WOLTJEN KNUT

Last Update: 2015/06/30 20:49:03

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Name(Kanji/Kana/Abecedarium Latinum)
WOLTJEN KNUT/ウォルツェン クヌート/Woltjen, Knut
Primary Affiliation(Org1/Job title)
iPS細胞研究所/Associate Professor
Contact Address
Type Address(Japanese) Address(English)
Office 〒606-8507 京都市 左京区 聖護院川原町53 日本 53 Kawahara-cho, Shogoin, Sakyo-ku Kyoto 〒606-8507 Japan
Phone
Type Number
Office 075-366-7000
Academic Degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
Ph.D. University of Calgary
Language of Instruction
Language
English
Japanese
Personal Website(s) (URL(s))
URL
http://www.cira.kyoto-u.ac.jp/woltjen/
researchmap URL
https://researchmap.jp/7000008096
Fields of research (key words)
Key words(Japanese) Key words(English)
DNA recombination, stem cell biology, regenerative medicine, genomics
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. Stem cell reports, 12, 5, 1113-1128 Stem cell reports, 12, 5, 1113-1128 Stem cell reports, 12, 5, 1113-1128 2019/05 Refereed Disclose to all
Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Cancer science, 110, 3, 926-938 Cancer science, 110, 3, 926-938 Cancer science, 110, 3, 926-938 2019/03 Refereed Disclose to all
Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. Stem cell reports, 12, 2, 319-332 Stem cell reports, 12, 2, 319-332 Stem cell reports, 12, 2, 319-332 2019/02 Refereed Disclose to all
Woltjen K, Bortvin A Woltjen K, Bortvin A Woltjen K, Bortvin A Editorial overview: Embroidering the canvas of life. Editorial overview: Embroidering the canvas of life. Editorial overview: Embroidering the canvas of life. Current opinion in genetics & development, 52, ii-iv Current opinion in genetics & development, 52, ii-iv Current opinion in genetics & development, 52, ii-iv 2018/10 Refereed Disclose to all
Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y In vivo reprogramming drives Kras-induced cancer development. In vivo reprogramming drives Kras-induced cancer development. In vivo reprogramming drives Kras-induced cancer development. Nature communications, 9, 1, 2081 Nature communications, 9, 1, 2081 Nature communications, 9, 1, 2081 2018/05 Refereed Disclose to all
Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Nature communications, 9, 1, 1387 Nature communications, 9, 1, 1387 Nature communications, 9, 1, 1387 2018/04 Refereed Disclose to all
Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K Microhomology-assisted scarless genome editing in human iPSCs. Microhomology-assisted scarless genome editing in human iPSCs. Microhomology-assisted scarless genome editing in human iPSCs. Nature communications, 9, 1, 939 Nature communications, 9, 1, 939 Nature communications, 9, 1, 939 2018/03 Refereed Disclose to all
Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. Cell reports, 21, 8, 2304-2312 Cell reports, 21, 8, 2304-2312 Cell reports, 21, 8, 2304-2312 2017/11 Refereed Disclose to all
Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, Nakaki F, Nagaoka S, Woltjen K, Hotta A, Yamamoto T, Saitou M Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, Nakaki F, Nagaoka S, Woltjen K, Hotta A, Yamamoto T, Saitou M Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, Nakaki F, Nagaoka S, Woltjen K, Hotta A, Yamamoto T, Saitou M Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell stem cell, 21, 4, 517-532.e5 Cell stem cell, 21, 4, 517-532.e5 Cell stem cell, 21, 4, 517-532.e5 2017/10 Refereed Disclose to all
Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N Beta-cell replacement strategies for diabetes. Beta-cell replacement strategies for diabetes. Beta-cell replacement strategies for diabetes. Journal of diabetes investigation Journal of diabetes investigation Journal of diabetes investigation 2017/10 Refereed Disclose to all
Hirosawa M, Fujita Y, Parr CJC, Hayashi K, Kashida S, Hotta A, Woltjen K, Saito H Hirosawa M, Fujita Y, Parr CJC, Hayashi K, Kashida S, Hotta A, Woltjen K, Saito H Hirosawa M, Fujita Y, Parr CJC, Hayashi K, Kashida S, Hotta A, Woltjen K, Saito H Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch. Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch. Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch. Nucleic acids research, 45, 13, e118 Nucleic acids research, 45, 13, e118 Nucleic acids research, 45, 13, e118 2017/07 Refereed Disclose to all
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science translational medicine, 9, 391 Science translational medicine, 9, 391 Science translational medicine, 9, 391 2017/05 Refereed Disclose to all
Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser JE, Yamada Y, Yamanaka S, Yamamoto T Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser JE, Yamada Y, Yamanaka S, Yamamoto T Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser JE, Yamada Y, Yamanaka S, Yamamoto T Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency. Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency. Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency. Cell metabolism, 25, 5, 1103-1117.e6 Cell metabolism, 25, 5, 1103-1117.e6 Cell metabolism, 25, 5, 1103-1117.e6 2017/05 Refereed Disclose to all
Hashimoto K, Yamada Y, Semi K, Yagi M, Tanaka A, Itakura F, Aoki H, Kunisada T, Woltjen K, Haga H, Sakai Y, Yamamoto T, Yamada Y Hashimoto K, Yamada Y, Semi K, Yagi M, Tanaka A, Itakura F, Aoki H, Kunisada T, Woltjen K, Haga H, Sakai Y, Yamamoto T, Yamada Y Hashimoto K, Yamada Y, Semi K, Yagi M, Tanaka A, Itakura F, Aoki H, Kunisada T, Woltjen K, Haga H, Sakai Y, Yamamoto T, Yamada Y Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior. Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior. Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior. Proceedings of the National Academy of Sciences of the United States of America, 114, 4, 758-763 Proceedings of the National Academy of Sciences of the United States of America, 114, 4, 758-763 Proceedings of the National Academy of Sciences of the United States of America, 114, 4, 758-763 2017/01 Refereed Disclose to all
Woltjen K, Yamamoto T, Kokubu C, Takeda J Woltjen K, Yamamoto T, Kokubu C, Takeda J Woltjen K, Yamamoto T, Kokubu C, Takeda J Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara. Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara. Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara. Genes to cells : devoted to molecular & cellular mechanisms, 21, 5, 392-395 Genes to cells : devoted to molecular & cellular mechanisms, 21, 5, 392-395 Genes to cells : devoted to molecular & cellular mechanisms, 21, 5, 392-395 2016/05 Refereed Disclose to all
Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Xiang L, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Xiang L, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Xiang L, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives. Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives. Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives. Methods (San Diego, Calif.), 101, 43-55 Methods (San Diego, Calif.), 101, 43-55 Methods (San Diego, Calif.), 101, 43-55 2016/05 Refereed Disclose to all
Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development. An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development. An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development. Stem cell reports, 6, 4, 592-606 Stem cell reports, 6, 4, 592-606 Stem cell reports, 6, 4, 592-606 2016/04 Refereed Disclose to all
Woltjen K, Kim SI, Nagy A Woltjen K, Kim SI, Nagy A Woltjen K, Kim SI, Nagy A The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. Methods in molecular biology (Clifton, N.J.), 1357, 1-22 Methods in molecular biology (Clifton, N.J.), 1357, 1-22 Methods in molecular biology (Clifton, N.J.), 1357, 1-22 2016 Refereed Disclose to all
Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K Reprogramming Roadblocks Are System Dependent. Reprogramming Roadblocks Are System Dependent. Reprogramming Roadblocks Are System Dependent. Stem cell reports, 5, 3, 350-364 Stem cell reports, 5, 3, 350-364 Stem cell reports, 5, 3, 350-364 2015/09 Refereed Disclose to all
Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 Cell stem cell, 17, 2, 178-194 2015/08 Refereed Disclose to all
Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. WOLTJEN KNUT Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. KLF4 N-terminal variance modulates induced reprogramming to pluripotency. KLF4 N-terminal variance modulates induced reprogramming to pluripotency. KLF4 N-terminal variance modulates induced reprogramming to pluripotency. Stem Cell Reports, 4, 4, 727-743 Stem Cell Reports, 4, 4, 727-743 Stem Cell Reports, 4, 4, 727-743 2015/04 Refereed English Research paper(scientific journal) Disclose to all
Matsuda M, Koga M, Woltjen K, Nishida E, Ebisuya M. WOLTJEN KNUT Matsuda M, Koga M, Woltjen K, Nishida E, Ebisuya M. Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. Nature Communications, 6, 6195 Nature Communications, 6, 6195 Nature Communications, 6, 6195 2015 Refereed English Research paper(scientific journal) Disclose to all
Shoji E, Woltjen K, Sakurai H. WOLTJEN KNUT Shoji E, Woltjen K, Sakurai H. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Methods in Molecular Biology, 1353, 89-99 Methods in Molecular Biology, 1353, 89-99 Methods in Molecular Biology, 1353, 89-99 2015 Refereed English Research paper(scientific journal) Disclose to all
Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K WOLTJEN KNUT Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Methods in Molecular Biology, 1357, 111-131 Methods in Molecular Biology, 1357, 111-131 Methods in Molecular Biology, 1357, 111-131 2015 Refereed English Research paper(scientific journal) Disclose to all
Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T Jr, Toguchida J Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T Jr, Toguchida J Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T Jr, Toguchida J SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier. SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier. SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier. PloS one, 10, 11, e0142991 PloS one, 10, 11, e0142991 PloS one, 10, 11, e0142991 2015 Refereed Disclose to all
Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T Jr, Okamoto T, Matsuda S, Toguchida J Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. PloS one, 10, 7, e0131998 PloS one, 10, 7, e0131998 PloS one, 10, 7, e0131998 2015 Refereed Disclose to all
K. Ohnishi; K. Semi; T. Yamamoto; M. Shimizu; A. Tanaka; K. Mitsunaga; K. Okita; K. Osafune; Y. Arioka; T. Maeda; H. Soejima; H. Moriwaki; S. Yamanaka; K. Woltjen; Y. Yamada Ohnishi K, Semi K, Yamamoto T, Shimizu M, Tanaka A, Mitsunaga K, Okita K, Osafune K, Arioka Y, Maeda T, Soejima H, Moriwaki H, Yamanaka S, Woltjen K, Yamada Y K. Ohnishi; K. Semi; T. Yamamoto; M. Shimizu; A. Tanaka; K. Mitsunaga; K. Okita; K. Osafune; Y. Arioka; T. Maeda; H. Soejima; H. Moriwaki; S. Yamanaka; K. Woltjen; Y. Yamada Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation. Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation Cell, 156, 4, 663-677 Cell, 156, 4, 663-677 Cell, 156, 4, 663-677 2014/02 Refereed English Disclose to all
T. Sakuma; K. Woltjen Sakuma T, Woltjen K T. Sakuma; K. Woltjen Nuclease-mediated genome editing: At the front-line of functional genomics technology Nuclease-mediated genome editing: At the front-line of functional genomics technology. Nuclease-mediated genome editing: At the front-line of functional genomics technology Development Growth and Differentiation, 56, 1, 2-13 Development, growth & differentiation, 56, 1, 2-13 Development Growth and Differentiation, 56, 1, 2-13 2014/01 Refereed English Disclose to all
Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD. WOLTJEN KNUT Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell, 13, 5, 564-576 Cell Stem Cell, 13, 5, 564-576 Cell Stem Cell, 13, 5, 564-576 2013/11 Refereed English Research paper(scientific journal) Disclose to all
T. Sakuma; S. Hosoi; K. Woltjen; K.-I. Suzuki; K. Kashiwagi; H. Wada; H. Ochiai; T. Miyamoto; N. Kawai; Y. Sasakura; S. Matsuura; Y. Okada; A. Kawahara; S. Hayashi; T. Yamamoto Sakuma T, Hosoi S, Woltjen K, Suzuki K, Kashiwagi K, Wada H, Ochiai H, Miyamoto T, Kawai N, Sasakura Y, Matsuura S, Okada Y, Kawahara A, Hayashi S, Yamamoto T T. Sakuma; S. Hosoi; K. Woltjen; K.-I. Suzuki; K. Kashiwagi; H. Wada; H. Ochiai; T. Miyamoto; N. Kawai; Y. Sasakura; S. Matsuura; Y. Okada; A. Kawahara; S. Hayashi; T. Yamamoto Efficient TALEN construction and evaluation methods for human cell and animal applications Efficient TALEN construction and evaluation methods for human cell and animal applications. Efficient TALEN construction and evaluation methods for human cell and animal applications Genes to Cells, 18, 4, 315-326 Genes to cells : devoted to molecular & cellular mechanisms, 18, 4, 315-326 Genes to Cells, 18, 4, 315-326 2013/04 Refereed English Disclose to all
K. Hayakawa; M. Ikeya; M. Fukuta; K. Woltjen; S. Tamaki; N. Takahara; T. Kato; S. Sato; T. Otsuka; J. Toguchida Hayakawa K, Ikeya M, Fukuta M, Woltjen K, Tamaki S, Takahara N, Kato T Jr, Sato S, Otsuka T, Toguchida J K. Hayakawa; M. Ikeya; M. Fukuta; K. Woltjen; S. Tamaki; N. Takahara; T. Kato; S. Sato; T. Otsuka; J. Toguchida Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells. Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells Biochemical and Biophysical Research Communications, 432, 4, 713-719 Biochemical and biophysical research communications, 432, 4, 713-719 Biochemical and Biophysical Research Communications, 432, 4, 713-719 2013/03 Refereed English Disclose to all
A. Yamashita; S. Liu; K. Woltjen; B. Thomas; G. Meng; A. Hotta; K. Takahashi; J. Ellis; S. Yamanaka; D.E. Rancourt Yamashita A, Liu S, Woltjen K, Thomas B, Meng G, Hotta A, Takahashi K, Ellis J, Yamanaka S, Rancourt DE A. Yamashita; S. Liu; K. Woltjen; B. Thomas; G. Meng; A. Hotta; K. Takahashi; J. Ellis; S. Yamanaka; D.E. Rancourt Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells. Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells Scientific Reports, 3, 1978 Scientific reports, 3, 1978 Scientific Reports, 3, 1978 2013 Refereed English Disclose to all
A. Tanaka; K. Woltjen; K. Miyake; A. Hotta; M. Ikeya; T. Yamamoto; T. Nishino; E. Shoji; A. Sehara-Fujisawa; Y. Manabe; N. Fujii; K. Hanaoka; T. Era; S. Yamashita; K.-I. Isobe; E. Kimura; H. Sakurai Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe K, Kimura E, Sakurai H A. Tanaka; K. Woltjen; K. Miyake; A. Hotta; M. Ikeya; T. Yamamoto; T. Nishino; E. Shoji; A. Sehara-Fujisawa; Y. Manabe; N. Fujii; K. Hanaoka; T. Era; S. Yamashita; K.-I. Isobe; E. Kimura; H. Sakurai Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro. Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro PLoS ONE, 8, 4, e61540 PloS one, 8, 4, e61540 PLoS ONE, 8, 4, e61540 2013 Refereed English Disclose to all
I.P. Michael; C. Monetti; A.C. Chiu; P. Zhang; T. Baba; K. Nishino; S. Agha-Mohammadi; K. Woltjen; H.-K. Sung; A. Nagy Michael IP, Monetti C, Chiu AC, Zhang P, Baba T, Nishino K, Agha-Mohammadi S, Woltjen K, Sung HK, Nagy A I.P. Michael; C. Monetti; A.C. Chiu; P. Zhang; T. Baba; K. Nishino; S. Agha-Mohammadi; K. Woltjen; H.-K. Sung; A. Nagy Highly efficient site-specific transgenesis in cancer cell lines Highly efficient site-specific transgenesis in cancer cell lines. Highly efficient site-specific transgenesis in cancer cell lines Molecular Cancer, 11, 89 Molecular cancer, 11, 89 Molecular Cancer, 11, 89 2012/12 Refereed English Disclose to all
M. Gabut; P. Samavarchi-Tehrani; X. Wang; V. Slobodeniuc; D. O'Hanlon; H.-K. Sung; M. Alvarez; S. Talukder; Q. Pan; E.O. Mazzoni; S. Nedelec; H. Wichterle; K. Woltjen; T.R. Hughes; P.W. Zandstra; A. Nagy; J.L. Wrana; B.J. Blencowe Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, Nagy A, Wrana JL, Blencowe BJ M. Gabut; P. Samavarchi-Tehrani; X. Wang; V. Slobodeniuc; D. O'Hanlon; H.-K. Sung; M. Alvarez; S. Talukder; Q. Pan; E.O. Mazzoni; S. Nedelec; H. Wichterle; K. Woltjen; T.R. Hughes; P.W. Zandstra; A. Nagy; J.L. Wrana; B.J. Blencowe An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming Cell, 147, 1, 132-146 Cell, 147, 1, 132-146 Cell, 147, 1, 132-146 2011/09 Refereed English Disclose to all
K. Nagy; H.-K. Sung; P. Zhang; S. Laflamme; P. Vincent; S. Agha-Mohammadi; K. Woltjen; C. Monetti; I.P. Michael; L.C. Smith; A. Nagy Nagy K, Sung HK, Zhang P, Laflamme S, Vincent P, Agha-Mohammadi S, Woltjen K, Monetti C, Michael IP, Smith LC, Nagy A K. Nagy; H.-K. Sung; P. Zhang; S. Laflamme; P. Vincent; S. Agha-Mohammadi; K. Woltjen; C. Monetti; I.P. Michael; L.C. Smith; A. Nagy Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts Induced pluripotent stem cell lines derived from equine fibroblasts. Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts Stem Cell Reviews and Reports, 7, 3, 693-702 Stem cell reviews, 7, 3, 693-702 Stem Cell Reviews and Reports, 7, 3, 693-702 2011/09 Refereed English Disclose to all
C. Monetti; K. Nishino; S. Biechele; P. Zhang; T. Baba; K. Woltjen; A. Nagy Monetti C, Nishino K, Biechele S, Zhang P, Baba T, Woltjen K, Nagy A C. Monetti; K. Nishino; S. Biechele; P. Zhang; T. Baba; K. Woltjen; A. Nagy PhiC31 integrase facilitates genetic approaches combining multiple recombinases PhiC31 integrase facilitates genetic approaches combining multiple recombinases. PhiC31 integrase facilitates genetic approaches combining multiple recombinases Methods, 53, 4, 380-385 Methods (San Diego, Calif.), 53, 4, 380-385 Methods, 53, 4, 380-385 2011/04 Refereed English Disclose to all
K. Woltjen; R. Hämäläinen; M. Kibschull; M. Mileikovsky; A. Nagy Woltjen K, Hämäläinen R, Kibschull M, Mileikovsky M, Nagy A K. Woltjen; R. Hämäläinen; M. Kibschull; M. Mileikovsky; A. Nagy Transgene-free production of pluripotent stem cells using piggyBac transposons Transgene-free production of pluripotent stem cells using piggyBac transposons. Transgene-free production of pluripotent stem cells using piggyBac transposons Methods in Molecular Biology, 767, 87-103 Methods in molecular biology (Clifton, N.J.), 767, 87-103 Methods in Molecular Biology, 767, 87-103 2011 Refereed English Disclose to all
P. Samavarchi-Tehrani; A. Golipour; L. David; H.-K. Sung; T.A. Beyer; A. Datti; K. Woltjen; A. Nagy; J.L. Wrana Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL P. Samavarchi-Tehrani; A. Golipour; L. David; H.-K. Sung; T.A. Beyer; A. Datti; K. Woltjen; A. Nagy; J.L. Wrana Functional genomics reveals a BMP-Driven mesenchymal-to-Epithelial transition in the initiation of somatic cell reprogramming Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Functional genomics reveals a BMP-Driven mesenchymal-to-Epithelial transition in the initiation of somatic cell reprogramming Cell Stem Cell, 7, 1, 64-77 Cell stem cell, 7, 1, 64-77 Cell Stem Cell, 7, 1, 64-77 2010/07 Refereed English Disclose to all
K. Woltjen; W.L. Stanford Woltjen K, Stanford WL K. Woltjen; W.L. Stanford Inhibition of Tgf-β Signaling Improves Mouse Fibroblast Reprogramming Preview. Inhibition of Tgf-beta signaling improves mouse fibroblast reprogramming. Inhibition of Tgf-β Signaling Improves Mouse Fibroblast Reprogramming Cell Stem Cell, 5, 5, 457-458 Cell stem cell, 5, 5, 457-458 Cell Stem Cell, 5, 5, 457-458 2009/11 Refereed English Disclose to all
J. O'Malley; K. Woltjen; K. Kaji O'Malley J, Woltjen K, Kaji K J. O'Malley; K. Woltjen; K. Kaji New strategies to generate induced pluripotent stem cells New strategies to generate induced pluripotent stem cells. New strategies to generate induced pluripotent stem cells Current Opinion in Biotechnology, 20, 5, 516-521 Current opinion in biotechnology, 20, 5, 516-521 Current Opinion in Biotechnology, 20, 5, 516-521 2009/10 Refereed English Disclose to all
K. Woltjen; I.P. Michael; P. Mohseni; R. Desai; M. Mileikovsky; R. Hämäläinen; R. Cowling; W. Wang; P. Liu; M. Gertsenstein; K. Kaji; H.-K. Sung; A. Nagy Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P, Gertsenstein M, Kaji K, Sung HK, Nagy A K. Woltjen; I.P. Michael; P. Mohseni; R. Desai; M. Mileikovsky; R. Hämäläinen; R. Cowling; W. Wang; P. Liu; M. Gertsenstein; K. Kaji; H.-K. Sung; A. Nagy PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells Nature, 458, 7239, 766-770 Nature, 458, 7239, 766-770 Nature, 458, 7239, 766-770 2009/04 Refereed English Disclose to all
K. Kaji; K. Norrby; A. Paca; M. Mileikovsky; P. Mohseni; K. Woltjen Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K K. Kaji; K. Norrby; A. Paca; M. Mileikovsky; P. Mohseni; K. Woltjen Virus-free induction of pluripotency and subsequent excision of reprogramming factors Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Virus-free induction of pluripotency and subsequent excision of reprogramming factors Nature, 458, 7239, 771-775 Nature, 458, 7239, 771-775 Nature, 458, 7239, 771-775 2009/04 Refereed English Disclose to all
Woltjen K, Ito K, Tsuzuki T, Rancourt DE Woltjen K, Ito K, Tsuzuki T, Rancourt DE Woltjen K, Ito K, Tsuzuki T, Rancourt DE Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement. Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement. Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement. Methods in molecular biology (Clifton, N.J.), 435, 79-94 Methods in molecular biology (Clifton, N.J.), 435, 79-94 Methods in molecular biology (Clifton, N.J.), 435, 79-94 2008 Refereed Disclose to all
B. Thomas; K. Woltjen; D.E. Rancourt Thomas B, Woltjen K, Rancourt DE B. Thomas; K. Woltjen; D.E. Rancourt Deep screening of recombination proficient bacteriophage libraries Deep screening of recombination proficient bacteriophage libraries. Deep screening of recombination proficient bacteriophage libraries BioTechniques, 34, 1, 36-8, 40 BioTechniques, 34, 1, 36-8, 40 BioTechniques, 34, 1, 36-8, 40 2003/01 Refereed English Disclose to all
K. Woltjen; M.W. Unger; D.E. Rancourt Woltjen K, Unger MW, Rancourt DE K. Woltjen; M.W. Unger; D.E. Rancourt Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Methods in molecular biology (Clifton, N.J.), 182, 189-207 Methods in molecular biology (Clifton, N.J.), 182, 189-207 Methods in molecular biology (Clifton, N.J.), 182, 189-207 2002 Refereed English Research paper(scientific journal) Disclose to all
K. Nagy; H.-K. Sung; P. Zhang; S. Laflamme; P. Vincent; S. Agha-Mohammadi; K. Woltjen; C. Monetti; I.P. Michael; L.C. Smith; A. Nagy K. Nagy; H.-K. Sung; P. Zhang; S. Laflamme; P. Vincent; S. Agha-Mohammadi; K. Woltjen; C. Monetti; I.P. Michael; L.C. Smith; A. Nagy Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (Stem Cell Rev and Rep, 10.1007/s12015-011-9239-5) Erratum to: Induced Pluripotent Stem Cell Lines Derived from Equine Fibroblasts (Stem Cell Rev and Rep, 10.1007/s12015-011-9239-5) Stem Cell Reviews and Reports, 8, 2, 546- , 8, 2, 546- Stem Cell Reviews and Reports, 8, 2, 546- 2012 Refereed English Disclose to all
Woltjen K, Hamalainen R, Kibschull M, Mileikovsky M, Nagy A. Woltjen K, Hamalainen R, Kibschull M, Mileikovsky M, Nagy A. Transposon-based production of genetically unmodified induced pluripotent stem cells from human embryonic fibroblasts Transposon-based production of genetically unmodified induced pluripotent stem cells from human embryonic fibroblasts Methods in Molecular Biology 767 (87):103 Methods in Molecular Biology 767 (87):103 2011 Refereed English Disclose to all
K. Sciabica; K. Woltjen; A. Hotta K. Sciabica; K. Woltjen; A. Hotta Obtaining Pluripotency Biomarker Signatures Obtaining Pluripotency Biomarker Signatures Genetic Engineering and Biotechnology News, 30, 3 , 30, 3 Genetic Engineering and Biotechnology News, 30, 3 2010 English Disclose to all
C. Aoyama; K. Woltjen; F.C. Mansergh; K. Ishidate; D.E. Rancourt C. Aoyama; K. Woltjen; F.C. Mansergh; K. Ishidate; D.E. Rancourt Bacteriophage gene targeting vectors generated by transplacement Bacteriophage gene targeting vectors generated by transplacement BioTechniques, 33, 4, 806-812 , 33, 4, 806-812 BioTechniques, 33, 4, 806-812 2002 Refereed English Disclose to all
K. Woltjen; G. Bain; D.E. Rancourt K. Woltjen; G. Bain; D.E. Rancourt Retro-recombination screening of a mouse embryonic stem cell genomic library. Retro-recombination screening of a mouse embryonic stem cell genomic library. Nucleic acids research, 28, 9, E41 , 28, 9, E41 Nucleic acids research, 28, 9, E41 2000 Refereed English Disclose to all

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Misc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
早川和男,福田誠,玉置さくら,佐藤信吾,池谷真,大塚隆信,Knut Woltjen,戸口田淳也 早川和男,福田誠,玉置さくら,佐藤信吾,池谷真,大塚隆信,Knut Woltjen,戸口田淳也 薬剤誘導型発現ベクターを用いたSYT-SSX 融合遺伝子導入iPS 細胞の樹立 薬剤誘導型発現ベクターを用いたSYT-SSX 融合遺伝子導入iPS 細胞の樹立 第45 回日本整形外科学会骨軟部腫瘍学術 集会(2012.7.15.東京) 第45 回日本整形外科学会骨軟部腫瘍学術 集会(2012.7.15.東京) 2012 Refereed Japanese Disclose to all
福田誠,早川和男,玉置さくら,沖田圭介,池谷真,Knut Woltjen,大塚隆信,戸口田淳也 福田誠,早川和男,玉置さくら,沖田圭介,池谷真,Knut Woltjen,大塚隆信,戸口田淳也 PS 細胞を用いた肉腫研究:滑膜肉腫の起源細胞の解明をめざして PS 細胞を用いた肉腫研究:滑膜肉腫の起源細胞の解明をめざして 第27 回日本整形外科学会基礎学術集会(2012.10.26. 名古屋) 第27 回日本整形外科学会基礎学術集会(2012.10.26. 名古屋) 2012 Refereed Japanese Disclose to all
Hayakawa K, Fukuta M, TamaiS, Kato T, Ikeya M, Otsuka T, Woltjen K, Toguchida J. Hayakawa K, Fukuta M, TamaiS, Kato T, Ikeya M, Otsuka T, Woltjen K, Toguchida J. Application of iPS cell technology \nfor the analysis of origin-unknown sarcoma characterized by a specific fusion gene. Application of iPS cell technology \nfor the analysis of origin-unknown sarcoma characterized by a specific fusion gene. 第17 回CTOS (2012.11.16.Prague) 第17 回CTOS (2012.11.16.Prague) 2012/11/16 Refereed English Disclose to all
Fukuta M, Hayakawa K, Tamaki S, Sato S, Ikeya M, Otsuka Y, Woltjen K, Toguchida J. Fukuta M, Hayakawa K, Tamaki S, Sato S, Ikeya M, Otsuka Y, Woltjen K, Toguchida J. Establishment and functional \nanalysis of iPS cells with drug-inducible SYT-SSX fusion gene. Establishment and functional \nanalysis of iPS cells with drug-inducible SYT-SSX fusion gene. 第10 回ISSCR(2012.6.14.横浜) 第10 回ISSCR(2012.6.14.横浜) 2012 Refereed English Disclose to all
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Conference Activities & Talks
Title Title(Japanese) Title(English) Conference Conference(Japanese) Conference(English) Promotor Promotor(Japanese) Promotor(English) Date Language Assortment Disclose
Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining[Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019 Keystone Symposia 『Genome Engineering: From Mechanisms to Therapies (B4)』 2019/02/21 English Oral presentation(invited, special) Disclose to all
The history and potential of iPSC research[Invited] The history and potential of iPSC research [Invited] The history and potential of iPSC research [Invited] AAAS 2019 Annual Meeting AAAS 2019 Annual Meeting AAAS 2019 Annual Meeting 2019/02/15 English Oral presentation(invited, special) Disclose to all
医療応用に向けたヒトiPS細胞でのゲノム編集[Invited] 医療応用に向けたヒトiPS細胞でのゲノム編集 [Invited] OPERA「ゲノム編集」産学共創コンソーシアム・公開シンポジウム、卓越大学院キックオフシンポジウム OPERA「ゲノム編集」産学共創コンソーシアム・公開シンポジウム、卓越大学院キックオフシンポジウム 2018/12/10 English Symposium workshop panel(nominated) Disclose to all
Japan’s experience in regenerative medicine and superdonor cells[Invited] Japan’s experience in regenerative medicine and superdonor cells [Invited] Japan’s experience in regenerative medicine and superdonor cells [Invited] NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ NRC’s HEALTH CHALLENGE PROGRAM WORKSHOP : ‘Transforming Health Outcomes through Engineered Cell and Gene Therapies’ 2018/12/07 English Symposium workshop panel(nominated) Disclose to all
Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining[Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Precise Human Disease Allele Creation and Correction through Microhomology-Mediated End Joining [Invited] Concordia University Seminar Concordia University Seminar Concordia University Seminar 2018/12/06 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] The 41st Annual Meeting of the Molecular Biology Society of Japan 第41回日本分子生物学会年会 The 41st Annual Meeting of the Molecular Biology Society of Japan 2018/11/28 English Oral presentation(invited, special) Disclose to all
Genome editing in stem cells to study the mechanisms of reprogramming and human disease[Invited] Genome editing in stem cells to study the mechanisms of reprogramming and human disease [Invited] Genome editing in stem cells to study the mechanisms of reprogramming and human disease [Invited] Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) Basel Stem Cell Network (BSCN) International Lecture Series(@ETH Zürich, D-BSSE) 2018/09/14 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining Creation and correction of human disease alleles in iPSCs through microhomology-mediated end joining EMBO at BASEL LIFE 2018 EMBO at BASEL LIFE 2018 EMBO at BASEL LIFE 2018 2018/09/13 English Oral presentation(invited, special) Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] IREM seminar( University of Zurich) IREM seminar( University of Zurich) IREM seminar( University of Zurich) 2018/09/12 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Precise human disease allele creation and correction through microhomology-mediated end joining[Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Precise human disease allele creation and correction through microhomology-mediated end joining [Invited] Genome Engineering: The CRISPR-Cas Revolution Genome Engineering: The CRISPR-Cas Revolution Genome Engineering: The CRISPR-Cas Revolution 2018/08/25 English Oral presentation(invited, special) Disclose to all
Employing microhomology-mediated end joining for the creation and correction of human disease alleles[Invited] Employing microhomology-mediated end joining for the creation and correction of human disease alleles [Invited] Employing microhomology-mediated end joining for the creation and correction of human disease alleles [Invited] Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) Developmental Biology Guest Research Seminar(Memorial Sloan Kettering Cancer Center) 2018/08/22 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ)[Invited] Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] Scarless editing of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] 3rd Annual Meeting of The Japanese Society for Genome Editing 日本ゲノム編集学会第3回大会 3rd Annual Meeting of The Japanese Society for Genome Editing 2018/06/19 English Oral presentation(invited, special) Disclose to all
GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA[Invited] GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA [Invited] GENES AND CELLS: THE LIVING DRUGS OF A NEW MEDICAL ERA [Invited] "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) 2018/03/29 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
The development of induced pluripotent stem cells and emerging tools for genome editing[Invited] The development of induced pluripotent stem cells and emerging tools for genome editing [Invited] The development of induced pluripotent stem cells and emerging tools for genome editing [Invited] "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) "Stem Cells and Regenerative Medicine: What does the Future Hold?" (The University of British Columbia ) 2018/03/28 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ)[Invited] Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] Creation and correction of human disease alleles through microhomology-mediated end joining (MMEJ) [Invited] The 9th Takeda Science Foundation Symposium on PharmaSciences 第9回武田科学振興財団薬科学シンポジウム The 9th Takeda Science Foundation Symposium on PharmaSciences 2018/02/07 English Symposium workshop panel(nominated) Disclose to all
Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells[Invited] Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells [Invited] Endogenous DNA repair pathways for gene editing in human induced pluripotent stem cells [Invited] Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) Celllular & Physiological Sciences Departmental Seminar(The University of British Columbia ) 2017/09/14 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Genetic engineering of iPS cells for modelling genodermatoses[Invited] Genetic engineering of iPS cells for modelling genodermatoses [Invited] Genetic engineering of iPS cells for modelling genodermatoses [Invited] The 38th Annual Meeting of the Japanese Society of Inflammation and Regeneration 第38回日本炎症・再生医学会 The 38th Annual Meeting of the Japanese Society of Inflammation and Regeneration 2017/07/19 English Oral presentation(invited, special) Disclose to all
Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs[Invited] Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs [Invited] Simultaneous derivation of point-mutants and concordant isogenic clones from human iPSCs [Invited] 2nd Annual Meeting of The Japanese Society for Genome Editing 日本ゲノム編集学会第2回大会 2nd Annual Meeting of The Japanese Society for Genome Editing 2017/06/29 English Oral presentation(invited, special) Disclose to all
Genetic engineering of pluripotent stem cells by CRISPR/Cas[Invited] Genetic engineering of pluripotent stem cells by CRISPR/Cas [Invited] Genetic engineering of pluripotent stem cells by CRISPR/Cas [Invited] 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 糖尿病ミニシンポジウム「Kyoto Diabetes Mini-Symposium – Beta-Cell Replacement Strategies」 2017/06/05 English Symposium workshop panel(nominated) Disclose to all
Engineering iPS cell models of human disease[Invited] Engineering iPS cell models of human disease [Invited] Engineering iPS cell models of human disease [Invited] The 75th Annual Meeting of the Japanese Cancer Association 第75回日本癌学会学術総会 The 75th Annual Meeting of the Japanese Cancer Association 2016/10/07 English Oral presentation(invited, special) Disclose to all
An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming[Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] Liaison Laboratory Regular Seminar/HIGO Program Cutting-edge Seminar 熊本大学リエゾンラボ研究会/HIGOプログラム最先端研究セミナー Liaison Laboratory Regular Seminar/HIGO Program Cutting-edge Seminar 2016/02/17 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming[Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming [Invited] 九州大学大学院医学研究院 第35回生命医科学セミナー 九州大学大学院医学研究院 第35回生命医科学セミナー 2016/02/16 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology[Invited] At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology [Invited] At the Conflux of Genome Engineering and Pluripotent Stem Cell Biology [Invited] Conference on Transposition and Genome Engineering 2015 Conference on Transposition and Genome Engineering 2015 Conference on Transposition and Genome Engineering 2015 2015/11/20 English Oral presentation(invited, special) Disclose to all
Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling[Invited] Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling [Invited] Engineering the Human Genome: Strategies for iPS Cell Derivation and Disease Modeling [Invited] Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) Wakate International Symposium “Discovery of Medical Sciences,” (WISDoMS) 2014/11/06 English Oral presentation(invited, special) Disclose to all
From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling[Invited] From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling [Invited] From Transposons to Nucleases: Genome Engineering Strategies for iPS Cell Derivation and Disease Modeling [Invited] The 71st of Stem Cell Biology and Regenerative Medicine Forum The 71th of Stem Cell Biology and Regenerative Medicine Forum The 71st of Stem Cell Biology and Regenerative Medicine Forum 2014/06/30 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Recombinant DNA and Cell Technologies Enabling Human Functional Genomics[Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Tokyo Tech Bio 2013 Tokyo Tech Bio 2013 Tokyo Tech Bio 2013 2014/01/29 English Symposium workshop panel(nominated) Disclose to all
Recombinant DNA and Cell Technologies Enabling Human Functional Genomics[Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Recombinant DNA and Cell Technologies Enabling Human Functional Genomics [Invited] Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) Department of Biological Sciences Molecules, Cells, and Systems Seminar Series (University of Alberta) 2013/11/04 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation[Invited] Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation [Invited] Transposed and targeted expression systems for guiding somatic cell reprogramming and differentiation [Invited] Transposition and Genome Engineering 2013 Transposition and Genome Engineering 2013 Transposition and Genome Engineering 2013 2013/09 English Oral presentation(invited, special) Disclose to all
Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation[Invited] Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation [Invited] Transposed and Targeted Gene Expression Systems for Guiding Somatic Cell Reprogramming and Differentiation [Invited] 46th Annual Meeting of the Japanese Society of Development Biologists 第46回日本発生生物学会 46th Annual Meeting of the Japanese Society of Development Biologists 2013/05/31 English Oral presentation(invited, special) Disclose to all
Cell Identity Transitions During Induced Reprogramming to Pluripotency[Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] The 7th Annual Meeting of the Japanese Society for Epigenetics 第7回日本エピジェネティクス研究会年会 The 7th Annual Meeting of the Japanese Society for Epigenetics 2013/05 English Oral presentation(invited, special) Disclose to all
Cell Identity Transitions During Induced Reprogramming to Pluripotency[Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] Cell Identity Transitions During Induced Reprogramming to Pluripotency [Invited] CDB Seminar CDB Seminar CDB Seminar 2013/03/29 English Public discourse, seminar, tutorial, course, lecture and others Disclose to all
Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation[Invited] Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation [Invited] Transposon Systems to Guiding Somatic Cell Reprogramming and Differentiation [Invited] iCeMS-Stem Cells Australia Joint Symposium iCeMS-Stem Cells Australia Joint Symposium iCeMS-Stem Cells Australia Joint Symposium 2013/02/12 English Symposium workshop panel(nominated) Disclose to all

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Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
Harunobu Kagawa, Tomoko Matsumoto, Shin-Il Kim, and Knut Woltjen 香川 晴信、松本 智子、金 信一、ウォルツェン クヌート Harunobu Kagawa, Tomoko Matsumoto, Shin-Il Kim, and Knut Woltjen iPS細胞を用いた正確な ゲノム編集法(MhAX法) iPS細胞を用いた正確な ゲノム編集法(MhAX法) iPS細胞を用いた正確な ゲノム編集法(MhAX法) 実験医学 実験医学 実験医学 2018/10 Contributor Disclose to all
Title language:
Patents
Inventor(s) Inventor(s) (Japanese) Inventor(s) (English) Title Title(Japanese) Title(English) Stage Patent number Date Disclose
ウォルツェン クヌート、金 信一、松本 智子 ウォルツェン クヌート、金 信一、松本 智子 Knut Woltjen, Shin-Il Kim, Tomoko Matsumoto Method for genome editing Method for genome editing Method for genome editing 特許出願 特願PCT/IB2017/054736 2017/08/02 Disclose to all
Title language:
External funds: competitive funds and Grants-in-Aid for Scientific Research (Kakenhi)
Type Position Title(Japanese) Title(English) Period
若手研究(B) Representative トランスポゾンを利用した一塩基レベル遺伝子ターゲティング 2011-2013
External funds: other than those above
System Main person Title(Japanese) Title(English) Period
リプログラミング開始における細胞応答の解析 Immediate Early Events in Reprogramming Leading to Cellular Plasticity 2010-2012
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2013/04-2014/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2014/04-2015/03
Global Frontier in Life Science A Global Frontier in Life Science A 前期 生命科学研究科 2015/04-2016/03