植田 和光

Last Update: 2018/07/17 13:59:23

Print

Name(Kanji/Kana/Abecedarium Latinum)
植田 和光/ウエダ カズミツ/Kazumitsu Ueda
Primary department(Org1/Job title)
Graduate Schools Agriculture/Professor
Faculty
Org1 Job title
農学部
Secondary departments to which you belong
Org1 Job title
Graduate Schools Agriculture 協力教員(教授)
Contact address
Type Address(Japanese) Address(English)
Office 606-8502 京都府京都市左京区北白川 Laboratory of Cellular Biochemistry,Division of Applied Life Sciences,Graduate School of Agriculture, Kyoto University,Kitasirakawa, Sakyo-ku,Kyoto 606-8502, Japan
Phone
Type Number
Office 075-753-6124
Affiliated academic organization(s) (Japanese)
Organization name(Japanese) Organization name(English)
日本農芸化学会
日本生化学会
日本分子生物学会
Academic degree
Field(Japanese) Field(English) University(Japanese) University(English) Method
農学修士 京都大学
農学博士 京都大学
Graduate school
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(Japanese) Major(English) Degree
京都大学 大学院農学研究科修士課程 修了
University
University(Japanese) University(English) Faculty(Japanese) Faculty(English) Major(s)(Japanese) Major(s)(English) Degree
京都大学 農学部農芸化学科 卒業
Work Experience
Period Organization(Japanese) Organization(English) Job title(Japanese) Job title(English)
-
ORCID ID
orcid.org/0000-0003-2980-6078
Research Topics
(Japanese)
ABC蛋白質の分子メカニズムの解明 HDL産生機構の解明
(English)
Molecular mechanism of ABC proteins Mechanism of HDL formation
Overview of your research
(Japanese)
私たちの身体は、約60兆個の細胞でできています。それらのうち、数千億個の細胞が毎日死に、新しい細胞に置き換わっています。つまり、私たちの身体の細胞は、半年もするとほぼすべて新しい細胞に置き換わるのです。それらの新しい細胞は、私たちが毎日食べている食物中の肉や穀物に含まれているアミノ酸、糖類や脂質をもとにして作られます。肉や穀物は消化されたのち、アミノ酸、糖、脂質として小腸から吸収され、肝臓に運ばれた後、全身の細胞へと血流に乗って運ばれ私たちの身体となります。私たちが健康を保つためには、吸収された栄養素が全身の細胞へと運ばれる仕組みがきちんと働く必要があります。 脂質のひとつであるコレステロールは、一般に悪者のように言われますが、実は細胞を作る上で非常に重要な栄養素のひとつです。しかし、コレステロールが過剰にたまると細胞が死んでしまうため、悪者のように言われています。コレステロールを過剰にため込んだ細胞が動脈壁に沈着し血液が流れにくくなる動脈硬化は、先進国の死因の約4分の1を占めるのです。 全身の細胞で過剰になったコレステロールは、善玉コレステロールと呼ばれるHDL粒子として血流を介して肝臓へ戻されます。一方、悪玉コレステロールLDLは、肝臓から全身の細胞へコレステロールを届けるためにあります。どちらも体にとっては必要なものですが、LDLが多いと動脈硬化になりやすいため、悪玉と呼ばれます。 私たちは、HDLが産生されるメカニズムを研究しています。私たちは、脂溶性物質が体の中で運ばれる仕組みを30年前に世界で初めて明らかにしました。それ以来、脂溶性物質やコレステロールが運ばれる仕組みを研究しています。HDLが多い人は動脈硬化になりにくいことがわかっています。私たちの研究でHDLの産生機構が明らかになれば、動脈硬化を予防できると期待されます。
(English)
Our body is made of 60 trillion cells and hundreds of billions of the cells die and are renewed with fresh ones every day. The fresh cells are constructed by using amino acids, carbohydrates and lipids contained in daily diet. Meat, grains and other food are digested, and the nutrients are absorbed from intestine. They are first delivered to liver and then transported to all the body cells to be used as materials for the cells. To maintain our life and health, absorbed nutrients should be transported properly via bloodstream to all the body cells. Cholesterol, one of lipids, is also a very important nutrient to construct cells. However, it has a bad reputation, because its over-accumulation destroys cells. Buildup of dead cells, in which cholesterol is over-accumulated, in artery wall hampers blood flow and causes atherosclerosis. Cholesterol is delivered from liver to all the body cells through bloodstream as LDL particles, so-called bad cholesterol, and excess cholesterol in body cells are reversely transported to liver through bloodstream as HDL particles, so-called good cholesterol. While both LDL and HDL particles are necessary for us, people with high LDL in blood have high risk of atherosclerosis. It is why LDL particles are called bad cholesterol. 30 years ago, we discovered the mechanism by which lipophilic compounds are transported in our body for the first time. When our body has some defects in transporting lipophilic compounds including cholesterol, we suffer from various diseases, such as atherosclerosis, Alzheimer’s disease, skin diseases, eye diseases. Ueda group is trying to reveal the mechanism of lipid transport and HDL generation and to find ways to prevent and cure various diseases which trouble us.
Fields of research (key words)
Key words(Japanese) Key words(English)
農芸化学,脂質生化学, 分子細胞生物学 Lipid biochemistry, Molecular Cell Biology, Agricultural Chemistry
Fields of research (kaken code)
Kaken code
Applied Biochemistry
Cell biology
Fundamental informatics
Published Papers
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Bibliography Bibliography(Japanese) Bibliography(English) Publication date Refereed paper Language Publishing type Disclose
Ishigami M, Ogasawara F, Nagao K, Hashimoto H, Kimura Y, Kioka N, Ueda K Ishigami M, Ogasawara F, Nagao K, Hashimoto H, Kimura Y, Kioka N, Ueda K Ishigami M, Ogasawara F, Nagao K, Hashimoto H, Kimura Y, Kioka N, Ueda K Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation. Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation. Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation. Scientific reports,8,1,6170 Scientific reports,8,1,6170 Scientific reports,8,1,6170 2018/04 Refereed Disclose to all
Perea A, Manzano JI, Kimura Y, Ueda K, Castanys S, Gamarro F Perea A, Manzano JI, Kimura Y, Ueda K, Castanys S, Gamarro F Perea A, Manzano JI, Kimura Y, Ueda K, Castanys S, Gamarro F <i>Leishmania</i> LABCG2 transporter is involved in ATP-dependent transport of thiols. <i>Leishmania</i> LABCG2 transporter is involved in ATP-dependent transport of thiols. <i>Leishmania</i> LABCG2 transporter is involved in ATP-dependent transport of thiols. The Biochemical journal,475,1,87-97 The Biochemical journal,475,1,87-97 The Biochemical journal,475,1,87-97 2018/01 Refereed Disclose to all
Ichikawa T, Kita M, Matsui TS, Nagasato AI, Araki T, Chiang SH, Sezaki T, Kimura Y, Ueda K, Deguchi S, Saltiel AR, Kioka N Ichikawa T, Kita M, Matsui TS, Nagasato AI, Araki T, Chiang SH, Sezaki T, Kimura Y, Ueda K, Deguchi S, Saltiel AR, Kioka N Ichikawa T, Kita M, Matsui TS, Nagasato AI, Araki T, Chiang SH, Sezaki T, Kimura Y, Ueda K, Deguchi S, Saltiel AR, Kioka N Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. Journal of cell science,130,20,3517-3531 Journal of cell science,130,20,3517-3531 Journal of cell science,130,20,3517-3531 2017/10 Refereed Disclose to all
Tomioka M, Toda Y, Mañucat NB, Akatsu H, Fukumoto M, Kono N, Arai H, Kioka N, Ueda K, Biochimica et biophysica acta, vol. 1862, no. 7, pp. 658-665 Tomioka M, Toda Y, Mañucat NB, Akatsu H, Fukumoto M, Kono N, Arai H, Kioka N, Ueda K, Biochimica et biophysica acta, vol. 1862, no. 7, pp. 658-665 Tomioka M, Toda Y, Mañucat NB, Akatsu H, Fukumoto M, Kono N, Arai H, Kioka N, Ueda K, Biochimica et biophysica acta, vol. 1862, no. 7, pp. 658-665 Lysophosphatidylcholine export by human ABCA7. Lysophosphatidylcholine export by human ABCA7. Lysophosphatidylcholine export by human ABCA7. ,1862,7,658-665 ,1862,7,658-665 ,1862,7,658-665 2017/07 Refereed Disclose to all
Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N, Bioscience, biotechnology, biochemistry, vol. 81, no. 6, pp. 1136-1147 Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N, Bioscience, biotechnology, biochemistry, vol. 81, no. 6, pp. 1136-1147 Nagasato AI, Yamashita H, Matsuo M, Ueda K, Kioka N, Bioscience, biotechnology, biochemistry, vol. 81, no. 6, pp. 1136-1147 The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix. The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix. The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix. ,81,6,1136-1147 ,81,6,1136-1147 ,81,6,1136-1147 2017/06 Refereed Disclose to all
Liu SL, Sheng R, Jung JH, Wang L, Stec E, O'Connor MJ, Song S, Bikkavilli RK, Winn RA, Lee D, Baek K, Ueda K, Levitan I, Kim KP, Cho W, Nature chemical biology, vol. 13, no. 3, pp. 268-274 Liu SL, Sheng R, Jung JH, Wang L, Stec E, O'Connor MJ, Song S, Bikkavilli RK, Winn RA, Lee D, Baek K, Ueda K, Levitan I, Kim KP, Cho W, Nature chemical biology, vol. 13, no. 3, pp. 268-274 Liu SL, Sheng R, Jung JH, Wang L, Stec E, O'Connor MJ, Song S, Bikkavilli RK, Winn RA, Lee D, Baek K, Ueda K, Levitan I, Kim KP, Cho W, Nature chemical biology, vol. 13, no. 3, pp. 268-274 Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol. Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol. Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol. ,13,3,268-274 ,13,3,268-274 ,13,3,268-274 2017/03 Refereed Disclose to all
Kuroda M, Wada H, Kimura Y, Ueda K, Kioka N, Journal of cell science, vol. 130, no. 5, pp. 989-1002 Kuroda M, Wada H, Kimura Y, Ueda K, Kioka N, Journal of cell science, vol. 130, no. 5, pp. 989-1002 Kuroda M, Wada H, Kimura Y, Ueda K, Kioka N, Journal of cell science, vol. 130, no. 5, pp. 989-1002 Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes. Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes. Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes. ,130,5,989-1002 ,130,5,989-1002 ,130,5,989-1002 2017/03 Refereed Disclose to all
Mao D, Ando S, Sato SI, Qin Y, Hirata N, Katsuda Y, Kawase E, Kuo TF, Minami I, Shiba Y, Ueda K, Nakatsuji N, Uesugi M, Angewandte Chemie, International ed. in English), vol. 56, no. 7, pp. 1765-1770 Mao D, Ando S, Sato SI, Qin Y, Hirata N, Katsuda Y, Kawase E, Kuo TF, Minami I, Shiba Y, Ueda K, Nakatsuji N, Uesugi M, Angewandte Chemie, International ed. in English), vol. 56, no. 7, pp. 1765-1770 Mao D, Ando S, Sato SI, Qin Y, Hirata N, Katsuda Y, Kawase E, Kuo TF, Minami I, Shiba Y, Ueda K, Nakatsuji N, Uesugi M, Angewandte Chemie, International ed. in English), vol. 56, no. 7, pp. 1765-1770 A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures. A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures. A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures. ,56,7,1765-1770 ,56,7,1765-1770 ,56,7,1765-1770 2017/02 Refereed Disclose to all
Ueda K, Bioscience, biotechnology, biochemistry, vol. 81, no. 1, pp. 1-2 Ueda K, Bioscience, biotechnology, biochemistry, vol. 81, no. 1, pp. 1-2 Ueda K, Bioscience, biotechnology, biochemistry, vol. 81, no. 1, pp. 1-2 Celebrating Dr. Satoshi Ōmura, the recipient of the 2015 Nobel Prize in Physiology or Medicine. Celebrating Dr. Satoshi Ōmura, the recipient of the 2015 Nobel Prize in Physiology or Medicine. Celebrating Dr. Satoshi Ōmura, the recipient of the 2015 Nobel Prize in Physiology or Medicine. ,81,1,1-2 ,81,1,1-2 ,81,1,1-2 2017/01 Refereed Disclose to all
Omachi T, Ichikawa T, Kimura Y, Ueda K, Kioka N Omachi T, Ichikawa T, Kimura Y, Ueda K, Kioka N Omachi T, Ichikawa T, Kimura Y, Ueda K, Kioka N Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior. Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior. Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior. PloS one,12,4,e0175324 PloS one,12,4,e0175324 PloS one,12,4,e0175324 2017 Refereed Disclose to all
Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Bioorganic, medicinal chemistry, vol. 24, no. 14, pp. 3184-3191 Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Bioorganic, medicinal chemistry, vol. 24, no. 14, pp. 3184-3191 Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Bioorganic, medicinal chemistry, vol. 24, no. 14, pp. 3184-3191 Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. ,24,14,3184-3191 ,24,14,3184-3191 ,24,14,3184-3191 2016/07 Refereed Disclose to all
Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Toxicology, applied pharmacology, vol. 298, pp. 40-47 Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Toxicology, applied pharmacology, vol. 298, pp. 40-47 Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M, Toxicology, applied pharmacology, vol. 298, pp. 40-47 In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines. In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines. In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines. ,298,40-47 ,298,40-47 ,298,40-47 2016/05 Refereed Disclose to all
Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, Matsuo M, PloS one, vol. 11, no. 5, pp. e0155400 Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, Matsuo M, PloS one, vol. 11, no. 5, pp. e0155400 Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, Remaley AT, Michikawa M, Ueda K, Matsuo M, PloS one, vol. 11, no. 5, pp. e0155400 ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production. ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production. ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production. ,11,5,e0155400 ,11,5,e0155400 ,11,5,e0155400 2016 Refereed Disclose to all
Nakato M, Matsuo M, Kono N, Arita M, Arai H, Ogawa J, Kioka N, Ueda K Nakato M, Matsuo M, Kono N, Arita M, Arai H, Ogawa J, Kioka N, Ueda K Nakato M, Matsuo M, Kono N, Arita M, Arai H, Ogawa J, Kioka N, Ueda K Neurite outgrowth stimulation by n3 and n6 polyunsaturated fatty acids of phospholipids in apolipoprotein E containing lipoproteins secreted from glial cells. Neurite outgrowth stimulation by n3 and n6 polyunsaturated fatty acids of phospholipids in apolipoprotein E containing lipoproteins secreted from glial cells. Neurite outgrowth stimulation by n3 and n6 polyunsaturated fatty acids of phospholipids in apolipoprotein E containing lipoproteins secreted from glial cells. Journal of lipid research,56,10,1880-1890 Journal of lipid research,56,10,1880-1890 Journal of lipid research,56,10,1880-1890 2015/08 Refereed Disclose to all
Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S Deficiency in the lipid exporter ABCA1 impairs retrograde sterol movement and disrupts sterol sensing at the endoplasmic reticulum. Deficiency in the lipid exporter ABCA1 impairs retrograde sterol movement and disrupts sterol sensing at the endoplasmic reticulum. Deficiency in the lipid exporter ABCA1 impairs retrograde sterol movement and disrupts sterol sensing at the endoplasmic reticulum. The Journal of biological chemistry,290,39,23464-23477 The Journal of biological chemistry,290,39,23464-23477 The Journal of biological chemistry,290,39,23464-23477 2015/07 Refereed Disclose to all
Zhao Y, Ishigami M, Nagao K, Hanada K, Kono N, Arai H, Matsuo M, Kioka N, Ueda K Zhao Y, Ishigami M, Nagao K, Hanada K, Kono N, Arai H, Matsuo M, Kioka N, Ueda K Zhao Y, Ishigami M, Nagao K, Hanada K, Kono N, Arai H, Matsuo M, Kioka N, Ueda K ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner. ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner. ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner. Journal of lipid research,56,3,644-652 Journal of lipid research,56,3,644-652 Journal of lipid research,56,3,644-652 2015/03 Refereed Disclose to all
Itoh S, Nagao K, Kimura Y, Matsuo M, Kioka N, Ueda K Itoh S, Nagao K, Kimura Y, Matsuo M, Kioka N, Ueda K Itoh S, Nagao K, Kimura Y, Matsuo M, Kioka N, Ueda K Position 834 in TM6 plays an important role in cholesterol and phosphatidylcholine transport by ABCA1. Position 834 in TM6 plays an important role in cholesterol and phosphatidylcholine transport by ABCA1. Position 834 in TM6 plays an important role in cholesterol and phosphatidylcholine transport by ABCA1. Bioscience, biotechnology, and biochemistry,79,5,775-781 Bioscience, biotechnology, and biochemistry,79,5,775-781 Bioscience, biotechnology, and biochemistry,79,5,775-781 2015 Refereed Disclose to all
Omura R, Nagao K, Kobayashi N, Ueda K, Saito H Omura R, Nagao K, Kobayashi N, Ueda K, Saito H Omura R, Nagao K, Kobayashi N, Ueda K, Saito H Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I. Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I. Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I. Journal of lipid research,55,11,2423-2431 Journal of lipid research,55,11,2423-2431 Journal of lipid research,55,11,2423-2431 2014/11 Refereed Disclose to all
Kuo TF, Mao D, Hirata N, Khambu B, Kimura Y, Kawase E, Shimogawa H, Ojika M, Nakatsuji N, Ueda K, Uesugi M Kuo TF, Mao D, Hirata N, Khambu B, Kimura Y, Kawase E, Shimogawa H, Ojika M, Nakatsuji N, Ueda K, Uesugi M Kuo TF, Mao D, Hirata N, Khambu B, Kimura Y, Kawase E, Shimogawa H, Ojika M, Nakatsuji N, Ueda K, Uesugi M Selective elimination of human pluripotent stem cells by a marine natural product derivative. Selective elimination of human pluripotent stem cells by a marine natural product derivative. Selective elimination of human pluripotent stem cells by a marine natural product derivative. Journal of the American Chemical Society,136,28,9798-9801 Journal of the American Chemical Society,136,28,9798-9801 Journal of the American Chemical Society,136,28,9798-9801 2014/07 Refereed Disclose to all
N. Hirata; M. Nakagawa; Y. Fujibayashi; K. Yamauchi; A. Murata; I. Minami; M. Tomioka; T. Kondo; T.-F. Kuo; H. Endo; H. Inoue; S.-I. Sato; S. Ando; Y. Kawazoe; K. Aiba; K. Nagata; E. Kawase; Y.-T. Chang; H. Suemori; K. Eto; H. Nakauchi; S. Yamanaka; N. Nakatsuji; K. Ueda; M. Uesugi Hirata N, Nakagawa M, Fujibayashi Y, Yamauchi K, Murata A, Minami I, Tomioka M, Kondo T, Kuo TF, Endo H, Inoue H, Sato S, Ando S, Kawazoe Y, Aiba K, Nagata K, Kawase E, Chang YT, Suemori H, Eto K, Nakauchi H, Yamanaka S, Nakatsuji N, Ueda K, Uesugi M N. Hirata; M. Nakagawa; Y. Fujibayashi; K. Yamauchi; A. Murata; I. Minami; M. Tomioka; T. Kondo; T.-F. Kuo; H. Endo; H. Inoue; S.-I. Sato; S. Ando; Y. Kawazoe; K. Aiba; K. Nagata; E. Kawase; Y.-T. Chang; H. Suemori; K. Eto; H. Nakauchi; S. Yamanaka; N. Nakatsuji; K. Ueda; M. Uesugi A Chemical Probe that Labels Human Pluripotent Stem Cells A chemical probe that labels human pluripotent stem cells. A Chemical Probe that Labels Human Pluripotent Stem Cells Cell Reports,6,6,1165-1174 Cell reports,6,6,1165-1174 Cell Reports,6,6,1165-1174 2014/03 Refereed English Disclose to all
Chiba T, Sakurada T, Watanabe R, Yamaguchi K, Kimura Y, Kioka N, Kawagishi H, Matsuo M, Ueda K Chiba T, Sakurada T, Watanabe R, Yamaguchi K, Kimura Y, Kioka N, Kawagishi H, Matsuo M, Ueda K Chiba T, Sakurada T, Watanabe R, Yamaguchi K, Kimura Y, Kioka N, Kawagishi H, Matsuo M, Ueda K Fomiroid A, a novel compound from the mushroom fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. Fomiroid A, a novel compound from the mushroom fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. Fomiroid A, a novel compound from the mushroom fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. PloS one,9,12,e116162 PloS one,9,12,e116162 PloS one,9,12,e116162 2014 Refereed Disclose to all
Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, Matsuo M Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, Matsuo M Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, Matsuo M ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane. ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane. ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane. PloS one,9,10 PloS one,9,10 PloS one,9,10 2014 Refereed Disclose to all
K. Ueda; K. Takahashi; A. Kobayashi; M. Matsuo K. Ueda; K. Takahashi; A. Kobayashi; M. Matsuo ABC proteins move lipids ABC proteins move lipids Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.,51,4,342-349 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.,51,4,342-349 ,51,4,342-349 2006 Refereed Japanese Disclose to all
K. Ueda K. Ueda ABC proteins involved in lipid homeostasis ABC proteins involved in lipid homeostasis Seikagaku. The Journal of Japanese Biochemical Society,76,6,525-531 Seikagaku. The Journal of Japanese Biochemical Society,76,6,525-531 ,76,6,525-531 2004 Refereed Japanese Disclose to all
M. Matsuo; K. Ueda M. Matsuo; K. Ueda XYZ of ABC proteins?: where is the goal for the study of ABC protein structure? XYZ of ABC proteins?: where is the goal for the study of ABC protein structure? Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,47,11,1431-1438 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,47,11,1431-1438 ,47,11,1431-1438 2002 Refereed Japanese Disclose to all
植田和光 植田和光 Molecular mechanism of multidrug transporter MDR 1: ABC in host-defense machinery. Molecular mechanism of multidrug transporter MDR 1: ABC in host-defense machinery. 蛋白質 核酸 酵素,46,5,588-595 蛋白質 核酸 酵素,46,5,588-595 ,46,5,588-595 2001/04/01 Refereed Japanese Disclose to all
植田 和光 植田 和光 分子メカニズムと生体防御機構における役割 分子メカニズムと生体防御機構における役割 バイオサイエンスとインダストリー = Bioscience & industry,58,1,24-27 バイオサイエンスとインダストリー = Bioscience & industry,58,1,24-27 ,58,1,24-27 2000/01/01 Refereed Japanese Disclose to all
植田 和光 植田 和光 ABCトランスポーター:医薬開発のターゲット ABCトランスポーター:医薬開発のターゲット バイオサイエンスとインダストリー,58/,23 バイオサイエンスとインダストリー,58/,23 2000 Refereed Japanese Disclose to all
植田 和光 植田 和光 環境有害物質に対する生物防御の分子メカニズム 環境有害物質に対する生物防御の分子メカニズム 農化,74/,791-794,74,7,791-794 農化,74/,791-794,74,7,791-794 ,74,7,791-794 2000 Refereed Japanese Disclose to all
K. Ueda; T. Amachi K. Ueda; T. Amachi Molecular mechanism of defence to toxic substance Molecular mechanism of defence to toxic substance Nippon Nogeikagaku Kaishi,74,7,791-794 Nippon Nogeikagaku Kaishi,74,7,791-794 ,74,7,791-794 2000 Refereed Japanese Disclose to all
植田 和光 植田 和光 アプローチ:ABCタンパク質の多機能性と生体防御. アプローチ:ABCタンパク質の多機能性と生体防御. 最新医学,54/,352-359 最新医学,54/,352-359 1999 Refereed Japanese Disclose to all
植田 和光 植田 和光 トランスポーター型ABCタンパク質P糖タンパク質 トランスポーター型ABCタンパク質P糖タンパク質 最新医学,54/,360-365 最新医学,54/,360-365 1999 Refereed Japanese Disclose to all
植田 和光 植田 和光 薬剤耐性の分子生物学的機序 薬剤耐性の分子生物学的機序 炎症と免疫,7/,114-120 炎症と免疫,7/,114-120 1999 Refereed Japanese Disclose to all
植田 和光 植田 和光 MDR1/P-糖タンパク質の薬剤輸送の分子機構. MDR1/P-糖タンパク質の薬剤輸送の分子機構. 蛋白質核酸酵素,42/8,1263 蛋白質核酸酵素,42/8,1263 1997 Refereed Japanese Disclose to all
植田 和光 植田 和光 抗癌剤に対する膜輸送機構の変化を介した耐性獲得. 抗癌剤に対する膜輸送機構の変化を介した耐性獲得. 日本臨床,55/5,1024 日本臨床,55/5,1024 1997 Refereed Japanese Disclose to all
植田 和光 植田 和光 生体異物排出ポンプMDR1/P-糖タンパク質の分子機構. 生体異物排出ポンプMDR1/P-糖タンパク質の分子機構. 日本農芸化学会誌,71/8,785,71,8,785-788 日本農芸化学会誌,71/8,785,71,8,785-788 ,71,8,785-788 1997 Refereed Japanese Disclose to all
植田 和光 植田 和光 生体異物排出ポンプP-糖蛋白質とMRPの構造と活性-分子標的としての重要性- 生体異物排出ポンプP-糖蛋白質とMRPの構造と活性-分子標的としての重要性- 癌と化学療法,/,24 癌と化学療法,/,24 1997 Refereed Japanese Disclose to all
K. Ueda K. Ueda Molecular mechanisms for drug transport by MDR1/P-glycoprotein Molecular mechanisms for drug transport by MDR1/P-glycoprotein Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,42,8,1263-1272 Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,42,8,1263-1272 ,42,8,1263-1272 1997 Refereed Japanese Disclose to all
K. Ueda K. Ueda MDR 1/P-glycoprotein : An efflux pump of lipophilic xenobiotics MDR 1/P-glycoprotein : An efflux pump of lipophilic xenobiotics Nippon Nogeikagaku Kaishi,71,8,785-788 Nippon Nogeikagaku Kaishi,71,8,785-788 ,71,8,785-788 1997 Refereed Japanese Disclose to all
植田和光 植田和光 Family and super family of gene and proteins. Membrane transporter. ATP binding cassette transporter super family. Family and super family of gene and proteins. Membrane transporter. ATP binding cassette transporter super family. 生体の科学,46,5,596-598 生体の科学,46,5,596-598 ,46,5,596-598 1995/09 Refereed Japanese Disclose to all
植田和光 植田和光 P glyco proteins and anticancer drug resistance. P glyco proteins and anticancer drug resistance. Bio Clin,9,14,1063-1067 Bio Clin,9,14,1063-1067 ,9,14,1063-1067 1994/12 Refereed Japanese Disclose to all
植田和光;駒野徹 植田和光;駒野徹 Structure and function of multidrug resistance(MDR) gene. Structure and function of multidrug resistance(MDR) gene. 医学のあゆみ,167,3,147-149 医学のあゆみ,167,3,147-149 ,167,3,147-149 1993/10/16 Refereed Japanese Disclose to all
植田 和光 植田 和光 [要修正] MDRI遺伝子の構造と機能 [要修正] MDRI遺伝子の構造と機能 ,30,688-695 ,30,688-695 1993 Refereed Japanese Disclose to all
植田 和光 植田 和光 P-糖蛋白質 P-糖蛋白質 廣川タンパク質化学第2巻受容体タンパク質II,2,453-459 廣川タンパク質化学第2巻受容体タンパク質II,2,453-459 1993 Refereed Japanese Disclose to all
植田 和光 植田 和光 Pー糖蛋白質の遺伝子と機能 Pー糖蛋白質の遺伝子と機能 ,/10,8-14 ,/10,8-14 1993 Refereed Japanese Disclose to all
植田 和光 植田 和光 多剤耐性遺伝子MDR1 多剤耐性遺伝子MDR1 化学と生物,/30,410-411 化学と生物,/30,410-411 1992 Refereed Japanese Disclose to all
植田 和光 植田 和光 癌の多剤耐性に関与するヒトPー糖蛋白質の機能の解析 癌の多剤耐性に関与するヒトPー糖蛋白質の機能の解析 日本農芸化学会誌,/66,1617-1624,66,11,1617-1624 日本農芸化学会誌,/66,1617-1624,66,11,1617-1624 ,66,11,1617-1624 1992 Refereed Japanese Disclose to all
植田 和光 植田 和光 抗癌剤を細胞外に排出するPー糖蛋白質の本来の基質は何か 抗癌剤を細胞外に排出するPー糖蛋白質の本来の基質は何か 化学,/46,428-429 化学,/46,428-429 1991 Refereed Japanese Disclose to all
植田 和光 植田 和光 MDR1とPー糖蛋白質 MDR1とPー糖蛋白質 ,/6,301-306 ,/6,301-306 1990 Refereed Japanese Disclose to all
植田 和光 植田 和光 多剤耐性の分子機構 多剤耐性の分子機構 腫瘍と感染,/3,443-450 腫瘍と感染,/3,443-450 1990 Refereed Japanese Disclose to all
植田 和光 植田 和光 ヒト多剤耐性遺伝子を担うMDR1遺伝子の構造と機能 ヒト多剤耐性遺伝子を担うMDR1遺伝子の構造と機能 ファルマシア,/26,809-813 ファルマシア,/26,809-813 1990 Refereed Japanese Disclose to all
植田和光 植田和光 癌の多剤耐性はMDR1遺伝子が担っているのか? 癌の多剤耐性はMDR1遺伝子が担っているのか? 蛋白質 核酸 酵素,33,8,1287-1299 蛋白質 核酸 酵素,33,8,1287-1299 ,33,8,1287-1299 1988/07 Refereed Japanese Disclose to all
植田 和光 植田 和光 [要修正] 多剤耐性遺伝子MDR1. [要修正] 多剤耐性遺伝子MDR1. 癌と化学療法,/15,2858-2862 癌と化学療法,/15,2858-2862 1988 Refereed Japanese Disclose to all
植田 和光 植田 和光 多剤耐性遺伝子MDR1とその発見機構 多剤耐性遺伝子MDR1とその発見機構 細胞工学,/9,96-104 細胞工学,/9,96-104 1988 Refereed Japanese Disclose to all
A. Fojo; M. Cornwell; C. Cardarelli; D.P. Clark; N. Richert; D.-w. Shen; K. Ueda; M. Willingham; M.M. Gottesman; I. Pastan A. Fojo; M. Cornwell; C. Cardarelli; D.P. Clark; N. Richert; D.-w. Shen; K. Ueda; M. Willingham; M.M. Gottesman; I. Pastan Molecular biology of drug resistance [要修正] Molecular biology of drug resistance Breast Cancer Research and Treatment,9,1,5-16 ,9,1,5-16 Breast Cancer Research and Treatment,9,1,5-16 1987 Refereed English Disclose to all
植田 和光 植田 和光 ATP binding/hydrolysis by and phosphorylation of peroxisomal ABC proteins PMP70 (ABCD3) and ALDP (ABCD1). J. Biol. Chem. 277, 40142-40147 [要修正] ATP binding/hydrolysis by and phosphorylation of peroxisomal ABC proteins PMP70 (ABCD3) and ALDP (ABCD1). J. Biol. Chem. 277, 40142-40147 J. Biol. Chem. r,277, 40142-40147 J. Biol. Chem. r,277, 40142-40147 Refereed English Disclose to all
Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix. The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix. Journal of cell science,127,9,1875-1886 ,127,9,1875-1886 Journal of cell science,127,9,1875-1886 2014/05 Refereed Disclose to all
A. Kodan; T. Yamaguchi; T. Nakatsu; K. Sakiyama; C.J. Hipolito; A. Fujioka; R. Hirokane; K. Ikeguchi; B. Watanabe; J. Hiratake; Y. Kimura; H. Suga; K. Ueda; H. Kato A. Kodan; T. Yamaguchi; T. Nakatsu; K. Sakiyama; C.J. Hipolito; A. Fujioka; R. Hirokane; K. Ikeguchi; B. Watanabe; J. Hiratake; Y. Kimura; H. Suga; K. Ueda; H. Kato Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog Proceedings of the National Academy of Sciences of the United States of America,111,11,4049-4054 ,111,11,4049-4054 Proceedings of the National Academy of Sciences of the United States of America,111,11,4049-4054 2014 Refereed English Disclose to all
S. Kishino; M. Takeuchi; S.-B. Park; A. Hirata; N. Kitamura; J. Kunisawa; H. Kiyono; R. Iwamoto; Y. Isobe; M. Arita; H. Arai; K. Ueda; J. Shima; S. Takahashi; K. Yokozeki; S. Shimizu; J. Ogawa S. Kishino; M. Takeuchi; S.-B. Park; A. Hirata; N. Kitamura; J. Kunisawa; H. Kiyono; R. Iwamoto; Y. Isobe; M. Arita; H. Arai; K. Ueda; J. Shima; S. Takahashi; K. Yokozeki; S. Shimizu; J. Ogawa Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition Proceedings of the National Academy of Sciences of the United States of America,110,44,17808-17813 ,110,44,17808-17813 Proceedings of the National Academy of Sciences of the United States of America,110,44,17808-17813 2013/10/29 Refereed English Disclose to all
A. Matsuda; K. Nagao; M. Matsuo; N. Kioka; K. Ueda A. Matsuda; K. Nagao; M. Matsuo; N. Kioka; K. Ueda 24(S)-hydroxycholesterol is actively eliminated from neuronal cells by ABCA1 24(S)-hydroxycholesterol is actively eliminated from neuronal cells by ABCA1 Journal of Neurochemistry,126,1-2,93-101 ,126,1-2,93-101 Journal of Neurochemistry,126,1-2,93-101 2013/07 Refereed English Disclose to all
N. Takemoto; T. Suehara; H.L. Frisco; S.-I. Sato; T. Sezaki; K. Kusamori; Y. Kawazoe; S.M. Park; S. Yamazoe; Y. Mizuhata; R. Inoue; G.J. Miller; S.U. Hansen; G.C. Jayson; J.M. Gardiner; T. Kanaya; N. Tokitoh; K. Ueda; Y. Takakura; N. Kioka; M. Nishikawa; M. Uesugi N. Takemoto; T. Suehara; H.L. Frisco; S.-I. Sato; T. Sezaki; K. Kusamori; Y. Kawazoe; S.M. Park; S. Yamazoe; Y. Mizuhata; R. Inoue; G.J. Miller; S.U. Hansen; G.C. Jayson; J.M. Gardiner; T. Kanaya; N. Tokitoh; K. Ueda; Y. Takakura; N. Kioka; M. Nishikawa; M. Uesugi Small-molecule-induced clustering of heparan sulfate promotes cell adhesion Small-molecule-induced clustering of heparan sulfate promotes cell adhesion Journal of the American Chemical Society,135,30,11032-11039 ,135,30,11032-11039 Journal of the American Chemical Society,135,30,11032-11039 2013/07 Refereed English Disclose to all
N. Shitan; F. Dalmas; K. Dan; N. Kato; K. Ueda; F. Sato; C. Forestier; K. Yazaki N. Shitan; F. Dalmas; K. Dan; N. Kato; K. Ueda; F. Sato; C. Forestier; K. Yazaki Characterization of Coptis japonica CjABCB2, an ATP-binding cassette protein involved in alkaloid transport Characterization of Coptis japonica CjABCB2, an ATP-binding cassette protein involved in alkaloid transport Phytochemistry,91,109-116 ,91,109-116 Phytochemistry,91,109-116 2013/07 Refereed English Disclose to all
T. Sezaki; L. Tomiyama; Y. Kimura; K. Ueda; N. Kioka T. Sezaki; L. Tomiyama; Y. Kimura; K. Ueda; N. Kioka Dlg5 interacts with the TGF-β receptor and promotes its degradation Dlg5 interacts with the TGF-β receptor and promotes its degradation FEBS Letters,587,11,1624-1629 ,587,11,1624-1629 FEBS Letters,587,11,1624-1629 2013/06 Refereed English Disclose to all
M. Ishigami; Y. Tominaga; K. Nagao; Y. Kimura; M. Matsuo; N. Kioka; K. Ueda M. Ishigami; Y. Tominaga; K. Nagao; Y. Kimura; M. Matsuo; N. Kioka; K. Ueda ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1 ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1831,4,683-690 ,1831,4,683-690 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1831,4,683-690 2013/04 Refereed English Disclose to all
K.O. Nagata; C. Nakada; R.S. Kasai; A. Kusumi; K. Ueda K.O. Nagata; C. Nakada; R.S. Kasai; A. Kusumi; K. Ueda ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging Proceedings of the National Academy of Sciences of the United States of America,110,13,5034-5039 ,110,13,5034-5039 Proceedings of the National Academy of Sciences of the United States of America,110,13,5034-5039 2013/03/26 Refereed English Disclose to all
K. Nagao; M. Maeda; N.B. Mañucat; K. Ueda K. Nagao; M. Maeda; N.B. Mañucat; K. Ueda Cyclosporine A and PSC833 inhibit ABCA1 function via direct binding Cyclosporine A and PSC833 inhibit ABCA1 function via direct binding Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1831,2,398-406 ,1831,2,398-406 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1831,2,398-406 2013/02 Refereed English Disclose to all
H. Hirayama; Y. Kimura; N. Kioka; M. Matsuo; K. Ueda H. Hirayama; Y. Kimura; N. Kioka; M. Matsuo; K. Ueda ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin Journal of Lipid Research,54,2,496-502 ,54,2,496-502 Journal of Lipid Research,54,2,496-502 2013/02 Refereed English Disclose to all
S. Kanaoka; Y. Kimura; M. Fujikawa; Y. Nakagawa; K. Ueda; M. Akamatsu S. Kanaoka; Y. Kimura; M. Fujikawa; Y. Nakagawa; K. Ueda; M. Akamatsu Substrate recognition by P-glycoprotein efflux transporters: Structure-ATPase activity relationship of diverse chemicals and agrochemicals Substrate recognition by P-glycoprotein efflux transporters: Structure-ATPase activity relationship of diverse chemicals and agrochemicals Journal of Pesticide Science,38,3,112-122 ,38,3,112-122 Journal of Pesticide Science,38,3,112-122 2013 Refereed English Disclose to all
M. Tomioka; Y. Toda; J. Kurisu; Y. Kimura; M. Kengaku; K. Ueda M. Tomioka; Y. Toda; J. Kurisu; Y. Kimura; M. Kengaku; K. Ueda The effects of neurological disorder-related codon variations of ABCA13 on the function of the ABC protein The effects of neurological disorder-related codon variations of ABCA13 on the function of the ABC protein Bioscience, Biotechnology and Biochemistry,76,12,2289-2293 ,76,12,2289-2293 Bioscience, Biotechnology and Biochemistry,76,12,2289-2293 2012/12 Refereed English Disclose to all
S. Hulpke; M. Tomioka; E. Kremmer; K. Ueda; R. Abele; R. Tampé S. Hulpke; M. Tomioka; E. Kremmer; K. Ueda; R. Abele; R. Tampé Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC i peptide-loading complex Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC i peptide-loading complex Cellular and Molecular Life Sciences,69,19,3317-3327 ,69,19,3317-3327 Cellular and Molecular Life Sciences,69,19,3317-3327 2012/10 Refereed English Disclose to all
T. Sezaki; K. Inada; T. Sogabe; K. Kakuda; L. Tomiyama; Y. Matsuno; T. Ichikawa; M. Matsuo; K. Ueda; N. Kioka T. Sezaki; K. Inada; T. Sogabe; K. Kakuda; L. Tomiyama; Y. Matsuno; T. Ichikawa; M. Matsuo; K. Ueda; N. Kioka Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells PLoS ONE,7,4 ,7,4 PLoS ONE,7,4 2012/04/23 Refereed English Disclose to all
K. Nagao; Y. Kimura; K. Ueda K. Nagao; Y. Kimura; K. Ueda Lysine residues of ABCA1 are required for the interaction with apoA-I Lysine residues of ABCA1 are required for the interaction with apoA-I Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1821,3,530-535 ,1821,3,530-535 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1821,3,530-535 2012/03 Refereed English Disclose to all
K. Nagao; K. Takahashi; Y. Azuma; M. Takada; Y. Kimura; M. Matsuo; N. Kioka; K. Ueda K. Nagao; K. Takahashi; Y. Azuma; M. Takada; Y. Kimura; M. Matsuo; N. Kioka; K. Ueda ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding Journal of Lipid Research,53,1,126-136 ,53,1,126-136 Journal of Lipid Research,53,1,126-136 2012/01 Refereed English Disclose to all
K. Nagao; M. Tomioka; K. Ueda K. Nagao; M. Tomioka; K. Ueda Function and regulation of ABCA1 - Membrane meso-domain organization and reorganization Function and regulation of ABCA1 - Membrane meso-domain organization and reorganization FEBS Journal,278,18,3190-3203 ,278,18,3190-3203 FEBS Journal,278,18,3190-3203 2011/09 Refereed English Disclose to all
M. Hozoji-Inada; Y. Munehira; K. Nagao; N. Kioka; K. Ueda M. Hozoji-Inada; Y. Munehira; K. Nagao; N. Kioka; K. Ueda Liver X receptor β (LXRβ) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation Liver X receptor β (LXRβ) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation Journal of Biological Chemistry,286,22,20117-20124 ,286,22,20117-20124 Journal of Biological Chemistry,286,22,20117-20124 2011/06 Refereed English Disclose to all
H. Yamashita; K. Ueda; N. Kioka H. Yamashita; K. Ueda; N. Kioka WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions Journal of Biological Chemistry,286,5,3907-3914 ,286,5,3907-3914 Journal of Biological Chemistry,286,5,3907-3914 2011/02/04 Refereed English Disclose to all
M. Matsuo; R.B. Campenot; D.E. Vance; K. Ueda; J.E. Vance M. Matsuo; R.B. Campenot; D.E. Vance; K. Ueda; J.E. Vance Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1811,1,31-38 ,1811,1,31-38 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids,1811,1,31-38 2011/01 Refereed English Disclose to all
K. Ueda K. Ueda ABC proteins protect the human body and maintain optimal health ABC proteins protect the human body and maintain optimal health Bioscience, Biotechnology and Biochemistry,75,3,401-409 ,75,3,401-409 Bioscience, Biotechnology and Biochemistry,75,3,401-409 2011 Refereed English Disclose to all
Yamashita H., Ueda K., Kioka N. Yamashita H., Ueda K., Kioka N. WAVE2 forms a complex with cAMP-dependent protein kinase (PKA) and is involved in PKA enhancement of membrane protrusions. WAVE2 forms a complex with cAMP-dependent protein kinase (PKA) and is involved in PKA enhancement of membrane protrusions. J Biol Chem. 286, 3907–3914,286,5,3907-3914 ,286,5,3907-3914 J Biol Chem. 286, 3907–3914,286,5,3907-3914 2011 Refereed English Disclose to all
Hozoji-Inada M., Munehira Y., Nagao K., Kioka N., Ueda K. Hozoji-Inada M., Munehira Y., Nagao K., Kioka N., Ueda K. LXR directly interacts with ABCA1 to promote HDL formation during acute cholesterol accumulation. LXR directly interacts with ABCA1 to promote HDL formation during acute cholesterol accumulation. J. Biol. Chem. 286, 20117-24,286,22,20117-20124 ,286,22,20117-20124 J. Biol. Chem. 286, 20117-24,286,22,20117-20124 2011 Refereed English Disclose to all
K. Nagao; Y. Kimura; M. Mastuo; K. Ueda K. Nagao; Y. Kimura; M. Mastuo; K. Ueda Lipid outward translocation by ABC proteins Lipid outward translocation by ABC proteins FEBS Letters,584,13,2717-2723 ,584,13,2717-2723 FEBS Letters,584,13,2717-2723 2010/07/02 Refereed English Disclose to all
N. Kioka; T. Ito; H. Yamashita; N. Uekawa; T. Umemoto; S. Motoyoshi; H. Imai; K. Takahashi; H. Watanabe; M. Yamada; K. Ueda N. Kioka; T. Ito; H. Yamashita; N. Uekawa; T. Umemoto; S. Motoyoshi; H. Imai; K. Takahashi; H. Watanabe; M. Yamada; K. Ueda Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo Experimental Cell Research,316,10,1728-1738 ,316,10,1728-1738 Experimental Cell Research,316,10,1728-1738 2010/06/10 Refereed English Disclose to all
M. Shichiri; Y. Takanezawa; D.E. Rotzoll; Y. Yoshida; T. Kokubu; K. Ueda; H. Tamai; H. Arai M. Shichiri; Y. Takanezawa; D.E. Rotzoll; Y. Yoshida; T. Kokubu; K. Ueda; H. Tamai; H. Arai ATP-Binding cassette transporter A1 is involved in hepatic α-tocopherol secretion ATP-Binding cassette transporter A1 is involved in hepatic α-tocopherol secretion Journal of Nutritional Biochemistry,21,5,451-456 ,21,5,451-456 Journal of Nutritional Biochemistry,21,5,451-456 2010/05 Refereed English Disclose to all
K. Terakado; A. Kodan; H. Nakano; Y. Kimura; K. Ueda; T. Nakatsu; H. Kato K. Terakado; A. Kodan; H. Nakano; Y. Kimura; K. Ueda; T. Nakatsu; H. Kato Deleting two C-terminal α-helices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMP-PNP Deleting two C-terminal α-helices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMP-PNP Acta Crystallographica Section D: Biological Crystallography,66,319-323 ,66,319-323 Acta Crystallographica Section D: Biological Crystallography,66,319-323 2010/03 Refereed English Disclose to all
T. Umemoto; K. Tanaka; K. Ueda; N. Kioka T. Umemoto; K. Tanaka; K. Ueda; N. Kioka Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin Biochemical and Biophysical Research Communications,387,1,191-195 ,387,1,191-195 Biochemical and Biophysical Research Communications,387,1,191-195 2009/09/11 Refereed English Disclose to all
T. Sato; A. Kodan; Y. Kimura; K. Ueda; T. Nakatsu; H. Kato T. Sato; A. Kodan; Y. Kimura; K. Ueda; T. Nakatsu; H. Kato Functional role of the linker region in purified human P-glycoprotein Functional role of the linker region in purified human P-glycoprotein FEBS Journal,276,13,3504-3516 ,276,13,3504-3516 FEBS Journal,276,13,3504-3516 2009/07 Refereed English Disclose to all
T. Saeki; S. Mizushima; K. Ueda; K. Iwami; R. Kanamoto T. Saeki; S. Mizushima; K. Ueda; K. Iwami; R. Kanamoto Mutational analysis of uncharged polar residues and proline in the distal one-third (Thr<sup>130</sup>-Pro<sup>142</sup>) of the highly conserved region of mouse Slc10a2 Mutational analysis of uncharged polar residues and proline in the distal one-third (Thr<sup>130</sup>-Pro<sup>142</sup>) of the highly conserved region of mouse Slc10a2 Bioscience, Biotechnology and Biochemistry,73,7,1535-1540 ,73,7,1535-1540 Bioscience, Biotechnology and Biochemistry,73,7,1535-1540 2009/07 Refereed English Disclose to all
A. Kodan; H. Shibata; T. Matsumoto; K. Terakado; K. Sakiyama; M. Matsuo; K. Ueda; H. Kato A. Kodan; H. Shibata; T. Matsumoto; K. Terakado; K. Sakiyama; M. Matsuo; K. Ueda; H. Kato Improved expression and purification of human multidrug resistance protein MDR1 from baculovirus-infected insect cells Improved expression and purification of human multidrug resistance protein MDR1 from baculovirus-infected insect cells Protein Expression and Purification,66,1,7-14 ,66,1,7-14 Protein Expression and Purification,66,1,7-14 2009/07 Refereed English Disclose to all
T. Umemoto; T. Inomoto; K. Ueda; M. Hamaguchi; N. Kioka T. Umemoto; T. Inomoto; K. Ueda; M. Hamaguchi; N. Kioka v-Src-mediated transformation suppresses the expression of focal adhesion protein vinexin v-Src-mediated transformation suppresses the expression of focal adhesion protein vinexin Cancer Letters,279,1,22-29 ,279,1,22-29 Cancer Letters,279,1,22-29 2009/06/28 Refereed English Disclose to all
K. Nagao; Y. Zhao; K. Takahashi; Y. Kimura; K. Ueda K. Nagao; Y. Zhao; K. Takahashi; Y. Kimura; K. Ueda Sodium taurocholate-dependent lipid efflux by ABCA1: Effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation Sodium taurocholate-dependent lipid efflux by ABCA1: Effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation Journal of Lipid Research,50,6,1165-1172 ,50,6,1165-1172 Journal of Lipid Research,50,6,1165-1172 2009/06 Refereed English Disclose to all
Y. Azuma; M. Takada; M. Maeda; N. Kioka; K. Ueda Y. Azuma; M. Takada; M. Maeda; N. Kioka; K. Ueda The COP9 signalosome controls ubiquitinylation of ABCA1 The COP9 signalosome controls ubiquitinylation of ABCA1 Biochemical and Biophysical Research Communications,382,1,145-148 ,382,1,145-148 Biochemical and Biophysical Research Communications,382,1,145-148 2009/04/24 Refereed English Disclose to all
M. Hozoji; Y. Kimura; N. Kioka; K. Ueda M. Hozoji; Y. Kimura; N. Kioka; K. Ueda Formation of two intramolecular disulfide bonds is necessary for apoA-I-dependent cholesterol efflux mediated by ABCA1 Formation of two intramolecular disulfide bonds is necessary for apoA-I-dependent cholesterol efflux mediated by ABCA1 Journal of Biological Chemistry,284,17,11293-11300 ,284,17,11293-11300 Journal of Biological Chemistry,284,17,11293-11300 2009/04/24 Refereed English Disclose to all
T. Hirata; M. Okabe; A. Kobayashi; K. Ueda; M. Matsuo T. Hirata; M. Okabe; A. Kobayashi; K. Ueda; M. Matsuo Molecular mechanisms of subcellular localization of ABCG5 and ABCG8 Molecular mechanisms of subcellular localization of ABCG5 and ABCG8 Bioscience, Biotechnology and Biochemistry,73,3,619-626 ,73,3,619-626 Bioscience, Biotechnology and Biochemistry,73,3,619-626 2009/03 Refereed English Disclose to all
Y. Azuma; M. Takada; H.-W. Shin; N. Kioka; K. Nakayama; K. Ueda Y. Azuma; M. Takada; H.-W. Shin; N. Kioka; K. Nakayama; K. Ueda Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation Genes to Cells,14,2,191-204 ,14,2,191-204 Genes to Cells,14,2,191-204 2009/02 Refereed English Disclose to all
M. Maekawa; J. Kikuchi; K. Kotani; K. Nagao; T. Odgerel; K. Ueda; M. Kawano; Y. Furukawa; I. Sakurabayashi M. Maekawa; J. Kikuchi; K. Kotani; K. Nagao; T. Odgerel; K. Ueda; M. Kawano; Y. Furukawa; I. Sakurabayashi A novel missense mutation of ABCA1 in transmembrane α-helix in a Japanese patient with Tangier disease A novel missense mutation of ABCA1 in transmembrane α-helix in a Japanese patient with Tangier disease Atherosclerosis,206,1,216-222 ,206,1,216-222 Atherosclerosis,206,1,216-222 2009 Refereed English Disclose to all
S.-Y. Morita; K. Ueda; S. Kitagawa S.-Y. Morita; K. Ueda; S. Kitagawa Enzymatic measurement of phosphatidic acid in cultured cells Enzymatic measurement of phosphatidic acid in cultured cells Journal of Lipid Research,50,9,1945-1952 ,50,9,1945-1952 Journal of Lipid Research,50,9,1945-1952 2009 Refereed English Disclose to all
S.-i. Akanuma; S. Ohtsuki; Y. Doi; M. Tachikawa; S. Ito; S. Hori; T. Asashima; T. Hashimoto; K. Yamada; K. Ueda; T. Iwatsubo; T. Terasaki S.-i. Akanuma; S. Ohtsuki; Y. Doi; M. Tachikawa; S. Ito; S. Hori; T. Asashima; T. Hashimoto; K. Yamada; K. Ueda; T. Iwatsubo; T. Terasaki ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1-40) at the blood-brain barrier ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1-40) at the blood-brain barrier Neurochemistry International,52,6,956-961 ,52,6,956-961 Neurochemistry International,52,6,956-961 2008 Refereed English Disclose to all
A.R. Tanaka; F. Kano; K. Ueda; M. Murata A.R. Tanaka; F. Kano; K. Ueda; M. Murata The ABCA1 Q597R mutant undergoes trafficking from the ER upon ER stress The ABCA1 Q597R mutant undergoes trafficking from the ER upon ER stress Biochemical and Biophysical Research Communications,369,4,1174-1178 ,369,4,1174-1178 Biochemical and Biophysical Research Communications,369,4,1174-1178 2008 Refereed English Disclose to all
A.R. Tanaka; F. Kano; A. Yamamoto; K. Ueda; M. Murata A.R. Tanaka; F. Kano; A. Yamamoto; K. Ueda; M. Murata Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1 Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1 Genes to Cells,13,8,889-904 ,13,8,889-904 Genes to Cells,13,8,889-904 2008 Refereed English Disclose to all
Hozoi M., Munehira Y., Ikeda Y., Makishima M., Matsuo M., Koika N., Ueda K. Hozoi M., Munehira Y., Ikeda Y., Makishima M., Matsuo M., Koika N., Ueda K. Direct interaction of nuclear receptor LXRβ with ABCA1 modulates cholesterol efflux. Direct interaction of nuclear receptor LXRβ with ABCA1 modulates cholesterol efflux. J. Biol. Chem. 283, 30057–30063,283,44,30057-30063 ,283,44,30057-30063 J. Biol. Chem. 283, 30057–30063,283,44,30057-30063 2008 Refereed English Disclose to all
Y. Kimura; A. Kodan; M. Matsuo; K. Ueda Y. Kimura; A. Kodan; M. Matsuo; K. Ueda Cholesterol fill-in model: Mechanism for substrate recognition by ABC proteins Cholesterol fill-in model: Mechanism for substrate recognition by ABC proteins Journal of Bioenergetics and Biomembranes,39,5/6,447-452 ,39,5/6,447-452 Journal of Bioenergetics and Biomembranes,39,5/6,447-452 2007/12 Refereed English Disclose to all
K. Yasuhisa; M. Shin-ya; M. Michinori; U. Kazumitsu K. Yasuhisa; M. Shin-ya; M. Michinori; U. Kazumitsu Mechanism of multidrug recognition by MDR1/ABCB1 Mechanism of multidrug recognition by MDR1/ABCB1 Cancer Science,98,9,1303-1310 ,98,9,1303-1310 Cancer Science,98,9,1303-1310 2007/09 Refereed English Disclose to all
Y. Kimura; N. Kioka; H. Kato; M. Matsuo; K. Ueda Y. Kimura; N. Kioka; H. Kato; M. Matsuo; K. Ueda Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol Biochemical Journal,401,2,597-605 ,401,2,597-605 Biochemical Journal,401,2,597-605 2007/01/15 Refereed English Disclose to all
N. Shitan; M. Tanaka; K. Terai; K. Ueda; K. Yazaki N. Shitan; M. Tanaka; K. Terai; K. Ueda; K. Yazaki Human MDR1 and MRP1 recognize berberine as their transport substrate Human MDR1 and MRP1 recognize berberine as their transport substrate Bioscience, Biotechnology and Biochemistry,71,1,242-245 ,71,1,242-245 Bioscience, Biotechnology and Biochemistry,71,1,242-245 2007/01 Refereed English Disclose to all
M. Mitsushima; K. Ueda; N. Kioka M. Mitsushima; K. Ueda; N. Kioka Involvement of phosphatases in the anchorage-dependent regulation of ERK2 activation Involvement of phosphatases in the anchorage-dependent regulation of ERK2 activation Experimental Cell Research,313,9,1830-1838 ,313,9,1830-1838 Experimental Cell Research,313,9,1830-1838 2007 Refereed English Disclose to all
K. Nagao; K. Takahashi; K. Hanada; N. Kioka; M. Matsuo; K. Ueda K. Nagao; K. Takahashi; K. Hanada; N. Kioka; M. Matsuo; K. Ueda Enhanced ApoA-I-dependent cholesterol efflux by ABCA1 from sphingomyelin-deficient Chinese hamster ovary cells Enhanced ApoA-I-dependent cholesterol efflux by ABCA1 from sphingomyelin-deficient Chinese hamster ovary cells Journal of Biological Chemistry,282,20,14868-14874 ,282,20,14868-14874 Journal of Biological Chemistry,282,20,14868-14874 2007 Refereed English Disclose to all
S.-Y. Morita; A. Kobayashi; Y. Takanezawa; N. Kioka; T. Handa; H. Arai; M. Matsuo; K. Ueda S.-Y. Morita; A. Kobayashi; Y. Takanezawa; N. Kioka; T. Handa; H. Arai; M. Matsuo; K. Ueda Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4 Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4 Hepatology,46,1,188-199 ,46,1,188-199 Hepatology,46,1,188-199 2007 Refereed English Disclose to all
O. Sano; A. Kobayashi; K. Nagao; K. Kumagai; N. Kioka; K. Hanada; K. Ueda; M. Matsuo O. Sano; A. Kobayashi; K. Nagao; K. Kumagai; N. Kioka; K. Hanada; K. Ueda; M. Matsuo Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1 Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1 Journal of Lipid Research,48,11,2377-2384 ,48,11,2377-2384 Journal of Lipid Research,48,11,2377-2384 2007 Refereed English Disclose to all
T. Saeki; Y. Munetaka; K. Ueda; K. Iwami; R. Kanamoto T. Saeki; Y. Munetaka; K. Ueda; K. Iwami; R. Kanamoto Effects of Ala substitution for conserved cys residues in mouse ileal and hepatic Na<sup>+</sup>-dependent bile acid transporters Effects of Ala substitution for conserved cys residues in mouse ileal and hepatic Na<sup>+</sup>-dependent bile acid transporters Bioscience, Biotechnology and Biochemistry,71,8,1865-1872 ,71,8,1865-1872 Bioscience, Biotechnology and Biochemistry,71,8,1865-1872 2007 Refereed English Disclose to all
S. Tachibana; M. Hirano; T. Hirata; M. Matsuo; I. Ikeda; K. Ueda; R. Sato S. Tachibana; M. Hirano; T. Hirata; M. Matsuo; I. Ikeda; K. Ueda; R. Sato Cholesterol and plant sterol efflux from cultured intestinal epithelial cells is mediated by ATP-binding cassette transporters Cholesterol and plant sterol efflux from cultured intestinal epithelial cells is mediated by ATP-binding cassette transporters Bioscience, Biotechnology and Biochemistry,71,8,1886-1895 ,71,8,1886-1895 Bioscience, Biotechnology and Biochemistry,71,8,1886-1895 2007 Refereed English Disclose to all
Y. Matsumura; N. Ban; K. Ueda; N. Inagaki Y. Matsumura; N. Ban; K. Ueda; N. Inagaki Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency Journal of Biological Chemistry,281,45,34503-34514 ,281,45,34503-34514 Journal of Biological Chemistry,281,45,34503-34514 2006/11/10 Refereed English Disclose to all
K. Yazaki; N. Yamanaka; T. Masuno; S. Konagai; S. Kaneko; K. Ueda; F. Sato K. Yazaki; N. Yamanaka; T. Masuno; S. Konagai; S. Kaneko; K. Ueda; F. Sato Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation Plant Molecular Biology,61,3,491-503 ,61,3,491-503 Plant Molecular Biology,61,3,491-503 2006/06 Refereed English Disclose to all
K. Takahashi; Y. Kimura; N. Kioka; M. Matsuo; K. Ueda K. Takahashi; Y. Kimura; N. Kioka; M. Matsuo; K. Ueda Purification and ATPase activity of human ABCA1 Purification and ATPase activity of human ABCA1 Journal of Biological Chemistry,281,16,10760-10768 ,281,16,10760-10768 Journal of Biological Chemistry,281,16,10760-10768 2006/04/21 Refereed English Disclose to all
K. Mutoh; J. Mitsuhashi; Y. Kimura; S. Tsukahara; E. Ishikawa; K. Sai; S. Ozawa; J.-I. Sawada; K. Ueda; K. Katayama; Y. Sugimoto K. Mutoh; J. Mitsuhashi; Y. Kimura; S. Tsukahara; E. Ishikawa; K. Sai; S. Ozawa; J.-I. Sawada; K. Ueda; K. Katayama; Y. Sugimoto A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein Molecular Cancer Therapeutics,5,4,877-884 ,5,4,877-884 Molecular Cancer Therapeutics,5,4,877-884 2006/04 Refereed English Disclose to all
S. Abe-Dohmae; K. Ueda; S. Yokoyama S. Abe-Dohmae; K. Ueda; S. Yokoyama ABCA7, a molecule with unknown function ABCA7, a molecule with unknown function FEBS Letters,580,4,1178-1182 ,580,4,1178-1182 FEBS Letters,580,4,1178-1182 2006 Refereed English Disclose to all
M. Mitsushima; T. Sezaki; R. Akahane; K. Ueda; S. Suetsugu; T. Takenawa; N. Kioka M. Mitsushima; T. Sezaki; R. Akahane; K. Ueda; S. Suetsugu; T. Takenawa; N. Kioka Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin Genes to Cells,11,3,281-292 ,11,3,281-292 Genes to Cells,11,3,281-292 2006 Refereed English Disclose to all
M. Mitsushima; H. Takahashi; T. Shishido; K. Ueda; N. Kioka M. Mitsushima; H. Takahashi; T. Shishido; K. Ueda; N. Kioka Abl kinase interacts with and phosphorylates vinexin Abl kinase interacts with and phosphorylates vinexin FEBS Letters,580,17,4288-4295 ,580,17,4288-4295 FEBS Letters,580,17,4288-4295 2006 Refereed English Disclose to all
S. Abe-Dohmae; K.H. Kato; Y. Kumon; W. Hu; H. Ishigami; N. Iwamoto; M. Okazaki; C.-A. Wu; M. Tsujita; K. Ueda; S. Yokoyama S. Abe-Dohmae; K.H. Kato; Y. Kumon; W. Hu; H. Ishigami; N. Iwamoto; M. Okazaki; C.-A. Wu; M. Tsujita; K. Ueda; S. Yokoyama Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner Journal of Lipid Research,47,7,1542-1550 ,47,7,1542-1550 Journal of Lipid Research,47,7,1542-1550 2006 Refereed English Disclose to all
S. Nagao; K. Murao; H. Imachi; W.-M. Cao; X. Yu; J. Li; K. Matsumoto; T. Nishiuchi; R.A.M. Ahmed; N.C.W. Wong; K. Ueda; T. Ishida S. Nagao; K. Murao; H. Imachi; W.-M. Cao; X. Yu; J. Li; K. Matsumoto; T. Nishiuchi; R.A.M. Ahmed; N.C.W. Wong; K. Ueda; T. Ishida Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells FEBS Letters,580,18,4371-4376 ,580,18,4371-4376 FEBS Letters,580,18,4371-4376 2006 Refereed English Disclose to all
A. Kobayashi; Y. Takanezawa; T. Hirata; Y. Shimizu; K. Misasa; N. Kioka; H. Arai; K. Ueda; M. Matsuo A. Kobayashi; Y. Takanezawa; T. Hirata; Y. Shimizu; K. Misasa; N. Kioka; H. Arai; K. Ueda; M. Matsuo Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1 Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1 Journal of Lipid Research,47,8,1791-1802 ,47,8,1791-1802 Journal of Lipid Research,47,8,1791-1802 2006 Refereed English Disclose to all
M. Mitsushima; K. Ueda; N. Kioka M. Mitsushima; K. Ueda; N. Kioka Vinexin β regulates the phosphorylation of epidermal growth factor receptor on the cell surface Vinexin β regulates the phosphorylation of epidermal growth factor receptor on the cell surface Genes to Cells,11,9,971-982 ,11,9,971-982 Genes to Cells,11,9,971-982 2006 Refereed English Disclose to all
K. Yazaki; N. Yamanaka; T. Masuno; S. Konagai; N. Shitan; S. Kaneko; K. Ueda; F. Sato K. Yazaki; N. Yamanaka; T. Masuno; S. Konagai; N. Shitan; S. Kaneko; K. Ueda; F. Sato Erratum: Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation (Plant Molecular Biology (2006) 61, (3) (491-503) DOI: 10.1007/s11103-006-0024-9) Erratum: Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation (Plant Molecular Biology (2006) 61, (3) (491-503) DOI: 10.1007/s11103-006-0024-9) Plant Molecular Biology,61,6,961- ,61,6,961- Plant Molecular Biology,61,6,961- 2006 Refereed English Disclose to all
M. Matsuo; Y. Kimura; K. Ueda M. Matsuo; Y. Kimura; K. Ueda K<sub>ATP</sub> channel interaction with adenine nucleotides K<sub>ATP</sub> channel interaction with adenine nucleotides Journal of Molecular and Cellular Cardiology,38,6,907-916 ,38,6,907-916 Journal of Molecular and Cellular Cardiology,38,6,907-916 2005/06 Refereed English Disclose to all
A. Kobayashi; Y. Kimura; M. Matsuo; K. Ueda A. Kobayashi; Y. Kimura; M. Matsuo; K. Ueda ABC proteins as molecular targets for drug discovery ABC proteins as molecular targets for drug discovery Folia Pharmacologica Japonica,125,4,185-193 ,125,4,185-193 Folia Pharmacologica Japonica,125,4,185-193 2005 Refereed English Disclose to all
R. Arakawa; N. Tamehiro; T. Nishimaki-Mogami; K. Ueda; S. Yokoyama R. Arakawa; N. Tamehiro; T. Nishimaki-Mogami; K. Ueda; S. Yokoyama Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner Arteriosclerosis, Thrombosis, and Vascular Biology,25,6,1193-1197 ,25,6,1193-1197 Arteriosclerosis, Thrombosis, and Vascular Biology,25,6,1193-1197 2005 Refereed English Disclose to all
N. Ban; M. Sasaki; H. Sakai; K. Ueda; N. Inagaki N. Ban; M. Sasaki; H. Sakai; K. Ueda; N. Inagaki Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism Biochemical Journal,389,2,577-585 ,389,2,577-585 Biochemical Journal,389,2,577-585 2005 Refereed English Disclose to all
M. Hayashi; S. Abe-Dohmae; M. Okazaki; K. Ueda; S. Yokoyama M. Hayashi; S. Abe-Dohmae; M. Okazaki; K. Ueda; S. Yokoyama Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7 Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7 Journal of Lipid Research,46,8,1703-1711 ,46,8,1703-1711 Journal of Lipid Research,46,8,1703-1711 2005 Refereed English Disclose to all
H. Takahashi; M. Mitsushima; N. Okada; T. Ito; S. Aizawa; R. Akahane; T. Umemoto; K. Ueda; N. Kioka H. Takahashi; M. Mitsushima; N. Okada; T. Ito; S. Aizawa; R. Akahane; T. Umemoto; K. Ueda; N. Kioka Role of interaction with vinculin in recruitment of vinexins to focal adhesions Role of interaction with vinculin in recruitment of vinexins to focal adhesions Biochemical and Biophysical Research Communications,336,1,239-246 ,336,1,239-246 Biochemical and Biophysical Research Communications,336,1,239-246 2005 Refereed English Disclose to all
K. Takahashi; Y. Kimura; K. Nagata; A. Yamamoto; M. Matsuo; K. Ueda K. Takahashi; Y. Kimura; K. Nagata; A. Yamamoto; M. Matsuo; K. Ueda ABC proteins: Key molecules for lipid homeostasis ABC proteins: Key molecules for lipid homeostasis Medical Molecular Morphology,38,1,2-12 ,38,1,2-12 Medical Molecular Morphology,38,1,2-12 2005 Refereed English Disclose to all
Y. Toda; R. Aoki; Y. Ikeda; Y. Azuma; N. Kioka; M. Matsuo; M. Sakamoto; S. Mori; M. Fukumoto; K. Ueda Y. Toda; R. Aoki; Y. Ikeda; Y. Azuma; N. Kioka; M. Matsuo; M. Sakamoto; S. Mori; M. Fukumoto; K. Ueda Detection of ABCA7-positive cells in salivary glands from patients with Sjögren\\'s syndrome Detection of ABCA7-positive cells in salivary glands from patients with Sjögren\\'s syndrome Pathology International,55,10,639-643 ,55,10,639-643 Pathology International,55,10,639-643 2005 Refereed English Disclose to all
K. Nagata; A. Yamamoto; N. Ban; A.R. Tanaka; M. Matsuo; N. Kioka; N. Inagaki; K. Ueda K. Nagata; A. Yamamoto; N. Ban; A.R. Tanaka; M. Matsuo; N. Kioka; N. Inagaki; K. Ueda Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles Biochemical and Biophysical Research Communications,324,1,262-268 ,324,1,262-268 Biochemical and Biophysical Research Communications,324,1,262-268 2004/11/05 Refereed English Disclose to all
M. Mitsushima; A. Suwa; T. Amachi; K. Ueda; N. Kioka M. Mitsushima; A. Suwa; T. Amachi; K. Ueda; N. Kioka Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin Journal of Biological Chemistry,279,33,34570-34577 ,279,33,34570-34577 Journal of Biological Chemistry,279,33,34570-34577 2004/08/13 Refereed English Disclose to all
Y. Munehira; T. Ohnishi; S. Kawamoto; A. Furuya; K. Shitara; M. Imamura; T. Yokota; S. Takeda; T. Amachi; M. Matsuo; N. Kioka; K. Ueda Y. Munehira; T. Ohnishi; S. Kawamoto; A. Furuya; K. Shitara; M. Imamura; T. Yokota; S. Takeda; T. Amachi; M. Matsuo; N. Kioka; K. Ueda α1-Syntrophin Modulates Turnover of ABCA1 α1-Syntrophin Modulates Turnover of ABCA1 Journal of Biological Chemistry,279,15,15091-15095 ,279,15,15091-15095 Journal of Biological Chemistry,279,15,15091-15095 2004/04/09 Refereed English Disclose to all
Y. Kimura; S. Shibasaki; K. Morisato; N. Ishizuka; H. Minakuchi; K. Nakanishi; M. Matsuo; T. Amachi; M. Ueda; K. Ueda Y. Kimura; S. Shibasaki; K. Morisato; N. Ishizuka; H. Minakuchi; K. Nakanishi; M. Matsuo; T. Amachi; M. Ueda; K. Ueda Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column Microanalysis for MDR1 ATPase by high-performance liquid chromatography with a titanium dioxide column Analytical Biochemistry,326,2,262-266 ,326,2,262-266 Analytical Biochemistry,326,2,262-266 2004/03/15 Refereed English Disclose to all
Y. Kimura; M. Matsuo; K. Takahashi; T. Saeki; N. Kioka; T. Amachi; K. Ueda Y. Kimura; M. Matsuo; K. Takahashi; T. Saeki; N. Kioka; T. Amachi; K. Ueda ATP hydrolysis-dependent multidrug efflux transporter: MDR1/P-glycoprotein ATP hydrolysis-dependent multidrug efflux transporter: MDR1/P-glycoprotein Current Drug Metabolism,5,1,1-10 ,5,1,1-10 Current Drug Metabolism,5,1,1-10 2004/02 Refereed English Disclose to all
S. Abe-Dohmae; Y. Ikeda; M. Matsuo; M. Hayashi; K.-I. Okuhira; K. Ueda; S. Yokoyama S. Abe-Dohmae; Y. Ikeda; M. Matsuo; M. Hayashi; K.-I. Okuhira; K. Ueda; S. Yokoyama Human ABCA7 Supports Apolipoprotein-mediated Release of Cellular Cholesterol and Phospholipid to Generate High Density Lipoprotein Human ABCA7 Supports Apolipoprotein-mediated Release of Cellular Cholesterol and Phospholipid to Generate High Density Lipoprotein Journal of Biological Chemistry,279,1,604-611 ,279,1,604-611 Journal of Biological Chemistry,279,1,604-611 2004 Refereed English Disclose to all
S. Suzuki; T. Nishimaki-Mogami; N. Tamehiro; K. Inoue; R. Arakawa; S. Abe-Dohmae; A.R. Tanaka; K. Ueda; S. Yokoyama S. Suzuki; T. Nishimaki-Mogami; N. Tamehiro; K. Inoue; R. Arakawa; S. Abe-Dohmae; A.R. Tanaka; K. Ueda; S. Yokoyama Verapamil Increases the Apolipoprotein-Mediated Release of Cellular Cholesterol by Induction of ABCA1 Expression Via Liver X Receptor-Independent Mechanism Verapamil Increases the Apolipoprotein-Mediated Release of Cellular Cholesterol by Induction of ABCA1 Expression Via Liver X Receptor-Independent Mechanism Arteriosclerosis, Thrombosis, and Vascular Biology,24,3,519-525 ,24,3,519-525 Arteriosclerosis, Thrombosis, and Vascular Biology,24,3,519-525 2004 Refereed English Disclose to all
S. Sasawatari; M. Toki; T. Horie; Y. Nakano; T. Ikeda; K. Ueda; H. Fujise S. Sasawatari; M. Toki; T. Horie; Y. Nakano; T. Ikeda; K. Ueda; H. Fujise Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein Journal of Veterinary Medical Science,66,9,1079-1085 ,66,9,1079-1085 Journal of Veterinary Medical Science,66,9,1079-1085 2004 Refereed English Disclose to all
H. Fujise; S. Sasawatari; T. Annoura; T. Ikeda; K. Ueda H. Fujise; S. Sasawatari; T. Annoura; T. Ikeda; K. Ueda 3,3′,4,4′,5-Pentachlorobiphenyl inhibits drug efflux through P-glycoprotein in KB-3 cells expressing mutant human P-glycoprotein 3,3′,4,4′,5-Pentachlorobiphenyl inhibits drug efflux through P-glycoprotein in KB-3 cells expressing mutant human P-glycoprotein Journal of Biomedicine and Biotechnology,3,137-142 ,3,137-142 Journal of Biomedicine and Biotechnology,3,137-142 2004 Refereed English Disclose to all
Y. Ikeda; S. Abe-Dohmae; Y. Munehira; R. Aoki; S. Kawamoto; A. Furuya; K. Shitara; T. Amachi; N. Kioka; M. Matsuo; S. Yokoyama; K. Ueda Y. Ikeda; S. Abe-Dohmae; Y. Munehira; R. Aoki; S. Kawamoto; A. Furuya; K. Shitara; T. Amachi; N. Kioka; M. Matsuo; S. Yokoyama; K. Ueda Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release Biochemical and Biophysical Research Communications,311,2,313-318 ,311,2,313-318 Biochemical and Biophysical Research Communications,311,2,313-318 2003/11/14 Refereed English Disclose to all
M. Wakabayashi; T. Ito; M. Mitsushima; S. Aizawa; K. Ueda; T. Amachi; N. Kioka M. Wakabayashi; T. Ito; M. Mitsushima; S. Aizawa; K. Ueda; T. Amachi; N. Kioka Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and β-catenin at sites of cell-cell contact Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and β-catenin at sites of cell-cell contact Journal of Biological Chemistry,278,24,21709-21714 ,278,24,21709-21714 Journal of Biological Chemistry,278,24,21709-21714 2003/06/13 Refereed English Disclose to all
A.R. Tanaka; S. Abe-Dohmae; T. Ohnishi; R. Aoki; G. Morinaga; K.-I. Okuhira; Y. Ikeda; F. Kano; M. Matsuo; N. Kioka; T. Amachi; M. Murata; S. Yokoyama; K. Ueda A.R. Tanaka; S. Abe-Dohmae; T. Ohnishi; R. Aoki; G. Morinaga; K.-I. Okuhira; Y. Ikeda; F. Kano; M. Matsuo; N. Kioka; T. Amachi; M. Murata; S. Yokoyama; K. Ueda Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis Journal of Biological Chemistry,278,10,8815-8819 ,278,10,8815-8819 Journal of Biological Chemistry,278,10,8815-8819 2003/03/07 Refereed English Disclose to all
H. Umehara; Y. Nishii; M. Morishima; Y. Kakehi; N. Kioka; T. Amachi; J. Koizumi; M. Hagiwara; K. Ueda H. Umehara; Y. Nishii; M. Morishima; Y. Kakehi; N. Kioka; T. Amachi; J. Koizumi; M. Hagiwara; K. Ueda Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A Biochemical and Biophysical Research Communications,301,2,324-329 ,301,2,324-329 Biochemical and Biophysical Research Communications,301,2,324-329 2003/02/07 Refereed English Disclose to all
K. Terasaka; N. Shitan; F. Sato; F. Maniwa; K. Ueda; K. Yazaki K. Terasaka; N. Shitan; F. Sato; F. Maniwa; K. Ueda; K. Yazaki Application of vanadate-induced nucleotide trapping to plant cells for detection of ABC proteins Application of vanadate-induced nucleotide trapping to plant cells for detection of ABC proteins Plant and Cell Physiology,44,2,198-200 ,44,2,198-200 Plant and Cell Physiology,44,2,198-200 2003/02 Refereed English Disclose to all
N. Shitan; I. Bazin; K. Dan; K. Obata; K. Kigawa; K. Ueda; F. Sato; C. Forestier; K. Yazaki N. Shitan; I. Bazin; K. Dan; K. Obata; K. Kigawa; K. Ueda; F. Sato; C. Forestier; K. Yazaki Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica Proceedings of the National Academy of Sciences of the United States of America,100,2,751-756 ,100,2,751-756 Proceedings of the National Academy of Sciences of the United States of America,100,2,751-756 2003/01/21 Refereed English Disclose to all
Y. Sugimoto; S. Tsukahara; Y. Imai; Y. Sugimoto; K. Ueda; T. Tsuruo Y. Sugimoto; S. Tsukahara; Y. Imai; Y. Sugimoto; K. Ueda; T. Tsuruo Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists Molecular Cancer Therapeutics,2,1,105-112 ,2,1,105-112 Molecular Cancer Therapeutics,2,1,105-112 2003 Refereed English Disclose to all
A.R. Tanaka; K. Tanabe; M. Morita; M. Kurisu; Y. Kasiwayama; M. Matsuo; N. Kioka; T. Amachi; T. Imanaka; K. Ueda A.R. Tanaka; K. Tanabe; M. Morita; M. Kurisu; Y. Kasiwayama; M. Matsuo; N. Kioka; T. Amachi; T. Imanaka; K. Ueda ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1) ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1) Journal of Biological Chemistry,277,42,40142-40147 ,277,42,40142-40147 Journal of Biological Chemistry,277,42,40142-40147 2002/10/18 Refereed English Disclose to all
K. Sakai; N. Shitan; F. Sato; K. Ueda; K. Yazaki K. Sakai; N. Shitan; F. Sato; K. Ueda; K. Yazaki Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein Journal of Experimental Botany,53,376,1879-1886 ,53,376,1879-1886 Journal of Experimental Botany,53,376,1879-1886 2002/09 Refereed English Disclose to all
T. Ohama; K.-I. Hirano; Z. Zhang; R. Aoki; K.-I. Tsujii; Y. Nakagawa-Toyama; K. Tsukamoto; C. Ikegami; A. Matsuyama; M. Ishigami; N. Sakai; H. Hiraoka; K. Ueda; S. Yamashita; Y. Matsuzawa T. Ohama; K.-I. Hirano; Z. Zhang; R. Aoki; K.-I. Tsujii; Y. Nakagawa-Toyama; K. Tsukamoto; C. Ikegami; A. Matsuyama; M. Ishigami; N. Sakai; H. Hiraoka; K. Ueda; S. Yamashita; Y. Matsuzawa Dominant expression of ATP-binding cassette transporter-1 on basolateral surface of Caco-2 cells stimulated by LXR/RXR ligands Dominant expression of ATP-binding cassette transporter-1 on basolateral surface of Caco-2 cells stimulated by LXR/RXR ligands Biochemical and Biophysical Research Communications,296,3,625-630 ,296,3,625-630 Biochemical and Biophysical Research Communications,296,3,625-630 2002/08/23 Refereed English Disclose to all
M. Matsuo; M. Dabrowski; K. Ueda; F.M. Ashcroft M. Matsuo; M. Dabrowski; K. Ueda; F.M. Ashcroft Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding EMBO Journal,21,16,4250-4258 ,21,16,4250-4258 EMBO Journal,21,16,4250-4258 2002/08/15 Refereed English Disclose to all
A. Suwa; M. Mitsushima; T. Ito; M. Akamatsu; K. Ueda; T. Amachi; N. Kioka A. Suwa; M. Mitsushima; T. Ito; M. Akamatsu; K. Ueda; T. Amachi; N. Kioka Vinexin β regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor Vinexin β regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor Journal of Biological Chemistry,277,15,13053-13058 ,277,15,13053-13058 Journal of Biological Chemistry,277,15,13053-13058 2002/04/12 Refereed English Disclose to all
N. Kioka; K. Ueda; T. Amachi N. Kioka; K. Ueda; T. Amachi Vinexin, CAP/ponsin, ArgBP2: A novel adaptor protein family regulating cytoskeletal organization and signal transduction Vinexin, CAP/ponsin, ArgBP2: A novel adaptor protein family regulating cytoskeletal organization and signal transduction Cell Structure and Function,27,1,1-7 ,27,1,1-7 Cell Structure and Function,27,1,1-7 2002/02 Refereed English Disclose to all
H. Fujise; T. Annoura; S. Sasawatari; T. Ikeda; K. Ueda H. Fujise; T. Annoura; S. Sasawatari; T. Ikeda; K. Ueda Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein Chemosphere,46,9/10,1505-1511 ,46,9/10,1505-1511 Chemosphere,46,9/10,1505-1511 2002 Refereed English Disclose to all
K. Hashimoto; T. Uchiumi; T. Konno; T. Ebihara; T. Nakamura; M. Wada; S. Sakisaka; F. Maniwa; T. Amachi; K. Ueda; M. Kuwano K. Hashimoto; T. Uchiumi; T. Konno; T. Ebihara; T. Nakamura; M. Wada; S. Sakisaka; F. Maniwa; T. Amachi; K. Ueda; M. Kuwano Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome Hepatology,36,5,1236-1245 ,36,5,1236-1245 Hepatology,36,5,1236-1245 2002 Refereed English Disclose to all
植田 和光 植田 和光 Trafficking-defect and functional-defect by mutations of the ATP-binding domains in multidrug resistance protein 2 (MRP2, ABCC2) in patients with Dubin-Johnson syndrome. Trafficking-defect and functional-defect by mutations of the ATP-binding domains in multidrug resistance protein 2 (MRP2, ABCC2) in patients with Dubin-Johnson syndrome. Hepatology,36, 1236-1245 Hepatology,36, 1236-1245 2002 Refereed English Disclose to all
T. Kawauchi; M. Ikeya; S. Takada; K. Ueda; M. Shirai; Y. Takihara; N. Kioka; T. Amachi T. Kawauchi; M. Ikeya; S. Takada; K. Ueda; M. Shirai; Y. Takihara; N. Kioka; T. Amachi Expression of vinexin α in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal Expression of vinexin α in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal Mechanisms of Development,106,1-2,147-150 ,106,1-2,147-150 Mechanisms of Development,106,1-2,147-150 2001/08 Refereed English Disclose to all
Z.-S. Chen; S. Aoki; M. Komatsu; K. Ueda; T. Sumizawa; T. Furukawa; H. Okumura; X.-Q. Ren; M.G. Belinsky; K. Lee; G.D. Kruh; M. Kobayashi; S.-I. Akiyama Z.-S. Chen; S. Aoki; M. Komatsu; K. Ueda; T. Sumizawa; T. Furukawa; H. Okumura; X.-Q. Ren; M.G. Belinsky; K. Lee; G.D. Kruh; M. Kobayashi; S.-I. Akiyama Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol a on MRP1 function Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol a on MRP1 function International Journal of Cancer,93,1,107-113 ,93,1,107-113 International Journal of Cancer,93,1,107-113 2001/07/01 Refereed English Disclose to all
A.R. Tanaka; Y. Ikeda; S. Abe-Dohmae; R. Arakawa; K. Sadanami; A. Kidera; S. Nakagawa; T. Nagase; R. Aoki; N. Kioka; T. Amachi; S. Yokoyama; K. Ueda A.R. Tanaka; Y. Ikeda; S. Abe-Dohmae; R. Arakawa; K. Sadanami; A. Kidera; S. Nakagawa; T. Nagase; R. Aoki; N. Kioka; T. Amachi; S. Yokoyama; K. Ueda Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren\\'s syndrome Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren\\'s syndrome Biochemical and Biophysical Research Communications,283,5,1019-1025 ,283,5,1019-1025 Biochemical and Biophysical Research Communications,283,5,1019-1025 2001/05/25 Refereed English Disclose to all
K. Yazaki; N. Shitan; H. Takamatsu; K. Ueda; F. Sato K. Yazaki; N. Shitan; H. Takamatsu; K. Ueda; F. Sato A novel Coptis japonica multidrug-resistant protein preferentially expressed in the alkaloid-accumulating rhizome A novel Coptis japonica multidrug-resistant protein preferentially expressed in the alkaloid-accumulating rhizome Journal of Experimental Botany,52,357,877-879 ,52,357,877-879 Journal of Experimental Botany,52,357,877-879 2001 Refereed English Disclose to all
M. Matsuo; S. Trapp; Y. Tanizawa; N. Kioka; T. Amachi; Y. Oka; F.M. Ashcroft; K. Ueda M. Matsuo; S. Trapp; Y. Tanizawa; N. Kioka; T. Amachi; Y. Oka; F.M. Ashcroft; K. Ueda Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy Journal of Biological Chemistry,275,52,41184-41191 ,275,52,41184-41191 Journal of Biological Chemistry,275,52,41184-41191 2000/12/29 Refereed English Disclose to all
M. Matsuo; K. Tanabe; N. Kioka; T. Amachi; K. Ueda M. Matsuo; K. Tanabe; N. Kioka; T. Amachi; K. Ueda Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B Journal of Biological Chemistry,275,37,28757-28763 ,275,37,28757-28763 Journal of Biological Chemistry,275,37,28757-28763 2000/09/15 Refereed English Disclose to all
L.-X. Zhao; C.-J. Zhou; A. Tanaka; M. Nakata; T. Hirabayashi; T. Amachi; S. Shioda; K. Ueda; N. Inagaki L.-X. Zhao; C.-J. Zhou; A. Tanaka; M. Nakata; T. Hirabayashi; T. Amachi; S. Shioda; K. Ueda; N. Inagaki Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2 Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2 Biochemical Journal,350,3,865-872 ,350,3,865-872 Biochemical Journal,350,3,865-872 2000/09/15 Refereed English Disclose to all
K. Nagata; M. Nishitani; M. Matsuo; N. Kioka; T. Amachi; K. Ueda K. Nagata; M. Nishitani; M. Matsuo; N. Kioka; T. Amachi; K. Ueda Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1 Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1 Journal of Biological Chemistry,275,23,17626-17630 ,275,23,17626-17630 Journal of Biological Chemistry,275,23,17626-17630 2000/06/09 Refereed English Disclose to all
Y. Nishii; M. Morishima; Y. Kakehi; K. Umehara; N. Kioka; Y. Terano; T. Amachi; K. Ueda Y. Nishii; M. Morishima; Y. Kakehi; K. Umehara; N. Kioka; Y. Terano; T. Amachi; K. Ueda CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line FEBS Letters,465,2/3,153-156 ,465,2/3,153-156 FEBS Letters,465,2/3,153-156 2000/01/14 Refereed English Disclose to all
Y. Tanizawa; K. Matsuda; M. Matsuo; Y. Ohta; N. Ochi; M. Adachi; M. Koga; S. Mizuno; M. Kajita; Y. Tanaka; K. Tachibana; H. Inoue; S. Furukawa; T. Amachi; K. Ueda; Y. Oka Y. Tanizawa; K. Matsuda; M. Matsuo; Y. Ohta; N. Ochi; M. Adachi; M. Koga; S. Mizuno; M. Kajita; Y. Tanaka; K. Tachibana; H. Inoue; S. Furukawa; T. Amachi; K. Ueda; Y. Oka Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: Nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1 Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: Nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1 Diabetes,49,1,114-120 ,49,1,114-120 Diabetes,49,1,114-120 2000/01 Refereed English Disclose to all
K. Tanabe; S.J. Tucker; F.M. Ashcroft; P. Proks; N. Kioka; T. Amachi; K. Ueda K. Tanabe; S.J. Tucker; F.M. Ashcroft; P. Proks; N. Kioka; T. Amachi; K. Ueda Direct photoaffinity labeling of Kir6.2 by [γ-<sup>32</sup>P]ATP-[γ]4-azidoanilide Direct photoaffinity labeling of Kir6.2 by [γ-<sup>32</sup>P]ATP-[γ]4-azidoanilide Biochemical and Biophysical Research Communications,272,2,316-319 ,272,2,316-319 Biochemical and Biophysical Research Communications,272,2,316-319 2000 Refereed English Disclose to all
M. Matsuo; N. Kioka; T. Amachi; K. Ueda M. Matsuo; N. Kioka; T. Amachi; K. Ueda ATP binding properties of the nucleotide-binding folds of SUR1 ATP binding properties of the nucleotide-binding folds of SUR1 Journal of Biological Chemistry,274,52,37479-37482 ,274,52,37479-37482 Journal of Biological Chemistry,274,52,37479-37482 1999/12/24 Refereed English Disclose to all
M. Akamatsu; S.-I. Aota; A. Suwa; K. Ueda; T. Amachi; K.M. Yamada; S.K. Akiyama; N. Kioka M. Akamatsu; S.-I. Aota; A. Suwa; K. Ueda; T. Amachi; K.M. Yamada; S.K. Akiyama; N. Kioka Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities Journal of Biological Chemistry,274,50,35933-35937 ,274,50,35933-35937 Journal of Biological Chemistry,274,50,35933-35937 1999/12/10 Refereed English Disclose to all
K. Ueda; M. Matsuo; K. Tanabe; K. Morita; N. Kioka; T. Amachi K. Ueda; M. Matsuo; K. Tanabe; K. Morita; N. Kioka; T. Amachi Comparative aspects of the function and mechanism of SUR1 and MDR1 proteins Comparative aspects of the function and mechanism of SUR1 and MDR1 proteins Biochimica et Biophysica Acta - Biomembranes,1461,2,305-313 ,1461,2,305-313 Biochimica et Biophysica Acta - Biomembranes,1461,2,305-313 1999/12/06 Refereed English Disclose to all
T. Ashizawa; K. Kawashima; Y. Kanda; K. Goml; M. Okabe; K. Ueda; T. Tamaoki T. Ashizawa; K. Kawashima; Y. Kanda; K. Goml; M. Okabe; K. Ueda; T. Tamaoki Antitumor activity of KF22678, a novel thioester derivative of leinamycin Antitumor activity of KF22678, a novel thioester derivative of leinamycin Anti-Cancer Drugs,10,9,829-836 ,10,9,829-836 Anti-Cancer Drugs,10,9,829-836 1999/10 Refereed English Disclose to all
M. Matsuo; S.J. Tucker; F.M. Ashcroft; T. Amachi; K. Ueda M. Matsuo; S.J. Tucker; F.M. Ashcroft; T. Amachi; K. Ueda NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1 NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1 FEBS Letters,458,3,292-294 ,458,3,292-294 FEBS Letters,458,3,292-294 1999/09/24 Refereed English Disclose to all
S. Tsuruoka; K.-I. Sugimoto; K. Ueda; M. Suzuki; M. Imai; A. Fujimura S. Tsuruoka; K.-I. Sugimoto; K. Ueda; M. Suzuki; M. Imai; A. Fujimura Removal of digoxin and doxorubicin by multidrug resistance protein- overexpressed cell culture in hollow fiber Removal of digoxin and doxorubicin by multidrug resistance protein- overexpressed cell culture in hollow fiber Kidney International,56,1,154-163 ,56,1,154-163 Kidney International,56,1,154-163 1999/07 Refereed English Disclose to all
Z.-S. Chen; T. Furukawa; T. Sumizawa; K. Ono; K. Ueda; K. Seto; S.-I. Akiyama Z.-S. Chen; T. Furukawa; T. Sumizawa; K. Ono; K. Ueda; K. Seto; S.-I. Akiyama ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P Molecular Pharmacology,55,5,921-928 ,55,5,921-928 Molecular Pharmacology,55,5,921-928 1999/05 Refereed English Disclose to all
K. Ueda; A. Yoshida; T. Amachi K. Ueda; A. Yoshida; T. Amachi Recent progress in P-glycoprotein research Recent progress in P-glycoprotein research Anti-Cancer Drug Design,14,2,115-121 ,14,2,115-121 Anti-Cancer Drug Design,14,2,115-121 1999/04 Refereed English Disclose to all
K. Ueda; J. Komine; M. Matsuo; S. Seino; T. Amachi K. Ueda; J. Komine; M. Matsuo; S. Seino; T. Amachi Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide Proceedings of the National Academy of Sciences of the United States of America,96,4,1268-1272 ,96,4,1268-1272 Proceedings of the National Academy of Sciences of the United States of America,96,4,1268-1272 1999/02/16 Refereed English Disclose to all
K. Tanabe; S.J. Tucker; M. Matsuo; P. Proks; F.M. Ashcroft; S. Seino; T. Amachi; K. Ueda K. Tanabe; S.J. Tucker; M. Matsuo; P. Proks; F.M. Ashcroft; S. Seino; T. Amachi; K. Ueda Direct photoaffinity labeling of the Kir6.2 Subunit of the ATP-sensitive K<sup>+</sup> channel by 8-azido-ATP Direct photoaffinity labeling of the Kir6.2 Subunit of the ATP-sensitive K<sup>+</sup> channel by 8-azido-ATP Journal of Biological Chemistry,274,7,3931-3933 ,274,7,3931-3933 Journal of Biological Chemistry,274,7,3931-3933 1999/02/12 Refereed English Disclose to all
N. Kusunoki; K. Takara; Y. Tanigawara; A. Yamauchi; K. Ueda; F. Komada; Y. Ku; Y. Kuroda; Y. Saitoh; K. Okumura N. Kusunoki; K. Takara; Y. Tanigawara; A. Yamauchi; K. Ueda; F. Komada; Y. Ku; Y. Kuroda; Y. Saitoh; K. Okumura Inhibitory effects of a cyclosporin derivative, SDZ PSC 833, on transport of doxorubicin and vinblastine via human P-glycoprotein Inhibitory effects of a cyclosporin derivative, SDZ PSC 833, on transport of doxorubicin and vinblastine via human P-glycoprotein Japanese Journal of Cancer Research,89,11,1220-1228 ,89,11,1220-1228 Japanese Journal of Cancer Research,89,11,1220-1228 1998/11 Refereed English Disclose to all
Y. Takada; K. Yamada; Y. Taguchi; K. Kino; M. Matsuo; S.J. Tucker; T. Komano; T. Amachi; K. Ueda Y. Takada; K. Yamada; Y. Taguchi; K. Kino; M. Matsuo; S.J. Tucker; T. Komano; T. Amachi; K. Ueda Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein Biochimica et Biophysica Acta - Biomembranes,1373,1,131-136 ,1373,1,131-136 Biochimica et Biophysica Acta - Biomembranes,1373,1,131-136 1998/08/14 Refereed English Disclose to all
K. Ueda; N. Inagaki; S. Seino K. Ueda; N. Inagaki; S. Seino MgADP antagonism to Mg<sup>2+</sup>-independent ATP binding of the sulfonylurea receptor SUR1 MgADP antagonism to Mg<sup>2+</sup>-independent ATP binding of the sulfonylurea receptor SUR1 Journal of Biological Chemistry,272,37,22983-22986 ,272,37,22983-22986 Journal of Biological Chemistry,272,37,22983-22986 1997/09/12 Refereed English Disclose to all
Y. Taguchi; M. Morishima; T. Komano; K. Ueda Y. Taguchi; M. Morishima; T. Komano; K. Ueda Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity FEBS Letters,413,1,142-146 ,413,1,142-146 FEBS Letters,413,1,142-146 1997/08/11 Refereed English Disclose to all
Y. Taguchi; K. Kino; M. Morishima; T. Komano; S.E. Kane; K. Ueda Y. Taguchi; K. Kino; M. Morishima; T. Komano; S.E. Kane; K. Ueda Alteration of substrate specificity by mutations at the His<sup>61</sup> position in predicted transmembrane domain 1 of human MDR1/P-Glycoprotein Alteration of substrate specificity by mutations at the His<sup>61</sup> position in predicted transmembrane domain 1 of human MDR1/P-Glycoprotein Biochemistry,36,29,8883-8889 ,36,29,8883-8889 Biochemistry,36,29,8883-8889 1997/07/22 Refereed English Disclose to all
A. Miwa; K. Ueda; Y. Okada A. Miwa; K. Ueda; Y. Okada Protein kinase C-independent correlation between P-glycoprotein expression and volume sensitivity of Cl<sup>-</sup> channel Protein kinase C-independent correlation between P-glycoprotein expression and volume sensitivity of Cl<sup>-</sup> channel Journal of Membrane Biology,157,1,63-69 ,157,1,63-69 Journal of Membrane Biology,157,1,63-69 1997/05/01 Refereed English Disclose to all
K. Tanaka; M. Hirai; Y. Tanigawara; K. Ueda; M. Takano; R. Hori; K.-I. Inui K. Tanaka; M. Hirai; Y. Tanigawara; K. Ueda; M. Takano; R. Hori; K.-I. Inui Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK<sub>1</sub> cells transfected with human MDR1 gene Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK<sub>1</sub> cells transfected with human MDR1 gene Biochemical Pharmacology,53,5,741-746 ,53,5,741-746 Biochemical Pharmacology,53,5,741-746 1997/03/07 Refereed English Disclose to all
Y. Taguchi; A. Yoshida; Y. Takada; T. Komano; K. Ueda Y. Taguchi; A. Yoshida; Y. Takada; T. Komano; K. Ueda Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP) Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP) FEBS Letters,401,1,11-14 ,401,1,11-14 FEBS Letters,401,1,11-14 1997/01/13 Refereed English Disclose to all
Y. Okada; S. Oiki; M. Tominaga; M. Kubo; A. Miwa; T. Tominaga; T. Tsumura; K. Ueda Y. Okada; S. Oiki; M. Tominaga; M. Kubo; A. Miwa; T. Tominaga; T. Tsumura; K. Ueda Volume-sensitive Cl<sup>-</sup> channel in human epithelial cells: Regulation by ATP and relation to P-glycoprotein Volume-sensitive Cl<sup>-</sup> channel in human epithelial cells: Regulation by ATP and relation to P-glycoprotein Japanese Journal of Physiology,47,SUPPL. 1,S19-S20 ,47,SUPPL. 1,S19-S20 Japanese Journal of Physiology,47,SUPPL. 1,S19-S20 1997 Refereed English Disclose to all
K. Ueda; Y. Taguchi; M. Morishima K. Ueda; Y. Taguchi; M. Morishima How does P-glycoprotein recognize its substrates? How does P-glycoprotein recognize its substrates? Seminars in Cancer Biology,8,3,151-159 ,8,3,151-159 Seminars in Cancer Biology,8,3,151-159 1997 Refereed English Disclose to all
K. Kino; Y. Taguchi; K. Yamada; T. Komano; K. Ueda K. Kino; Y. Taguchi; K. Yamada; T. Komano; K. Ueda Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins FEBS Letters,399,1/2,29-32 ,399,1/2,29-32 FEBS Letters,399,1/2,29-32 1996/12/09 Refereed English Disclose to all
K. Tanaka; M. Hirai; Y. Tanigawara; M. Yasuhara; R. Hori; K. Ueda; K.-I. Inui K. Tanaka; M. Hirai; Y. Tanigawara; M. Yasuhara; R. Hori; K. Ueda; K.-I. Inui Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein Pharmaceutical Research,13,7,1073-1077 ,13,7,1073-1077 Pharmaceutical Research,13,7,1073-1077 1996/07 Refereed English Disclose to all
M. Hirai; K. Tanaka; T. Shimizu; Y. Tanigawara; M. Yasuhara; R. Hori; Y. Kakehi; O. Yoshida; K. Ueda; T. Komano; K.-I. Inui M. Hirai; K. Tanaka; T. Shimizu; Y. Tanigawara; M. Yasuhara; R. Hori; Y. Kakehi; O. Yoshida; K. Ueda; T. Komano; K.-I. Inui Cepharanthin, a multidrug resistant modifier, is a substrate for P- glycoprotein Cepharanthin, a multidrug resistant modifier, is a substrate for P- glycoprotein Journal of Pharmacology and Experimental Therapeutics,275,1,73-78 ,275,1,73-78 Journal of Pharmacology and Experimental Therapeutics,275,1,73-78 1995/10 Refereed English Disclose to all
K.T. Nguyen; B. Liu; K. Ueda; M.M. Gottesman; I. Pastan; K.-V. Chin K.T. Nguyen; B. Liu; K. Ueda; M.M. Gottesman; I. Pastan; K.-V. Chin Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants Oncology Research,6,2,71-77 ,6,2,71-77 Oncology Research,6,2,71-77 1994 Refereed English Disclose to all
K. Ueda; T. Saeki; M. Hirai; Y. Tanigawara; K. Tanaka; M. Okamura; M. Yasuhara; R. Hori; K. Inui; T. Komano K. Ueda; T. Saeki; M. Hirai; Y. Tanigawara; K. Tanaka; M. Okamura; M. Yasuhara; R. Hori; K. Inui; T. Komano Human P-glycoprotein as a multi-drug transporter analyzed by using transepithelial transport system. Human P-glycoprotein as a multi-drug transporter analyzed by using transepithelial transport system. Japanese Journal of Physiology,44,S67-S71 ,44,S67-S71 Japanese Journal of Physiology,44,S67-S71 1994 Refereed English Disclose to all
K. Ueda; A.M. Shimabuku; H. Konishi; Y. Fujii; S. Takebe; K. Nishi; M. Yoshida; T. Beppu; T. Komano K. Ueda; A.M. Shimabuku; H. Konishi; Y. Fujii; S. Takebe; K. Nishi; M. Yoshida; T. Beppu; T. Komano Functional expression of human P-glycoprotein in Schizosaccharomyces pombe Functional expression of human P-glycoprotein in Schizosaccharomyces pombe FEBS Letters,330,3,279-282 ,330,3,279-282 FEBS Letters,330,3,279-282 1993/09/20 Refereed English Disclose to all
N. Okamura; M. Hirai; Y. Tanigawara; K. Tanaka; M. Yasuhara; K. Ueda; T. Komano; R. Hori N. Okamura; M. Hirai; Y. Tanigawara; K. Tanaka; M. Yasuhara; K. Ueda; T. Komano; R. Hori Digoxin-cyclosporin A interaction: Modulation of the multidrug transporter P-glycoprotein in the kidney Digoxin-cyclosporin A interaction: Modulation of the multidrug transporter P-glycoprotein in the kidney Journal of Pharmacology and Experimental Therapeutics,266,3,1614-1619 ,266,3,1614-1619 Journal of Pharmacology and Experimental Therapeutics,266,3,1614-1619 1993/09 Refereed English Disclose to all
T. Saeki; K. Ueda; Y. Tanigawara; R. Hori; T. Komano T. Saeki; K. Ueda; Y. Tanigawara; R. Hori; T. Komano P-glycoprotein-mediated transcellular transport of MDR-reversing agents P-glycoprotein-mediated transcellular transport of MDR-reversing agents FEBS Letters,324,1,99-102 ,324,1,99-102 FEBS Letters,324,1,99-102 1993/06/07 Refereed English Disclose to all
T. Saeki; K. Ueda; Y. Tanigawara; R. Hori; T. Komano T. Saeki; K. Ueda; Y. Tanigawara; R. Hori; T. Komano Human P-glycoprotein transports cyclosporin A and FK506 Human P-glycoprotein transports cyclosporin A and FK506 Journal of Biological Chemistry,268,9,6077-6080 ,268,9,6077-6080 Journal of Biological Chemistry,268,9,6077-6080 1993/03/25 Refereed English Disclose to all
K. Ueda; N. Okamura; M. Hirai; Y. Tanigawara; T. Saeki; N. Kioka; T. Komano; R. Hori K. Ueda; N. Okamura; M. Hirai; Y. Tanigawara; T. Saeki; N. Kioka; T. Komano; R. Hori Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone Journal of Biological Chemistry,267,34,24248-24252 ,267,34,24248-24252 Journal of Biological Chemistry,267,34,24248-24252 1992/12/05 Refereed English Disclose to all
Y. Tanigawara; N. Okamura; M. Hirai; M. Yasuhara; K. Ueda; N. Kioka; T. Komano; R. Hori Y. Tanigawara; N. Okamura; M. Hirai; M. Yasuhara; K. Ueda; N. Kioka; T. Komano; R. Hori Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK<sub>1</sub>) Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK<sub>1</sub>) Journal of Pharmacology and Experimental Therapeutics,263,2,840-845 ,263,2,840-845 Journal of Pharmacology and Experimental Therapeutics,263,2,840-845 1992/11 Refereed English Disclose to all
I. Sugawara; A. Hirata; K. Ueda; S. Itoyama I. Sugawara; A. Hirata; K. Ueda; S. Itoyama Preparation and characterization of a murine monoclonal antibody (MDR3M) reactive with mdr3 gene product Preparation and characterization of a murine monoclonal antibody (MDR3M) reactive with mdr3 gene product Japanese Journal of Cancer Research,83,8,795-797 ,83,8,795-797 Japanese Journal of Cancer Research,83,8,795-797 1992/08 Refereed English Disclose to all
T. Saeki; A.M. Shimabuku; K. Ueda; T. Komano T. Saeki; A.M. Shimabuku; K. Ueda; T. Komano Specific drug binding by purified lipid-reconstituted P-glycoprotein: Dependence on the lipid composition Specific drug binding by purified lipid-reconstituted P-glycoprotein: Dependence on the lipid composition BBA - Biomembranes,1107,1,105-110 ,1107,1,105-110 BBA - Biomembranes,1107,1,105-110 1992/06/11 Refereed English Disclose to all
N. Kioka; N. Hosokawa; T. Komano; K. Hirayoshi; K. Nagate; K. Ueda N. Kioka; N. Hosokawa; T. Komano; K. Hirayoshi; K. Nagate; K. Ueda Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite FEBS Letters,301,3,307-309 ,301,3,307-309 FEBS Letters,301,3,307-309 1992/04/27 Refereed English Disclose to all
N. Kioka; Y. Yamano; T. Komano; K. Ueda N. Kioka; Y. Yamano; T. Komano; K. Ueda Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1) Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1) FEBS Letters,301,1,37-40 ,301,1,37-40 FEBS Letters,301,1,37-40 1992/04/13 Refereed English Disclose to all
A.M. Shimabuku; T. Nishimoto; K. Uedat; T. Komano A.M. Shimabuku; T. Nishimoto; K. Uedat; T. Komano P-glycoprotein: ATP hydrolysis by the N-terminal nucleotide-binding domain P-glycoprotein: ATP hydrolysis by the N-terminal nucleotide-binding domain Journal of Biological Chemistry,267,7,4308-4311 ,267,7,4308-4311 Journal of Biological Chemistry,267,7,4308-4311 1992/03/05 Refereed English Disclose to all
K. Ueda; H. Hiasa; S. Takebe; H. Sakai; T. Komano K. Ueda; H. Hiasa; S. Takebe; H. Sakai; T. Komano Alternative secondary structures in the phage G4 origin of the complementary DNA strand synthesis: effects of NaCl concentration on the bleomycin-DNA interaction. Alternative secondary structures in the phage G4 origin of the complementary DNA strand synthesis: effects of NaCl concentration on the bleomycin-DNA interaction. Bioscience, biotechnology, and biochemistry,56,3,394-398 ,56,3,394-398 Bioscience, biotechnology, and biochemistry,56,3,394-398 1992/03 Refereed English Disclose to all
I. Sugawara; M. Watanabe; A. Masunaga; S. Itoyama; K. Ueda I. Sugawara; M. Watanabe; A. Masunaga; S. Itoyama; K. Ueda Primer-dependent amplification of mdr1 mRNA by polymerase chain reaction Primer-dependent amplification of mdr1 mRNA by polymerase chain reaction Japanese Journal of Cancer Research,83,2,131-133 ,83,2,131-133 Japanese Journal of Cancer Research,83,2,131-133 1992/02 Refereed English Disclose to all
K.-V. Chin; K. Ueda; I. Pastan; M.M. Gottesman K.-V. Chin; K. Ueda; I. Pastan; M.M. Gottesman Modulation of activity of the promoter of the human MDR1 gene by Ras and p53 Modulation of activity of the promoter of the human MDR1 gene by Ras and p53 Science,255,5043,459-462 ,255,5043,459-462 Science,255,5043,459-462 1992/01/24 Refereed English Disclose to all
T. Saeki; A.M. Shimabuku; Y. Azuma; Y. Shibano; T. Komano; K. Ueda T. Saeki; A.M. Shimabuku; Y. Azuma; Y. Shibano; T. Komano; K. Ueda Expression of human P-glycoprotein in yeast cells--effects of membrane component sterols on the activity of P-glycoprotein. Expression of human P-glycoprotein in yeast cells--effects of membrane component sterols on the activity of P-glycoprotein. Agricultural and Biological Chemistry,55,7,1859-1865 ,55,7,1859-1865 Agricultural and Biological Chemistry,55,7,1859-1865 1991/07 Refereed English Disclose to all
A.M. Shimabuku; T. Saeki; K. Ueda; T. Komano A.M. Shimabuku; T. Saeki; K. Ueda; T. Komano Production of a site specifically cleavable P-glycoprotein-beta-galactosidase fusion protein. Production of a site specifically cleavable P-glycoprotein-beta-galactosidase fusion protein. Agricultural and Biological Chemistry,55,4,1075-1080 ,55,4,1075-1080 Agricultural and Biological Chemistry,55,4,1075-1080 1991/04 Refereed English Disclose to all
H. Kuroda; T. Sugimoto; K. Ueda; S. Tsuchida; Y. Horii; J. Inazawa; K. Sato; T. Sawada H. Kuroda; T. Sugimoto; K. Ueda; S. Tsuchida; Y. Horii; J. Inazawa; K. Sato; T. Sawada Different drug sensitivity in two neuroblastoma cell lines established from the same patient before and after chemotherapy Different drug sensitivity in two neuroblastoma cell lines established from the same patient before and after chemotherapy International Journal of Cancer,47,5,732-737 ,47,5,732-737 International Journal of Cancer,47,5,732-737 1991/03/12 Refereed English Disclose to all
I. Sugawara; T. Koji; K. Ueda; I. Pastan; M.M. Gottesman; P.K. Nakane; S. Mori I. Sugawara; T. Koji; K. Ueda; I. Pastan; M.M. Gottesman; P.K. Nakane; S. Mori In situ localization of the human multidrug-resistance gene mRNA using thymine-thymine dimerized single-stranded cDNA In situ localization of the human multidrug-resistance gene mRNA using thymine-thymine dimerized single-stranded cDNA Japanese Journal of Cancer Research,81,9,949-955 ,81,9,949-955 Japanese Journal of Cancer Research,81,9,949-955 1990/09 Refereed English Disclose to all
J.R. McLachlin; M.A. Eglitis; K. Ueda; P.W. Kantoff; I.H. Pastan; W.F. Anderson; M.M. Gottesman J.R. McLachlin; M.A. Eglitis; K. Ueda; P.W. Kantoff; I.H. Pastan; W.F. Anderson; M.M. Gottesman Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer Journal of the National Cancer Institute,82,15,1260-1263 ,82,15,1260-1263 Journal of the National Cancer Institute,82,15,1260-1263 1990/08/01 Refereed English Disclose to all
S. Tanaka; S.J. Currier; E.P. Bruggemann; K. Ueda; U.A. Germann; I. Pastan; M.M. Gottesman S. Tanaka; S.J. Currier; E.P. Bruggemann; K. Ueda; U.A. Germann; I. Pastan; M.M. Gottesman Use of recombinant P-glycoprotein fragments to produce antibodies to the multidrug transporter Use of recombinant P-glycoprotein fragments to produce antibodies to the multidrug transporter Biochemical and Biophysical Research Communications,166,1,180-186 ,166,1,180-186 Biochemical and Biophysical Research Communications,166,1,180-186 1990/01/15 Refereed English Disclose to all
L.J. Goldstein; A.T. Fojo; K. Ueda; W. Crist; A. Green; G. Brodeur; I. Pastan; M.M. Gottesman L.J. Goldstein; A.T. Fojo; K. Ueda; W. Crist; A. Green; G. Brodeur; I. Pastan; M.M. Gottesman Expression of the multidrug resistance, MDR1, gene in neuroblastomas Expression of the multidrug resistance, MDR1, gene in neuroblastomas Journal of Clinical Oncology,8,1,128-136 ,8,1,128-136 Journal of Clinical Oncology,8,1,128-136 1990/01 Refereed English Disclose to all
S. Kobayashi; K. Ueda; T. Komano S. Kobayashi; K. Ueda; T. Komano The effects of metal ions on the DNA damage induced by hydrogen peroxide. The effects of metal ions on the DNA damage induced by hydrogen peroxide. Agricultural and biological chemistry,54,1,69-76 ,54,1,69-76 Agricultural and biological chemistry,54,1,69-76 1990/01 Refereed English Disclose to all
C.-J. Chen; D. Clark; K. Ueda; I. Pastan; M.M. Gottesman; I.B. Roninson C.-J. Chen; D. Clark; K. Ueda; I. Pastan; M.M. Gottesman; I.B. Roninson Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins Journal of Biological Chemistry,265,1,506-514 ,265,1,506-514 Journal of Biological Chemistry,265,1,506-514 1990 Refereed English Disclose to all
K. Ueda; Y. Yamano; N. Kioka; Y. Kakehi; O. Yoshida; M.M. Gottesman; I. Pastan; T. Komano K. Ueda; Y. Yamano; N. Kioka; Y. Kakehi; O. Yoshida; M.M. Gottesman; I. Pastan; T. Komano Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay Japanese Journal of Cancer Research,80,11,1127-1132 ,80,11,1127-1132 Japanese Journal of Cancer Research,80,11,1127-1132 1989/11 Refereed English Disclose to all
S.J. Currier; K. Ueda; M.C. Willingham; I. Pastan; M.M. Gottesman S.J. Currier; K. Ueda; M.C. Willingham; I. Pastan; M.M. Gottesman Deletion and insertion mutants of the multidrug transporter Deletion and insertion mutants of the multidrug transporter Journal of Biological Chemistry,264,24,14376-14381 ,264,24,14376-14381 Journal of Biological Chemistry,264,24,14376-14381 1989/08/25 Refereed English Disclose to all
N. Kioka; J. Tsubota; Y. Kakehi; T. Komano; M.M. Gottesman; I. Pastan; K. Ueda N. Kioka; J. Tsubota; Y. Kakehi; T. Komano; M.M. Gottesman; I. Pastan; K. Ueda P-Glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly<sup>185</sup> with an altered pattern of multidrug resistance P-Glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly<sup>185</sup> with an altered pattern of multidrug resistance Biochemical and Biophysical Research Communications,162,1,224-231 ,162,1,224-231 Biochemical and Biophysical Research Communications,162,1,224-231 1989/07/14 Refereed English Disclose to all
S.E. Kane; B.R. Troen; S. Gal; K. Ueda; I. Pastan; M.M. Gottesman S.E. Kane; B.R. Troen; S. Gal; K. Ueda; I. Pastan; M.M. Gottesman Use of cloned multidrug resistance gene for coamplification and overproduction of major excreted protein,a transformation-regulated secreted acid protease Use of cloned multidrug resistance gene for coamplification and overproduction of major excreted protein,a transformation-regulated secreted acid protease Molecular and Cellular Biology,8,8,3316-3321 ,8,8,3316-3321 Molecular and Cellular Biology,8,8,3316-3321 1988/08 Refereed English Disclose to all
S. Kobayashi; K. Ueda; J. Morita; H. Sakai; T. Komano S. Kobayashi; K. Ueda; J. Morita; H. Sakai; T. Komano DNA damage induced by ascorbate in the presence of Cu<sup>2+</sup> DNA damage induced by ascorbate in the presence of Cu<sup>2+</sup> BBA - Gene Structure and Expression,949,1,143-147 ,949,1,143-147 BBA - Gene Structure and Expression,949,1,143-147 1988/01/25 Refereed English Disclose to all
I. Pastan; M.M. Gottesman; K. Ueda; E. Lovelace; A.V. Rutherford; M.C. Willingham I. Pastan; M.M. Gottesman; K. Ueda; E. Lovelace; A.V. Rutherford; M.C. Willingham A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells Proceedings of the National Academy of Sciences of the United States of America,85,12,4486-4490 ,85,12,4486-4490 Proceedings of the National Academy of Sciences of the United States of America,85,12,4486-4490 1988 Refereed English Disclose to all
K. Ueda; T. Komano K. Ueda; T. Komano The multidrug-resistance gene MDR1 The multidrug-resistance gene MDR1 Japanese Journal of Cancer and Chemotherapy,15,10,2858-2862 ,15,10,2858-2862 Japanese Journal of Cancer and Chemotherapy,15,10,2858-2862 1988 Refereed English Disclose to all
K. Ueda; I. Pastan; M.M. Gottesman K. Ueda; I. Pastan; M.M. Gottesman Isolation and sequence of the promotor region of the human multidrug-resistance (P-glycoprotein) gene Isolation and sequence of the promotor region of the human multidrug-resistance (P-glycoprotein) gene Journal of Biological Chemistry,262,36,17432-17436 ,262,36,17432-17436 Journal of Biological Chemistry,262,36,17432-17436 1987/12/25 Refereed English Disclose to all
K. Ueda; C. Cardarelli; M.M. Gottesman; T. Pastan K. Ueda; C. Cardarelli; M.M. Gottesman; T. Pastan Expression of a full-length cDNA for the human \\'MDR1\\' gene confers resistance to colchicine, doxorubicin, and vinblastine Expression of a full-length cDNA for the human \\'MDR1\\' gene confers resistance to colchicine, doxorubicin, and vinblastine Proceedings of the National Academy of Sciences of the United States of America,84,9,3004-3008 ,84,9,3004-3008 Proceedings of the National Academy of Sciences of the United States of America,84,9,3004-3008 1987/05 Refereed English Disclose to all
A.T. Fojo; K. Ueda; D.J. Slamon; D.G. Poplack; M.M. Gottesman; I. Pastan A.T. Fojo; K. Ueda; D.J. Slamon; D.G. Poplack; M.M. Gottesman; I. Pastan Expression of a multidrug-resistance gene in human tumors and tissues Expression of a multidrug-resistance gene in human tumors and tissues Proceedings of the National Academy of Sciences of the United States of America,84,1,265-269 ,84,1,265-269 Proceedings of the National Academy of Sciences of the United States of America,84,1,265-269 1987/01 Refereed English Disclose to all
植田 和光 植田 和光 The human multidrug resistance(mdrl)gene. The human multidrug resistance(mdrl)gene. The Journal of Biological Chemistry,262/2 The Journal of Biological Chemistry,262/2 1987 Refereed English Disclose to all
K. Ueda; M.M. Cornwell; M.M. Gottesman; I. Pastan; I.B. Roninson; V. Ling; J.R. Riordan K. Ueda; M.M. Cornwell; M.M. Gottesman; I. Pastan; I.B. Roninson; V. Ling; J.R. Riordan The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein Biochemical and Biophysical Research Communications,141,3,956-962 ,141,3,956-962 Biochemical and Biophysical Research Communications,141,3,956-962 1986/12/30 Refereed English Disclose to all
J. Morita; K. Ueda; S. Kobayashi; T. Komano J. Morita; K. Ueda; S. Kobayashi; T. Komano Sequence-specific modification of DNA by 6-hydroxybenzo[a]pyrene Sequence-specific modification of DNA by 6-hydroxybenzo[a]pyrene BBA - Gene Structure and Expression,868,1,87-90 ,868,1,87-90 BBA - Gene Structure and Expression,868,1,87-90 1986/10/16 Refereed English Disclose to all
植田 和光 植田 和光 Internal dupilication and homology with bacterial transport proteins in the mdrl (P-glycoprotein) gene from multidrug-resistance human cells Internal dupilication and homology with bacterial transport proteins in the mdrl (P-glycoprotein) gene from multidrug-resistance human cells Cell,47/7 Cell,47/7 1986 Refereed English Disclose to all
S. Nanjou; S. Fujii; J. Morita; K. Ueda; T. Komano S. Nanjou; S. Fujii; J. Morita; K. Ueda; T. Komano Sequence-specific alkali-labile lesions in DNA caused by d-isoglucosamine Sequence-specific alkali-labile lesions in DNA caused by d-isoglucosamine BBA - Gene Structure and Expression,866,1,44-52 ,866,1,44-52 BBA - Gene Structure and Expression,866,1,44-52 1986 Refereed English Disclose to all
C.-j. Chen; J.E. Chin; K. Ueda; D.P. Clark; I. Pastan; M.M. Gottesman; I.B. Roninson C.-j. Chen; J.E. Chin; K. Ueda; D.P. Clark; I. Pastan; M.M. Gottesman; I.B. Roninson Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Cell,47,3,381-389 ,47,3,381-389 Cell,47,3,381-389 1986 Refereed English Disclose to all
J. Morita; K. Ueda; S. Nanjo; T. Komanol J. Morita; K. Ueda; S. Nanjo; T. Komanol Sequence specific damage of DNA induced by reducing sugars Sequence specific damage of DNA induced by reducing sugars Nucleic Acids Research,13,2,449-458 ,13,2,449-458 Nucleic Acids Research,13,2,449-458 1985 Refereed English Disclose to all
NANJOU, S; FUJII, S; TANAKA, K; UEDA, K; KOMANO, T NANJOU, S; FUJII, S; TANAKA, K; UEDA, K; KOMANO, T INDUCTION OF SINGLE-STRAND SCISSION IN PHI-X174 RFI DNA BY D-ISOGLUCOSAMINE INDUCTION OF SINGLE-STRAND SCISSION IN PHI-X174 RFI DNA BY D-ISOGLUCOSAMINE AGRICULTURAL AND BIOLOGICAL CHEMISTRY,49,2,459-466 ,49,2,459-466 AGRICULTURAL AND BIOLOGICAL CHEMISTRY,49,2,459-466 1985 Refereed English Disclose to all
K. Ueda; S. Kobayashi; J. Morita; T. Komano K. Ueda; S. Kobayashi; J. Morita; T. Komano Site-specific DNA damage caused by lipid peroxidation products Site-specific DNA damage caused by lipid peroxidation products BBA - Gene Structure and Expression,824,4,341-348 ,824,4,341-348 BBA - Gene Structure and Expression,824,4,341-348 1985 Refereed English Disclose to all
K. Ueda; S. Kobayashi; H. Sakai; T. Komano K. Ueda; S. Kobayashi; H. Sakai; T. Komano Cleavage of stem-and-loop structure DNA by bleomycin. Reaction on the bacteriophage G4 origin of complementary strand synthesis Cleavage of stem-and-loop structure DNA by bleomycin. Reaction on the bacteriophage G4 origin of complementary strand synthesis Journal of Biological Chemistry,260,9,5804-5807 ,260,9,5804-5807 Journal of Biological Chemistry,260,9,5804-5807 1985 Refereed English Disclose to all
I. Saito; H. Sugiyama; T. Matsuura; K. Ueda; T. Komano I. Saito; H. Sugiyama; T. Matsuura; K. Ueda; T. Komano A new procedure for determining thymine residues in DNA sequencing. Photoinduced cleavage of DNA fragments in the presence of spermine A new procedure for determining thymine residues in DNA sequencing. Photoinduced cleavage of DNA fragments in the presence of spermine Nucleic Acids Research,12,6,2879-2885 ,12,6,2879-2885 Nucleic Acids Research,12,6,2879-2885 1984 Refereed English Disclose to all
K. Ueda; J. Morita; T. Komano K. Ueda; J. Morita; T. Komano Sequence specificity of heat-labile sites in DNA induced by mitomycin C Sequence specificity of heat-labile sites in DNA induced by mitomycin C Biochemistry,23,8,1634-1640 ,23,8,1634-1640 Biochemistry,23,8,1634-1640 1984 Refereed English Disclose to all
K. Ueda; T. Komano K. Ueda; T. Komano Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C Nucleic Acids Research,12,17,6673-6683 ,12,17,6673-6683 Nucleic Acids Research,12,17,6673-6683 1984 Refereed English Disclose to all
NANJOU, S; FUJII, S; TANAKA, K; UEDA, K; KOMANO, T NANJOU, S; FUJII, S; TANAKA, K; UEDA, K; KOMANO, T INDUCTION OF STRAND BREAKAGE IN PHI-X174 RFI DNA BY AMINOSUGAR DERIVATIVES INDUCTION OF STRAND BREAKAGE IN PHI-X174 RFI DNA BY AMINOSUGAR DERIVATIVES AGRICULTURAL AND BIOLOGICAL CHEMISTRY,48,11,2865-2867 ,48,11,2865-2867 AGRICULTURAL AND BIOLOGICAL CHEMISTRY,48,11,2865-2867 1984 Refereed English Disclose to all
MORITA, J; UEDA, K; NAKAI, K; BABA, Y; KOMANO, T MORITA, J; UEDA, K; NAKAI, K; BABA, Y; KOMANO, T DNA STRAND BREAKAGE INVITRO BY AUTOXIDIZED UNSATURATED FATTY-ACIDS DNA STRAND BREAKAGE INVITRO BY AUTOXIDIZED UNSATURATED FATTY-ACIDS AGRICULTURAL AND BIOLOGICAL CHEMISTRY,47,12,2977-2979 ,47,12,2977-2979 AGRICULTURAL AND BIOLOGICAL CHEMISTRY,47,12,2977-2979 1983 Refereed English Disclose to all
K. Ueda; J. Morita; T. Komano K. Ueda; J. Morita; T. Komano Actions of mitomycin C reduced with sodium borohydride on bacteriophage ∅X174 and its single- and double-stranded DNAs Actions of mitomycin C reduced with sodium borohydride on bacteriophage ∅X174 and its single- and double-stranded DNAs Agricultural and Biological Chemistry,46,6,1695-1697 ,46,6,1695-1697 Agricultural and Biological Chemistry,46,6,1695-1697 1982 Refereed English Disclose to all
K. Ueda; J. Morita; T. Komano K. Ueda; J. Morita; T. Komano Phage inactivation and DNA strand scission activities of 7-N-(p-hydroxyphenyl)mitomycin C Phage inactivation and DNA strand scission activities of 7-N-(p-hydroxyphenyl)mitomycin C Journal of Antibiotics,35,10,1380-1386 ,35,10,1380-1386 Journal of Antibiotics,35,10,1380-1386 1982 Refereed English Disclose to all
K. Ueda; J. Morita; T. Komano K. Ueda; J. Morita; T. Komano Induction of single strand scission in bacteriophage φX174 replicative form I DNA by mitomycin C Induction of single strand scission in bacteriophage φX174 replicative form I DNA by mitomycin C Journal of Antibiotics,34,3,317-322 ,34,3,317-322 Journal of Antibiotics,34,3,317-322 1981 Refereed English Disclose to all
K. Ueda; J. Morita; K. Yamashita; T. Komano K. Ueda; J. Morita; K. Yamashita; T. Komano Inactivation of bacteriophage øX174 by mitomycin C in the presence of sodium hydrosulfite and cupric ions Inactivation of bacteriophage øX174 by mitomycin C in the presence of sodium hydrosulfite and cupric ions Chemico-Biological Interactions,29,2,145-158 ,29,2,145-158 Chemico-Biological Interactions,29,2,145-158 1980 Refereed English Disclose to all

  • <<
  • >>
Title language:
Books etc
Author Author(Japanese) Author(English) Title Title(Japanese) Title(English) Publisher Publisher(Japanese) Publisher(English) Publication date Language Type Disclose
植田 和光 植田 和光 ABCトランスポーター-生体防御のABC-遺伝子から疾患まで. ABCトランスポーター-生体防御のABC-遺伝子から疾患まで. 診断と治療社, 診断と治療社, 2002 Japanese Disclose to all
植田 和光 植田 和光 ガン細胞の薬剤耐性機構 ガン細胞の薬剤耐性機構 In動物細胞細胞工学ハンドブック:朝倉書店, In動物細胞細胞工学ハンドブック:朝倉書店, 2001 Japanese Disclose to all
植田 和光 植田 和光 MDR1遺伝子を介した多剤耐性.In癌の薬剤耐性とその克服-基礎と臨床,大沼尚夫,and竹村譲eds. MDR1遺伝子を介した多剤耐性.In癌の薬剤耐性とその克服-基礎と臨床,大沼尚夫,and竹村譲eds. 宇宙堂八木書店,/,63-72 宇宙堂八木書店,/,63-72 2001 Japanese Disclose to all
植田 和光 植田 和光 Cell volume regulation. The molecular mechanism and volume sensing machinery. (共著) Cell volume regulation. The molecular mechanism and volume sensing machinery. (共著) Volume sesor anion channel., Volume sesor anion channel., 1998 Japanese Disclose to all
植田 和光 植田 和光 How does P-gp recognize its substrates? (共著) How does P-gp recognize its substrates? (共著) Seminars in Cancer Biology, Seminars in Cancer Biology, 1997 Japanese Disclose to all
植田 和光 植田 和光 多剤耐性の分子機構 多剤耐性の分子機構 羊土社 羊土社 1994 Japanese Disclose to all
植田 和光 植田 和光 脂溶性酸化物のDNA損傷作用及び脂溶性有害物質排出ポンプPー糖蛋白質(共著) 脂溶性酸化物のDNA損傷作用及び脂溶性有害物質排出ポンプPー糖蛋白質(共著) 食品の生体調節機能,/,319-330 食品の生体調節機能,/,319-330 1993 Japanese Disclose to all
植田 和光 植田 和光 ABCタンパク質:細胞のATPエンジン.In生体膜のエネルギー装置 ABCタンパク質:細胞のATPエンジン.In生体膜のエネルギー装置 バイオサイエンスの新世紀 共立出版,7 バイオサイエンスの新世紀 共立出版,7 Japanese Disclose to all
植田 和光 植田 和光 Role of P-glycoprotein in the transport of hormones and peptides. Role of P-glycoprotein in the transport of hormones and peptides. Multidrug resistance in cancer cells. (共著), Multidrug resistance in cancer cells. (共著), 1996 English Disclose to all
植田 和光 植田 和光 Substrates for P-glycoprotein in kidney Substrates for P-glycoprotein in kidney Transports in the liver (共著),/,223-232 Transports in the liver (共著),/,223-232 1994 English Disclose to all
Title language:
Awards
Title(Japanese) Title(English) Organization name(Japanese) Organization name(English) Date
日本農芸化学会奨励賞 日本農芸化学会 1992
日本農芸化学会賞 日本農芸化学会 2010/03
科学技術分野の文部科学大臣表彰科学技術賞 2017/07/
External funds, competitive funds and Grants-in-Aid for Scientific Research(kaken)
Type Position Title(Japanese) Title(English) Period
基盤研究(S) Representative 脂質輸送に関与するABC蛋白質の生理的基質と機能の解明 -
基盤研究(S) 脂質輸送に関与するABC蛋白質の生理的基質と機能の解明 2008-2012
基盤研究(A) Representative HDL(善玉コレステロール)形成の鍵をにぎるABC蛋白質の作用機構解明 2013-2015
基盤研究(S) Representative コレステロール恒常性の鍵をにぎるABC蛋白質の作用機構解明 2013-2017
基盤研究(S) Representative コレステロール恒常性の鍵をにぎるABC蛋白質の作用機構解明 (平成26年度分) 2014/04/01-2015/03/31
基盤研究(S) Representative コレステロール恒常性の鍵をにぎるABC蛋白質の作用機構解明 (平成27年度分) 2015/04/01-2016/03/31
基盤研究(S) Representative コレステロール恒常性の鍵をにぎるABC蛋白質の作用機構解明 (平成28年度分) 2016/04/01-2017/03/31
基盤研究(S) Representative コレステロール恒常性の鍵をにぎるABC蛋白質の作用機構解明 (平成29年度分) 2017/04/01-2018/03/31
基盤研究(S) Representative 脂質輸送型ABC蛋白質の謎に迫る Uncovering the secrets of lipid-transporting ABC protein 2018/61/1-2022/33/1
Non-external, competitive funds or grants other than grants-in-aid for Scientific research (kaken)
System Main person Title(Japanese) Title(English) Period
抗癌剤排出ポンプP-糖蛋白質の作用メカニズムの解明 Molecular mechanism of multidrug transporter P-glycoprotein -
ATP感受性K<sup>+</sup>チャンネルの分子メカニズム Molecular mechanism of ATP sensitine K<sup>+</sup> channel -
ABCタンパク質の分子メカニズム Molecular mechanism of ABC proteins -
脂質ホメオスタシスに関与するABC蛋白質の分子基盤 -
Teaching subject(s)
Name(Japanese) Name(English) Term Department Period
応用生命科学入門III 後期 農学部 2011/04-2012/03
分子生物学II 後期 農学部 2011/04-2012/03
細胞生化学専攻実験 農学研究科 2011/04-2012/03
細胞生化学専攻演習 農学研究科 2011/04-2012/03
応用生命科学 Applied Life Sciences 後期 全学共通科目 2011/04-2012/03
分子生物学Ⅱ Molecular BiologyII 後期 農学部 2012/04-2013/03
応用生命科学 Applied Life Sciences 後期 全学共通科目 2012/04-2013/03
応用生命科学入門III Introduction to Applied Life Science III 後期 農学部 2012/04-2013/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2012/04-2013/03
応用生命科学入門III Introduction to Applied Life Science III 後期 農学部 2013/04-2014/03
分子生物学Ⅱ Molecular BiologyII 後期 農学部 2013/04-2014/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2013/04-2014/03
細胞生化学講義 Cellular Biochemistry 後期集中 農学研究科 2013/04-2014/03
細胞生化学専攻演習 Cellular Biochemistry Seminar 通年 農学研究科 2013/04-2014/03
細胞生化学専攻実験 Experimental Course of Cellular Biochemistry 通年 農学研究科 2013/04-2014/03
応用生命科学 Applied Life Sciences 後期 全学共通科目 2013/04-2014/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2013/04-2014/03
応用生命科学入門III Introduction to Applied Life Science III 後期 農学部 2014/04-2015/03
分子生物学Ⅱ Molecular BiologyII 後期 農学部 2014/04-2015/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2014/04-2015/03
細胞生化学講義 Cellular Biochemistry 前期集中 農学研究科 2014/04-2015/03
Advanced Applied Biochemistry Advanced Applied Biochemistry 後期集中 農学研究科 2014/04-2015/03
細胞生化学専攻演習 Cellular Biochemistry Seminar 通年 農学研究科 2014/04-2015/03
細胞生化学専攻実験 Experimental Course of Cellular Biochemistry 通年 農学研究科 2014/04-2015/03
応用生命科学 Applied Life Sciences 後期 全学共通科目 2014/04-2015/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2014/04-2015/03
分子生物学Ⅱ Molecular BiologyII 後期 農学部 2015/04-2016/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2015/04-2016/03
応用生命科学入門III Introduction to Applied Life Science III 後期 農学部 2015/04-2016/03
細胞と物質をつなぐ科学 Integrated Cell-Material Sciences 後期 全学共通科目 2015/04-2016/03
細胞生化学専攻実験1 Experimental Course of Cellular Biochemistry1 通年 農学研究科 2015/04-2016/03
細胞生化学専攻実験 Experimental Course of Cellular Biochemistry 通年 農学研究科 2015/04-2016/03
細胞生化学専攻演習1 Cellular Biochemistry Seminar1 通年 農学研究科 2015/04-2016/03
細胞生化学専攻演習 Cellular Biochemistry Seminar 通年 農学研究科 2015/04-2016/03
細胞生化学講義 Cellular Biochemistry 前期集中 農学研究科 2015/04-2016/03
Advanced Applied Biochemistry Advanced Applied Biochemistry 後期集中 農学研究科 2016/04-2017/03
分子生物学Ⅱ Molecular BiologyII 後期 農学部 2016/04-2017/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2016/04-2017/03
細胞生化学専攻実験1 Experimental Course of Cellular Biochemistry1 通年 農学研究科 2016/04-2017/03
細胞生化学専攻実験2 Experimental Course of Cellular Biochemistry2 通年 農学研究科 2016/04-2017/03
細胞生化学専攻実験 Experimental Course of Cellular Biochemistry 通年 農学研究科 2016/04-2017/03
細胞生化学専攻演習1 Cellular Biochemistry Seminar1 通年 農学研究科 2016/04-2017/03
細胞生化学専攻演習2 Cellular Biochemistry Seminar2 通年 農学研究科 2016/04-2017/03
細胞生化学専攻演習 Cellular Biochemistry Seminar 通年 農学研究科 2016/04-2017/03
細胞生化学講義 Cellular Biochemistry 前期集中 農学研究科 2016/04-2017/03
分子生物学II Molecular BiologyII 後期 農学部 2017/04-2018/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2017/04-2018/03
細胞生化学専攻実験1 Experimental Course of Cellular Biochemistry1 通年 農学研究科 2017/04-2018/03
細胞生化学専攻実験2 Experimental Course of Cellular Biochemistry2 通年 農学研究科 2017/04-2018/03
細胞生化学専攻実験 Experimental Course of Cellular Biochemistry 通年 農学研究科 2017/04-2018/03
細胞生化学専攻演習1 Cellular Biochemistry Seminar1 通年 農学研究科 2017/04-2018/03
細胞生化学専攻演習2 Cellular Biochemistry Seminar2 通年 農学研究科 2017/04-2018/03
細胞生化学専攻演習 Cellular Biochemistry Seminar 通年 農学研究科 2017/04-2018/03
細胞生化学講義 Cellular Biochemistry 前期集中 農学研究科 2017/04-2018/03
Advanced Applied Biochemistry Advanced Applied Biochemistry 後期集中 農学研究科 2018/04-2019/03
分子生物学II Molecular BiologyII 後期 農学部 2018/04-2019/03
応用生命科学III Applied Life Sciences III 前期集中 全学共通科目 2018/04-2019/03
応用生命科学 III Applied Life Sciences III 前期集中 農学研究科 2018/04-2019/03
生理化学概論 Outline of Physiological Chemistry 後期集中 全学共通科目 2018/04-2019/03
細胞生化学専攻実験1 Experimental Course of Cellular Biochemistry1 通年 農学研究科 2018/04-2019/03
細胞生化学専攻実験2 Experimental Course of Cellular Biochemistry2 通年 農学研究科 2018/04-2019/03
細胞生化学専攻演習1 Cellular Biochemistry Seminar1 通年 農学研究科 2018/04-2019/03
細胞生化学専攻演習2 Cellular Biochemistry Seminar2 通年 農学研究科 2018/04-2019/03
細胞生化学講義 Cellular Biochemistry 前期集中 農学研究科 2018/04-2019/03

  • <<
  • >>
School management (title, position)
Title Period
大学入試センター試験実施委員会 委員 2017/04/01-2019/03/31
Faculty management (title, position)
Title Period
PI議長 2014/04/01-2015/03/31
農学研究科学部教務委員会 委員 2016/04/01-2018/03/31
農学研究科研究活動推進委員会 委員 2016/04/01-2018/03/31
Academic organizations (administrative title, position)
Organization name(Japanese) Organization name(English) Title(Japanese) Title(English) Period
日本農芸化学会 会長 President 2015/05/01-2017/04/30
日本生化学会 常任理事 2008/04/01-2010/03/31
日本生化学会 理事 2017/11/21-2019/11/20
日本農芸化学会 財務委員長 2017/05/01-2019/04/31
日本農学会 監事 2016/05/01-2018/04/31
日本脂質生化学会 幹事 2015/05/01-
Academic organizations (editor, editing team)
Organization name(Japanese) Organization name(English) Journal name(Japanese) Journal name(English) Title Period
日本農芸化学会 Japan Society forBioscience, Biotechnology, and Agrochemistry Bioscience Biotechnology and Biochemistry Bioscience Biotechnology and Biochemistry 編集委員長 2013/05/01-2014/12/31
Other activities (public organizations)
Committee(Japanese) Committee(English) Title Organization name Period
学術システム研究センター 主任研究員 日本学術振興会 2015/04/01-2018/03/31
学術システムセンター 主任研究員 日本学術振興会 2018/04/01-2019/03/31