田健嗣, 大石真也, 大野浩章, 藤井信孝, 赤松美紀 TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, FUJII NOBUTAKA, AKAMATSU MIKI Structure-activity relationship studies on GPR54 agonists GPR54アゴニストの構造活性相関研究 Structure-activity relationship studies on GPR54 agonists 構造活性相関シンポジウム講演要旨集, 34th, 23-26 構造活性相関シンポジウム講演要旨集, 34th, 23-26 構造活性相関シンポジウム講演要旨集, 34th, 23-26 2006/11/07 Japanese Disclose to all
FUJII NOBUTAKA, OISHI SHIN'YA, OTAKA AKIRA 藤井信孝, 大石真也, 大高章 FUJII NOBUTAKA, OISHI SHIN'YA, OTAKA AKIRA ケミカルバイオロジー タンパク質機能を調節する小分子の世界 プロテオミクスを基盤とするケミカルバイオロジー―情報から制御へ ケミカルバイオロジー タンパク質機能を調節する小分子の世界 プロテオミクスを基盤とするケミカルバイオロジー―情報から制御へ ケミカルバイオロジー タンパク質機能を調節する小分子の世界 プロテオミクスを基盤とするケミカルバイオロジー―情報から制御へ バイオニクス, 3, 10, 46-51 バイオニクス, 3, 10, 46-51 バイオニクス, 3, 10, 46-51 2006/10/01 Japanese Disclose to all
OISHI MASAYA, YORITA TETSUHIKO, TANIUCHI YUKIKO, SHOJI MASAZUMI, YONEHARA HIROTO, OKUMA HARUO 大石真也, 依田哲彦, 谷内友希子, 小路正純, 米原博人, 大熊春夫 OISHI MASAYA, YORITA TETSUHIKO, TANIUCHI YUKIKO, SHOJI MASAZUMI, YONEHARA HIROTO, OKUMA HARUO Misreading of Pressure Measurement by Radiation, and Its Measures 放射線等による圧力測定異常とその対策 Misreading of Pressure Measurement by Radiation, and Its Measures 真空, 49, 5, 302-305 真空, 49, 5, 302-305 真空, 49, 5, 302-305 2006/05/20 Japanese Disclose to all
NARUMI TETSUO, TOMITA TAKETSUGU, NIIDA AYUMI, OISHI SHIN'YA, OTAKA AKIRA, ONO HIROAKI, FUJII NOBUTAKA 鳴海哲夫, 富田健嗣, 新居田歩, 大石真也, 大高章, 大野浩章, 藤井信孝 NARUMI TETSUO, TOMITA TAKETSUGU, NIIDA AYUMI, OISHI SHIN'YA, OTAKA AKIRA, ONO HIROAKI, FUJII NOBUTAKA 有機金属による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成:多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成への展開 有機金属による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成:多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成への展開 有機金属による炭素‐フッ素結合切断を伴うフルオロアルケン骨格の合成:多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成への展開 次世代を担う有機化学シンポジウム講演要旨集, 4th, 62-63 次世代を担う有機化学シンポジウム講演要旨集, 4th, 62-63 次世代を担う有機化学シンポジウム講演要旨集, 4th, 62-63 2006/05/19 Japanese Disclose to all
TOMITA KENJI, NIIDA AYUMI, HARADA TOSHIYUKI, OISHI SHIN'YA, ONO HIROAKI, AKAMATSU MIKI, FUJII NOBUTAKA 富田健嗣, 新居田歩, 原田俊幸, 大石真也, 大野浩章, 赤松美紀, 藤井信孝 TOMITA KENJI, NIIDA AYUMI, HARADA TOSHIYUKI, OISHI SHIN'YA, ONO HIROAKI, AKAMATSU MIKI, FUJII NOBUTAKA ペンタペプチド性GPR54アゴニストのN末端領域における構造活性相関研究および定量的構造活性相関研究 ペンタペプチド性GPR54アゴニストのN末端領域における構造活性相関研究および定量的構造活性相関研究 ペンタペプチド性GPR54アゴニストのN末端領域における構造活性相関研究および定量的構造活性相関研究 日本薬学会年会要旨集, 126th, 4, 190 日本薬学会年会要旨集, 126th, 4, 190 日本薬学会年会要旨集, 126th, 4, 190 2006/03/06 Japanese Disclose to all
WATABE TOSHIAKI, ESAKA AI, OGAWA TEPPEI, UEDA SATOSHI, TAMAMURA HIROKAZU, OISHI SHIN'YA, TRENT JOHN O., WANG ZIXUAN, PEIPER STEPHAN C., FUJII NOBUTAKA 渡部敏明, 江坂藍, 小川哲平, 上田聡, 玉村啓和, 大石真也, TRENT John O., WANG Zixuan, PEIPER Stephan C., 藤井信孝 WATABE TOSHIAKI, ESAKA AI, OGAWA TEPPEI, UEDA SATOSHI, TAMAMURA HIROKAZU, OISHI SHIN'YA, TRENT JOHN O., WANG ZIXUAN, PEIPER STEPHAN C., FUJII NOBUTAKA 新規環状母核構造を有するCXCR4アンタゴニストの合成および構造活性相関研究 新規環状母核構造を有するCXCR4アンタゴニストの合成および構造活性相関研究 新規環状母核構造を有するCXCR4アンタゴニストの合成および構造活性相関研究 日本薬学会年会要旨集, 126th, 4, 183 日本薬学会年会要旨集, 126th, 4, 183 日本薬学会年会要旨集, 126th, 4, 183 2006/03/06 Japanese Disclose to all
NARUMI TETSUO, NIIDA AYUMI, TOMITA KENJI, OISHI SHIN'YA, OTAKA AKIRA, ONO HIROAKI, FUJII NOBUTAKA 鳴海哲夫, 新居田歩, 富田健嗣, 大石真也, 大高章, 大野浩章, 藤井信孝 NARUMI TETSUO, NIIDA AYUMI, TOMITA KENJI, OISHI SHIN'YA, OTAKA AKIRA, ONO HIROAKI, FUJII NOBUTAKA パラジウム触媒による炭素‐フッ素結合活性化を伴うフルオロアルケンイソスターの新規合成法の開発 パラジウム触媒による炭素‐フッ素結合活性化を伴うフルオロアルケンイソスターの新規合成法の開発 パラジウム触媒による炭素‐フッ素結合活性化を伴うフルオロアルケンイソスターの新規合成法の開発 日本薬学会年会要旨集, 126th, 4, 123 日本薬学会年会要旨集, 126th, 4, 123 日本薬学会年会要旨集, 126th, 4, 123 2006/03/06 Japanese Disclose to all
NARUMI TETSUO, MIYATANI TOSHIJIRO, NIIDA AYUMI, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA 鳴海哲夫, 宮谷敏次郎, 新居田歩, 富田健嗣, 大石真也, 大野浩章, 大高章, 藤井信孝 NARUMI TETSUO, MIYATANI TOSHIJIRO, NIIDA AYUMI, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA フルオロアルケンイソスターの高立体選択的合成法の開発と生理活性ペプチドへの応用 フルオロアルケンイソスターの高立体選択的合成法の開発と生理活性ペプチドへの応用 フルオロアルケンイソスターの高立体選択的合成法の開発と生理活性ペプチドへの応用 日本薬学会年会要旨集, 126th, 4, 122 日本薬学会年会要旨集, 126th, 4, 122 日本薬学会年会要旨集, 126th, 4, 122 2006/03/06 Japanese Disclose to all
OISHI SHIN'YA, SHOJI MASAZUMI, TANIUCHI YUKIKO, TAKANO SHIRO, SAOTOME KOICHI, OKUMA HARUO 大石真也, 小路正純, 谷内友希子, 高野史郎, 早乙女光一, 大熊春夫 OISHI SHIN'YA, SHOJI MASAZUMI, TANIUCHI YUKIKO, TAKANO SHIRO, SAOTOME KOICHI, OKUMA HARUO 放射線による圧力測定異常の実験的研究 放射線による圧力測定異常の実験的研究 放射線による圧力測定異常の実験的研究 真空に関する連合講演会講演予稿集, 47th, 174 真空に関する連合講演会講演予稿集, 47th, 174 真空に関する連合講演会講演予稿集, 47th, 174 2006 Japanese Disclose to all
TOMITA KENJI, NIIDA AYUMU, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA 富田健嗣, 新居田歩, 大石真也, 大野浩章, 大高章, 藤井信孝 TOMITA KENJI, NIIDA AYUMU, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA 低分子GPR54作動剤の構造活性相関研究 低分子GPR54作動剤の構造活性相関研究 低分子GPR54作動剤の構造活性相関研究 メディシナルケミストリーシンポジウム講演要旨集, 24th, 94-95 メディシナルケミストリーシンポジウム講演要旨集, 24th, 94-95 メディシナルケミストリーシンポジウム講演要旨集, 24th, 94-95 2005/11/10 Japanese Disclose to all
NARUMI TETSUO, NIIDA AYUMU, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA 鳴海哲夫, 新居田歩, 富田健嗣, 大石真也, 大野浩章, 大高章, 藤井信孝 NARUMI TETSUO, NIIDA AYUMU, TOMITA KENJI, OISHI SHIN'YA, ONO HIROAKI, OTAKA AKIRA, FUJII NOBUTAKA 多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成法の開発 多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成法の開発 多価官能基を有するフルオロアルケン型ジペプチドイソスターの高立体選択的合成法の開発 メディシナルケミストリーシンポジウム講演要旨集, 24th, 130-131 メディシナルケミストリーシンポジウム講演要旨集, 24th, 130-131 メディシナルケミストリーシンポジウム講演要旨集, 24th, 130-131 2005/11/10 Japanese Disclose to all
OISHI SHIN'YA, SHI ZHEN-DAN, KARKI RAJESHRI G., WORTHY KAREN M., BINDU LAKSMAN, CHERTOV OLEG, ESPOSITO DOMINIC, FRANK PETER, GILLETTE WILLIAM K. 大石真也, SHI Zhen‐Dan, KARKI Rajeshri G., WORTHY Karen M., BINDU Laksman, CHERTOV Oleg, ESPOSITO Dominic, FRANK Peter, GILLETTE William K. OISHI SHIN'YA, SHI ZHEN-DAN, KARKI RAJESHRI G., WORTHY KAREN M., BINDU LAKSMAN, CHERTOV OLEG, ESPOSITO DOMINIC, FRANK PETER, GILLETTE WILLIAM K. 新規リン酸化チロシンミメティックの合成と環状Grb2 SH2ドメイン阻害剤への応用研究 新規リン酸化チロシンミメティックの合成と環状Grb2 SH2ドメイン阻害剤への応用研究 新規リン酸化チロシンミメティックの合成と環状Grb2 SH2ドメイン阻害剤への応用研究 日本薬学会年会要旨集, 125th, 4, 197 日本薬学会年会要旨集, 125th, 4, 197 日本薬学会年会要旨集, 125th, 4, 197 2005/03/05 Japanese Disclose to all
NIIDA AYUMI, OISHI SHIN'YA, FUJII NOBUTAKA, DOI RYUICHIRO, MORI TOMOHIKO, IMAMURA MASAYUKI, PEIPER S C, BROACH J A 新居田歩, 大石真也, 藤井信孝, 土井隆一郎, 森友彦, 今村正之, PEIPER S C, BROACH J A NIIDA AYUMI, OISHI SHIN'YA, FUJII NOBUTAKA, DOI RYUICHIRO, MORI TOMOHIKO, IMAMURA MASAYUKI, PEIPER S C, BROACH J A 癌転移抑制遺伝子産物(metastin)をリードとする創薬研究 癌転移抑制遺伝子産物(metastin)をリードとする創薬研究 癌転移抑制遺伝子産物(metastin)をリードとする創薬研究 日本薬学会年会要旨集, 124th, 2, 180 日本薬学会年会要旨集, 124th, 2, 180 日本薬学会年会要旨集, 124th, 2, 180 2004/03/05 Japanese Disclose to all
ARAKI TAKENOBU, UEDA SATOSHI, HIRAMATSU KEN'ICHI, OISHI SHIN'YA, OTAKA AKIRA, FUJII NOBUTAKA, KUSANO SHUICHI, TERAKUBO SHIGEMI, WANG Z 荒木威亘, 上田聡, 平松健一, 大石真也, 大高章, 藤井信孝, 草野秀一, 寺久保繁美, WANG Z ARAKI TAKENOBU, UEDA SATOSHI, HIRAMATSU KEN'ICHI, OISHI SHIN'YA, OTAKA AKIRA, FUJII NOBUTAKA, KUSANO SHUICHI, TERAKUBO SHIGEMI, WANG Z 新規Convergent Libraryを活用した高活性CXCR4アンタゴニストT140の低分子化 新規Convergent Libraryを活用した高活性CXCR4アンタゴニストT140の低分子化 新規Convergent Libraryを活用した高活性CXCR4アンタゴニストT140の低分子化 反応と合成の進歩シンポジウム講演要旨集, 29th, 192-193 反応と合成の進歩シンポジウム講演要旨集, 29th, 192-193 反応と合成の進歩シンポジウム講演要旨集, 29th, 192-193 2003/09/24 Japanese Disclose to all
ARAIDA AYUMU, MIZUMOTO MAKIKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA 新居田歩, 水本真紀子, 大石真也, 玉村啓和, 大高章, 藤井信孝 ARAIDA AYUMU, MIZUMOTO MAKIKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA Ru‐触媒閉環メタセシス反応と有機銅試薬による還元的アルキル化を共役させたジケトピペラジンメティックの合成 Ru‐触媒閉環メタセシス反応と有機銅試薬による還元的アルキル化を共役させたジケトピペラジンメティックの合成 Ru‐触媒閉環メタセシス反応と有機銅試薬による還元的アルキル化を共役させたジケトピペラジンメティックの合成 日本薬学会年会要旨集, 123rd, 2, 26 日本薬学会年会要旨集, 123rd, 2, 26 日本薬学会年会要旨集, 123rd, 2, 26 2003/03/05 Japanese Disclose to all
OISHI SHIN'YA, NIIDA AYUMU, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, AJITO KEIICHI, HAMANAKA NOBUYUKI 大石真也, 新居田歩, 鎌野高恵, 玉村啓和, 大高章, 藤井信孝, 味戸慶一, 浜中信行 OISHI SHIN'YA, NIIDA AYUMU, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, AJITO KEIICHI, HAMANAKA NOBUYUKI 立体配座固定ペプチドリード創薬テンプレートの研究 (Part2) 多置換アルケン型ジペプチドイソスターによる環状RGDペプチドの立体配座及び活性制御 立体配座固定ペプチドリード創薬テンプレートの研究 (Part2) 多置換アルケン型ジペプチドイソスターによる環状RGDペプチドの立体配座及び活性制御 立体配座固定ペプチドリード創薬テンプレートの研究 (Part2) 多置換アルケン型ジペプチドイソスターによる環状RGDペプチドの立体配座及び活性制御 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 22nd-11th, 68-70 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 22nd-11th, 68-70 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 22nd-11th, 68-70 2002/11/05 Japanese Disclose to all
OISHI SHIN'YA, ARAIDA AYUMU, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA 大石真也, 新居田歩, 鎌野高恵, 玉村啓和, 大高章, 藤井信孝 OISHI SHIN'YA, ARAIDA AYUMU, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA 三置換・四置換アルケン型ジペプチドイソスターの合成と環状RGDペプチドへの応用 三置換・四置換アルケン型ジペプチドイソスターの合成と環状RGDペプチドへの応用 三置換・四置換アルケン型ジペプチドイソスターの合成と環状RGDペプチドへの応用 情報化学討論会・構造活性相関シンポジウム講演要旨集, 25th-30th, 238-239 情報化学討論会・構造活性相関シンポジウム講演要旨集, 25th-30th, 238-239 情報化学討論会・構造活性相関シンポジウム講演要旨集, 25th-30th, 238-239 2002/10/25 Japanese Disclose to all
TAMAMURA HIROKAZU, NEMOTO KOJI, OISHI SHIN'YA, YAMASHITA MASAKI, OTAKA AKIRA, FUJII NOBUTAKA 玉村啓和, 根本浩二, 大石真也, 山下正樹, 大高章, 藤井信孝 TAMAMURA HIROKAZU, NEMOTO KOJI, OISHI SHIN'YA, YAMASHITA MASAKI, OTAKA AKIRA, FUJII NOBUTAKA 酸触媒によるアジリジンの開環反応と高官能性(E)‐アルケンジペプチドイソスターの完全立体制御型合成 (Xaa,L‐Glu),(Xaa,D‐Glu)タイプイソスターの合成 酸触媒によるアジリジンの開環反応と高官能性(E)‐アルケンジペプチドイソスターの完全立体制御型合成 (Xaa,L‐Glu),(Xaa,D‐Glu)タイプイソスターの合成 酸触媒によるアジリジンの開環反応と高官能性(E)‐アルケンジペプチドイソスターの完全立体制御型合成 (Xaa,L‐Glu),(Xaa,D‐Glu)タイプイソスターの合成 反応と合成の進歩シンポジウム講演要旨集, 28th, 202-203 反応と合成の進歩シンポジウム講演要旨集, 28th, 202-203 反応と合成の進歩シンポジウム講演要旨集, 28th, 202-203 2002/10/15 Japanese Disclose to all
OTAKA AKIRA, SASAKI YOSHIKAZU, KATAGIRI FUMIHIKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, FUJII NOBUTAKA 大高章, 佐々木義一, 片桐文彦, 大石真也, 玉村啓和, 藤井信孝 OTAKA AKIRA, SASAKI YOSHIKAZU, KATAGIRI FUMIHIKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, FUJII NOBUTAKA 有機銅試薬を利用したアルケン型Xaa‐Proジペプチドイソスターの立体選択的合成 有機銅試薬を利用したアルケン型Xaa‐Proジペプチドイソスターの立体選択的合成 有機銅試薬を利用したアルケン型Xaa‐Proジペプチドイソスターの立体選択的合成 反応と合成の進歩シンポジウム講演要旨集, 28th, 158-159 反応と合成の進歩シンポジウム講演要旨集, 28th, 158-159 反応と合成の進歩シンポジウム講演要旨集, 28th, 158-159 2002/10/15 Japanese Disclose to all
ARAIDA AYUMU, OISHI SHIN'YA, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA 新居田歩, 大石真也, 鎌野高恵, 玉村啓和, 大高章, 藤井信孝 ARAIDA AYUMU, OISHI SHIN'YA, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA キラルオキサゾリジノン誘導体を基質とする有機銅試薬による立体選択的多置換型アルケンの構築とジペプチドイソスターへの応用 キラルオキサゾリジノン誘導体を基質とする有機銅試薬による立体選択的多置換型アルケンの構築とジペプチドイソスターへの応用 キラルオキサゾリジノン誘導体を基質とする有機銅試薬による立体選択的多置換型アルケンの構築とジペプチドイソスターへの応用 日本薬学会年会要旨集, 122nd, 2, 80 日本薬学会年会要旨集, 122nd, 2, 80 日本薬学会年会要旨集, 122nd, 2, 80 2002/03/05 Japanese Disclose to all
NEMOTO KOJI, TAMAMURA HIROKAZU, OISHI SHIN'YA, OTAKA AKIRA, FUJII NOBUTAKA 根本浩二, 玉村啓和, 大石真也, 大高章, 藤井信孝 NEMOTO KOJI, TAMAMURA HIROKAZU, OISHI SHIN'YA, OTAKA AKIRA, FUJII NOBUTAKA β‐アジリジノ‐α,β‐不飽和エステルの酸触媒開環反応とその応用 β‐アジリジノ‐α,β‐不飽和エステルの酸触媒開環反応とその応用 β‐アジリジノ‐α,β‐不飽和エステルの酸触媒開環反応とその応用 日本薬学会年会要旨集, 122nd, 2, 80 日本薬学会年会要旨集, 122nd, 2, 80 日本薬学会年会要旨集, 122nd, 2, 80 2002/03/05 Japanese Disclose to all
OGAWA MIKAKO, HATANO KENTARO, KAWAKADO YASUHIRO, ITO KENGO, OISHI SHIN'YA, FUJII NOBUTAKA, KAWAGUCHI MICHIYA, YAMAMOTO MIKIO, IIDA HIDEHIRO 小川美香子, はた野健太郎, 川角保弘, 伊藤健吾, 大石真也, 藤井信孝, 川口道也, 山本幹夫, 飯田秀博 OGAWA MIKAKO, HATANO KENTARO, KAWAKADO YASUHIRO, ITO KENGO, OISHI SHIN'YA, FUJII NOBUTAKA, KAWAGUCHI MICHIYA, YAMAMOTO MIKIO, IIDA HIDEHIRO ペプチドの[<sup>18</sup>F]AcOFによる直接フッ素‐18標識法の開発 ペプチドの[<sup>18</sup>F]AcOFによる直接フッ素‐18標識法の開発 ペプチドの[<sup>18</sup>F]AcOFによる直接フッ素‐18標識法の開発 日本薬学会年会要旨集, 122nd, 3, 66 日本薬学会年会要旨集, 122nd, 3, 66 日本薬学会年会要旨集, 122nd, 3, 66 2002/03/05 Japanese Disclose to all
OISHI SHIN'YA, KAMANO TAKAE, NIIDA AYUMU, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, AJITO KEIICHI, HAMANAKA NOBUYUKI 大石真也, 鎌野高恵, 新居田歩, 玉村啓和, 大高章, 藤井信孝, 味戸慶一, 浜中信行 OISHI SHIN'YA, KAMANO TAKAE, NIIDA AYUMU, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, AJITO KEIICHI, HAMANAKA NOBUYUKI アミノ酸をキラルプールとする三置換・四置換アルケン型ジペプチドイソスターの立体選択的合成と環状RGDペプチドへの応用 アミノ酸をキラルプールとする三置換・四置換アルケン型ジペプチドイソスターの立体選択的合成と環状RGDペプチドへの応用 アミノ酸をキラルプールとする三置換・四置換アルケン型ジペプチドイソスターの立体選択的合成と環状RGDペプチドへの応用 反応と合成の進歩シンポジウム講演要旨集, 27th, 8-9 反応と合成の進歩シンポジウム講演要旨集, 27th, 8-9 反応と合成の進歩シンポジウム講演要旨集, 27th, 8-9 2001/10/20 Japanese Disclose to all
OTAKA AKIRA, YUKIMASA AKIRA, WATANABE JUNKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, FUJII NOBUTAKA 大高章, 行正顕, 渡辺順子, 大石真也, 玉村啓和, 藤井信孝 OTAKA AKIRA, YUKIMASA AKIRA, WATANABE JUNKO, OISHI SHIN'YA, TAMAMURA HIROKAZU, FUJII NOBUTAKA Samarium diiodide(SmI<sub>2</sub>)を利用したアルケン型ジペプチドイソスターの合成 Samarium diiodide(SmI<sub>2</sub>)を利用したアルケン型ジペプチドイソスターの合成 Samarium diiodide(SmI<sub>2</sub>)を利用したアルケン型ジペプチドイソスターの合成 反応と合成の進歩シンポジウム講演要旨集, 27th, 198-199 反応と合成の進歩シンポジウム講演要旨集, 27th, 198-199 反応と合成の進歩シンポジウム講演要旨集, 27th, 198-199 2001/10/20 Japanese Disclose to all
OGAWA MIKAKO, HATANO KENTARO, ITO KENGO, KAWAKADO YASUHIRO, KAWAGUCHI MICHIYA, DOI RYUICHIRO, OISHI SHIN'YA, FUJII NOBUTAKA 小川美香子, はた野健太郎, 伊藤健吾, 川角保広, 川口道也, 土井隆一郎, 大石真也, 藤井信孝 OGAWA MIKAKO, HATANO KENTARO, ITO KENGO, KAWAKADO YASUHIRO, KAWAGUCHI MICHIYA, DOI RYUICHIRO, OISHI SHIN'YA, FUJII NOBUTAKA α<sub>v</sub>β<sub>3</sub>インテグリンをターゲットとした<sup>18</sup>F標識新規腫ようイメージング剤の開発 α<sub>v</sub>β<sub>3</sub>インテグリンをターゲットとした<sup>18</sup>F標識新規腫ようイメージング剤の開発 α<sub>v</sub>β<sub>3</sub>インテグリンをターゲットとした<sup>18</sup>F標識新規腫ようイメージング剤の開発 核医学, 38, 5, 579 核医学, 38, 5, 579 核医学, 38, 5, 579 2001/09/20 Japanese Disclose to all
TAMAMURA HIROKAZU, OMAGARI AKANE, SUGA YUKIKO, OISHI MASAYA, NAKAJIMA HIDEKI, HAMANAKA NOBUYUKI, OTAKA AKIRA, FUJII NOBUTAKA 玉村啓和, 大曲亜香音, 菅由紀子, 大石真也, 中島秀喜, 浜中信行, 大高章, 藤井信孝 TAMAMURA HIROKAZU, OMAGARI AKANE, SUGA YUKIKO, OISHI MASAYA, NAKAJIMA HIDEKI, HAMANAKA NOBUYUKI, OTAKA AKIRA, FUJII NOBUTAKA HIV第二受容体きっ抗剤T140の立体構造解析とそのpharmacophoreの同定研究 HIV第二受容体きっ抗剤T140の立体構造解析とそのpharmacophoreの同定研究 HIV第二受容体きっ抗剤T140の立体構造解析とそのpharmacophoreの同定研究 日本薬学会年会要旨集, 121st, 3, 11 日本薬学会年会要旨集, 121st, 3, 11 日本薬学会年会要旨集, 121st, 3, 11 2001/03/05 Japanese Disclose to all
FUJII NOBUTAKA, TAMAMURA HIROKAZU, OMAGARI AKANE, OISHI SHIN'YA, OTAKA AKIRA, NAKASHIMA HIDEKI, KAMBARA KENJI 藤井信孝, 玉村啓和, 大曲亜香音, 大石真也, 大高章, 中島秀喜, 神原賢治 FUJII NOBUTAKA, TAMAMURA HIROKAZU, OMAGARI AKANE, OISHI SHIN'YA, OTAKA AKIRA, NAKASHIMA HIDEKI, KAMBARA KENJI 特異的CXCR4‐chemokineきっ抗剤,T140の非ペプチド化研究 特異的CXCR4‐chemokineきっ抗剤,T140の非ペプチド化研究 特異的CXCR4‐chemokineきっ抗剤,T140の非ペプチド化研究 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 20th-9th, 57-58 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 20th-9th, 57-58 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 20th-9th, 57-58 2000/11/08 Japanese Disclose to all
OISHI SHIN'YA, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA 大石真也, 鎌野高恵, 玉村啓和, 大高章, 藤井信孝 OISHI SHIN'YA, KAMANO TAKAE, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA N‐活性化ジエニルアジリジンの位置および立体選択的アルキル化反応の開発 N‐活性化ジエニルアジリジンの位置および立体選択的アルキル化反応の開発 N‐活性化ジエニルアジリジンの位置および立体選択的アルキル化反応の開発 反応と合成の進歩シンポジウム講演要旨集, 26th, 20-21 反応と合成の進歩シンポジウム講演要旨集, 26th, 20-21 反応と合成の進歩シンポジウム講演要旨集, 26th, 20-21 2000/10/27 Japanese Disclose to all
ONO HIROAKI, MIYAMURA KUMIKO, TANAKA TETSUAKI, TODA AYAKO, OISHI SHIN'YA, FUJII NOBUTAKA, TAKEMOTO YOSHIJI, IBUKA TOSHIRO 大野浩章, 宮村久美子, 田中徹明, 戸田彩子, 大石真也, 藤井信孝, 竹本佳司, 井深俊郎 ONO HIROAKI, MIYAMURA KUMIKO, TANAKA TETSUAKI, TODA AYAKO, OISHI SHIN'YA, FUJII NOBUTAKA, TAKEMOTO YOSHIJI, IBUKA TOSHIRO ジエチル亜鉛と触媒量のパラジウム(0)を用いたアレンの合成 ジエチル亜鉛と触媒量のパラジウム(0)を用いたアレンの合成 ジエチル亜鉛と触媒量のパラジウム(0)を用いたアレンの合成 反応と合成の進歩シンポジウム講演要旨集, 26th, 136-137 反応と合成の進歩シンポジウム講演要旨集, 26th, 136-137 反応と合成の進歩シンポジウム講演要旨集, 26th, 136-137 2000/10/27 Japanese Disclose to all
KAWAGUCHI MICHIYA, HOSOTANI RYO, DOI RYUICHIRO, WADA MICHIHIKO, IDA JUN, MIYAMOTO YOSHIHARU, OISHI SHIN'YA, FUJII NOBUTAKA, IMAMURA MASAYUKI 川口道也, 細谷亮, 土井隆一郎, 和田道彦, 井田純, 宮本好晴, 大石真也, 藤井信孝, 今村正之 KAWAGUCHI MICHIYA, HOSOTANI RYO, DOI RYUICHIRO, WADA MICHIHIKO, IDA JUN, MIYAMOTO YOSHIHARU, OISHI SHIN'YA, FUJII NOBUTAKA, IMAMURA MASAYUKI Integrin αVβ3を標的とした新規血管新生阻害剤の研究 Integrin αVβ3を標的とした新規血管新生阻害剤の研究 Integrin αVβ3を標的とした新規血管新生阻害剤の研究 Jpn J Cancer Res, 91, Supplement (Sept), 343 Jpn J Cancer Res, 91, Supplement (Sept), 343 Jpn J Cancer Res, 91, Supplement (Sept), 343 2000/09/01 Japanese Disclose to all
NAKAJIMA YUTAKA, HIROHASHI MARIKO, YAMASHITA MASAKI, OISHI SHIN'YA, OTAKA AKIRA, IBUKA TOSHIO, FUJII NOBUTAKA 中島豊, 広橋真理子, 山下正樹, 大石真也, 大高章, 井深俊郎, 藤井信孝 NAKAJIMA YUTAKA, HIROHASHI MARIKO, YAMASHITA MASAKI, OISHI SHIN'YA, OTAKA AKIRA, IBUKA TOSHIO, FUJII NOBUTAKA 還元的アルキル化反応によるα位に側鎖官能基を有する(E)‐アルケン型ジペプチドイソスターの合成 還元的アルキル化反応によるα位に側鎖官能基を有する(E)‐アルケン型ジペプチドイソスターの合成 還元的アルキル化反応によるα位に側鎖官能基を有する(E)‐アルケン型ジペプチドイソスターの合成 日本薬学会年会要旨集, 120th, 2, 91 日本薬学会年会要旨集, 120th, 2, 91 日本薬学会年会要旨集, 120th, 2, 91 2000/03/05 Japanese Disclose to all
OMAGARI AKANE, OISHI SHIN'YA, AKAMICHI MASAKO, OTAKA AKIRA, IBUKA TOSHIRO, NAKAJIMA HIDEKI, FUJII NOBUTAKA 大曲亜香音, 大石真也, 赤路真佐子, 大高章, 井深俊郎, 中島秀喜, 藤井信孝 OMAGARI AKANE, OISHI SHIN'YA, AKAMICHI MASAKO, OTAKA AKIRA, IBUKA TOSHIRO, NAKAJIMA HIDEKI, FUJII NOBUTAKA ペプチド性ケモカイン受容体CXCR4阻害剤T140の非ペプチド化に関する基礎研究 ペプチド性ケモカイン受容体CXCR4阻害剤T140の非ペプチド化に関する基礎研究 ペプチド性ケモカイン受容体CXCR4阻害剤T140の非ペプチド化に関する基礎研究 日本薬学会年会要旨集, 120th, 2, 132 日本薬学会年会要旨集, 120th, 2, 132 日本薬学会年会要旨集, 120th, 2, 132 2000/03/05 Japanese Disclose to all
FUJII NOBUTAKA, UMEDA YUSUKE, OISHI SHIN'YA, OTAKA AKIRA, IBUKA TOSHIRO 藤井信孝, 梅田雄介, 大石真也, 大高章, 井深俊郎 FUJII NOBUTAKA, UMEDA YUSUKE, OISHI SHIN'YA, OTAKA AKIRA, IBUKA TOSHIRO Stereoselective synthesis of protease ihibitors with transition state-mimic substructures of substrates based on Aza-Payne rearrangement. Aza‐Payne転位反応を鍵反応とする基質遷移状態模倣型酵素阻害剤の立体選択的合成法の開発と応用 Stereoselective synthesis of protease ihibitors with transition state-mimic substructures of substrates based on Aza-Payne rearrangement. メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 19th-8th, 109-110 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 19th-8th, 109-110 メディシナルケミストリーシンポジウム・日本薬学会医薬化学部会年会講演要旨集, 19th-8th, 109-110 1999/11/02 Japanese Disclose to all
OISHI SHIN'YA, HIROHASHI MARIKO, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, MURAKAMI TSUTOMU, YAMAMOTO NAOKI 大石真也, 広橋真理子, 玉村啓和, 大高章, 藤井信孝, 村上努, 山本直樹 OISHI SHIN'YA, HIROHASHI MARIKO, TAMAMURA HIROKAZU, OTAKA AKIRA, FUJII NOBUTAKA, MURAKAMI TSUTOMU, YAMAMOTO NAOKI Precise organic synthesis of Kaposi sarcoma derived HHV-8 code CC chemocaine and its activity evaluation. Kaposi肉腫由来HHV‐8コードCCケモカインの精密有機合成と活性評価 Precise organic synthesis of Kaposi sarcoma derived HHV-8 code CC chemocaine and its activity evaluation. 日本薬学会年会要旨集, 118th, 2, 73 日本薬学会年会要旨集, 118th, 2, 73 日本薬学会年会要旨集, 118th, 2, 73 1998/03 Japanese Disclose to all
N. Inoue; K. Sasagawa; K. Ikai; Y. Sasaki; J. Tomikawa; S. Oishi; N. Fujii; Y. Uenoyama; Y. Ohmori; N. Yamamoto; E. Hondo; K.-I. Maeda; H. Tsukamura N. Inoue; K. Sasagawa; K. Ikai; Y. Sasaki; J. Tomikawa; S. Oishi; N. Fujii; Y. Uenoyama; Y. Ohmori; N. Yamamoto; E. Hondo; K.-I. Maeda; H. Tsukamura Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus) Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus) Proceedings of the National Academy of Sciences of the United States of America, 108, 42, 17527-17532 , 108, 42, 17527-17532 Proceedings of the National Academy of Sciences of the United States of America, 108, 42, 17527-17532 2011/10/18 Refereed English Disclose to all
M. Baba; S.-B. Hong; N. Sharma; M.B. Warren; M.L. Nickerson; A. Iwamatsu; D. Esposito; W.K. Gillette; R.F. Hopkins III; J.L. Hartley; M. Furihata; S. Oishi; W. Zhen; T.R. Burke Jr.; W.M. Linehan; L.S. Schmidt; B. Zbar M. Baba; S.-B. Hong; N. Sharma; M.B. Warren; M.L. Nickerson; A. Iwamatsu; D. Esposito; W.K. Gillette; R.F. Hopkins III; J.L. Hartley; M. Furihata; S. Oishi; W. Zhen; T.R. Burke Jr.; W.M. Linehan; L.S. Schmidt; B. Zbar Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Proceedings of the National Academy of Sciences of the United States of America, 103, 42, 15552-15557 , 103, 42, 15552-15557 Proceedings of the National Academy of Sciences of the United States of America, 103, 42, 15552-15557 2006 Refereed English Disclose to all
P.A. Buffet; B. Gamain; C. Scheidig; D. Baruch; J.D. Smith; R. Hernandez-Rivas; B. Pouvelle; S. Oish; N. Fujii; T. Fusai; D. Parzy; L.H. Miller; J. Gysin; A. Scherf P.A. Buffet; B. Gamain; C. Scheidig; D. Baruch; J.D. Smith; R. Hernandez-Rivas; B. Pouvelle; S. Oish; N. Fujii; T. Fusai; D. Parzy; L.H. Miller; J. Gysin; A. Scherf Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection Proceedings of the National Academy of Sciences of the United States of America, 96, 22, 12743-12748 , 96, 22, 12743-12748 Proceedings of the National Academy of Sciences of the United States of America, 96, 22, 12743-12748 1999/10/26 Refereed English Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
大野浩章、大石真也 大野浩章、大石真也 新しい反応が加速する創薬研究 新しい反応が加速する創薬研究 Biophilia(アドスリー) Biophilia(アドスリー) 2017/04 Contributor Disclose to all
大石真也 他 大石真也 他 スタンダード薬学シリーズⅡ・化学系薬学Ⅱ(SBO24,25) スタンダード薬学シリーズⅡ・化学系薬学Ⅱ(SBO24,25) 東京化学同人 東京化学同人 2016/03 Contributor Disclose to all
大石真也 他 大石真也 他 有機合成ハンドブック第2版 結晶と沪過 有機合成ハンドブック第2版 結晶と沪過 丸善出版 丸善出版 2015/11 Contributor Disclose to all
前多敬一郎、大石真也、束村博子、上野山賀久、大蔵聡、松田二子 前多敬一郎、大石真也、束村博子、上野山賀久、大蔵聡、松田二子 新たな中枢性繁殖制御剤のシーズ:KNDyニューロン 新たな中枢性繁殖制御剤のシーズ:KNDyニューロン MPアグロジャーナル(MPアグロ) MPアグロジャーナル(MPアグロ) 2014/01 Contributor Disclose to all
大石真也、藤井信孝 大石真也、藤井信孝 ウイルスの変異に学ぶ抗HIV活性ペプチドのデザイン ウイルスの変異に学ぶ抗HIV活性ペプチドのデザイン ペプチド医薬の最前線(シーエムシー出版) ペプチド医薬の最前線(シーエムシー出版) 2012/11 Contributor Disclose to all
大石 真也 大石 真也 ケミカルバイオロジー研究を基盤にした抗癌剤の創出:KSP阻害剤の創出 ケミカルバイオロジー研究を基盤にした抗癌剤の創出:KSP阻害剤の創出 遺伝子医学MOOK20 ナノバイオ技術と最新創薬応用研究 遺伝子医学MOOK20 ナノバイオ技術と最新創薬応用研究 2012 Japanese Disclose to all
大石 真也 大石 真也 ハイスループットスクリーニング ハイスループットスクリーニング インシリコ創薬科学(3.3節・京都廣川書店) インシリコ創薬科学(3.3節・京都廣川書店) 2008 Japanese Disclose to all
大石 真也 大石 真也 化合物ライブラリー 化合物ライブラリー インシリコ創薬科学(3.2節・京都廣川書店) インシリコ創薬科学(3.2節・京都廣川書店) 2008 Japanese Disclose to all
大石 真也 大石 真也 ペプチドをリードとした創薬 ペプチドをリードとした創薬 蛋白質 核酸 酵素 増刊 ケミカルバイオロジー 蛋白質 核酸 酵素 増刊 ケミカルバイオロジー 2007 Japanese Disclose to all
大石 真也 大石 真也 ケミカルバイオロジーを基盤とするペプチド創薬 ケミカルバイオロジーを基盤とするペプチド創薬 遺伝子医学MOOK8 ペプチドと創薬 遺伝子医学MOOK8 ペプチドと創薬 2007 Japanese Disclose to all
大石 真也 大石 真也 プロテオミクスを基盤とするケミカルバイオロジー─情報から制御へ プロテオミクスを基盤とするケミカルバイオロジー─情報から制御へ バイオニクス バイオニクス 2006 Japanese Disclose to all

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Patents
Inventor(s) Inventor(s) (Japanese) Inventor(s) (English) Title Title(Japanese) Title(English) Stage Patent number Date Disclose
掛谷 秀昭, 服部 明, 高須 康明, 藤井 信孝, 大石 真也, 小嶋 聡一, 原 詳子 掛谷 秀昭, 服部 明, 高須 康明, 藤井 信孝, 大石 真也, 小嶋 聡一, 原 詳子 TGF−βシグナル伝達阻害剤 TGF−βシグナル伝達阻害剤 特許登録 特許5846527 2015/12/04 Disclose to all
藤井 信孝, 大石 真也, 富田 健嗣 藤井 信孝, 大石 真也, 富田 健嗣 メタスチン誘導体およびその用途 メタスチン誘導体およびその用途 特許登録 特許第5700641号 2015/02/27 Disclose to all
掛谷 秀昭, 服部 明, 高須 康明, 藤井 信孝, 大石 真也, 小嶋 聡一, 原 詳子 掛谷 秀昭, 服部 明, 高須 康明, 藤井 信孝, 大石 真也, 小嶋 聡一, 原 詳子 TGF−βシグナル伝達阻害剤 TGF−βシグナル伝達阻害剤 特許登録 US8,772,297 2014/07/08 Disclose to all
藤井 信孝, 大石 真也, 富田 健嗣 藤井 信孝, 大石 真也, 富田 健嗣 メタスチン誘導体およびその用途 メタスチン誘導体およびその用途 特許登録 US8,592,379 2013/11/26 Disclose to all
藤井 信孝, 大石 真也, 富田 健嗣, 新居田 歩 藤井 信孝, 大石 真也, 富田 健嗣, 新居田 歩 GPR54アゴニスト活性を有する新規化合物 GPR54アゴニスト活性を有する新規化合物 特許登録 特許第5279021号 2013/05/31 Disclose to all
藤井 信孝, 大石 真也, 富田 健嗣, 新居田 歩 藤井 信孝, 大石 真也, 富田 健嗣, 新居田 歩 GPR54アゴニスト活性を有する新規化合物 GPR54アゴニスト活性を有する新規化合物 特許登録 US8,183,212 2012/05/22 Disclose to all
藤井 信孝, 土井 隆一郎, 大石 真也 藤井 信孝, 土井 隆一郎, 大石 真也 メタスチン誘導体およびその使用 メタスチン誘導体およびその使用 特許登録 特許第4335910号 2009/07/03 Disclose to all
藤井 信孝, 土井 隆一郎, 大石 真也 藤井 信孝, 土井 隆一郎, 大石 真也 メタスチン誘導体およびその使用 メタスチン誘導体およびその使用 特許登録 US6,800,811 2004/10/05 Disclose to all
大石真也、藤井信孝、大野浩章、桑井真司、若林嘉浩、山村崇 大石真也、藤井信孝、大野浩章、桑井真司、若林嘉浩、山村崇 新規NK3受容体アゴニスト 新規NK3受容体アゴニスト 特許公開 WO2017-073764 2017/05/04 Disclose to all
大石真也、大野浩章、藤井信孝、山本昴輝 大石真也、大野浩章、藤井信孝、山本昴輝 新規な化合物、薬剤およびNK3受容体拮抗剤 新規な化合物、薬剤およびNK3受容体拮抗剤 特許公開 特開2017-081888 2017/05/18 Disclose to all
松岡雅雄、志村和也、藤井信孝、大野浩章、大石真也、水原司、岡崎志穂 松岡雅雄、志村和也、藤井信孝、大野浩章、大石真也、水原司、岡崎志穂 ベンゾイソチアゾロピリミジン誘導体またはその塩、およびウイルス感染阻害剤ならびに医薬品 ベンゾイソチアゾロピリミジン誘導体またはその塩、およびウイルス感染阻害剤ならびに医薬品 特許公開 WO2016-056606 Disclose to all
松田道行、齋藤勝広、大石真也、小松直貴、青木一洋 松田道行、齋藤勝広、大石真也、小松直貴、青木一洋 Ras活性阻害薬及びその用途 Ras活性阻害薬及びその用途 特許公開 WO2015-182625 2015/12/03 Disclose to all
藤井信孝、大野浩章、大石真也、三須良介、山田愛、山本昂輝、岡村裕昭、山村崇 藤井信孝、大野浩章、大石真也、三須良介、山田愛、山本昂輝、岡村裕昭、山村崇 新規NK3受容体アゴニスト 新規NK3受容体アゴニスト 特許公開 WO2015-083816 2015/06/11 Disclose to all
藤井信孝、大野浩章、大石真也、久保達彦、黒柳友子、ニコラ モンパ、ニコラウス ヘヴェカー 藤井信孝、大野浩章、大石真也、久保達彦、黒柳友子、ニコラ モンパ、ニコラウス ヘヴェカー CXCR7結合剤およびCXCR7結合剤を含有する医薬組成物 CXCR7結合剤およびCXCR7結合剤を含有する医薬組成物 特許公開 特開2016-065018 2016/04/28 Disclose to all
藤井信孝、大野浩章、大石真也、野口太朗、三須良介、岡村裕昭、山村崇 藤井信孝、大野浩章、大石真也、野口太朗、三須良介、岡村裕昭、山村崇 新規NK3受容体アゴニスト 新規NK3受容体アゴニスト 特許公開 WO2014-061772 2014/04/24 Disclose to all
前田 英樹, 加藤 貴之, 松岡 雅雄, 志村 和也, 藤井 信孝, 大野 浩章, 大石 真也, 水原 司 前田 英樹, 加藤 貴之, 松岡 雅雄, 志村 和也, 藤井 信孝, 大野 浩章, 大石 真也, 水原 司 ピリミドベンゾチアジン−6−イミン誘導体またはその塩を含有するウイルス感染症の治療および/または予防のための薬剤 ピリミドベンゾチアジン−6−イミン誘導体またはその塩を含有するウイルス感染症の治療および/または予防のための薬剤 特許登録 特許5807308 Disclose to all
辻本 豪三, 平澤 明, 村田 克美, 藤井 信孝, 大野 浩章, 大石 真也, 鈴木 大和, ゾンイェ ホウ, 仲西 功, 木下 誉富, 高倉 喜信, 西川 元也 辻本 豪三, 平澤 明, 村田 克美, 藤井 信孝, 大野 浩章, 大石 真也, 鈴木 大和, ゾンイェ ホウ, 仲西 功, 木下 誉富, 高倉 喜信, 西川 元也 キナーゼ阻害剤 キナーゼ阻害剤 特許公開 WO2012-121168 2012/09/13 Disclose to all
藤井 信孝, 大野 浩章, 大石 真也, 井ノ口 恵利子, 久保 達彦, 松岡 雅雄, 志村 和也 藤井 信孝, 大野 浩章, 大石 真也, 井ノ口 恵利子, 久保 達彦, 松岡 雅雄, 志村 和也 新規ケモカイン受容体拮抗剤 新規ケモカイン受容体拮抗剤 特許公開 WO2012-118124 2012/09/07 Disclose to all
梶原 一美, 田中 智子, 秦 洋二, 堤 浩子, 藤井 信孝, 松岡 雅雄, 大石 真也 梶原 一美, 田中 智子, 秦 洋二, 堤 浩子, 藤井 信孝, 松岡 雅雄, 大石 真也 酵母によるN36結合ペプチドの製造方法 酵母によるN36結合ペプチドの製造方法 特許公開 特開2011-177135 2011/09/15 Disclose to all
坂東 弘樹, 堤 浩子, 秦 洋二, 梶原 一美, 藤井 信孝, 松岡 雅雄, 大石 真也 坂東 弘樹, 堤 浩子, 秦 洋二, 梶原 一美, 藤井 信孝, 松岡 雅雄, 大石 真也 麹菌によるN36結合ペプチドの生産方法 麹菌によるN36結合ペプチドの生産方法 特許公開 特開2011-167076 2011/09/01 Disclose to all
藤井信孝、小川修、西山博之、大野浩章、大石真也、渡部敏明、竹内智起、浅井章良、澤田潤一 藤井信孝、小川修、西山博之、大野浩章、大石真也、渡部敏明、竹内智起、浅井章良、澤田潤一 Eg5阻害剤 Eg5阻害剤 特許公開 WO2010-073719 2010/07/01 Disclose to all
藤井 信孝, 松岡 雅雄, 児玉 栄一, 大石 真也, 田中 理紀, 秦 洋二, 堤 浩子, 梶原 一美, 常磐 礼 藤井 信孝, 松岡 雅雄, 児玉 栄一, 大石 真也, 田中 理紀, 秦 洋二, 堤 浩子, 梶原 一美, 常磐 礼 修飾ペプチド及びその製造方法 修飾ペプチド及びその製造方法 特許公開 特開2011-020926 2011/02/03 Disclose to all
浅井 章良, 澤田 潤一, 松野 研司, 小郷 尚久, 藤井 信考, 大石 真也 浅井 章良, 澤田 潤一, 松野 研司, 小郷 尚久, 藤井 信考, 大石 真也 Eg5阻害剤および該化合物を含有してなる細胞増殖性疾患治療薬 Eg5阻害剤および該化合物を含有してなる細胞増殖性疾患治療薬 特許公開 WO2008-114505 2008/09/25 Disclose to all
藤井 信孝, 大石 真也, 松岡 雅雄, 児玉 栄一 藤井 信孝, 大石 真也, 松岡 雅雄, 児玉 栄一 抗HIV剤 抗HIV剤 特許公開 WO2008-050830 2008/05/02 Disclose to all
堤 浩子, 石田 博樹, 久田 博元, 水本 真紀子, 秦 洋二, 藤井 信孝, 松岡 雅雄, 児玉 栄一, 大石 真也 堤 浩子, 石田 博樹, 久田 博元, 水本 真紀子, 秦 洋二, 藤井 信孝, 松岡 雅雄, 児玉 栄一, 大石 真也 N36結合ペプチドの製造方法 N36結合ペプチドの製造方法 特許公開 特開2008-029239 2008/02/14 Disclose to all
藤井信孝、大野浩章、大石真也、竹内智起、浅井章良、澤田潤一 藤井信孝、大野浩章、大石真也、竹内智起、浅井章良、澤田潤一 Eg5阻害剤 Eg5阻害剤 特許公開 WO2014-174745 2014/10/30 Disclose to all

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Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
日本薬学会近畿支部奨励賞 日本薬学会 2003/01/
日本薬学会奨励賞 日本薬学会 2009/03/
有機合成化学協会帝人ファーマ研究企画賞 有機合成化学協会 2012/12/
External funds, competitive funds and Grants-in-Aid for Scientific Research(kaken)
Type Position Title(Japanese) Title(English) Period
基盤研究(B) Representative 生体分子の鏡映変換による医薬品探索技術の開発と応用 2018/04/01-2019/03/31
基盤研究(B) Representative 鏡像体タンパク質を用いた医薬品探索技術の開発と実証 2015/04/01-2018/03/31
挑戦的萌芽研究 Assignment 新しいスキャフォルド分子の生成機構とその生理的意義 2012/04/01-2013/03/31
挑戦的萌芽研究 Representative ペプチド性医薬品創製のための新概念の構築と検証 2012/04/01-2015/03/31
基盤研究(B) Assignment 活性動態の理解に基づいた脱ユビキチン化酵素の機能解明 2011/04/01-2013/03/31
若手研究(A) Representative 性ホルモン分泌調節における神経ペプチド受容体機能制御の分子基盤の解明 2011/04/01-2015/03/31
厚生労働科研費 Assignment 新規標的に対する小分子化合物を基盤とした抗HIV化学療法剤の開発 2010/04/01-2012/03/31
特定領域研究 Assignment GPCR周辺の細胞外環境解明のためのケミカルプローブの創出と応用 2008/04/01-2010/03/31
特定領域研究 Assignment 多重標的創薬概念に基づくがん化学療法の新機軸 2008/04/01-2010/03/31
若手研究(B) Representative 難解析性タンパク質リガンドの探索のための新規化合物評価系の構築と応用 2008/04/01-2010/03/31
厚生労働科研費 Assignment HIV吸着・膜融合過程を標的とする多剤耐性克服型HIV化学療法剤の開発 2007/04/01-2010/03/31
特定領域研究 Assignment 有機化学を基盤にしたGPCR細胞外環境のケミカルバイオロジー研究 2006/04/01-2008/03/31
基盤研究(A)(一般) Assignment 7回膜貫通型受容体を分子標的とする創薬基盤の革新 2005/04/01-2008/03/31
基盤研究(B)(一般) Assignment ガン治療効果予測を可能とする指標および放射性薬剤の開発-酸素効果を中心として 2005/04/01-2008/03/31
若手研究(B) Representative 蛋白質-蛋白質相互作用阻害剤の探索を指向した新規化合物評価システムの開発研究 2005/04/01-2008/03/31
厚生労働科研費 Assignment HIV融合過程を標的とする耐性克服型新規治療薬の開発 2004/04/01-2007/03/31
特別研究員奨励費 Representative 光学活性アジリジンを合成素子とするペプチドイソスターの立体選択的合成法の開発 2001/04/01-2003/03/31

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Non-external, competitive funds or grants other than grants-in-aid for Scientific research (kaken)
System Main person Title(Japanese) Title(English) Period
平成30年度 京都大学医学部附属病院臨床研究総合センター 橋渡し研究戦略的推進プログラム シーズA 大石真也 環状デプシペプチドcoibamide Aをリードとする分子標的薬の開発 2018/04/01-2019/03/31
平成29年度 京都大学医学部附属病院臨床研究総合センター 橋渡し研究支援プログラム シーズA 大石真也 ウイルスゲノム情報に基づく麻疹ウイルス侵入阻害剤の創製 2017/04/01-2018/03/31
公益財団法人加藤記念バイオサイエンス振興財団 研究助成金 大石真也 化学合成タンパク質を利用した天然物の鏡像体からの医薬品探索研究 2017/03/21-2019/12/31
公益財団法人持田記念医学薬学振興財団 研究助成金 大石真也 天然物・天然資源の鏡像体化合物の活用を可能にする医薬品探索技術の開発 2016/11/22-2017/12/31
AMED次世代がん医療創生研究事業 松岡雅雄 免疫抑制性受容体TIGIT阻害活性を有する小分子化合物の開発研究 2016/04/01-2019/03/31
公益財団法人東京生化学研究会 研究奨励金 大石真也 化学合成タンパク質を活用した天然物の鏡像体からの医薬品探索 2016/02/18-2017/03/31
公益財団法人鈴木謙三医科学応用研究財団 平成27年度調査研究助成 大石真也 ケモカイン受容体CXCR7リガンドの創製と副腎機能調節剤への応用 2015/12/15-2016/12/31
武田科学振興財団・薬学系研究奨励継続助成 大石真也 ペプチド性二次代謝産物の効率的合成法の開発と創薬展開 2015/10/01-2018/03/31
農林水産省・農林水産業・食品産業科学技術研究推進事業(シーズ創出ステージ) 前多敬一郎 新規な繁殖中枢制御剤開発による家畜繁殖技術と野生害獣個体数抑制技術の革新 2012/04/01-2014/03/31
武田科学振興財団・薬学系研究奨励 大石真也 ペプチド性二次代謝産物の効率的合成法の開発と創薬展開 2012/04/01-2013/03/31
上原記念生命科学財団・研究奨励金 大石真也 抗腫瘍活性ペプチドの全合成とその応用 2012/04/01-2014/03/31
有機合成化学協会 帝人ファーマ研究企画賞 大石真也 アミド結合の修飾基の開発とペプチド性天然物の合成への応用 2011/04/01-2018/03/31

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Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
有機化学V(有機合成論) 前期 薬学部 2011/04-2012/03
新薬論 後期 薬学部 2011/04-2012/03
有機化学3(創薬化学) 前期 薬学部 2011/04-2012/03
医薬品化学・新薬論 後期 薬学部 2011/04-2012/03
創薬リード探索技術 Drug Discovery & Development II: 後期不定 薬学研究科 2011/04-2012/03
創薬有機化学エクササイズ 後期 薬学部 2011/04-2012/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2011/04-2012/03
リード化合物探索スキル(秋入学用) Skill Development for Lead Discovery 後期前期 薬学研究科 2011/04-2012/03
くすりの化学 Organic Chemistry of Pharmaceuticals 前期 全学共通科目 2011/04-2012/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2011/04-2012/03
医薬創成研究プロジェクト特論 Advanced Drug Discovery & Development I 前期不定 薬学研究科 2011/04-2012/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems 通年不定 薬学研究科 2011/04-2012/03
システム生物学・医薬創成系コンテンツ制作(秋入学) Advanced Methods in Systems 後期前期 薬学研究科 2011/04-2012/03
システム生物学・医薬創成系研究 Research in Systems 通年不定 薬学研究科 2011/04-2012/03
システム生物学・医薬創成系研究(秋入学用) Research in Systems 後期前期 薬学研究科 2011/04-2012/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2011/04-2012/03
薬学専門実習II 前期 薬学部 2011/04-2012/03
薬学専門実習2 前期 薬学部 2011/04-2012/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2012/04-2013/03
創薬有機化学エクササイズ Organic Chemistry Exercise 後期 薬学部 2012/04-2013/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2012/04-2013/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2012/04-2013/03
医薬品化学・新薬論 Medicinal Chemistry and Drug Discovery 後期 薬学部 2012/04-2013/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2012/04-2013/03
新薬論 Discovery and Developmennt of New Drugs 後期 薬学部 2012/04-2013/03
有機化学3(創薬化学) Organic Chemistry 3 (Medicinal Chemistry) 前期 薬学部 2012/04-2013/03
有機化学V(有機合成論) Synthetic Organic Chemistry 前期 薬学部 2012/04-2013/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2012/04-2013/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2012/04-2013/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2012/04-2013/03
薬学専門実習II Pharmaceutical Laboratory II:Organic Chemistry 前期 薬学部 2012/04-2013/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2012/04-2013/03
医薬品化学・新薬論 Medicinal Chemistry and Drug Discovery 後期 薬学部 2013/04-2014/03
創薬有機化学エクササイズ Organic Chemistry Exercise 後期 薬学部 2013/04-2014/03
有機化学3 Organic Chemistry 3 前期 薬学部 2013/04-2014/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2013/04-2014/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2013/04-2014/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2013/04-2014/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2013/04-2014/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2013/04-2014/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2013/04-2014/03
博士後期課程特論 doctoral program 前期集中 薬学研究科 2013/04-2014/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2013/04-2014/03
くすりの化学 Organic Chemistry of Pharmaceuticals 前期 全学共通科目 2013/04-2014/03
医薬品化学・新薬論 Medicinal Chemistry and Drug Discovery 後期 薬学部 2014/04-2015/03
創薬有機化学エクササイズ Organic Chemistry Exercise 後期 薬学部 2014/04-2015/03
有機化学3 Organic Chemistry 3 前期 薬学部 2014/04-2015/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2014/04-2015/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2014/04-2015/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2014/04-2015/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2014/04-2015/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2014/04-2015/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2014/04-2015/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2014/04-2015/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2014/04-2015/03
くすりの化学 Organic Chemistry of Pharmaceuticals 前期 全学共通科目 2014/04-2015/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2015/04-2016/03
くすりの化学 Organic Chemistry of Pharmaceuticals 前期 全学共通科目 2015/04-2016/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2015/04-2016/03
医薬品化学・新薬論 Medicinal Chemistry and Drug Discovery 後期 薬学部 2015/04-2016/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2015/04-2016/03
有機化学3 Organic Chemistry 3 前期 薬学部 2015/04-2016/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2015/04-2016/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2015/04-2016/03
薬学倫理・概論 An Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2015/04-2016/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2015/04-2016/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2016/04-2017/03
創薬有機化学エクササイズ2 Organic Chemistry Exercise 2 後期 薬学部 2016/04-2017/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2016/04-2017/03
医薬創成プロセス概論 Introduction to Drug Discovery Sciences 前期不定 薬学研究科 2016/04-2017/03
医薬品化学 Medicinal Chemistry 前期 薬学部 2016/04-2017/03
医薬品開発プロジェクト演習I Pharmaceutical R&D Exercise I 前期 薬学部 2016/04-2017/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2016/04-2017/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2016/04-2017/03
「薬の世界」入門 Introduction to Pharmaceutical Sciences and Ethics 前期 全学共通科目 2016/04-2017/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2016/04-2017/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2017/04-2018/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2017/04-2018/03
医薬品化学 Medicinal Chemistry 前期 薬学部 2017/04-2018/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2017/04-2018/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2017/04-2018/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2017/04-2018/03
創薬リード探索技術 Drug Discovery & Development II: Lead Discovery Technology 後期不定 薬学研究科 2018/04-2019/03
創薬有機化学概論 Introduction to Organic Chemistry for Drug Discovery 前期不定 薬学研究科 2018/04-2019/03
リード化合物探索スキル Skill Development for Lead Discovery 通年不定 薬学研究科 2018/04-2019/03
医薬品化学 Medicinal Chemistry 前期 薬学部 2018/04-2019/03
基盤有機化学特論II Advanced Basic Organic Chemistry II 後期不定 薬学研究科 2018/04-2019/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 後期前期 薬学研究科 2018/04-2019/03
システム生物学・医薬創成系コンテンツ制作 Advanced Methods in Systems Biology & Drug Discovery 通年不定 薬学研究科 2018/04-2019/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 後期前期 薬学研究科 2018/04-2019/03
システム生物学・医薬創成系研究 Research in Systems Biology & Drug Dicovery 通年不定 薬学研究科 2018/04-2019/03
薬学専門実習2 Pharmaceutical Laboratory 2 : Organic Chemistry 前期 薬学部 2018/04-2019/03

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School management (title, position)
Title Period
国際高等教育院 企画評価専門委員会 人文・社会科学部会1 委員 2016/05/01-2017/04/30
環境安全保全機構環境管理専門委員会(有機) 2017/07/01-2019/03/31
化学物質専門委員会委員 2017/04/01-2019/03/31
Faculty management (title, position)
Title Period
ホームページ広報委員会 委員 2012/04/01-
図書委員会 委員 2012/04/01-2018/03/31
動物実験委員会 委員 2014/12/01-
環境・安全衛生委員会 委員 2015/04/01-
情報システム委員会 委員 2011/04/01-
RI管理委員会 委員 2011/04/01-
教務委員会 2017/04/01-
Other activities (public organizations)
Committee(Japanese) Committee(English) Title Organization name Period
農林水産省・食品産業科学技術研究推進事業 1次審査専門評価委員 農林水産・食品産業技術振興協会 2017/02/01-2018/03/30
京都市ベンチャー企業目利き委員会 調査専門委員 京都市 2015/12/24-2016/03/31